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https://www.readbyqxmd.com/read/28934802/intravertebral-vacuum-cleft-and-its-varied-locations-within-osteoporotic-vertebral-compression-fractures-effect-on-therapeutic-efficacy
#1
Weibo Yu, Xiaobing Jiang, De Liang, Zhensong Yao, Ting Qiu, Linqiang Ye, Shuncong Zhang, Daxiang Jin
BACKGROUND: Previous studies have reported a high incidence of re-collapse of the augmented vertebrae after percutaneous vertebral augmentation (PVA) for osteoporotic vertebral compression fractures (OVCFs) with intravertebral vacuum cleft (IVC) during long-term follow-up. Previous IVC might be considered an important predisposing factor for re-collapse, but the prior studies could not find a significant correlation. OBJECTIVE: To determine the incidence and distribution characteristics of IVCs and to further assess IVCs in their varied locations...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934789/lack-of-gender-and-age-differences-in-pain-measurements-following-exercise-in-people-with-chronic-whiplash-associated-disorders
#2
Kelly Ickmans, Anneleen Malfliet, Margot De Kooning, Lisa Goudman, Ives Hubloue, Tom Schmitz, Dorien Goubert, Maria Encarnacion Aguilar-Ferrandiz
BACKGROUND: Individuals with chronic whiplash associated disorders (WAD) present persistent pain in the absence of structural pathology. In these people, altered central pain processing and central sensitization are observed. The role of personal factors, such as gender and age, on pain processing mechanisms in chronic WAD, however, is still unclear. OBJECTIVES: This study investigated possible gender- and age-related differences in self-reported and experimental pain measurements in people with chronic WAD...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934715/stercoral-perforation-of-the-rectosigmoid-colon-due-to-chronic-constipation-a-case-report
#3
Mustafa Fevzi Celayir, Hakan Mustafa Köksal, Mehmet Uludag
INTRODUCTION: Chronic constipation is very common in elderly patients. As a result of this situation fecaloma is also frequently seen at these ages. However, the stercoral perforation caused by fecaloma is a rare situation to occur. The rectosigmoid colon is the most affected colonic segment. It is seen in older patients with concomitant diseases and a low quality of life. PRESENTATION OF CASE: Here in this case, we have to report an 83 - year-old male patient who came to the emergency room with complaints of abdominal pain and constipation for two days...
September 14, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28934665/venous-thromboembolism-in-children-with-cystic-fibrosis-retrospective-incidence-and-intrapopulation-risk-factors
#4
Jessica Knight-Perry, Brian R Branchford, Dianne Thornhill, Stacey L Martiniano, Scott D Sagel, Michael Wang
INTRODUCTION: Pediatric venous thromboembolism (VTE) is a rare but serious medical condition. Cystic fibrosis (CF) is a risk for recurrent pediatric VTE and has potential thrombophilic tendency. However, much remains unknown, including incidence and intrapopulation risk factors. METHODS: A retrospective cohort of pediatric CF patients followed at Children's Hospital Colorado from January 1st 2003 through May 20th 2016 was examined. Cases were identified by informatics and validated manually...
September 5, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28934636/museum-based-programs-for-socially-isolated-older-adults-understanding-what-works
#5
Carolyn Todd, Paul M Camic, Bridget Lockyer, Linda J M Thomson, Helen J Chatterjee
This paper presents research findings that help to understand how museum programs created opportunities to enhance wellbeing and health, and changed experiences of social isolation in older adults. The research conceptualized how program elements enabled both individual experiences and relational processes to occur. These components operated within a context that was enriched by the museum as a place to support wellbeing and enhance social interaction. To meaningfully support socially isolated older people as part of local public health strategies, museums need to be accessible and engaging places that purposively support social interaction by involving people and objects, participating in multiple sessions over time, that are facilitated by skilled and knowledgeable staff...
September 18, 2017: Health & Place
https://www.readbyqxmd.com/read/28934519/intra-pericardial-use-of-recombinant-factor-viia-in-a-patient-with-acute-hemorrhagic-pericardial-effusion-following-transcutaneous-aortic-valve-replacement-a-case-report
#6
Vanya Jaitly, Kimberly Klein, Hlaing Tint, Alice Chen, Paul Allison, Bindu Akkanti, Pranav Loyalka, Brian Castillo
Perioperative bleeding can be a serious life-threatening complication in adult patients undergoing cardiac surgery, given the older age and additional comorbidities present in this patient population. The standard treatment options include transfusion of blood components and surgical re-exploration. We report the first case of an elderly female patient treated with local administration of recombinant factor VIIa (rFVIIa) for intractable hemorrhagic pericardial effusion, which developed following a transcutaneous aortic valve replacement (TAVR) procedure for severe aortic stenosis...
August 1, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/28934461/effect-of-priming-with-seasonal-influenza-a-h3n2-virus-on-the-prevalence-of-cross-reactive-hemagglutination-inhibition-antibodies-to-swine-origin-a-h3n2-variants
#7
Feng Liu, Vic Veguilla, F Liaini Gross, Eric Gillis, Thomas Rowe, Xiyan Xu, Terrence M Tumpey, Jacqueline M Katz, Min Z Levine, Xiuhua Lu
Background: Recent outbreaks of swine-origin influenza A(H3N2) variant (H3N2v) viruses have raised public health concerns. Previous studies indicated that older children and young adults had the highest levels of hemagglutination-inhibition (HI) antibodies to 2010-2011 H3N2v viruses. However, newly emerging 2013 H3N2v have acquired antigenic mutations in the hemagglutinin at amino acid position 145 (N145K/R). We estimated the levels of serologic cross-reactivity among humans primed with seasonal influenza A(H3N2) (sH3N2), using postinfection ferret antisera...
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28934432/intestinal-damage-and-inflammatory-biomarkers-in-human-immunodeficiency-virus-hiv-exposed-and-hiv-infected-zimbabwean-infants
#8
Andrew J Prendergast, Bernard Chasekwa, Sandra Rukobo, Margaret Govha, Kuda Mutasa, Robert Ntozini, Jean H Humphrey
Background: Disease progression is rapid in human immunodeficiency virus (HIV)-infected infants. Whether intestinal damage and inflammation underlie mortality is unknown. Methods: We measured plasma intestinal fatty acid binding protein (I-FABP), soluble CD14 (sCD14), interleukin 6 (IL-6), and C-reactive protein (CRP) at 6 weeks and 6 months of age in 272 HIV-infected infants who either died (cases) or survived (controls), and in 194 HIV-exposed uninfected (HEU) and 197 HIV-unexposed infants...
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28934324/the-impact-of-community-based-palliative-care-on-acute-hospital-use-in-the-last-year-of-life-is-modified-by-time-to-death-age-and-underlying-cause-of-death-a-population-based-retrospective-cohort-study
#9
Katrina Spilsbury, Lorna Rosenwax, Glenn Arendts, James B Semmens
OBJECTIVE: Community-based palliative care is known to be associated with reduced acute care health service use. Our objective was to investigate how reduced acute care hospital use in the last year of life varied temporally and by patient factors. METHODS: A retrospective cohort study of the last year of life of 12,763 Western Australians who died from cancer or one of seven non-cancer conditions. Outcome measures were rates of hospital admissions and mean length of hospital stays...
2017: PloS One
https://www.readbyqxmd.com/read/28934309/increased-plasma-proline-concentrations-are-associated-with-sarcopenia-in-the-elderly
#10
Kenji Toyoshima, Marie Nakamura, Yusuke Adachi, Akira Imaizumi, Tomomi Hakamada, Yasuko Abe, Eiji Kaneko, Soiciro Takahashi, Kentaro Shimokado
BACKGROUND AND PURPOSE: Metabolome analyses have shown that plasma amino acid profiles reflect various pathological conditions, such as cancer and diabetes mellitus. It remains unclear, however, whether plasma amino acid profiles change in patients with sarcopenia. This study therefore aimed to investigate whether sarcopenia-specific changes occur in plasma amino acid profiles. METHODS: A total of 153 community-dwelling and seven institutionalized elderly individuals (56 men, 104 women; mean age, 77...
2017: PloS One
https://www.readbyqxmd.com/read/28934306/causes-of-delay-in-door-to-balloon-time-in-south-east-asian-patients-undergoing-primary-percutaneous-coronary-intervention
#11
Wen Jun Sim, An Shing Ang, Mae Chyi Tan, Wen Wei Xiang, David Foo, Kwok Kong Loh, Fahim Haider Jafary, Timothy James Watson, Paul Jau Lueng Ong, Hee Hwa Ho
OBJECTIVE: To evaluate causes and impact of delay in the door-to-balloon (D2B) time for patients undergoing primary percutaneous coronary intervention (PPCI). SUBJECTS AND METHODS: From January 2009 to December 2012, 1268 patients (86% male, mean age of 58 ± 12 years) presented to our hospital for ST-elevation myocardial infarction (STEMI) and underwent PPCI. They were divided into two groups: Non-delay defined as D2B time ≤ 90 mins and delay group defined as D2B time > 90 mins...
2017: PloS One
https://www.readbyqxmd.com/read/28934242/twelve-years-of-chiari-like-malformation-and-syringomyelia-scanning-in-cavalier-king-charles-spaniels-in-the-netherlands-towards-a-more-precise-phenotype
#12
Katrien Wijnrocx, Leonie W L Van Bruggen, Wieteke Eggelmeijer, Erik Noorman, Arnold Jacques, Nadine Buys, Steven Janssens, Paul J J Mandigers
Chiari-like malformation (CM), syringomyelia (SM) and middle ear effusion (also called PSOM) are three conditions that frequently occur in Cavalier King Charles Spaniels (CKCS). Both CM and SM are currently screened in the Netherlands prior to breeding and are graded according to the British Veterinary Association's Kennel Club (BVA/KC) scheme. This study evaluated the prevalence and estimated genetic parameter of CM, SM and middle ear effusion from 12 years of screening results. For SM, the classical method using the BVA/KC scheme, was compared with exact measuring of the central canal dilation...
2017: PloS One
https://www.readbyqxmd.com/read/28934233/cardiovascular-disease-and-mortality-after-breast-cancer-in-postmenopausal-women-results-from-the-women-s-health-initiative
#13
Na-Jin Park, Yuefang Chang, Catherine Bender, Yvette Conley, Rowan T Chlebowski, G J van Londen, Randi Foraker, Sylvia Wassertheil-Smoller, Marcia L Stefanick, Lewis H Kuller
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among older postmenopausal women. The impact of postmenopausal breast cancer on CVD for older women is uncertain. We hypothesized that older postmenopausal women with breast cancer would be at a higher risk of CVD than similar aged women without breast cancer and that CVD would be a major contributor to the subsequent morbidity and mortality. METHODS: In a prospective Women's Health Initiative study, incident CVD events and total and cause-specific death rates were compared between postmenopausal women with (n = 4,340) and without (n = 97,576) incident invasive breast cancer over 10 years post-diagnosis, stratified by 3 age groups (50-59, 60-69, and 70-79)...
2017: PloS One
https://www.readbyqxmd.com/read/28934192/metabolomics-and-cognition-in-african-american-adults-in-midlife-the-atherosclerosis-risk-in-communities-study
#14
J Bressler, B Yu, T H Mosley, D S Knopman, R F Gottesman, A Alonso, A R Sharrett, L M Wruck, E Boerwinkle
Clinical studies have shown alterations in metabolic profiles when patients with mild cognitive impairment and Alzheimer's disease dementia were compared to cognitively normal subjects. Associations between 204 serum metabolites measured at baseline (1987-1989) and cognitive change were investigated in 1035 middle-aged community-dwelling African American participants in the biracial Atherosclerosis Risk in Communities (ARIC) Study. Cognition was evaluated using the Delayed Word Recall Test (DWRT; verbal memory), the Digit Symbol Substitution Test (DSST; processing speed) and the Word Fluency Test (WFT; verbal fluency) at visits 2 (1990-1992) and 4 (1996-1998)...
July 18, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28934191/effects-of-aerobic-exercise-on-brain-metabolism-and-grey-matter-volume-in-older-adults-results-of-the-randomised-controlled-smart-trial
#15
S Matura, J Fleckenstein, R Deichmann, T Engeroff, E Füzéki, E Hattingen, R Hellweg, B Lienerth, U Pilatus, S Schwarz, V A Tesky, L Vogt, W Banzer, J Pantel
There is mounting evidence that aerobic exercise has a positive effect on cognitive functions in older adults. To date, little is known about the neurometabolic and molecular mechanisms underlying this positive effect. The present study used magnetic resonance spectroscopy and quantitative MRI to systematically explore the effects of physical activity on human brain metabolism and grey matter (GM) volume in healthy aging. This is a randomised controlled assessor-blinded two-armed trial (n=53) to explore exercise-induced neuroprotective and metabolic effects on the brain in cognitively healthy older adults...
July 18, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28934150/frailty-and-its-contributory-factors-in-older-adults-a-comparison-of-two-asian-regions-hong-kong-and-taiwan
#16
Ruby Yu, Wan-Chi Wu, Jason Leung, Susan C Hu, Jean Woo
This study aimed to compare the prevalence of frailty across three Chinese populations: Hong Kong, Taiwan-urban and Taiwan-rural. Contributing factors to disparities in frailty were also examined. Data were derived from the Osteoporotic Fractures in Men (MrOs) and Women (MsOs) (Hong Kong) Study (n = 4000) and the Taiwan Longitudinal Study on Aging (n = 2392). Frailty was defined as an index calculated from 30 multiple deficits. The ratio of the frailty index to life expectancy at birth (FI/LE) was used as an indicator of compression of morbidity...
September 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28934110/a-recombinant-measles-vaccine-with-enhanced-resistance-to-passive-immunity
#17
Emily Julik, Jorge Reyes-Del Valle
Current measles vaccines suffer from poor effectiveness in young infants due primarily to the inhibitory effect of residual maternal immunity on vaccine responses. The development of a measles vaccine that resists such passive immunity would strongly contribute to the stalled effort toward measles eradication. In this concise communication, we show that a measles virus (MV) with enhanced hemagglutinin (H) expression and incorporation, termed MVvac2-H2, retained its enhanced immunogenicity, previously established in older mice, when administered to very young, genetically modified, MV-susceptible mice in the presence of passive anti-measles immunity...
September 21, 2017: Viruses
https://www.readbyqxmd.com/read/28934079/direct-marketing-promotion-and-electronic-cigarette-use-among-us-adults-national-adult-tobacco-survey-2013-2014
#18
Hongying Dai, Jianqiang Hao
INTRODUCTION: The use of electronic cigarettes (e-cigarettes) among US adults has increased since 2007. The objective of this study was to investigate the prevalence of direct marketing promotion of e-cigarettes and its association with e-cigarette use among US adults. METHODS: We used using data from the 2013-2014 National Adult Tobacco Survey (NATS) to estimate prevalence of e-cigarette promotions received by mail or email. Multinomial logistic regression was used to examine the associations between e-cigarette promotions and the prevalence and frequency of e-cigarette use among US adults...
September 21, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28934075/gerontological-education-course-and-experiential-differences-across-academic-colleges
#19
Hardeep K Obhi, Jennifer A Margrett, Yan Su, Sarah L Francis, Young-A Lee, Denise A Crawford, Warren D Franke
A knowledgeable workforce is key to meeting the demands of an aging population that is expected to nearly triple by 2030 and attitudes influence propensity to seek aging-related careers. Post-secondary education offers an opportunity to increase aging-related knowledge and facilitates intergenerational experiential-learning opportunities; however, research is lacking regarding attitudes towards aging and experiences among an academically diverse sample. To address this gap, the aims of this study were to: (1) examine differences in students' attitudes toward older adults by academic college; (2) assess differences in aging-related coursework and course experiences by academic college; and (3) explore key factors associated with students' attitudes toward older adults...
September 21, 2017: Gerontology & Geriatrics Education
https://www.readbyqxmd.com/read/28933993/gradual-physical-decline-characterises-the-illness-trajectories-of-care-home-residents
#20
Anne M Finucane, Barbara Stevenson, Scott A Murray
BACKGROUND: Three archetypal trajectories of physical decline have been identified: a short period of rapid decline; long-term limitations with intermittent acute periods; and a prolonged gradual decline. An understanding of illness trajectories can help clarify the evolving needs of people with progressive conditions, and inform the development of palliative care services to meet their needs. Many frail older people live and die in care homes; the present study is the first to explore the illness trajectories of residents in care home settings...
September 2, 2017: International Journal of Palliative Nursing
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