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Claire S Allardyce, Paul J Dyson, Michael Grätzel
Undoubtedly, reducing vector populations or their interactions with hosts below a critical level is a practical and proven method of disease control. Introduction of insecticide-treated bed nets has significantly reduced malaria in some parts of the world. However, for many reasons, implementation of such strategies is challenging and the protection offered by particular products limited: bed nets are only effective during sleep. Other methods have been launched, but low customer appeal, high cost, low specificity, and lack of sustainability and effectiveness are often reasons for failure...
October 2016: Chimia
Mirja Ruohoniemi, Johanna Mikkonen, Riitta Salomäki, Laura Hänninen, Annamari Heikkilä, Sanna Ryhänen
During the last decade, concerns over veterinary students' stress have been expressed in several studies, and the need for student support has become evident. In addition, the importance of professional and personal identity development in veterinary curricula has been widely recognized. There is a need to integrate academic and professional skills instruction with training in personal-life balance. Even though tools for student support and stress management exist within universities, reports on active and creative practices in veterinary education are scarce...
October 25, 2016: Journal of Veterinary Medical Education
Hellen J Amuguni, Melissa Mazan, Robert Kibuuka
Infectious diseases of grave concern to human health are emerging from wildlife and livestock populations in multiple regions of the world. Responding effectively to these emerging pandemics requires engagement of multidisciplinary groups of professionals. Using a One Health approach, One Health Central and Eastern Africa (OHCEA), a network of seven schools of public health and seven veterinary schools, with the support of the United States Agency for International Development (USAID), has engaged in curriculum review with the aim of building the skills of multidisciplinary groups of professionals to improve their capacity to respond to emerging infectious diseases...
October 25, 2016: Journal of Veterinary Medical Education
Hai-Han Liao, Xu-Hui Jia, Huang-Jun Liu, Yang Zheng, Tang Qizhu
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors involved in the regulation of lipid metabolism, energy production, and inflammation. It is well established that all of the three isoforms of PPARs expressed in the cardiomyocytes, and that PPARs are closely involved in the regulation of lipid metabolism and energy homeostasis as well as many other different aspects in the heart. We think that PPARs are very important therapeutic targets for drug development, however, the drugs targeting at PPARs meet some trouble in clinical practice, especially the reported side effects related to heart failure...
September 28, 2016: Current Pharmaceutical Design
H G Kenngott, M Wagner, A A Preukschas, B P Müller-Stich
Modern operating room (OR) suites are mostly digitally connected but until now the primary focus was on the presentation, transfer and distribution of images. Device information and processes within the operating theaters are barely considered. Cognitive assistance systems have triggered a fundamental rethinking in the automotive industry as well as in logistics. In principle, tasks in the OR, some of which are highly repetitive, also have great potential to be supported by automated cognitive assistance via a self-thinking system...
October 24, 2016: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Nunzio Montelione, Danilo Menna, Pasqualino Sirignano, Laura Capoccia, Wassim Mansour, Francesco Speziale
A 62-year-old man presented with fever, abdominal pain, and malaise 13 months after emergency endovascular aortic repair. Computed tomographic angiograms showed a periprosthetic fluid and gas collection, so infection was diagnosed. Open conversion was performed, involving endograft explantation and in situ aortic reconstruction. Cultures and the explanted prosthesis were positive for carbapenemase-producing Klebsiella pneumoniae, resistant to colistin. Because of the sparse data on endograft infections caused by this pathogen, we placed the patient on an empiric double-carbapenem regimen for 4 weeks...
October 2016: Texas Heart Institute Journal
Didier Lecointe, Jade Assoukpa, Lauriane Cezard, Carole Descaves, Armelle Gouot, Sandrine Bourgeois, Monique Bergeon, Stéphane Koutcherenko, Yasmine Lakhdari, Noura Kassidi
The microbiological tests on breast milk performed when samples of pasteurized breast milk are added to hospital milk banks are covered by French regulations dating from December 3(rd) 2007. They involve counts of the aerobic total flora and of Staphylococcus aureus in a sample of milk before pasteurization, and culture after pasteurization to check that the treated milk is sterile. The regulations specify the nature of the agar plates to be used, together with the conditions for plating and incubation, but they lack detail in other areas...
October 24, 2016: Annales de Biologie Clinique
Pamela Jane Marsh, Vince Polito, Subba Singh, Max Coltheart, Robyn Langdon, Anthony W Harris
BACKGROUND: Impaired ability to make inferences about what another person might think or feel (i.e., social cognition impairment) is recognised as a core feature of schizophrenia and a key determinant of the poor social functioning that characterizes this illness. The development of treatments to target social cognitive impairments as a causal factor of impaired functioning in schizophrenia is of high priority. In this study, we investigated the acceptability, feasibility, and limited efficacy of 2 programs targeted at specific domains of social cognition in schizophrenia: "SoCog" Mental-State Reasoning Training (SoCog-MSRT) and "SoCog" Emotion Recognition Training (SoCog-ERT)...
October 24, 2016: BMC Psychiatry
Matthew Jacobs, Martin Lopez-Garcia, O-Phart Phrathep, Tracy Lawson, Ruth Oulton, Heather M Whitney
Enhanced light harvesting is an area of interest for optimizing both natural photosynthesis and artificial solar energy capture(1,2). Iridescence has been shown to exist widely and in diverse forms in plants and other photosynthetic organisms and symbioses(3,4), but there has yet to be any direct link demonstrated between iridescence and photosynthesis. Here we show that epidermal chloroplasts, also known as iridoplasts, in shade-dwelling species of Begonia(5), notable for their brilliant blue iridescence, have a photonic crystal structure formed from a periodic arrangement of the light-absorbing thylakoid tissue itself...
October 24, 2016: Nature Plants
So Youn Park, Ivo Kwon, In Hwan Oh
When thinking about priority setting in access to healthcare resources, decision-making requires that cost-effectiveness is balanced against medical ethics. The burden of disease has emerged as an important approach to the assessment of health needs for political decision-making. However, the disability adjusted life years approach hides conceptual and methodological issues regarding the claims and value of disabled people. In this article, we discuss ethical issues that are raised as a consequence of the introduction of evidence-based health policy, such as economic evidence, in establishing resource allocation priorities...
November 2016: Journal of Korean Medical Science
Katie M Edwards, Victoria L Banyard, Elizabeth A Moschella, Katherine M Seavey
This study qualitatively examined rural emerging adults' ways of thinking (i.e., lay theories) about the causes of intimate partner violence (IPV) and ideas on how to prevent IPV most effectively. Participants were 74 individuals (majority Caucasian, heterosexual, low income) between the ages of 18 and 24 who resided in one of 16 rural communities. Participants' perceptions of the causes of IPV included (a) individual-level pathology, stress, and lack of education; (b) intergenerational transmission of violence and early-life factors; (c) relationship stressors and challenges; and (d) community factors...
October 24, 2016: American Journal of Community Psychology
Uri Maoz, Gideon Yaffe
A defendant is criminally responsible for his action only if he is shown to have engaged in a guilty act-actus reus (eg for larceny, voluntarily taking someone else's property without permission)-while possessing a guilty mind-mens rea (eg knowing that he had taken someone else's property without permission, intending not to return it)-and lacking affirmative defenses (eg the insanity defense or self-defense). We therefore first review neuroscientific studies that bear on the nature of voluntary action, and so could, potentially, tell us something of importance about the actus reus of crimes...
April 2016: Journal of Law and the Biosciences
Michael A Kraus, Richard J Fluck, Eric D Weinhandl, Sheru Kansal, Michael Copland, Paul Komenda, Fredric O Finkelstein
Diminished health-related quality of life (HRQoL) is common in dialysis patients and associated with increased risks for morbidity and mortality. Patients may present limitations in both physical and mental HRQoL. Poor physical HRQoL may be defined by limited physical function, role limitations due to physical health, dissatisfaction with physical ability, and impaired mobility. Sleep disorders such as obstructive sleep apnea, restless legs, and fatigue are typical manifestations of poor physical HRQoL in dialysis patients...
November 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Jan Baars
Aging and time are interconnected because aging is basically living seen in a temporal perspective. This makes 'time' an important concept in trying to explain aging. However, throughout modernity time has increasingly been identified as clock time: perfectly fit to measure 'age' as time since birth but failing to explain 'age' as an indicator of aging processes and even less adequate to grasp the lived time of human beings. Moreover, the clock as a cultural idol of instrumentalist perfection has led to approaching human aging in terms of maintenance and repair, inspiring a neglect and depreciation of human vulnerability...
October 22, 2016: Biogerontology
Pramod P Jog
No abstract text is available yet for this article.
September 8, 2016: Indian Pediatrics
Sean Page, Ian Davies-Abbott, Mat Phillips
Dementia Care Mapping™ is widely acknowledged as the gold standard observational method that can support the introduction of person centred care into a variety of settings ( It encourages care staff to think about how the person with dementia is experiencing the care provided and the care setting. It has been shown to raise care staff awareness sufficiently to bring about improvements in care. In this paper, we describe a programme of work in North Wales that seeks to find innovative ways to use Dementia Care Mapping™, in acute mental health admission wards for people affected by dementia, and we set out some of those innovations...
October 21, 2016: Dementia
Julio Frenk, Octavio Gómez-Dantés
No abstract text is available yet for this article.
October 19, 2016: Lancet
Chen-Hsiang Yeang, Robert A Beckman
BACKGROUND: Current cancer precision medicine strategies match therapies to static consensus molecular properties of an individual's cancer, thus determining the next therapeutic maneuver. These strategies typically maintain a constant treatment while the cancer is not worsening. However, cancers feature complicated sub-clonal structure and dynamic evolution. We have recently shown, in a comprehensive simulation of two non-cross resistant therapies across a broad parameter space representing realistic tumors, that substantial improvement in cure rates and median survival can be obtained utilizing dynamic precision medicine strategies...
October 22, 2016: Biology Direct
Xiao Wei Tang, Miao Yu, Wei Wei Duan, Xiang Rong Zhang, Wei Wei Sha, Xiang Wang, Xiao Bin Zhang
Deficit schizophrenia (DS) has been proposed as a pathophysiologically distinct schizophrenia subtype. This study investigated facial emotion recognition deficits and alexithymia in DS and non-deficit schizophrenia patients (NDS) and their relationships with other clinical variables. The Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Negative Symptoms (SANS), and Scale for the Assessment of Positive Symptoms (SAPS) were employed to evaluate the psychiatric symptoms in patients with schizophrenia...
September 29, 2016: Psychiatry Research
Abdulkadir Tunç, Belma Doğan Güngen, Ferhat Evliyaoğlu, Yeşim Güzey Aras, Aysel Kaya Tekeşin
The aim of this study was to investigate retinal nerve fiber layer (RNFL), ganglion cell layer (GCL) thickness, macular changes (central subfield thickness (CST), cube average thickness (CAT), cube volume (CV) in patients with migraine using spectral-domain optical coherence tomography (OCT) and to assess if there was any correlation with white matter lesions (WML). In this prospective case-control study, RNFL, GCL thickness and macular changes of 19 migraine patients with aura (MA), 41 migraine without aura (MO) and 60 age- and gender-matched healthy subjects were measured using OCT device...
October 21, 2016: Acta Neurologica Belgica
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