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https://www.readbyqxmd.com/read/29119293/asparaginase-erwinia-chrysanthemi-effectively-depletes-plasma-glutamine-in-adult-patients-with-relapsed-refractory-acute-myeloid-leukemia
#1
Ashkan Emadi, Jennie Y Law, Erin T Strovel, Rena G Lapidus, Linda J B Jeng, Myounghee Lee, Miriam G Blitzer, Brandon A Carter-Cooper, Danielle Sewell, Isabella Van Der Merwe, Sunita Philip, Mohammad Imran, Stephen L Yu, Hongxia Li, Philip C Amrein, Vu H Duong, Edward A Sausville, Maria R Baer, Amir T Fathi, Zeba Singh, Søren M Bentzen
Depletion of glutamine (Gln) has emerged as a potential therapeutic approach in the treatment of acute myeloid leukemia (AML), as neoplastic cells require Gln for synthesis of cellular components essential for survival. Asparaginases deplete Gln, and asparaginase derived from Erwinia chrysanthemi (Erwinaze) appears to have the greatest glutaminase activity of the available asparaginases. In this Phase I study, we sought to determine the dose of Erwinaze that safely and effectively depletes plasma Gln levels to ≤ 120 μmol/L in patients with relapsed or refractory (R/R) AML...
November 8, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/29116457/correction-to-comparison-of-fracture-risk-assessment-tools-in-older-men-without-prior-hip-or-spine-fracture-the-mros-study
#2
Margaret L Gourlay, Victor S Ritter, Jason P Fine, Robert A Overman, John T Schousboe, Peggy M Cawthon, Eric S Orwoll, Tuan V Nguyen, Nancy E Lane, Steven R Cummings, Deborah M Kado, Jodi A Lapidus, Susan J Diem, Kristine E Ensrud
Owing to an oversight by the authors, the acknowledgments were incomplete.
November 7, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29112802/consensus-treatment-plans-for-chronic-nonbacterial-osteomyelitis-refractory-to-nonsteroidal-anti-inflammatory-drugs-and-or-with-active-spinal-lesions
#3
Yongdong Zhao, Eveline Y Wu, Melissa S Oliver, Ashley M Cooper, Matthew L Basiaga, Sheetal S Vora, Tzielan C Lee, Emily Fox, Gil Amarilyo, Sara M Stern, Jeffrey A Dvergsten, Kathleen A Haines, Kelly A Rouster-Stevens, Karen B Onel, Julie Cherian, Jonathan S Hausmann, Paivi Miettunen, Tania Cellucci, Farzana Nuruzzaman, Angela Taneja, Karyl S Barron, Matthew C Hollander, Sivia K Lapidus, Suzanne C Li, Seza Ozen, Hermann Girschick, Ronald M Laxer, Fatma Dedeoglu, Christian M Hedrich, Polly J Ferguson
OBJECTIVE: To develop standardized treatment regimens for chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO) to enable comparative effectiveness treatment studies. METHODS: Virtual and face-to-face discussions and meetings were held within the CNO subgroup of the Childhood Arthritis and Rheumatology Research Alliance (CARRA). A literature search was conducted, and CARRA membership was surveyed to evaluate available treatment data and identify current treatment practices...
November 7, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29103890/large-osseous-defect-reconstruction-using-a-custom-three-dimensional-printed-titanium-truss-implant
#4
Eric So, Vincent H Mandas, Lee Hlad
Treatment of large osseous defects remains a difficult surgical challenge. Autografts and allografts have been known to undergo late collapse, because these options are not specifically designed to withstand the high loads of the foot and ankle. The inability to achieve the correct shape for reconstruction further limits their application. Large osseous defects will result during salvage after failed Lapidus bunionectomy, explantation of failed total ankle replacements, and nonunion of Evans calcaneal osteotomy...
November 2, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29102357/effect-of-temperature-on-copper-iron-and-lead-leaching-from-e-waste-using-citrate-solutions
#5
Robinson Torres, Brenda Segura-Bailón, Gretchen T Lapidus
E-waste is a potential source of large quantities of metals. The ability of citrate solutions to recover base metals from these materials has been demonstrated. In the present study, the effect of the temperature on base metal leaching capacity by the citrate solutions is determined. The material employed consisted of a mechanically prepared, gravity concentrated e-waste, with a metallic content greater than 90%. The leaching conditions were selected based on previous research performed by the authors (0.5 M sodium citrate, pH 4...
October 25, 2017: Waste Management
https://www.readbyqxmd.com/read/29093768/draft-genome-sequence-of-marinobacterium-rhizophilum-cl-yj9-t-dsm-18822-t-isolated-from-the-rhizosphere-of-the-coastal-tidal-flat-plant-suaeda-japonica
#6
Dong Han Choi, Gwang Ii Jang, Alla Lapidus, Alex Copeland, T B K Reddy, Supratim Mukherjee, Marcel Huntemann, Neha Varghese, Natalia Ivanova, Manoj Pillay, Brian J Tindall, Markus Göker, Tanja Woyke, Hans-Peter Klenk, Nikos C Kyrpides, Byung Cheol Cho
The genus Marinobacterium belongs to the family Alteromonadaceae within the class Gammaproteobacteria and was reported in 1997. Currently the genus Marinobacterium contains 16 species. Marinobacterium rhizophilum CL-YJ9(T) was isolated from sediment associated with the roots of a plant growing in a tidal flat of Youngjong Island, Korea. The genome of the strain CL-YJ9(T) was sequenced through the Genomic Encyclopedia of Type Strains, Phase I: KMG project. Here we report the main features of the draft genome of the strain...
2017: Standards in Genomic Sciences
https://www.readbyqxmd.com/read/29091400/from-coating-to-dopant-how-the-transition-metal-composition-affects-alumina-coatings-on-ni-rich-cathodes
#7
Binghong Han, Baris Key, Saul H Lapidus, Juan C Garcia, Hakim Iddir, John T Vaughey, Fulya Dogan
Surface alumina coatings have been shown to be an effective way to improve the stability and cyclability of cathode materials. However, a detailed understanding of the relationship between the surface coatings and the bulk layered oxides is needed to better define the critical cathode-electrolyte interface. In this paper, we systematically studied the effect of the composition of Ni-rich LiNixMnyCo1-x-yO2 (NMC) on the surface alumina coatings. Changing cathode composition from LiNi0.5Mn0.3Co0.2O2 (NMC532) to LiNi0...
November 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29074603/concurrent-inhibition-of-pim-and-flt3-kinases-enhances-apoptosis-of-flt3-itd-acute-myeloid-leukemia-cells-through-increased-mcl-1-proteasomal-degradation
#8
Shivani Kapoor, Karthika Natarajan, Patrick R Baldwin, Kshama A Doshi, Rena G Lapidus, Trevor J Mathias, Mario Scarpa, Rossana Trotta, Eduardo Davila, Manfred Kraus, Dennis Huszar, Adriana E Tron, Danilo Perrotti, Maria R Baer
PURPOSE: fms-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) is present in 30% of acute myeloid leukemia (AML), and these patients have short disease-free survival. FLT3 inhibitors have limited and transient clinical activity, and concurrent treatment with inhibitors of parallel or downstream signaling may improve responses. The oncogenic serine/threonine kinase Pim-1 is upregulated downstream of FLT3-ITD and also promotes its signaling in a positive feedback loop, suggesting benefit of combined Pim and FLT3 inhibition...
October 26, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29059434/breaking-mitochondrial-fasting-for-cancer-treatment-old-wine-in-new-bottles
#9
Ashkan Emadi, Rena G Lapidus
No abstract text is available yet for this article.
November 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29052793/comparison-of-fracture-risk-assessment-tools-in-older-men-without-prior-hip-or-spine-fracture-the-mros-study
#10
Margaret L Gourlay, Victor S Ritter, Jason P Fine, Robert A Overman, John T Schousboe, Peggy M Cawthon, Eric S Orwoll, Tuan V Nguyen, Nancy E Lane, Steven R Cummings, Deborah M Kado, Jodi A Lapidus, Susan J Diem, Kristine E Ensrud
Femoral neck bone mineral density (BMD), age plus femoral neck BMD T score, and three externally generated fracture risk tools had similar accuracy to identify older men who developed osteoporotic fractures. Risk tools with femoral neck BMD performed better than those without BMD. The externally developed risk tools were poorly calibrated. INTRODUCTION: We compared the performance of fracture risk assessment tools in older men, accounting for competing risks including mortality. METHODS: A comparative ROC curve analysis assessed the ability of the QFracture, FRAX® and Garvan fracture risk tools, and femoral neck bone mineral density (BMD) T score with or without age to identify incident fracture in community-dwelling men aged 65 years or older (N = 4994) without hip or clinical vertebral fracture or antifracture treatment at baseline...
October 20, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29050333/characterization-of-cadd522-a-small-molecule-that-inhibits-runx2-dna-binding-and-exhibits-antitumor-activity
#11
Myoung Sook Kim, Ramkishore Gernapudi, Eun Yong Choi, Rena G Lapidus, Antonino Passaniti
The RUNX2 transcription factor promotes breast cancer growth and metastasis through interactions with a variety of cofactors that activate or repress target genes. Using a direct drug discovery approach we identified CADD522 as a small molecule that inhibits the DNA binding of the runt box domain protein, RUNX2. The current study defines the effect of CADD522 on breast cancer growth and metastasis, and addresses the mechanisms by which it exerts its anti-tumor activity. CADD522 treatment resulted in significant growth inhibition, clonogenic survival, tumorsphere formation, and invasion of breast cancer cells...
September 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29034084/protein-unfolding-mechanisms-and-their-effects-on-folding-experiments
#12
REVIEW
Lisa J Lapidus
In this review, I discuss the various methods researchers use to unfold proteins in the lab in order to understand protein folding both in vitro and in vivo. The four main techniques, chemical-, heat-, pressure- and force-denaturation, produce distinctly different unfolded conformational ensembles. Recent measurements have revealed different folding kinetics from different unfolding mechanisms. Thus, comparing these distinct unfolded ensembles sheds light on the underlying free energy landscape of folding.
2017: F1000Research
https://www.readbyqxmd.com/read/29023648/improvements-in-hospice-utilization-among-patients-with-advanced-stage-lung-cancer-in-an-integrated-health-care-system
#13
Donald R Sullivan, Linda Ganzini, Jodi A Lapidus, Lissi Hansen, Patricia A Carney, Molly L Osborne, Erik K Fromme, Seiko Izumi, Christopher G Slatore
BACKGROUND: Hospice, a patient-centered care system for those with limited life expectancy, is important for enhancing quality of life and is understudied in integrated health care systems. METHODS: This was a retrospective cohort study of 21,860 decedents with advanced-stage lung cancer diagnosed from January 2007 to June 2013 in the national US Veterans Affairs Health Care System. Trends over time, geographic regional variability, and patient and tumor characteristics associated with hospice use and the timing of enrollment were examined...
October 10, 2017: Cancer
https://www.readbyqxmd.com/read/28956220/establishing-the-prevalence-of-intimate-partner-violence-among-hair-salon-clients
#14
Rebecca F Beebe, Susan C DiVietro, Maureen Dunn, Kathryn Bentivegna, Meghan E Clough, Garry D Lapidus, D'Andrea K Joseph
This study determined prevalence of intimate partner violence (IPV) victimization among female clients at three hair salons in Connecticut using an anonymous tablet based screening tool. While many may assume that women receive services at hair salons, victims of IPV are often isolated by their partners and unable to access help. Of the 203 clients who participated, 40 (20%) had experienced IPV in her lifetime. In identifying the prevalence of IPV within the salon setting, this study provides support for community-based programs and supports their legitimacy as an important locus for identifying women experiencing IPV and connecting them to resources...
September 27, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28949169/anomalous-evolution-of-the-near-side-jet-peak-shape-in-pb-pb-collisions-at-sqrt-s_-nn-2-76%C3%A2-%C3%A2-tev
#15
J Adam, D Adamová, M M Aggarwal, G Aglieri Rinella, M Agnello, N Agrawal, Z Ahammed, S Ahmad, S U Ahn, S Aiola, A Akindinov, S N Alam, D S D Albuquerque, D Aleksandrov, B Alessandro, D Alexandre, R Alfaro Molina, A Alici, A Alkin, J Alme, T Alt, S Altinpinar, I Altsybeev, C Alves Garcia Prado, M An, C Andrei, H A Andrews, A Andronic, V Anguelov, C Anson, T Antičić, F Antinori, P Antonioli, R Anwar, L Aphecetche, H Appelshäuser, S Arcelli, R Arnaldi, O W Arnold, I C Arsene, M Arslandok, B Audurier, A Augustinus, R Averbeck, M D Azmi, A Badalà, Y W Baek, S Bagnasco, R Bailhache, R Bala, S Balasubramanian, A Baldisseri, R C Baral, A M Barbano, R Barbera, F Barile, G G Barnaföldi, L S Barnby, V Barret, P Bartalini, K Barth, J Bartke, E Bartsch, M Basile, N Bastid, S Basu, B Bathen, G Batigne, A Batista Camejo, B Batyunya, P C Batzing, I G Bearden, H Beck, C Bedda, N K Behera, I Belikov, F Bellini, H Bello Martinez, R Bellwied, L G E Beltran, V Belyaev, G Bencedi, S Beole, A Bercuci, Y Berdnikov, D Berenyi, R A Bertens, D Berzano, L Betev, A Bhasin, I R Bhat, A K Bhati, B Bhattacharjee, J Bhom, L Bianchi, N Bianchi, C Bianchin, J Bielčík, J Bielčíková, A Bilandzic, G Biro, R Biswas, S Biswas, S Bjelogrlic, J T Blair, D Blau, C Blume, F Bock, A Bogdanov, L Boldizsár, M Bombara, M Bonora, J Book, H Borel, A Borissov, M Borri, E Botta, C Bourjau, P Braun-Munzinger, M Bregant, T A Broker, T A Browning, M Broz, E J Brucken, E Bruna, G E Bruno, D Budnikov, H Buesching, S Bufalino, P Buhler, S A I Buitron, P Buncic, O Busch, Z Buthelezi, J B Butt, J T Buxton, J Cabala, D Caffarri, H Caines, A Caliva, E Calvo Villar, P Camerini, F Carena, W Carena, F Carnesecchi, J Castillo Castellanos, A J Castro, E A R Casula, C Ceballos Sanchez, J Cepila, P Cerello, J Cerkala, B Chang, S Chapeland, M Chartier, J L Charvet, S Chattopadhyay, S Chattopadhyay, A Chauvin, V Chelnokov, M Cherney, C Cheshkov, B Cheynis, V Chibante Barroso, D D Chinellato, S Cho, P Chochula, K Choi, M Chojnacki, S Choudhury, P Christakoglou, C H Christensen, P Christiansen, T Chujo, S U Chung, C Cicalo, L Cifarelli, F Cindolo, J Cleymans, F Colamaria, D Colella, A Collu, M Colocci, G Conesa Balbastre, Z Conesa Del Valle, M E Connors, J G Contreras, T M Cormier, Y Corrales Morales, I Cortés Maldonado, P Cortese, M R Cosentino, F Costa, J Crkovská, P Crochet, R Cruz Albino, E Cuautle, L Cunqueiro, T Dahms, A Dainese, M C Danisch, A Danu, D Das, I Das, S Das, A Dash, S Dash, S De, A De Caro, G de Cataldo, C de Conti, J de Cuveland, A De Falco, D De Gruttola, N De Marco, S De Pasquale, R D De Souza, A Deisting, A Deloff, C Deplano, P Dhankher, D Di Bari, A Di Mauro, P Di Nezza, B Di Ruzza, M A Diaz Corchero, T Dietel, P Dillenseger, R Divià, Ø Djuvsland, A Dobrin, D Domenicis Gimenez, B Dönigus, O Dordic, T Drozhzhova, A K Dubey, A Dubla, L Ducroux, A K Duggal, P Dupieux, R J Ehlers, D Elia, E Endress, H Engel, E Epple, B Erazmus, F Erhardt, B Espagnon, S Esumi, G Eulisse, J Eum, D Evans, S Evdokimov, G Eyyubova, L Fabbietti, D Fabris, J Faivre, A Fantoni, M Fasel, L Feldkamp, A Feliciello, G Feofilov, J Ferencei, A Fernández Téllez, E G Ferreiro, A Ferretti, A Festanti, V J G Feuillard, J Figiel, M A S Figueredo, S Filchagin, D Finogeev, F M Fionda, E M Fiore, M Floris, S Foertsch, P Foka, S Fokin, E Fragiacomo, A Francescon, A Francisco, U Frankenfeld, G G Fronze, U Fuchs, C Furget, A Furs, M Fusco Girard, J J Gaardhøje, M Gagliardi, A M Gago, K Gajdosova, M Gallio, C D Galvan, D R Gangadharan, P Ganoti, C Gao, C Garabatos, E Garcia-Solis, K Garg, P Garg, C Gargiulo, P Gasik, E F Gauger, M B Gay Ducati, M Germain, P Ghosh, S K Ghosh, P Gianotti, P Giubellino, P Giubilato, E Gladysz-Dziadus, P Glässel, D M Goméz Coral, A Gomez Ramirez, A S Gonzalez, V Gonzalez, P González-Zamora, S Gorbunov, L Görlich, S Gotovac, V Grabski, L K Graczykowski, K L Graham, L Greiner, A Grelli, C Grigoras, V Grigoriev, A Grigoryan, S Grigoryan, N Grion, J M Gronefeld, J F Grosse-Oetringhaus, R Grosso, L Gruber, F Guber, R Guernane, B Guerzoni, K Gulbrandsen, T Gunji, A Gupta, R Gupta, I B Guzman, R Haake, C Hadjidakis, H Hamagaki, G Hamar, J C Hamon, J W Harris, A Harton, D Hatzifotiadou, S Hayashi, S T Heckel, E Hellbär, H Helstrup, A Herghelegiu, G Herrera Corral, F Herrmann, B A Hess, K F Hetland, H Hillemanns, B Hippolyte, J Hladky, D Horak, R Hosokawa, P Hristov, C Hughes, T J Humanic, N Hussain, T Hussain, D Hutter, D S Hwang, R Ilkaev, M Inaba, M Ippolitov, M Irfan, V Isakov, M S Islam, M Ivanov, V Ivanov, V Izucheev, B Jacak, N Jacazio, P M Jacobs, M B Jadhav, S Jadlovska, J Jadlovsky, C Jahnke, M J Jakubowska, M A Janik, P H S Y Jayarathna, C Jena, S Jena, R T Jimenez Bustamante, P G Jones, A Jusko, P Kalinak, A Kalweit, J H Kang, V Kaplin, S Kar, A Karasu Uysal, O Karavichev, T Karavicheva, L Karayan, E Karpechev, U Kebschull, R Keidel, D L D Keijdener, M Keil, M Mohisin Khan, P Khan, S A Khan, A Khanzadeev, Y Kharlov, A Khatun, A Khuntia, B Kileng, D W Kim, D J Kim, D Kim, H Kim, J S Kim, J Kim, M Kim, M Kim, S Kim, T Kim, S Kirsch, I Kisel, S Kiselev, A Kisiel, G Kiss, J L Klay, C Klein, J Klein, C Klein-Bösing, S Klewin, A Kluge, M L Knichel, A G Knospe, C Kobdaj, M Kofarago, T Kollegger, A Kolojvari, V Kondratiev, N Kondratyeva, E Kondratyuk, A Konevskikh, M Kopcik, M Kour, C Kouzinopoulos, O Kovalenko, V Kovalenko, M Kowalski, G Koyithatta Meethaleveedu, I Králik, A Kravčáková, M Krivda, F Krizek, E Kryshen, M Krzewicki, A M Kubera, V Kučera, C Kuhn, P G Kuijer, A Kumar, J Kumar, L Kumar, S Kumar, S Kundu, P Kurashvili, A Kurepin, A B Kurepin, A Kuryakin, S Kushpil, M J Kweon, Y Kwon, S L La Pointe, P La Rocca, C Lagana Fernandes, I Lakomov, R Langoy, K Lapidus, C Lara, A Lardeux, A Lattuca, E Laudi, L Lazaridis, R Lea, L Leardini, S Lee, F Lehas, S Lehner, J Lehrbach, R C Lemmon, V Lenti, E Leogrande, I León Monzón, P Lévai, S Li, X Li, J Lien, R Lietava, S Lindal, V Lindenstruth, C Lippmann, M A Lisa, H M Ljunggren, W Llope, D F Lodato, P I Loenne, V Loginov, C Loizides, X Lopez, E López Torres, A Lowe, P Luettig, M Lunardon, G Luparello, M Lupi, T H Lutz, A Maevskaya, M Mager, S Mahajan, S M Mahmood, A Maire, R D Majka, M Malaev, I Maldonado Cervantes, L Malinina, D Mal'Kevich, P Malzacher, A Mamonov, V Manko, F Manso, V Manzari, Y Mao, M Marchisone, J Mareš, G V Margagliotti, A Margotti, J Margutti, A Marín, C Markert, M Marquard, N A Martin, P Martinengo, M I Martínez, G Martínez García, M Martinez Pedreira, A Mas, S Masciocchi, M Masera, A Masoni, A Mastroserio, A Matyja, C Mayer, J Mazer, M Mazzilli, M A Mazzoni, F Meddi, Y Melikyan, A Menchaca-Rocha, E Meninno, J Mercado Pérez, M Meres, S Mhlanga, Y Miake, M M Mieskolainen, K Mikhaylov, L Milano, J Milosevic, A Mischke, A N Mishra, T Mishra, D Miśkowiec, J Mitra, C M Mitu, N Mohammadi, B Mohanty, L Molnar, E Montes, D A Moreira De Godoy, L A P Moreno, S Moretto, A Morreale, A Morsch, V Muccifora, E Mudnic, D Mühlheim, S Muhuri, M Mukherjee, J D Mulligan, M G Munhoz, K Münning, R H Munzer, H Murakami, S Murray, L Musa, J Musinsky, C J Myers, B Naik, R Nair, B K Nandi, R Nania, E Nappi, M U Naru, H Natal da Luz, C Nattrass, S R Navarro, K Nayak, R Nayak, T K Nayak, S Nazarenko, A Nedosekin, R A Negrao De Oliveira, L Nellen, F Ng, M Nicassio, M Niculescu, J Niedziela, B S Nielsen, S Nikolaev, S Nikulin, V Nikulin, F Noferini, P Nomokonov, G Nooren, J C C Noris, J Norman, A Nyanin, J Nystrand, H Oeschler, S Oh, A Ohlson, T Okubo, L Olah, J Oleniacz, A C Oliveira Da Silva, M H Oliver, J Onderwaater, C Oppedisano, R Orava, M Oravec, A Ortiz Velasquez, A Oskarsson, J Otwinowski, K Oyama, M Ozdemir, Y Pachmayer, V Pacik, D Pagano, P Pagano, G Paić, S K Pal, P Palni, J Pan, A K Pandey, V Papikyan, G S Pappalardo, P Pareek, J Park, W J Park, S Parmar, A Passfeld, V Paticchio, R N Patra, B Paul, H Pei, T Peitzmann, X Peng, H Pereira Da Costa, D Peresunko, E Perez Lezama, V Peskov, Y Pestov, V Petráček, V Petrov, M Petrovici, C Petta, S Piano, M Pikna, P Pillot, L O D L Pimentel, O Pinazza, L Pinsky, D B Piyarathna, M Płoskoń, M Planinic, J Pluta, S Pochybova, P L M Podesta-Lerma, M G Poghosyan, B Polichtchouk, N Poljak, W Poonsawat, A Pop, H Poppenborg, S Porteboeuf-Houssais, J Porter, J Pospisil, S K Prasad, R Preghenella, F Prino, C A Pruneau, I Pshenichnov, M Puccio, G Puddu, P Pujahari, V Punin, J Putschke, H Qvigstad, A Rachevski, S Raha, S Rajput, J Rak, A Rakotozafindrabe, L Ramello, F Rami, D B Rana, R Raniwala, S Raniwala, S S Räsänen, B T Rascanu, D Rathee, V Ratza, I Ravasenga, K F Read, K Redlich, A Rehman, P Reichelt, F Reidt, X Ren, R Renfordt, A R Reolon, A Reshetin, K Reygers, V Riabov, R A Ricci, T Richert, M Richter, P Riedler, W Riegler, F Riggi, C Ristea, M Rodríguez Cahuantzi, K Røed, E Rogochaya, D Rohr, D Röhrich, F Ronchetti, L Ronflette, P Rosnet, A Rossi, F Roukoutakis, A Roy, C Roy, P Roy, A J Rubio Montero, R Rui, R Russo, E Ryabinkin, Y Ryabov, A Rybicki, S Saarinen, S Sadhu, S Sadovsky, K Šafařík, B Sahlmuller, B Sahoo, P Sahoo, R Sahoo, S Sahoo, P K Sahu, J Saini, S Sakai, M A Saleh, J Salzwedel, S Sambyal, V Samsonov, A Sandoval, M Sano, D Sarkar, N Sarkar, P Sarma, M H P Sas, E Scapparone, F Scarlassara, R P Scharenberg, C Schiaua, R Schicker, C Schmidt, H R Schmidt, M Schmidt, J Schukraft, Y Schutz, K Schwarz, K Schweda, G Scioli, E Scomparin, R Scott, M Šefčík, J E Seger, Y Sekiguchi, D Sekihata, I Selyuzhenkov, K Senosi, S Senyukov, E Serradilla, P Sett, A Sevcenco, A Shabanov, A Shabetai, O Shadura, R Shahoyan, A Shangaraev, A Sharma, A Sharma, M Sharma, M Sharma, N Sharma, A I Sheikh, K Shigaki, Q Shou, K Shtejer, Y Sibiriak, S Siddhanta, K M Sielewicz, T Siemiarczuk, D Silvermyr, C Silvestre, G Simatovic, G Simonetti, R Singaraju, R Singh, V Singhal, T Sinha, B Sitar, M Sitta, T B Skaali, M Slupecki, N Smirnov, R J M Snellings, T W Snellman, J Song, M Song, Z Song, F Soramel, S Sorensen, F Sozzi, E Spiriti, I Sputowska, B K Srivastava, J Stachel, I Stan, P Stankus, E Stenlund, G Steyn, J H Stiller, D Stocco, P Strmen, A A P Suaide, T Sugitate, C Suire, M Suleymanov, M Suljic, R Sultanov, M Šumbera, S Sumowidagdo, K Suzuki, S Swain, A Szabo, I Szarka, A Szczepankiewicz, M Szymanski, U Tabassam, J Takahashi, G J Tambave, N Tanaka, M Tarhini, M Tariq, M G Tarzila, A Tauro, G Tejeda Muñoz, A Telesca, K Terasaki, C Terrevoli, B Teyssier, D Thakur, D Thomas, R Tieulent, A Tikhonov, A R Timmins, A Toia, S Tripathy, S Trogolo, G Trombetta, V Trubnikov, W H Trzaska, T Tsuji, A Tumkin, R Turrisi, T S Tveter, K Ullaland, E N Umaka, A Uras, G L Usai, A Utrobicic, M Vala, J Van Der Maarel, J W Van Hoorne, M van Leeuwen, T Vanat, P Vande Vyvre, D Varga, A Vargas, M Vargyas, R Varma, M Vasileiou, A Vasiliev, A Vauthier, O Vázquez Doce, V Vechernin, A M Veen, A Velure, E Vercellin, S Vergara Limón, R Vernet, R Vértesi, L Vickovic, S Vigolo, J Viinikainen, Z Vilakazi, O Villalobos Baillie, A Villatoro Tello, A Vinogradov, L Vinogradov, T Virgili, V Vislavicius, A Vodopyanov, M A Völkl, K Voloshin, S A Voloshin, G Volpe, B von Haller, I Vorobyev, D Voscek, D Vranic, J Vrláková, B Wagner, J Wagner, H Wang, M Wang, D Watanabe, Y Watanabe, M Weber, S G Weber, D F Weiser, J P Wessels, U Westerhoff, A M Whitehead, J Wiechula, J Wikne, G Wilk, J Wilkinson, G A Willems, M C S Williams, B Windelband, M Winn, S Yalcin, P Yang, S Yano, Z Yin, H Yokoyama, I-K Yoo, J H Yoon, V Yurchenko, V Zaccolo, A Zaman, C Zampolli, H J C Zanoli, S Zaporozhets, N Zardoshti, A Zarochentsev, P Závada, N Zaviyalov, H Zbroszczyk, M Zhalov, H Zhang, X Zhang, Y Zhang, C Zhang, Z Zhang, C Zhao, N Zhigareva, D Zhou, Y Zhou, Z Zhou, H Zhu, J Zhu, A Zichichi, A Zimmermann, M B Zimmermann, G Zinovjev, J Zmeskal
The measurement of two-particle angular correlations is a powerful tool to study jet quenching in a p_{T} region inaccessible by direct jet identification. In these measurements pseudorapidity (Δη) and azimuthal (Δφ) differences are used to extract the shape of the near-side peak formed by particles associated with a higher p_{T} trigger particle (1<p_{T,trig}<8  GeV/c). A combined fit of the near-side peak and long-range correlations is applied to the data allowing the extraction of the centrality evolution of the peak shape in Pb-Pb collisions at sqrt[s_{NN}]=2...
September 8, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28943998/draft-genome-sequence-of-dethiobacter-alkaliphilus-strain-aht1-t-a-gram-positive-sulfidogenic-polyextremophile
#16
Emily Denise Melton, Dimitry Y Sorokin, Lex Overmars, Alla L Lapidus, Manoj Pillay, Natalia Ivanova, Tijana Glavina Del Rio, Nikos C Kyrpides, Tanja Woyke, Gerard Muyzer
Dethiobacter alkaliphilus strain AHT1(T) is an anaerobic, sulfidogenic, moderately salt-tolerant alkaliphilic chemolithotroph isolated from hypersaline soda lake sediments in northeastern Mongolia. It is a Gram-positive bacterium with low GC content, within the phylum Firmicutes. Here we report its draft genome sequence, which consists of 34 contigs with a total sequence length of 3.12 Mbp. D. alkaliphilus strain AHT1(T) was sequenced by the Joint Genome Institute (JGI) as part of the Community Science Program due to its relevance to bioremediation and biotechnological applications...
2017: Standards in Genomic Sciences
https://www.readbyqxmd.com/read/28943788/production-of-formula-see-text-and-formula-see-text-mesons-up-to-high-transverse-momentum-in-pp-collisions-at-2-76-tev
#17
S Acharya, D Adamová, M M Aggarwal, G Aglieri Rinella, M Agnello, N Agrawal, Z Ahammed, N Ahmad, S U Ahn, S Aiola, A Akindinov, S N Alam, D S D Albuquerque, D Aleksandrov, B Alessandro, D Alexandre, R Alfaro Molina, A Alici, A Alkin, J Alme, T Alt, I Altsybeev, C Alves Garcia Prado, M An, C Andrei, H A Andrews, A Andronic, V Anguelov, C Anson, T Antičić, F Antinori, P Antonioli, R Anwar, L Aphecetche, H Appelshäuser, S Arcelli, R Arnaldi, O W Arnold, I C Arsene, M Arslandok, B Audurier, A Augustinus, R Averbeck, T Awes, M D Azmi, A Badalà, Y W Baek, S Bagnasco, R Bailhache, R Bala, A Baldisseri, M Ball, R C Baral, A M Barbano, R Barbera, F Barile, L Barioglio, G G Barnaföldi, L S Barnby, V Barret, P Bartalini, K Barth, J Bartke, E Bartsch, M Basile, N Bastid, S Basu, B Bathen, G Batigne, A Batista Camejo, B Batyunya, P C Batzing, I G Bearden, H Beck, C Bedda, N K Behera, I Belikov, F Bellini, H Bello Martinez, R Bellwied, L G E Beltran, V Belyaev, G Bencedi, S Beole, A Bercuci, Y Berdnikov, D Berenyi, R A Bertens, D Berzano, L Betev, A Bhasin, I R Bhat, A K Bhati, B Bhattacharjee, J Bhom, L Bianchi, N Bianchi, C Bianchin, J Bielčík, J Bielčíková, A Bilandzic, G Biro, R Biswas, S Biswas, J T Blair, D Blau, C Blume, G Boca, F Bock, A Bogdanov, L Boldizsár, M Bombara, G Bonomi, M Bonora, J Book, H Borel, A Borissov, M Borri, E Botta, C Bourjau, P Braun-Munzinger, M Bregant, T A Broker, T A Browning, M Broz, E J Brucken, E Bruna, G E Bruno, D Budnikov, H Buesching, S Bufalino, P Buhler, S A I Buitron, P Buncic, O Busch, Z Buthelezi, J B Butt, J T Buxton, J Cabala, D Caffarri, H Caines, A Caliva, E Calvo Villar, P Camerini, A A Capon, F Carena, W Carena, F Carnesecchi, J Castillo Castellanos, A J Castro, E A R Casula, C Ceballos Sanchez, P Cerello, B Chang, S Chapeland, M Chartier, J L Charvet, S Chattopadhyay, S Chattopadhyay, A Chauvin, M Cherney, C Cheshkov, B Cheynis, V Chibante Barroso, D D Chinellato, S Cho, P Chochula, K Choi, M Chojnacki, S Choudhury, P Christakoglou, C H Christensen, P Christiansen, T Chujo, S U Chung, C Cicalo, L Cifarelli, F Cindolo, J Cleymans, F Colamaria, D Colella, A Collu, M Colocci, M Concas, G Conesa Balbastre, Z Conesa Del Valle, M E Connors, J G Contreras, T M Cormier, Y Corrales Morales, I Cortés Maldonado, P Cortese, M R Cosentino, F Costa, S Costanza, J Crkovská, P Crochet, E Cuautle, L Cunqueiro, T Dahms, A Dainese, M C Danisch, A Danu, D Das, I Das, S Das, A Dash, S Dash, S De, A De Caro, G de Cataldo, C de Conti, J de Cuveland, A De Falco, D De Gruttola, N De Marco, S De Pasquale, R D De Souza, H F Degenhardt, A Deisting, A Deloff, C Deplano, P Dhankher, D Di Bari, A Di Mauro, P Di Nezza, B Di Ruzza, M A Diaz Corchero, T Dietel, P Dillenseger, R Divià, Ø Djuvsland, A Dobrin, D Domenicis Gimenez, B Dönigus, O Dordic, T Drozhzhova, A K Dubey, A Dubla, L Ducroux, A K Duggal, P Dupieux, R J Ehlers, D Elia, E Endress, H Engel, E Epple, B Erazmus, F Erhardt, B Espagnon, S Esumi, G Eulisse, J Eum, D Evans, S Evdokimov, L Fabbietti, J Faivre, A Fantoni, M Fasel, L Feldkamp, A Feliciello, G Feofilov, J Ferencei, A Fernández Téllez, E G Ferreiro, A Ferretti, A Festanti, V J G Feuillard, J Figiel, M A S Figueredo, S Filchagin, D Finogeev, F M Fionda, E M Fiore, M Floris, S Foertsch, P Foka, S Fokin, E Fragiacomo, A Francescon, A Francisco, U Frankenfeld, G G Fronze, U Fuchs, C Furget, A Furs, M Fusco Girard, J J Gaardhøje, M Gagliardi, A M Gago, K Gajdosova, M Gallio, C D Galvan, P Ganoti, C Gao, C Garabatos, E Garcia-Solis, K Garg, P Garg, C Gargiulo, P Gasik, E F Gauger, M B Gay Ducati, M Germain, P Ghosh, S K Ghosh, P Gianotti, P Giubellino, P Giubilato, E Gladysz-Dziadus, P Glässel, D M Goméz Coral, A Gomez Ramirez, A S Gonzalez, V Gonzalez, P González-Zamora, S Gorbunov, L Görlich, S Gotovac, V Grabski, L K Graczykowski, K L Graham, L Greiner, A Grelli, C Grigoras, V Grigoriev, A Grigoryan, S Grigoryan, N Grion, J M Gronefeld, F Grosa, J F Grosse-Oetringhaus, R Grosso, L Gruber, F R Grull, F Guber, R Guernane, B Guerzoni, K Gulbrandsen, T Gunji, A Gupta, R Gupta, I B Guzman, R Haake, C Hadjidakis, H Hamagaki, G Hamar, J C Hamon, J W Harris, A Harton, D Hatzifotiadou, S Hayashi, S T Heckel, E Hellbär, H Helstrup, A Herghelegiu, G Herrera Corral, F Herrmann, B A Hess, K F Hetland, H Hillemanns, B Hippolyte, J Hladky, B Hohlweger, D Horak, S Hornung, R Hosokawa, P Hristov, C Hughes, T J Humanic, N Hussain, T Hussain, D Hutter, D S Hwang, R Ilkaev, M Inaba, M Ippolitov, M Irfan, V Isakov, M Ivanov, V Ivanov, V Izucheev, B Jacak, N Jacazio, P M Jacobs, M B Jadhav, S Jadlovska, J Jadlovsky, S Jaelani, C Jahnke, M J Jakubowska, M A Janik, P H S Y Jayarathna, C Jena, S Jena, M Jercic, R T Jimenez Bustamante, P G Jones, A Jusko, P Kalinak, A Kalweit, J Kamin, J H Kang, V Kaplin, S Kar, A Karasu Uysal, O Karavichev, T Karavicheva, L Karayan, E Karpechev, U Kebschull, R Keidel, D L D Keijdener, M Keil, B Ketzer, P Khan, S A Khan, A Khanzadeev, Y Kharlov, A Khatun, A Khuntia, M M Kielbowicz, B Kileng, D Kim, D W Kim, D J Kim, H Kim, J S Kim, J Kim, M Kim, M Kim, S Kim, T Kim, S Kirsch, I Kisel, S Kiselev, A Kisiel, G Kiss, J L Klay, C Klein, J Klein, C Klein-Bösing, S Klewin, A Kluge, M L Knichel, A G Knospe, C Kobdaj, M Kofarago, T Kollegger, A Kolojvari, V Kondratiev, N Kondratyeva, E Kondratyuk, A Konevskikh, M Kopcik, M Kour, C Kouzinopoulos, O Kovalenko, V Kovalenko, M Kowalski, G Koyithatta Meethaleveedu, I Králik, A Kravčáková, M Krivda, F Krizek, E Kryshen, M Krzewicki, A M Kubera, V Kučera, C Kuhn, P G Kuijer, A Kumar, J Kumar, L Kumar, S Kumar, S Kundu, P Kurashvili, A Kurepin, A B Kurepin, A Kuryakin, S Kushpil, M J Kweon, Y Kwon, S L La Pointe, P La Rocca, C Lagana Fernandes, I Lakomov, R Langoy, K Lapidus, C Lara, A Lardeux, A Lattuca, E Laudi, R Lavicka, L Lazaridis, R Lea, L Leardini, S Lee, F Lehas, S Lehner, J Lehrbach, R C Lemmon, V Lenti, E Leogrande, I León Monzón, P Lévai, S Li, X Li, J Lien, R Lietava, S Lindal, V Lindenstruth, C Lippmann, M A Lisa, V Litichevskyi, H M Ljunggren, W J Llope, D F Lodato, P I Loenne, V Loginov, C Loizides, P Loncar, X Lopez, E López Torres, A Lowe, P Luettig, M Lunardon, G Luparello, M Lupi, T H Lutz, A Maevskaya, M Mager, S Mahajan, S M Mahmood, A Maire, R D Majka, M Malaev, I Maldonado Cervantes, L Malinina, D Mal'Kevich, P Malzacher, A Mamonov, V Manko, F Manso, V Manzari, Y Mao, M Marchisone, J Mareš, G V Margagliotti, A Margotti, J Margutti, A Marín, C Markert, M Marquard, N A Martin, P Martinengo, J A L Martinez, M I Martínez, G Martínez García, M Martinez Pedreira, A Mas, S Masciocchi, M Masera, A Masoni, A Mastroserio, A M Mathis, A Matyja, C Mayer, J Mazer, M Mazzilli, M A Mazzoni, F Meddi, Y Melikyan, A Menchaca-Rocha, E Meninno, J Mercado Pérez, M Meres, S Mhlanga, Y Miake, M M Mieskolainen, D L Mihaylov, K Mikhaylov, L Milano, J Milosevic, A Mischke, A N Mishra, D Miśkowiec, J Mitra, C M Mitu, N Mohammadi, B Mohanty, M Mohisin Khan, E Montes, D A Moreira De Godoy, L A P Moreno, S Moretto, A Morreale, A Morsch, V Muccifora, E Mudnic, D Mühlheim, S Muhuri, M Mukherjee, J D Mulligan, M G Munhoz, K Münning, R H Munzer, H Murakami, S Murray, L Musa, J Musinsky, C J Myers, B Naik, R Nair, B K Nandi, R Nania, E Nappi, A Narayan, M U Naru, H Natal da Luz, C Nattrass, S R Navarro, K Nayak, R Nayak, T K Nayak, S Nazarenko, A Nedosekin, R A Negrao De Oliveira, L Nellen, S V Nesbo, F Ng, M Nicassio, M Niculescu, J Niedziela, B S Nielsen, S Nikolaev, S Nikulin, V Nikulin, F Noferini, P Nomokonov, G Nooren, J C C Noris, J Norman, A Nyanin, J Nystrand, H Oeschler, S Oh, A Ohlson, T Okubo, L Olah, J Oleniacz, A C Oliveira Da Silva, M H Oliver, J Onderwaater, C Oppedisano, R Orava, M Oravec, A Ortiz Velasquez, A Oskarsson, J Otwinowski, K Oyama, Y Pachmayer, V Pacik, D Pagano, P Pagano, G Paić, P Palni, J Pan, A K Pandey, S Panebianco, V Papikyan, G S Pappalardo, P Pareek, J Park, W J Park, S Parmar, A Passfeld, S P Pathak, V Paticchio, R N Patra, B Paul, H Pei, T Peitzmann, X Peng, L G Pereira, H Pereira Da Costa, D Peresunko, E Perez Lezama, V Peskov, Y Pestov, V Petráček, V Petrov, M Petrovici, C Petta, R P Pezzi, S Piano, M Pikna, P Pillot, L O D L Pimentel, O Pinazza, L Pinsky, D B Piyarathna, M Pł Oskoń, M Planinic, J Pluta, S Pochybova, P L M Podesta-Lerma, M G Poghosyan, B Polichtchouk, N Poljak, W Poonsawat, A Pop, H Poppenborg, S Porteboeuf-Houssais, J Porter, J Pospisil, V Pozdniakov, S K Prasad, R Preghenella, F Prino, C A Pruneau, I Pshenichnov, M Puccio, G Puddu, P Pujahari, V Punin, J Putschke, H Qvigstad, A Rachevski, S Raha, S Rajput, J Rak, A Rakotozafindrabe, L Ramello, F Rami, D B Rana, R Raniwala, S Raniwala, S S Räsänen, B T Rascanu, D Rathee, V Ratza, I Ravasenga, K F Read, K Redlich, A Rehman, P Reichelt, F Reidt, X Ren, R Renfordt, A R Reolon, A Reshetin, K Reygers, V Riabov, R A Ricci, T Richert, M Richter, P Riedler, W Riegler, F Riggi, C Ristea, M Rodríguez Cahuantzi, K Røed, E Rogochaya, D Rohr, D Röhrich, P S Rokita, F Ronchetti, L Ronflette, P Rosnet, A Rossi, A Rotondi, F Roukoutakis, A Roy, C Roy, P Roy, A J Rubio Montero, O V Rueda, R Rui, R Russo, A Rustamov, E Ryabinkin, Y Ryabov, A Rybicki, S Saarinen, S Sadhu, S Sadovsky, K Šafařík, S K Saha, B Sahlmuller, B Sahoo, P Sahoo, R Sahoo, S Sahoo, P K Sahu, J Saini, S Sakai, M A Saleh, J Salzwedel, S Sambyal, V Samsonov, A Sandoval, D Sarkar, N Sarkar, P Sarma, M H P Sas, E Scapparone, F Scarlassara, R P Scharenberg, H S Scheid, C Schiaua, R Schicker, C Schmidt, H R Schmidt, M O Schmidt, M Schmidt, S Schuchmann, J Schukraft, Y Schutz, K Schwarz, K Schweda, G Scioli, E Scomparin, R Scott, M Šefčík, J E Seger, Y Sekiguchi, D Sekihata, I Selyuzhenkov, K Senosi, S Senyukov, E Serradilla, P Sett, A Sevcenco, A Shabanov, A Shabetai, O Shadura, R Shahoyan, A Shangaraev, A Sharma, A Sharma, M Sharma, M Sharma, N Sharma, A I Sheikh, K Shigaki, Q Shou, K Shtejer, Y Sibiriak, S Siddhanta, K M Sielewicz, T Siemiarczuk, D Silvermyr, C Silvestre, G Simatovic, G Simonetti, R Singaraju, R Singh, V Singhal, T Sinha, B Sitar, M Sitta, T B Skaali, M Slupecki, N Smirnov, R J M Snellings, T W Snellman, J Song, M Song, F Soramel, S Sorensen, F Sozzi, E Spiriti, I Sputowska, B K Srivastava, J Stachel, I Stan, P Stankus, E Stenlund, J H Stiller, D Stocco, P Strmen, A A P Suaide, T Sugitate, C Suire, M Suleymanov, M Suljic, R Sultanov, M Šumbera, S Sumowidagdo, K Suzuki, S Swain, A Szabo, I Szarka, A Szczepankiewicz, M Szymanski, U Tabassam, J Takahashi, G J Tambave, N Tanaka, M Tarhini, M Tariq, M G Tarzila, A Tauro, G Tejeda Muñoz, A Telesca, K Terasaki, C Terrevoli, B Teyssier, D Thakur, S Thakur, D Thomas, R Tieulent, A Tikhonov, A R Timmins, A Toia, S Tripathy, S Trogolo, G Trombetta, V Trubnikov, W H Trzaska, B A Trzeciak, T Tsuji, A Tumkin, R Turrisi, T S Tveter, K Ullaland, E N Umaka, A Uras, G L Usai, A Utrobicic, M Vala, J Van Der Maarel, J W Van Hoorne, M van Leeuwen, T Vanat, P Vande Vyvre, D Varga, A Vargas, M Vargyas, R Varma, M Vasileiou, A Vasiliev, A Vauthier, O Vázquez Doce, V Vechernin, A M Veen, A Velure, E Vercellin, S Vergara Limón, R Vernet, R Vértesi, L Vickovic, S Vigolo, J Viinikainen, Z Vilakazi, O Villalobos Baillie, A Villatoro Tello, A Vinogradov, L Vinogradov, T Virgili, V Vislavicius, A Vodopyanov, M A Völkl, K Voloshin, S A Voloshin, G Volpe, B von Haller, I Vorobyev, D Voscek, D Vranic, J Vrláková, B Wagner, J Wagner, H Wang, M Wang, D Watanabe, Y Watanabe, M Weber, S G Weber, D F Weiser, J P Wessels, U Westerhoff, A M Whitehead, J Wiechula, J Wikne, G Wilk, J Wilkinson, G A Willems, M C S Williams, B Windelband, W E Witt, S Yalcin, P Yang, S Yano, Z Yin, H Yokoyama, I-K Yoo, J H Yoon, V Yurchenko, V Zaccolo, A Zaman, C Zampolli, H J C Zanoli, N Zardoshti, A Zarochentsev, P Závada, N Zaviyalov, H Zbroszczyk, M Zhalov, H Zhang, X Zhang, Y Zhang, C Zhang, Z Zhang, C Zhao, N Zhigareva, D Zhou, Y Zhou, Z Zhou, H Zhu, J Zhu, X Zhu, A Zichichi, A Zimmermann, M B Zimmermann, S Zimmermann, G Zinovjev, J Zmeskal
The invariant differential cross sections for inclusive [Formula: see text] and [Formula: see text] mesons at midrapidity were measured in pp collisions at [Formula: see text] TeV for transverse momenta [Formula: see text] GeV/c and [Formula: see text] GeV/c, respectively, using the ALICE detector. This large range in [Formula: see text] was achieved by combining various analysis techniques and different triggers involving the electromagnetic calorimeter (EMCal). In particular, a new single-cluster, shower-shape based method was developed for the identification of high-[Formula: see text] neutral pions, which exploits that the showers originating from their decay photons overlap in the EMCal...
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28892583/fluorescent-probe-dcvj-shows-high-sensitivity-for-characterization-of-amyloid-%C3%AE-peptide-early-in-the-lag-phase
#18
Sureshbabu Nagarajan, Lisa J Lapidus
The aggregation of intrinsically disordered and misfolded proteins in the form of oligomers and fibrils plays a crucial role in a number of neurological and neurodegenerative diseases. Currently, most probes and biophysical techniques that detect and characterize fibrils at high resolution fail to show sensitivity and binding for oligomers. Here, we show that 9-(dicyano-vinyl)julolidine (DCVJ), a class of molecular rotor, binds amyloid beta (Aβ) early aggregates, and we report the kinetics as well as packing of the oligomer formation...
September 11, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28835354/comparing-inpatient-satisfaction-collected-via-a-web-based-questionnaire-self-completion-and-through-a-telephone-interview-an-ancillary-study-of-the-sentipat-randomized-controlled-trial
#19
Sarah F Feldman, Nathanael Lapidus, Jacques Cosnes, Emmanuel Tiret, Laurent Fonquernie, Jean Cabane, Olivier Chazouilleres, Laure Surgers, Marc Beaussier, Alain-Jacques Valleron, Fabrice Carrat, Gilles Hejblum
BACKGROUND: Assessing the satisfaction of patients about the health care they have received is relatively common nowadays. In France, the satisfaction questionnaire, I-Satis, is deployed in each institution admitting inpatients. Internet self-completion and telephone interview are the two modes of administration for collecting inpatient satisfaction that have never been compared in a multicenter randomized experiment involving a substantial number of patients. OBJECTIVE: The objective of this study was to compare two modes of survey administration for collecting inpatient satisfaction: Internet self-completion and telephone interview...
August 23, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28801865/faecal-lactoferrin-and-calprotectin-in-patients-with-clostridium-difficile-infection-a-case-control-study
#20
F Barbut, C Gouot, N Lapidus, L Suzon, R Syed-Zaidi, V Lalande, C Eckert
Calprotectin and lactoferrin are released by the gastrointestinal tract in response to infection and mucosal inflammation. Our objective was to assess the usefulness of quantifying faecal lactoferrin and calprotectin concentrations in Clostridium difficile infection (CDI) patients with or without free toxins in the stools. We conducted a single-centre 22-month case-control study. Patients with a positive CDI diagnosis were compared to two control groups: group 1 = diarrhoeic patients negative for C. difficile and matched (1:1) to CDI cases on the ward location and age, and group 2 = diarrhoeic patients colonised with a non-toxigenic strain of C...
August 12, 2017: European Journal of Clinical Microbiology & Infectious Diseases
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