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Elizabeth M Jaffee, Chi Van Dang, David B Agus, Brian M Alexander, Kenneth C Anderson, Alan Ashworth, Anna D Barker, Roshan Bastani, Sangeeta Bhatia, Jeffrey A Bluestone, Otis Brawley, Atul J Butte, Daniel G Coit, Nancy E Davidson, Mark Davis, Ronald A DePinho, Robert B Diasio, Giulio Draetta, A Lindsay Frazier, Andrew Futreal, Sam S Gambhir, Patricia A Ganz, Levi Garraway, Stanton Gerson, Sumit Gupta, James Heath, Ruth I Hoffman, Cliff Hudis, Chanita Hughes-Halbert, Ramy Ibrahim, Hossein Jadvar, Brian Kavanagh, Rick Kittles, Quynh-Thu Le, Scott M Lippman, David Mankoff, Elaine R Mardis, Deborah K Mayer, Kelly McMasters, Neal J Meropol, Beverly Mitchell, Peter Naredi, Dean Ornish, Timothy M Pawlik, Jeffrey Peppercorn, Martin G Pomper, Derek Raghavan, Christine Ritchie, Sally W Schwarz, Richard Sullivan, Richard Wahl, Jedd D Wolchok, Sandra L Wong, Alfred Yung
We are in the midst of a technological revolution that is providing new insights into human biology and cancer. In this era of big data, we are amassing large amounts of information that is transforming how we approach cancer treatment and prevention. Enactment of the Cancer Moonshot within the 21st Century Cures Act in the USA arrived at a propitious moment in the advancement of knowledge, providing nearly US$2 billion of funding for cancer research and precision medicine. In 2016, the Blue Ribbon Panel (BRP) set out a roadmap of recommendations designed to exploit new advances in cancer diagnosis, prevention, and treatment...
November 2017: Lancet Oncology
Brenda Leung, Romy Lauche, Matthew Leach, Yan Zhang, Holger Cramer, David Sibbritt
BACKGROUND: Special diets are frequently used by the public but reasons for use and characteristics of users remain unclear. AIM: To determine prevalence of the use of special diets, the individual characteristics associated with their use and reasons for use. METHODS: The secondary analysis used data from the 2012 National Health Interview Survey (NHIS), a cross-sectional household interview survey of a nationally representative sample of non-hospitalized US adult populations ( n = 34,525)...
March 2018: Nutrition and Health
Stephen D Anton, Azumi Hida, Kacey Heekin, Kristen Sowalsky, Christy Karabetian, Heather Mutchie, Christiaan Leeuwenburgh, Todd M Manini, Tracey E Barnett
The present review examined the evidence base for current popular diets, as listed in the 2016 U.S. News & World Report, on short-term (≤six months) and long-term (≥one year) weight loss outcomes in overweight and obese adults. For the present review, all diets in the 2016 U.S. News & World Report Rankings for "Best Weight-Loss Diets", which did not involve specific calorie targets, meal replacements, supplementation with commercial products, and/or were not categorized as "low-calorie" diets were examined...
July 31, 2017: Nutrients
Andrew M Freeman, Pamela B Morris, Neal Barnard, Caldwell B Esselstyn, Emilio Ros, Arthur Agatston, Stephen Devries, James O'Keefe, Michael Miller, Dean Ornish, Kim Williams, Penny Kris-Etherton
The potential cardiovascular benefits of several trending foods and dietary patterns are still incompletely understood, and nutritional science continues to evolve. However, in the meantime, a number of controversial dietary patterns, foods, and nutrients have received significant media exposure and are mired by hype. This review addresses some of the more popular foods and dietary patterns that are promoted for cardiovascular health to provide clinicians with accurate information for patient discussions in the clinical setting...
March 7, 2017: Journal of the American College of Cardiology
Dean Ornish
No abstract text is available yet for this article.
February 23, 2015: Time
Emily V Nosova, Michael S Conte, S Marlene Grenon
OBJECTIVE: Peripheral arterial disease (PAD) is a burdensome cardiovascular condition that results from chronic inflammatory insults to the arterial vasculature. Key risk factors include age, gender, type 2 diabetes mellitus, hypertension, hypercholesterolemia, hyperhomocysteinemia, smoking, lack of physical fitness, and poor diet, the latter three being modifiable in the development and progression of PAD. A growing body of evidence indicates that imbalanced nutrient intake may contribute to the development and progression of PAD...
January 2015: Journal of Vascular Surgery
Moaven Razavi, Stephen Fournier, Donald S Shepard, Grant Ritter, Gail K Strickler, William B Stason
Medicare conducted a payment demonstration to evaluate the effectiveness of two intensive lifestyle modification programs in patients with symptomatic coronary artery disease: the Dr. Dean Ornish Program for Reversing Heart Disease (Ornish) and Cardiac Wellness Program of the Benson-Henry Mind Body Institute. This report describes the changes in cardiac risk factors achieved by each program during the active intervention year and subsequent year of follow-up. The demonstration enrolled 580 participants who had had an acute myocardial infarction, had undergone coronary artery bypass graft surgery or percutaneous coronary intervention within 12 months, or had documented stable angina pectoris...
2014: PloS One
M Sagner, D Katz, G Egger, L Lianov, K-H Schulz, M Braman, B Behbod, E Phillips, W Dysinger, D Ornish
No abstract text is available yet for this article.
November 2014: International Journal of Clinical Practice
Stephen Devries, James E Dalen, David M Eisenberg, Victoria Maizes, Dean Ornish, Arti Prasad, Victor Sierpina, Andrew T Weil, Walter Willett
No abstract text is available yet for this article.
September 2014: American Journal of Medicine
Dean Ornish, Jue Lin, June M Chan, Elissa Epel, Colleen Kemp, Gerdi Weidner, Ruth Marlin, Steven J Frenda, Mark Jesus M Magbanua, Jennifer Daubenmier, Ivette Estay, Nancy K Hills, Nita Chainani-Wu, Peter R Carroll, Elizabeth H Blackburn
BACKGROUND: Telomere shortness in human beings is a prognostic marker of ageing, disease, and premature morbidity. We previously found an association between 3 months of comprehensive lifestyle changes and increased telomerase activity in human immune-system cells. We followed up participants to investigate long-term effects. METHODS: This follow-up study compared ten men and 25 external controls who had biopsy-proven low-risk prostate cancer and had chosen to undergo active surveillance...
October 2013: Lancet Oncology
Wu Zeng, William B Stason, Stephen Fournier, Moaven Razavi, Grant Ritter, Gail K Strickler, Sarita M Bhalotra, Donald S Shepard
BACKGROUND: This study reports outcomes of a Medicare-sponsored demonstration of two intensive lifestyle modification programs (LMPs) in patients with symptomatic coronary heart disease: the Cardiac Wellness Program of the Benson-Henry Mind Body Institute (MBMI) and the Dr Dean Ornish Program for Reversing Heart Disease® (Ornish). METHODS: This multisite demonstration, conducted between 2000 and 2008, enrolled Medicare beneficiaries who had had an acute myocardial infarction or a cardiac procedure within the preceding 12 months or had stable angina pectoris...
May 2013: American Heart Journal
Søren Ventegodt, Joav Merrick
No abstract text is available yet for this article.
2012: International Journal of Adolescent Medicine and Health
Dean Ornish
No abstract text is available yet for this article.
April 9, 2012: Archives of Internal Medicine
Dean Ornish
No abstract text is available yet for this article.
September 2011: Lancet Oncology
Nita Chainani-Wu, Gerdi Weidner, Daniel M Purnell, Steven Frenda, Terri Merritt-Worden, Claudia Pischke, Rebecca Campo, Colleen Kemp, Edward S Kersh, Dean Ornish
The present study evaluated the changes in emerging cardiac biomarkers, cognitive function, and social support measures after a comprehensive lifestyle intervention that included a low-fat, whole-foods, plant-based diet, exercise, stress management, and group support meetings. We conducted a prospective cohort study of 131 participants (59.2% women and 43.1% with diabetes mellitus), 56 with coronary heart disease (CHD) (37.5% women and 27.3% diabetes mellitus), and 75 at high risk with ≥3 CHD risk factors and/or diabetes mellitus (76% women and 54...
August 15, 2011: American Journal of Cardiology
Judd Allen, David R Anderson, Bill Baun, Steven N Blair, Larry S Chapman, Michael Eriksen, Jonathan Fielding, Gil Omenn, Dean Ornish, Kenneth R Pelletier
No abstract text is available yet for this article.
March 2011: American Journal of Health Promotion: AJHP
(no author information available yet)
No abstract text is available yet for this article.
December 2010: Harvard Heart Letter: From Harvard Medical School
Bonnie J Horrigan
No abstract text is available yet for this article.
November 2010: Explore: the Journal of Science and Healing
Huaidong Du, Edith Feskens
Obesity has become a serious public health problem worldwide, and dietary composition can play a role in its prevention and treatment. However, available literature on the impacts of different dietary factors on weight change is inconsistent, or even conflicting. In this review, we briefly summarized the mechanisms and influences of several major dietary determinants of weight change, with a focus on their potential in the prevention of weight gain or regain. We discussed the intake of fat, protein, total carbohydrates, fruits and vegetables, fibre, free sugars, fructose and sugar sweetened beverages, dietary energy density, portion size, eating outside home, glycaemic index and glycaemic load...
August 2010: Acta Cardiologica
Claudia R Pischke, Melanie Elliott-Eller, Minmin Li, Nancy Mendell, Dean Ornish, Gerdi Weidner
BACKGROUND AND RESEARCH OBJECTIVE: It is unclear whether lifestyle changes can delay the need for surgical procedures in coronary heart disease (CHD) patients with asymptomatic reduced left ventricular ejection fraction (LVEF). The aim of this pilot study was to examine whether lifestyle changes can delay the need for surgical procedures in this population. SUBJECTS AND METHODS: We compared 3-year clinical events in 27 CHD patients eligible to receive revascularization (by insurance standards), but underwent lifestyle changes (low-fat diet, exercise, stress management) instead (intervention group [IG], LVEF < or =40%), with those of a historically matched (age, gender, LVEF, and stenosis of the 3 major coronary arteries) control group receiving usual care (UCG; n = 13) who received revascularization at study entry...
September 2010: Journal of Cardiovascular Nursing
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