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https://www.readbyqxmd.com/read/29451590/by-the-book-adhd-prevalence-in-medical-students-varies-with-analogous-methods-of-addressing-dsm-items
#1
Paulo Mattos, Bruno P Nazar, Rosemary Tannock
OBJECTIVE: The marked increase in the prevalence of attention-deficit/hyperactivity disorder (ADHD) among university students gives rise to questions about how best to diagnose in this setting. The aim of the present study was to calculate ADHD prevalence in a large non-clinical sample of medical students using a stepwise design and to determine whether ADHD diagnosis varies if interviewees use additional probing procedures to obtain examples of positive DSM items. METHODS: A total of 726 students were screened with the Adult Self-Report Scale (ASRS) and invited for an interview with the Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) adapted for adults...
February 15, 2018: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/29450242/one-year-abstinence-improves-adhd-symptoms-among-patients-with-polysubstance-use-disorder
#2
Egon Hagen, Aleksander H Erga, Sverre M Nesvåg, James R McKay, Astri J Lundervold, Espen Walderhaug
Introduction: Attention-deficit/hyperactivity disorder (ADHD) is a common comorbid disorder in patients suffering from substance use disorder (SUD). Individuals with co-occurring SUD and ADHD are more likely than SUD patients without ADHD to have developed SUD at a younger age, be polysubstance users, and need inpatient treatment more often. The present study investigates whether individuals with polysubstance use disorder who remain abstinent for a year after entering treatment have a more substantial reduction in ADHD symptoms than those who relapsed and controls...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29442378/-shine-bright-like-a-diamond-is-research-on-high-functioning-adhd-at-last-entering-the-mainstream
#3
EDITORIAL
Klaus-Peter Lesch
The paper by Greven and colleagues (this issue) is intensifying discussion how research on attention-deficit/hyperactivity disorder (ADHD) can be moved away from the deficit-focused view to a concept, which is oriented towards resources a patient might be able to recruit to function at a high-level despite impairments. To promote understanding of high-functioning (HF)-ADHD, more longitudinal studies are required employing neuropsychologic, neuroimaging and neurobiologic approaches, with focus on compensatory mechanisms during fronto-striatal-amygdala maturation and adult plasticity as well as epigenetic modification marker screening strategies to identify homoeostatic processes of resilience in endophenotypic traits related to coping styles of target groups...
March 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29435654/standardised-assessment-of-functioning-in-adhd-consensus-on-the-icf-core-sets-for-adhd
#4
Sven Bölte, Soheil Mahdi, David Coghill, Susan Shur-Fen Gau, Mats Granlund, Martin Holtmann, Sunil Karande, Florence Levy, Luis A Rohde, Wolfgang Segerer, Petrus J de Vries, Melissa Selb
Attention-deficit/hyperactivity disorder (ADHD) is associated with significant impairments in social, educational, and occupational functioning, as well as specific strengths. Currently, there is no internationally accepted standard to assess the functioning of individuals with ADHD. WHO's International Classification of Functioning, Disability and Health-child and youth version (ICF) can serve as a conceptual basis for such a standard. The objective of this study is to develop a comprehensive, a common brief, and three age-appropriate brief ICF Core Sets for ADHD...
February 12, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29424567/neuropsychological-assessment-of-adults-with-adhd-a-delphi-consensus-study
#5
Anselm B M Fuermaier, Jan A Fricke, Stefanie M de Vries, Lara Tucha, Oliver Tucha
Within the clinical evaluation of adults with attention deficit hyperactivity disorder (ADHD), cognitive functions are often assessed to characterize individual cognitive problems and guide treatment planning. However, the composition of an adequate neuropsychological assessment battery remains difficult given the large number of cognitive functions that can be distinguished, the variety of available tools to assess these functions, as well as the cognitive heterogeneity that has been observed between individuals with ADHD...
February 9, 2018: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/29423564/interpretation-of-ambiguous-facial-affect-in-adults-with-attention-deficit-hyperactivity-disorder
#6
Alexander Schneidt, Aiste Jusyte, Michael Schönenberg
In addition to impairments in cognitive functioning, attention-deficit/hyperactivity disorder (ADHD) is associated with deficits in interpersonal functioning as well which are assumed to stem from a distorted perception or interpretation of affective information. While previous research suggests that the decoding of negatively valenced facial stimuli is impaired, less is known about the potential interpretation biases in ADHD which are linked to other externalizing psychopathologies. The present study investigated interpretation biases in adults with ADHD (N = 65) and controls (N = 49) using ambiguous facial stimuli (angry/happy, angry/fearful, fearful/happy blends) with different proportions of each emotion...
February 8, 2018: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/29419345/validation-of-the-expanded-versions-of-the-adult-adhd-self-report-scale-v1-1-symptom-checklist-and-the-adult-adhd-investigator-symptom-rating-scale
#7
Michael J Silverstein, Stephen V Faraone, Samuel Alperin, Terry L Leon, Joseph Biederman, Thomas J Spencer, Lenard A Adler
OBJECTIVE: The aim of this study is to validate the Adult ADHD Self-Report Scale (ASRS) and Adult ADHD Investigator Symptom Rating Scale (AISRS) expanded versions, including executive function deficits (EFDs) and emotional dyscontrol (EC) items, and to present ASRS and AISRS pilot normative data. METHOD: Two patient samples (referred and primary care physician [PCP] controls) were pooled together for these analyses. RESULTS: Final analysis included 297 respondents, 171 with adult ADHD...
February 1, 2018: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29414488/examining-social-supply-among-nonmedical-prescription-stimulant-users-in-the-san-francisco-bay-area
#8
Fiona Murphy, Sheigla Murphy, Paloma Sales, Nicholas Lau
In the US, prescription stimulants are prescribed for a variety of conditions including attention deficit hyperactivity disorder (ADHD) and narcolepsy. Over the last two decades, dramatic increases in stimulant prescriptions have led to greater availability and increased risk for diversion and nonmedical use. Our own and other investigators' findings indicate that many drug "suppliers" do not fit into the traditional image of drug "dealers." These suppliers typically do not identify themselves as "dealers," but instead understand their drug distribution as sharing with people they know...
January 30, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29411333/a-review-of-childhood-behavioral-problems-and-disorders-in-the-development-of-obesity-attention-deficit-hyperactivity-disorder-autism-spectrum-disorder-and-beyond
#9
REVIEW
Brittany E Matheson, Dawn M Eichen
PURPOSE OF REVIEW: Given the high rates of pediatric and adult obesity, it is imperative to identify early risk factors that might contribute to excess weight gain. This review aims to investigate the relationship between childhood behavioral problems with the development and persistence of obesity. Specifically, this review highlights the association of obesity with (1) neurocognitive constructs, such as executive functioning and inhibition/impulsivity, and (2) disorders commonly diagnosed in childhood, including attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD)...
February 6, 2018: Current Obesity Reports
https://www.readbyqxmd.com/read/29411149/pharmacological-treatment-of-attention-deficit-hyperactivity-disorder-during-pregnancy-and-lactation
#10
REVIEW
Asher Ornoy
INTRODUCTION: Attention deficit/hyperactivity disorder (ADHD) is a neurobehavioral problem found in 2-5% of adults. Stimulants and drugs that affect the dopaminergic, noradrenergic and/or serotonergic systems are effective treatment and are increasingly prescribed to women at child bearing age. It is consequently important that reliable information on the safety of these drugs in pregnancy is available so that appropriate therapeutic choices can be made. RESULTS: The data on stimulants (methylphenidate and amphetamines) are generally showing that there is no increase in the rate of major congenital anomalies...
February 6, 2018: Pharmaceutical Research
https://www.readbyqxmd.com/read/29409566/brain-behavior-patterns-define-a-dimensional-biotype-in-medication-na%C3%A3-ve-adults-with-attention-deficit-hyperactivity-disorder
#11
Hsiang-Yuan Lin, Luca Cocchi, Andrew Zalesky, Jinglei Lv, Alistair Perry, Wen-Yih Isaac Tseng, Prantik Kundu, Michael Breakspear, Susan Shur-Fen Gau
BACKGROUND: Childhood-onset attention-deficit hyperactivity disorder (ADHD) in adults is clinically heterogeneous and commonly presents with different patterns of cognitive deficits. It is unclear if this clinical heterogeneity expresses a dimensional or categorical difference in ADHD. METHODS: We first studied differences in functional connectivity in multi-echo resting-state functional magnetic resonance imaging (rs-fMRI) acquired from 80 medication-naïve adults with ADHD and 123 matched healthy controls...
February 7, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29406596/novelty-related-behavior-of-young-and-adult-dat-ko-rats-implication-for-cognitive-and-emotional-phenotypic-patterns
#12
Annalisa Adinolfi, Cristiana Carbone, Damiana Leo, Raul R Gainetdinov, Giovanni Laviola, Walter Adriani
ADHD is a neuro-psychiatric disorder characterized by a developmentally inappropriate, pervasive and persistent pattern of severe inattention, hyper-activity and impulsivity. Despite onset in early childhood, ADHD may continue into adulthood with substantial impairment in social, academic and occupational functioning. A new animal model of this disorder was developed in rats with genetic deletion of the dopamine transporter (DAT) gene (dopamine transporter knockout rats; DAT-KO rats). We analyzed the behavior of DAT-KO rats for a deeper phenotypical characterization of this model...
February 6, 2018: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29397534/chronic-methylphenidate-alters-tonic-and-phasic-glutamate-signaling-in-the-frontal-cortex-of-a-freely-moving-rat-model-of-adhd
#13
Erin M Miller, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhardt, Paul E A Glaser
Glutamate dysfunction has been implicated in a number of substance of abuse studies, including cocaine and methamphetamine. Moreover, in attention-deficit/hyperactivity disorder (ADHD), it has been discovered that when the initiation of stimulant treatment occurs during adolescence, there is an increased risk of developing a substance use disorder later in life. The spontaneously hypertensive rat (SHR) serves as a phenotype for ADHD and studies have found increased cocaine self-administration in adult SHRs when treated with the stimulant methylphenidate (MPH) during adolescence...
February 3, 2018: Neurochemical Research
https://www.readbyqxmd.com/read/29396361/pattern-of-executive-functioning-in-adolescents-with-epilepsy-a-multimethod-measurement-approach
#14
Avani C Modi, Jennifer Vannest, Angela Combs, Luke Turnier, Shari L Wade
Youth with epilepsy demonstrate deficits in executive functioning (EF), the skills necessary for goal-directed behavior (e.g., problem-solving, initiating, monitoring, organization, planning, and working memory). Despite 30-50% of youth with epilepsy demonstrating EF deficits, no extant studies have utilized both performance and questionnaire-based measures to examine the pattern of EF deficits in adolescents with epilepsy. Study aims were to 1) identify the pattern of EF deficits in adolescents with epilepsy and 2) identify which assessment tools are most sensitive to EF deficits in this population (adolescents, ages 13-17, with epilepsy)...
January 20, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29392209/methylphenidate-attenuates-the-response-to-cold-pain-but-not-to-aversive-auditory-stimuli-in-healthy-human-a-double-blind-randomized-controlled-study
#15
Dorit Pud, Eelena Broitman, Omar Hameed, Erica Suzan, Joshua Aviram, May Haddad, Salim Hadad, Rafi Shemesh, Elon Eisenberg
Introduction: We recently showed that the psycho-stimulant norepinephrine-dopamine reuptake inhibitor methylphenidate (MP) prolonged cold pain threshold and tolerance in adults with attention-deficit hyperactivity disorder (ADHD). Objectives: The objectives of the present study were to: (1) examine whether MP has antinociceptive properties in healthy men; (2) test MP's effects on responses to aversive auditory stimuli. The underlying aim was to determine whether MP exerts antinociceptive properties or more generalized, nonspecific attenuating effects on different aversive sensory modalities...
May 2017: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29391802/adhd-and-lifestyle-habits-in-czech-adults-a-national-sample
#16
Simon Weissenberger, Radek Ptacek, Martina Vnukova, Jiri Raboch, Martina Klicperova-Baker, Lucie Domkarova, Michal Goetz
Background: Adult attention-deficit/hyperactivity disorder (ADHD) has been added as a diagnosis to the Diagnostic and Statistical Manual of Mental Disorders version 5 (DSM5) in 2013, thus making ADHD, which has been classically known as a childhood disorder, a life-long disorder. Those suffering from the condition show very specific behavioral traits, which manifest as lifestyle habits; they also show comorbidities that can be the symptoms and/or consequences of certain lifestyles. Materials and methods: The targeted population was adults aged 18-65 years...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29382897/integrative-genomic-analysis-of-methylphenidate-response-in-attention-deficit-hyperactivity-disorder
#17
Mireia Pagerols, Vanesa Richarte, Cristina Sánchez-Mora, Paula Rovira, María Soler Artigas, Iris Garcia-Martínez, Eva Calvo-Sánchez, Montse Corrales, Bruna Santos da Silva, Nina Roth Mota, Marcelo Moraes Victor, Luis Augusto Rohde, Eugenio Horacio Grevet, Claiton Henrique Dotto Bau, Bru Cormand, Miguel Casas, Josep Antoni Ramos-Quiroga, Marta Ribasés
Methylphenidate (MPH) is the most frequently used pharmacological treatment in children with attention-deficit/hyperactivity disorder (ADHD). However, a considerable interindividual variability exists in clinical outcome. Thus, we performed a genome-wide association study of MPH efficacy in 173 ADHD paediatric patients. Although no variant reached genome-wide significance, the set of genes containing single-nucleotide polymorphisms (SNPs) nominally associated with MPH response (P < 0.05) was significantly enriched for candidates previously studied in ADHD or treatment outcome...
January 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29378061/young-adult-outcomes-for-children-with-22q11-deletion-syndrome-and-comorbid-adhd
#18
Lea E Taylor, Wendy R Kates, Wanda Fremont, Kevin M Antshel
Background: 22q11.2 deletion syndrome (22q11DS) is a common microdeletion syndrome associated with a variety of negative health, cognitive, emotional, and behavioral outcomes. 22q11DS is comorbid with many psychiatric disorders including attention-deficit/hyperactivity disorder (ADHD). The current study aimed to investigate the cognitive, behavioral, and functional outcomes that a childhood ADHD diagnosis predicts to in adulthood. Methods: This longitudinal study followed 52 individuals with 22q11DS over 9 years...
January 25, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29375629/clinical-utility-of-screening-for-anxiety-and-depression-in-children-with-tourette-syndrome
#19
Leonie Marwitz, Tamara Pringsheim
Background: Tourette syndrome (TS) is often co-morbid with attention deficit hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD). Studies of TS, anxiety and depression have found variable results depending on study methodology and sample characteristics. Our aim was to examine the clinical utility of routine screening for anxiety and depression in children with TS. Methods: Using a clinic-based sample, we evaluated the proportion of children with TS meeting diagnostic criteria for ADHD, OCD, generalized anxiety disorder (GAD), separation anxiety disorder (SAD), and major depressive disorder (MDD); the frequency of above average anxiety and depressive symptoms using the Multidimensional Anxiety Scale for Children (MASC) and the Children's Depression Inventory (CDI); and the association between diagnoses and symptom severity...
January 2018: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29373615/is-binge-eating-a-cognitive-disorder-results-from-the-international-mood-disorders-collaborative-project
#20
Yena Lee, Nicole E Carmona, Margarita Shekotikhina, Mehala Subramaniapillai, Rodrigo B Mansur, Danielle S Cha, Jae-Hon Lee, JungGoo Lee, Aileen J Zhou, Roman M Dale, David J Muzina, Sidney H Kennedy, Roger S McIntyre
BACKGROUND: Individuals with binge eating disorder (BED) are differentially affected by attention-deficit/hyperactivity disorder (ADHD), obesity, and substance use disorder. We have investigated to what extent cognitive deficits are relevant to binge eating behavior (BEB). METHODS: Data from the International Mood Disorders Collaborative Project were retrospectively and cross-sectionally analyzed to compare individuals with and without BEB on measures of anhedonia and general cognitive functions (n = 566)...
February 2018: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
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