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High flow nasal cannula

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https://www.readbyqxmd.com/read/29910540/high-flow-nasal-cannula-versus-conventional-oxygen-therapy-in-children-with-respiratory-distress
#1
Punthila Sitthikarnkha, Rujipat Samransamruajkit, Nuanchan Prapphal, Jitladda Deerojanawong, Suchada Sritippayawan
Purpose: The aim of this study is to determine the clinical efficacy of high-flow nasal cannula (HFNC) therapy compared with conventional oxygen therapy in children presented with respiratory distress. Study Design: This was a randomized controlled study. Materials and Methods: Infants and children aged between 1 month to 5 years who were admitted to our tertiary referral center for respiratory distress (July 1, 2014 to March 31, 2015) and met the inclusion criteria were recruited...
May 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29890848/inhaled-epoprostenol-through-noninvasive-routes-of-ventilator-support-systems
#2
Mahmoud A Ammar, Madhu Sasidhar, Simon W Lam
BACKGROUND: The administration of inhaled epoprostenol (iEPO) through noninvasive routes of ventilator support systems has never been previously evaluated. OBJECTIVE: Describe the use of iEPO when administered through noninvasive routes of ventilator support systems. METHODS: Critically ill patients admitted to the intensive care unit who received iEPO through noninvasive routes were analyzed. Improvements in respiratory status and hemodynamic parameters were evaluated...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29880578/accuracy-of-administrative-codes-for-distinguishing-positive-pressure-ventilation-from-high-flow-nasal-cannula
#3
Ryan J Good, Matthew K Leroue, Angela S Czaja
OBJECTIVES: Noninvasive positive pressure ventilation (NIPPV) is increasingly used in critically ill pediatric patients, despite limited data on safety and efficacy. Administrative data may be a good resource for observational studies. Therefore, we sought to assess the performance of the International Classification of Diseases, Ninth Revision procedure code for NIPPV. METHODS: Patients admitted to the PICU requiring NIPPV or heated high-flow nasal cannula (HHFNC) over the 11-month study period were identified from the Virtual PICU System database...
June 7, 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29880331/clinical-outcomes-of-oxygen-therapy-using-high-flow-nasal-cannula-in-japan
#4
EDITORIAL
Makoto Hasegawa
No abstract text is available yet for this article.
June 4, 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29866165/first-line-support-for-assistance-in-breathing-in-children-first-abc-a-multicentre-pilot-randomised-controlled-trial-of-high-flow-nasal-cannula-therapy-versus-continuous-positive-airway-pressure-in-paediatric-critical-care
#5
Padmanabhan Ramnarayan, Paula Lister, Troy Dominguez, Parviz Habibi, Naomi Edmonds, Ruth R Canter, Jerome Wulff, David A Harrison, Paul M Mouncey, Mark J Peters
BACKGROUND: Although high-flow nasal cannula therapy (HFNC) has become a popular mode of non-invasive respiratory support (NRS) in critically ill children, there are no randomised controlled trials (RCTs) comparing it with continuous positive airway pressure (CPAP). We performed a pilot RCT to explore the feasibility, and inform the design and conduct, of a future large pragmatic RCT comparing HFNC and CPAP in paediatric critical care. METHODS: In this multi-centre pilot RCT, eligible patients were recruited to either Group A (step-up NRS) or Group B (step-down NRS)...
June 4, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29844209/incorporating-a-nebulizer-system-into-high-flow-nasal-cannula-improves-comfort-in-infants-with-bronchiolitis
#6
Juan Valencia-Ramos, Alicia Mirás, Amacia Cilla, Carlos Ochoa, Juan Arnaez
BACKGROUND: High-flow nasal cannula (HFNC) is increasingly used to provide respiratory support in infants with bronchiolitis. The delivery of aerosol therapy through a jet nebulizer is widely indicated despite its controversial efficacy and poor tolerability. METHODS: This randomized cross-over study aimed to evaluate the comfort and satisfaction of the delivery of aerosol therapy using a nebulization system integrated into HFNC compared with the standard practice of using a jet nebulizer with a face mask...
May 29, 2018: Respiratory Care
https://www.readbyqxmd.com/read/29802651/using-high-flow-nasal-cannulas-for-infants-with-bronchiolitis-admitted-to-paediatric-wards-is-safe-and-feasible
#7
Paula Heikkilä, Paula Sokuri, Minna Mecklin, Kirsi Nuolivirta, Terhi Tapiainen, Outi Peltoniemi, Marjo Renko, Matti Korppi
AIM: Using a high-flow nasal cannula (HFNC) for infant bronchiolitis is increasingly common, but insufficiently studied. In this retrospective study, we examined the outcomes of HFNC and compared infants who did and did not respond to this oxygen delivery method. METHODS: This 2012-2015 study of six Finnish hospitals focused on 88 infants under 12 months who received HFNC: 53 on paediatric wards and 35 in paediatric intensive care units (PICUs). We reviewed patient files for underlying factors, clinical parameters and HFNC treatment...
May 26, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29797429/factors-contributing-to-the-failure-of-humidified-high-flow-nasal-cannulae
#8
Sophia Teoh, Elizabeth Clyde, Theodore Dassios, Anne Greenough
The use of humidified high-flow nasal cannulae (HHFNC) as an alternative mode of non-invasive ventilation (NIV) in neonates has become widespread. A survey of UK neonatal units showed the proportion using HHFNC had increased from 56% in 2012 to 87% in 2015 (1). A recently reported Cochrane Review (2) comparing the use of HHFNC against other NIV modes of ventilation immediately after birth or following extubation showed no significant difference in the rates of bronchopulmonary dysplasia (BPD) or death and no significant difference in the rates of treatment failure/reintubation...
May 24, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29773297/the-clinical-practice-of-high-flow-nasal-cannula-oxygen-therapy-in-adults-a-japanese-cross-sectional-multicenter-survey
#9
Jiro Ito, Kazuma Nagata, Susumu Sato, Akira Shiraki, Naoki Nishimura, Shinyu Izumi, Ryo Tachikawa, Takeshi Morimoto, Keisuke Tomii
BACKGROUND: High-flow nasal cannula oxygen therapy (HFNC) is widely used mainly in the acute care setting, but limited data are available on real-world practice in adults. The objective of this study was to describe HFNC practices in Japanese adults. METHODS: A retrospective cross-sectional multicenter survey of adult patients receiving HFNC from January through March 2015 was conducted in 33 participating hospitals in Japan. RESULTS: We obtained information on 321 patients (median age, 76; 218 men, 103 women; median estimated PaO2 /FI O2, 178 mm Hg) from 22 hospitals...
May 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29751368/rapid-systematic-review-shows-that-using-a-high-flow-nasal-cannula-is-inferior-to-nasal-continuous-positive-airway-pressure-as-first-line-support-in-preterm-neonates
#10
REVIEW
Francesca Conte, Luigi Orfeo, Camilla Gizzi, Luca Massenzi, Salvatore Fasola
AIM: We reviewed using a high-flow nasal cannula (HFNC) as first-line support for preterm neonates with, or at risk of, respiratory distress. METHODS: This rapid systematic review covered biomedical databases up to June 2017. We included randomised controlled trials (RCTs) published in English. The reference lists of the studies and relevant reviews we included were also screened. We performed the study selection, data extraction, study quality assessment, meta-analysis and quality of evidence assessment following the Grading of Recommendations Assessment, Development and Evaluation system...
May 11, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29743098/impact-of-flow-and-temperature-on-patient-comfort-during-respiratory-support-by-high-flow-nasal-cannula
#11
Tommaso Mauri, Alessandro Galazzi, Filippo Binda, Laura Masciopinto, Nadia Corcione, Eleonora Carlesso, Marta Lazzeri, Elena Spinelli, Daniela Tubiolo, Carlo Alberto Volta, Ileana Adamini, Antonio Pesenti, Giacomo Grasselli
BACKGROUND: The high-flow nasal cannula (HFNC) delivers up to 60 l/min of humidified air/oxygen blend at a temperature close to that of the human body. In this study, we tested whether higher temperature and flow decrease patient comfort. In more severe patients, instead, we hypothesized that higher flow might be associated with improved comfort. METHODS: A prospective, randomized, cross-over study was performed on 40 acute hypoxemic respiratory failure (AHRF) patients (PaO2 /FiO2  ≤ 300 + pulmonary infiltrates + exclusion of cardiogenic edema) supported by HFNC...
May 9, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29733972/application-of-an-inline-dry-powder-inhaler-to-deliver-high-dose-pharmaceutical-aerosols-during-low-flow-nasal-cannula-therapy
#12
Dale Farkas, Michael Hindle, P Worth Longest
Inline dry powder inhalers (DPIs) offer a potentially effective option to deliver high dose inhaled medications simultaneously with mechanical ventilation. The objective of this study was to develop an inline DPI that is actuated using a low volume of air (LV-DPI) to efficiently deliver pharmaceutical aerosols during low flow nasal cannula (LFNC) therapy. A characteristic feature of the new inline LV-DPIs was the use of hollow capillary tubes that both pierced the capsule and provided a pathway for inlet air and exiting aerosol...
May 5, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29719796/use-of-high-flow-nasal-cannula-in-obese-patients-receiving-colonoscopy-under-intravenous-propofol-sedation-a-case-series
#13
Chi Chan Lee, Osman Perez, Faryal I Farooqi, Trupti Akella, Sameer Shaharyar, Melissa Elizee
Intravenous sedation during colonoscopy has become the standard practice in the United States given its higher patient satisfaction and procedural quality. This practice is not free of side effects as a significant proportion of patients undergoing this procedure tend to have respiratory depression and desaturation events. Obesity, as it relates to higher levels of body mass index (BMI) has a positive correlation with the incidence of hypoxemia. During colonoscopy High flow nasal cannula (HFNC) may potentially improve oxygen performance in patients receiving colonoscopy under intravenous sedation...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29713153/long-term-effects-of-oxygen-enriched-high-flow-nasal-cannula-treatment-in-copd-patients-with-chronic-hypoxemic-respiratory-failure
#14
Line Hust Storgaard, Hans-Ulrich Hockey, Birgitte Schantz Laursen, Ulla Møller Weinreich
Background: This study investigated the long-term effects of humidified high-flow nasal cannula (HFNC) in COPD patients with chronic hypoxemic respiratory failure treated with long-term oxygen therapy (LTOT). Patients and methods: A total of 200 patients were randomized into usual care ± HFNC. At inclusion, acute exacerbation of COPD (AECOPD) and hospital admissions 1 year before inclusion, modified Medical Research Council (mMRC) score, St George's Respiratory Questionnaire (SGRQ), forced expiratory volume in 1 second (FEV1 ), 6-minute walk test (6MWT) and arterial carbon dioxide (PaCO2 ) were recorded...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29696135/successful-deployment-of-high-flow-nasal-cannula-in-a-peruvian-pediatric-intensive-care-unit-using-implementation-science-lessons-learned
#15
Katie R Nielsen, Rosario Becerra, Gabriela Mallma, José Tantaleán da Fieno
Acute lower respiratory infections are the leading cause of death outside the neonatal period for children less than 5 years of age. Widespread availability of invasive and non-invasive mechanical ventilation in resource-rich settings has reduced mortality rates; however, these technologies are not always available in many low- and middle-income countries due to the high cost and trained personnel required to implement and sustain their use. High flow nasal cannula (HFNC) is a form of non-invasive respiratory support with growing evidence for use in pediatric respiratory failure...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29685370/is-high-flow-nasal-cannula-more-effective-than-conventional-oxygen-therapy-for-preventing-escalation-of-respiratory-support-in-patients-with-acute-respiratory-failure
#16
EDITORIAL
Brit Long, Michael D April
No abstract text is available yet for this article.
April 20, 2018: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29681814/non-gestational-choriocarcinoma-with-widespread-metastases-presenting-with-type-1-respiratory-failure-in-a-39-year-old-female-case-report-and-review-of-the-literature
#17
Louisa Stockton, Elizabeth Green, Baljeet Kaur, Emma De Winton
Introduction: Non-gestational choriocarcinoma (NGCC) is an extremely rare cancer. We report a case presenting in extremis. Case Report: A 39-year-old woman presented with type 1 respiratory failure with a 1-month history of breathlessness. Computed tomography (CT) revealed widespread metastatic disease involving the lungs, liver, pancreas, and breast. Serum β-human chorionic gonadotropin was markedly raised. Over 72 h, she deteriorated and was started on high-flow nasal cannula to facilitate discussions and for comfort...
January 2018: Case Reports in Oncology
https://www.readbyqxmd.com/read/29674770/incidence-of-pulmonary-complications-with-the-prophylactic-use-of-high-flow-nasal-cannula-after-pediatric-cardiac-surgery-prophylactic-hfnc-study-protocol
#18
Naohiro Shioji, Tomoyuki Kanazawa, Tatsuo Iwasaki, Kazuyoshi Shimizu, Tomohiko Suemori, Hirokazu Kawase, Satoshi Kimura, Yasutoshi Kuroe, Hiroshi Morimatsu
We will investigate the incidence of postoperative pulmonary complications (PPCs) with the prophylactic use of a high-flow nasal cannula (HFNC) after pediatric cardiac surgery. Children < 48 months old with congenital heart disease for whom cardiac surgery is planned will be included. The HFNC procedure will be commenced just after extubation, at a flow rate of 2 L/kg/min with adequate oxygen concentration to achieve target oxygen saturation ≥ 94%. This study will reveal the prevalence of PPCs after pediatric cardiac surgery with the prophylactic use of HFNC...
April 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29643554/effectiveness-of-transnasal-humidified-rapid-insufflation-ventilatory-exchange-versus-traditional-preoxygenation-followed-by-apnoeic-oxygenation-in-delaying-desaturation-during-apnoea-a-preliminary-study
#19
Sunil Rajan, Nandhini Joseph, Pulak Tosh, Dilesh Kadapamannil, Jerry Paul, Lakshmi Kumar
Background and Aims: Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) during apnoea has shown to delay desaturation. The primary objective was to compare time to desaturate to <90% during apnoea with THRIVE versus traditional preoxygenation followed by apnoeic oxygenation. Methods: This prospective, randomised, single-blinded study was conducted in 10 adult patients presenting for direct laryngoscopy under general anaesthesia without endotracheal intubation...
March 2018: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/29621755/reply-to-the-letter-to-the-editor-is-high-flow-nasal-cannula-useful-as-primary-respiratory-support-in-preterm-infants
#20
Srinivas Murki, Nandkishor S Kabra
No abstract text is available yet for this article.
April 5, 2018: Neonatology
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