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https://www.readbyqxmd.com/read/29046023/-determination-of-a-new-cow-s-milk-based-formula-allergenic-capacity-in-7-infants
#1
Beatriz Estella López-Marín, Benjamín Rojano, Luz Marina Carvajal-de Pabón
BACKGROUND: Cow's milk protein allergy is the main allergic problem during the first year of life, possibly owing to immune and gastrointestinal systems poor maturation. To prevent allergic reactions, the content and type of proteins in infant formulas resemble those of breast milk. We believe that reactions are due rather to the amount than to the type of protein. OBJECTIVE: To design a new formula with cow's milk that provides the infant with the main nutrients at an affordable cost and with lower risk for the development of allergies...
July 2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/29045978/-clinicopathologic-features-of-infant-dysembryoplastic-neuroepithelial-tumor-a-case-report-and-literature-review
#2
H Wang, J T Ye, H X Yao, D Li, Y Dong
Dysembryoplastic neuroepithelial tumor (DNT) has traditionally been viewed as rare benign tumors that present with seizure widely considered curable with surgery alone. Most DNTs occur in childhood and young adults. However, rare reported cases occur in infants. This paper reported an infant case of DNT and its diagnosis, differential diagnosis, treatment, molecular features and prognosis based on the review of current literatures. The age onset of this patient was only 11 months old. The clinical manifestations were partial seizures and the imaging data untypical; CT and MRI were all supportive of astrocytoma...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045974/-echocardiographic-diagnosis-of-infracardiac-total-anomalous-pulmonary-venous-connection
#3
S T Ren, Y Wang, J H Zhou, J Long, C H Wang, D B Li, Y Z Huang
OBJECTIVE: To investigate the clinical usefulness of echocardiography in the diagnosis of infracardiac total anomalous pulmonary venous connection (ITAPVC) in neonates and infants. METHODS: Retrospective analysis on 8 patients with ITAPVC was performed using echocardiography between April 2006 and December 2016. There were 4 boys and 4 girls with a mean age of 79.8 days (ranging from 15 to 195 days). A combined scanning via parasternal, subcostal and apical acoustic windows had been employed to diagnose ITAPVC and to trace the course and site of the anomalous pulmonary venous drainage, and to confirm the direction of the inter-atrial shunt and enlargement of right atrium and right ventricle...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045957/-clinical-characteristics-of-neonatal-fungal-sepsis-in-neonatal-intensive-care-unit
#4
X Zhang, X F Ru, Y Wang, X Li, T Sang, Q Feng
OBJECTIVE: To study the characteristics of neonatal fungal sepsis and the difference between bacterial sepsis and fungal sepsis. To improve the understanding of neonatal fungal sepsis. METHODS: Clinical data of neonatal fungal sepsis in neonatal intensive care unit (NICU) were collected from 2011 to 2016 in Peking University first Hospital. The clinical characteristics were analyzed retrospectively. The difference between neonatal fungal sepsis and bacterial sepsis was also analyzed...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045765/oral-anti-diabetic-agents-for-women-with-established-diabetes-impaired-glucose-tolerance-or-previous-gestational-diabetes-planning-pregnancy-or-pregnant-women-with-pre-existing-diabetes
#5
REVIEW
Joanna Tieu, Suzette Coat, William Hague, Philippa Middleton, Emily Shepherd
BACKGROUND: While most guidance recommends the use of insulin in women whose pregnancies are affected by pre-existing diabetes, oral anti-diabetic agents may be more acceptable to women. The effects of these oral anti-diabetic agents on maternal and infant health outcomes need to be established in pregnant women with pre-existing diabetes or impaired glucose tolerance, as well as in women with previous gestational diabetes mellitus preconceptionally or during a subsequent pregnancy. OBJECTIVES: To investigate the effects of oral anti-diabetic agents in women with established diabetes, impaired glucose tolerance or previous gestational diabetes who are planning a pregnancy, or pregnant women with pre-existing diabetes, on maternal and infant health...
October 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29045741/respiratory-syncytial-virus-genotypes-host-immune-profiles-and-disease-severity-in-young-children-hospitalized-with-bronchiolitis
#6
Rosa Rodriguez-Fernandez, Lorena I Tapia, Chin-Fen Yang, Juan Pablo Torres, Susana Chavez-Bueno, Carla Garcia, Lisa M Jaramillo, Melissa Moore-Clingenpeel, Hasan S Jafri, Mark E Peeples, Pedro A Piedra, Octavio Ramilo, Asuncion Mejias
Background: Data on how RSV genotypes influence disease severity and host immune responses is limited. We characterized the genetic variability of RSV during five seasons, and evaluated the role of RSV subtypes, genotypes and viral loads on disease severity and host transcriptional profiles. Methods: Prospective, observational study including a convenience sample of healthy infants hospitalized with RSV bronchiolitis. Nasopharyngeal samples for viral load quantitation, typing and genotyping, and blood samples for transcriptome analyses were obtained within 24h of hospitalization...
October 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29045739/assessment-of-ketamine-binding-of-the-serotonin-transporter-in-humans-with-positron-emission-tomography
#7
Marie Spies, Gregory M James, Neydher Berroterán-Infante, Harald Ibeschitz, Georg S Kranz, Jakob Unterholzner, Mathis Godbersen, Gregor Gryglewski, Marius Hienert, Johannes Jungwirth, Verena Pichler, Birgit Reiter, Leo Silberbauer, Dietmar Winkler, Markus Mitterhauser, Thomas Stimpfl, Marcus Hacker, Siegfried Kasper, Rupert Lanzenberger
Background: Comprehensive description of ketamine's molecular binding profile becomes increasingly pressing as use in real life patient cohorts widens. Animal studies attribute a significant role in the substance's antidepressant effects to the serotoninergic system. The serotonin transporter (SERT) is a highly relevant target in this context because it is central to depressive pathophysiology and treatment. This is to our knowledge the first study investigating ketamine's SERT binding in-vivo in humans...
October 16, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29045697/impact-of-human-immunodeficiency-virus-drug-resistance-on-treatment-of-human-immunodeficiency-virus-infection-in-children-in-low-and-middle-income-countries
#8
George K Siberry, Anouk Amzel, Artur Ramos, Emilia D Rivadeneira
Children living with human immunodeficiency virus (HIV) in low- and middle-income countries (LMICs) experience higher rates of virologic failure than adults. Human immunodeficiency virus drug resistance (HIVDR) plays a major role in pediatric HIV treatment failure because nonsuppressive maternal antiretroviral therapy (ART) during pregnancy and breastfeeding as well as infant antiretroviral prophylaxis lead to high rates of pretreatment drug resistance to regimens most commonly used in children living with HIV...
October 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29045693/pharmacokinetics-of-ceftaroline-in-a-preterm-infant-with-methicillin-resistant-staphylococcus-aureus-pneumonia
#9
Sara N Salerno, Janice Bernhardt, Matthew Laughon, Ravi Jhaveri, Matthew Massaro, Daniel Gonzalez
We report here the first pharmacokinetic-pharmacodynamic relationship for ceftaroline in a preterm infant born at <28 weeks' gestational age who was given ceftaroline (8.5 mg/kg every 8 hours) for pneumonia attributable to methicillin-resistant Staphyloccocus aureus. This dose of ceftaroline was adequate to achieve the pharmacodynamic endpoint associated with efficacy for methicillin-resistant Staphyloccocus aureus.
October 16, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29045690/clinical-characteristics-of-hospitalized-infants-with-laboratory-confirmed-pertussis-in-guatemala
#10
Varun K Phadke, John P McCracken, Jennifer L Kriss, Maria R Lopez, Kim A Lindblade, Joe P Bryan, Miguel E Garcia, Carlos E Funes, Saad B Omer
Background: Pertussis is an important cause of hospitalization and death in infants too young to be vaccinated (aged <2 months). Limited data on infant pertussis have been reported from Central America. The aim of this study was to characterize acute respiratory illnesses (ARIs) attributable to Bordetella pertussis among infants enrolled in an ongoing surveillance study in Guatemala. Methods: As part of a population-based surveillance study in Guatemala, infants aged <2 months who presented with ARI and required hospitalization were enrolled, and nasopharyngeal and oropharyngeal swab specimens were obtained...
October 13, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29045653/a-quality-improvement-project-to-reduce-hypothermia-in-preterm-infants-on-admission-to-the-neonatal-intensive-care-unit
#11
Wai Yan Yip, Bin Huey Quek, Mary Choi Wan Fong, Thilagamangai, Sally Siew Gim Ong, Bee Leong Lim, Bo Chu Lo, Pratibha Agarwal
Objective: To study effectiveness of quality improvement interventions in reducing hypothermia in preterm infants on admission to neonatal intensive care unit. Design: Quality improvement methodologies including multidisciplinary planning and implementation of evidence-based interventions. Data during and post-implementation were collected. Setting and participants: In total, 84 preterm infants with birth weights ≤ 1500 g delivered during implementation period (October 2008-April 2009) were compared with 168 historical controls and 947 infants in the subsequent 4 years...
October 17, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29045606/clinical-and-laboratory-features-of-group-b-streptococcus-meningitis-in-infants-and-newborns-study-of-848-cases-in-france-from-2001-2014
#12
Anne-Sophie Romain, Robert Cohen, Céline Plainvert, Caroline Joubrel, Stéphane Béchet, Amélie Perret, Asmaa Tazi, Claire Poyart, Corinne Levy
Background: Group B Streptococcus (GBS) disease is the leading cause of neonatal bacterial meningitis despite women receiving an intravenous antibiotic prophylaxis (IAP) during labor. We aimed to describe GBS meningitis in children less than 1 year old in France during 2001-2014. Methods: Clinical and biological data of GBS meningitis gathered by ACTIV/GPIP and the French National Reference Center for Streptococci were analyzed. The cases were classified by age: 0 to 6 days old (early-onset disease [EOD]), newborns and infants 7 to 89 days old (late-onset disease [LOD]: LOD1, 7-26 days; LOD2, 27-89 days to 3 months) and infants 3 months to 1 year old (infant disease [ID])...
October 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29045402/triadic-male-infant-male-interaction-serves-in-bond-maintenance-in-male-assamese-macaques
#13
Josefine Kalbitz, Oliver Schülke, Julia Ostner
While the ultimate consequences of social bonds start to be better understood, the proximate behavioural mechanisms underlying the formation and maintenance of these close affiliative relationships have received less attention. We investigated the possible function of male-infant-male interactions (MIMIs) in male-male social bonding processes by analysing about 9000h of focal animal observations collected on two groups of wild Assamese macaques. In support of an agonistic buffering function of MIMIs, after engaging in a MIMI upon approach, subordinates stayed longer in close proximity of a dominant male...
2017: PloS One
https://www.readbyqxmd.com/read/29045354/the-case-for-thoughtful-prescribing-of-ppis-in-infants
#14
Rachel L Rosen, Usha Krishnan, Hayat Mousa, Luigi Dall'oglio, Christophe Faure, Frederic Gottrand
No abstract text is available yet for this article.
October 17, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29045351/awareness-and-implementation-of-the-2014%C3%A2-espghan-naspghan-guideline-for-childhood-functional-constipation
#15
Ilan J N Koppen, M H Vriesman, M M Tabbers, C Di Lorenzo, M A Benninga
OBJECTIVE: To assess if physicians approach children with functional constipation according to the 2014 ESPGHAN/NASPGHAN guideline. METHODS: We invited pediatricians and pediatric gastroenterologists in the Netherlands and the U.S. to participate in this anonymous survey using a self-developed questionnaire containing 19 multiple-choice questions concerning evaluation and treatment of children with constipation. RESULTS: We included 328 physicians (67% from the U...
October 17, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29045350/donor-human-milk-and-fortifier-use-in-united-states-level-2-3-and-4-neonatal-care-hospitals
#16
Maryanne Tigchelaar Perrin
OBJECTIVE: In 2011 the United States Surgeon General issued a call to action to "identify and address obstacles to greater availability of safe banked donor milk for fragile infants." The purpose of this study is to analyze patterns in donor human milk (DHM) and fortifier use in level 2, 3, and 4 neonatal facilities in 2015 and to identify factors associated with non-use. METHODS: Data from the 2015 Maternity Practices in Infant Nutrition and Care survey, conducted by the Center for Disease Control and Prevention, was analyzed for questions about feeding practices within neonatal hospitals...
October 17, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29045258/early-behavioral-risks-of-childhood-and-adolescent-daytime-urinary-incontinence-and-nocturnal-enuresis
#17
Monica M A Vasconcelos, Patricia East, Estela Blanco, Emily S Lukacz, Gabriela Caballero, Betsy Lozoff, Sheila Gahagan
OBJECTIVE: To investigate whether infant temperament and childhood internalizing, externalizing, and inattention symptoms increase the likelihood of daytime urinary incontinence or nocturnal enuresis at 10 years and adolescence (11.9-17.8 years). METHOD: Data were from a longitudinal cohort of 1119 healthy Chilean children. We assessed behavioral symptoms at infancy, 5 years, and 10 years and their relationship with subsequent daytime urinary incontinence and nocturnal enuresis...
October 17, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29045257/fathers-the-lost-ring-in-the-chain-of-family-centered-care-a-phenomenological-study-in-neonatal-intensive-care-units-of-iran
#18
Sousan Valizadeh, Jila Mirlashari, Elham Navab, Wendy Higman, Fatemeh Ghorbani
BACKGROUND: The basic principles of family-centered care in neonatal intensive care unit (NICU) include the unlimited presence of parents and their participation in infant's care. Nurses play a central role in encouraging parental attachment with their infant. PURPOSE: This study was carried out with the aim of understanding NICU nurses' lived experiences of family participation in family-centered care. METHODS: This interpretative phenomenological study was conducted on the basis of Heideggerian philosophy...
October 17, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29045256/a-quality-improvement-initiative-to-increase-scoring-consistency-and-accuracy-of-the-finnegan-tool-challenges-in-obtaining-reliable-assessments-of-drug-withdrawal-in-neonatal-abstinence-syndrome
#19
Wendy Timpson, Cheryl Killoran, Louise Maranda, Alan Picarillo, Elisabeth Bloch-Salisbury
BACKGROUND: Current practice for diagnosing neonatal abstinence syndrome and guiding pharmacological management of neonatal drug withdrawal is dependent on nursing assessments and repeated evaluation of clinical signs. PURPOSE: This single-center quality improvement initiative was designed to improve accuracy and consistency of Finnegan scores among neonatal nurses. METHODS: One-hundred seventy neonatal nurses participated in a single-session withdrawal-assessment program that incorporated education, scoring guidelines, and a restructured Finnegan scale...
October 17, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29045255/listening-to-relaxing-music-improves-physiological-responses-in-premature-infants-a-randomized-controlled-trial
#20
Rafael A Caparros-Gonzalez, Alejandro de la Torre-Luque, Carolina Diaz-Piedra, Francisco J Vico, Gualberto Buela-Casal
BACKGROUND: Premature infants are exposed to high levels of noise in the neonatal intensive care unit (NICU). PURPOSE: This study evaluated the effect of a relaxing music therapy intervention composed by artificial intelligence on respiratory rate, systolic and diastolic blood pressure, and heart rate. METHODS: A double-blind, randomized, controlled trial was conducted in the NICUs of 2 general public hospitals in Andalusia, Spain. Participants were 17 healthy premature infants, randomly allocated to the intervention group or the control group (silence) at a 1:1 ratio...
October 17, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
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