Sara Nutley, Binh K Nguyen, Robert Scott Mackin, Philip S Insel, Duygu Tosun, Meryl Butters, Paul Aisen, Rema Raman, Andrew J Saykin, Arthur W Toga, Clifford Jack, Michael W Weiner, Craig Nelson, Michelle Kassel, Maria Kryza-Lacombe, Joseph Eichenbaum, Rachel L Nosheny, Carol A Mathews
Hoarding disorder (HD) is a debilitating neuropsychiatric condition that affects 2%-6% of the population and increases in incidence with age. Major depressive disorder (MDD) co-occurs with HD in approximately 50% of cases and leads to increased functional impairment and disability. However, only one study to date has examined the rate and trajectory of hoarding symptoms in older individuals with a lifetime history of MDD, including those with current active depression (late-life depression; LLD). We therefore sought to characterize this potentially distinct phenotype...
November 23, 2023: American Journal of Geriatric Psychiatry