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https://www.readbyqxmd.com/read/28549556/evaluation-of-a-commercial-automatic-treatment-planning-system-for-prostate-cancers
#1
Kanabu Nawa, Akihiro Haga, Akihiro Nomoto, Raniel A Sarmiento, Kenshiro Shiraishi, Hideomi Yamashita, Keiichi Nakagawa
Recent developments in Radiation Oncology treatment planning have led to the development of software packages that facilitate automated intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) planning. Such solutions include site-specific modules, plan library methods, and algorithm-based methods. In this study, the plan quality for prostate cancer generated by the Auto-Planning module of the Pinnacle(3) radiation therapy treatment planning system (v9.10, Fitchburg, WI) is retrospectively evaluated...
May 23, 2017: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/28546250/the-management-and-imaging-of-vestibular-schwannomas
#2
REVIEW
E P Lin, B T Crane
Vestibular schwannomas are the most common cerebellopontine angle tumor. During the past century, the management goals of vestibular schwannomas have shifted from total resection to functional preservation. Current treatment options include surgical resection, stereotactic radiosurgery, and observation. Imaging has become a crucial part of the initial screening, evaluation, and follow-up assessment of vestibular schwannomas. Recognizing and understanding the management objectives, various treatment modalities, expected posttreatment findings, and complications allows the radiologist to play an essential role in a multidisciplinary team by providing key findings relevant to treatment planning and outcome assessment...
May 25, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28545264/reduction-of-dose-to-the-contralateral-breast-by-superflab-use-in-radiation-therapy-for-mammary-carcinomas
#3
Akanksha Solanki, Athiyaman M, Hemalatha A, H S Kumar
Background: Radiation therapy is an integral part of multimodality treatment for locally advanced carcinoma of breast. Radiation doses to nearby critical normal structures like heart, lungs, and contralateral breast (CLB increases risk of second malignancies. In this study, we measured doses to the CLB and studied effects of a 1 cm thickness superflap. Materials and Methods: Fifty post-mastectomy carcinoma breast patients were included in the study.Radiation therapy of 50 Gy was planned in 25 fractions, 5 days a week, using the Eclipse Treatment Planning System version 8...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28541775/cellular-response-to-exponentially-increasing-and-decreasing-dose-rates-implications-for-treatment-planning-in-targeted-radionuclide-therapy
#4
Jay H Solanki, Thomas Tritt, Jordan B Pasternack, Julia J Kim, Calvin N Leung, Jason D Domogauer, Nicholas W Colangelo, Venkat R Narra, Roger W Howell
The treatment of cancer using targeted radionuclide therapy is of interest to nuclear medicine and radiation oncology because of its potential for killing tumor cells while minimizing dose-limiting toxicities to normal tissue. The ionizing radiations emitted by radiopharmaceuticals deliver radiation absorbed doses over protracted periods of time with continuously varying dose rates. As targeted radionuclide therapy becomes a more prominent part of cancer therapy, accurate models for estimating the biologically effective dose (BED) or equieffective dose given in 2 fractions (EQD2α/β) will become essential for treatment planning...
May 25, 2017: Radiation Research
https://www.readbyqxmd.com/read/28541023/correlation-between-biological-characteristics-of-thrombus-and-short-term-efficiency-of-thrombolytic-therapy-by-acoustic-radiation-force-impulse-imaging-technique
#5
Xiaolei Yi, Caifang Ni, Mingming Li, Qiong Wu, Yi Li
BACKGROUND: Evaluate the biological characteristics of lower extremity deep venous thrombosis by applying acoustic radiation force impulse imaging technique(ARFI), explore the correlation between the value of shear wave speed (SWV) and short-term efficacy of thrombolytic therapy as well as analyze the application value of shear wave velocity in predicting the short-term efficacy of thrombolytic therapy. METHODS: Examine acoustic radiation force impulse imaging for 120 patients with lower extremity deep venous thrombosis and measure the shear wave velocity values...
May 24, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28540667/neurocognitive-functioning-in-pediatric-craniopharyngioma-performance-before-treatment-with-proton-therapy
#6
Ashley S Fournier-Goodnight, Jason M Ashford, Thomas E Merchant, Frederick A Boop, Daniel J Indelicato, Lei Wang, Hui Zhang, Heather M Conklin
The goal of this study was to investigate the impact of patient-, disease-, and treatment-related variables upon neurocognitive outcomes in pediatric patients with craniopharyngioma prior to treatment with proton therapy or observation after radical resection. For all participants (N = 104), relevant clinical and demographic variables were attained and neurocognitive evaluations completed prior to irradiation or planned observation. One-sample t-tests were conducted to compare performance to published normative data...
May 24, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28535919/precision-iort-image-guided-intraoperative-radiation-therapy-igiort-using-online-treatment-planning-including-tissue-heterogeneity-correction
#7
Frank Schneider, Frederic Bludau, Sven Clausen, Jens Fleckenstein, Udo Obertacke, Frederik Wenz
BACKGROUND: To the present date, IORT has been eye and hand guided without treatment planning and tissue heterogeneity correction. This limits the precision of the application and the precise documentation of the location and the deposited dose in the tissue. Here we present a set-up where we use image guidance by intraoperative cone beam computed tomography (CBCT) for precise online Monte Carlo treatment planning including tissue heterogeneity correction. MATERIALS AND METHODS: An IORT was performed during balloon kyphoplasty using a dedicated Needle Applicator...
May 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28535918/polymer-gel-dosimeters-for-pretreatment-radiotherapy-verification-using-the-three-dimensional-gamma-evaluation-and-pass-rate-maps
#8
Ling-Ling Hsieh, Jiunn-I Shieh, Li-Ju Wei, Yi-Chun Wang, Kai-Yuan Cheng, Cheng-Ting Shih
Polymer gel dosimeters (PGDs) have been widely studied for use in the pretreatment verification of clinical radiation therapy. However, the readability of PGDs in three-dimensional (3D) dosimetry remain unclear. In this study, the pretreatment verifications of clinical radiation therapy were performed using an N-isopropyl-acrylamide (NIPAM) PGD, and the results were used to evaluate the performance of the NIPAM PGD on 3D dose measurement. A gel phantom was used to measure the dose distribution of a clinical case of intensity-modulated radiation therapy...
May 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28533801/computed-tomography-guided-implantation-of-125-i-seeds-brachytherapy-for-recurrent-multiple-pulmonary-oligometastases-initial-experience-and-results
#9
Jie Li, Lijuan Zhang, Wenhuan Xu, Teng Wang, Leyuan Zhou, Qigen Xie, Weiguo Wang, Yanyan Hua
PURPOSE: To retrospectively evaluate the efficacy and safety of computed tomography (CT)-guided percutaneous interstitial brachytherapy using (125)I radioactive seeds for multiple pulmonary metastatic tumors. MATERIAL AND METHODS: Between September 2013 and December 2015, 22 patients with multiple pulmonary metastases, who after conventional chemotherapy and trans-arterial chemoembolization (TACE) therapy were considered unable to withstand stereotactic body radiation therapy (SBRT), received CT-guided (125)I brachytherapy...
April 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28533050/dual-core-steered-non-rigid-registration-for-multi-modal-images-via-bi-directional-image-synthesis
#10
Xiaohuan Cao, Jianhua Yang, Yaozong Gao, Yanrong Guo, Guorong Wu, Dinggang Shen
In prostate cancer radiotherapy, computed tomography (CT) is widely used for dose planning purposes. However, because CT has low soft tissue contrast, it makes manual contouring difficult for major pelvic organs. In contrast, magnetic resonance imaging (MRI) provides high soft tissue contrast, which makes it ideal for accurate manual contouring. Therefore, the contouring accuracy on CT can be significantly improved if the contours in MRI can be mapped to CT domain by registering MRI with CT of the same subject, which would eventually lead to high treatment efficacy...
May 13, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28532508/is-it-possible-for-knowledge-based-planning-to-improve-intensity-modulated-radiation-therapy-plan-quality-for-planners-with-different-planning-experiences-in-left-sided-breast-cancer-patients
#11
Juanqi Wang, Weigang Hu, Zhaozhi Yang, Xiaohui Chen, Zhiqiang Wu, Xiaoli Yu, Xiaomao Guo, Saiquan Lu, Kaixuan Li, Gongyi Yu
BACKGROUND: Knowledge-based planning (KBP) is a promising technique that can improve plan quality and increase planning efficiency. However, no attempts have been made to extend the domain of KBP for planners with different planning experiences so far. The purpose of this study was to quantify the potential gains for planners with different planning experiences after implementing KBP in intensity modulated radiation therapy (IMRT) plans for left-sided breast cancer patients. METHODS: The model libraries were populated with 80 expert clinical plans from treated patients who previously received left-sided breast-conserving surgery and IMRT with simultaneously integrated boost...
May 22, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28530533/respiratory-motion-management-in-pet-ct-applications-and-clinical-usefulness
#12
Luca Guerra, Elena De Ponti, Sabrina Morzenti, Chiara Spadavecchia, Cinzia Crivellaro
Although breathing movement can introduce heavy bias in both image quality and quantitation, currently there is lack of interest for the respiratory motion management in PET/CT imaging. The respiratory gating technology has shown significant benefits on image quality, reducing motion related artifacts and increasing quantification. Indeed, many papers have demonstrated that there is a consistent increase of the Standardized Uptake Value (SUV) in gated PET images when compared to ungated ones, particularly for the small lesions located both in liver and in lung...
May 19, 2017: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/28530067/-stereotactic-ablative-body-radiation-sabr-a-new-therapeutic-option-for-treatment-of-stage-i-lung-cancer
#13
REVIEW
Sarit Appel, Zvi Symon
Stereotactic ablative radiotherapy (SABR) also known as stereotactic body radiation therapy (SBRT) offers a new therapeutic option for stage 1 lung cancer that cannot undergo surgery due to co-morbidities or patient refusal. This treatment evolved in the last decade thanks to technologic advancement of radiation therapy planning and delivery that allow real time imaging of the tumor and real time position correction before every treatment. Ultra high doses of radiation cause ablation of the target with very low collateral scatter dose to surrounding tissue...
November 2016: Harefuah
https://www.readbyqxmd.com/read/28529611/long-term-patterns-of-regional-failure-for-nasopharyngeal-carcinoma-following-intensity-modulated-radiation-therapy
#14
Fen Xue, Chaosu Hu, Xiayun He
PURPOSE: To analyze the long-term patterns of regional failure following intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC). METHODS: From January 2005 to December 2010, 275 non-metastatic NPC patients treated with IMRT were retrospectively enrolled. Patients staged as II (lymph nodes measuring 4 or more cm in diameter), III or IV also received chemotherapy. Failures were assessed as in-field or out-field relative to the pretreatment planning computed tomography data sets...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28529250/impact-of-jaw-position-accuracy-on-dose-variation-in-volumetric-modulated-arc-therapy-using-jaw-tracking
#15
Fumiyasu Matsubayashi, Yuki Koizumi, Ryo Takahashi, Minoru Yoshioka, Tomoharu Sato
The technique of jaw tracking can be used in volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT). In this technique, jaw tracks apertures of the multi leaf collimator (MLC) during irradiation. It is reported that dose variation is occurred by the changing accuracy of MLC position in VMAT and IMRT. Though jaw moves dynamically in the irradiation by using this technique, the influence of the jaw position accuracy on dose variation is not examined. The purpose of this study is to verify the influence of jaw position accuracy on dose variation in VMAT using jaw tracking...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28528679/evidence-based-peer-review-for-radiation-therapy-updated-review-of-the-literature-with-a-focus-on-tumour-subsite-and-treatment-modality
#16
M Huo, P Gorayski, M Poulsen, K Thompson, M B Pinkham
Technological advances in radiation therapy permit steep dose gradients from the target to spare normal tissue, but increase the risk of geographic miss. Suboptimal target delineation adversely affects clinical outcomes. Prospective peer review is a method for quality assurance of oncologists' radiotherapy plans. Published surveys suggest it is widely implemented. However, it may not be feasible to review every case before commencement of radiation therapy in all departments. The rate of plan changes following peer review of cases without a specific subsite or modality is typically around 10%...
May 18, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28528206/feasibility-of-atlas-based-active-bone-marrow-sparing-intensity-modulated-radiation-therapy-for-cervical-cancer
#17
Nan Li, Sonal S Noticewala, Casey W Williamson, Hanjie Shen, Igor Sirak, Rafal Tarnawski, Umesh Mahantshetty, Carl K Hoh, Kevin L Moore, Loren K Mell
BACKGROUND: To test the hypothesis that atlas-based active bone marrow (ABM)-sparing intensity modulated radiation therapy (IMRT) yields similar dosimetric results compared to custom ABM-sparing IMRT for cervical cancer patients. METHODS: We sampled 62 cervical cancer patients with pre-treatment FDG-PET/CT in training (n=32) or test (n=30) sets. ABM was defined as the subvolume of the pelvic bone marrow (PBM) with standardized uptake value (SUV) above the mean on the average FDG-PET image (ABMAtlas) vs...
May 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28527523/advances-in-radiation-oncology-what-to-consider
#18
REVIEW
John V Hegde, Allen M Chen, Robert K Chin
Treatment of squamous cell carcinoma of the head and neck is rapidly evolving due to changing patient populations, an emphasis on quality of life-related outcomes, and advances in radiotherapy concepts and techniques to meet these new demands. This review includes recent and ongoing studies that are potentially practice changing, including improvements in intensity-modulated radiotherapy planning, the use of deintensified regimens in the human papilloma virus-related setting, and adjuvant therapy after transoral robotic surgery...
May 17, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28527203/value-of-different-ultrasound-elastography-techniques-in-patients-with-venous-malformations-prior-to-and-after-sclerotherapy
#19
V I Teusch, A P Piehler, W Uller, R Müller-Wille, L Prantl, C Stroszczynski, W A Wohlgemuth, E M Jung
AIM: Comparison of different ultrasound elastography techniques for detection of changes after sclerotherapy within venous malformations. MATERIAL AND METHODS: In patients with venous malformations sonography was executed at exactly the same position prior to and after ethanol-gel sclerotherapy. Both examinations included B-Mode, vascular sonography with Color-Coded Duplex Sonography, and additional sonography with different elastography techniques (strain, qualitative and quantitative Acoustic Radiation Force Impulse (ARFI) elastography) with a linear transducer (6-9 MHz)...
May 19, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28526235/zero-echo-time-mri-only-treatment-planning-for-radiation-therapy-of-brain-tumors-after-resection
#20
C Boydev, B Demol, D Pasquier, H Saint-Jalmes, G Delpon, N Reynaert
Using magnetic resonance imaging (MRI) as the sole imaging modality for patient modeling in radiation therapy (RT) is a challenging task due to the need to derive electron density information from MRI and construct a so-called pseudo-computed tomography (pCT) image. We have previously published a new method to derive pCT images from head T1-weighted (T1-w) MR images using a single-atlas propagation scheme followed by a post hoc correction of the mapped CT numbers using local intensity information. The purpose of this study was to investigate the performance of our method with head zero echo time (ZTE) MR images...
May 16, 2017: Physica Medica: PM
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