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https://www.readbyqxmd.com/read/28231283/rapid-evolution-of-distinct-helicobacter-pylori-subpopulations-in-the-americas
#1
Kaisa Thorell, Koji Yahara, Elvire Berthenet, Daniel J Lawson, Jane Mikhail, Ikuko Kato, Alfonso Mendez, Cosmeri Rizzato, María Mercedes Bravo, Rumiko Suzuki, Yoshio Yamaoka, Javier Torres, Samuel K Sheppard, Daniel Falush
For the last 500 years, the Americas have been a melting pot both for genetically diverse humans and for the pathogenic and commensal organisms associated with them. One such organism is the stomach-dwelling bacterium Helicobacter pylori, which is highly prevalent in Latin America where it is a major current public health challenge because of its strong association with gastric cancer. By analyzing the genome sequence of H. pylori isolated in North, Central and South America, we found evidence for admixture between H...
February 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28230243/global-disparities-in-cancer-pain-management-and-palliative-care
#2
Madhuri Are, Amanda McIntyre, Suresh Reddy
Palliative care and pain management constitute an integral part of the multi-disciplinary approach to treating patients with cancer. There are major disparities in the global presence of sustainable palliative care models and universal availability of effective pain medications, especially in low and middle income countries with the highest predicted future burden of cancer. Active intervention is needed to improve the availability of palliative care and effective pain control worldwide.
February 23, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28229562/out-of-pocket-costs-and-burden-among-rural-breast-cancer-survivors
#3
Maria Pisu, Andres Azuero, Rachel Benz, Patrick McNees, Karen Meneses
Little is known about out-of-pocket (OOP) costs incurred for medical and health needs by rural breast cancer survivors and what factors may be associated with higher OOP costs and the associated economic burden. Data were examined for 432 survivors participating in the Rural Breast Cancer Survivor Intervention trial. OOP costs were collected using the Work and Finances Inventory survey at baseline and four assessments every 3 months. Mean and median OOP costs and burden (percent of monthly income spent on OOP costs) were reported and factors associated with OOP costs and burden identified with generalized linear models fitted with over-dispersed gamma distributions and logarithmic links (OOP costs) and with beta distributions with logit link (OOP burden)...
February 23, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28228841/an-update-on-the-management-of-breast-cancer-in-africa
#4
REVIEW
V Vanderpuye, S Grover, N Hammad, PoojaPrabhakar, H Simonds, F Olopade, D C Stefan
BACKGROUND: There is limited information about the challenges of cancer management and attempts at improving outcomes in Africa. Even though South and North Africa are better resourceds to tackle the burden of breast cancer, similar poor prognostic factors are common to all countries. The five-year overall Survival rate for breast cancer patients does not exceed 60% for any low and middle-income country (LMIC) in Africa. In spite of the gains achieved over the past decade, certain characteristics remain the same such as limited availability of breast conservation therapies, inadequate access to drugs, few oncology specialists and adherence to harmful socio-cultural practices...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28225871/factors-related-to-non-adherence-to-mammography-in-a-city-of-the-brazilian-amazonian-area-a-population-based-study
#5
Camila Iasmim de Andrade Souza, Daniela Souza Araújo, Daniele Aparecida de Freitas Teles, Stéphanie Gomes Lins de Carvalho, Kyldery Wendell Moura Cavalcante, Wendell Lima Rabelo, Cibelli Navarro Rodrigues Alves, Allex Jardim da Fonseca
OBJECTIVE: To assess the prevalence of mammography use and factors related to non-adherence in Boa Vista, capital of Roraima, Brazil. METHOD: A cross sectional study, quantitative analysis, based on household survey was performed between June and August 2013, using a face-to-face interview with a pre-tested form. Target population was women between 40 and 69 years. The sample size target was 240 participants, and the sampling method was random cluster sampling. The study was approved by the Institutional Review Board of Federal University of Roraima...
January 1, 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28223433/global-cancer-in-women-burden-and-trends
#6
Lindsey A Torre, Farhad Islami, Rebecca L Siegel, Elizabeth M Ward, Ahmedin Jemal
There are striking disparities in the global cancer burden in women, yet few publications highlight cancer occurrence in this population, particularly for cancers that are not sex-specific. This paper, the first in a series of two, summarizes the current burden, trends, risk factors, prevention, early detection, and survivorship of all cancers combined and seven sites (breast, cervix, uterine corpus, ovary, colorectum, lung, and liver) that account for about 60% of the cancer burden among women worldwide, using data from the International Agency for Research on Cancer...
February 21, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28222082/challenges-encountered-by-vietnamese-nurses-when-caring-for-patients-with-cancer
#7
Ly Thuy Nguyen, Lourdes Clemenceau Annoussamy, Virginia T LeBaron
Providing holistic care is acknowledged as central to providing quality care for patients with cancer, but providing competent nursing care consistent with these approaches remains a challenge for nurses in Vietnam. Obstacles for Vietnamese oncology nurses include their low status, the limited scope of nursing practice, work overload in a hierarchical system, and cultural beliefs that view death and dying as taboo. Additional research to support oncology nurses in Vietnam must acknowledge the merits of improving nursing education as an important strategy for enhancing nursing autonomy, quality of care, and outcomes for the increasing number of patients with cancer in low- and middle-income countries...
March 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28221895/use-of-evidence-based-prostate-cancer-imaging-in-a-nongovernmental-integrated-health-care-system
#8
Ramzi G Salloum, Maureen O'Keeffe-Rosetti, Debra P Ritzwoller, Mark C Hornbrook, Jennifer Elston Lafata, Matthew E Nielsen
PURPOSE: The overuse of imaging, particularly for staging of low-risk prostate cancer, is well documented and widespread. The existing literature, which focuses on the elderly in fee-for-service settings, points to financial incentives as a driver of overuse and may not identify factors relevant to policy solutions within integrated health care systems, where physicians are salaried. METHODS: Imaging rates were analyzed among men with incident prostate cancer diagnosed between 2004 and 2011 within the Colorado and Northwest regions of Kaiser Permanente...
February 21, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28218584/occupational-engagement-in-low-income-latina-breast-cancer-survivors
#9
Alix G Sleight
OBJECTIVE: This qualitative study examined the experience of occupational engagement in low-income Latina breast cancer survivors and suggests the potential for occupational therapy practitioners to improve health outcomes in this vulnerable and underserved population. METHOD: Semistructured interviews were conducted with 9 participants. Inductive analysis was used to code for themes and patterns related to occupational engagement and quality of life (QOL). RESULTS: Lack of occupational engagement negatively affected QOL, but participation in occupations such as religious activity and caregiving promoted well-being...
March 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/28217724/quality-of-life-among-female-cancer-survivors-in-africa-an-integrative-literature-review
#10
REVIEW
Rhoda Suubi Muliira, Anna Santos Salas, Beverley O'Brien
Quality of life (QOL) has been studied extensively among cancer populations in high income countries where cancer care resources are available to many. Little is known concerning the QOL of cancer groups residing in Africa where resources can be scarce. The integrative review of the literature explored and critically examined studies that had addressed QOL in female cancer survivors in Africa. The extent to which QOL studies incorporated a cultural perspective was also examined. Research studies published between 2005 and 2015 were retrieved from five databases: CINAHL, MEDLINE, SCOPUS, ProQuest dissertations and Theses full text, and GlobalHealth...
January 2017: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28214281/patient-characterization-and-usage-trends-of-proton-beam-therapy-for-localized-prostate-cancer-in-the-united-states-a-study-of-the-national-cancer-database
#11
Arya Amini, David Raben, E David Crawford, Thomas W Flaig, Elizabeth R Kessler, Elaine T Lam, Paul Maroni, Thomas J Pugh
PURPOSE: To evaluate usage trends and identify factors associated with proton beam therapy (PBT) compared to alternative forms of external beam radiation therapy (RT) (EBRT) for localized prostate cancer. PATIENTS AND METHODS: The National Cancer Database was queried for men with localized (N0, M0) prostate cancer diagnosed between 2004 and 2013, treated with EBRT, with available data on EBRT modality (photon vs. PBT). Binary multiple logistic regression identified variables associated with EBRT modality...
February 14, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28210884/energy-balance-and-obesity-what-are-the-main-drivers
#12
Isabelle Romieu, Laure Dossus, Simón Barquera, Hervé M Blottière, Paul W Franks, Marc Gunter, Nahla Hwalla, Stephen D Hursting, Michael Leitzmann, Barrie Margetts, Chizuru Nishida, Nancy Potischman, Jacob Seidell, Magdalena Stepien, Youfa Wang, Klaas Westerterp, Pattanee Winichagoon, Martin Wiseman, Walter C Willett
PURPOSE: The aim of this paper is to review the evidence of the association between energy balance and obesity. METHODS: In December 2015, the International Agency for Research on Cancer (IARC), Lyon, France convened a Working Group of international experts to review the evidence regarding energy balance and obesity, with a focus on Low and Middle Income Countries (LMIC). RESULTS: The global epidemic of obesity and the double burden, in LMICs, of malnutrition (coexistence of undernutrition and overnutrition) are both related to poor quality diet and unbalanced energy intake...
February 17, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28203627/variations-in-gynecologic-oncology-training-in-low-lic-and-middle-income-mic-countries-lmics-common-efforts-and-challenges
#13
REVIEW
Carolyn Johnston, Joseph S Ng, Ranjit Manchanda, Audrey Tieko Tsunoda, Linus Chuang
Gynecologic cancer, cervical cancer in particular, is disproportionately represented in the developing world where mortality is also high. Screening programs, increased availability of chemotherapy, and an awareness of HIV-related cancers have in part accelerated a need for physicians who can treat these cancers, yet the infrastructure for such training is often lacking. In this paper, we address the variations in gynecology oncology training in LMICs as well as the ubiquitous challenges, in an effort to guide future agendas...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28203108/a-review-of-screening-strategies-for-cervical-cancer-in-human-immunodeficiency-virus-positive-women-in-sub-saharan-africa
#14
REVIEW
Manuela Viviano, Pierre DeBeaudrap, Pierre-Marie Tebeu, Jovanny T Fouogue, Pierre Vassilakos, Patrick Petignat
Cervical cancer (CC) is a leading cause of cancer-related death and a major public health issue in sub-Saharan Africa. This heavy burden parallels that of the human immunodeficiency virus (HIV) infection, which increases the risk of developing CC. Despite the progressive reduction of HIV prevalence in the past decade, the CC incidence and mortality rates in sub-Saharan Africa remain high. The heterogeneity of the distribution of the two diseases in the African continent, together with the different availability of human and material resources, stands in the way of finding an appropriate screening strategy...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28188941/association-between-breast-reconstruction-surgery-and-quality-of-life-in-iranian-breast-cancer-patients
#15
Farnaz Sinaei, Kazem Zendehdel, Mahsa Adili, Atefeh Ardestani, Ali Montazeri, Mohammad Ali Mohagheghi
Breast reconstruction (BR) surgery is not common for the treatment of breast cancer in low- and middle-income countries, including Iran. We evaluated the quality of life (QoL) in Iranian breast cancer patients who underwent BR at the Cancer Institute of Iran. We compared patients who had BR with breast cancer patients who had a radical mastectomy as the control group, matched for age, and time since surgery. We interviewed the cases and controls and collected data about QoL using EORTC-Q30 and EORTC-Q23 questionnaires...
January 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28188016/concurrent-chemoradiotherapy-vs-radiotherapy-alone-in-locally-advanced-cervix-cancer-a-systematic-review-and-meta-analysis
#16
REVIEW
Niloy Ranjan Datta, Emanuel Stutz, Michael Liu, Susanne Rogers, Dirk Klingbiel, Alexander Siebenhüner, Shalini Singh, Stephan Bodis
The efficacy of concurrent chemoradiotherapy (CTRT) in locally advanced cervix cancer (LACC, stages IIB-IVA) is contentious. This is due to the variable extent of therapeutic benefit reported in different randomized clinical trials and meta-analyses that usually include all stages of cervix cancer. A systematic review and meta-analysis was therefore conducted to evaluate the efficacy of concurrent CTRT over radiotherapy (RT) alone, predominantly in LACC for the key endpoints; complete response (CR), long-term loco-regional control (LRC), overall survival (OS), grade III/IV acute and late toxicities...
February 7, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28186936/narrowing-mortality-gap-between-men-and-women-over-two-decades-a-registry-based-study-in-ontario-canada
#17
Laura C Rosella, Andrew Calzavara, John W Frank, Tiffany Fitzpatrick, Peter D Donnelly, David Henry
BACKGROUND: Historically, women have lower all-cause mortality than men. It is less understood that sex differences have been converging, particularly among certain subgroups and causes. This has implications for public health and health system planning. Our objective was to analyse contemporary sex differences over a 20-year period. METHODS: We analysed data from a population-based death registry, the Ontario Registrar's General Death file, which includes all deaths recorded in Canada's most populous province, from 1992 to 2012 (N=1 710 080 deaths)...
November 14, 2016: BMJ Open
https://www.readbyqxmd.com/read/28183824/global-cancer-in-women-cancer-control-priorities
#18
Farhad Islami, Lindsey A Torre, Jeffrey M Drope, Elizabeth M Ward, Ahmedin Jemal
The global burden of cancer in women has recently received much attention, but there are few comprehensive reviews of the burden and policy approaches to reduce it. This paper, second in series of two, summarizes the most important cancer control priorities with specific examples of proven interventions, with a particular focus on primary prevention in low- and middle-income countries (LMICs). There are a number of effective cancer control measures available to countries of all resource levels. Many of these measures are extremely cost-effective, especially in the case of tobacco control and vaccination...
February 9, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28182258/improving-access-to-high-cost-cancer-drugs-in-latin-america-much-to-be-done
#19
REVIEW
Rossana Ruiz, Kathrin Strasser-Weippl, Diego Touya, Carmen Herrero Vincent, Abraham Hernandez-Blanquisett, Jessica St Louis, Alexandra Bukowski, Paul E Goss
Lack of access to high-cost medications is a complex issue at the intersection of economics, medicine, politics, and ethics, and it poses a significant threat to global health care. The problem is even more significant in low- and middle-income countries, such as those in Latin America, where governments and individuals struggle to pay for products that are priced at several times the level of their per capita gross domestic product. In this review, we examine the determinants for increasing drug costs and how Latin American countries face this burgeoning crisis...
February 9, 2017: Cancer
https://www.readbyqxmd.com/read/28179415/factors-related-to-receipt-of-non-cancer-related-transurethral-prostatectomy-findings-from-a-large-prospective-study-of-106%C3%A2-769-middle-aged-and-older-australian-men
#20
Grace Joshy, Kay Soga, Rosemary J Korda, Manish I Patel, Emily Banks
BACKGROUND: Transurethral prostatectomy (TURP) is a common surgical intervention for chronic lower urinary tract symptoms (LUTS). Little large-scale evidence exists on factors related to receipt of non-cancer-related TURP. METHODS: A prospective study of men aged ≥45 years participating in the 45 and Up Study, a large Australian cohort study, without prior prostatectomy and/or bowel/genital/urinary-tract cancer; questionnaire data were linked to hospitalisations and deaths...
February 8, 2017: BMJ Open
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