Torus

This paper presents a haptic actuator made of silicone rubber to provide both passive and active haptic forces for catheter simulations. The haptic actuator has a torus outer shape with an ellipse-shaped inside chamber which is actuated by hydraulic pressure. Expansion of the chamber by providing positive pressure can squeeze the inside passage to resist the catheter traveling through. Further expansion can hold and push back the catheter in the axial direction to render active haptic forces. The size of the catheter passage is increased by providing negative pressure to the chamber, allowing various diameters of the actual medical catheters to be used and exchanged during the simulation...

Adenosine A2A receptors (A2AAR) evoke pleiotropic intracellular signaling events via activation of the stimulatory heterotrimeric G protein, Gs. Here, we used cryoEM to solve the agonist-bound structure of A2AAR in a complex with full-length Gs alpha and Gbeta4gamma2. The orthosteric binding site of A2AAR-Gs alpha:beta4gamma2 was similar to other structures of agonist-bound A2AAR, with or without Gs. Unexpectedly, the solvent accessible surface area within the interior of the complex was substantially larger for the complex with Gbeta4 versus the closest analog, A2AAR-miniGs alpha:beta1gamma2...

Toric focal conic domains (TFCDs) in smectic liquid crystals exhibit distinct topological characteristics, featuring torus-shaped molecular alignment patterns with rotational symmetry around a central core. TFCDs have attracted much interest due to their unique topological structures and properties, enabling not only fundamental studies but also potential applications in liquid crystal (LC)-based devices. Here, we investigated the precise spatial control of the arrangement of TFCDs using micropatterns and sublimation of TFCDs to estimate the energy states of the torus-like structures...

We construct a unitary, modular-invariant torus partition function of a two-dimensional conformal field theory with a Virasoro primary spectral gap of Δ_{*}=[(c-1)/12] above the vacuum. The twist gap is identical, apart from two states O_{*} with spin scaling linearly in the central charge c. These states admit an AdS_{3} interpretation as strongly coupled strings. All other states are black hole microstates.

The torus semicircularis (TS) of teleosts is a key midbrain center of the lateral line and acoustic sensory systems. To characterize the TS in adult zebrafish, we studied their connections using the carbocyanine tracers applied to the TS and to other related nuclei and tracts. Two main TS nuclei, central and ventrolateral, were differentiable by their afferent connections. From central TS, (TSc) numerous toropetal cells were labeled bilaterally in several primary octaval nuclei (anterior, magnocellular, descending, and posterior octaval nuclei), in the secondary octaval nucleus, in the caudal octavolateralis nucleus, and in the perilemniscular region...

In this paper, we investigate bifurcations of equilibria and transients by using modified rate equations of semiconductor lasers (SCLs) subjected to optical injection. An analytical study is performed to demonstrate some two-parameter bifurcations, inter alia, Bogdanov-Takens and Gavrilov-Guckenheimer bifurcations. A detailed numerical study based on the multiparametric bifurcation method and using 3D-plots and projections reveal a rich locking dynamics of SCLs. In this way, a so-called zero frequency detuning well is highlighted in the vicinity of a Hopf bifurcation confining minimal states of the larger Lyapunov exponent in injection locking curves...

Liquid structures of thin-films and torus droplets are omnipresent in daily lives. The morphological evolution of liquid structures suspending in another immiscible fluid and sitting on a solid substrate is investigated by using three-dimensional (3D) phase-field (PF) simulations. Here, we address the evolution dynamics by scrutinizing the interplay of surface energy, kinetic energy, and viscous dissipation, which is characterized by Reynolds number Re and Weber number We. We observe special droplet breakup phenomena by varying Re and We...

The tail rotor of a helicopter, a crucial component, traditionally relies on a complex drive mode involving reducers and transmission gears. This conventional setup, with its lengthy transmission chain and numerous components, hinders miniaturization efforts. In response to this challenge, our paper presents a novel piezoelectric drive approach. Our objective was to suggest an innovative design capable of minimizing the components involved in the tail rotor drive. This design can be adjusted in size according to specific requirements and is effective up to a specified speed...

To achieve optimal operation of the polarimetry-based FOCS, the light polarisation state at the input of the sensing fibre part must be close to a linear one. In the case of a FOCS deployed on a tokamak, the Joint European Torus (JET) in the present work, the long fibre optics link between the laser source and the sensing fibre modifies the polarisation in an unpredictable way, making it unclear which source polarisation state is to be set. A method for performing the necessary polarisation adjustment in a systematic way is proposed based on the FOCS analysis...

PURPOSE: Direct Discharge protocols (DD) can alleviate strain on healthcare systems by reducing routine outpatient follow-up. These protocols include low-complex musculoskeletal injuries, such as isolated greenstick fractures or torus fractures of the wrist in children. While there is consensus on the effectiveness of DD, there is a lack of injury-specific powered studies. This study compares treatment satisfaction between DD and traditional treatment in children with a greenstick fracture or torus fractures of the wrist...

A versatile method for the automated synthesis of composites containing DNA-oligonucleotides and boron cluster scaffolds and their assembly into functional nanoparticles is described. The obtained, torus-like nanoparticles carry antisense oligonucleotides that target two different oncogenes simultaneously. The nanoparticles exhibited notable silencing efficiency in vitro in a pancreatic carcinoma cell line PANC-1 toward EGFR and c-Myc genes at the mRNA level, and a significant efficiency at the protein level...

A knot is a circle piecewise-linearly embedded into the 3-sphere. The topology of a knot is intimately related to that of its exterior, which is the complement of an open regular neighborhood of the knot. Knots are typically encoded by planar diagrams, whereas their exteriors, which are compact 3-manifolds with torus boundary, are encoded by triangulations. Here, we give the first practical algorithm for finding a diagram of a knot given a triangulation of its exterior. Our method applies to links as well as knots, and allows us to recover links with hundreds of crossings...

The self-assembly of organic amphiphilic species into various aggregates such as spherical or elongated micelles and cylinders up to the formation of lyotropic hexagonal or lamellar phases results from cooperative processes orchestrated by the hydrophobic effect, while those involving ionic inorganic polynuclear entities and nonionic organic components are still intriguing. Herein, we report on the supramolecular behavior of giant toroidal molybdenum blue-type polyoxometalate, namely, the {Mo154 } species in the presence of n-octyl-β-glucoside (C8G1), widely used as a surfactant in biochemistry...

BACKGROUND: Vascular structure, blood oxygen saturation, and melanin status of the epidermis are chromophore factors related to light absorption. Therefore, they are likely to be related to skin appearance. Thus, it is important to measure these internal skin features and understand their characteristics. Thus, we aimed to analyze the individual differences and aging changes in the skin by measuring the internal skin characteristics, such as vascular structure, oxygen saturation, and the 3D distribution of melanin in the epidermis, using a noninvasive photoacoustic (PA) measurement method...

Milk protein genetic polymorphisms are associated with economically important traits in dairy cattle. The objective of this study is to genotype a single nucleotide polymorphism (SNP) responsible for the amino acid changes in the beta-lactoglobulin (β-Lg) variants A and B on 85 unrelated DNA representing Algerian cattle populations: Chelifienne (28), Cheurfa (31) and Guelmoise (26). The method used is the PCR-RFLP (Polymerase Chain Reaction-Restriction Fragment Length Polymorphism). Genetic polymorphism was detected by digestion of PCR products amplified of exon II of β-Lg gene by with the endonuclease Hae III enzyme...

68 Ga-PSMA PET/CT has been routinely utilized in patients with intermediate to high-risk category prostate carcinoma for staging, biochemical recurrence and before planning the PSMA radioligand therapy (RLT). 177 Lu-PSMA RLT has also been approved by FDA as a novel treatment modality in metastatic carcinoma prostate patients who have failed to other lines of treatment. The non-target organs like salivary and lacrimal glands have shown to have high physiological PSMA uptake on PSMA PET/CT. Recently, strong uptake of PSMA ligand has also been noted in the dorsal wall of the nasopharynx in the region of torus tubarius on PSMA PET/CT, which has led to the identification of new pair of salivary gland structures called "tubarial salivary glands"...

OBJECTIVE: The aim of this study is to compare the clinical results of splint, short arm circular plaster, and soft bandage immobilization methods applied in the treatment of wrist torus fractures in a single center. METHODS: Patients treated for torus fractures at a tertiary trauma hospital between January 2018 and January 2022 were analyzed retrospectively. According to the physician's preference, a splint, short arm circular plaster, or soft bandage was applied to each patient...

This case report describes the case of a man in his seventies presenting with a nasopharyngeal deposit of myeloid sarcoma associated with acute monomyelocytic leukaemia. He presented with right nasal obstruction associated with unilateral pulsatile tinnitus. CT and MRI scans of sinuses identified a moderately restricting mucosal swelling of the right torus tubarius, and a biopsy of the lesion diagnosed a nasal deposit of myeloid sarcoma.

Krylov complexity is an important dynamical quantity with relevance to the study of operator growth and quantum chaos and has recently been much studied for various time-independent systems. We initiate the study of K complexity in time-dependent (driven) quantum systems. For periodic time-dependent (Floquet) systems, we develop a natural method for doing the Krylov construction and then define (state and operator) K complexity for such systems. Focusing on kicked systems, in particular the quantum kicked rotor on a torus, we provide a detailed numerical study of the time dependence of Arnoldi coefficients as well as of the K complexity with the system coupling constant interpolating between the weak and strong coupling regimes...

We study the Cauchy problem for the advection-diffusion equation <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msub><mml:mi>∂</mml:mi><mml:mi>t</mml:mi></mml:msub><mml:mi>u</mml:mi><mml:mo>+</mml:mo><mml:mrow><mml:mspace/><mml:mtext>div</mml:mtext><mml:mspace/></mml:mrow><mml:mrow><mml:mo>(</mml:mo><mml:mi>u</mml:mi><mml:mrow><mml:mi>b</mml:mi></mml:mrow><mml:mo>)</mml:mo></mml:mrow><mml:mo>=</mml:mo><mml:mi>Δ</mml:mi><mml:mi>u</mml:mi></mml:mrow></mml:math> associated with a merely integrable divergence-free vector field <mml:math xmlns:mml="https://www...