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https://www.readbyqxmd.com/read/28545498/feasibility-of-a-systematic-comprehensive-one-to-one-training-scoot-program-for-new-scooter-users-study-protocol-for-a-randomized-control-trial
#1
W Ben Mortenson, Sharon Jang, Charlie H Goldsmith, Laura Hurd Clarke, Sandra Hobson, Richelle Emery
BACKGROUND: Mobility scooters can facilitate community participation among individuals with mobility limitations. However, accidents are a serious concern with scooter use. Scooter training has been recommended to improve safety, but there are currently few validated programs available. Therefore, we developed a Systematic, Comprehensive, One-to-One Training (SCOOT) program for scooter users. We will conduct a study to evaluate the outcomes produced by the provision SCOOT. METHODS: This feasibility study will use a mixed-methods, rater-blinded, randomized control trial, with a two-step wedge design...
May 25, 2017: Trials
https://www.readbyqxmd.com/read/28541832/design-and-development-of-the-first-exoskeletal-garment-to-enhance-arm-mobility-for-children-with-movement-impairments
#2
Martha L Hall, Michele A Lobo
Children with a variety of diagnoses have impairments that limit their arm function. Despite the fact that arm function is important for early learning and activities of daily living, there are few tools to assist movement for these children, and existing devices have challenges related to cost, accessibility, comfort, and aesthetics. In this article, we describe the design process and development of the first garment-based exoskeleton to assist arm movement in young children with movement impairments: the Playskin Lift(TM)...
May 25, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28528510/immunogenomics-using-genomics-to-personalize-cancer-immunotherapy
#3
Rance C Siniard, Shuko Harada
While the use of genomic data has the potential to revolutionize patient care, there is still much work to be done with regard to the transformation of host-tumor interactions into favorable clinical outcomes for our patients. High-throughput technologies, such as next-generation sequencing (NGS), have rapidly advanced our understanding of oncology, and we are learning that most tumors do not simply possess consistently mutated genes that are responsible for tumorigenesis, facilitating the need for personalized cancer therapy...
May 20, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28511066/deep-image-mining-for-diabetic-retinopathy-screening
#4
Gwenolé Quellec, Katia Charrière, Yassine Boudi, Béatrice Cochener, Mathieu Lamard
Deep learning is quickly becoming the leading methodology for medical image analysis. Given a large medical archive, where each image is associated with a diagnosis, efficient pathology detectors or classifiers can be trained with virtually no expert knowledge about the target pathologies. However, deep learning algorithms, including the popular ConvNets, are black boxes: little is known about the local patterns analyzed by ConvNets to make a decision at the image level. A solution is proposed in this paper to create heatmaps showing which pixels in images play a role in the image-level predictions...
April 28, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28510572/1-2-million-kids-and-counting-mobile-science-laboratories-drive-student-interest-in-stem
#5
Amanda L Jones, Mary K Stapleton
In today's increasingly technological society, a workforce proficient in science, technology, engineering, and mathematics (STEM) skills is essential. Research has shown that active engagement by K-12 students in hands-on science activities that use authentic science tools promotes student learning and retention. Mobile laboratory programs provide this type of learning in schools and communities across the United States and internationally. Many programs are members of the Mobile Lab Coalition (MLC), a nonprofit organization of mobile and other laboratory-based education programs built on scientist and educator collaborations...
May 2017: PLoS Biology
https://www.readbyqxmd.com/read/28510500/using-big-data-to-guide-implementation-of-a-web-and-mobile-adaptive-learning-platform-for-medical-students
#6
Ashwin Menon, Shiv Gaglani, M Ryan Haynes, Sean Tackett
BACKGROUND: Adaptive learning platforms (ALPs) can revolutionize medical education by making learning more efficient, but their potential has not been realized because students do not use them persistently. METHODS: We applied educational data mining methods to study United States medical students who used an ALP called Osmosis ( www.osmosis.org ) from 1 August 2014 to 31 July 2015. Multivariate logistic regressions modeled persistence on Osmosis as the dependent variable and Osmosis-collected variables as predictors...
May 16, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28508784/vr-medical-gamification-for-training-and-education
#7
Stelian Nicola, Ioan Virag, Lăcrămioara Stoicu-Tivadar
The new virtual reality based medical applications is providing a better understanding of healthcare related subjects for both medical students and physicians. The work presented in this paper underlines gamification as a concept and uses VR as a new modality to study the human skeleton. The team proposes a mobile Android platform application based on Unity 5.4 editor and Google VR SDK. The results confirmed that the approach provides a more intuitive user experience during the learning process, concluding that the gamification of classical medical software provides an increased interactivity level for medical students during the study of the human skeleton...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28505991/lower-extremity-robotic-exoskeleton-training-case-studies-for-complete-spinal-cord-injury-walking
#8
Edward D Lemaire, Andrew J Smith, Andrew Herbert-Copley, Vidya Sreenivasan
BACKGROUND: Recent advances in exoskeleton technology has made lower extremity powered exoskeletons (LEPE) a viable treatment tool to restore upright walking mobility to persons with spinal cord injury (SCI). OBJECTIVE: Evaluate ARKE exoskeleton training within a rehabilitation centre environment. METHODS: Case studies are presented for two male participants, age 41 and 30, motor complete SCI at T6 (N01) and T12 (N02), respectively, as they progress from new LEPE users to independent walking...
May 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28504324/electromagnetic-fields-pulsed-radiofrequency-radiation-and-epigenetics-how-wireless-technologies-may-affect-childhood-development
#9
Cindy Sage, Ernesto Burgio
Mobile phones and other wireless devices that produce electromagnetic fields (EMF) and pulsed radiofrequency radiation (RFR) are widely documented to cause potentially harmful health impacts that can be detrimental to young people. New epigenetic studies are profiled in this review to account for some neurodevelopmental and neurobehavioral changes due to exposure to wireless technologies. Symptoms of retarded memory, learning, cognition, attention, and behavioral problems have been reported in numerous studies and are similarly manifested in autism and attention deficit hyperactivity disorders, as a result of EMF and RFR exposures where both epigenetic drivers and genetic (DNA) damage are likely contributors...
May 15, 2017: Child Development
https://www.readbyqxmd.com/read/28503549/learning-from-mother-nature-innovative-tools-to-boost-endogenous-repair-of-critical-or-difficult-to-heal-large-tissue-defects
#10
REVIEW
Ranieri Cancedda, Sveva Bollini, Fiorella Descalzi, Maddalena Mastrogiacomo, Roberta Tasso
For repair of chronic or difficult-to-heal tissue lesions and defects, major constraints exist to a broad application of cell therapy and tissue engineering approaches, i.e., transplantation of "ex vivo" expanded autologous stem/progenitor cells, alone or associated with carrier biomaterials. To enable a large number of patients to benefit, new strategies should be considered. One of the main goals of contemporary regenerative medicine is to develop new regenerative therapies, inspired from Mother Nature. In all injured tissues, when platelets are activated by tissue contact, their released factors promote innate immune cell migration to the wound site...
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/28502359/pearls-and-pitfalls-for-a-surgeon-new-to-ankle-replacements
#11
REVIEW
Federico Giuseppe Usuelli, Camilla Maccario
The role of the surgeon learning curve in total ankle replacement (TAR) has produced contradictory results. It is important for a new surgeon to know what clinical and radiological parameters are considered reliable and ideal. It is clear that exposure to a high-volume center will increase the reliability of a new surgeon approaching TAR. Implant choice may be influenced by surgeon training, and the debate of mobile versus fix-bearing prosthesis is still open. Anterior versus lateral approach is still an open debate, with any hypothetical advantages given by the direct vision on the center of rotation to be proven...
June 2017: Foot and Ankle Clinics
https://www.readbyqxmd.com/read/28502184/promoting-community-malaria-control-in-rural-myanmar-through-an-active-community-participation-program-using-the-participatory-learning-approach
#12
Chan Nyein Maung, Than Tun Sein, Thaung Hlaing, Kamolnetr Okanurak, Tassanee Silawan, Jaranit Kaewkungwal
INTRODUCTION: Malaria is prevalent in more than 80% of townships in Myanmar. The National Malaria Control Programme (NMCP) has been implementing community-based malaria control programs nationwide. However, these programs are mostly developed and directed by health authorities, while communities are passively involved. This study aimed to increase community participation in malaria control and promote community malaria control knowledge and practice in rural Myanmar. METHODS: A community-based study, which employed a mixed method approach, collecting data quantitatively and qualitatively, was conducted in two rural villages...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28492731/brazilian-scientific-mobility-program-science-without-borders-preliminary-results-and-perspectives
#13
Concepta McManus, Carlos A Nobre
The Brazilian Scientific Mobility Program - Science without Borders (SwB) - saw the concession of over 101 thousand scholarships for Brazilian STEM students and education professionals to attend universities worldwide. As the first phase of this program ends, it is time to take a first look at its impacts, mainly on the undergraduate student body (79% of total scholarships implemented). Benefits included a 6-month language course (optional), a one year undergraduate course and optional 2 month internship in a university, government laboratory or technology company...
May 4, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28490322/the-effects-of-video-game-therapy-on-balance-and-attention-in-chronic-ambulatory-traumatic-brain-injury-an-exploratory-study
#14
Sofia Straudi, Giacomo Severini, Amira Sabbagh Charabati, Claudia Pavarelli, Giulia Gamberini, Anna Scotti, Nino Basaglia
BACKGROUND: Patients with traumatic brain injury often have balance and attentive disorders. Video game therapy (VGT) has been proposed as a new intervention to improve mobility and attention through a reward-learning approach. In this pilot randomized, controlled trial, we tested the effects of VGT, compared with a balance platform therapy (BPT), on balance, mobility and selective attention in chronic traumatic brain injury patients. METHODS: We enrolled chronic traumatic brain injury patients (n = 21) that randomly received VGT or BPT for 3 sessions per week for 6 weeks...
May 10, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28485102/a-web-based-peer-feedback-tool-for-physical-examination
#15
Ryan Luther, Lisa Richardson
BACKGROUND: Medical students do not have many formal opportunities to practise physical examinations during their pre-clerkship years. Consequently, they often practise their examination skills with peers outside of formal teaching sessions. There are also few opportunities for observation and feedback on their skills in this area. CONTEXT: The undergraduate medical programme at the University of Toronto is a 4-year programme where students learn clinical skills in the first 2 years prior to beginning clinical rotations...
May 9, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28480476/the-role-of-free-libre-and-open-source-software-in-learning-health-systems
#16
C Paton, T Karopka
OBJECTIVE: To give an overview of the role of Free/Libre and Open Source Software (FLOSS) in the context of secondary use of patient data to enable Learning Health Systems (LHSs). METHODS: We conducted an environmental scan of the academic and grey literature utilising the MedFLOSS database of open source systems in healthcare to inform a discussion of the role of open source in developing LHSs that reuse patient data for research and quality improvement. RESULTS: A wide range of FLOSS is identified that contributes to the information technology (IT) infrastructure of LHSs including operating systems, databases, frameworks, interoperability software, and mobile and web apps...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28479353/some-lessons-learned-from-a-comparison-between-sedimentation-velocity-analytical-ultracentrifugation-and-size-exclusion-chromatography-to-characterize-and-quantify-protein-aggregates
#17
Aditya V Gandhi, Mark R Pothecary, David L Bain, John F Carpenter
There are numerous problems with size exclusion chromatography (SEC), which often lead to inaccuracies in protein aggregate characterization. Hence, this study tested sedimentation velocity analytical ultracentrifugation (SV-AUC) as an orthogonal tool to SEC for quantifying the monomer and aggregates in intravenous immunoglobulin (IVIg) formulations. IVIg samples were subjected to agitation stress and analyzed using SEC mobile phases composed of 200 mM sodium phosphate (pH 7.0) with 0, 50, 100, 200 or 400 mM of NaCl...
May 4, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28476122/sex-differences-in-avoidance-behavior-after-perceiving-potential-risk-in-mice
#18
Sayaka Yokota, Yusuke Suzuki, Keigo Hamami, Akiko Harada, Shoji Komai
BACKGROUND: Sex has been considered as a potential factor regulating individual behaviors in different contexts. Recently, findings on sex differences in the neuroendocrine circuit have expanded due to exact measurements and control of neuronal activity, while findings on sex differences in behavioral phenotypes are limited. One efficient way to determine the miscellaneous aspects of a sexually different behavior is to segment it into a set of simpler responses induced by discrete scenes...
May 5, 2017: Behavioral and Brain Functions: BBF
https://www.readbyqxmd.com/read/28473258/representational-specializations-of-the-hippocampus-in-phylogenetic-perspective
#19
REVIEW
Elisabeth A Murray, Steven P Wise, Kim S Graham
In a major evolutionary transition that occurred more than 520 million years ago, the earliest vertebrates adapted to a life of mobile, predatory foraging guided by distance receptors concentrated on their heads. Vision and olfaction served as the principal sensory systems for guiding their search for nutrients and safe haven. Among their neural innovations, these animals had a telencephalon that included a homologue of the hippocampus. Experiments on goldfish, turtles, lizards, rodents, macaque monkeys and humans have provided insight into the initial adaptive advantages provided by the hippocampus homologue...
May 1, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28472351/the-benefits-and-limitations-of-targeted-training-in-flexible-transnasal-laryngoscopy-diagnosis
#20
Kimberly A Russell, Christopher D Brook, Michael P Platt, Gregory A Grillone, Avner Aliphas, J Pieter Noordzij
Importance: Targeted laryngoscopy training can be used successfully in de novo learners. Objective: To determine the value of targeted laryngoscopy education in interns. Design, Setting, and Participants: This prospective study of fiberoptic laryngoscopy interpretations enrolled 13 participants in an academic hospital setting from August 1 to December 31, 2015. Participants included 10 postgraduate year 1 emergency and otolaryngology interns and 3 board-certified otolaryngology attending physicians...
May 4, 2017: JAMA Otolaryngology—Head & Neck Surgery
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