keyword
https://read.qxmd.com/read/38091276/a-28-year-old-woman-with-down-syndrome-congenital-heart-disease-and-a-history-of-knee-surgery-and-plantar-fasciitis-with-hallux-abducto-valgus-bunion-and-lapiplasty-three-dimensional-correction-surgery
#21
JOURNAL ARTICLE
Eduardo Simón-Pérez, Rodrigo Jiménez-Martín, Luke D Cicchinelli, Javier Fernández Yagüe, Clarisa Simón-Pérez, Joaquin Paez-Moguer, Antonio Cortés-Rodríguez, Alejandro Castillo-Domínguez
BACKGROUND Tarsometatarsal joint (TMJ) arthrodesis is common method used for correcting hallux abductus valgus (HAV). Its popularity has grown due to studies revealing HAV's triplanar deformity with frontal plane rotation. This case report presents a 28-year-old woman with Down syndrome, congenital heart disease, and a history of knee surgery and plantar fasciitis, with severe HAV deformity and flexible valgus flatfoot associated with ligamentous hyperlaxity. CASE REPORT Examination revealed severe foot deformities, and radiographic studies confirmed the condition...
December 13, 2023: American Journal of Case Reports
https://read.qxmd.com/read/38077069/loss-of-slc35a2-alters-development-of-the-mouse-cerebral-cortex
#22
Soad Elziny, Sahibjot Sran, Hyojung Yoon, Rachel R Corrigan, John Page, Amanda Ringland, Anna Lanier, Sara Lapidus, James Foreman, Erin L Heinzen, Philip Iffland, Peter B Crino, Tracy A Bedrosian
Brain somatic variants in SLC35A2 are associated with clinically drug-resistant epilepsy and developmental brain malformations, including mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE). SLC35A2 encodes a uridine diphosphate galactose translocator that is essential for protein glycosylation; however, the neurodevelopmental mechanisms by which SLC35A2 disruption leads to clinical and histopathological features remain unspecified. We hypothesized that focal knockout (KO) or knockdown (KD) of Slc35a2 in the developing mouse cortex would disrupt cerebral cortical development through altered neuronal migration and cause changes in network excitability...
November 30, 2023: bioRxiv
https://read.qxmd.com/read/38057541/analysis-of-rhizosphere-fungal-community-of-agricultural-crops-cultivated-in-laboratory-experiments-on-chernevaya-taiga-soil
#23
JOURNAL ARTICLE
Irina Kravchenko, Mikhail Rayko, Sophie Sokornova, Ekaterina Tikhonova, Aleksey Konopkin, Alla Lapidus
Chernevaya taiga of Western Siberia, Russia, is a unique ecosystem characterized by fertile soil, exceptionally large herbaceous plant sizes, and extraordinarily rapid rates of plant residue degradation. We expected that growing crops on soil collected from Chernevaya taiga, which has never been used for agricultural purposes before, would result in a distinct rhizospheric fungal community. This community could potentially yield novel, potent biostimulators and biocontrol fungi for modern agriculture. To check this idea, we used high-throughput ITS sequencing to examine the microbial communities in the rhizosphere of spring wheat and radish grown in greenhouse experiments on Chernevaya and control soils...
December 7, 2023: World Journal of Microbiology & Biotechnology
https://read.qxmd.com/read/38027299/corrigendum-increase-in-pediatric-recurrent-fever-evaluations-during-the-first-year-of-the-covid-19-pandemic-in-north-america
#24
Leanne M Mansfield, Sivia K Lapidus, Samira Nazzar Romero, Lakshmi N Moorthy, Felice C Adler-Shohet, Matthew Hollander, Julie Cherian, Marinka Twilt, Geraldina Lionetti, Smriti Mohan, Patricia A DeLaMora, Karen L Durrant, Theresa Wampler Muskardin, Mariana Correia Marques, Karen B Onel, Fatma Dedeoglu, Maria J Gutierrez, Grant Schulert
[This corrects the article DOI: 10.3389/fped.2023.1240242.].
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/38012377/author-correction-lifespan-extending-interventions-induce-consistent-patterns-of-fatty-acid-oxidation-in-mouse-livers
#25
Kengo Watanabe, Tomasz Wilmanski, Priyanka Baloni, Max Robinson, Gonzalo G Garcia, Michael R Hoopmann, Mukul K Midha, David H Baxter, Michal Maes, Seamus R Morrone, Kelly M Crebs, Charu Kapil, Ulrike Kusebauch, Jack Wiedrick, Jodi Lapidus, Lance Pflieger, Christopher Lausted, Jared C Roach, Gwênlyn Glusman, Steven R Cummings, Nicholas J Schork, Nathan D Price, Leroy Hood, Richard A Miller, Robert L Moritz, Noa Rappaport
No abstract text is available yet for this article.
November 27, 2023: Communications Biology
https://read.qxmd.com/read/37996427/stabilizing-lattice-oxygen-redox-in-layered-sodium-transition-metal-oxide-through-spin-singlet-state
#26
JOURNAL ARTICLE
Xuelong Wang, Liang Yin, Arthur Ronne, Yiman Zhang, Zilin Hu, Sha Tan, Qinchao Wang, Bohang Song, Mengya Li, Xiaohui Rong, Saul Lapidus, Shize Yang, Enyuan Hu, Jue Liu
Reversible lattice oxygen redox reactions offer the potential to enhance energy density and lower battery cathode costs. However, their widespread adoption faces obstacles like substantial voltage hysteresis and poor stability. The current research addresses these challenges by achieving a non-hysteresis, long-term stable oxygen redox reaction in the P3-type Na2/3 Cu1/3 Mn2/3 O2 . Here we show this is accomplished by forming spin singlet states during charge and discharge. Detailed analysis, including in-situ X-ray diffraction, shows highly reversible structural changes during cycling...
November 23, 2023: Nature Communications
https://read.qxmd.com/read/37983308/irge-4-a-predicted-weyl-metal-with-a-chiral-crystal-structure
#27
JOURNAL ARTICLE
Callista M Skaggs, Dong-Choon Ryu, Hari Bhandari, Yan Xin, Chang-Jong Kang, Saul H Lapidus, Peter E Siegfried, Nirmal J Ghimire, Xiaoyan Tan
Polycrystalline IrGe4 was synthesized by annealing elements at 800 °C for 240 h, and the composition was confirmed by energy-dispersive X-ray spectroscopy. IrGe4 adopts a chiral crystal structure (space group P 31 21) instead of a polar crystal structure ( P 31 ), which was corroborated by the convergent-beam electron diffraction and Rietveld refinements using synchrotron powder X-ray diffraction data. The crystal structure features layers of IrGe8 polyhedra along the b axis, and the layers are connected by edge- and corner-sharing...
November 20, 2023: Inorganic Chemistry
https://read.qxmd.com/read/37964442/open-vs-minimally-invasive-resection-of-the-first-metatarsocuneiform-joint-an-anatomical-study
#28
JOURNAL ARTICLE
Sebastian Schilde, Dariusch Arbab, Maria Felsberg, Heike Kielstein, Karl-Stefan Delank, Natalia Gutteck
BACKGROUND: The modified Lapidus arthrodesis is a standard procedure to correct middle to severe hallux valgus (HV) deformities. Recently, minimally invasive techniques of first metatarsocuneiform joint (MCJ) resection using a Shannon burr were described. The primary goal of this study is to compare the anatomical efficacy and safety of first MCJ resection using a straight 2 × 13-mm Shannon burr and minimally invasive technique (MIS) vs an open technique using an oscillating saw...
December 2023: Foot & Ankle International
https://read.qxmd.com/read/37951679/early-functional-rehabilitation-in-foot-and-ankle-surgery
#29
REVIEW
Sandeep Patel, Shontal Behan Dionisopoulos, Monte Jay Schmalhaus
The traditional postoperative management of common foot and ankle procedures has involved a prolonged period of immobilization and nonweight bearing. The concern was loss of correction and fixation failure. However, it has been shown that a prolonged period of nonweight bearing can predispose patients possible deep vein thrombosis, disuse osteopenia, cardiovascular complications, and generalized deconditioning. The authors' institution has published studies reviewing the efficacy of early weight bearing after first metatarsophalangeal joint arthrodesis, modified Lapidus bunionectomy, and open reduction and internal fixation of ankle fractures...
January 2024: Clinics in Podiatric Medicine and Surgery
https://read.qxmd.com/read/37951678/the-lapidus-bunionectomy-revolution-current-concepts-and-considerations
#30
REVIEW
Christy M King, Francesca M Castellucci-Garza
Hallux valgus is a common foot deformity in which many surgical techniques have been introduced. Originally, Paul Lapidus detailed a midfoot arthrodesis technique to address the deformity and medial column instability that served as the foundation for the modified Lapidus bunionectomy. The appreciation of the multiplanar nature of hallux valgus deformity continues to evolve and helps to guide the investigation of the ideal surgical correction to yield more predictable results and reduced complications. Various fixation constructs have been used over the years for the Lapidus bunionectomy without a clear superior fixation technique, and literature supports early weight-bearing with each...
January 2024: Clinics in Podiatric Medicine and Surgery
https://read.qxmd.com/read/37942098/modified-endoscopic-distal-soft-tissue-procedure-medstp-and-arthroscopic-lapidus-arthrodesis-for-correction-of-severe-hallux-valgus
#31
JOURNAL ARTICLE
Tun Hing Lui, Charles Churk Hang Li, Sui Kit Chan, Amanda Mun Yee Slocum
Hallux valgus is one of the most common forefoot deformities faced by foot and ankle surgeons. Symptomatic deformity usually needs surgical correction. Endoscopic techniques of hallux valgus correction have been reported that are based on the same principle of the classic distal soft tissue procedure. Recently, the technique has been modified to include reconstruction of the medial metatarsosesamoid ligament and augmentation of the intermetatarsal ligament. In severe deformity or the presence of hypermobility or painful degeneration of the first tarsometatarsal joint, Lapidus arthrodesis of the joint is indicated...
October 2023: Arthroscopy Techniques
https://read.qxmd.com/read/37910598/knee-disarticulation-vs-transfemoral-amputation-after-failed-transtibial-amputation-surgical-outcome-and-prosthetic-fitting-in-patients-with-peripheral-vascular-disease
#32
JOURNAL ARTICLE
Lina S Sjödin, Carin C Ottosson, Lasse J Lapidus
OBJECTIVE: Our aim was to compare transfemoral amputation (TFA) to knee disarticulation (KD) as a reamputation level after failed transtibial amputation (TTA) in patients with peripheral vascular disease and/or diabetes. METHODS: We studied 152 patients undergoing reamputation, 86 TFA and 66 KD, after a failed TTA. The primary outcome was reamputation and reoperation, and secondary outcomes were prosthetic fitting and mortality. Logistic regression analyses were performed to identify factors associated with the outcome...
November 1, 2023: Prosthetics and Orthotics International
https://read.qxmd.com/read/37898317/direct-and-indirect-impact-of-the-covid-19-pandemic-on-the-survival-of-kidney-transplant-recipients-a-national-observational-study-in-france
#33
JOURNAL ARTICLE
Elhadji Leye, Tristan Delory, Khalil El Karoui, Maude Espagnacq, Myriam Khlat, Sophie Le Coeur, Nathanaël Lapidus, Gilles Hejblum
During the pandemic period, health care systems were substantially reorganized for managing COVID-19 cases. Corresponding consequences on persons with chronic diseases remain insufficiently documented. This observational cohort study investigated the direct and indirect impact of the pandemic period on the survival of kidney transplant recipients (KTR). Using the French National Health Data System, incident persons with end-stage kidney disease between 2015 and 2020, and who received a kidney transplant during this period were included and followed up from their transplantation date to December 31, 2021...
October 26, 2023: American Journal of Transplantation
https://read.qxmd.com/read/37875971/mobility-rehab-visual-feedback-system-for-gait-rehabilitation-in-older-adults
#34
JOURNAL ARTICLE
Carla Silva-Batista, Graham Harker, Rodrigo Vitorio, Mike Studer, Brady Whetten, Jodi Lapidus, Patricia Carlson-Kuhta, Sean Pearson, Jess VanDerwalker, Fay B Horak, Mahmoud El-Gohary, Martina Mancini
BACKGROUND: Gait and balance impairments are among the main causes of falls in older adults. The feasibility and effectiveness of adding sensor-based feedback to physical therapy (PT) in an outpatient PT setting is unknown. We evaluated the feasibility and effectiveness of PT intervention combined with a therapist-assisted visual feedback system, called Mobility Rehab, (PT + MR) in older adults. METHODS: Twenty-eight older adults with and without neurological diseases were assigned either PT + MR (n = 22) or PT alone (n = 6)...
October 24, 2023: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/37865069/multiple-factors-contributing-to-the-metatarsal-head-eversion-in-hallux-valgus-deformity-a-prospective-study-using-weight-bearing-ct
#35
JOURNAL ARTICLE
Jill S Kawalec, Steven P Chambers, Riasat Ali, Lawrence S Osher
PURPOSE: Recently first tarsometatarsal arthrodesis for hallux abducto valgus (HAV) has been advocated as the sole procedure to correct the multiplanar components of the deformity. However, recent debate suggests other factors such as rearfoot pronation and metatarsal torsion affect frontal plane metatarsal eversion and sesamoid positioning. Using weight-bearing CT, 12 feet (12 subjects) with HAV deformities were placed in positions of maximum rearfoot pronation and supination in order to study the effects on metatarsal eversion, sesamoid rotation/displacement, and secondarily the influence of first metatarsal torsion...
February 2, 2023: Foot
https://read.qxmd.com/read/37846094/changes-in-radiographic-alignment-following-metatarsophalangeal-fusion-distal-metatarsal-osteotomy-and-lapidus
#36
JOURNAL ARTICLE
Timothy Dusch, Alexander Guareschi, Andrew Moore, Caroline Hoch, Christopher E Gross, Daniel J Scott
BACKGROUND: The purpose of this study is to evaluate the effect of the different surgical treatments for hallux valgus on various radiographic measures of bunion correction. METHODS: A retrospective cohort study was conducted at a single academic medical center involving 2 fellowship-trained foot and ankle surgeons. One hundred and nineteen feet (110 patients) were included. Procedures included first metatarsophalangeal (MTP) arthrodesis (n = 88), Chevron and/or Scarf osteotomy (n = 23), and Lapidus (n = 8)...
October 16, 2023: Foot & Ankle Specialist
https://read.qxmd.com/read/37786608/radiographic-and-patient-reported-outcomes-of-a-low-cost-modified-lapidus-bunion-correction-technique
#37
JOURNAL ARTICLE
Chinmay Shivaram Paranjape, Jingru Zhang, Trapper Lalli, Feng-Chang Lin, Joshua N Tennant
BACKGROUND: The modified Lapidus (ML) is a powerful procedure for correction of hallux valgus (HV) with emerging techniques. Studies considering patient-reported outcomes, radiographic measures, complications, and implant costs are currently limited. METHODS: Retrospective cohort with prospectively collected Patient Reported Outcome Information System Physical Function (PROMIS-PF) Computerized Adaptive Test (CAT) scores, radiographic parameters (intermetatarsal angle, IMA; hallux valgus angle, HVA; and tibial sesamoid position, TSP), complications, and total operative time and implant costs were reviewed from 2014 to 2019...
July 2023: Foot & ankle orthopaedics
https://read.qxmd.com/read/37725298/in-hospital-outcomes-after-acute-myocardial-infarction-with-obstructive-coronary-artery-disease-in-critically-ill-patients-hospitalized-for-non-cardiac-disease
#38
JOURNAL ARTICLE
Morgan Roué, Alexis F Guédon, Nathanaël Lapidus, Keyvan Razazi, Geoffroy Hariri, Elise Morawiec, Cyrielle Desnos, Stéphane Ederhy, Ariel Cohen, Armand Mekontso Dessap, Muriel Fartoukh, Vincent Labbé
BACKGROUND: Acute myocardial infarction (AMI) is one of the major cardiac complications in patients hospitalized in the intensive care unit (ICU) for non-cardiac disease. A better knowledge of ischemic and bleeding risks in these patients is needed to identify those most likely to benefit from specific cardiac management. We therefore assessed the incidence and predictors of a composite outcome of severe ischemic event (AMI recurrence, ischemic stroke), major bleeding, or all-cause death in this setting...
September 19, 2023: Annals of Intensive Care
https://read.qxmd.com/read/37676172/birth-mothers-experiences-of-support-before-during-and-after-adoptive-placement
#39
JOURNAL ARTICLE
Emily P Lapidus, Ciara L Watkins, Rachel H Farr
Birth mothers, or women who have relinquished parental rights of their child, are an understudied and stigmatized population. Prior literature has suggested that protective factors, such as supports (e.g., practical, emotional, peer, informational), are beneficial for birth mothers. This study qualitatively explored perceptions and experiences of support before, during, and after placement among 51 birth mothers whose children were adopted as infants via private adoption in the United States 8 months to 50 years ( M = 15...
September 7, 2023: American Journal of Orthopsychiatry
https://read.qxmd.com/read/37653270/proteomic-changes-induced-by-longevity-promoting-interventions-in-mice
#40
JOURNAL ARTICLE
Adam R Burns, Jack Wiedrick, Alicia Feryn, Michal Maes, Mukul K Midha, David H Baxter, Seamus R Morrone, Timothy J Prokop, Charu Kapil, Michael R Hoopmann, Ulrike Kusebauch, Eric W Deutsch, Noa Rappaport, Kengo Watanabe, Robert L Moritz, Richard A Miller, Jodi A Lapidus, Eric S Orwoll
Using mouse models and high-throughput proteomics, we conducted an in-depth analysis of the proteome changes induced in response to seven interventions known to increase mouse lifespan. This included two genetic mutations, a growth hormone receptor knockout (GHRKO mice) and a mutation in the Pit-1 locus (Snell dwarf mice), four drug treatments (rapamycin, acarbose, canagliflozin, and 17α-estradiol), and caloric restriction. Each of the interventions studied induced variable changes in the concentrations of proteins across liver, kidney, and gastrocnemius muscle tissue samples, with the strongest responses in the liver and limited concordance in protein responses across tissues...
August 31, 2023: GeroScience
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