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Low income cancer

Stevan Bruijns, Camillo Lamanna
Healthcare-related research is largely regional. Put simply, this is because disease burdens differ between world regions. Even global burdens, such as ischaemic heart disease and cancer, display distinctive characteristics in certain regions that are not seen in others. Regional differences in infrastructure, resources and human capital further compound the differences seen, as they affect the way in which the local scientific community can interact with the local disease burden. As such, it seems fair to assume that healthcare-related research ought to be regionally distributed...
2018: Ecancermedicalscience
Louise Soanes, Faith Gibson
BACKGROUND: For adolescents and young adults living in high-income countries cancer remains the most common disease-related death. Increasing survival rates and projected longevity are positive outcomes, although long-term consequences of cancer and/or its treatment will likely increase the global burden of cancer. In low and middle-income countries the impact and needs of young adults with cancer are largely unknown and require further attention. However, universal studies have revealed that cancer-related needs for this group are multifactorial, complex and largely unmet...
January 31, 2018: International Journal of Nursing Studies
Kathleen Melan, Frederic Amant, Jacqueline Veronique-Baudin, Clarisse Joachim, Eustase Janky
BACKGROUND: Fertility preservation (FP) is a major determinant of quality of life after cancer remission for women who may not have achieved their ideal family size. This article describes the FP services and strategy currently available, highlighting issues of oncofertility worldwide. For these patients in complex situations, health networks are essential to improve coordination of care, and the strengthening of this coordination is a major challenge to improve the performance of the health system...
February 17, 2018: BMC Cancer
Mersiha Mahmić-Kaknjo, Antonia Jeličić-Kadić, Ana Utrobičić, Kit Chan, Lisa Bero, Ana Marušić
OBJECTIVE: To identify uses of WHO Model list of essential medicines (EM) and summarize studies examining essential medicines (EM) and national EM lists (NEMLs). STUDY DESIGN AND SETTING: In this scoping review, we searched PubMed, Scopus, WHO website and WHO Regional Databases for studies on NEMLs, reimbursement medicines lists, and WHO EML, with no date or language restrictions. RESULTS: 3,144 retrieved documents were independently screened by two reviewers; 100 full-text documents were analyzed; 37 contained data suitable for quantitative and qualitative analysis on EMs availability (11 documents), medicines for specific diseases (13 documents), and comparison of WHO EML and NEMLs (13 documents)...
February 13, 2018: Journal of Clinical Epidemiology
Victor Aboyans, Marie-Antoinette Sevestre, Ileana Désormais, Philippe Lacroix, Gerry Fowkes, Michael H Criqui
It is estimated that more than 200 million individuals are affected by lower extremity artery disease (LEAD) worldwide. This prevalence has increased between 2000 and 2010 by 25%, especially in low/middle income countries. In France, about one million people are affected by this condition. Almost two-thirds of patients with LEAD are asymptomatic. This explains the interest of the measurement of the ankle-brachial index (ABI), an objective and harmless diagnostic tool. An ABI≤0.90 is considered as diagnostic for LEAD...
February 12, 2018: La Presse Médicale
Sarah C Markt, Tianyu Tang, Angel M Cronin, Ingrid T Katz, Brooke E Howitt, Neil S Horowitz, Larissa J Lee, Alexi A Wright
Cervical cancer outcomes remain poor among disadvantaged populations, including ethnic minorities, low-income, and underinsured women. The aim of this study was to evaluate the mechanisms that underlie the observed association between race/ethnicity and cervical cancer survival. We identified 13,698 women, ages 21 to 64 years, diagnosed with stages I-III primary cervical cancer between 2007-2013 in Surveillance, Epidemiology, and End Results (SEER). Multivariable Cox proportional hazards regression models evaluated associations between race/ethnicity (Non-Hispanic White, Non-Hispanic Black, Hispanic, Other) and cervical cancer-specific mortality...
2018: PloS One
Mark Jit, Marc Brisson
Up to 2016, low- and middle-income countries mostly introduced routine human papillomavirus (HPV) vaccination for just a single age-cohort of girls each year. However, high income countries have reported large reductions in HPV prevalence following "catch-up" vaccination of multiple age-cohorts in the year of HPV vaccine introduction. We used the mathematical model PRIME to project the incremental impact of vaccinating 10-14-year old girls compared to routine HPV vaccination only in the same year that routine vaccination is expected to be introduced for 9-year old girls across 73 low and lower-middle income countries...
February 15, 2018: International Journal of Cancer. Journal International du Cancer
Enrique Soto-Perez-de-Celis, Viridana Perez-Montessoro, Patricia Rojo-Castillo, Yanin Chavarri-Guerra
Understanding the preferred sources of health-related information among patients with cancer is essential for designing successful cancer education and prevention strategies. However, little is known about health-related information-seeking practices among patients living in low- and middle-income countries. We studied the preferred sources of health-related information among Mexican patients with cancer and explored which factors influence these choices. The health-related information-seeking practices among patients with cancer treated at a public hospital in Mexico City were evaluated using questions from the Spanish Version of the Health Information National Trends Survey...
February 13, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
Monica M Rivera-Franco, Eucario Leon-Rodriguez
Breast cancer is the most common cancer in women in both developed and developing countries and the second most common cancer in the world. Developing countries are increasingly adopting a Western lifestyle, such as changes in diet and delayed first childbirth, lower parity, and shorter periods of breastfeeding, which are important determinants of a higher incidence of breast cancer among those regions. Low- and middle-income countries (LMICs) represent most of the countries with the highest mortality rates, ranging from 40% to 60%...
2018: Breast Cancer: Basic and Clinical Research
Halley Vora, Alice Chung, Azaria Lewis, Jim Mirocha, Farin Amersi, Armando Giuliano, Rodrigo F Alban
BACKGROUND: Surgical deserts (SDs) are defined as the geographic maldistribution of general surgeons of six or less per 100,000 population in underserved/rural counties. Disparities have been reported in breast cancer outcomes; however, the effect of SDs remains unknown. We sought to examine the effect of SDs on breast reconstruction (BR) after mastectomy and the differences between patients in both the cohorts. METHODS: Using the Nationwide Inpatient Sample database years 2007-2011, we identified International Classification of Diseases 9th edition codes for breast cancer, mastectomy, and BR in California...
March 2018: Journal of Surgical Research
Liliana Vasquez, Rosdali Diaz, Sharon Chavez, Fanny Tarrillo, Ivan Maza, Eddy Hernandez, Monica Oscanoa, Juan García, Jenny Geronimo, Nuria Rossell
BACKGROUND: Abandonment of treatment is a major cause of treatment failure and poor survival in children with cancer in low- and middle-income countries. The incidence of treatment abandonment in Peru has not been reported. The aim of this study was to examine the prevalence of and factors associated with treatment abandonment by pediatric patients with solid tumors in Peru. METHODS: We retrospectively reviewed the sociodemographic and clinical data of children referred between January 2012 and December 2014 to the two main tertiary centers for childhood cancer in Peru...
February 12, 2018: Pediatric Blood & Cancer
Jamal A Nabhani, Ruby Kuang, Hui Liu, Lorna Kwan, Mark S Litwin
PURPOSE: To evaluate the effect of transitioning from a prostate cancer-specific treatment program to comprehensive insurance under the Affordable Care Act (ACA) on the physical, mental, and prostate cancer-related health of poor, previously uninsured men. MATERIALS AND METHODS: We assessed general and prostate cancer-specific health-related quality of life (QOL) using the RAND 12-item short form health survey and UCLA Prostate Cancer Index at 3 time points in 24 men transitioning to comprehensive insurance (insured group) relative to 39 men remaining in the prostate cancer program (control group)...
February 6, 2018: Journal of Urology
Farida Selmouni, Ahmed Zidouh, Latifa Belakhel, Catherine Sauvaget, Maria Bennani, Youssef Chami Khazraji, Abdellatif Benider, Christopher P Wild, Rachid Bekkali, Ibtihal Fadhil, Rengaswamy Sankaranarayanan
Examples of successful implementations of national cancer control plans in low-income or middle-income countries remain rare. Morocco, a country where cancer is already the second leading cause of death after cardiovascular diseases, is one exception in this regard. Population ageing and lifestyle changes are the major drivers that are further increasing the cancer burden in the country. Facing this challenge, the Moroccan Ministry of Health has developed a we l planned and pragmatic National Plan for Cancer Prevention and Control (NPCPC) that, since 2010, has been implemented with government financial support to provide basic cancer care services across the entire range of cancer control...
February 2018: Lancet Oncology
Ariana Znaor, Sultan Eser, Hoda Anton-Culver, Ibtihal Fadhil, Anton Ryzhov, Barbara G Silverman, Karima Bendahou, Anna Demetriou, Omar Nimri, Cankut Yakut, Freddie Bray
The Global Initiative for Cancer Registry Development partnership, led by the International Agency for Research on Cancer (IARC), was established in response to an overwhelming need for high-quality cancer incidence data from low-income and middle-income countries. The IARC Regional Hub for cancer registration in North Africa, Central and West Asia was founded in 2013 to support capacity building for cancer registration in each of the countries in this region. In this Series paper, we advocate the necessity for tailored approaches to cancer registration given the rapidly changing cancer landscape for this region, and the challenges faced at a national level in developing data systems to help support this process given present disparities in resources and health infrastructure...
February 2018: Lancet Oncology
Sudha Sivaram, Gautam Majumdar, Douglas Perin, Ashrafun Nessa, Mireille Broeders, Elsebeth Lynge, Mona Saraiya, Nereo Segnan, Rengaswamy Sankaranarayanan, Preetha Rajaraman, Edward Trimble, Stephen Taplin, G K Rath, Ravi Mehrotra
The reductions in cancer morbidity and mortality afforded by population-based cancer screening programmes have led many low-income and middle-income countries to consider the implementation of national screening programmes in the public sector. Screening at the population level, when planned and organised, can greatly benefit the population, whilst disorganised screening can increase costs and reduce benefits. The International Cancer Screening Network (ICSN) was created to share lessons, experience, and evidence regarding cancer screening in countries with organised screening programmes...
February 2018: Lancet Oncology
John S Flanigan, Shannon L Silkensen, Nicholas G Wolf
Like in all areas of science, it is important for funders and investigators of pathology to work together to develop a well-designed, well-executed clinical research agenda. In the first section of this article, the authors discuss how the National Institutes of Health (NIH) peer-review process applies to global health pathology research projects. Then, the authors present an illustrative sampling of NIH-funded projects with performance sites in low- and middle-income countries with 2 examples focused on cancer and anatomic pathology...
March 2018: Clinics in Laboratory Medicine
Andrew S Field
Fine-needle aspiration cytology is a rapid, accurate, minimally invasive, inexpensive biopsy technique requiring minimal laboratory infrastructure and proceduralist costs. It provides infectious and noncommunicable disease diagnoses and will play an essential role in the establishment of cancer services in low-income and middle-income countries (LMICs). The use of molecular and other ancillary tests on cytology material is rapidly expanding in high-income countries and will spread to LMICs. Establishing cytology services requires increased training of cytopathologists and cytotechnologists, increased education of clinicians in the use of diagnostic cytopathology, and commitment and funding from governments and specialist training groups...
March 2018: Clinics in Laboratory Medicine
Yehoda M Martei, Lydia E Pace, Jane E Brock, Lawrence N Shulman
Breast cancer is the leading cause of cancer mortality among women in developing countries. Timely and accurate histopathological diagnosis of breast cancer is critical to delivering high-quality breast cancer care to patients in low- and middle-income countries (LMIC). The most important prognostic factors in breast cancer along with tumor size and nodal status are tumor grade, estrogen receptor status, as well as HER2 status in countries where specific targeted therapies are available. In addition, detailed and complete cancer registry data are needed to assess a country's disease burden and guide disease prioritization and allocation of resources for breast cancer treatment...
March 2018: Clinics in Laboratory Medicine
An Jen Chiang, Chung Chang, Chi Hsiang Huang, Wei Chun Huang, Yuen Yee Kan, Jiabin Chen
OBJECTIVE: The objective was to identify risk factors that were associated with the progression from endometriosis to ovarian cancer based on medical insurance data. METHODS: The study was performed on a dataset obtained from the National Health Insurance Research Database, which covered all the inpatient claim data from 2000 to 2013 in Taiwan. The International Classification of Diseases (ICD) code 617 was used to screen the dataset for the patients who were admitted to hospital due to endometriosis...
February 1, 2018: Journal of Gynecologic Oncology
Apichat Tantraworasin, Emanuela Taioli, Bian Liu, Andrew J Kaufman, Raja M Flores
BACKGROUND: Mediastinal lymph node evaluation (MLNE) is considered to be the standard of care in curative lung cancer surgery although it is not always performed. This study identifies factors associated with patients not being evaluated (non-MLNE) in cases of resectable non-small cell lung cancer. METHODS: A retrospective observational study using the Surveillance, Epidemiology, and End Results Program database was conducted. Adult patients diagnosed with non-small cell lung cancer stage I to IIIA (2004 to 2013) were included...
January 31, 2018: Annals of Thoracic Surgery
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