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https://www.readbyqxmd.com/read/28944855/integrated-mrnaseq-and-micrornaseq-data-analysis-for-grade%C3%A2-iii-gliomas
#1
Junqiang Dai, Zhitong Bing, Yinian Zhang, Qiao Li, Liang Niu, Wentao Liang, Guoqiang Yuan, Lei Duan, Hang Yin, Yawen Pan
The World Health Organization classification distinguishes four grades for gliomas. Grade III gliomas, which are brain malignant brain tumors with variable biological behavior and propensity, have been not widely investigated. The objective of the present study was to identify specific gene modules and valuable hubs associated with gliomagenesis and molecular signatures to assist in determining grade III glioma prognosis. mRNAseq and micro (mi)RNAseq data were used to construct a co‑expression network of gliomas using weight gene co‑expression network analysis, and revealed the prognostic molecular signature of grade III gliomas...
September 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944813/transparent-amorphous-strontium-titanate-resistive-memories-with-transient-photo-response
#2
Taimur Ahmed, Sumeet Walia, Jeeson Kim, Hussein Nili, Rajesh Ramanathan, Edwin L H Mayes, Desmond W M Lau, Omid Kavehei, Vipul Bansal, Madhu Bhaskaran, Sharath Sriram
Transparent non-volatile memory devices are desirable for realizing visually-clear integrated systems for information storage. Optical transparency provides advantages in applications such as smart glass electronic devices and wearable electronics. However, achieving high transparency limits the choice of active layers as well as the electrodes; thereby, constraining device processing and performance. Here, we demonstrate bilayer transparent memory cells using room temperature deposited amorphous strontium titanate as the functional material and indium tin oxide electrodes...
September 25, 2017: Nanoscale
https://www.readbyqxmd.com/read/28944474/altered-neural-oscillations-during-multisensory-integration-in-adolescents-with-fetal-alcohol-spectrum-disorder
#3
Alfredo D Bolaños, Brian A Coffman, Felicha T Candelaria-Cook, Piyadasa Kodituwakku, Julia M Stephen
BACKGROUND: Children with fetal alcohol spectrum disorder (FASD), who were exposed to alcohol in utero, display a broad range of sensory, cognitive, and behavioral deficits, which are broadly theorized to be rooted in altered brain function and structure. Based on the role of neural oscillations in multisensory integration from past studies, we hypothesized that adolescents with FASD would show a decrease in oscillatory power during event-related gamma oscillatory activity (30-100Hz), when compared to typically-developing healthy controls (HC), and that such decrease in oscillatory power would predict behavioral performance...
September 25, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28943814/helping-children-cope-with-medical-tests-and-interventions
#4
Elvira V Lang, Jacqueline Viegas, Chris Bleeker, Jörgen Bruhn, Geffen Geert-Jan van
Medical procedures and tests become a challenge when anxiety and pain make it difficult for the patient to cooperate or remain still when needed. Fortunately a short intervention with hypnoidal language at the onset of a procedure induces a positive and sustained change in the way pain and anxiety are processed. While anesthesia may appear to be a simple solution to eliminate pain, the adverse effects of pre-anesthesia anxiety on postoperative behavior and recovery are often not fully appreciated. This paper discusses options for self-hypnotic relaxation that are applicable to interactions with children...
March 2017: Journal of Radiology Nursing
https://www.readbyqxmd.com/read/28943707/burning-down-the-silos-integrating-new-perspectives-from-the-social-sciences-into-human-behavior-in-fire-research
#5
Erica Kuligowski
The traditional social science disciplines can provide many benefits to the field of human behavior in fire (HBiF). First, the social sciences delve further into insights only marginally examined by HBiF researchers, in turn, expanding the depth of HBiF research. In this paper, I present examples of studies from the fields of social psychology and sociology that would expand HBiF research into non-engineering or "unobservable" aspects of behavior during a fire event. Second, the social sciences can provide insight into new areas of research; in turn, expanding the scope of HBiF research...
August 2017: Fire Mater
https://www.readbyqxmd.com/read/28943200/determinants-of-the-overuse-of-imaging-in-low-risk-prostate-cancer-a-systematic-review
#6
REVIEW
Allison H Oakes, Ritu Sharma, Madeline Jackson, Jodi B Segal
BACKGROUND: The overuse of radiologic services, where imaging tests are provided in circumstances where the propensity for harm exceeds the propensity for benefit, comprises a risk to patient safety and a burden on health care systems. Advanced imaging in the staging of low-risk prostate cancer is considered an overused procedure by many professional societies, yet the determinants that drive this phenomenon are not fully appreciated. METHODS: We systematically searched published literature within MEDLINE and Embase from January 1998 to March 2017...
September 21, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28941767/a-proton-mr-spectroscopy-study-of-the-thalamus-in-twins-with-autism-spectrum-disorder
#7
John P Hegarty, Meng Gu, Daniel M Spielman, Sue C Cleveland, Joachim F Hallmayer, Laura C Lazzeroni, Mira M Raman, Thomas W Frazier, Jennifer M Phillips, Allan L Reiss, Antonio Y Hardan
Multiple lines of research have reported thalamic abnormalities in individuals with autism spectrum disorder (ASD) that are associated with social communication impairments (SCI), restricted and repetitive behaviors (RRB), or sensory processing abnormalities (SPA). Thus, the thalamus may represent a common neurobiological structure that is shared across symptom domains in ASD. Same-sex monozygotic (MZ) and dizygotic (DZ) twin pairs with and without ASD underwent cognitive/behavioral evaluation and magnetic resonance imaging to assess the thalamus...
September 20, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28940867/gray-matter-volumes-of-early-sensory-regions-are-associated-with-individual-differences-in-sensory-processing
#8
Sayaka Yoshimura, Wataru Sato, Takanori Kochiyama, Shota Uono, Reiko Sawada, Yasutaka Kubota, Motomi Toichi
Sensory processing (i.e., the manner in which the nervous system receives, modulates, integrates, and organizes sensory stimuli) is critical when humans are deciding how to react to environmental demands. Although behavioral studies have shown that there are stable individual differences in sensory processing, the neural substrates that implement such differences remain unknown. To investigate this issue, structural magnetic resonance imaging scans were acquired from 51 healthy adults and individual differences in sensory processing were assessed using the Sensory Profile questionnaire (Brown et al...
September 20, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28939545/protocol-for-co-design-development-and-open-trial-of-a-prototype-game-based-ehealth-intervention-to-treat-anxiety-in-young-people-with-long-term-physical-conditions
#9
Hiran Thabrew, Karolina Stasiak, Sally Merry
BACKGROUND: Approximately 10% to 12% of New Zealand young people (and 21% of Maori young people) have long-term physical conditions and are more likely to develop psychological problems, particularly anxiety and depression. Delayed treatment leads to worse management of physical conditions, school absence, and poorer long-term outcomes. Recently, electronic health (eHealth) interventions have been shown to be as good as face-to-face therapy and biofeedback techniques have been shown to enhance relaxation during the treatment of anxiety...
September 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28939347/optimal-construction-of-army-ant-living-bridges
#10
Jason M Graham, Albert B Kao, Dylana A Wilhelm, Simon Garnier
Integrating the costs and benefits of collective behaviors is a fundamental challenge to understanding the evolution of group living. These costs and benefits can rarely be quantified simultaneously due to the complexity of the interactions within the group, or even compared to each other because of the absence of common metrics between them. The construction of 'living bridges' by New World army ants - which they use to shorten their foraging trails - is a unique example of a collective behavior where costs and benefits have been experimentally measured and related to each other...
September 19, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28939008/an-improved-procedure-for-integrated-behavioral-z-scoring-illustrated-with-modified-hole-board-behavior-of-male-inbred-laboratory-mice
#11
M Maaike Labots, M C Marijke Laarakker, D Dustin Schetters, S S Saskia Arndt, H A Hein van Lith
BACKGROUND: Guilloux et al. introduced: integrated behavioral z-scoring, a method for behavioral phenotyping of mice. Using this method multiple ethological variables can be combined to show an overall description of a certain behavioral dimension or motivational system. However, a problem may occur when the control group used for the calculation has a standard deviation of zero or when no control group is present to act as a reference group. NEW METHOD: In order to solve these problems, an improved procedure is suggested: taking the pooled data as reference...
September 19, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28938848/differences-in-how-mothers-and-fathers-monitor-sugar-sweetened-beverages-for-their-young-children-7-12-years
#12
Paul Branscum, Alexandra Housely
The purpose of this study was to evaluate differences between how mothers and fathers monitor their children's sugar-sweetened beverages (SSBs; 7-12 years) using constructs from the integrated behavioral model (IBM). Mothers ( n = 167) and fathers ( n = 117) completed a valid and reliable survey evaluating the extent that they monitored their child's SSB intake and constructs of the IBM. Results showed significant differences between groups, with mothers consistently having higher levels of monitoring SSBs and IBM constructs...
September 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28938181/cortical-inhibitory-interneurons-control-sensory-processing
#13
REVIEW
Katherine C Wood, Jennifer M Blackwell, Maria Neimark Geffen
Inhibitory and excitatory neurons form intricate interconnected circuits in the mammalian sensory cortex. Whereas the function of excitatory neurons is largely to integrate and transmit information within and between brain areas, inhibitory neurons are thought to shape the way excitatory neurons integrate information, and they exhibit context-specific and behavior-specific responses. Over the last few years, work across sensory modalities has begun unraveling the function of distinct types of cortical inhibitory neurons in sensory processing, identifying their contribution to controlling stimulus selectivity of excitatory neurons and modulating information processing based on the behavioral state of the subject...
September 19, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28937978/a-new-discrete-dynamic-model-of-aba-induced-stomatal-closure-predicts-key-feedback-loops
#14
Réka Albert, Biswa R Acharya, Byeong Wook Jeon, Jorge G T Zañudo, Mengmeng Zhu, Karim Osman, Sarah M Assmann
Stomata, microscopic pores in leaf surfaces through which water loss and carbon dioxide uptake occur, are closed in response to drought by the phytohormone abscisic acid (ABA). This process is vital for drought tolerance and has been the topic of extensive experimental investigation in the last decades. Although a core signaling chain has been elucidated consisting of ABA binding to receptors, which alleviates negative regulation by protein phosphatases 2C (PP2Cs) of the protein kinase OPEN STOMATA 1 (OST1) and ultimately results in activation of anion channels, osmotic water loss, and stomatal closure, over 70 additional components have been identified, yet their relationships with each other and the core components are poorly elucidated...
September 22, 2017: PLoS Biology
https://www.readbyqxmd.com/read/28937914/collective-psychological-ownership-and-intergroup-relations
#15
Maykel Verkuyten, Borja Martinovic
Whereas much social psychological research has studied the in-group and out-group implications of social categorization and collective identity ("we"), little research has examined the nature and relevance of collective psychological ownership ("ours") for intergroup relations. We make a case for considering collective psychological ownership as an important source of intergroup tensions. We do so by integrating theory and research from various social sciences, and we draw out implications for future social psychological research on intergroup relations...
September 1, 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28937316/age-dependent-responses-of-brain-myelin-integrity-and-behavioral-performance-to-radiation-in-mice
#16
Zhimeng Fu, Yunfei Zhao, Kaixiang Zhang, Jian Wang, Min Zhang, Xianghui Zhao
Radiation therapy is widely used to treat primary and metastatic brain tumors, but it may also lead to delayed neurological complications. Oligodendrocytes in the central nervous system produce myelin, and myelin integrity becomes highly vulnerable after brain irradiation. In this study, mice at different developmental stages were used to test the age-dependent sensitivity of myelin formation and maintenance, as well as behavioral performance after whole-brain irradiation (WBI). Mice at postnatal days 21 and 28 and at 2 months received a single dose of 25 Gy WBI...
September 22, 2017: Radiation Research
https://www.readbyqxmd.com/read/28937205/electrospun-p-type-nickel-oxide-semiconducting-nanowires-for-low-voltage-field-effect-transistors
#17
Ao Liu, You Meng, Huihui Zhu, Yong-Young Noh, Guoxia Liu, Fukai Shan
One-dimensional metal-oxide nanowires are regarded as important building blocks in nanoscale electronics due to their unique mechanical and electrical properties. In this work, p-type nickel oxide nanowires (NiO NWs) were fabricated by combining sol-gel and electrospinning processes. The polyvinylpyrrolidone (PVP) with 1,300,000 molecular weight was used as the polymer matrix to increase the viscosity of NiO precursor solution. The formation and properties of the as-spun NiO/PVP composite NWs before/after calcination treatment were investigated using various techniques...
September 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28937173/adsorption-of-molecular-hydrogen-on-coronene-with-a-new-potential-energy-surface
#18
Massimiliano Bartolomei, Ricardo Pérez de Tudela, Kilian Arteaga, Tomás González-Lezana, Marta I Hernández, José Campos-Martínez, Pablo Villarreal, Javier Hernández-Rojas, José Bretón, Fernando Pirani
Benchmark interaction energies between coronene, C24H12, and molecular hydrogen, H2, have been computed by means of high level electronic structure calculations. Binding energies, equilibrium distances and strengths of the long range attraction, evaluated for the basic configurations of the H2-C24H12 complex, indicate that the system is not too affected by the relative orientations of the diatom, suggesting that its behavior can be approximated to that of a pseudoatom. The obtained energy profiles have confirmed the noncovalent nature of the bonding and serve to tune-up the parameters of a new force field based on the atom-bond approach which correctly describes the main features of the H2-coronene interaction...
September 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28935692/probing-structure-function-relationships-in-early-events-in-photosynthesis-using-a-chimeric-photocomplex
#19
Kenji V P Nagashima, Mai Sasaki, Kanako Hashimoto, Shinichi Takaichi, Sakiko Nagashima, Long-Jiang Yu, Yuto Abe, Kenta Gotou, Tomoaki Kawakami, Mizuki Takenouchi, Yuuta Shibuya, Akira Yamaguchi, Takashi Ohno, Jian-Ren Shen, Kazuhito Inoue, Michael T Madigan, Yukihiro Kimura, Zheng-Yu Wang-Otomo
The native core light-harvesting complex (LH1) from the thermophilic purple phototrophic bacterium Thermochromatium tepidum requires Ca(2+) for its thermal stability and characteristic absorption maximum at 915 nm. To explore the role of specific amino acid residues of the LH1 polypeptides in Ca-binding behavior, we constructed a genetic system for heterologously expressing the Tch. tepidum LH1 complex in an engineered Rhodobacter sphaeroides mutant strain. This system contained a chimeric pufBALM gene cluster (pufBA from Tch...
September 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28935225/heart-rate-variability-biofeedback-and-other-psychophysiological-procedures-as-important-elements-in-psychotherapy
#20
REVIEW
Paul Lehrer
Lang's distinction of psychophysiological, behavioral, and cognitive domains in psychological problems and therapies provides a useful heuristic for guiding psychotherapy. Much psychotherapy practice emphasizes the cognitive domain, but behavioral and psychophysiological interventions show at least equivalent effectiveness for some kinds of problems. Most descriptions of cognitive behavior therapy emphasize cognitive procedures, although most CBT approaches also incorporate behavioral interventions such as social skills training, exposure, and behavior activation...
September 18, 2017: International Journal of Psychophysiology
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