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Wounded healer

Muluken Wubetu, Tefera Abula, Getye Dejenu
BACKGROUND: One of the services that plants provide for human beings is their wider medicinal application. Although it is not fully assessed, the practice and wider use of traditional medicine is frequent in Ethiopia. Studies conducted previously are confined to the perceptions of modern and traditional health practitioners about traditional medicine. A total of 45 informants were selected purposefully from the study area. For collecting the data, semi-structured interviewees, observation and field walks were employed from August 10 to September 30/2014...
April 18, 2017: BMC Research Notes
Mohd Azri Abd Jalil, Abdul Razak Kasmuri, Hazrina Hadi
BACKGROUND: The stingless bee is a natural type of bee that exists in almost every continent. The honey produced by this bee has been widely used across time and space. The distinctive feature of this honey is that it is stored naturally in the pot (cerumen), thus contributing to its beneficial properties, especially in the wound healing process. METHODS: In this article, several studies on stingless bee honey that pointed out the numerous therapeutic profiles of this honey in terms of its antioxidant, antimicrobial, anti-inflammatory, as well as moisturizing properties are reviewed...
March 15, 2017: Skin Pharmacology and Physiology
Karl Egil Malterud
The ethnopharmacology, chemistry and pharmacology of four Malian medicinal plants, Biophytum umbraculum, Burkea africana, Lannea velutina and Terminalia macroptera are reviewed. These plants are used by traditional healers against numerous ailments: malaria, gastrointestinal diseases, wounds, sexually transmitted diseases, insect bites and snake bites, etc. The scientific evidence for these uses is, however, limited. From the chemical and pharmacological evidence presented here, it seems possible that the use in traditional medicine of these plants may have a rational basis, although more clinical studies are needed...
February 21, 2017: Plants (Basel, Switzerland)
Sudharsana Sundarrajan, Mohanapriya Arumugam
Psoriasis is a chronic relapsing immune mediated disorder of the skin. The disease presents itself with well featured clinical and histological characteristics however the aetiology of the disease still remains obscure. The current systemic therapies aim to eliminate the symptoms of disease rather than offering a complete cure. Parangichakkai chooranam (PC), a Siddha oral herbal formulation has been widely prescribed for the treatment of psoriasis. Though the medication is highly prescribed by the Siddha healers the mechanism of PC for the treatment of psoriasis remains to be elucidated...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
E Düsman, I V Almeida, L T D Tonin, V E P Vicentini
Barbados cherry (BC) (Malpighia glabra Linnaeus) is a functional fruit that is consumed to prevent disease. It is used as an adjuvant in the treatment of several diseases, and acts as an antianemic, an appetite stimulant, a wound healer, an anti-inflammatory, a mineralizer, an antifungal, and an antioxidant agent. Several chemotherapeutic agents, such as cyclophosphamide, may result in undesirable side effects, and generate mutations in normal cells. Thus, the present study evaluated the antimutagenic potential of the fresh (BCN) and frozen (BCF) juices of BC pulp, with and without concomitant administration of cyclophosphamide, using a chromosomal aberration test system in the bone marrow cells of Wistar rats treated in vivo for 24 h...
December 19, 2016: Genetics and Molecular Research: GMR
Nikki Traylor-Knowles
Wound healing is a critical physiological function needed for survival in all marine organisms. However, it is particularly critical in organisms like corals, which cannot escape predators. In this study, I characterized the gross morphology of wound healing in Pocillopora damicornis and Acropora hyacinthus found in two pools with distinct previously documented temperature profiles in Ofu, American Samoa. I observed differences between healing rates of A. hyacinthus versus P. damicornis, but no significant difference in healing rates between A...
2016: Marine Biology
Leyla Asena, Esra Hülya Suveren, Gülten Karabay, Dilek Dursun Altinors
PURPOSE: To investigate the effects of human breast milk on corneal epithelial wound healing. METHODS: The effects of human breast milk on epithelial healing is compared with autologous serum and artificial tears on 24 female Bal-b/C mice. A central corneal epithelial defect was created using a 2 mm trephine. Four groups were formed. By a random pick-up, topical human breast milk 4 × 1 was given to Group 1, topical mouse autologous serum 4 × 1 was applied to Group 2, and preservative-free artificial tears 4 × 1 was applied to Group 3...
October 19, 2016: Current Eye Research
Pradeep Bhaskar Bhat, Shruti Hegde, Vinayak Upadhya, Ganesh R Hegde, Prasanna V Habbu, Gangadhar S Mulgund
ETHNOPHARMACOLOGICAL RELEVANCE: Caesalpinia mimosoides Lam. is one of the important traditional folk medicinal plants in the treatment of skin diseases and wounds used by healers of Uttara Kannada district of Karnataka state (India). However scientific validation of documented traditional knowledge related to medicinal plants is an important path in current scenario to fulfill the increasing demand of herbal medicine. AIM OF THE STUDY: The study was carried out to evaluate the claimed uses of Caesalpinia mimosoides using antimicrobial, wound healing and antioxidant activities followed by detection of possible active bio-constituents...
December 4, 2016: Journal of Ethnopharmacology
Oratai Neamsuvan, Pattaraporn Bunmee
ETHNOPHARMACOLOGICAL RELEVANCE: Skin diseases are common health problems which affecting to all ages. In Thailand, the number of patients diagnosed with skin diseases is increasing every year. Nowadays, The Ministry of Public Health is supporting and promoting herbs for treating various disorders, including disorders of the skin to reduce the problem of antibiotic resistance and adverse drug reactions. This study aimed to: (1) enumerate the herbal weeds for treating skin disorders; (2) study local knowledge of weed utilization for treating skin disorders according to the folk healers in Songkhla and Krabi province; and (3) study quantitative data by Informant consensus factor (ICF), Use value (UV) and Fidelity level (FL) value...
December 4, 2016: Journal of Ethnopharmacology
Maurilio Giuseppe Maria Tavormina, Giuseppe Tavormina, Eugenio Nemoianni, Francesco Franza, Immacolata d'Errico, Maria Grazia Spurio, Romina Tavormina, Nicolas Zdanowicz, Stephanie De Mesmaeker, Judit Harangozó, Anna Nyulászi, Tünde Bulyáki, Ivan Urlic, Andrea Russo, Mark Agius
Prejudice and stigma about mental illness is still present in society. Patients suffer both from the disease, and from the marginalization behavior exhibited by others towards them and their families. Psychiatric professionals may also become ill and suffer for the same reason. The authors of this international multicenter study have set themselves the question of whether there may be prejudice and/or stigma among psychiatric professionals towards their suffering colleagues, among patients towards nursing staff affected by the same disease and between patients themselves...
September 2016: Psychiatria Danubina
Thuy Lan Nguyen, Anders Rusten, Mona Skogsrud Bugge, Karl Egil Malterud, Drissa Diallo, Berit Smestad Paulsen, Helle Wangensteen
ETHNOPHARMACOLOGICAL RELEVANCE: Syzygium guineense has been traditionally used in Mali in West Africa for the treatment of different diseases such as stomach problems, wounds, inflammations and various female disorders. AIMS OF THE STUDY: (1) To perform an ethnopharmacological survey on the traditional use of S. guineense among Malian healers. (2) To isolate and identify chemical constituents from S. guineense leaves and to study their radical scavenging and enzyme inhibitory effects...
November 4, 2016: Journal of Ethnopharmacology
Eric Koka, Dorothy Yeboah-Manu, Daniel Okyere, Philip Baba Adongo, Collins K Ahorlu
BACKGROUND: This study was conducted with the aim to understand some of the cultural belief systems in the management of wounds and patients practices that could contaminate wounds at the Obom sub-district of the Ga South Municipality of Ghana. METHODS: This was an ethnographic study using in-depth interviews, Focus Group Discussions and participant observation techniques for data collection. Observations were done on Buruli ulcer patients to document how they integrate local and modern wound management practices in the day-to-day handling of their wounds...
July 2016: PLoS Neglected Tropical Diseases
Jon K Amundson, Marc W Ross
While concern for the "wounds" of the patient are paramount in clinical practice, there is both historical and contemporary literature on wounding in the professional. In what follows, these perspectives are presented. Issues related to transference/counter-transference, the "wounded healer," vicarious traumatization, nocebo potential in informed consent, and the use of treatment as crucible for one's own development as clinician are discussed.
July 2016: American Journal of Clinical Hypnosis
Veera Venkata Satyanarayana Reddy Karri, Gowthamarajan Kuppusamy, Siddhartha Venkata Talluri, Sai Sandeep Mannemala, Radhakrishna Kollipara, Ashish Devidas Wadhwani, Shashank Mulukutla, Kalidhindi Rama Satyanarayana Raju, Rajkumar Malayandi
Diabetic wounds are a common complication in patients with diabetes that often lead to amputation. Although the pathophysiology of diabetic wound is multifactorial, chronic inflammation and lack of tissue regeneration leads to impair wound healing in diabetes. Application of curcumin (CUR) which is a well-known anti-inflammatory and antioxidant agent could be better strategy in diabetic wound healing. However, low bioavailability and poor stability of CUR hinders its application. Hence, in present study a novel nanohybrid scaffold has been prepared by incorporating CUR in chitosan nanoparticles (CSNPs) to improve stability and solubility followed by impregnation of prepared CUR-CSNPs into collagen scaffold (nanohybrid scaffold) for better tissue regeneration application...
December 2016: International Journal of Biological Macromolecules
Madiha Ahmed, Abdul Rehman Phul, Ihsan-ul Haq, Gulnaz Bibi, Kehkashan Mazhar, Tofeequr Rehman, Muhammad Zia, Bushra Mirza
Bergenia ciliata (locally known as Zakhm-e-hayat; wound healer) is commonly employed for wound healing, curing diarrhea and vomiting, fever, cough and pulmonary affections. Local community uses this plant as tea decoction with table salt. B. ciliata crude extract and its fractions were subjected to antibacterial, antioxidant effects as well as determination of total flavonoids and phenolics, DNA damage and anticancerous activities following standard protocols. Increased percentage inhibition of free radical in DPPH assay as well as elevated phenolic and flavonoid contents revealed antioxidant potential of this potent herb...
May 2016: Pakistan Journal of Pharmaceutical Sciences
Alexander Kwiatkowski, Mark Piatkowski, Miao Chen, Lijuan Kan, Qingshu Meng, Huimin Fan, Abdel-Hamid K Osman, Zhongmin Liu, Benjamin Ledford, Jia-Qiang He
Previous studies indicated that the fast-healer strain of MRL/MpJ-Fas(lpr)/J (MRL) mice demonstrated superior regenerative capabilities for digit wound healing and/or regeneration compared with the non-healer strain of C57BL/6 (C57) mice. These reports, however, mainly focused on morphological observations and analysis of gene expression with little attention on the role of angiogenesis in the amputated digits. By taking advantage of Laser Doppler Imaging and histological analysis, we examined the potential role(s) of angiogenesis in facilitating tissue regrowth/regeneration by comparing two strains of mice (MRL versus C57)...
May 13, 2016: Biochemical and Biophysical Research Communications
Rea Tschopp, Shiferaw Bekele, Abraham Aseffa
BACKGROUND: Rabies is a viral zoonosis that has been described in limited numbers of studies in Ethiopia at large and among pastoralists in particular. This study assessed dog demography, bite wound prevalence and management, potential risk factors of disease transmission and knowledge attitude practice towards rabies among urban dwellers, pastoralists and health workers in Awash, Eastern Ethiopia. METHODOLOGY: Information was collected by means of structured questionnaires and interviews and through medical and official records from the Agricultural and Health bureaus...
February 2016: PLoS Neglected Tropical Diseases
Nitin A Krishna, Hannah M Pennington, Canaan D Coppola, Marisa C Eisenberg, Richard C Schugart
The process of wound healing is governed by complex interactions between proteins and the extracellular matrix, involving a range of signaling pathways. This study aimed to formulate, quantify, and analyze a mathematical model describing interactions among matrix metalloproteinases (MMP-1), their inhibitors (TIMP-1), and extracellular matrix in the healing of a diabetic foot ulcer. De-identified patient data for modeling were taken from Muller et al. (Diabet Med 25(4):419-426, 2008), a research outcome that collected average physiological data for two patient subgroups: "good healers" and "poor healers," where classification was based on rate of ulcer healing...
December 2015: Bulletin of Mathematical Biology
Helle Wangensteen, Drissa Diallo, Berit Smestad Paulsen
ETHNOPHARMACOLOGICAL RELEVANCE: Mali is one of the countries in West Africa where the health system rely the most on traditional medicine. The healers are mainly using medicinal plants for their treatments. The studies performed being the basis for this review is of importance as they will contribute to sustaining the traditional knowledge. They contribute to evaluate and improve locally produced herbal remedies, and the review gives also an overview of the plant preparations that will have the most potential to be evaluated for new Improved Traditional Medicines...
December 24, 2015: Journal of Ethnopharmacology
Behlül Güler, Gülfidan Kümüştekin, Emin Uğurlu
ETHNOBOTANICAL RELEVANCE: The aim of this study is to document and describe important ethnobotanical features of 14 villages of Turgutlu (Manisa - Turkey). MATERIALS AND METHODS: The regular ethnobotanical surveys were carried out during different seasons in the years 2009 and 2010 in 14 villages of Turgutlu. The data was collected from 91 village inhabitants using semi-structured interviews. Use value (UV) was used to calculate the relative importance of species known by the inhabitants...
December 24, 2015: Journal of Ethnopharmacology
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