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https://www.readbyqxmd.com/read/29876264/age-related-diffusion-and-tractography-changes-in-typically-developing-pediatric-cervical-and-thoracic-spinal-cord
#1
Mahdi Alizadeh, Joshua Fisher, Sona Saksena, Yusra Sultan, Chris J Conklin, Devon M Middleton, Laura Krisa, Jürgen Finsterbusch, Adam E Flanders, Scott H Faro, M J Mulcahey, Feroze B Mohamed
Background and objective: Diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) are two techniques that can measure white matter integrity of the spinal cord. Recently, DTI indices have been shown to change with age. The purpose of this study is (a) to evaluate the maturational states of the entire pediatric spinal cord using DTI and DTT indices including fractional anisotropy (FA), mean diffusivity (MD), mean length of white matter fiber tracts and tract density and (b) to analyze the DTI and DTT parameters along the entire spinal cord as a function of spinal cord levels and age...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29858667/bone-mesenchymal-stem-cells-attenuate-radicular-pain-by-inhibiting-microglial-activation-in-a-rat-noncompressive-disk-herniation-model
#2
Xiaodong Huang, Weiheng Wang, Xilin Liu, Yanhai Xi, Jiangming Yu, Xiangqun Yang, Xiaojian Ye
Spinal disk herniation can induce radicular pain through chemical irritation caused by proinflammatory and immune responses. Bone marrow mesenchymal stem cells (BMSCs) are a unique type of adult stem cell with the functions of suppressing inflammation and modulating immune responses. This study was undertaken to observe the effect of intrathecal BMSCs on the treatment of mechanical allodynia and the suppression of microglial activation in a rat noncompressive disk herniation model. The model was induced by the application of nucleus pulposus (NP) to the L5 dorsal root ganglion (DRG)...
June 1, 2018: Cell and Tissue Research
https://www.readbyqxmd.com/read/29851799/short-term-effects-of-minimally-invasive-dynamic-neutralization-system-for-the-treatment-of-lumbar-spinal-stenosis-an-observational-study
#3
Ji Tu, Wenbin Hua, Wentian Li, Wei Liu, Rongjin Luo, Shuai Li, Yukun Zhang, Liang Kang, Kun Wang, Yu Song, Shuahua Yang, Cao Yang
The aim of the study was to evaluate the safety and short-term effects of dynamic stabilization via minimally invasive system for degenerative lumbar spinal stenosis. Patients with degenerative lumbar spinal stenosis and treated with Transforaminal Lumbar Interbody Fusion via minimally invasive minimally system (mis-TLIF) were served as the control group.From April 2011 to March 2015, 47 patients (29 male, 18 female; mean age 47.6 [range, 26-52] years) with lumbar spinal stenosis were treated with decompression and excision of herniated disk via the minimally invasive system combined with the dynamic fixation technique, and 42 patients as control group with mis-TLIF...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29808632/lumbar-canal-stenosis-can-we-treat-it-endoscopically-our-experience
#4
Leonello Tacconi, Roberto Spinelli
BACKGROUND: The common treatment for lumbar canal stenosis involves an open surgical decompression with laminectomy and foraminotomy, even if spinal surgery is moving towards minimal invasiveness procedures. Minimal Invasive Surgery initially and recently spinal endoscopic techniques are becoming the standard procedures for lumbar disk prolapsed in consideration of the less surgical invasiveness with a considerable reducing in the amount of normal anatomy violation, in less risk of iatrogenic post-operative instability, minimal scar tissue formation and negligible blood loss when compared to the standard open approach...
May 28, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29807187/radiographic-analysis-of-the-listhesis-associated-with-lumbar-isthmic-spondylolysis
#5
Jean Legaye
BACKGROUND: In cases of spondylolysis, hypoplasia of L5 mimicking spondylolisthesis has been described, mainly based on MRI; however, the treatment implications have not been analyzed specifically. OBJECTIVE: Assess the impact of hypoplasia of the L5 vertebral body in the constitution of the spondylolisthesis associated with isthmic spondylolysis. MATERIAL AND METHODS: A retrospective radiographic study in the standing position was performed with 104 patients with L5 isthmic spondylolysis and 24 control subjects...
May 25, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29798587/-short-term-effectiveness-of-accurate-decompression-via-foraminoplasty-in-treatment-of-lumbar-lateral-recess-stenosis
#6
Yu Wang, Qingquan Kong, Yueming Song
Objective: To discuss the effectiveness and the safety of accurate decompression via foraminoplasty in treating lumbar lateral recess stenosis patients who accompanied by disk-flavum ligamentum space and bony lateral recess stenosis, and to analysis the short-term effectiveness of the surgical procedures. Methods: Forty-five lumbar lateral recess stenosis patients accompanied by disk-flavum ligamentum space and bony lateral recess stenosis were treated by accurate decompression via foraminoplasty between January 2013 and January 2016...
November 1, 2017: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29721126/simultaneous-occurrence-of-spinal-epidural-abscess-and-disk-herniation-causing-irreversible-neurologic-deficits-a-case-report-and-review-of-the-literature
#7
Abdullah Cetinkaya, Claude Pierre-Jerome
No abstract text is available yet for this article.
June 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29713416/relationship-between-displacement-of-the-psoas-major-muscle-and-spinal-alignment-in-patients-with-adult-spinal-deformity
#8
Yoshiaki Oda, Tomoyuki Takigawa, Ryo Ugawa, Yasuyuki Shiozaki, Haruo Misawa, Yoshihisa Sugimoto, Masato Tanaka, Toshifumi Ozaki
Study Design: Cross sectional study. Purpose: To clarify the difference in position of the psoas muscle between adult spinal deformity (ASD) and lumbar spinal stenosis (LSS). Overview of Literature: Although it is known that the psoas major muscle deviates in ASD patients, no report is available regarding the difference in comparison with LSS patients. Methods: This study investigates 39 patients. For evaluating spinal alignment, pelvic tilt (PT), pelvic incidence (PI), sacral slope, lumbar lordosis (LL), PI-LL, Cobb angle, and the convex side, the lumbar curves were measured...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29656879/analysis-of-changes-in-cervical-spinal-curvature-and-intervertebral-disk-space-height-following-acdf-surgery-in-a-group-of-100-patients-followed-up-for-12-months
#9
Bartosz Godlewski, Magdalena Katarzyna Stachura, Ryszard Adam Czepko, Mariusz Banach, Ryszard Czepko
We analysed 100 patients following anterior cervical discectomy and fusion with interbody stabilisation with PEEK cages. Radiographs obtained preoperatively and during the 12-month follow-up were compared to track changes in overall and local cervical lordosis and disk space height. Subsidence was defined as cage migration ≥ 3 mm into the adjacent endplates. Mean change in operated disk space height was 1.13 ± 1.33 mm. Subsidence was detected in 10.23% of the operated spaces. Mean change in overall cervical lordosis was 1...
June 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29652779/is-the-current-management-of-patients-presenting-with-spinal-trauma-to-district-general-hospitals-fit-for-purpose-our-experience-of-delivering-a-spinal-service-using-an-electronic-referral-platform-in-a-large-district-general-teaching-hospital-without-onsite
#10
Daniel S Hill, Hans Marynissen
STUDY DESIGN: A retrospective cross-sectional analysis. OBJECTIVE: To describe the provision of a spinal service using an electronic platform to direct management from an external spinal unit, and quantify time taken to obtain definitive management plans whilst under prescribed spinal immobilization. SUMMARY OF BACKGROUND DATA: Most attending district general hospitals following spinal trauma will have stable injuries and normal neurology, with only a small proportion requiring urgent transfer to a specialist centre...
April 12, 2018: Spine
https://www.readbyqxmd.com/read/29595747/postoperative-infection-in-patients-undergoing-posterior-lumbosacral-spinal-surgery-a-pictorial-guide-for-diagnosis-and-early-treatment
#11
Shih-Hao Chen, Wen-Jer Chen, Meng-Huang Wu, Jen-Chung Liao, Chen-Ju Fu
Surgical site infections after posterior spinal surgery may lead to spondylodiscitis, pseudarthrosis, correction loss, adverse neurological sequelae, sepsis, and poor outcomes if not treated immediately. Infection rates vary depending on the type and extent of operative procedures, use of instrumentation, and patients' risk factors. Image evaluation is crucial for early diagnosis and should be complementary to clinical routes, laboratory survey, and treatment timing. Magnetic resonance imaging detects early inflammatory infiltration into the vertebrae and soft tissues, including hyperemic changes of edematous marrow, vertebral endplate, and abscess or phlegmon accumulation around the intervertebral disk, epidural, and paravertebral spaces...
March 27, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29593901/frequent-benign-nontraumatic-noninflammatory-causes-of-low-back-pain-in-adolescents-mri-findings
#12
Aikaterini Solomou, Pantelis Kraniotis, Aspasia Rigopoulou, Theodore Petsas
Introduction: Low back pain (LBP) is common in children and adolescents. There are many factors that cause LBP, including structural disorders, degenerative changes, Scheuermann's disease, fractures, inflammation, and tumors. Magnetic Resonance Imaging is the gold standard for diagnosing spinal abnormalities and is mandatory when neurological symptoms exist. The study focuses on common MRI findings in adolescents with persistent LBP, without history of acute trauma or evidence of either inflammatory or rheumatic disease...
2018: Radiology Research and Practice
https://www.readbyqxmd.com/read/29548949/predictive-factors-of-successful-percutaneous-cervical-nucleoplasty-for-the-treatment-of-pain-with-cervical-herniated-disk
#13
Min Kyoung Kim, Sung Eun Sim, Yong-Chul Kim, Jung Soo Kim, Seok Min Kwon, Yongjae Yoo, Chang-Soon Lee, Jee Youn Moon
BACKGROUND: Percutaneous cervical nucleoplasty (PCN) is an effective treatment for cervical herniated intervertebral disc (C-HIVD). In this retrospective study, we evaluated clinical predictors that affect the successful outcome of PCN. METHODS: Fluoroscopically guided PCN was conducted for C-HIVD by one pain physician. Successful outcome was defined as a combination of greater than 50% pain relief on the numerical rating scale pain score, no increase in analgesics, and no cervical epidural steroid injection during the 3-month follow-up period...
March 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29510816/adjuvant-analgesics-for-spine-surgery
#14
Rikke Vibeke Nielsen
Increasing evidence indicate that pain is insufficiently treated following surgical procedures. It is essential that pain treatment is effective with a minimum of side effects in order to promote postoperative rehabilitation. Multimodal analgesia is most likely an important strategy in reducing postoperative pain. Combinations of different analgesics with different mechanisms of action may have an additive analgesic effect with fewer side effects compared to using a single drug. However, there is still a pronounced lack of documentation for the effect and side effects of these multimodal analgesic regimes...
March 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29497616/magnetic-resonance-imaging-signal-alterations-in-paraspinal-muscles-in-dogs-with-acute-thoracolumbar-intervertebral-disk-extrusion
#15
Peter Trampus, Christine Goepfert, Monika Welle, Diana Henke, Franck Forterre, Daniela Schweizer-Gorgas
Muscle signal alteration detected on MRI is seen in diverse pathologic conditions. We observed signal alterations within the paraspinal muscles in dogs with acute thoracolumbar intervertebral disk extrusion. The aim of this retrospective study was to describe MRI features of paraspinal muscle signal alteration in dogs with acute thoracolumbar intervertebral disk extrusion and to investigate an association of the signal alterations with neurological grade, type and location of intervertebral disk extrusion, degree of spinal cord compression, and presence of epidural hemorrhage...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29393738/lumbar-hemilaminectomy-for-treatment-of-diskospondylitis-in-an-aardvark-orycteropus-afer
#16
Benjamin N Nevitt, Michael J Adkesson, Gwen Jankowski, Paula West, Jennifer N Langan
CASE DESCRIPTION A 17-year-old sexually intact male aardvark (Orycteropus afer) was evaluated because of hind limb proprioception deficits and ataxia. CLINICAL FINDINGS Results of examination and CT suggested a diagnosis of intervertebral disk disease and diskospondylitis at the L2-3 intervertebral space. Magnetic resonance imaging of the vertebral column also indicated intervertebral disk rupture with spinal cord compression and inflammation of the adjacent epaxial musculature TREATMENT AND OUTCOME Hemilaminectomy was performed according to the technique described for dogs...
February 15, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29386408/transcutaneous-spinal-direct-current-stimulation-of-the-lumbar-and-sacral-spinal-cord-a-modelling-study
#17
Sofia R Fernandes, Ricardo Salvador, Cornelia Wenger, M de Carvalho, Pedro C Miranda
OBJECTIVE: Our aim was to perform a computational study of the electric field (E-field) generated by transcutaneous spinal direct current stimulation (tsDCS) applied over the thoracic, lumbar and sacral spinal cord, in order to assess possible neuromodulatory effects on spinal cord circuitry related with lower limb functions. APPROACH: A realistic volume conductor model of the human body consisting of 14 tissues was obtained from available databases. Rubber pad electrodes with a metallic connector and a conductive gel layer were modelled...
February 9, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29340936/application-of-color-transformation-techniques-in-pediatric-spinal-cord-mr-images-typically-developing-and-spinal-cord-injury-population
#18
Mahdi Alizadeh, Pallav Shah, Chris J Conklin, Devon M Middleton, Sona Saksena, Adam E Flanders, Laura Krisa, M J Mulcahey, Scott H Faro, Feroze B Mohamed
The purpose of this study was to evaluate an improved and reliable visualization method for pediatric spinal cord MR images in healthy subjects and patients with spinal cord injury (SCI). A total of 15 pediatric volunteers (10 healthy subjects and 5 subjects with cervical SCI) with a mean age of 11.41 years (range 8-16 years) were recruited and scanned using a 3.0T Siemens Verio MR scanner. T2-weighted axial images were acquired covering entire cervical spinal cord level C1 to C7. These gray-scale images were then converted to color images by using five different techniques including hue-saturation-value (HSV), rainbow, red-green-blue (RGB), and two enhanced RGB techniques using automated contrast stretching and intensity inhomogeneity correction...
January 16, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29329586/il-33-st2-signaling-contributes-to-radicular-pain-by-modulating-mapk-and-nf-%C3%AE%C2%BAb-activation-and-inflammatory-mediator-expression-in-the-spinal-cord-in-rat-models-of-noncompressive-lumber-disk-herniation
#19
Si-Jian Huang, Jian-Qin Yan, Hui Luo, Lu-Yao Zhou, Jian-Gang Luo
BACKGROUND: Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammatory responses in a wide range of inflammatory and autoimmune disorders of the nervous system. Thus, the purpose of this study is to investigate the expression of IL-33 and its receptor ST2 in the dorsal spinal cord and to elucidate whether the inhibition of spinal IL-33 expression significantly attenuates pain-related behaviors in rat models of noncompressive lumbar disc herniation...
January 12, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29315121/cervical-total-disk-arthroplasty
#20
Timothy T Roberts, Ryan J Filler, Jason W Savage, Edward C Benzel
In the United States, cervical total disk arthroplasty (TDA) is US Federal Drug Administration (FDA) approved for use in both 1 and 2-level constructions for cervical disk disease resulting in myelopathy and/or radiculopathy. TDA designs vary in form, function, material composition, and even performance in?vivo. However, the therapeutic goals are the same: to remove the painful degenerative/damaged elements of the intervertebral discoligamenous joint complex, to preserve or restore the natural range of spinal motion, and to mitigate stresses on adjacent spinal segments, thereby theoretically limiting adjacent segment disease (ASDis)...
February 2018: Clinical Spine Surgery
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