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https://www.readbyqxmd.com/read/29054070/bedside-implantation-of-a-new-temporary-vena-cava-inferior-filter-safety-and-efficacy-results-of-the-european-angel-registry
#1
Stefan Baumann, Tobias Becher, Konstantinos Giannakopoulos, Claude Jabbour, Marlon Rutsch, Christian Fastner, Ibrahim El-Battrawy, Uzair Ansari, Dirk Lossnitzer, Michael Behnes, Angelika Alonso, Thomas Kirschning, Guido Michels, Daniel Stern, Ruediger Dissmann, Olaf Kueck, Fabio Silvio Taccone, Carl Waldmann, Nicholas Bunker, Maurizio Postiglione, Martin Borggrefe, Ibrahim Akin
PURPOSE: Pulmonary embolism (PE) is a frequently occurring complication in critically ill patients. Simultaneous occurrence of PE and life-threatening bleeding, may render medical anticoagulation impossible. For these patients, inferior vena cava filters (IVCF) present a valuable therapeutic alternative. The Angel® catheter is a novel IVCF that provides temporary protection from PE and is implanted at bedside. The primary objective of the European Angel® catheter registry is to evaluate the safety and efficacy of this IVCF...
October 12, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/29049961/smartphone-app-based-portable-sensor-for-the-detection-of-fluoro-surfactant-pfoa
#2
Cheng Fang, Xian Zhang, Zhaomin Dong, Liang Wang, Mallavarapu Megharaj, Ravi Naidu
We developed a smartphone app-based monitoring tool for the detection of anionic surfactants (AS), including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS). Akin to the methylene blue active substances (MBAS), liquid-phase extraction (LPE) is employed to extract the hydrophobic ion-pair of dye (ethyl violet)-AS to an organic phase (ethyl acetate). The colour (RGB) of the organic phase is read using a smartphone camera with the help of a reading kit. The value of RGB is carefully corrected and linked to the concentration of ASs with a standard deviation of <10% in the 10-1000 ppb (part per billion) range...
October 10, 2017: Chemosphere
https://www.readbyqxmd.com/read/29049074/physiology-and-role-of-intraocular-pressure-in-contemporary-anesthesia
#3
Dermot J Kelly, Sinéad M Farrell
More than 26 million Americans suffer with cataracts, and with 3.6 million cataract extractions performed annually in the United States, it is the most common surgical procedure. The integrity of the delicate structures of the eye that mediate vision is dependent on the intraocular pressure (IOP). Yet, IOP acts to compress the vessels within the globe-akin to a Starling resistor-and is a key component that determines the ocular perfusion pressure, defined as the difference between arterial pressure and IOP...
October 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29048567/green-fruited-solanum-habrochaites-lacks-fruit-specific-carotenogenesis-due-to-metabolic-and-structural-blocks
#4
Himabindu Vasuki Kilambi, Kalyani Manda, Avanish Rai, Chaitanya Charakana, Jayram Bagri, Rameshwar Sharma, Yellamaraju Sreelakshmi, Christine Raines
Members of the tomato clade exhibit a wide diversity in fruit color, but the mechanisms governing inter-species diversity of coloration are largely unknown. The carotenoid profiles, carotenogenic gene expression and proteome profiles of green-fruited Solanum habrochaites (SH), orange-fruited S. galapagense, and red-fruited S. pimpinellifolium were compared with cultivated tomato [S. lycopersicum cv. Ailsa Craig (SL)] to decipher the molecular basis of coloration diversity. Green-fruited SH, though it showed normal expression of chromoplast-specific phytoene synthase1 and lycopene β-cyclase genes akin to orange/red-fruited species, failed to accumulate lycopene and β-carotene...
October 13, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29048110/morphometric-and-morphologic-parameters-of-the-heart-in-healthy-alouatta-guariba-clamitans-cabrera-1940
#5
Murilo Gomes de Soutello Charlier, Maurício Gianfrancesco Filippi, Carolina Hagy Girotto, Vanessa Lanes Ribeiro, Carlos Roberto Teixeira, Maria Lúcia Gomes Lourenço, Luiz Carlos Vulcano
BACKGROUND: This study aimed at assessing the heart function of one neotropical primate (Alouatta guariba clamitans) kept in captivity using radiography, electrocardiogram (ECG) and Doppler echocardiography. METHODS: Ten adult healthy howler monkeys (A. g. clamitans) were evaluated under general anaesthesia. Vertebral Heart Scores (VHS) were obtained from radiographic studies. Ejection fraction, shortening fraction of left ventricle, left atrial/aortic root ratio, ascending aortic diameter, peak velocity of pulmonary, mitral, tricuspid and aortic blood flow and other values were measured by Doppler echocardiography...
October 19, 2017: Journal of Medical Primatology
https://www.readbyqxmd.com/read/29047097/from-physiological-redox-signalling-to-oxidant-stress
#6
Jeremy P T Ward
Oxidant stress is strongly associated with cardiovascular disease, including pulmonary hypertension, but antioxidant therapies have so far proven ineffective. This is partly due to a lack of understanding of the key role played by reactive oxygen species (ROS) in physiological cell signalling, and partly to the complex interrelationships between generators of ROS (e.g. mitochondria and NADPH oxidases, NOX), cellular antioxidant systems and indeed Ca(2+) signalling. At physiological levels ROS reversibly affect the function of numerous enzymes and transcription factors, most often via oxidation of specific protein thiols...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29044284/buckling-patterns-in-biaxially-pre-stretched-bilayer-shells-wrinkles-creases-folds-and-fracture-like-ridges
#7
Rashed Al-Rashed, Francisco López Jiménez, Joel Marthelot, Pedro M Reis
We introduce a new experimental system to study the effects of pre-stretch on the buckling patterns that emerge from the biaxial compression of elastomeric bilayer shells. Upon fabrication of the samples, releasing the pre-stretch in the substrate through deflation places the outer film in a state of biaxial compression and yields a variety of buckling patterns. We systematically explore the parameter space by varying the pre-stretch of the substrate and the ratio between the stiffness of the substrate and film...
October 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/29043506/fatigue-failure-of-the-cephalomedullary-nail-revision-options-outcomes-and-review-of-the-literature
#8
Adam Tucker, Michael Warnock, Sinead McDonald, Laurence Cusick, Andrew P Foster
Cephalomedullary nail (CMN) failure is a rare entity following hip fracture treatment. However, it poses significant challenges for revision surgery, both mechanically and biologically. Nail failure rates have been reported at < 2%; however, no published studies have reported revision surgery procedures and their respective outcomes. We present a regional experience, with outcomes, of the revision options. We identified 20 fatigued CMNs that underwent four different revision procedures. Mean age was 73 ± 15...
October 17, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29043293/classical-strong-metal-support-interactions-between-gold-nanoparticles-and-titanium-dioxide
#9
Hailian Tang, Yang Su, Bingsen Zhang, Adam F Lee, Mark A Isaacs, Karen Wilson, Lin Li, Yuegong Ren, Jiahui Huang, Masatake Haruta, Botao Qiao, Xin Liu, Changzi Jin, Dangsheng Su, Junhu Wang, Tao Zhang
Supported metal catalysts play a central role in the modern chemical industry but often exhibit poor on-stream stability. The strong metal-support interaction (SMSI) offers a route to control the structural properties of supported metals and, hence, their reactivity and stability. Conventional wisdom holds that supported Au cannot manifest a classical SMSI, which is characterized by reversible metal encapsulation by the support upon high-temperature redox treatments. We demonstrate a classical SMSI for Au/TiO2, evidenced by suppression of CO adsorption, electron transfer from TiO2 to Au nanoparticles, and gold encapsulation by a TiO x overlayer following high-temperature reduction (reversed by subsequent oxidation), akin to that observed for titania-supported platinum group metals...
October 2017: Science Advances
https://www.readbyqxmd.com/read/29043020/secondary-invasion-when-invasion-success-is-contingent-on-other-invaders-altering-the-properties-of-recipient-ecosystems
#10
REVIEW
Luke S O'Loughlin, Peter T Green
Positive interactions between exotic species may increase ecosystem-level impacts and potentially facilitate the entry and spread of other exotic species. Invader-facilitated invasion success-"secondary invasion"-is a key conceptual aspect of the well-known invasional meltdown hypothesis, but remains poorly defined and empirically underexplored. Drawing from heuristic models and published empirical studies, we explore this form of "secondary invasion" and discuss the phenomenon within the recognized conceptual framework of the determinants of invasion success...
October 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29042875/current-challenges-and-future-opportunities-for-child-and-adolescent-psychiatry-in-japan
#11
REVIEW
Masaru Tateno, Takahiko Inagaki, Takuya Saito, Anthony P S Guerrero, Norbert Skokauskas
Japan has been facing a serious shortfall of child and adolescent psychiatric workforce relative to increasing service needs. Likely because of a combination of limited workforce supply and limited trust or perception of effectiveness, mental health services are under-utilized by the educational and child welfare systems. Child and adolescent psychiatry (CAP) has not been a formally established specialty in Japan. The lack of basic structure in the specialty most likely contributes to a lack of training facilities, limited exposure to and interest in the specialty, and hence an inadequate workforce...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29042423/low-prevalence-of-inappropriate-shocks-in-patients-with-inherited-arrhythmia-syndromes-with-the-subcutaneous-implantable-defibrillator-single-center-experience-and-long-term-follow-up
#12
Boris Rudic, Erol Tülümen, Veronika Berlin, Susanne Röger, Ksenija Stach, Volker Liebe, Ibrahim El-Battrawy, Christina Dösch, Theano Papavassiliu, Ibrahim Akin, Martin Borggrefe, Jürgen Kuschyk
BACKGROUND: Up to 40% of patients with transvenous implantable cardioverter-defibrillator (ICD) experience lead-associated complications and may suffer from high complication rates when lead extraction is indicated. Subcutaneous ICD may represent a feasible alternative; however, the efficacy of the subcutaneous ICD in the detection and treatment of ventricular arrhythmias in patients with hereditary arrhythmia syndromes has not been fully evaluated. METHODS AND RESULTS: Patients with primary hereditary arrhythmia syndromes who fulfilled indication for defibrillator placement were eligible for enrollment...
October 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29042157/selective-inhibition-of-distracting-input
#13
REVIEW
MaryAnn Noonan, Ben Crittenden, Ole Jensen, Mark Stokes
We review a series of studies exploring distractor suppression. It is often assumed that preparatory distractor suppression is controlled via top-down mechanisms of attention akin to those that prepare brain areas for target enhancement. Here, we consider two alternative mechanisms: secondary inhibition and expectation suppression within a predictive coding framework. We draw on behavioural studies, evidence from neuroimaging and some animal studies. We conclude that there is very limited evidence for selective top-down control of preparatory inhibition...
October 14, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29041343/near-field-edge-fringes-at-sharp-material-boundaries
#14
V E Babicheva, S Gamage, M I Stockman, Y Abate
We have studied the formation of near-field fringes when sharp edges of materials are imaged using scattering-type scanning near-field optical microscope (s-SNOM). The materials we have investigated include dielectrics, metals, a near-perfect conductor, and those that possess anisotropic permittivity and hyperbolic dispersion. For our theoretical analysis, we use a technique that combines full-wave numerical simulations of tip-sample near-field interaction and signal demodulation at higher orders akin to what is done in typical s-SNOM experiments...
October 2, 2017: Optics Express
https://www.readbyqxmd.com/read/29039149/mastalgia-and-associated-factors-a-cross-sectional-study
#15
Deniz Koçoğlu, Serife Kurşun, Belgin Akın, Kamile Altuntug
OBJECTIVES: Mastalgia is a common and painful experience among women. This study aimed to determine the prevalence of breast pain, characteristics of the pain, and factors associated with breast pain, particularly those that can be changed. METHODS: This cross-sectional study comprised women aged from 18 to 65 years. In total, 752 women were included. Risk factors for breast pain were determined using logistic regression analysis with the entry model, and the risk factors for periodic and non-periodic breast pain were assessed using logistic regression analysis with the backward model...
July 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/29037445/effect-of-age-and-renal-function-on-survival-after-left-ventricular-assist-device-implantation
#16
Rahatullah Muslem, Kadir Caliskan, Sakir Akin, Yunus E Yasar, Kavita Sharma, Nisha A Gilotra, Isabella Kardys, Brian Houston, Glenn Whitman, Ryan J Tedford, Dennis A Hesselink, Ad J J C Bogers, Olivier C Manintveld, Stuart D Russell
Left ventricular assist devices (LVAD) are increasingly used, especially as destination therapy in in older patients. The aim of this study was to evaluate the effect of age on renal function and mortality in the first year after implantation. A retrospective multicenter cohort study was conducted, evaluating all LVAD patients implanted in the 2 participating centers (age ≥18 years). Patients were stratified according to the age groups <45, 45-54, 55-64, and ≥65 years old. Overall, 241 patients were included (mean age 52...
September 20, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29037158/genomic-divergence-and-cohesion-in-a-species-of-pelagic-freshwater-bacteria
#17
Matthias Hoetzinger, Martin W Hahn
BACKGROUND: In many prokaryotic genera a clustered phylogeny is observed, akin to the occurrence of species in sexually reproducing organisms. For some taxa, homologous recombination has been invoked as the underlying mechanism providing genomic cohesion among conspecific individuals. Whether this mechanism is applicable to prokaryotes in freshwaters with low habitat connectivity - i.e. elevated geographic barriers to gene flow - is unclear. To investigate further we studied genomic trends within the globally abundant PnecC cluster (genus Polynucleobacter, Betaproteobacteria) and analyzed homologous recombination within the affiliated species P...
October 16, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29035464/galectin-3-reflects-left-atrial-function-being-assessed-by-cardiac-magnetic-resonance-imaging
#18
Seung-Hyun Kim, Michael Behnes, Michele Natale, Sonja Hamed, Julia Hoffmann, Ursula Hoffmann, Johannes Budjan, Siegfried Lang, Martin Borggrefe, Theano Papavassiliu, Thomas Bertsch, Ibrahim Akin
BACKGROUND: This study aims to evaluate the association between galectin-3 and left atrial function (LAF) in patients undergoing cMRI. METHODS: Patients undergoing cMRI were prospectively enrolled. Right ventricular dysfunction (< 50%) was excluded. Blood samples for biomarker measurements of galectin-3 and NT-proBNP were collected at the time of cMRI examination. RESULTS: A total of 84 patients were included. Median LVEF was 59% (IQR 51 - 64%)...
October 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29035400/protein-recognition-by-a-pattern-generating-fluorescent-molecular-probe
#19
Zohar Pode, Ronny Peri-Naor, Joseph M Georgeson, Tal Ilani, Vladimir Kiss, Tamar Unger, Barak Markus, Haim M Barr, Leila Motiei, David Margulies
Fluorescent molecular probes have become valuable tools in protein research; however, the current methods for using these probes are less suitable for analysing specific populations of proteins in their native environment. In this study, we address this gap by developing a unimolecular fluorescent probe that combines the properties of small-molecule-based probes and cross-reactive sensor arrays (the so-called chemical 'noses/tongues'). On the one hand, the probe can detect different proteins by generating unique identification (ID) patterns, akin to cross-reactive arrays...
October 16, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/29032535/co-immunoprecipitation-for-identifying-protein-protein-interactions-in-borrelia-burgdorferi
#20
Henna Iqbal, Darrin R Akins, Melisha R Kenedy
Co-immunoprecipitation can be utilized to study protein-protein interactions from various environments, cell types, or tissues. Herein, we describe a co-immunoprecipitation protocol that can be used to examine protein complexes found in the pathogenic spirochete Borrelia burgdorferi. The method outlined here has successfully identified known and unknown members of borrelial protein complexes and is an efficient method for studying protein interactions in this pathogenic spirochete.
2018: Methods in Molecular Biology
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