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https://www.readbyqxmd.com/read/28447335/positive-alcohol-expectancies-mediate-associations-between-adhd-behaviors-and-alcohol-related-problems-among-college-students
#1
Alexis Elmore, Molly Nikolas, Will Canu
An increasing percentage of college students report being affected by ADHD behaviors, and this population is at increased risk of experiencing negative consequences associated with alcohol consumption. However, specific factors motivating alcohol consumption and contributing to negative outcomes among these individuals are not well understood. Recent work suggests alcohol expectancies may interact with ADHD behaviors to influence negative drinking-related outcomes among those with elevated inattention and/or hyperactivity-impulsivity...
April 26, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/28442359/emg-biofeedback-training-in-adult-attention-deficit-hyperactivity-disorder-an-active-control-training
#2
Beatrix Barth, Kerstin Mayer, Ute Strehl, Andreas J Fallgatter, Ann-Christine Ehlis
OBJECTIVE: The present study aimed at revealing neurophysiological effects induced by electromyography (EMG) based biofeedback, considered as a semi-active control condition in neurofeedback studies, in adult attention-deficit/hyperactivity disorder (ADHD) patients. METHODS: 20 adult ADHD patients trained their muscle activity in the left and right supraspinatus muscle over the course of 30 EMG biofeedback sessions. Changes induced by the EMG feedback were evaluated at a clinical and neurophysiological level; additionally, the relation between changes in EEG activity recorded at the vertex over the training course and changes of symptom severity over the treatment course were assessed in order to investigate the mechanisms underlying clinical effects of EMG biofeedback...
April 22, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28437666/attentional-control-of-emotional-interference-in-children-with-adhd-and-typically-developing-children-an-emotional-n-back-study
#3
Thomas Villemonteix, Ivo Marx, Mathilde Septier, Christoph Berger, Thomas Hacker, Sara Bahadori, Eric Acquaviva, Isabelle Massat
Emotional interference control refers to the ability to remain focused on goal-oriented processes when confronted with disrupting but irrelevant emotional stimuli, a process that may be impaired in children and adults with attention deficit/hyperactivity disorder (ADHD). However, emotional interference levels are known to be associated with trait anxiety, and patients with ADHD often display elevated levels of trait anxiety, such as these may have confounded previous findings of decreased emotional interference control in this population...
April 18, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28432778/cross-species-studies-of-cognition-relevant-to-drug-discovery-a-translational-approach
#4
REVIEW
T W Robbins
This Review advances the case that bidirectional, cross-species translation of findings from experimental animals to and from humans is an important strategy for drug discovery. Animal models of mental disorders require appropriate behavioural or cognitive outcome variables that can be generalized cross-species. One example is the treatment of impulsive behaviour in attention deficit hyperactivity disorder (ADHD) with stimulant drugs. Performance on the stop signal reaction task as an index of impulsivity is improved both in healthy human volunteers and in patients with adult ADHD by stimulant drugs and also by the selective noradrenergic reuptake blocker atomoxetine...
April 22, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28429134/systematic-review-of-quality-of-life-and-functional-outcomes-in-randomized-placebo-controlled-studies-of-medications-for-attention-deficit-hyperactivity-disorder
#5
REVIEW
David R Coghill, Tobias Banaschewski, César Soutullo, Matthew G Cottingham, Alessandro Zuddas
Children, adolescents and adults with attention-deficit/hyperactivity disorder (ADHD) experience functional impairment and poor health-related quality of life (HRQoL) in addition to symptoms of inattention/hyperactivity-impulsivity. To synthesize qualitatively the published evidence from randomized, double-blind, placebo-controlled trials of the effectiveness of pharmacotherapy on functional impairment or HRQoL in patients with ADHD, a systematic PubMed searching and screening strategy was designed to identify journal articles meeting pre-specified criteria...
April 20, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28428763/adhd-lifestyles-and-comorbidities-a-call-for-an-holistic-perspective-from-medical-to-societal-intervening-factors
#6
REVIEW
Simon Weissenberger, Radek Ptacek, Martina Klicperova-Baker, Andreja Erman, Katerina Schonova, Jiri Raboch, Michal Goetz
The review examines Attention Deficit Hyperactivity Disorder (ADHD in its Child and Adult form) and its various presentations (Hyperactive Impulsive, Inattentive, and Combined) with a particular focus on environmental (incl. social factors), lifestyles and comorbidities. It is argued that ADHD is best understood in a holistic and interactive context and a vast empirical literature is presented to illustrate the point: Environmental factors include stress in general as well as exposure to toxins (phthalates, bisphenol A)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28421383/pharmacokinetics-safety-and-tolerability-of-single-and-multiple-doses-of-guanfacine-extended-release-formulation-in-healthy-japanese-and-caucasian-male-adults
#7
Yumiko Matsuo, Masafumi Okita, James Ermer, Toshihiro Wajima
BACKGROUND AND OBJECTIVE: Guanfacine extended-release (guanfacine XR) could be a useful treatment option for children and adolescent patients with attention-deficit/hyperactivity disorder (ADHD). As an initial step in the development in Japan, the pharmacokinetics, safety and tolerability were assessed in healthy Japanese and non-Hispanic Caucasian adults. METHODS: A Phase 1, double-blind, randomized, placebo-controlled, single- and multiple-oral dose escalation study of guanfacine XR was conducted...
April 18, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/28414486/girls-with-childhood-adhd-as-adults-cross-domain-outcomes-by-diagnostic-persistence
#8
Elizabeth B Owens, Christine Zalecki, Peter Gillette, Stephen P Hinshaw
OBJECTIVE: To ascertain adult outcomes in 10 domains reflecting symptomatology (internalizing, externalizing, self-injury, substance use), attainment (education, employment), and impairment (health, social, driving, overall) as a function of both childhood diagnosis of attention-deficit/hyperactivity disorder (ADHD) and persistence of ADHD symptoms across time. METHOD: We prospectively followed 140 grade-school-aged girls with rigorously diagnosed childhood ADHD and 88 age- and ethnicity-matched comparison girls for 16 years...
April 17, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28413936/processing-speed-can-monitor-stimulant-medication-effects-in-adults-with-attention-deficit-disorder-with-hyperactivity
#9
Niels Peter Nielsen, Elisabeth H Wiig, Svante Bäck, Jan Gustafsson
BACKGROUND: Treatment responses to methylphenidate by adults with ADHD are generally monitored against DSM-IV/DSM-V symptomatology, rating scales or interviews during reviews. AIMS: To evaluate the use of single- and dual-dimension processing-speed and efficiency measures to monitor the effects of pharmacological treatment with methylphenidate after a short period off medication. METHODS: A Quick Test of Cognitive Speed (AQT) monitored the effects of immediate-release methylphenidate in 40 previously diagnosed and medicated adults with ADHD...
May 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28413925/triple-bead-mixed-amphetamine-salts-shp465-in-adults-with-adhd-results-of-a-phase-3-double-blind-randomized-forced-dose-trial
#10
Glen Frick, Brian Yan, Lenard A Adler
OBJECTIVE: Evaluate the efficacy and tolerability of triple-bead mixed amphetamine salts (MAS) in ADHD. METHOD: Adults with ADHD Rating Scale IV (ADHD-RS-IV) total scores ≥32 were randomized to 6 weeks of triple-bead MAS (25, 50, or 75 mg) or placebo. The primary endpoint was ADHD-RS-IV total score change from baseline at end of study (EOS). RESULTS: Least squares mean (95% confidence interval [CI]) treatment differences for ADHD-RS-IV total score changes from baseline to EOS significantly favored triple-bead MAS (all doses combined: -10...
April 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28413900/efficacy-of-cognitive-behavioral-therapy-with-and-without-medication-for-adults-with-adhd
#11
Mariya V Cherkasova, Lisa R French, Cassidy A Syer, Lorne Cousins, Harry Galina, Yasaman Ahmadi-Kashani, Lily Hechtman
OBJECTIVE: Recent trials have demonstrated efficacy of cognitive behavioral therapy (CBT) in medicated adults with ADHD. Efficacy of CBT in unmedicated versus medicated adults remains mostly unknown. We evaluated the effects of group CBT alone versus combined with medication on ADHD symptoms and functional outcomes in adult patients. METHOD: Eighty-eight adults with ADHD received 12 manualized group CBT sessions, accompanied by individual coaching, either without ( n = 46) or with ( n = 42) medication...
October 1, 2016: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28412886/a-long-term-open-label-safety-study-of-triple-bead-mixed-amphetamine-salts-shp465-in-adults-with-adhd
#12
Lenard A Adler, Glen Frick, Brian Yan
OBJECTIVE: The aim of this study was to evaluate the long-term safety of triple-bead mixed amphetamine salts (MAS) in adults with ADHD. METHOD: Adults meeting Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; DSM-IV-TR) ADHD criteria and satisfying study criteria from one of two antecedent studies were enrolled in this 52-week (dose titration, 4 weeks; dose maintenance, 11 months) open-label extension. The protocol included 12.5- to 75-mg triple-bead MAS but was amended to a maximum of 50-mg triple-bead MAS...
April 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28412880/comment-concerning-cherkasova-et-al-2016-efficacy-of-cognitive-behavioral-therapy-with-and-without-medication-for-adults-with-adhd
#13
Mary V Solanto
No abstract text is available yet for this article.
April 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28412445/methylphenidate-effects-in-the-young-brain-friend-or-foe
#14
REVIEW
Sara Loureiro-Vieira, Vera Marisa Costa, Maria de Lourdes Bastos, Félix Carvalho, João Paulo Capela
Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent neuropsychiatry disorders in children and adolescents, and methylphenidate (MPH) is a first-line stimulant drug available worldwide for its treatment. Despite the proven therapeutic efficacy, concerns have been raised regarding the possible consequences of chronic MPH exposure during childhood and adolescence. Disturbances in the neurodevelopment at these crucial stages are major concerns given the unknown future life consequences...
April 13, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28409677/circadian-pattern-of-motor-activity-in-adults-with-attention-deficit-hyperactivity-disorder
#15
Lorenzo Tonetti, Andreas Conca, Giancarlo Giupponi, Vincenzo Natale
This study aims to describe the 24-hour activity rhythm in adults with attention-deficit/hyperactivity disorder (ADHD). A total of 18 ADHD patients and 37 healthy controls (HCs) wore an actigraph for 7 days. ADHD patients showed higher motor activity than HCs at 4:00, 6:00, 15:00 and 16:00 hour. Within the theoretical framework of the two-process model of sleep regulation, the observed data may be explained by lower homeostatic sleep pressure in ADHD. This could lead to an increase in motor activity in the second half of the night, when sleep need decreases more rapidly, and in the first half of the afternoon, when patients do not experience the typical post-lunch dip...
April 14, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28409230/binocular-rivalry-transitions-predict-inattention-symptom-severity-in-adult-adhd
#16
Aiste Jusyte, Natalia Zaretskaya, Nina Maria Höhnle, Andreas Bartels, Michael Schönenberg
Attention deficit and hyperactivity disorder (ADHD) is a prevalent childhood disorder that is often maintained throughout the development and persists into adulthood. Established etiology models suggest that deficient inhibition underlies the core ADHD symptoms. While experimental evidence for impaired motor inhibition is overwhelming, little is known about the sensory inhibition processes, their changes throughout the development, and the relationship to ADHD symptoms. Here, we used the well-established binocular rivalry (BR) paradigm to investigate for the very first time the inhibitory processes related to visual perception in adults with ADHD...
April 13, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28406942/the-brain-anatomy-of-attention-deficit-hyperactivity-disorder-in-young-adults-a-magnetic-resonance-imaging-study
#17
Jean-G Gehricke, Frithjof Kruggel, Tanyaporn Thampipop, Sharina Dyan Alejo, Erik Tatos, James Fallon, L Tugan Muftuler
BACKGROUND: This is one of the first studies to examine the structural brain anatomy and connectivity associated with an ADHD diagnosis and child as well as adult ADHD symptoms in young adults. It was hypothesized that an adult ADHD diagnosis and in particular childhood symptoms, are associated with widespread changes in the brain macro- and microstructure, which can be used to develop a morphometric biomarker for ADHD. METHODS: Voxel-wise linear regression models were used to examine structural and diffusion-weighted MRI data in 72 participants (31 young adults with ADHD and 41 controls without ADHD) in relation to diagnosis and the number of self-reported child and adult symptoms...
2017: PloS One
https://www.readbyqxmd.com/read/28406351/substance-use-in-undergraduate-students-with-histories-of-attention-deficit-hyperactivity-disorder-adhd-the-role-of-impulsivity
#18
Theresa E Egan, Anne E Dawson, Brian T Wymbs
BACKGROUND: Emerging adulthood (18-25 years old) is regarded as a time of identity exploration that includes a peak in risky behaviors, such as substance use and misuse. Attention-deficit/hyperactivity disorder (ADHD) is also associated with greater levels of risky behaviors, including substance use and misuse; however, there is a lack of research on substance use by emerging adults with ADHD, in particular the potential mechanisms that may facilitate this risk. OBJECTIVES: The present study builds on the existing research regarding the association between ADHD and substance use by examining roles of multiple facets of impulsivity in facilitating this association during emerging adulthood...
April 13, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28401487/perception-in-attention-deficit-hyperactivity-disorder
#19
REVIEW
Anselm B M Fuermaier, Philippa Hüpen, Stefanie M De Vries, Morgana Müller, Francien M Kok, Janneke Koerts, Joost Heutink, Lara Tucha, Manfred Gerlach, Oliver Tucha
A large body of research demonstrated that individuals with attention deficit hyperactivity disorder (ADHD) suffer from various neuropsychological deficits. In contrast, less is known and only divergent evidence exists on perceptual functions of individuals with ADHD. This is problematic as neuropsychological and perceptual functions are closely interrelated and are often difficult to disentangle in behavioral assessments. This study presents the conduct and results of a systematic literature review on perceptual functions in children and adults with ADHD...
April 11, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/28398986/living-with-symptoms-of-attention-deficit-hyperactivity-disorder-in-adulthood-a-systematic-review-of-qualitative-evidence
#20
Merete B Bjerrum, Preben U Pedersen, Palle Larsen
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) relates to four dimensions of behavior: inattentiveness, restlessness, impulsiveness and hyperactivity. Symptoms affect multiple areas of daily life such as academic performance and social functioning. Despite the negative effects of ADHD, people diagnosed with ADHD do not necessarily regard themselves as being impaired. However, it is unclear how adults with ADHD experience and manage their symptoms. OBJECTIVES: To identify and synthesize the best available evidence on how adults experience living with ADHD...
April 2017: JBI Database of Systematic Reviews and Implementation Reports
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