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https://www.readbyqxmd.com/read/29690816/is-motor-activity-during-cognitive-assessment-an-indicator-for-feigned-attention-deficit-hyperactivity-disorder-adhd-in-adults
#1
Anselm B M Fuermaier, Oliver Tucha, Janneke Koerts, Tabea S Send, Matthias Weisbrod, Steffen Aschenbrenner, Lara Tucha
OBJECTIVES: Several approaches, ranging from self-ratings of symptoms and impairments to objective neuropsychological testing, have been utilized during clinical evaluation in order to assess symptom and performance validity of individuals with attention-deficit/hyperactivity disorder (ADHD) in adulthood. Motor activity has not been considered yet in this context, which is surprising given that hyperactivity is a prominent characteristic of ADHD. Hence, the goal of the present study was to explore the incremental value of motor activity when assessing the credibility of individuals with adult ADHD at clinical evaluation...
April 25, 2018: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/29687930/deficient-neural-activity-subserving-decision-making-during-reward-waiting-time-in-intertemporal-choice-in-adult-adhd
#2
Ayako Todokoro, Saori C Tanaka, Yuki Kawakubo, Noriaki Yahata, Ayaka Ishii-Takahashi, Yukika Nishimura, Yukiko Kano, Fumio Ohtake, Kiyoto Kasai
AIM: Impulsivity, which significantly affects social adaptation, is an important target behavioral characteristic in interventions for attention deficit hyperactivity disorder (ADHD). Typically, people are willing to wait longer to acquire greater rewards. Impulsivity in ADHD may be associated with brain dysfunction in decision making involving waiting behavior under such situations. We tested the hypothesis that brain circuitry during a period of waiting, i.e., prior to the acquisition of reward, is altered in adults with ADHD...
April 24, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29683192/investigating-late-onset-adhd-a-population-cohort-investigation
#3
Miriam Cooper, Gemma Hammerton, Stephan Collishaw, Kate Langley, Ajay Thapar, Søren Dalsgaard, Evie Stergiakouli, Kate Tilling, George Davey Smith, Barbara Maughan, Michael O'Donovan, Anita Thapar, Lucy Riglin
BACKGROUND: Adult ADHD has been assumed to be a continuation of childhood-onset ADHD. However, recent studies have identified individuals with ADHD in adulthood who have not had ADHD in childhood. Whether or not these individuals have a 'typical' neurodevelopmental profile is not clear. METHODS: We tested two explanations for the emergence of apparent late-onset ADHD symptomatology using the ALSPAC epidemiological cohort, by grouping individuals according to their scores on the Strengths and Difficulties Questionnaire (SDQ) hyperactivity subscale at ages 12 and 17 years...
April 23, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29682794/genetic-associations-with-childhood-brain-growth-defined-in-two-longitudinal-cohorts
#4
Eszter Szekely, Tae-Hwi Linus Schwantes-An, Cristina M Justice, Jeremy A Sabourin, Philip R Jansen, Ryan L Muetzel, Wendy Sharp, Henning Tiemeier, Heejong Sung, Tonya J White, Alexander F Wilson, Philip Shaw
Genome-wide association studies (GWASs) are unraveling the genetics of adult brain neuroanatomy as measured by cross-sectional anatomic magnetic resonance imaging (aMRI). However, the genetic mechanisms that shape childhood brain development are, as yet, largely unexplored. In this study we identify common genetic variants associated with childhood brain development as defined by longitudinal aMRI. Genome-wide single nucleotide polymorphism (SNP) data were determined in two cohorts: one enriched for attention-deficit/hyperactivity disorder (ADHD) (LONG cohort: 458 participants; 119 with ADHD) and the other from a population-based cohort (Generation R: 257 participants)...
April 22, 2018: Genetic Epidemiology
https://www.readbyqxmd.com/read/29681876/null-tdcs-effects-in-a-sustained-attention-task-the-modulating-role-of-learning
#5
Noa Jacoby, Michal Lavidor
The purpose of this study was to investigate sustained attention through modulation of the fronto-cerebral network with transcranial direct current stimulation (tDCS) in adults with attention-deficit/hyperactivity disorder (ADHD) and control participants. Thirty-seven participants (21 with ADHD) underwent three separate sessions (baseline, active tDCS, and sham) and performed the MOXO Continuous Performance Test (CPT). We applied double anodal stimulation of 1.8 mA tDCS for 20 min over the left and right dorsolateral prefrontal cortex (DLPFC), with the cathode over the cerebellum...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29671768/managing-complexity-exploring-decision-making-on-medication-by-young-adults-with-adhd
#6
Louise C Druedahl, Sofia Kälvemark Sporrong
Attention-deficit hyperactivity disorder (ADHD) causes difficulties with hyperactivity, impulsivity and inattention. Treatment of ADHD includes both medication and non-pharmacological options. Knowledge of treatment preferences by young adults with ADHD is sparse. The objective of this study was to explore the beliefs and experiences of young adults with ADHD related to their medication treatment decisions. Data were collected in Denmark in 2016 through a focus group and individual in-depth interviews. Conventional content analysis was used...
April 19, 2018: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/29662527/stimulant-withdrawal-in-a-child-with-autism-spectrum-disorder-and-adhd-a-case-report
#7
Aneta Krakowski, Abel Ickowicz
Objective: To consider whether the concepts of tolerance and withdrawal to stimulant medications apply to a preadolescent female, affected by autism spectrum disorder (ASD) and treated for associated attention-deficit/hyperactivity disorder (ADHD). Methods: We describe the case history and review scientific English language literature pertaining to acute withdrawal effects associated with methylphenidate and amphetamine derivatives in children. Results: An 11-year-old female with ASD and ADHD referred to our clinic experienced vomiting, headaches, and light sensitivity following abrupt discontinuation of methylphenidate; she subsequently presented with migraines and marked malaise immediately after a dose reduction in lisdexamfetamine...
April 2018: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29661516/lisdexamfetamine-targets-amygdala-mechanisms-that-bias-cognitive-control-in-attention-deficit-hyperactivity-disorder
#8
Kurt P Schulz, Beth Krone, Lenard A Adler, Anne-Claude V Bédard, Stephanie Duhoux, Juan Pedraza, Sanweda Mahagabin, Jeffrey H Newcorn
BACKGROUND: Prefrontal-limbic circuits that form the neural architecture for emotion to influence behavior have been implicated in the pathophysiology of attention-deficit/hyperactivity disorder (ADHD) and represent a potentially important target of medication treatment that has not been substantively evaluated. This study tested the effect of the psychostimulant prodrug lisdexamfetamine dimesylate on amygdala activation and connectivity during the emotional bias of response execution and inhibition...
March 19, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29660590/detection-of-neurodevelopmental-diversity-in-memory-clinics-validation-of-a-self-report-measure
#9
Alon Seifan, Chiashin Shih, Katherine Hackett, Max J Pensack, Matthew W Schelke, Michael Lin, Hemali Patel, Christine A Ganzer, Mahreen Ahmed, Robert Krikorian, Peter Tamboer, Adolfo M Henriquez, Richard S Isaacson, Sheila Steinhof
BACKGROUND: Neurodevelopmental learning and attentional disorders (NLAD) such as dyslexia, dyscalculia and attention deficit hyperactivity disorder (ADHD) affect at least 6% of the adult population or more. They are associated with atypical cognitive patterns in early and adult life. The cognitive patterns of affected individuals in late life have never been described. One main challenge is detecting individuals in clinical settings during which mild cognitive changes could be confounding the clinical presentation...
April 13, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29656905/transcranial-direct-current-stimulation-improves-long-term-memory-deficits-in-an-animal-model-of-attention-deficit-hyperactivity-disorder-and-modulates-oxidative-and-inflammatory-parameters
#10
Douglas Teixeira Leffa, Bruna Bellaver, Artur Alban Salvi, Carla de Oliveira, Wolnei Caumo, Eugenio Horacio Grevet, Felipe Fregni, André Quincozes-Santos, Luis Augusto Rohde, Iraci L S Torres
BACKGROUND: Transcranial direct current stimulation (tDCS) is a technique that modulates neuronal activity and has been proposed as a potential therapeutic tool for attention-deficit/hyperactivity disorder (ADHD) symptoms. Although pilot studies have shown evidence of efficacy, its mechanism of action remains unclear. OBJECTIVE/HYPOTHESIS: We evaluated the effects of tDCS on behavioral (working and long-term memory) and neurochemical (oxidative and inflammatory parameters) outcomes related to ADHD pathophysiology...
April 5, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29655378/mindfulness-based-cognitive-therapy-v-treatment-as-usual-in-adults-with-adhd-a-multicentre-single-blind-randomised-controlled-trial-erratum
#11
Lotte Janssen, Cornelis C Kan, Pieter J Carpentier, Bram Sizoo, Sevket Hepark, Melanie P J Schellekens, A Rogier T Donders, Jan K Buitelaar, Anne E M Speckens
No abstract text is available yet for this article.
April 15, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29652105/associations-between-problematic-internet-use-and-psychiatric-symptoms-among-university-students-in-japan
#12
Momoko Kitazawa, Michitaka Yoshimura, Mayu Murata, Yuka Sato-Fujimoto, Hidefumi Hitokoto, Masaru Mimura, Kazuo Tsubota, Taishiro Kishimoto
AIM: Research on the adverse effects of internet use has gained importance recently. However, there is currently insufficient data on Japanese young adults' internet use, so we conducted a survey targeting Japanese university students to research Problematic Internet Use (PIU). We also investigated the relationship between PIU and multiple psychiatric symptoms. METHODS: A paper-based survey was conducted at five universities in Japan. Respondents were asked to fill out self-report scales regarding their internet dependency using the Internet Addiction Test (IAT)...
April 13, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29651258/associations-between-core-symptoms-of-attention-deficit-hyperactivity-disorder-and-both-binge-and-restrictive-eating
#13
Panagiota Kaisari, Colin T Dourish, Pia Rotshtein, Suzanne Higgs
Introduction: It is unclear whether core symptoms of attention deficit hyperactivity disorder (ADHD) relate to specific types of disordered eating and little is known about the mediating mechanisms. We investigated associations between core symptoms of ADHD and binge/disinhibited eating and restrictive eating behavior and assessed whether negative mood and/or deficits in awareness and reliance on internal hunger/satiety cues mediate these relationships. Methods: In two independent studies, we used a dimensional approach to study ADHD and disordered eating...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29644474/risk-factors-for-parental-psychopathology-a-study-in-families-with-children-or-adolescents-with-psychopathology
#14
L W Wesseldijk, G C Dieleman, F J A van Steensel, M Bartels, J J Hudziak, R J L Lindauer, S M Bögels, C M Middeldorp
The parents of children with psychopathology are at increased risk for psychiatric symptoms. To investigate which parents are mostly at risk, we assessed in a clinical sample of families with children with psychopathology, whether parental symptom scores can be predicted by offspring psychiatric diagnoses and other child, parent and family characteristics. Parental depressive, anxiety, avoidant personality, attention-deficit/hyperactivity (ADHD), and antisocial personality symptoms were measured with the Adult Self Report in 1805 mothers and 1361 fathers of 1866 children with a psychiatric diagnosis as assessed in a child and adolescent psychiatric outpatient clinic...
April 11, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29629842/the-prevalence-of-late-onset-adhd-in-a-clinically-referred-adult-sample
#15
Mary V Solanto
OBJECTIVE: Three recent prospective longitudinal studies of population cohorts reported nontrivial rates of "adult-onset" ADHD. Given that this result is at odds with the neurodevelopmental conceptualization of ADHD, as well as with general clinical experience, we obtained report of onset of symptoms in a clinical sample of adults diagnosed with ADHD. METHOD: One hundred four adults diagnosed with ADHD completed retrospective ratings of DSM-IV/DSM-5 ADHD symptoms between the ages of 5 and 12 years...
April 1, 2018: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29624671/practitioner-review-emotional-dysregulation-in-attention-deficit-hyperactivity-disorder-implications-for-clinical-recognition-and-intervention
#16
REVIEW
Stephen V Faraone, Anthony L Rostain, Joseph Blader, Betsy Busch, Ann C Childress, Daniel F Connor, Jeffrey H Newcorn
BACKGROUND: Because emotional symptoms are common in attention-deficit/hyperactivity disorder (ADHD) patients and associate with much morbidity, some consider it to be a core feature rather than an associated trait. Others argue that emotional symptoms are too nonspecific for use as diagnostic criteria. This debate has been difficult to resolve due, in part, to the many terms used to describe emotional symptoms in ADHD and to concerns about overlap with mood disorders. METHODS: We sought to clarify the nature of emotional symptoms in ADHD by reviewing conceptual and measurement issues and by examining the evidence base regarding specificity of such symptoms for ADHD...
April 6, 2018: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29619935/tourette-syndrome-in-a-longitudinal-perspective-clinical-course-of-tics-and-comorbidities-coexisting-psychopathologies-phenotypes-and-predictors
#17
Camilla Groth
Tourette syndrome (TS) is a childhood onset neurodevelopmental disorder characterised by motor and vocal tics and frequent associated comorbidities. The developmental trajectory of tic shows tic-onset in the age of 4-6, peak in the age of 10-12 and decline during adolescence, although only few and small longitudinal studies form the basis of this evidence. Recent studies suggest that comorbid obsessive-compulsive disorder (OCD), attention deficit-hyperactivity disorder (ADHD) and coexisting psychopathologies tend to persist and become more dominant in adolescence...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29617704/expectancy-effects-on-self-reported-attention-deficit-hyperactivity-disorder-symptoms-in-simulated-neurofeedback-a-pilot-study
#18
Grace J Lee, Julie A Suhr
Objective: Expectancy is a psychological factor that can impact treatment effectiveness. Research on neurofeedback for attention-deficit/hyperactivity disorder (ADHD) suggests expectancy may contribute to treatment outcomes, though evidence for expectancy as an explanatory factor is sparse. This pilot study investigated the effects of expectancies on self-reported ADHD symptoms in simulated neurofeedback. Method: Forty-six adults who were concerned that they had ADHD expected to receive active neurofeedback, but were randomly assigned to receive a placebo with false feedback indicating attentive (positive false feedback) or inattentive (negative false feedback) states...
March 31, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29617066/the-mixed-opioid-receptor-antagonist-naltrexone-mitigates-stimulant-induced-euphoria-a-double-blind-placebo-controlled-trial-of-naltrexone
#19
Thomas J Spencer, Pradeep Bhide, Jinmin Zhu, Stephen V Faraone, Maura Fitzgerald, Amy M Yule, Mai Uchida, Andrea E Spencer, Anna M Hall, Ariana J Koster, Leah Feinberg, Sarah Kassabian, Barbara Storch, Joseph Biederman
OBJECTIVE: Supratherapeutic doses of methylphenidate activate μ-opioid receptors, which are linked to euphoria. This study assessed whether naltrexone, a mixed μ-opioid antagonist, may attenuate the euphoric effects of stimulants, thereby minimizing their abuse potential in subjects with attention-deficit/hyperactivity disorder (ADHD). METHODS: We conducted a 6-week, double-blind, placebo-controlled, randomized clinical trial of naltrexone in adults with DSM-IV ADHD receiving open treatment with a long-acting formulation of methylphenidate (January 2013 to June 2015)...
March 13, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29614390/can-neuropsychological-testing-facilitate-differential-diagnosis-between-at-risk-mental-state-arms-for-psychosis-and-adult-attention-deficit-hyperactivity-disorder-adhd
#20
Erich Studerus, Salvatore Corbisiero, Nadine Mazzariello, Sarah Ittig, Letizia Leanza, Laura Egloff, Katharina Beck, Ulrike Heitz, Christina Andreou, Rolf-Dieter Stieglitz, Anita Riecher-Rössler
BACKGROUND: Patients with an at-risk mental state (ARMS) for psychosis and patients with attention-deficit/hyperactivity disorder (ADHD) have many overlapping signs and symptoms and hence can be difficult to differentiate clinically. The aim of this study was to investigate whether the differential diagnosis between ARMS and adult ADHD could be improved by neuropsychological testing. METHODS: 168 ARMS patients, 123 adult ADHD patients and 109 healthy controls (HC) were recruited via specialized clinics of the University of Basel Psychiatric Hospital...
March 31, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
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