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https://www.readbyqxmd.com/read/29776939/outcomes-of-transanal-endorectal-pull-through-for-rectal-atresia
#1
Mutaz Gieballa, Nawaf AlKharashi, Mohammed Al-Namshan, Saud AlJadaan
Rectal atresia is a rare anorectal malformation, and it has been reported to represent 1%-2% of all anorectal malformations. We report three newborns who were admitted to the neonatal intensive care unit for abdominal distention, bilious vomiting and failure to pass meconium. The external anus and genitalia were normal and well formed. Digital rectal examination showed a blind-ending anal canal. All three infants were initially managed with diverting colostomy and then transanal resection of the rectal atresia with primary anastomosis, followed by colostomy closure...
May 18, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29764391/practice-and-outcomes-of-neonatal-resuscitation-for-newborns-with-birth-asphyxia-at-kakamega-county-general-hospital-kenya-a-direct-observation-study
#2
Duncan N Shikuku, Benson Milimo, Elizabeth Ayebare, Peter Gisore, Gorrette Nalwadda
BACKGROUND: About three - quarters of all neonatal deaths occur during the first week of life, with over half of these occurring within the first 24 h after birth. The first minutes after birth are critical to reducing neonatal mortality. Successful neonatal resuscitation (NR) has the potential to prevent these perinatal mortalities related to birth asphyxia. This study described the practice of NR and outcomes of newborns with birth asphyxia in a busy referral hospital. METHODS: Direct observations of 138 NRs by 28 healthcare providers (HCPs) were conducted using a predetermined checklist adapted from the national pediatric resuscitation protocol...
May 15, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29760169/dysbiosis-of-maternal-and-neonatal-microbiota-associated-with-gestational-diabetes-mellitus
#3
Jinfeng Wang, Jiayong Zheng, Wenyu Shi, Nan Du, Xiaomin Xu, Yanming Zhang, Peifeng Ji, Fengyi Zhang, Zhen Jia, Yeping Wang, Zhi Zheng, Hongping Zhang, Fangqing Zhao
OBJECTIVE: The initial colonisation of the human microbiota and the impact of maternal health on neonatal microbiota at birth remain largely unknown. The aim of our study is to investigate the possible dysbiosis of maternal and neonatal microbiota associated with gestational diabetes mellitus (GDM) and to estimate the potential risks of the microbial shift to neonates. DESIGN: Pregnant women and neonates suffering from GDM were enrolled and 581 maternal (oral, intestinal and vaginal) and 248 neonatal (oral, pharyngeal, meconium and amniotic fluid) samples were collected...
May 14, 2018: Gut
https://www.readbyqxmd.com/read/29755962/acceptability-of-bedside-resuscitation-with-intact-umbilical-cord-to-clinicians-and-patients-families-in-the-united-states
#4
Anup C Katheria, Samuel R Sorkhi, Kasim Hassen, Arij Faksh, Zahra Ghorishi, Debra Poeltler
Background: While delayed umbilical cord clamping in preterm infants has shown to improve long-term neurological outcomes, infants who are thought to need resuscitation do not receive delayed cord clamping even though they may benefit the most. A mobile resuscitation platform allows infants to be resuscitated at the mother's bedside with the cord intact. The newborn is supplied with placental blood during the resuscitation in view of the mother. The objective of the study is to assess the usability and acceptability of mobile resuscitation platform, LifeStart trolley, among the infants' parents and perinatal providers...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29751786/meconium-peritonitis-due-to-fetal-appendiceal-perforation-two-case-reports-and-a-brief-review-of-the-literature
#5
Yi Wang, Yeming Wu, Wenbin Guan, Wenbo Yan, Yuhua Li, Jin Fang, Jun Wang
BACKGROUND: Meconium peritonitis is an infrequent congenital disease usually caused by perforation of the fetal digestive tract. Meconium peritonitis resulting from intrauterine appendiceal perforation has been rarely reported and is often overlooked during pregnancy. We herein report two cases of fetal appendiceal perforation. CASE PRESENTATION: Two neonates were found to have intestinal distension and gradually increasing ascites antenatally. After birth, diagnostic abdominal punctures revealed meconium peritonitis...
May 11, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29750290/neonatal-intestinal-obstruction-syndrome
#6
Manuel Gil Vargas, Mariana L Miguel-Sardaneta, Michelle Rosas-Téllez, Dayana Pereira-Reyes, Jaime M Justo-Janeiro
Neonatal intestinal obstruction is caused by an anatomical abnormality that produces bowel movement failure. Intestinal obstruction presents with three classic clinical signs: vomiting, abdominal distention, and failure to pass meconium. Intestinal obstruction is one of the most common causes for admitting a pediatric patient to the pediatric surgery unit in his or her first weeks of postnatal life. Congenital obstruction of the digestive tract in neonates is a common problem, with the most frequent cause being anorectal malformations (41%), followed by esophageal obstruction (24%), and duodenal obstruction (20%)...
May 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29709845/vitelline-fistula-associated-with-omphalocele-diagnostic-dilemma
#7
Edgar D Sy, Yen-Shen Shan, Chyi-Her Lin
INTRODUCTION: Combination vitelline fistula (VF) and omphalocele at birth is a rare congenital anomaly as a result disturbance in organogenesis with failure of normal return of intestines into the abdominal cavity and failed obliteration of the vitelline duct. CASE PRESENTATION: A newborn presented with omphalocele sac with visible intestine, stoma like lesion with prolapsing mucosa just lateral to the umbilical cord and passage of meconium stool. Operative surgery was confirmed an intact omphalocele sac and vitelline fistula...
April 16, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29709288/is-the-bishop-koop-procedure-useful-in-severe-jejunoileal-atresia
#8
Yanfen Peng, Haiqing Zheng, Qiuming He, Zhe Wang, Hong Zhang, Puja Bk Chaudhari, Wei Zhong, Jiakang Yu
PURPOSE: The aim of this study was to report our experience using the Bishop-Koop procedure for the treatment of various surgical problems of jejunoileal atresia including luminal discrepancy, complex meconium peritonitis, type IIIb and type IV atresia which we defined as severe jejunoileal atresia. METHODS: This retrospective study was performed on the patients with severe jejunoileal atresia who underwent Bishop-Koop procedure at a tertiary center in China over a five year of period...
April 5, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29701148/quantification-of-methamphetamine-%C3%A2-shabu%C3%A2-in-biological-matrices-to-detect-prenatal-exposure-a-case-report-and-a-literature-review
#9
Pilar Jarque, Antonia Roca, Isabel Gomila, Valeria Noce, B Bernardino Barcelo, Julia Klein
BACKGROUND: Methamphetamine misuse represents an increasing global public health problem. Its consumption during pregnancy becomes a relevant issue, since it has clinical consequences for the child's health and the pregnant woman. Despite this, there are only few data in the literature that include analytical results in the matrices used to detect prenatal exposure. OBJECTIVES: 1) Present a case report of prenatal methamphetamine exposure with toxicological analytical confirmation in biological matrices; and 2) Perform a compilation of prenatal methamphetamine exposure studies and case reports which include toxicological analytical results...
April 26, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29695022/catheter-related-arterial-thrombosis-in-neonates-and-children-a-systematic-review
#10
Mattia Rizzi, Neil Goldenberg, Mariana Bonduel, Shoshana Revel-Vilk, Ernest Amankwah, Manuela Albisetti
Catheter-related arterial thrombosis (CAT) is increasingly recognized in children. Available data are scarce and based on expert opinions. This systematic review aimed to identify knowledge on paediatric CAT. Among 3,484 publications, 22 met inclusion criteria. Fourteen reported on CAT due to umbilical arterial catheter (UAC), two to extremity indwelling catheter (EIC), one to both and five to cardiac catheter (CC). The overall cumulative incidence of CAT was 21% (95% confidence interval [CI], 13-31) with a relative incidence of 20% (95% CI, 10-33) for UAC and 11% (95% CI, 3-21) for CC-related CAT...
April 25, 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29692998/early-diagnosis-from-newborn-screening-maximises-survival-in-severe-cystic-fibrosis
#11
Gloria Tridello, Carlo Castellani, Ilaria Meneghelli, Anna Tamanini, Baroukh M Assael
Newborn screening (NBS) for cystic fibrosis (CF) has been gradually established in several countries, but scant data are available on its long-term effects on survival. Our objective was to evaluate the long-term effects of CF NBS on survival. 586 patients, diagnosed and followed between 1971 and 2014 at the Verona CF Centre were analysed. Eligibility was confirmed in 342 cases diagnosed by NBS, 101 with meconium ileus and 143 through symptoms (44 out of 143 were NBS false negatives). The primary end-point was the 30-year overall survival in patients diagnosed by NBS...
April 2018: ERJ Open Research
https://www.readbyqxmd.com/read/29690730/-a-clinical-retrospective-study-on-160-cases-of-multiple-umbilical-cord-around-the-neck
#12
Y Q Zhang, W Zhao, K T Chu, Y Zhao, L P Chen, Y Yu, X J Han
Objective: To compare the neonatal and maternal outcomes between the patients with umbilical cord around the neck (≥3 loops) and with (1 or 2 loops). Methods: A retrospective analysis was conducted on the clinical data of 160 cases with multiple umbilical cord around the neck (≥3 loops) in the Department of Obstetrics, Women's Hospital School of Medicine Zhejiang University between January 2014 and April 2017.For each case, two control women who gave birth at the same day with vertex position and singletons were selected...
April 17, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29687488/risk-factors-for-nonreassuring-fetal-heart-rate-tracings-after-artificial-rupture-of-membranes-in-spontaneous-labor
#13
Hadas Ganer Herman, Liliya Tamayev, Rotem Houli, Hadas Miremberg, Jacob Bar, Michal Kovo
BACKGROUND: We aimed to characterize factors associated with nonreassuring fetal heart (FHR) tracings after artificial rupture of membranes (AROM), during the active phase of labor. METHODS: Delivery charts of patients who presented in spontaneous labor, at term, between 2015 and 2016 were reviewed. We identified cases in which AROM was performed during the active stage of labor. We compared deliveries with a normal FHR and those who developed nonreassuring FHR...
April 24, 2018: Birth
https://www.readbyqxmd.com/read/29684443/modified-porcine-surfactant-enriched-by-recombinant-human-superoxide-dismutase-for-experimental-meconium-aspiration-syndrome
#14
Jana Kopincova, Pavol Mikolka, Maros Kolomaznik, Petra Kosutova, Andrea Calkovska, Daniela Mokra
AIMS: Combination of exogenous surfactant with antioxidant enzyme recombinant human superoxide dismutase (rhSOD) was tested in the treatment of experimental meconium aspiration syndrome as oxidative processes play key role in its pathogenesis. MATERIAL AND METHODS: Young New Zealand rabbits were instilled by saline (Sal group) or by meconium suspension (Mec group). Some of meconium-instilled animals were treated by surfactant alone (Surf group) or surfactant in combination with rhSOD (Surf + SOD group) and oxygen-ventilated for 5 h...
April 20, 2018: Life Sciences
https://www.readbyqxmd.com/read/29681705/cloacal-malformation-variant-in-a-male-neonate
#15
Rahul Gupta, Pramila Sharma, Arvind Kumar Shukla, Manisha Goyal, Ashok Gupta
Cloacal malformation is a rare entity and is invariably referred only to females. We are reporting a very rare case of cloacal malformation variant in a 6-day-old male neonate who presented with absent anal opening along with passage of urine and meconium from an abnormal opening in the perineum.
April 2018: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/29662276/comparison-between-use-of-oral-misoprostol-versus-vaginal-misoprostol-for-induction-of-labour-at-term
#16
Prameela, Kavya D Sharma
Background and Objective: In modern obstetrics, around 30% of cases require induction of labour for various reasons. Misoprostol is gaining popularity as pharmacological inducing agent, though the route and dosage of administration are not standardised. The objective of the study is to compare the safety and efficacy of the two routes of misoprostol administration-oral (100 μg 4th hourly) and vaginal (25 μg 4th hourly), for induction of labour at term. Methods: In this randomised trial, 104 women having crossed the expected date of delivery without going into spontaneous labour and cases which had premature rupture of membranes <12 h were considered for labour induction and were divided into two equal groups...
April 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29629694/effect-of-gastric-lavage-on-meconium-aspiration-syndrome-and-feed-intolerance-in-vigorous-infants-born-with-meconium-stained-amniotic-fluid-a-randomized-control-trial
#17
RANDOMIZED CONTROLLED TRIAL
Shrishail Gidaganti, M M A Faridi, Manish Narang, Prerna Batra
OBJECTIVE: To compare the incidence of meconium aspiration syndrome and feed intolerance in infants born through meconium stained amniotic fluid with or without gastric lavage performed at birth. SETTING: Neonatal unit of a teaching hospital in New Delhi, India. DESIGN: Parallel group unmasked randomized controlled trial. PARTICIPANTS: 700 vigorous infants of gestational age ≥34 weeks from through meconium stained amniotic fluid...
March 15, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29625807/-meconium-periorchitis-in-the-diagnosis-of-scrotal-mass
#18
Miriam García González, Isabel Casal Beloy, Lara Martínez González, Teresa Dargallo Carbonell
No abstract text is available yet for this article.
April 3, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29621962/maternal-hair-and-neonatal-meconium-to-assess-gestational-consumption-and-prenatal-exposure-to-drugs-of-abuse-and-psychoactive-drugs
#19
Francesco Paolo Busardo, Laura Almeida, Laura Cortes, Sally Sabraa, Marta Muniesaa, Oscar Garcia-Algara, Maria Dolores Gomez-Roiga
BACKGROUND: In the last two decades, the consumption of drugs of abuse among women of childbearing age has experienced a significant increase and results from analyses of surveys concerning maternal intake of psychoactive prescription drugs during pregnancy indicate that the rates of intake are increasing each year. Analyses of biological matrices such as maternal hair and neonatal meconium have recently been used for assessment of gestational consumption and consequent prenatal exposure to drugs of abuse in high-risk groups of women METHODS: Maternal hair and neonatal meconium were analyzed by validated chromatographic mass spectrometric methodologies to disclose gestational use of drugs of abuse and psychoactive prescription drugs and consequent prenatal exposure in a cohort of 513 mother-newborn dyads at the Sant Joan de Déu Barcelona Hospital, Spain, during 2012- 2013...
April 5, 2018: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/29614446/intrapartum-and-perinatal-results-associated-with-different-degrees-of-staining-of-meconium-stained-amniotic-fluid
#20
Vanesa Rodríguez Fernández, Carlos Nicolás López Ramón Y Cajal, Elena Marín Ortiz, Emilio Couceiro Naveira
OBJECTIVE: To determine the intrapartum and perinatal results associated with different degrees of staining of meconium stained amniotic fluid (MSAF). STUDY DESIGN: In a retrospective cohort study of all singleton deliveries over a period of one year (2015) in a tertiary hospital, we compared different degrees of MSAF (yellow, green and thick) to clear amniotic fluids, and analysed in each group maternal, intrapartum and neonatal variables as well as umbilical cord blood gas analysis...
May 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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