keyword
MENU ▼
Read by QxMD icon Read
search

Renal failure and ART

keyword
https://www.readbyqxmd.com/read/27756893/first-left-hepatic-trisectionectomy-including-segment-one-with-new-associated-liver-partition-and-portal-vein-ligation-with-staged-hepatectomy-alpps-modification-how-to-do-it
#1
Aiman Obed, Anwar Jarrad, Abdalla Bashir
BACKGROUND Associated Liver Partition and Portal vein ligation with Staged hepatectomy (ALPPS) leads to rapid hepatic hypertrophy and decreases incidence of post-hepatectomy liver failure in patients with a marginal future liver remnant. Various procedural ALPPS modifications were previously described. Here, we present the first case of a new ALPPS modification, carrying out a left hepatic trisectionectomy with segment 1. CASE REPORT We present the case of a 36-year-old woman with locally advanced sigmoid adeno-carcinoma and extensive left liver metastases extending to segment V and VIII, who received state-of-the-art systemic conversion chemotherapy...
October 19, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27704056/endoureteral-management-of-renal-graft-ureteral-stenosis-by-the-use-of-long-term-metal-stent-an-appealing-treatment-option
#2
Patrick-Julien Treacy, Art R Rastinehad, Laetitia Imbert de la Phalecque, Laetitia Albano, Matthieu Durand
Background: Ureteral stenosis is part of the common complications of renal graft reported in 3% to 7% of cases. Multiple treatments have been introduced regarding length and position of the stenosis. Metal stents for urologic purpose were created in 1998. Double percutaneous antegrade and transurethral retrograde access to a ureteral stenosis to a long-term metal stent procedure has been rarely described. Case Presentation: Here, we present a case of a ureteral stricture in a double ipsilateral kidney graft with a common ureter...
2016: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/27647650/-andrologic-consequences-of-chronic-renal-failure-state-of-the-art-for-the-yearly-scientific-report-of-the-french-national-association-of-urology
#3
Y Neuzillet, R Thuret, F Kleinclauss, M-O Timsit
OBJECTIVE: To describe the state of the art of current knowledge regarding gonadal consequences of end-stage chronic kidney disease (CKD) and renal transplantation. MATERIAL AND METHOD: A systematic review of the literature search was performed from the databases Medline (NLM, Pubmed) and Embase, focused on the following keywords: "chronic kidney disease"; "chronic renal failure"; "hypogonadism"; "kidney transplantation"; "testicular dysfunction"; "testosterone"...
September 16, 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/27588613/dolutegravir-monotherapy-as-treatment-de-escalation-in-hiv-infected-adults-with-virological-control-dolumono-cohort-results
#4
Celia Oldenbuettel, Eva Wolf, Ayla Ritter, Sebastian Noe, Silke Heldwein, Rita Pascucci, Carmen Wiese, Ariane Von Krosigk, Eva Jaegel-Guedes, Hans Jaeger, Annamaria Balogh, Christine Koegl, Christoph D Spinner
BACKGROUND: The potential toxicity of long-term antiretroviral treatment (ART) requires ongoing investigation of novel strategies for treatment of HIV-infected patients. Monotherapy with the integrase inhibitor (INSTI) dolutegravir (DTG) may offer a favorable safety profile. Additionally, DTG has a high barrier of resistance, crucial for successful maintenance of virologic control. However, published data is sparse. METHODS: Retrospective, single-center cohort study...
September 2, 2016: Antiviral Therapy
https://www.readbyqxmd.com/read/27324472/nutritional-management-in-the-critically-ill-child-with-acute-kidney-injury-a-review
#5
Sidharth Kumar Sethi, Norma Maxvold, Timothy Bunchman, Pranaw Jha, Vijay Kher, Rupesh Raina
Acute kidney injury (AKI) in critically ill children is frequently a component of the multiple organ failure syndrome. It occurs within the framework of the severe catabolic phase determined by critical illness and is intensified by metabolic derangements. Nutritional support is a must for these children to improve outcomes. Meeting the special nutritional needs of these children often requires nutritional supplementation by either the enteral or the parenteral route. Since critically ill children with AKI comprise a heterogeneous group of subjects with varying nutrient needs, nutritional requirements should be frequently reassessed, individualized and carefully integrated with renal replacement therapy...
June 20, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/27237403/comparative-effectiveness-of-peripheral-vascular-intervention-versus-surgical-bypass-for-critical-limb-ischemia-in-the-vascular-study-group-of-greater-new-york
#6
Andrew J Meltzer, Art Sedrakyan, Abby Isaacs, Peter H Connolly, Darren B Schneider
OBJECTIVE: In this study, the effectiveness of peripheral vascular intervention (PVI) was compared with surgical bypass grafting (BPG) for critical limb ischemia (CLI) in the Vascular Study Group of Greater New York (VSGGNY). METHODS: Patients undergoing BPG or PVI for CLI at VSGGNY centers (2011-2013) were included. The Society for Vascular Surgery objective performance goals for CLI were used to directly compare the safety and effectiveness of PVI and BPG. Propensity score matching was used for risk-adjusted comparisons of PVI with BPG...
May 27, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27026330/the-role-of-biochemical-of-bone-turnover-markers-in-osteoporosis-and-metabolic-bone-disease-a-consensus-paper-of-the-belgian-bone-club
#7
E Cavalier, P Bergmann, O Bruyère, P Delanaye, A Durnez, J-P Devogelaer, S L Ferrari, E Gielen, S Goemaere, J-M Kaufman, A Nzeusseu Toukap, J-Y Reginster, A-F Rousseau, S Rozenberg, A J Scheen, J-J Body
The exact role of biochemical markers of bone turnover in the management of metabolic bone diseases remains a topic of controversy. In this consensus paper, the Belgian Bone Club aimed to provide a state of the art on the use of these biomarkers in different clinical or physiological situations like in postmenopausal women, osteoporosis in men, in elderly patients, in patients suffering from bone metastasis, in patients with chronic renal failure, in pregnant or lactating women, in intensive care patients, and in diabetics...
July 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27012265/coenzyme-q10-and-heart-failure-a-state-of-the-art-review
#8
REVIEW
Abhinav Sharma, Gregg C Fonarow, Javed Butler, Justin A Ezekowitz, G Michael Felker
Heart failure (HF) with either preserved or reduced ejection fraction is associated with increased morbidity and mortality. Evidence-based therapies are often limited by tolerability, hypotension, electrolyte disturbances, and renal dysfunction. Coenzyme Q10 (CoQ10) may represent a safe therapeutic option for patients with HF. CoQ10 is a highly lipophilic molecule with a chemical structure similar to vitamin K. Although being a common component of cellular membranes, CoQ10's most prominent role is to facilitate the production of adenosine triphosphate in the mitochondria by participating in redox reactions within the electron transport chain...
April 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/26985747/subclinical-rejection-in-renal-transplantation-reappraised
#9
Rajil Mehta, Puneet Sood, Sundaram Hariharan
Short-term outcomes in renal transplantation have improved significantly in the past few years. However, the improvement in long-term outcomes has been modest. The reasons for graft failure beyond the first year of transplantation have been attributed to several different factors. We believe that subclinical rejection (SCR) may be 1 of the factors that contribute to graft loss in the long run. We also believe that there are data to suggest that SCR leads to progressive fibrosis and loss of graft function. This has been demonstrated even in patients who have mild degrees of subclinical inflammation...
August 2016: Transplantation
https://www.readbyqxmd.com/read/26888910/dolutegravir-as-maintenance-monotherapy-first-experiences-in-hiv-1-patients
#10
Casper Rokx, Carolina A M Schurink, Charles A B Boucher, Bart J A Rijnders
BACKGROUND: Dolutegravir is recommended as part of combination ART (cART) for HIV-1-infected patients. Toxicities, drug interactions and costs related to cART still warrant the search for improved treatment options. Dolutegravir's high resistance barrier might make it suitable as antiretroviral maintenance monotherapy. The feasibility of this strategy is currently unknown. METHODS: This is a prospective case series on five consecutive HIV-1-infected patients on cART without previous virological failure who switched to dolutegravir monotherapy...
June 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/26839638/advances-in-hepatitis-c-therapy-what-is-the-current-state-what-come-s-next
#11
REVIEW
Steffen Zopf, Andreas E Kremer, Markus F Neurath, Juergen Siebler
Chronic hepatitis C virus (HCV) infection affects 80-160 million people worldwide and is one of the leading causes of chronic liver disease. It is only a few years ago that standard treatment regimes were based on pegylated interferon alpha and ribavirin. However, treatment of HCV has undergone a revolutionary change in recent years. The admission of the nucleotide polymerase inhibitor Sofosbuvir enabled an interferon-free regimen with direct antiviral agents (DAA). Meanwhile seven DAAs are available and can be applied in several combinations for 8 to 24 wk depending on HCV genotype and patient characteristics such as cirrhosis and chronic renal failure...
January 28, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/26636432/foscarnet-zidovudine-and-dolutegravir-combination-efficacy-and-tolerability-for-late-stage-hiv-salvage-therapy-a-case-series-experience
#12
Tristan Delory, Emmanuelle Papot, Christophe Rioux, Charlotte Charpentier, Claire Auge-Courtoi, Florence Michard, Gilles Peytavin, Diane Descamps, Sophie Matheron, Yazdan Yazdanpanah
Salvage therapy including foscarnet (PFA), zidovudine (ZDV) and an optimized background ART (OBT) has been shown to be effective in patients with advanced HIV infection, and no therapeutic options. Dolutegravir (DTG) may offer a more active combination. Objective was to describe efficacy and tolerability of PFA-ZDV-DTG containing regimen. In our cohort, we identified patients who: (i) had plasma HIV-1 RNA load (pVL) >50 c/ml (>100 for HIV-2) on combination ART (cART); (ii) had at least 1 PI/r, 1 NRTI, 1 NNRTI (for HIV-1), and at least 1 raltegravir resistance mutations; (iii) were naive to DTG; and (iv) initiated on a PFA-ZDV-DTG containing-regimen with 48 weeks (W48) of follow-up...
July 2016: Journal of Medical Virology
https://www.readbyqxmd.com/read/26375065/hem-3-trauma-organ-protection-with-artesunate-top-art-preclinical-efficacy-of-an-antimalarial-drug-with-excellent-safety-profile-and-planned-phase-ii-rct
#13
R Sordi, K K Nandra, F Chiazza, N S A Patel, K Brohi, M Collino, C Thiemermann
INTRODUCTION: Hemorrhagic shock (HS) is a common cause of death in severely injured patients and is associated with impairment of organ perfusion, systemic inflammatory response and multiple organ failure. The aim of the present study was to evaluate the effects of artesunate, the drug of choice for the treatment of falciparum malaria, on organ injury and dysfunction associated with HS in the rat. METHODS: Rats were subjected to HS. The arterial pressure was reduced to 30 mmHg for 90 min, followed by resuscitation with shed blood over 5 min...
October 2015: Shock
https://www.readbyqxmd.com/read/26309226/albuminuria-is-associated-with-traditional-cardiovascular-risk-factors-and-viral-load-in-hiv-infected-patients-in-rural-south-africa
#14
G Emerens Wensink, Annelot F Schoffelen, Hugo A Tempelman, Maarten B Rookmaaker, Andy I M Hoepelman, Roos E Barth
CONTEXT: As life expectancy improves among Human Immunodeficiency Virus (HIV) patients, renal and cardiovascular diseases are increasingly prevalent in this population. Renal and cardiovascular disease are mutual risk factors and are characterized by albuminuria. Understanding the interactions between HIV, cardiovascular risk factors and renal disease is the first step in tackling this new therapeutic frontier in HIV. METHODS: In a rural primary health care centre, 903 HIV-infected adult patients were randomly selected and data on HIV-infection and cardiovascular risk factors were collected...
2015: PloS One
https://www.readbyqxmd.com/read/26265463/safety-and-efficacy-of-combination-antiretroviral-therapy-in-human-immunodeficiency-virus-infected-adults-undergoing-autologous-or-allogeneic-hematopoietic-cell-transplantation-for-hematologic-malignancies
#15
COMPARATIVE STUDY
Christine Johnston, Robert Harrington, Rupali Jain, Joshua Schiffer, Hans-Peter Kiem, Ann Woolfrey
The ability to continue combination antiretroviral therapy (cART) in human immunodeficiency virus (HIV)-infected patients undergoing hematopoietic cell transplantation (HCT) for treatment of hematologic malignancies is likely a critical factor in preventing the establishment of an HIV reservoir in transplanted stem cells. Thus, we studied the feasibility of continued antiretroviral therapy in our HIV-infected patients undergoing autologous or allogeneic transplantation. All HIV-infected adults undergoing HCT for hematologic malignancy at Fred Hutchinson Cancer Research Center between 2006 and 2014 were included; most were enrolled in a prospective clinical study to monitor HIV reservoirs after transplantation (NCT00968630 and NCT00112593)...
January 2016: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/26176344/the-assure-study-hiv-1-suppression-is-maintained-with-bone-and-renal-biomarker-improvement-48-weeks-after-ritonavir-discontinuation-and-randomized-switch-to-abacavir-lamivudine%C3%A2-%C3%A2-atazanavir
#16
D A Wohl, L Bhatti, C B Small, H Edelstein, H H Zhao, D A Margolis, E DeJesus, W G Weinberg, L L Ross, M S Shaefer
OBJECTIVES: HIV treatment guidelines endorse switching or simplification of antiretroviral therapy in therapy-experienced patients with suppressed viraemia; ritonavir discontinuation may also enhance tolerability and reduce long-term adverse events (AEs). This open-label, multicentre, noninferiority study enrolled HIV-1-infected, treatment-experienced adults with confirmed HIV-1 RNA ≤ 75 HIV-1 RNA copies/mL currently receiving tenofovir/emtricitabine + atazanavir/ritonavir (TDF/FTC + ATV/r) for ≥ 6 months with no reported history of virological failure...
February 2016: HIV Medicine
https://www.readbyqxmd.com/read/26154924/towards-an-understanding-of-kidney-diseases-associated-with-wt1-mutations
#17
REVIEW
Lihua Dong, Stefan Pietsch, Christoph Englert
Mutations in Wilms' tumor 1 (WT1) cause a wide spectrum of renal manifestations, eventually leading to end-stage kidney failure. Insufficient understanding of WT1's molecular functions in kidney development has hampered efficient therapeutic applications for WT1-associated diseases. Recently, the generation and characterization of mouse models and application of multiple state-of-the-art approaches have significantly expanded our understanding of the molecular mechanisms of how WT1 mutations lead to kidney failure...
October 2015: Kidney International
https://www.readbyqxmd.com/read/26054327/autonomic-regulation-therapy-in-heart-failure
#18
REVIEW
Una Buckley, Kalyanam Shivkumar, Jeffrey L Ardell
Autonomic regulation therapy (ART) is a rapidly emerging therapy in the management of congestive heart failure secondary to systolic dysfunction. Modulation of the cardiac neuronal hierarchy can be achieved with bioelectronics modulation of the spinal cord, cervical vagus, baroreceptor, or renal nerve ablation. This review will discuss relevant preclinical and clinical research in ART for systolic heart failure. Understanding mechanistically what is being stimulated within the autonomic nervous system by such device-based therapy and how the system reacts to such stimuli is essential for optimizing stimulation parameters and for the future development of effective ART...
August 2015: Current Heart Failure Reports
https://www.readbyqxmd.com/read/26020949/risk-of-severe-non-aids-events-is-increased-among-patients-unable-to-increase-their-cd4-t-cell-counts-200-%C3%AE-l-despite-effective-haart
#19
Giuseppe Lapadula, Liliane Chatenoud, Andrea Gori, Francesco Castelli, Simona Di Giambenedetto, Massimiliano Fabbiani, Franco Maggiolo, Emanuele Focà, Nicoletta Ladisa, Laura Sighinolfi, Massimo Di Pietro, Angelo Pan, Carlo Torti
BACKGROUND: Immunological non-response (INR) despite virological suppression is associated with AIDS-defining events/death (ADE). Little is known about its association with serious non-AIDS-defining events (nADE). METHODS: Patients highly-active antiretroviral therapy (HAART) with <200 CD4+/μl and achieving HIV-RNA <50 copies/ml within 12 (±3) months were categorized as INR if CD4+ T-cell count at year 1 was <200/μl. Predictors of nADE (malignancies, severe infections, renal failure--ie, estimated glomerular filtration rate <30 ml/min, cardiovascular events and liver decompensation) were assessed using multivariable Cox models...
2015: PloS One
https://www.readbyqxmd.com/read/26013249/prevalence-and-pattern-of-chronic-kidney-disease-in-antiretroviral-na%C3%A3-ve-patients-with-hiv-aids
#20
Tewogbade Adeoye Adedeji, Nife O Adedeji, Simeon A Adebisi, Ademola A Idowu, Michael B Fawale, Kayode A Jimoh
BACKGROUND: Chronic renal failure and HIV/AIDS are both prevalent in Nigeria. We performed a cross-sectional analysis of renal function in newly diagnosed, treatment-naive HIV-infected patients before initiating highly active antiretroviral therapy. METHODS: Treatment-inexperienced individuals were recruited. Patients with diabetes mellitus and hypertension were excluded. Plasma creatinine level was used to measure the estimated glomerular filtration rate ([eGFR] by Modification of Diet in Renal Disease equation)...
September 2015: Journal of the International Association of Providers of AIDS Care
keyword
keyword
17866
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"