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https://www.readbyqxmd.com/read/29109782/berunda-polypeptides-multi-headed-fusion-proteins-promote-subcutaneous-administration-of-rapamycin-to-breast-cancer-in-vivo
#1
Jugal P Dhandhukia, Zhe Li, Santosh Peddi, Shruti Kakan, Arjun Mehta, David Tyrpak, Jordan Despanie, J Andrew MacKay
Recombinant Elastin-Like Polypeptides (ELPs) serve as attractive scaffolds for nanoformulations because they can be charge-neutral, water soluble, high molecular weight, monodisperse, biodegradable, and decorated with functional proteins. We recently reported that fusion of the FK-506 binding protein 12 (FKBP) to an ELP nanoparticle (FSI) reduces rapamycin (Rapa) toxicity and enables intravenous (IV) therapy in both a xenograft breast cancer model and a murine autoimmune disease model. Rapa has poor solubility, which leads to variable oral bioavailability or drug precipitation following parenteral administration...
2017: Theranostics
https://www.readbyqxmd.com/read/29108974/analysis-of-bacterial-communities-and-characterization-of-antimicrobial-strains-from-cave-microbiota
#2
Muhammad Yasir
In this study for the first-time microbial communities in the caves located in the mountain range of Hindu Kush were evaluated. The samples were analyzed using culture-independent (16S rRNA gene amplicon sequencing) and culture-dependent methods. The amplicon sequencing results revealed a broad taxonomic diversity, including 21 phyla and 20 candidate phyla. Proteobacteria were dominant in both caves, followed by Bacteroidetes, Actinobacteria, Firmicutes, Verrucomicrobia, Planctomycetes, and the archaeal phylum Euryarchaeota...
October 18, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29081433/vernacularizing-the-body-informational-egalitarianism-hindu-divine-design-and-race-in-physiology-schoolbooks-bengal-1859-1877
#3
Projit Bihari Mukharji
Government-aided vernacular schools introduced "human physiology" as a subject in 1859. I use the first couple of schoolbooks and the debate running up to the introduction of the subject to open up the particular and specific histories through which modern anatomo-physiological knowledge was vernacularized in colonial Bengal. In so doing I have two interconnected goals in this article. My first goal is to analyze the precocious decision to teach human physiology to colonial schoolboys, at a time when this was the norm neither in Great Britain nor indeed in traditional Bengali schools...
2017: Bulletin of the History of Medicine
https://www.readbyqxmd.com/read/28970947/ethnic-variations-in-perception-of-human-papillomavirus-and-its-vaccination-among-young-women-in-nepal
#4
Brijesh Sathian, M G Ramesh Babu, Edwin R van Teijlingen, Indrajit Banerjee, Bedanta Roy, Supram Hosuru Subramanya, Elayedath Rajesh, Suresh Devkota
BACKGROUND: The Human Papillomavirus (HPV) is strongly associated with cervical and other cancers. In women, cervical cancer is the third most common cancer. HPV infection can be largely prevented through vaccination of (adolescent) girls. At the same time, Nepal is a low-income country experiencing a cultural change in attitudes towards sex and sexual behaviour. However, in the adolescent population knowledge about HPV, factors associated with an increased risk of HPV and the existence of the vaccination is often low...
March 2017: Nepal journal of epidemiology
https://www.readbyqxmd.com/read/28918753/neonatal-intestinal-obstruction-associated-with-situs-inversus-totalis-two-case-reports-and-a-review-of-the-literature
#5
Rahul Gupta, Varsha Soni, Prakash Devidas Valse, Ram Babu Goyal, Arun Kumar Gupta, Praveen Mathur
BACKGROUND: The association of neonatal intestinal obstruction with situs inversus totalis is extremely rare with only few cases reported in the literature to date. This association poses dilemmas in management. We present two such cases (of Indian origin), and briefly discuss the pertinent literature and measures to prevent unfavorable outcome. CASE PRESENTATION: Case 1: a 1-month-old preterm (1300 g) male neonate belonging to Hindu (Indian) ethnicity presented with recurrent bile-stained vomiting, non-passage of stools and epigastric fullness...
September 18, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28901244/inter-caste-lovers-suicide-pact-case-report-from-nepal
#6
Alok Atreya, Milan Shrestha, Jenash Acharya
Discrimination on cultural and ethnic grounds is a crime in Nepal. [Caste Based Discrimination and Untouchability (Offence and Punishment) Act, 2068 (2011) * * There are two different dates which reflect the Bikram Sambat which is the official Hindu calendar in Nepal. This calendar is 57 years ahead of Gregorian calendar. For example, 19 August 2017 AD is 03 Bhadra 2074 Bikram Sambat. Thus, the date 2068 is in Bikram Sambat, 2011 is per Gregorian calendar which is unofficial so kept in parenthesis. This text is available online from: http://www...
January 1, 2017: Medico-legal Journal
https://www.readbyqxmd.com/read/28880811/the-role-of-religion-in-youth-exposed-to-disasters-in-sri-lanka
#7
Gaithri A Fernando, Dale E Berger
Little research is available on the role of religious coping among youth exposed to disasters. This study examined the role of general and religious coping in a sample of 669 Sri Lankan Buddhist, Hindu, Muslim, and Christian youth (mean age = 14). Youth completed a survey with measures of exposure to disaster-related stressors, psychological and psychosocial functioning, and general and religious coping. Exposure to stressors was the most consistent predictor of negative outcomes, while approach-related coping predicted better outcomes for Buddhist and Hindu youth...
October 2017: Journal of Prevention & Intervention in the Community
https://www.readbyqxmd.com/read/28875394/genomic-based-breeding-tools-for-tropical-maize-improvement
#8
REVIEW
Thammineni Chakradhar, Vemuri Hindu, Palakolanu Sudhakar Reddy
Maize has traditionally been the main staple diet in the Southern Asia and Sub-Saharan Africa and widely grown by millions of resource poor small scale farmers. Approximately, 35.4 million hectares are sown to tropical maize, constituting around 59% of the developing worlds. Tropical maize encounters tremendous challenges besides poor agro-climatic situations with average yields recorded <3 tones/hectare that is far less than the average of developed countries. On the contrary to poor yields, the demand for maize as food, feed, and fuel is continuously increasing in these regions...
December 2017: Genetica
https://www.readbyqxmd.com/read/28836152/effect-of-dietary-supplementation-of-novel-probiotic-bacteria-bacillus-vireti-01-on-antioxidant-defence-system-of-freshwater-prawn-challenged-with-pseudomonas-aeruginosa
#9
S Vidhya Hindu, Natarajan Chandrasekaran, Amitava Mukherjee, John Thomas
The aim of the present work was to isolate probiotic bacteria from the intestinal tract of healthy freshwater prawn Macrobrachium rosenbergii and to examine the effect of the isolated probiotic Bacillus vireti 01 in controlling Pseudomonas aeruginosa infection. This is probably the first report on the isolation of probiotic B. vireti 01 from the intestine of M. rosenbergii. The compounds present in B. vireti 01 were identified using GC-MS analysis. The effect of B. vireti 01-incorporated diet on survival and antioxidant enzymes was studied in M...
August 23, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28832584/losing-its-ground-a-case-study-of-fast-declining-populations-of-a-least-concern-species-the-bonnet-macaque-macaca-radiata
#10
Joseph J Erinjery, Shanthala Kumar, Honnavalli N Kumara, K Mohan, Tejeshwar Dhananjaya, P Sundararaj, Rafi Kent, Mewa Singh
The populations of many species that are widespread and commensal with humans have been drastically declining during the past few decades, but little attention has been paid to their conservation. Here, we report the status of the bonnet macaque, a species that is considered 'least-concern' for conservation. We show that the widely ranging rhesus macaque is expanding its range into the distributional range of the bonnet macaque, a species endemic only to southern India. Bonnet macaques have very low abundance in forests of all types indicating that it is not a typically forest dwelling species...
2017: PloS One
https://www.readbyqxmd.com/read/28831950/post-traumatic-stress-disorder-symptoms-among-children-of-kathmandu-1-year-after-the-2015-earthquake-in-nepal
#11
Shneha Acharya, Dharma Nanda Bhatta, Sawitri Assannangkornchai
OBJECTIVE: The 2015 earthquake in Nepal affected the country in terms of economy, and by causing damage and stress reactions. This study aimed to estimate the prevalence and determine individual child- and family-level predictors of post-traumatic stress disorder (PTSD) symptoms. METHODS: A community-based cross-sectional study was carried out in Kathmandu district 15 months after the earthquake. Multistage cluster sampling was adopted to collect 800 earthquake-affected children aged 7-16 years and a face-to-face interview was conducted...
August 23, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28820672/association-of-religion-and-cultural-tradition-with-alcohol-use-among-some-tribal-communities-of-arunachal-pradesh-india
#12
Himanshu K Chaturvedi, Ram C Bajpai, Preeti Tiwari
Arunachal Pradesh, a land of high mountains and dense forest, is home to many tribal communities, which comprise two thirds of the state's population. Alcohol is one of the common addictive substances used traditionally among them despite much awareness about its harmful effect on health. The present study is focused on finding the association of religion, ethnicity, and demographic characteristics with alcohol use among some tribal communities in Changlang district of Arunachal Pradesh. A cross-sectional household survey was conducted on substance use in Changlang district of Arunachal Pradesh, India...
August 18, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/28817328/lead-content-of-sindoor-a-hindu-religious-powder-and-cosmetic-new-jersey-and-india-2014-2015
#13
Manthan P Shah, Derek G Shendell, Pamela Ohman Strickland, John D Bogden, Francis W Kemp, William Halperin
OBJECTIVES: To assess the extent of lead content of sindoor, a powder used by Hindus for religious and cultural purposes, which has been linked to childhood lead poisoning when inadvertently ingested. METHODS: We purchased 95 samples of sindoor from 66 South Asian stores in New Jersey and 23 samples from India and analyzed samples with atomic absorption spectrophotometry methods for lead. RESULTS: Analysis determined that 79 (83.2%) sindoor samples purchased in the United States and 18 (78...
October 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28814315/incidental-detection-of-two-adult-gravid-filarial-worms-in-breast-a-case-report
#14
Santosh Tummidi, Kanchan Kothari, Roshni Patil, Shruti S Singhal, Pooja Keshan
BACKGROUND: Microfilaria is a major public health problem in tropical and subtropical countries and is an endemic problem in India. Wuchereria bancrofti is the commonest filarial infection. In some lesions, microfilariae and adult filarial worm have been incidentally detected in fine-needle aspirates. CASE PRESENTATION: A 35 year old hindu female presented with lump in upper outer quadrant of left breast. Fine needle aspiration revealed two adult gravid female filarial worms...
August 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28764168/drug-resistance-pattern-in-the-recent-isolates-of-salmonella-typhi-with-special-reference-to-cephalosporins-and-azithromycin-in-the-gangetic-plain
#15
Shesh Raj Patel, Sujit Bharti, Chandra Bhan Pratap, Gopal Nath
INTRODUCTION: Typhoid fever is an endemic disease in India against which many antibiotics are available. In the recent times, emerging resistance to traditional antibiotics, such as Ampicillin, Chloramphenicol and Trimethoprim/sulfamethoxazole, Azithro-mycin and third generation Cephalosporins are being reported and increasingly being used in the treatment of invasive Salmonella infections. However, the latter two drugs have been reported with occasional clinical failures. Currently, we do not have data regarding their drug resistance levels in the recent isolates of Salmonella enterica subspecies enterica serotype Typhi...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28761257/from-hair-in-india-to-hair-india
#16
COMMENT
Ralph M Trüeb
In all cultures, human hair and hairdo have been a powerful metaphor. Tracing back the importance and significance of human hair to the dawn of civilization on the Indian subcontinent, we find that all the Vedic gods are depicted as having uncut hair in mythological stories as well as in legendary pictures. The same is true of the Hindu avatars, and the epic heroes of the Ramayana, and the Mahabharata. Finally, there are a number of hair peculiarities in India pertinent to the creed and religious practices of the Hindu, the Jain, and the Sikh...
January 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/28750370/social-birth-rites-of-passage-for-the-newborn
#17
Michael Obladen
Rites of passage mark important changes during human life and, for the neonate, its transition from intrauterine life into society. Their original intent was to purify the body from blood and meconium. But the cleansing rites had a spiritual dimension from the very start. When the rites of Mesopotamian, Egyptian, Jewish, Greek, Roman, Hindu, Nordic, Muslim, Maya, and Christian cultures are briefly compared, they reveal a remarkable similarity. What most rites had in common was the cleansing of the body, or sprinkling it with water; special clothing; the exorcism of evil spirits; blessings and prayers for good spirits; and a name-giving ceremony and a feast for family, relatives, and friends...
July 28, 2017: Neonatology
https://www.readbyqxmd.com/read/28746003/erich-fromm-s-involvement-with-zen-buddhism-psychoanalysts-and-the-spiritual-quest-in-subsequent-decades
#18
Alan Roland
The first section of this paper covers Erich Fromm's profound involvement with Zen Buddhism, culminating in his co-authoring the book Zen Buddhism and Psychoanalysis in 1960. It details why this was a groundbreaking endeavor, as it countered the pervasive psychoanalytic denigration of spiritual traditions, practices, and experiences. The second section describes the effect of Fromm's Zen Buddhism and Psychoanalysis on the author of this paper, as he came to clinical psychology and psychoanalysis from involvement in Indian philosophy...
August 2017: Psychoanalytic Review
https://www.readbyqxmd.com/read/28733592/machine-learning-model-analysis-of-breeding-habitats-for-the-black-necked-crane-in-central-asian-uplands-under-anthropogenic-pressures
#19
Xuesong Han, Yumin Guo, Chunrong Mi, Falk Huettmann, Lijia Wen
The black-necked crane (Grus nigricollis) is the only alpine crane species and is endemic to the Tibetan Plateau. The breeding habitats of this species are poorly understood, which greatly hampers practical research and conservation work. Using machine learning methods and the best-available data from our 7,000-kilometer mega-transect survey and open access data, we built the first species distribution model (SDM) to analyze the black-necked crane's breeding habitats. Our model showed that current conservation gaps account for 26...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28726477/south-asian-ethnicity-socioeconomic-status-and-psychological-mediators-of-faecal-occult-blood-colorectal-screening-participation-a-prospective-test-of-a-process-model
#20
Sheina Orbell, Ala Szczepura, David Weller, Anil Gumber, Martin S Hagger
OBJECTIVE: Although ethnicity and socioeconomic status (SES) correlate with health inequality, efforts to explain variance in health behavior attributable to these factors are limited by difficulties in population sampling. We used ethnicity identification software to test effects of psychological beliefs about screening as mediators of ethnicity and SES on faecal occult blood colorectal screening behavior in a no-cost health care context. METHOD: Adults aged 50-67 years (N = 1,678), of whom 28% were from minority South Asian religiolinguistic ethnic groups (Hindu-Gujarati/Hindi, Muslim-Urdu and Sikh-Punjabi), participated in a prospective survey study...
July 20, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
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