keyword
MENU ▼
Read by QxMD icon Read
search

Neomycin

keyword
https://www.readbyqxmd.com/read/28078622/evidence-that-polycystins-are-involved-in-hydra-cnidocyte-discharge
#1
Susan McLaughlin
Like other cnidarians, the freshwater organism Hydra is characterized by the possession of cnidocytes (stinging cells). Most cnidocytes are located on hydra tentacles, where they are organized along with sensory cells and ganglion cells into battery complexes. The function of the battery complexes is to integrate multiple types of stimuli for the regulation of cnidocyte discharge. The molecular mechanisms controlling the discharge of cnidocytes are not yet fully understood, but it is known that discharge depends on extracellular Ca(2+) and that mechanically induced cnidocyte discharge can be enhanced by the presence of prey extracts and other chemicals...
March 2017: Invertebrate Neuroscience: IN
https://www.readbyqxmd.com/read/28064050/development-of-a-novel-ph-sensitive-silane-crosslinked-injectable-hydrogel-for-controlled-release-of-neomycin-sulfate
#2
Sehrish Jabeen, Atif Islam, Abdul Ghaffar, Nafisa Gull, Ayesha Hameed, Anbreen Bashir, Tahir Jamil, Tousif Hussain
Silane crosslinked biopolymer based novel pH-responsive hydrogels were fabricated by blending the cationic (chitosan) and anionic (alginate) polymers with poly(vinyl alcohol). Tetraethoxysilane (TEOS) was used, as a crosslinker in different amounts due to its nonhazardous nature, to study its impact on physical and chemical properties of the prepared injectable hydrogels along with the controlled release of drug. The swelling response of the prepared hydrogels was examined in different solvent media which exhibited decreased swelling ratio with increase in the amount of TEOS...
January 4, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28053662/development-of-a-genome-editing-crispr-cas9-system-in-thermophilic-fungal-myceliophthora-species-and-its-application-to-hyper-cellulase-production-strain-engineering
#3
Qian Liu, Ranran Gao, Jingen Li, Liangcai Lin, Junqi Zhao, Wenliang Sun, Chaoguang Tian
BACKGROUND: Over the past 3 years, the CRISPR/Cas9 system has revolutionized the field of genome engineering. However, its application has not yet been validated in thermophilic fungi. Myceliophthora thermophila, an important thermophilic biomass-degrading fungus, has attracted industrial interest for the production of efficient thermostable enzymes. Genetic manipulation of Myceliophthora is crucial for metabolic engineering and to unravel the mechanism of lignocellulose deconstruction...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28012984/virulence-factors-and-antimicrobial-susceptibility-profile-of-extraintestinal-escherichia-coli-isolated-from-an-avian-colisepticemia-outbreak
#4
Jonas Fernandes Maciel, Letícia Beatriz Matter, Michele Martins Trindade, Giovana Camillo, Maristela Lovato, Sônia de Ávila Botton, Agueda Castagna de Vargas
In this study an avian colisepticemia outbreak was investigated. Two isolates from a chicken with colisepticemia were characterized for antimicrobial susceptibility and virulence factors profile. For this purpose 7 antimicrobial and 29 genes (fimH, hrlA/hek, iha, papC, sfa/focCD, tsh, mat, tia, gimB, ibeA, chuA, fyuA, ireA, iroN, irp2, iucD, sitD. chr., sitD. ep., iss, neuC, ompA, traT, astA, hlyA, sat, vat, pic, malX, cvi/cva) were tested. The outbreak happened in a hick chicken breeding located in the northwestern region of Rio Grande do Sul state in South of Brazil and caused 28...
December 21, 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28012630/antimicrobial-resistance-patterns-of-bovine-salmonella-enterica-isolates-submitted-to-the-wisconsin-veterinary-diagnostic-laboratory-2006-2015
#5
J R Valenzuela, A K Sethi, N A Aulik, K P Poulsen
Salmonellosis on the dairy continues to have a significant effect on animal health and productivity and in the United States. Additionally, Salmonella enterica subspecies enterica causes an estimated 1.2 million cases of human illness annually. Contributing to the morbidity and mortality in both human and domestic animal species is emergence of antimicrobial resistance by Salmonella species and increased incidence of multidrug-resistant isolates. This study describes serotype distribution and the antimicrobial resistance patterns for various Salmonella serotypes isolated from bovine samples submitted to the Wisconsin Veterinary Diagnostic Laboratory (WVDL) over the past 10 yr...
December 21, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/28005227/in-planta-production-and-characterization-of-a-hyperthermostable-gh10-xylanase-in-transgenic-sugarcane
#6
Jae Yoon Kim, Guang Nong, John D Rice, Maria Gallo, James F Preston, Fredy Altpeter
Sugarcane (Saccharum sp. hybrids) is one of the most efficient and sustainable feedstocks for commercial production of fuel ethanol. Recent efforts focus on the integration of first and second generation bioethanol conversion technologies for sugarcane to increase biofuel yields. This integrated process will utilize both the cell wall bound sugars of the abundant lignocellulosic sugarcane residues in addition to the sucrose from stem internodes. Enzymatic hydrolysis of lignocellulosic biomass into its component sugars requires significant amounts of cell wall degrading enzymes...
December 22, 2016: Plant Molecular Biology
https://www.readbyqxmd.com/read/27984024/prospective-randomized-clinical-trial-of-povidone-iodine-1-25-solution-versus-topical-antibiotics-for-treatment-of-bacterial-keratitis
#7
Sherwin J Isenberg, Leonard Apt, Mario Valenton, Savitri Sharma, Prashant Garg, Philip A Thomas, Pragya Parmar, Jayaraman Kaliamurthy, Johann M Reyes, Daniel Ong, Peter D Christenson, Madeline Del Signore, Gary N Holland
PURPOSE: To compare povidone-iodine 1.25% ophthalmic solution to topical antibiotics for treatment of bacterial keratitis in areas of the world where use of effective topical antibiotics may not be an option. STUDY DESIGN: Randomized, controlled, investigator-masked clinical trial. METHODS: We randomized 172 individuals with bacterial keratitis to topical treatment with povidone-iodine or antibiotics (neomycin-polymyxin B-gramicidin in the Philippines; ciprofloxacin 0...
October 27, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27976593/antimicrobial-resistance-in-enterococcus-strains-isolated-from-healthy-domestic-dogs
#8
Fabrizio Bertelloni, Claudia Salvadori, Giulia Lotti, Domenico Cerri, Valentina Virginia Ebani
Enterococci are opportunistic bacteria that cause severe infections in animals and humans, capable to acquire, express, and transfer antimicrobial resistance. Susceptibility to 21 antimicrobial agents was tested by the disk diffusion method in 222 Enterococcus spp. strains isolated from the fecal samples of 287 healthy domestic dogs. Vancomycin and ampicillin minimum inhibitory concentrations (MICs) and high-level aminoglycoside resistance (HLAR) tests were also performed. Isolates showed resistance mainly to streptomycin (88...
December 15, 2016: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/27956787/occurrence-and-antimicrobial-resistance-of-pathogenic-escherichia-coli-and-salmonella-spp-in-retail-raw-table-eggs-sold-for-human-consumption-in-enugu-state-nigeria
#9
O Josephine Okorie-Kanu, E Vivienne Ezenduka, C Onwuchokwe Okorie-Kanu, L Chinweokwu Ugwu, U John Nnamani
AIM: This study was conducted to investigate the occurrence of pathogenic Escherichia coli and Salmonella species in retail raw table eggs sold for human consumption in Enugu State and to determine the resistance of these pathogens to antimicrobials commonly used in human and veterinary practices in Nigeria. MATERIALS AND METHODS: A total of 340 raw table eggs comprising 68 composite samples (5 eggs per composite sample) were collected from five selected farms (13 composite samples from the farms) and 10 retail outlets (55 composite samples from the retail outlets) in the study area over a period of 4-month (March-June, 2014)...
November 2016: Veterinary World
https://www.readbyqxmd.com/read/27942459/genome-sequencing-and-annotation-of-aeromonas-veronii-strain-ae52-a-multidrug-resistant-isolate-from-septicaemic-gold-fish-carassius-auratus-in-sri-lanka
#10
S S S De S Jagoda, Karim Honein, Appudurai Arulkanthan, Hideki Ushio, Shuichi Asakawa
Here we report the draft genome sequence and annotation of A. veronii strain Ae52 isolated from the kidney of a morbund, septicaemic gold fish (Carassius auratus) in Sri Lanka. This clinical isolate showed resistance to multiple antimicrobials; amoxicillin, neomycin, trimethoprim-sulphonamide, chloramphenicol, tetracycline, enrofloxacin, erythromycin and nitrofurantoin. The size of the draft genome is 4.56 Mbp with 58.66% of G + C content consisting 4328 coding sequences. It harbors a repertoire of putative antibiotic resistant determinants that explains the genetic basis of its resistance to various classes of antibiotics...
March 2017: Genomics Data
https://www.readbyqxmd.com/read/27935615/aminoglycoside-based-novel-probes-for-bacterial-diagnostic-and-therapeutic-applications
#11
Qingyang Zhang, Qinghua Wang, Shengnan Xu, Limin Zuo, Xuefu You, Hai-Yu Hu
Specific detection of pathogens has long been recognized as a vital strategy in the control of infectious diseases. Two novel theranostic neomycin analogs exhibit efficient targeting, labelling and killing of broad spectrum bacteria while not damaging macrophage-like cells. Furthermore, lipidated probe 2 clearly showed antibacterial activity against methicillin-resistant S. aureus.
December 9, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27930817/assessment-of-virulence-factors-antibiotic-resistance-and-amino-decarboxylase-activity-in-enterococcus-faecium-mxvk29-isolated-from-mexican-chorizo
#12
Yenizey M Alvarez-Cisneros, Francisco J Fernández, Teresita Del Rosario Sáinz Espuñes, Edith Ponce-Alquicira
Enterococcus faecium MXVK29 has the ability to produce an antimicrobial compound that belongs to Class IIa of the Klaenhammer classification, and could be used as part of a biopreservation technology through direct inoculation of the strain as a starter or protective culture. However, Enterococcus is considered an opportunistic pathogen, so the purpose of this work was to study the food safety determinants of Enterococcus faecium MXVK29. The strain was sensitive to all of the antibiotics tested (penicillin, tetracycline, vancomycin, erythromycin, chloramphenicol, gentamicin, neomycin, kanamycin and netilmicin) and did not demonstrate histamine, cadaverine, or putrescine formation...
December 8, 2016: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/27930746/perinatal-natural-history-of-the-ts1cje-mouse-model-of-down-syndrome-growth-restriction-early-mortality-heart-defects-and-delayed-development
#13
Millie A Ferrés, Diana W Bianchi, Ashley E Siegel, Roderick T Bronson, Gordon S Huggins, Faycal Guedj
BACKGROUND: The Ts1Cje model of Down syndrome is of particular interest for perinatal studies because affected males are fertile. This permits affected pups to be carried in wild-type females, which is similar to human pregnancies. Here we describe the early natural history and growth profiles of Ts1Cje embryos and neonates and determine if heart defects are present in this strain. METHODS: Pups were studied either on embryonic (E) day 15.5, or from postnatal (P) day 3 through weaning on P21...
2016: PloS One
https://www.readbyqxmd.com/read/27913616/genetic-contributors-to-intergenerational-cag-repeat-instability-in-huntington-s-disease-knock-in-mice
#14
João Luís Neto, Jong-Min Lee, Ali Afridi, Tammy Gillis, Jolene R Guide, Stephani Dempsey, Brenda Lager, Isabel Alonso, Vanessa C Wheeler, Ricardo Mouro Pinto
Huntington's disease is a neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in exon 1 of the HTT gene. Longer repeat sizes are associated with increased disease penetrance and earlier ages of onset. Intergenerationally unstable transmissions are common in Huntington's disease families, partly underlying the genetic anticipation seen in this disorder. Huntington's disease CAG knock-in mouse models also exhibit a propensity for intergenerational repeat size changes. In this work, we examine intergenerational instability of the CAG repeat in over 20,000 transmissions in the largest Huntington's disease knock-in mouse model breeding datasets reported to date...
December 2, 2016: Genetics
https://www.readbyqxmd.com/read/27896620/antimicrobial-activity-of-topical-agents-against-propionibacterium-acnes-an-in-vitro-study-of-clinical-isolates-from-a-hospital-in-shanghai-china
#15
Ying Ma, Nanxue Zhang, Shi Wu, Haihui Huang, Yanpei Cao
This study aimed to compare the antimicrobial activities of topical agents against Propionibacterium acnes isolated from patients admitted to a hospital in Shanghai, China. The minimal inhibitory concentrations of the cultured P. acnes were determined in accordance with the Clinical and Laboratory Standards Institute. Susceptibilities to clindamycin and erythromycin were compared in terms of gender, age, disease duration, previous treatment, and disease severity. A total of 69 P. acnes strains were isolated from 98 patients (70...
November 28, 2016: Frontiers of Medicine
https://www.readbyqxmd.com/read/27884695/linker-dependent-intercalation-of-bisbenzimidazole-aminosugars-in-an-rna-duplex-selectivity-in-rna-vs-dna-binding
#16
Nihar Ranjan, Dev P Arya
Neomycin and Hoechst 33258 are two well-known nucleic acid binders that interact with RNA and DNA duplexes with high affinities respectively. In this manuscript, we report that covalent attachment of bisbenzimidazole unit derived from Hoechst 33258 to neomycin leads to intercalative binding of the bisbenzimidazole unit (oriented at 64-74° with respected to the RNA helical axis) in a linker length dependent manner. The dual binding and intercalation of conjugates were supported by thermal denaturation, CD, LD and UV-Vis absorption experiments...
December 15, 2016: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/27878810/improvement-of-phytoplankton-culture-isolation-using-single-cell-sorting-by-flow-cytometry
#17
Dominique Marie, Florence Le Gall, Roseline Edern, Priscillia Gourvil, Daniel Vaulot
Flow cytometry provides a tool to physically sort single algal cells in order to obtain clonal cultures. During sorting, cells are submitted to physical stress factors such as high fluidic pressure, exposure to the laser beam, electrostatic charges, deflection through high voltage fields and collisions with container surfaces. All of these can damage the cells of interest and success rates for initiation of cultures from flow-sorted cells are generally very low. We found that the addition of Bovine Serum Albumin (BSA) in the culture medium into which cells are sorted drastically improved the success of initiation of pico- and nano-eukaryotic phytoplankton strains...
November 22, 2016: Journal of Phycology
https://www.readbyqxmd.com/read/27872722/production-of-monoclonal-antibody-against-recombinant-ns3-protein-of-bovine-viral-diarrhea-virus-nadl-strain
#18
Masood Reza Seyfi Abad Shapouri, Maryam Ekhtelat, Masood Ghorbanpoor Najaf Abadi, Mohsen Lotfi, Mohamad Rashno
This study was conducted to investigate the prevalence of subclinical mastitis caused by Staphylococcus spp. in ewes in West-Azerbaijan province of Iran. Molecular characterization of isolated Staphylococcus spp. from diseased ewes were performed using polymerase chain reaction (PCR) followed by restriction fragment length polymorphism (RFLP) and DNA sequencing of glyceraldehyde-3-phosphate dehydrogenase (gap) gene. Also, antibiotic resistance of staphylococcal isolates against different antibiotics was investigated...
2016: Veterinary Research Forum
https://www.readbyqxmd.com/read/27872721/the-role-of-fibroblast-growth-factor-receptor-2-fgfr2-in-differentiation-of-bovine-spermatogonial-stem-cells-scc
#19
Rahem Khoshbakht, Mohammad Tabatabaei, Saeid Hoseinzadeh, Mojtaba Mojtaba, Hesamaddin Shirzad Aski, Enayat Berizi
Although poultry meat is considered as the main source for human Campylobacter infections, there is limited information about non-poultry sources. The present study was aimed to investigate the prevalence and the antibiotic resistance of thermophilic Campylobacter spp. in fecal samples of the cattle and sheep in Shiraz, Iran. A total of 302 fecal samples were obtained from clinically healthy, slaughtered cattle and sheep from Shiraz slaughterhouse. The animals were clinically healthy before being slaughtered...
2016: Veterinary Research Forum
https://www.readbyqxmd.com/read/27855522/melatonin-mitigates-neomycin-induced-hair-cell-injury-in-zebrafish
#20
Kyoung Ho Oh, Yoon Chan Rah, Kyu Ho Hwang, Seung Hoon Lee, Soon Young Kwon, Jae Hyung Cha, June Choi
CONTEXT: Ototoxicity due to medications, such as aminoglycosides, is irreversible, and free radicals in the inner ear are assumed to play a major role. Because melatonin has an antioxidant property, we hypothesize that it might mitigate hair cell injury by aminoglycosides. OBJECTIVE: The objective of this study was to evaluate whether melatonin has an alleviative effect on neomycin-induced hair cell injury in zebrafish (Danio rerio). METHODS: Various concentrations of melatonin were administered to 5-day post-fertilization zebrafish treated with 125 μM neomycin for 1 h...
November 18, 2016: Drug and Chemical Toxicology
keyword
keyword
17794
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"