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https://www.readbyqxmd.com/read/28210369/academic-primer-series-five-key-papers-for-consulting-clinician-educators
#1
Teresa M Chan, Michael Gottlieb, Antonia Quinn, Kory London, Lauren W Conlon, Felix Ankel
INTRODUCTION: Clinician educators are often asked to perform consultations for colleagues. Invitations to consult and advise others on local problems can help foster great collaborations between centers, and allows for an exchange of ideas between programs. In this article, the authors identify and summarize several key papers to assist emerging clinician educators with the consultation process. METHODS: A consensus-building process was used to generate a list of key papers that describe the importance and significance of educational consulting, informed by social media sources...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28210368/academic-primer-series-five-key-papers-about-team-collaboration-relevant-to-emergency-medicine
#2
Michael Gottlieb, Catherine Grossman, Emily Rose, William Sanderson, Felix Ankel, Anand Swaminathan, Teresa M Chan
INTRODUCTION: Team collaboration is an essential for success both within academics and the clinical environment. Often, team collaboration is not explicitly taught during medical school or even residency, and must be learned during one's early career. In this article, we aim to summarize five key papers about team collaboration for early career clinician educators. METHODS: We conducted a consensus-building process among the writing team to generate a list of key papers that describe the importance or significance of team collaboration, seeking input from social media sources...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28209284/recognizing-and-regulating-cannabis-as-a-temptation-good
#3
Jonathan P Caulkins
The U.S. appears to be on a path toward legalizing cannabis on the alcohol model, which is to say allowing for-profit corporations to produce, sell, and promote its use. Even after national legalization, it will take decades to observe the full effects on industry structure and behavior, or on use and misuse. However, we should not be surprised if after markets have matured and consumption patterns stabilized, legalization increases acute cannabis intoxication in the U.S. by 40 billion hours per year. This increase in use will be the most important cannabis-specific effect of legalization...
February 10, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28209184/arterial-access-site-complications-after-use-of-a-vascular-closure-device-related-to-puncture-height
#4
Benjamin Sartorius, Michael Behnes, Melike Ünsal, Ursula Hoffmann, Siegfried Lang, Kambis Mashayekhi, Martin Borggrefe, Ibrahim Akin
BACKGROUND: To analyze differences of access-site complications related to the height of femoral arterial puncture and the use of a vascular closure device (VCD) following percutaneous coronary intervention (PCI). METHODS: A subgroup of the FERARI study being treated by femoral arterial access and valuable inguinal angiography before implantation of a VCD were included. Inguinal angiographies were systematically reviewed by two independent cardiologists to determine the correct height of femoral arterial puncture...
February 16, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28205138/kant-s-epigenesis-specificity-and-developmental-constraints
#5
Boris Demarest
In this paper, I argue that Kant adopted, throughout his career, a position that is much more akin to classical accounts of epigenesis, although he does reject the more radical forms of epigenesis proposed in his own time, and does make use of preformationist sounding terms. I argue that this is because Kant (1) thinks of what is pre-formed as a species, not an individual or a part of an individual; (2) has no qualm with the idea of a specific, teleological principle or force underlying generation, and conceives of germs and predispositions as specific constraints on such a principle or force...
March 2017: History and Philosophy of the Life Sciences
https://www.readbyqxmd.com/read/28204185/steroid-hormones-are-key-modulators-of-tissue-mechanical-function-via-regulation-of-collagen-and-elastic-fibers
#6
Shanmugasundaram Nallasamy, Kyoko Yoshida, Meredith Akins, Kristin Myers, Renato Iozzo, Mala Mahendroo
No abstract text is available yet for this article.
February 13, 2017: Endocrinology
https://www.readbyqxmd.com/read/28195455/hydrolytic-stability-of-3-aminopropylsilane-coupling-agent-on-silica-and-silicate-surfaces-at-elevated-temperatures
#7
Denis V Okhrimenko, Akin Budi, Marcel Ceccato, Marite Cardenas, Dorte B Johansson, Dorthe Lybye, Klaus Bechgaard, Martin Peter Andersson, Susan L S Stipp
3-Aminopropylsilane (APS) coupling agent is widely used in industrial, biomaterial and medical applications to improve adhesion of polymers to inorganic materials. However, during exposure to elevated humidity and temperature, the deposited APS layers can decompose, leading to reduction in coupling efficiency and thus decreasing the product quality and the mechanical strength of the polymer-inorganic material interface. Therefore, a better understanding of the chemical state and stability of APS on inorganic surfaces is needed...
February 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28193259/acute-kidney-injury-increases-the-risk-of-end-stage-renal-disease-after-cardiac-surgery-in-an-asian-population-a-prospective-cohort-study
#8
Sophia Tsong Huey Chew, Roderica Rui Ge Ng, Weiling Liu, Khuan Yew Chow, Lian Kah Ti
BACKGROUND: Acute kidney injury (AKI) after cardiac surgery is associated with increased morbidity and mortality. The long-term association between AKI and end-stage renal disease (ESRD) in an Asian population is unknown. Given the high prevalence of diabetes and a younger age of presentation for cardiac surgery, it is important to track this progression of kidney disease. Therefore, we studied the long-term risk of ESRD and mortality in our Asian patients who developed AKI after cardiac surgery...
February 13, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28190628/reporting-bias-inflates-the-reputation-of-medical-treatments-a-comparison-of-outcomes-in-clinical-trials-and-online-product-reviews
#9
Mícheál de Barra
OBJECTIVES: People often hold unduly positive expectations about the outcomes of medicines and other healthcare products. Here the following explanation is tested: people who have a positive outcome tend to tell more people about their disease/treatment than people with poor or average outcomes. Akin to the file drawer problem in science, this systematically and positively distorts the information available to others. METHOD: If people with good treatment outcomes are more inclined to tell others, then they should also be more inclined to write online medical product reviews...
February 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28187186/structural-coalescence-underlies-the-aggregation-propensity-of-a-%C3%AE-barrel-protein-motif
#10
Carla R Angelani, Julio J Caramelo, Lucrecia M Curto, José M Delfino
A clear understanding of the structural foundations underlying protein aggregation is an elusive goal of central biomedical importance. A step toward this aim is exemplified by the β-barrel motif represented by the intestinal fatty acid binding protein (IFABP) and two abridged all-β sheet forms (Δ98Δ and Δ78Δ). At odds with the established notion that a perturbation of the native fold should necessarily favor a buildup of intermediate forms with an enhanced tendency to aggregate, the intrinsic stability (ΔG°H2O) of these proteins does not bear a straightforward correlation with their trifluoroethanol (TFE)-induced aggregation propensity...
2017: PloS One
https://www.readbyqxmd.com/read/28185079/-a%C3%A2-life-saving-shock-from-a%C3%A2-subcutaneous-icd-during-skydiving
#11
Stefan Baumann, Susanne Roeger, Tobias Becher, Ibrahim Akin, Martin Borggrefe, Juergen Kuschyk
We report the case of a 38-year-old man who was implanted a subcutaneous implantable cardioverter-defibrillator (S-ICD) and then performed a skydive from a height of 3000 m. During the jump, he lost consciousness due to ventricular fibrillation (VF). The S‑ICD detected the VF properly and successfully shocked the arrhythmia. Our illustrative case emphasizes the S‑ICD as an appropriate therapy in patient with life-threatening arrhythmias even under extreme conditions.
February 9, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/28183685/a-case-of-leukemia-cutis-with-acute-myeloid-leukemia-on-azacitidine-therapy
#12
Asude Kara, Aslı Akın Belli, Volkan Karakuş, Yelda Dere, Erdal Kurtoğlu
No abstract text is available yet for this article.
February 9, 2017: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28180122/acute-kidney-injury-risk-factors-for-icu-patients-following-cardiac-surgery-the-application-of-joint-modeling
#13
Batoul Khoundabi, Anoshirvan Kazemnejad, Marjan Mansourian, Seyed Mohammadreza Hashemian, Mehdi Kazempoor Dizaji
BACKGROUND: Admission to the ICU (intensive care unit) is frequently complicated by early AKI (acute kidney injury). The development of AKI following cardiac surgery is particularly associated with increased mortality and morbidity. According to AKIN (acute kidney injury network) criteria, UO (urinary output) is a predictor for AKI. OBJECTIVES: The goal of this study was to determine the effects of some AKI risk factors on AKI and also to investigate changes in UO as a predictor of AKI using joint modeling...
September 2016: Trauma Monthly
https://www.readbyqxmd.com/read/28179180/developing-a-3-choice-serial-reaction-time-task-for-examining-neural-and-cognitive-function-in-an-equine-model
#14
Kirsty Roberts, Andrew J Hemmings, Sebastian D McBride, Matthew O Parker
BACKGROUND: Large animal models of human neurological disorders are advantageous compared to rodent models due to their neuroanatomical complexity, longevity and their ability to be maintained in naturalised environments. Some large animal models spontaneously develop behaviours that closely resemble the symptoms of neural and psychiatric disorders. The horse is an example of this; the domestic form of this species consistently develops spontaneous stereotypic behaviours akin to the compulsive and impulsive behaviours observed in human neurological disorders such as Tourette's syndrome...
February 5, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28177993/effects-of-hysterectomy-on-pelvic-floor-disorders-a-longitudinal-study
#15
Akin Firat Kocaay, Derya Oztuna, Filiz Akin Su, Atilla Halil Elhan, Mehmet Ayhan Kuzu
BACKGROUND: Hysterectomy might adversely affect pelvic floor functions and result in many different symptoms, such as urinary and anal incontinence, obstructed defecation, and constipation. OBJECTIVE: The aim of this prospective study was to evaluate the influence of hysterectomy on pelvic floor disorders. DESIGN: This was a prospective and longitudinal study. SETTINGS: The study was conducted at the Ankara University Department of Surgery and the Dr Zekai Tahir Burak Women's Health Research and Education Hospital between September 2008 and March 2011...
March 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28176862/laser-plasma-based-space-radiation-reproduction-in-the-laboratory
#16
B Hidding, O Karger, T Königstein, G Pretzler, G G Manahan, P McKenna, R Gray, R Wilson, S M Wiggins, G H Welsh, A Beaton, P Delinikolas, D A Jaroszynski, J B Rosenzweig, A Karmakar, V Ferlet-Cavrois, A Costantino, M Muschitiello, E Daly
Space radiation is a great danger to electronics and astronauts onboard space vessels. The spectral flux of space electrons, protons and ions for example in the radiation belts is inherently broadband, but this is a feature hard to mimic with conventional radiation sources. Using laser-plasma-accelerators, we reproduced relativistic, broadband radiation belt flux in the laboratory, and used this man-made space radiation to test the radiation hardness of space electronics. Such close mimicking of space radiation in the lab builds on the inherent ability of laser-plasma-accelerators to directly produce broadband Maxwellian-type particle flux, akin to conditions in space...
February 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28176794/x-linked-primary-ciliary-dyskinesia-due-to-mutations-in-the-cytoplasmic-axonemal-dynein-assembly-factor-pih1d3
#17
Chiara Olcese, Mitali P Patel, Amelia Shoemark, Santeri Kiviluoto, Marie Legendre, Hywel J Williams, Cara K Vaughan, Jane Hayward, Alice Goldenberg, Richard D Emes, Mustafa M Munye, Laura Dyer, Thomas Cahill, Jeremy Bevillard, Corinne Gehrig, Michel Guipponi, Sandra Chantot, Philippe Duquesnoy, Lucie Thomas, Ludovic Jeanson, Bruno Copin, Aline Tamalet, Christel Thauvin-Robinet, Jean-François Papon, Antoine Garin, Isabelle Pin, Gabriella Vera, Paul Aurora, Mahmoud R Fassad, Lucy Jenkins, Christopher Boustred, Thomas Cullup, Mellisa Dixon, Alexandros Onoufriadis, Andrew Bush, Eddie M K Chung, Stylianos E Antonarakis, Michael R Loebinger, Robert Wilson, Miguel Armengot, Estelle Escudier, Claire Hogg, Serge Amselem, Zhaoxia Sun, Lucia Bartoloni, Jean-Louis Blouin, Hannah M Mitchison
By moving essential body fluids and molecules, motile cilia and flagella govern respiratory mucociliary clearance, laterality determination and the transport of gametes and cerebrospinal fluid. Primary ciliary dyskinesia (PCD) is an autosomal recessive disorder frequently caused by non-assembly of dynein arm motors into cilia and flagella axonemes. Before their import into cilia and flagella, multi-subunit axonemal dynein arms are thought to be stabilized and pre-assembled in the cytoplasm through a DNAAF2-DNAAF4-HSP90 complex akin to the HSP90 co-chaperone R2TP complex...
February 8, 2017: Nature Communications
https://www.readbyqxmd.com/read/28170030/toward-optical-guidance-during-endoscopic-ultrasound-guided-fine-needle-aspirations-of-pancreatic-masses-using-single-fiber-reflectance-spectroscopy-a-feasibility-study
#18
Paulien L Stegehuis, Leonora S F Boogerd, Akin Inderson, Roeland A Veenendaal, P van Gerven, Bert A Bonsing, J Sven Mieog, Arjen Amelink, Maud Veselic, Hans Morreau, Cornelis J H van de Velde, Boudewijn P F Lelieveldt, Jouke Dijkstra, Dominic J Robinson, Alexander L Vahrmeijer
No abstract text is available yet for this article.
February 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28167674/ventrolateral-striatal-medium-spiny-neurons-positively-regulate-food-incentive-goal-directed-behavior-independently-of-d1-and-d2-selectivity
#19
Akiyo Natsubori, Iku Tsustui-Kimura, Hiroshi Nishida, Youcef Bouchekioua, Hiroshi Sekiya, Motokazu Uchigashima, Masahiko Watanabe, Alban de Kerchove d'Exaerde, Masaru Mimura, Norio Takata, Kenji F Tanaka
: The ventral striatum is involved in motivated behavior. Akin to the dorsal striatum, the ventral striatum contains two parallel pathways: the striatomesencephalic pathway consisting of dopamine receptor type 1-expressing medium spiny neurons (D1-MSNs) and the striatopallidal pathway consisting of D2-MSNs. These two genetically identified pathways are thought to encode opposing functions in motivated behavior. It has also been reported that D1/D2 genetic selectivity is not attributed to the anatomical discrimination of two pathways...
February 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28164062/case-report-of-mimicry-between-synovial-hemangioma-and-synovial-chondromatosis-of-the-shoulder
#20
Justin Colanese, Akin Cil, Nkem Egekeze, Kamani Lankachandra, Suhel Kotwal
INTRODUCTION: Synovial hemangioma is a developmental hamartoma of vascular tissue within the synovium; no cases involving the shoulder girdle have been described in the literature. Synovial chondromatosis is a benign condition in which synovial cells undergo metaplasia into hyaline cartilage and is also thought to infrequently affect the shoulder region. CASE REPORT: A 44-year-old female presented with left shoulder pain of 7-year duration. Magnetic resonance image displayed a 2...
September 2016: Journal of Orthopaedic Case Reports
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