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https://www.readbyqxmd.com/read/28432588/patterns-of-care-and-outcomes-of-multi-agent-versus-single-agent-chemotherapy-as-part-of-multimodal-management-of-low-grade-glioma
#1
Waqar Haque, Vivek Verma, E Brian Butler, Bin S Teh
For high-risk low-grade gliomas (LGGs), adjuvant radiotherapy (RT) with procarbazine/lomustine/vincristine (PCV) chemotherapy increases overall survival (OS) over RT alone. However, in practice, temozolomide (TMZ) is often used instead of PCV. Using the National Cancer Data Base (NCDB), we provide the first investigation of practice patterns and outcomes of chemoradiotherapy with single-agent chemotherapy (SAC, analogous to TMZ) or multi-agent chemotherapy (MAC, analogous to PCV) for LGG. Patients with high-risk Grade II LGGs were queried in the NCDB...
April 21, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28427373/a-protocol-for-a-cluster-randomized-controlled-trial-of-a-self-help-psycho-education-programme-to-reduce-diagnosis-delay-in-women-with-breast-cancer-symptoms-in-indonesia
#2
Hari Setyowibowo, Marit Sijbrandij, Aulia Iskandarsyah, Joke A M Hunfeld, Sawitri S Sadarjoen, Dharmayanti F Badudu, Drajat R Suardi, Jan Passchier
BACKGROUND: Breast cancer (BC) is the most frequent cancer occurring in women across the world. Its mortality rate in low-middle income countries (LMICs) is higher than in high-income countries (HICs), and in Indonesia BC is the leading cause of cancer deaths among women. Delay in breast cancer diagnosis negatively impacts cancer prognosis. Only about 30% of patients who come to the hospital to check on their breast abnormalities, continue thorough examination to biopsy to get a diagnosis based on the results of anatomical pathology...
April 20, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28424832/setting-up-a-community-based-cervical-screening-service-in-a-low-income-country-a-pilot-study-from-north-western-tanzania
#3
Nestory Masalu, Patrizia Serra, Dino Amadori, Jackson Kahima, Charles Majinge, Joyce Rwehabura, Oriana Nanni, Sara Bravaccini, Maurizio Puccetti, Rosario Tumino, Lauro Bucchi
OBJECTIVES: To report the results of a pilot study for a service for cervical cancer screening and diagnosis in north-western Tanzania. METHODS: The pilot study was launched in 2012 after a community-level information campaign. Women aged 15-64 years were encouraged to attend the district health centres. Attendees were offered a conventional Pap smear and a visual inspection of the cervix with acetic acid (VIA). RESULTS: The first 2500 women were evaluated...
April 19, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28424766/the-need-for-hematology-nurse-education-in-low-and-middle-income-countries-a-community-case-study-in-tanzania
#4
Julie M Buser
Hematology-related diseases, such as anemia, malaria, sickle cell disease (SCD), and blood cancers, have differing rates of survival between high-income and low- and middle-income countries (LMICs). Nurses in LMICs have an unmet need for specialty training and education to address hematology and hemato-oncology disorders. A gap in the literature exists about hematology nurse education and clinical service demands in LMICs. This community case study documents a collaborative hematology and basic hemato-oncology education program to sustainably strengthen nurse capacity at a national referral hospital and university in Tanzania...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28423236/improvement-in-treatment-abandonment-in-pediatric-patients-with-cancer-in-guatemala
#5
Elysia Alvarez, Midori Seppa, Silvia Rivas, Lucia Fuentes, Patricia Valverde, Federico Antillón-Klussmann, Mauricio Castellanos, E Alejandro Sweet-Cordero, Kevin Messacar, John Kurap, Marisol Bustamante, Scott C Howard, Bradley Efron, Sandra Luna-Fineman
BACKGROUND: Treatment refusal and abandonment are major causes of treatment failure for children with cancer in low- and middle-income countries (LMICs), like Guatemala. This study identified risk factors for and described the intervention that decreased abandonment. METHODS: This was a retrospective study of Guatemalan children (0-18 years) with cancer treated at the Unidad Nacional de Oncología Pediátrica (UNOP), 2001-2008, using the Pediatric Oncology Network Database...
April 19, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28418767/randomized-controlled-trial-of-survivorship-care-plans-among-low-income-predominantly-latina-breast-cancer-survivors
#6
Rose C Maly, Li-Jung Liang, Yihang Liu, Jennifer J Griggs, Patricia A Ganz
Purpose The purpose of this study was to examine the effects of a randomized controlled trial (RCT) of treatment summaries and survivorship care plans coupled with a nurse counseling session, primarily on physician implementation of and secondarily on patient adherence to recommended survivorship care, among a low-income population of breast cancer survivors (survivors). Methods We recruited 212 low-income, predominantly Latina (72.6%) survivors with stage 0 to III breast cancer, with an average age of 53 years, from two Los Angeles County public hospitals into an RCT of a survivorship care nurse counseling session coupled with the provision of individualized treatment summaries and survivorship care plans to patients and their health care providers from December 2012 to July 2014...
April 18, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28415824/influence-of-marital-status-on-the-survival-of-adults-with-extrahepatic-intrahepatic-cholangiocarcinoma
#7
Zhiqiang Chen, Liyong Pu, Wen Gao, Long Zhang, Guoyong Han, Qin Zhu, Xiangcheng Li, Jindao Wu, Xuehao Wang
Although the prognostic value of marital status has been implicated in many cancers, its prognostic impact on cholangiocarcinoma has not yet been determined. The aim of this study was to examine the association between marital status and cholangiocarcinoma survival. We included 8,776 extrahepatic cholangiocarcinoma cases and 1,352 intrahepatic cholangiocarcinoma cases between 1973 and 2013 from the Surveillance, Epidemiology, and End Results database. We found widowed patients were more likely to be female, aged more than 70, and from low income areas...
March 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28408086/estimates-and-25-year-trends-of-the-global-burden-of-disease-attributable-to-ambient-air-pollution-an-analysis-of-data-from-the-global-burden-of-diseases-study-2015
#8
Aaron J Cohen, Michael Brauer, Richard Burnett, H Ross Anderson, Joseph Frostad, Kara Estep, Kalpana Balakrishnan, Bert Brunekreef, Lalit Dandona, Rakhi Dandona, Valery Feigin, Greg Freedman, Bryan Hubbell, Amelia Jobling, Haidong Kan, Luke Knibbs, Yang Liu, Randall Martin, Lidia Morawska, C Arden Pope, Hwashin Shin, Kurt Straif, Gavin Shaddick, Matthew Thomas, Rita van Dingenen, Aaron van Donkelaar, Theo Vos, Christopher J L Murray, Mohammad H Forouzanfar
BACKGROUND: Exposure to ambient air pollution increases morbidity and mortality, and is a leading contributor to global disease burden. We explored spatial and temporal trends in mortality and burden of disease attributable to ambient air pollution from 1990 to 2015 at global, regional, and country levels. METHODS: We estimated global population-weighted mean concentrations of particle mass with aerodynamic diameter less than 2·5 μm (PM2·5) and ozone at an approximate 11 km × 11 km resolution with satellite-based estimates, chemical transport models, and ground-level measurements...
April 10, 2017: Lancet
https://www.readbyqxmd.com/read/28400354/usability-of-a-novel-mobile-health-ipad-app-by-vulnerable-populations
#9
David P Miller, Kathryn E Weaver, L Doug Case, Donald Babcock, Donna Lawler, Nancy Denizard-Thompson, Michael P Pignone, John G Spangler
BACKGROUND: Recent advances in mobile technologies have created new opportunities to reach broadly into populations that are vulnerable to health disparities. However, mobile health (mHealth) strategies could paradoxically increase health disparities, if low socioeconomic status individuals lack the technical or literacy skills needed to navigate mHealth programs. OBJECTIVE: The aim of this study was to determine whether patients from vulnerable populations could successfully navigate and complete an mHealth patient decision aid...
April 11, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28393989/-factors-affecting-compliance-with-pap-smear-screening
#10
María Teresa Urrutia, Macarena Gajardo
BACKGROUND: Pap smear coverage in Chile has gradually decreased in the last years, from 67% to 59%, making it necessary to determine the causes of this decline. AIM: To analyze the relationship between the characteristics of the cervical cancer screening target population in the public health care system and the percentage of PAP coverage. MATERIAL AND METHODS: This study was carried out in women aged between 25 and 64 years, belonging to a public health care system and registered in any of the eight primary healthcare centers of a Metropolitan Santiago low income community...
December 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28393094/laparoscopic-surgery-for-gynecologic-cancer-in-low-and-middle-income-countries-lmics-an-area-of-need
#11
Melissa Schwartz, Cherng-Jye Jeng, Linus T Chuang
Over 90% of people living in low- and middle-income countries (LMICs) do not have access to surgical care. In the absence of appropriate surgical care, there is high morbidity and mortality from surgically curable diseases, such as cervical cancer. Laparoscopic surgery for gynecologic cancer in LMICs is extremely limited. The benefits of laparoscopy over open surgery are even more pronounced in LMICs than in resource-rich countries. Barriers to implementation of laparoscopic surgery in LMICs should be identified and addressed in order to improve global cancer care and the lives of women worldwide...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28386297/low-value-practices-in-oncology-contributing-to-financial-toxicity
#12
Bishal Gyawali
Financial toxicity of cancer treatment is now a well-recognised problem in cancer medicine leading to patient bankruptcy and even poor survival, including in high-income countries and countries with public health care systems. Many oncologists, despite acknowledging the severity of financial toxicity as a problem, resign the responsibility of reducing the costs of cancer treatment to the government, industry, and oncology societies. However, an oncologist can play an important role in reducing the costs of cancer treatment because all cancer treatment decisions are made between the oncologist and the patient...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28383806/socioeconomic-factors-and-survival-in-patients-with-non-metastatic-head-and-neck-squamous-cell-carcinoma
#13
Cheng Xu, Yu-Pei Chen, Xu Liu, Ling-Long Tang, Lei Chen, Yan-Ping Mao, Yuan Zhang, Rui Guo, Guan-Qun Zhou, Wen-Fei Li, Ai-Hua Lin, Ying Sun, Jun Ma
The effect of socioeconomic factors on receipt of definitive treatment and survival outcomes in non-metastatic head and neck squamous cell carcinoma (HNSCC) remains unclear. Eligible patients (n = 37,995) were identified from the United States Surveillance, Epidemiology and End Results (SEER) database between 2007 and 2012. Socioeconomic factors (i.e., median household income, education level, unemployment rate, insurance status, marital status and residence) were included in univariate/multivariate Cox regression analysis; validated factors were used to generate nomograms for cause-specific survival (CSS) and overall survival (OS), and a prognostic score model for risk stratification...
April 6, 2017: Cancer Science
https://www.readbyqxmd.com/read/28378959/the-impact-of-health-insurance-on-preventive-care-and-health-behaviors-evidence-from-the-first-two-years-of-the-aca-medicaid-expansions
#14
Kosali Simon, Aparna Soni, John Cawley
The U.S. population receives suboptimal levels of preventive care and has a high prevalence of risky health behaviors. One goal of the Affordable Care Act (ACA) was to increase preventive care and improve health behaviors by expanding access to health insurance. This paper estimates how the ACA-facilitated state-level expansions of Medicaid in 2014 affected these outcomes. Using data from the Behavioral Risk Factor Surveillance System, and a difference-in-differences model that compares states that did and did not expand Medicaid, we examine the impact of the expansions on preventive care (e...
2017: Journal of Policy Analysis and Management
https://www.readbyqxmd.com/read/28378254/colorectal-cancer-screening-compliance-among-asian-and-pacific-islander-americans
#15
Jermy-Leigh B Domingo, John J Chen, Kathryn L Braun
Colorectal cancer (CRC) screening prevalence remains low among Asians and Pacific Islanders. This study examined disparities and predictors of CRC screening compliance in adults age 50-75 years in Asians and Pacific Islanders in Hawai'i. Hawai'i Behavioral Risk Factor Surveillance System (BRFSS) data for 2011-2014 were analyzed. CRC screening status was dichotomized. Logistic regression was used to examine ethnic differences in and predictors of CRC screening status. Filipinos (OR 0.56), Chinese (OR 0.70), and Hawaiians (OR 0...
April 4, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28376438/those-left-behind-from-voluntary-medical-home-reforms-in-ontario-canada
#16
Tara Kiran, Alexander Kopp, Richard H Glazier
PURPOSE: Health systems are transitioning patients to medical homes to improve health outcomes and reduce cost. We sought to understand the characteristics and quality of care for patients who did and did not participate in the voluntary transition to medical homes. METHODS: We used administrative data for diabetes monitoring and cancer screening to compare services received by patients attached to a medical home (n = 10,785,687) with services received by those seeing a fee-for-service physician (n = 1,321,800) in Ontario, Canada, on March 31, 2011...
November 2016: Annals of Family Medicine
https://www.readbyqxmd.com/read/28374335/preventive-health-behaviors-among-low-income-african-american-and-hispanic-populations-can-colonoscopy-screening-serve-as-a-teachable-moment
#17
Pathu Sriphanlop, Lina Jandorf, Hayley Thompson, Heiddis Valdimarsdottir, William Redd, Rachel C Shelton
INTRODUCTION: Teachable moments (TMs) are situations with potential for promoting health behavior change. Little is known as to whether colonoscopy screening itself may serve as a TM, particularly among low-income or minority populations. Research in this area is needed to inform efforts to address the disproportionate burden of colorectal cancer (CRC) experienced by minorities. AIMS: This study aims to describe attitudes related to physical activity (PA) and healthy eating among a low-income Hispanic and African American sample, assess whether colonoscopy completion may encourage changes in dietary behavior or PA, and determine the type of interventions minority participants would prefer to promote preventive behaviors...
April 3, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28373252/factors-associated-with-participation-in-cervical-cancer-screening-among-young-koreans-a-nationwide-cross-sectional-study
#18
Ha Kyun Chang, Jun-Pyo Myong, Seung Won Byun, Sung-Jong Lee, Yong Seok Lee, Hae-Nam Lee, Keun Ho Lee, Dong Choon Park, Chan Joo Kim, Soo Young Hur, Jong Sup Park, Tae Chul Park
OBJECTIVES: Despite the possibility of early detection of cervical cancer, participation in screening programmes among young Koreans is low. We sought to identify associations between risk factors and participation in screening for cervical cancer among young Koreans. DESIGN: Nationwide cross-sectional study. SETTING: Republic of Korea. PARTICIPANTS: 3734. MAIN OUTCOME MEASURES: The Korea National Health and Nutrition Examination Survey (KNHANES V: 2010-2012) was used to evaluate factors associated with attendance for cervical cancer screening among women aged 15-39...
April 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28372963/2016-rad-aid-conference-on-international%C3%A2-radiology-for-developing-countries-gaps-growth-and-united-nations-sustainable-development-goals
#19
Daniel J Mollura, Garshasb Soroosh, Melissa P Culp
The 2016 RAD-AID Conference analyzed the accelerated global activity in the radiology community that is transforming medical imaging into an effective spearhead of health care capacity building in low- and middle-income countries. Global health efforts historically emphasized disaster response, crisis zones, and infectious disease outbreaks. However, the projected doubling of cancer and cardiovascular deaths in developing countries in the next 15 years and the need for higher technology screening and diagnostic technologies in low-resource regions, as articulated by the United Nations' new Sustainable Development Goals of 2016, is heightening the role of radiology in global health...
March 29, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28369405/cost-effectiveness-of-an-hpv-self-collection-campaign-in-uganda-comparing-models-for-delivery-of-cervical-cancer-screening-in-a-low-income-setting
#20
Nicole G Campos, Vivien Tsu, Jose Jeronimo, Denise Njama-Meya, Mercy Mvundura, Jane J Kim
With the availability of a low-cost HPV DNA test that can be administered by either a healthcare provider or a woman herself, programme planners require information on the costs and cost-effectiveness of implementing cervical cancer screening programmes in low-resource settings under different models of healthcare delivery. Using data from the START-UP demonstration project and a micro-costing approach, we estimated the health and economic impact of once-in-a-lifetime HPV self-collection campaign relative to clinic-based provider-collection of HPV specimens in Uganda...
February 20, 2017: Health Policy and Planning
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