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https://www.readbyqxmd.com/read/28821832/development-of-enhanced-ethanol-ablation-as-an-alternative-to-surgery-in-treatment-of-superficial-solid-tumors
#1
Robert Morhard, Corrine Nief, Carlos Barrero Castedo, Fangyao Hu, Megan Madonna, Jenna L Mueller, Mark W Dewhirst, David F Katz, Nirmala Ramanujam
While surgery is at the foundation of cancer treatment, its access is limited in low-income countries. Here, we describe development of a low-cost alternative therapy based on intratumoral ethanol injection suitable for resource-limited settings. Although ethanol-based tumor ablation is successful in treating hepatocellular carcinomas, the necessity for multiple treatments, injection of large fluid volumes, and decreased efficacy in treatment of non-capsulated tumors limit its applicability. To address these limitations, we investigated an enhanced ethanol ablation strategy to retain ethanol within the tumor through the addition of ethyl cellulose...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28812191/improved-outcome-of-childhood-acute-myeloid-leukemia-in-an-eastern-european-country-lithuanian-experience
#2
Igne Kairiene, Ramune Pasauliene, Nadezda Lipunova, Goda Vaitkeviciene, Lina Rageliene, Jelena Rascon
The reported treatment outcomes of children treated for cancer in Eastern European countries are inferior to those in Northern/Western Europe. We hypothesized that recent survival rates could be comparable to the current standards and performed a population-based analysis of treatment outcome of childhood acute myeloid leukemia (AML) in Lithuania, a small Eastern European country. Children < 18 years old who were treated for AML from 2000 to 2013 were included (n = 54). Estimates of 5-year event-free (EFS5y) and overall survival (OS5y) rates were analyzed...
August 15, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28803088/treat-the-pain-program
#3
Megan O'Brien, Amanda Schwartz, Laura Plattner
CONTEXT: Globally, low and middle-income countries are home to 70% of cancer deaths and 99% of HIV deaths, but they consume just 7% of opioid analgesics. OBJECTIVE: The American Cancer Society's Treat the Pain program partners with governments in low and middle-income countries to improve access to high-quality essential pain medicines. METHOD: Treat the Pain has developed the MORPHINE Framework to provide a structure to describe challenges to access to pain relief and to group and sequence interventions to address these challenges...
August 9, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28801432/psychiatric-disorders-among-people-with-cancer-in-low-and-lower-middle-income-countries-study-protocol-for-a-systematic-review-and-meta-analysis
#4
Zoe J Walker, Michael P Jones, Arun V Ravindran
INTRODUCTION: Cancer is a rapidly growing public health problem in low- and lower-middle-income countries (LLMICs). There is evidence from upper-income countries that comorbid mental illness is common and can adversely impact cancer outcomes. Little is known about this burden in LLMICs. This systematic review has two aims. The first is to review the prevalence and patterns of psychiatric comorbidity in adults with cancer in LLMICs. The second is to review psychiatric treatment outcomes in this population...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801154/progress-in-prophylactic-human-papillomavirus-hpv-vaccination-in-2016-a-literature-review
#5
Polona J Maver, Mario Poljak
Prophylactic human papillomavirus (HPV) vaccine represents a revolutionary step forward in preventing HPV-related cancers, especially cervical carcinoma. Alongside appropriate screening, it has the potential to dramatically reduce cervical cancer incidence and even eradicate it. Following extensive evaluations in clinical trials, the first decade of routine HPV vaccine use provides overwhelming evidence of the vaccines' safety and their real-life effectiveness. In 2016, further clinical trials showed high vaccine efficacy in adult women, especially those that were HPV DNA-negative at baseline, and indicated possible protection from HPV-related diseases after treatment of precancerous cervical lesions...
August 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28799072/cervical-cancer-literacy-in-women-of-reproductive-age-and-its-related-factors
#6
Maryam Bazaz, Parvin Shahry, Sayed Mahmood Latifi, Marzieh Araban
Cancer health literacy, which is the ability to search, understand, and use health information to make appropriate health decisions, plays an important role in the use of preventative and screening information. The present study aims to evaluate cervical cancer health literacy in women of reproductive age and its related factors. In this cross-sectional study, 231 women of reproductive age who referred to health centers of Khuzestan Province, Iran, were selected via convenience sampling. A valid and reliable measure was employed to collect information about various dimensions of cervical cancer health literacy, including having access to, reading, understanding, appraising, using, and communicating it...
August 10, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28797046/breast-conservation-surgery-versus-total-mastectomy-among-women-with-localized-breast-cancer-in-soweto-south-africa
#7
Herbert Cubasch, Maureen Joffe, Paul Ruff, Donald Dietz, Evan Rosenbaum, Nivashni Murugan, Ming Tsai Chih, Oluwatosin Ayeni, Caroline Dickens, Katherine Crew, Judith S Jacobson, Alfred Neugut
PURPOSE: Breast conserving surgery (BCS) has become the preferred surgical option for the management of patients with nonmetastatic breast cancer in high-income countries. However, little is known about the distribution and determinants of BCS in low-and middle-income countries, especially those with high HIV prevalence. METHODS: We compared demographic and clinical characteristics of female patients who received BCS and those who received total mastectomy (TM) for nonmetastatic invasive carcinoma of the breast in Soweto, South Africa, 2009-2011...
2017: PloS One
https://www.readbyqxmd.com/read/28791541/cancer-counseling-of-low-income-limited-english-proficient-latina-women-using-medical-interpreters-implications-for-shared-decision-making
#8
Daniella Kamara, Jon Weil, Janey Youngblom, Claudia Guerra, Galen Joseph
In cancer genetic counseling (CGC), communication across language and culture challenges the model of practice based on shared decision-making. To date, little research has examined the decision-making process of low-income, limited English proficiency (LEP) patients in CGC. This study identified communication patterns in CGC sessions with this population and assessed how these patterns facilitate or inhibit the decision-making process during the sessions. We analyzed 24 audio recordings of CGC sessions conducted in Spanish via telephone interpreters at two public hospitals...
August 9, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28790867/cervical-cancer-screening-in-low-resource-settings-a-smartphone-image-application-as-an-alternative-to-colposcopy
#9
Caroline Gallay, Anne Girardet, Manuela Viviano, Rosa Catarino, Anne-Caroline Benski, Phuong Lien Tran, Christophe Ecabert, Jean-Philippe Thiran, Pierre Vassilakos, Patrick Petignat
BACKGROUND: Visual inspection after application of acetic acid (VIA) and Lugol's iodine (VILI) is a cervical cancer (CC) screening approach that has recently been adopted in low- and middle-income countries (LMIC). Innovative technologies allow the acquisition of consecutive cervical images of VIA and VILI using a smartphone application. The aim of this study was to evaluate the quality of smartphone images in order to assess the feasibility and usability of a mobile application for CC screening in LMIC...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28776606/special-needs-of-young-women-with-breast-cancer-in-limited-resource-settings
#10
Carmen Lizette Gálvez-Hernández, María Cecilia González-Robledo, Regina Barragán-Carrillo, Cynthia Villarreal-Garza
BACKGROUND: Young women with breast cancer (YWBC) comprise a group of patients with unique biopsychosocial characteristics with a special perception of needs throughout their disease and survivorship. Contexts marked by restricted allocations and economic constraints might further aggravate the struggle of these patients living within limited resource settings and can demand added requirements for them and their families. OBJECTIVE: To analytically explore the existing knowledge regarding the needs of YWBC in low- and middle- income countries (LMICs)...
July 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28776604/the-role-of-diet-physical-activity-body-fatness-and-breastfeeding-in-breast-cancer-in-young-women-epidemiological-evidence
#11
I Isabelle Romieu, A Amadou, V Chajes
The incidence of breast cancer (BC) is rising worldwide, with an increase in aggressive neoplasias in young women. Traditionally, BC in young women has been thought to be etiologically driven, primarily by genetic/hereditary factors. However, these factors explain only a small proportion of BCs, pointing to a role of the environment. Suspected factors responsible for this increase include lifestyle changes, notably alcohol consumption, diet with high intake of refined carbohydrates and saturated fat and low intake of polyunsaturated fatty acids (PUFA), fiber and vitamins (such as folate, vitamin D, and carotenoids), low physical activity, and body fatness, all of which may act from childhood and adolescent years through adulthood...
July 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28776284/breast-cancer-in-africa-prevalence-treatment-options-herbal-medicines-and-socioeconomic-determinants
#12
REVIEW
Kiven Erique Lukong, Yetunde Ogunbolude, Jean Paul Kamdem
Breast cancer is the leading cause of cancer-related deaths in women worldwide. GLOBOCAN estimated about 1.7 million new cases of breast cancer diagnoses worldwide and about 522,000 deaths in 2012. The burden of breast cancer mortality lies in the developing low-income and middle-income countries, where about 70% of such deaths occur. The incidence of breast cancer is also rising in low-income and middle-income countries in Africa as trend towards urbanization, and adoption of Western lifestyles increases. In general, the triple-negative breast cancer (TNBC) subtype tends to be frequent in women of African ancestry...
August 4, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28765069/prostate-cancer-screening-in-early-medicaid-expansion-states
#13
Jesse D Sammon, Emily C Serrell, Patrick Karabon, Jeffrey J Leow, Firas Abdollah, Joel S Weismann, Paul K J Han, Moritz Hansen, Mani Menon, Quoc-Dien Trinh
PURPOSE: The Affordable Care Act of 2010 included a provision to expand Medicaid by 2014. Six states and jurisdictions elected to expand Medicaid early, before 2012. This provided a natural experiment to test the association between expanded insurance coverage and preventive service utilization, including prostate cancer screening. METHODS: Using 2012 and 2014 Behavioral Risk Factor Surveillance System surveys, we identified men aged 40-64 years who reported prostate specific antigen (PSA) testing in the preceding 12 months...
July 29, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28763362/survival-after-primary-debulking-surgery-compared-with-neoadjuvant-chemotherapy-in-advanced-ovarian-cancer-a-national-cancer-database-study
#14
Brandon-Luke L Seagle, Stephen Graves, Anna E Strohl, Shohreh Shahabi
OBJECTIVE: The aim of this study was to compare overall survival (OS) of women with advanced ovarian cancer treated with primary debulking surgery (PDS) or neoadjuvant chemotherapy (NAC) using a large national cohort. METHODS: The 1998-2011 National Cancer Database was queried to identify women with stage III or IV ovarian cancer treated with multiagent chemotherapy and stage-appropriate surgery. Overall survival was estimated and compared using Kaplan-Meier analysis between women who received PDS followed by multiagent chemotherapy or NAC followed by interval surgery...
August 1, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28759883/challenges-to-the-census-international-trends-and-a-need-to-consider-public-health-benefits
#15
REVIEW
R T Wilson, S H Hasanali, M Sheikh, S Cramer, G Weinberg, A Firth, S H Weiss, C L Soskolne
The Canadian government decision to cancel the mandatory long-form census in 2010 (subsequently restored in 2015), along with similar discussions in the United Kingdom (UK) and the United States of America (USA), have brought the purpose and use of census data into focus for epidemiologists and public health professionals. Policy decision-makers should be well-versed in the public health importance of accurate and reliable census data for emergency preparedness planning, controlling disease outbreaks, and for addressing health concerns among vulnerable populations including the elderly, low-income, racial/ethnic minorities, and special residential groups (e...
July 28, 2017: Public Health
https://www.readbyqxmd.com/read/28756991/nutritional-status-of-breast-cancer-survivors-1-year-after-diagnosis-a-preliminary-analysis-from-the-malaysian-breast-cancer-survivorship-cohort-study
#16
Hazreen Abd Majid, Low Phei Keow, Tania Islam, Tin Tin Su, Marie Cantwell, Nur Aishah Taib
BACKGROUND: Lifestyle factors, such as diet, body weight, and physical activity, are linked to better survival after breast cancer (BC) diagnosis. A high percentage of the Malaysian population is overweight or obese. In addition, studies have shown a disparity in survival among Malaysian women compared with other higher-income countries. The Malaysian Breast Cancer Survivorship Cohort (MyBCC) study aims to study lifestyle factors that affect survival in BC survivors. These are the preliminary findings on the nutritional status of Malaysian BC survivors...
July 27, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28752364/socio-demographic-moderators-of-associations-between-psychological-factors-and-latinas-breast-cancer-screening-behaviors
#17
L G Perez, J P Elder, J Haughton, M E Martinez, E M Arredondo
This study tested whether socio-demographic factors moderated associations between psychological factors and Latinas' breast cancer screening behaviors. 222 churchgoing Latinas (40-65 years) in San Diego, CA completed surveys assessing socio-demographics (e.g., income and acculturation), psychological factors (e.g., perceived barriers to screening), and cancer screening behaviors. Multilevel models examined associations of socio-demographic and psychological factors (and their interactions) with adherence to annual mammography or clinical breast exam (CBE) screening...
July 27, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28749101/barriers-to-cervical-cancer-and-breast-cancer-screening-uptake-in-low-income-and-middle-income-countries-a-systematic-review
#18
Rakibul M Islam, Baki Billah, Md Nassif Hossain, John Oldroyd
Background: Cervical cancer (CCa) and breast cancer (BCa) are the two leading cancers in women worldwide. Early detection and education to promote early diagnosis and screening of CCa and BCa greatly increases the chances for successful treatment and survival. Screening uptake for CCa and BCa in low and middle - income countries (LMICs) is low, and is consequently failing to prevent these diseases. We conducted a systematic review to identify the key barriers to CCa and BCa screening in women in LMICs. Methods: We performed a systematic literature search using Ovid MEDLINE, EMBASE, PsycINFO, SCOPUS, CINHAL Plus, and Google scholar to retrieve all English language studies from inception to 2015...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28746576/quality-of-cervical-cancer-screening-in-brazil-external-assessment-of-the-pmaq
#19
Mara Rejane Barroso Barcelos, Rita de Cássia Duarte Lima, Elaine Tomasi, Bruno Pereira Nunes, Suele Manjourany Silva Duro, Luiz Augusto Facchini
OBJECTIVE: To examine whether demographic and socioeconomic variables and the variables of the organization of services are associated with the quality of cervical cancer screening. METHODS: This is a survey carried out in the health services of the five Brazilian regions in 2012. The sample consisted of users of basic health units participating in the Program for Improving Access and Quality of the Primary Care. The independent variables analyzed were: socioeconomic characteristics (municipal context), demographic characteristics (user profile), and two domains related to the organization of basic services (work structure and process)...
July 20, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28745394/opioids-for-chronic-non-cancer-pain-in-children-and-adolescents
#20
REVIEW
Tess E Cooper, Emma Fisher, Andrew L Gray, Elliot Krane, Navil Sethna, Miranda Al van Tilburg, Boris Zernikow, Philip J Wiffen
BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in children is a major public health concern of high significance in most parts of the world. While in the past, pain was largely dismissed and was frequently left untreated, views on children's pain have changed over time, and relief of pain is now seen as importantWe designed a suite of seven reviews on chronic non-cancer pain and cancer pain (looking at antidepressants, antiepileptic drugs, non-steroidal anti-inflammatory drugs, opioids, and paracetamol as priority areas) in order to review the evidence for children's pain utilising pharmacological interventions in children and adolescents...
July 26, 2017: Cochrane Database of Systematic Reviews
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