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https://www.readbyqxmd.com/read/29334677/utilizing-journal-club-to-facilitate-critical-thinking-in-pre-clinical-medical-students
#1
Victoria C Lucia, Stephanie M Swanberg
No abstract text is available yet for this article.
January 15, 2018: International Journal of Medical Education
https://www.readbyqxmd.com/read/29334598/time-to-re-think-fungal-ecology-fungal-ecological-niches-are-often-prejudged
#2
Marc-André Selosse, Laure Schneider-Maunoury, Florent Martos
No abstract text is available yet for this article.
February 2018: New Phytologist
https://www.readbyqxmd.com/read/29334045/development-of-a-patient-experience-questionnaire-to-improve-lifestyle-services-in-primary-care
#3
Paula Brauer, Dawna Royall, Anneli Kaethler, Alexandra Mayhew, Maya Israeloff-Smith
Aim We developed a self-report tool to assess patients' experiences with lifestyle services in team-based primary care and pilot tested the questionnaire as part of a lifestyle intervention study to reverse metabolic syndrome. BACKGROUND: Older client satisfaction questionnaires have been generally inadequate for quality improvement purposes, as they have been focused mainly on interpersonal skills of providers and/or in the context of one disease. New approaches to assessing the patient experience of lifestyle programs in primary care are needed and could inform quality improvement efforts over time...
January 15, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29333500/improving-the-written-medical-handover
#4
Rhys Martin, Melanie Huddart, Cara Garbett, Wendell Storr, Olivia Watts, Sanjeev Gupta
The handover of large numbers of medical patients, during on call periods when staffing levels are reduced, is a challenge for all acute medical services. At the Royal Cornwall Hospital, a large district general hospital, we identified that foundation doctors were reviewing medical inpatients during weekend on call periods with limited written handover information. We chose to address this problem by developing an intervention, a weekend handover sticker, and piloting it. We used the review of documentation to measure improvement and feedback from users to assess the processes involved...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29332579/alzheimer-s-disease-a-systemic-review-of-substantial-therapeutic-targets-and-the-leading-multi-functional-molecules
#5
Tarana Umar, Nasimul Hoda
Alzheimer's disease (AD) is a fatal neurodegenerative disorder, having a complex aetiology with numerous possible drug targets. There are targets that have been known for years while more new targets and theories have also emerged. Beta amyloid and cholinesterases are the most significant biological targets for finding curative treatment of AD. The major class of drugs used for AD till now has been the Cholinesterase (ChE) inhibitors. Other prevailing models of molecular pathogenesis in AD include neurofibrillary tangles (NFTs) and amyloid deposition, tryptophan degradation pathway, kinase and phosphatase activity imbalance and neuroinflammation...
January 12, 2018: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/29332555/victim-empowerment-safety-and-perpetrator-accountability-through-collaboration-a-crisis-to-transformation-conceptual-model
#6
Jacquelyn W White, Holly C Sienkiewicz
This article describes the development of the Victim Empowerment, Safety, and Perpetrator Accountability through Collaboration (VESPAC) model based on a grounded theory analysis of congressionally mandated and permissible purpose areas for grants authorized by the Violence Against Women Act. These areas are reflective of ongoing and emerging needs of victims and agencies serving victims and are rooted in the expertise, insight, and concerns of those who work most closely with victims and perpetrators on a regular basis...
December 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29332503/-they-said-on-the-death-certificate%C3%A2-but-really-what-i-think-happened-characterizing-cause-of-death-in-va-medical-centers
#7
Beverly Rosa Williams, F Amos Bailey, Patricia S Goode, Kathryn L Burgio
Cause of death information is a vital resource for family and public health, yet significant issues persist regarding its determination, documentation and communication. In this study, we aim to characterize cause of death attribution process from the perspective of next-of-kin of Veterans who died in Veterans Affairs (VA) Medical Centers. Using a semi-structured guide, we explored next-of-kin's experiences of the Veteran's terminal hospitalization and conducted a content analysis of interview texts. In over two-third of cases next-of-kin's understanding was not consistent with their recollection of physicians' determination of cause of death...
January 1, 2018: Journal of Palliative Care
https://www.readbyqxmd.com/read/29332175/breast-cancer-survivor-s-perspectives-on-the-role-different-providers-play-in-follow-up-care
#8
J L Tucholka, N Jacobson, N M Steffens, J R Schumacher, A J Tevaarwerk, B Anderson, L G Wilke, C C Greenberg, Heather B Neuman
IMPORTANCE: Significant variation in the number and types of oncologists that provide breast cancer follow-up exists. However, there is limited understanding regarding breast cancer survivors' preferences for who provides their follow-up. Our objective was to explore breast cancer survivors' perspectives on the goals of breast cancer follow-up, the preferred role for primary care providers, and the perceived roles of different types of oncologists during follow-up. METHODS: A convenience sample of stage 0-III breast cancer survivors was identified and in-depth one-on-one interviews conducted...
January 13, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29332117/pseudocholinesterase-levels-in-patients-under-electroconvulsive-therapy
#9
Gamze Küçükosman, Özcan Pişkin, Volkan Hancı, Rahşan D Okyay, Hilal Ayoğlu, Bülent S Yurtlu, Mehmet Akın, Işıl Ö Turan
In this study, we aimed to retrospectively assess the correlation of pseudocholinesterase (PChE) levels with age, gender, body weight and diagnosed psychiatric diseases in electroconvulsive therapy (ECT) cases. Methods: This retrospective study was conducted at Bülent Ecevit University Hospital, Zonguldak, Turkey, between 2007 and 2011. In the study, 193 ECT case files were retrospectively scanned to evaluate PChE values before ECT and other file information.  Results: There was no difference between gender in terms of PChE levels...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29332039/alzheimer-s-disease-rs11767557-variant-regulates-epha1-gene-expression-specifically-in-human-whole-blood
#10
Guiyou Liu, Yan Zhang, Longcai Wang, Jianyong Xu, Xiaoyun Chen, Yunjuan Bao, Yang Hu, Shuilin Jin, Rui Tian, Weiyang Bai, Wenyang Zhou, Tao Wang, Zhifa Han, Jian Zong, Qinghua Jiang
Large-scale genome-wide association studies have reported EPHA1 rs11767557 variant to be associated with Alzheimer's disease (AD) risk in the European population. However, it is still unclear how this variant functionally contributes to the underlying disease pathogenesis. The rs11767557 variant is located approximately 3 kb upstream of EPHA1 gene. We think that rs11767557 may modify the expression of nearby genes such as EPHA1 and further cause AD risk. Until now, the potential association between rs11767557 and the expression of nearby genes has not been reported in previous studies...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29331519/understanding-and-misunderstanding-randomized-controlled-trials
#11
Angus Deaton, Nancy Cartwright
Randomized Controlled Trials (RCTs) are increasingly popular in the social sciences, not only in medicine. We argue that the lay public, and sometimes researchers, put too much trust in RCTs over other methods of investigation. Contrary to frequent claims in the applied literature, randomization does not equalize everything other than the treatment in the treatment and control groups, it does not automatically deliver a precise estimate of the average treatment effect (ATE), and it does not relieve us of the need to think about (observed or unobserved) covariates...
December 25, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29331248/usability-evaluation-of-a-commercial-inpatient-portal
#12
Po-Yin Yen, Daniel M Walker, Jessica M Garvey Smith, Michelle P Zhou, Terri L Menser, Ann Scheck McAlearney
OBJECTIVES: Patient portals designed for inpatients have potential to increase patient engagement. However, little is known about how patients use inpatient portals. To address this gap, we aimed to understand how users 1) interact with, 2) learn to use, and 3) communicate with their providers through an inpatient portal. MATERIALS AND METHODS: We conducted a usability evaluation using think-aloud protocol to study user interactions with a commercially available inpatient portal - MyChart Bedside (MCB)...
February 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29330864/allergy-committed-to-progress-in-allergy-and-immunology
#13
Hans-Uwe Simon, Thomas Bieber
After more than 8 years, our terms as Co-Editors-in-Chief have now reached an end. We are thankful for having had the privilege to serve the community in this position. We think that we have reached our original goal of increasing the overall quality of the journal (1). The science which is reported every month in Allergy is of high quality and wide interest, largely contributing to the development of the fields of Allergy and Immunology. The impact of the journal is high, as reflected by its present impact factor of 7...
January 13, 2018: Allergy
https://www.readbyqxmd.com/read/29330088/the-flight-of-the-locus-of-selection-some-intricate-relationships-between-evolutionary-elements
#14
REVIEW
April M Becker
Selection has enriched our understanding of the world since it was first applied to the evolution of species. Selection stands as an alternative to essentialist thinking, as a generalized and multiply applicable concept, and as a causal explanation for current forms within biology and behavior. Attempts to describe selection processes in a generalizable way have provided clarity about their minimal elements, such as replicators and interactors. This paper discusses the interconnectedness among different levels of selection using evidence garnered from evolutionary biology, development, epigenetics, neuroscience, and behavior analysis...
January 9, 2018: Behavioural Processes
https://www.readbyqxmd.com/read/29329440/executive-function-and-internalizing-symptoms-in-adolescents-and-young-adults-with-congenital-heart-disease-the-role-of-coping
#15
Jamie L Jackson, Gina M Gerardo, Jennifer D Monti, Kyle A Schofield, Kathryn Vannatta
Executive functioning deficits have been documented among congenital heart disease (CHD) survivors and may contribute to emotional distress. Little research has investigated the role of coping in this association. This study examined the role of coping in accounting for the association between self-reported executive function problems and internalizing symptoms among adolescents and emerging adults (AEAs), as well as young adults (YAs) with CHD. Participants included 74 AEA ( M age  = 19.32  ±  3.47 years, range 15-25 years) and 98 YA CHD survivors ( M age  = 32...
January 10, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29329064/user-acceptability-of-the-diagnosis-of-prolonged-grief-disorder-how-do-professionals-think-about-inclusion-in-icd-11
#16
Leonie Dietl, Birgit Wagner, Thomas Fydrich
BACKGROUND: For the next edition of the International Statistical Classification of Diseases (ICD-11) it is proposed to include prolonged grief disorder as a new diagnosis. The diagnosis describes persistent intensive and disabling grief reactions to bereavement (WHO, 2016b). The aim of the present survey was to determine the extent to which the diagnosis is accepted by practitioners in the healthcare and psychosocial field. METHODS: A total of 2088 German-speaking professionals in the fields of psychotherapy, psychology, counselling, medicine and palliative care completed the online survey...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29328962/so-you-think-computational-approaches-to-understanding-glycosaminoglycan-protein-interactions-are-too-dry-and-too-rigid-think-again
#17
REVIEW
Nehru Viji Sankaranarayanan, Balaji Nagarajan, Umesh R Desai
Glycosaminoglycans (GAGs) play key roles in virtually all biologic responses through their interaction with proteins. A major challenge in understanding these roles is their massive structural complexity. Computational approaches are extremely useful in navigating this bottleneck and, in some cases, the only avenue to gain comprehensive insight. We discuss the state-of-the-art on computational approaches and present a flowchart to help answer most basic, and some advanced, questions on GAG-protein interactions...
January 9, 2018: Current Opinion in Structural Biology
https://www.readbyqxmd.com/read/29328948/psychopathology-and-episodic-future-thinking-a-systematic-review-and-meta-analysis-of-specificity-and-episodic-detail
#18
D J Hallford, D W Austin, K Takano, F Raes
Episodic future thinking (EFT) refers to the mental simulation of future events that might be personally-experienced; a crucial mental process in adaptation. Psychiatric disorders are associated with deficits in recalling episodic memory, however, no study has reviewed the empirical literature to assess for similar deficits in EFT. A systematic review comparing psychiatric groups with control groups on the specificity and episodic detail of EFT returned 19 eligible studies. An overall effect of g = -0.84 (95%CI = -1...
January 5, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29328947/evaluating-the-role-of-repetitive-negative-thinking-in-the-maintenance-of-social-appearance-anxiety-an-experimental-manipulation
#19
Erin E Reilly, Elana B Gordis, James F Boswell, Joseph M Donahue, Stephanie M Emhoff, Drew A Anderson
Social appearance anxiety (SAA), or fear of having one's appearance negatively evaluated by others, is a risk factor for eating pathology and social anxiety, but maintenance processes for SAA remain unclear. The current study evaluated repetitive negative thinking (RNT) as a process through which SAA is maintained over time. Undergraduates (N = 126) completed self-report measurements, made an impromptu speech task to induce SAA, and were randomized to either engage in RNT or distraction following the speech task...
January 5, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29328906/importance-of-information-provision-in-the-acceptance-of-blood-donation-criteria-by-the-general-public-in-belgium
#20
Bert Avau, Emmy De Buck, Philippe Vandekerckhove, Veerle Compernolle
BACKGROUND: Blood transfusions save lives, but carry the risk of causing transfusion-transmitted diseases. This risk is limited by strict donor selection criteria, the most controversial being the exclusion of men who had sex with men (MSM). This cross-sectional study investigated knowledge and beliefs of the general public concerning donor exclusion criteria, with emphasis on MSM. MATERIALS AND METHODS: A representative sample of the population of Flanders, Belgium was questioned using a web-based questionnaire...
November 27, 2017: Blood Transfusion, Trasfusione del Sangue
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