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https://www.readbyqxmd.com/read/29786940/glycoinformatics-bridging-isolated-islands-in-the-sea-of-data
#1
Ksenia S Egorova, Philip V Toukach
Glycoinformatics is a young scientific branch, which assists the scientific community in carbohydrate research. In spite of fundamental roles of glycans in living organisms, the informatization of the field is significantly hindered by the lack of standards, data indices, protocols and tools widely recognized by researchers and publishers. The connection of the existing glycoinformatics projects with each other and with global life-science projects is far from complete. Moreover, in contrast to genes and proteins, there is no obligatory unique identifier for each natural carbohydrate structure...
May 22, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29784423/microwave-assisted-solid-phase-synthesis-of-highly-fluorescent-carbon-nanoparticles-and-its-application-in-intracellular-ph-sensing
#2
Shenghong Yang, Xiao Chen, Shuqin Liu, Fuxin Wang, Gangfeng Ouyang
Fluorescent carbon nanoparticles (FCNPs) have been deeply researched and widely applied in recent years due to their good optics performance, chemical stability and biocompatibility. Herein, a green and rapid microwave-assisted solid-phase synthesis (solvent-free) approach was proposed for the fabrication of highly FCNPs in a very short period of time, 4 min. The as-prepared FCNPs can emit a blue emission with quantum yield of up to 63.2% in water solution and show yellow fluorescence in the solid state. The FCNPs also exhibit special solvent effect that the fluorescence emission can be adjusted by controlling the solvent ratio of ethanol and water...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29782309/in-memoriam-assistant-professor-kre%C3%A5-imir-kostovi%C3%A4-md-phd-16-october-1969-15-october-2017
#3
Branka Marinović
On a Sunday afternoon almost six months ago, we were deeply moved by the news that our Krešimir is no longer with us. The sad news spread from Sarajevo with the speed only most horrible and saddest news can achieve. And everybody who was reached by these news wondered whether it was possible and whether it was true. Because our professor Kostović left us a day before his 48th birthday. Krešimir Kostović was born on the 16th October 1969 in Zagreb, where he completed primary and secondary education. He enrolled at the University of Zagreb School of Medicine in 1988, and got his medical degree in 1995...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29779623/educating-emergency-department-staff-on-the-identification-and-treatment-of-human-trafficking-victims
#4
Steven Donahue, Michael Schwien, Danielle LaVallee
INTRODUCTION: Hospitalization is one of the few circumstances in which the lives of trafficking victims intersect with the general population. Based on survivor testimonies, the majority of human trafficking victims may receive medical treatment in a hospital's emergency department while in captivity. With evidenced-based training, ED personnel have a better opportunity to screen persons who are being trafficked and intervene on their behalf. METHODS: This project examined the efficacy of an innovative, evidence-based online training module (HTEmergency...
May 17, 2018: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/29778554/cumulative-live-birth-rates-after-ivf-in-patients-with-polycystic-ovaries-phenotype-matters
#5
Michel De Vos, Stéphanie Pareyn, Panagiotis Drakopoulos, José M Raimundo, Ellen Anckaert, Samuel Santos-Ribeiro, Nikolaos P Polyzos, Herman Tournaye, Christophe Blockeel
RESEARCH QUESTION: Do cumulative live birth rates (CLBR) vary among women with different polycystic ovary syndrome (PCOS) phenotypes who undergo IVF/intracytoplasmic sperm injection (ICSI) treatment? DESIGN: In this retrospective cohort study, data from 567 patients undergoing an assisted reproductive technology (ART) cycle between January 2010 and December 2015 were collected. Demographical traits, cycle characteristics and clinical and laboratory data were analysed...
May 7, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29778384/association-of-birth-defects-with-the-mode-of-assisted-reproductive-technology-in-a-chinese-data-linkage-cohort
#6
Hui-Ting Yu, Qing Yang, Xiao-Xi Sun, Guo-Wu Chen, Nai-Si Qian, Ren-Zhi Cai, Han-Bing Guo, Chun-Fang Wang
OBJECTIVE: To evaluate the impact of assisted reproductive technology (ART) on the offspring of Chinese population. DESIGN: Retrospective, data-linkage cohort. SETTING: Not applicable. PATIENT(S): Live births resulting from ART or natural conception. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Birth defects coded according to ICD-10. RESULT(S): Births after ART were more likely to be female and multiple births, especially after intracytoplasmic sperm injection (ICSI)...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29778383/in-vitro-fertilization-interpregnancy-interval-and-risk-of-adverse-perinatal-outcomes
#7
Kristin Palmsten, Michael V Homer, Yujia Zhang, Sara Crawford, Russell S Kirby, Glenn Copeland, Christina D Chambers, Dmitry M Kissin, H Irene Su
OBJECTIVE: To compare associations between interpregnancy intervals (IPIs) and adverse perinatal outcomes in deliveries following IVF with deliveries following spontaneous conception or other (non-IVF) fertility treatments. DESIGN: Cohort using linked birth certificate and assisted reproductive technology surveillance data from Massachusetts and Michigan. SETTING: Not applicable. PATIENT(S): 1,225,718 deliveries. INTERVENTION(S): None...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29774174/outpatient-interventions-that-may-enhance-the-care-of-a-patient-with-co-existing-moyamoya-and-down-syndromes
#8
Anita Lwanga, Waldo Herrera, Katya Cruz Madrid, Antony Irungu
Moyamoya vasculopathy is a condition of chronic, progressive occlusion of the distal internal carotid arteries and the Circle of Willis. The resultant ischemia produces compensatory angiogenesis and the growth of a network of collateral blood vessels, which on angiography resemble a "puff of smoke" or "moyamoya" in Japanese. The objective of this case report is to describe the clinical course of a patient with Down and moyamoya syndromes and to enlighten clinicians about strategies that can be taken to enhance the care of similar patients...
March 16, 2018: Curēus
https://www.readbyqxmd.com/read/29773946/utility-of-the-care-dependency-scale-in-predicting-care-needs-and-health-risks-of-elderly-patients-admitted-to-a-geriatric-unit-a-cross-sectional-study-of-200-consecutive-patients
#9
Halina Doroszkiewicz, Matylda Sierakowska, Marta Muszalik
Objective: The aim of the study was to evaluate the usefulness of the Polish version of the Care Dependency Scale (CDS) in predicting care needs and health risks of elderly patients admitted to a geriatric unit. Methods: This was a cross-sectional study of 200 geriatric patients aged ≥60 years, chronologically admitted to a geriatrics unit in Poland. The study was carried out using the Polish version of the CDS questionnaire to evaluate biopsychosocial needs and the level of care dependency...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29773431/preoperative-frailty-assessment-predicts-loss-of-independence-after-vascular-surgery
#10
Graham W Donald, Amir A Ghaffarian, Farid Isaac, Larry W Kraiss, Claire L Griffin, Brigitte K Smith, Mark R Sarfati, Julie L Beckstrom, Benjamin S Brooke
OBJECTIVE: Frailty, a clinical syndrome associated with loss of metabolic reserves, is prevalent among patients who present to vascular surgery clinics for evaluation. The Clinical Frailty Scale (CFS) is a rapid assessment method shown to be highly specific for identifying frail patients. In this study, we sought to evaluate whether the preoperative CFS score could be used to predict loss of independence after major vascular procedures. METHODS: We identified all patients living independently at home who were prospectively assessed using the CFS before undergoing an elective major vascular surgery procedure (admitted for >24 hours) at an academic medical center between December 2015 and December 2017...
May 14, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29764317/generatehope-a-comprehensive-treatment-model-for-sex-trafficked-women
#11
Susan Munsey, Heather E Miller, Terence Rugg
GenerateHope (GH) is a San Diego-based 501c3 nonprofit organization providing fully integrated, comprehensive rehabilitation services to adult female survivors of sex trafficking. While best practices for working with survivors of sex trafficking are slowly emerging, to date, there have been few publications on this subject and little data on either short- or long-term outcomes from the many and varied programs nationwide. This paper examines the GH residential program and provides early outcome results for residents living at the GH program between six and 12 months...
May 15, 2018: Journal of Evidence-informed Social Work
https://www.readbyqxmd.com/read/29761426/predictors-of-self-reported-adherence-to-direct-oral-anticoagulation-in-a-population-of-elderly-men-and-women-with-non-valvular-atrial-fibrillation
#12
Andrea P Rossi, Roberto Facchinetti, Elena Ferrari, Nicole Nori, Selena Sant, Elena Masciocchi, Elena Zoico, Francesco Fantin, Gloria Mazzali, Mauro Zamboni
There is a general lack of studies evaluating medication adherence with self-report scales for elderly patients in treatment with direct oral anticoagulants (DOACs). The aim of the study was to assess the degree of adherence to DOAC therapy in a population of elderly outpatients aged 65 years or older affected by non-valvular atrial fibrillation (NVAF), using the 4-item Morisky Medication Adherence Scale, and to identify potential factors, including the geriatric multidimensional evaluation, which can affect adherence in the study population...
May 14, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29758575/-descriptive-analysis-of-health-economics-of-intensive-home-care-of-ventilated-patients
#13
Yvonne Lehmann, Julia Ostermann, Thomas Reinhold, Michael Ewers
INTRODUCTION: Long-term ventilated patients in Germany receive intensive care mainly in the patients' home or in assisted-living facilities. There is a lack of knowledge about the nature and extent of resource use and costs associated with care of this small, heterogeneous but overall growing patient group. METHODS: A sub-study in the context of a research project SHAPE analyzed costs of 29 patients descriptively from a social perspective. Direct and indirect costs of intensive home care over a period of three months were recorded and analyzed retrospectively...
May 14, 2018: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29757928/understanding-of-information-about-medicines-use-among-parents-of-pre-school-children-in-serbia-parental-pharmacotherapy-literacy-questionnaire-pthl-sr
#14
Stana Ubavić, Nataša Bogavac-Stanojević, Aleksandra Jović-Vraneš, Dušanka Krajnović
Parental health literacy plays an important role in children’s health, Experiences from pharmacy practice show that is necessary to check if parents understand instructions about use of medicines for children. This study aimed to assess pharmacotherapy literacy of parents of pre-school children and to examine association of parental pharmacotherapy literacy level with parent’s socio-demographic characteristics. The study was cross-sectional, conducted among parents of pre-school children (1⁻7 years of age), in kindergartens in several municipalities of Belgrade, Serbia, during regular parents meetings, from May to October 2016...
May 14, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29757774/can-telerehabilitation-games-lead-to-functional-improvement-of-upper-extremities-in-individuals-with-parkinson-s-disease
#15
Imre Cikajlo, Alma Hukić, Irena Dolinšek, Dejana Zajc, Mateja Vesel, Tatjana Krizmanič, Bojan Blažica, Anton Biasizzo, Franc Novak, Karmen Peterlin Potisk
Parkinson's disease (PD) is treated by medication, less with deep brain stimulation and physiotherapy. Different opinions on the clinical meaningfulness of the physiotherapy or recommended intensive physiotherapy were found. Our objectives were to design intensive target-based physiotherapy for upper extremities suitable for telerehabilitation services and examine the clinical meaningfulness of the exergaming at an unchanged medication plan. A telerehabilitation exergaming system using the Kinect sensor was developed; 28 patients with PD participated in the study...
May 4, 2018: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/29757682/a-scoping-review-of-the-nature-and-outcomes-of-extended-rehabilitation-programmes-after-very-severe-brain-injury
#16
Lucy Knox, Jacinta M Douglas
PRIMARY OBJECTIVE: Many adults with very severe acquired brain injury (ABI) do not receive adequate rehabilitation, limiting their recovery and leading to admission to inappropriate living environments. The aim of this scoping review was to map the existing literature relating to the nature and outcomes of rehabilitation programmes for adults experiencing prolonged recovery after very severe ABI. DESIGN: A comprehensive scoping of the literature was undertaken, including systematic searching of databases, grey literature, and hand searching...
May 14, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29757581/transmyometrial-embryo-transfer-as-a-useful-method-to-overcome-difficult-embryo-transfers-a-single-center-retrospective-study
#17
Janisse Ferreri Dos Anjos, Emma Gabriela Portillo Osorio, Joana Peñarrubia, Ester Vidal, Francisco Fábregues Gasol
OBJECTIVE: Pregnancy after an embryo transfer depends largely on embryo quality, endometrial receptivity, and the technique used in the embryo transfer. Embryo transfers have been reported as inevitably traumatic and difficult for 5-7% of patients in assisted reproduction treatment. In these cases, transmyometrial embryo transfer should be considered as a suitable method to overcome difficult embryo transfers. The aim of this study was to report our experience with this technique and analyze its causes, results and complications...
May 14, 2018: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/29756550/chronic-disease-self-management-challenges-among-rural-women-living-with-hiv-aids-in-prakasam-andhra-pradesh-india-a-qualitative-study
#18
Benissa E Salem, Yvita Bustos, Chidyaonga Shalita, Jordan Kwon, Padma Ramakrishnan, Kartik Yadav, Maria L Ekstrand, Sanjeev Sinha, Adeline M Nyamathi
Rural women living with HIV/AIDS (WLHA) in India experience challenges self-managing HIV/AIDS in their rural communities. The purpose of this qualitative study was to explore factors influencing their care and antiretroviral treatment (ART) adherence. Themes that emerged from the qualitative focus groups among WLHA (N = 24) in rural Prakasam, Andhra Pradesh, India, included: (1) coming to know about HIV and other health conditions, (2) experiences being on ART, (3) challenges maintaining a nutritious diet, (4) factors affecting health care access and quality, and (5) seeking support for a better future...
January 2018: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/29753922/beckwith-wiedemann-syndrome-a-population-based-study-on-prevalence-prenatal-diagnosis-associated-anomalies-and-survival-in-europe
#19
Ingeborg Barisic, Ljubica Boban, Diana Akhmedzhanova, Jorieke E H Bergman, Clara Cavero-Carbonell, Ieva Grinfelde, Anna Materna-Kiryluk, Anna Latos-Bielenska, Hanitra Randrianaivo, Natalya Zymak-Zakutnya, Ivona Sansovic, Monica Lanzoni, Joan K Morris
Beckwith Wiedemann syndrome is a complex developmental disorder characterized by somatic overgrowth, macroglossia, abdominal wall defects, neonatal hypoglycemia, and predisposition to embryonal tumors. We present epidemiological and clinical aspects of patients with Beckwith Wiedemann syndrome diagnosed prenatally or in the early years of life, using data from EUROCAT (European Surveillance of Congenital Anomalies) registries. The study population consisted of 371 cases identified between January 1990 and December 2015 in 34 registries from 16 European countries...
May 10, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29753298/balance-ability-and-cognitive-impairment-influence-sustained-walking-in-an-assisted-living-facility
#20
Mary Elizabeth Bowen, Jeremy Crenshaw, Steven J Stanhope
PURPOSE OF STUDY: The purpose of this study was to determine the influence of cognitive impairment (CI),1 gait quality, and balance ability on walking distance and speed in an assisted living facility. MATERIALS AND METHODS: This was a longitudinal cohort study of institutionalized older adults (N = 26; 555 observations) followed for up to 8 months. Hierarchical linear modeling statistical techniques were used to examine the effects of gait quality and balance ability (using the Tinetti Gait and Balance Test) and cognitive status (using the Montreal Cognitive Assessment) on walking activity (distance, sustained distance, sustained speed)...
May 6, 2018: Archives of Gerontology and Geriatrics
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