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https://www.readbyqxmd.com/read/28829836/reference-intervals-of-echocardiographic-measurements-in-healthy-adult-dairy-goats
#1
Olga Szaluś-Jordanow, Michał Czopowicz, Lucjan Witkowski, Marcin Mickiewicz, Tadeusz Frymus, Iwona Markowska-Daniel, Emilia Bagnicka, Jarosław Kaba
OBJECTIVES: To determine references intervals for echocardiographic measurements in adult dairy goats. ANIMALS: 125 clinically healthy, adult dairy goats aged 2-9 years, belonging to two breeds-Polish Fawn Improved (PFI, n = 64, weight range from 46 to 73, median of 58.5kg) and Polish White Improved (PWI, n = 61, weight range from 48 to 80 kg, median of 67.9kg), closely related to French Alpine and Saanen, respectively. METHODS: Non-invasive transthoracic echocardiography examination was performed in unsedated goats in a standing position...
2017: PloS One
https://www.readbyqxmd.com/read/28829829/intermediate-cd14-cd16-monocytes-decline-after-transcatheter-aortic-valve-replacement-and-correlate-with-functional-capacity-and-left-ventricular-systolic-function
#2
Jonas Neuser, Paolo Galuppo, Daniela Fraccarollo, Jens Willig, Tibor Kempf, Dominik Berliner, Johann Bauersachs, Julian Daniel Widder
BACKGROUND: Transcatheter aortic valve replacement (TAVR) is the method of choice for patients with severe aortic valve stenosis, who are ineligible or at high risk for surgery. Though TAVR leads to a significant reduction in mortality, a notable amount of patients are re-hospitalized early after TAVR. Parameters or biomarkers predicting outcome are therefore needed to identify patients who benefit most. Specific monocyte subsets have been associated with cardiovascular diseases and were shown to possess prognostic value...
2017: PloS One
https://www.readbyqxmd.com/read/28829498/concomitant-mitral-valve-replacement-and-tricuspid-valvuloplasty-for-severe-mitral-stenosis
#3
X-D Hou, F Ding, X-K Wang, X-G Liu, K Yi, P Zhang, T You
OBJECTIVE: The purpose of this work is to analyze the clinical results of treating severe mitral stenosis (MS) with mild to moderate functional tricuspid regurgitation (FTR) with mitral valve replacement (MVR) alone or together with two different methods of tricuspid valvuloplasty (TVP). PATIENTS AND METHODS: We split 132 patients into three groups: simple MVR with 47 cases (control group), MVR+ TVP (De Vega loop reduction) with 45 cases (observation group 1) and MVR+ TVP (Edwards MC3 tricuspid forming ring implantation) with 40 cases (observation group 2)...
August 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28829347/abdominal-aortic-dissection-and-cold-intolerance-after-whole-body-cryotherapy-a-case-report
#4
Carlos R Cámara-Lemarroy, José R Azpiri-López, Luis A Vázquez-Díaz, Dionicio A Galarza-Delgado
Whole-body cryotherapy (WBC) involves short exposures to air temperatures below -100°C and is purported to enhance recovery after exercise and accelerate rehabilitation after injury. It is generally considered a procedure with few side effects, but there are no large studies that have established its safety profile. We present the case of a 56-year-old patient who developed an abdominal aortic dissection after receiving 15 sessions of WBC. The patient had no other strong risk factors for aortic dissection...
September 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28828934/long-term-outcome-and-quality-of-life-after-ruptured-abdominal-aortic-aneurysm-repair
#5
Hilin Yildirim, Guus W van Lammeren, Çagdas Ünlü, Eric P van Dongen, Rob Hw van de Mortel, Jean-Paul Pm de Vries
Objectives To evaluate long-term outcome and quality of life after open and endovascular repair of ruptured abdominal aortic aneurysms. Methods All consecutive ruptured abdominal aortic aneurysm patients at the St. Antonius Hospital treated for ruptured abdominal aortic aneurysm between January 2005 and January 2015 were included. Mortality, morbidity, and re-interventions within 30 days and during follow-up were registered. Quality of life was measured with Short Form-36 questionnaire among survivors. Additional subgroup analysis between open repair and endovascular repair was performed...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28828892/new-considerations-in-the-assessment-of-aortic-stenosis
#6
Lucy M Safi, Jonathan J Passeri, Michael H Picard
Calcific aortic stenosis (AS) is one of the most common acquired valvular heart diseases in industrialized nations. It is a slowly progressive disease and with the aging population, the prevalence of AS is expected to increase. Doppler echocardiography is used to classify patients based on severity of stenosis. Research efforts on how to better identify and risk-assess these patients are currently underway using advanced imaging modalities and serum biomarkers. Thus far, medications for AS prevention have been unsuccessful...
August 22, 2017: Future Cardiology
https://www.readbyqxmd.com/read/28828765/fast-track-extubation-in-adult-patients-on-pump-open-heart-surgery-at-a-tertiary-care-hospital
#7
Mohammad Irfan Akhtar, Hasanat Sharif, Mohammad Hamid, Khalid Samad, Fazal Hameed Khan
Background: Fast-track cardiac surgery programs have been established as the standard of cardiac surgical care. Studies have shown that early extubation in elective cardiac surgery patients, including coronary and non-coronary open-heart surgery patients does not increase perioperative morbidity and mortality. The objective of this observational study was to determine the success and failure profile of fast track extubation (FTE) practice in adult open-heart surgical patients. Methods: The study was conducted at cardiac operating room and Cardiac Intensive Care Unit (CICU) of a tertiary care hospital for a period of nine months, i...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28828684/transcatheter-closure-of-patent-ductus-arteriosus-in-children-with-the-occlutech-duct-occluder
#8
Meki Bilici, Fikri Demir, Alper Akın, Mehmet Türe, Hasan Balık, Mahir Kuyumcu
The aim of this study was to evaluate the feasibility, efficacy and safety of transcatheter closure of patent ductus arteriosus (PDA) with the Occlutech duct occluder (ODO) in children. We reviewed the clinical records of 71 patients who underwent percutaneous closure of PDA with an ODO between September 2014 and August 2016. The Occlutech duct occluder was applied to 71 patients during the study period (September 2014-August 2016), and the results were analyzed in this study. Forty-two of the patients were female and 29 male...
August 21, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28828679/transcatheter-aortic-valve-implantation-in-patients-with-a-reduced-left-ventricular-ejection-fraction-a-single-centre-experience-in-2000-patients-tavik-registry
#9
Gerhard Schymik, Panagiotis Tzamalis, Valentin Herzberger, Jens Bergmann, Peter Bramlage, Alexander Würth, Lars Oliver Conzelmann, Armin Luik, Holger Schröfel
BACKGROUND: Previous studies into the effect of a reduced left ventricular ejection fraction (EF) on the short- and long-term prognosis of patients undergoing transcatheter aortic valve implantation (TAVI) have reported conflicting findings. We analysed data from the Karlsruhe TAVI registry with the aim of addressing this question. METHODS AND RESULTS: Patients with aortic stenosis undergoing TAVI were divided into sub-groups according to EF: severely reduced (<30%; n = 109), reduced (≥30 and ≤40%; n = 201), and mid-range/preserved (>40%; n = 1690)...
August 21, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/28828510/prognostic-value-of-lymph-node-to-primary-tumor-standardized-uptake-value-ratio-in-endometrioid-endometrial-carcinoma
#10
Hyun Hoon Chung, Gi Jeong Cheon, Jae-Weon Kim, Noh-Hyun Park, Yong Sang Song
PURPOSE: To determine whether the relative metabolic activity of pelvic or para-aortic LN compared with that of primary tumor measured by preoperative [(18)F]FDG PET/CT scan has prognostic value in patients with endometrioid endometrial carcinoma. METHODS: We retrospectively reviewed patients with endometrioid endometrial carcinoma who underwent preoperative [(18)F]FDG PET/CT scans. Prognostic values of PET/CT-derived metabolic variables such as maximum standardized uptake value (SUV) of the primary endometrial carcinoma (SUVTumor) and LN (SUVLN), and the LN-to-endometrial carcinoma SUV ratio (SUVLN / SUVTumor) were assessed...
August 21, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28828117/iatrogenic-type-a-aortic-dissection-complicating-percutaneous-coronary-intervention-a-case-report
#11
Xiao-Zhou Du, Brett Memauri
Iatrogenic type A dissection caused by percutaneous coronary intervention is a rare but life-threatening condition. Computed tomographic angiography is an excellent diagnostic tool commonly utilized if such procedural complication is clinically suspected. There are, however, potential diagnostic challenges. Herein, we present an illustrative case of iatrogenic type A dissection successfully diagnosed on computed tomography angiography along with a potential diagnostic pitfall.
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28828105/incidental-retroaortic-left-innominate-vein-in-adult-patient
#12
Alexandre Semionov, John Kosiuk
Retro-aortic left innominate vein is a rare vascular abnormality, usually associated with congenital heart disease. Here we report a case of isolated retro-aortic left innominate vein in an adult female.
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28828104/pulmonary-artery-dissection-complicating-aortic-dissection-in-a-patient-with-bicuspid-aortic-valve-and-aortic-coarctation
#13
Minhaj S Khaja, Richard L Hallett
We report a case of a type A aortic dissection with extension into the main pulmonary artery through a sinus of Valsalva fistula. Echocardiography and computed tomographic angiography of the chest were performed and bicuspid aortic valve, hemopericardium, and dilatation of the aortic root were found. A Stanford type A dissection was seen, extending to the distal transverse thoracic aorta, and there was a communication between the dissection at the left sinus of Valsalva and the main pulmonary artery, where a dissection flap was detected at computed tomographic angiography...
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28828099/contrast-enhanced-magnetic-resonance-imaging-to-detect-chronic-aortic-dissection-complicated-by-acute-aortitis
#14
Kotaro Ouchi, Toru Sakuma, Kunihiko Fukuda, Michio Yoshitake
When chronic aortic dissection (CAD) is associated with aortic dilatation, the risk of aortic rupture increases. We report a case of CAD complicated by acute aortitis that was depicted in contrast-enhanced magnetic resonance imaging (MRI). Contrast-enhanced MRI allows early detection of subtle changes in the aortic wall as well as disease activity. Inflammation of aortic wall in the aortic dissection can be at higher risk of the dissected aortic expansion and rupture. When we recognize inflammation of unknown origin with CAD, contrast-enhanced MRI should be performed to rule out CAD complicated by acute aortitis may lead to catastrophic complications...
September 2017: Radiology case reports
https://www.readbyqxmd.com/read/28828046/modern-use-of-echocardiography-in-transcatheter-aortic-valve-replacement-an-up-date
#15
Cristina Caldararu, Serban Balanescu
Echocardiography is the cornerstone in the diagnosis of any valvular heart disease. The accurate diagnosis of aortic stenosis, the left ventricle function and the other heart valves evaluation are currently done by ultrasound alone. Prosthetic valve choice and dimensions prior to implantation can be done solely by proper use of echocardiography. The emergence of new methods to cure aortic stenosis such as trans-catheter aortic valve replacement (TAVR) emphasized the diagnostic value of cardiac ultrasound. The usefulness of echocardiography in TAVR can be divided in the baseline assessment (common to patients treated by conventional surgery), intra-procedural guidance of valve deployment and post-procedural follow-up...
December 2016: Mædica
https://www.readbyqxmd.com/read/28827891/jak2-stat3-pathway-was-associated-with-the-protective-effects-of-il-22-on-aortic-dissection-with-acute-lung-injury
#16
Wei Ren, Zhiwei Wang, Zhiyong Wu, Zhipeng Hu, Feifeng Dai, Jinxing Chang, Bowen Li, Huagang Liu, Yongle Ruan
Patients with aortic dissection (AD) may present acute lung injury (ALI) that may affect the prognosis. In this study, we aim to investigate the roles and mechanism of IL-22 in the pathogenesis of AD complicated with ALI. Six hundred and twenty-one AD patients were included, and the incidence of ALI and pulmonary CT findings were analyzed. Mouse ALI model was established through AngII, and then IL-22 injection and AG490 were given. The pathological changes, infiltration of inflammatory cells, and expression of STAT3 were determined...
2017: Disease Markers
https://www.readbyqxmd.com/read/28827606/effect-of-aortic-regurgitant-jet-direction-on-mitral-valve-leaflet-remodeling-a-real-time-three-dimensional-transesophageal-echocardiography-study
#17
Kensuke Hirasawa, Masaki Izumo, Taro Sasaoka, Takashi Ashikaga, Kengo Suzuki, Tomoo Harada, Mitsuaki Isobe, Yoshihiro J Akashi
Chronic aortic regurgitation (AR) induces mitral valve (MV) leaflet enlargement, although, its mechanism still remains unclear. This study aimed to clarify the influence of AR jet directions on the MV apparatus in patients with chronic AR. This study included 69 consecutive patients with severe chronic AR and 17 controls who underwent three-dimensional (3D) transesophageal echocardiography (TEE). The anterior mitral leaflet (AML), posterior mitral leaflet (PML) and MV annulus areas were measured at mid-diastole...
August 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28827474/p2y12-receptor-promotes-pressure-overload-induced-cardiac-remodeling-via-platelet-driven-inflammation-in-mice
#18
Lujin Wu, Fujie Zhao, Meiyan Dai, Huaping Li, Chen Chen, Jiali Nie, Peihua Wang, Dao Wen Wang
Inflammation plays a critical role in adverse cardiac remodeling and heart failure. The P2y12 receptor is one of the predominant activating receptors for platelets, thus initiating inflammatory responses under various diseases. In this study, we investigated the functional significance of P2y12-mediated platelet activation in pressure overload-induced cardiac remodeling. Notably, P2y12 knockout (P2y12(-)(/-)) mice exhibited suppressed transverse aortic constriction-induced changes in cardiac hypertrophy, collagen synthesis, inflammatory cell recruitment, and cardiac dysfunction...
August 21, 2017: Hypertension
https://www.readbyqxmd.com/read/28827473/restoration-of-circulating-mfge8-milk-fat-globule-egf-factor-8-attenuates-cardiac-hypertrophy-through-inhibition-of-akt-pathway
#19
Ke-Qiong Deng, Jing Li, Zhi-Gang She, Jun Gong, Wen-Lin Cheng, Fu-Han Gong, Xue-Yong Zhu, Yan Zhang, Zhihua Wang, Hongliang Li
Cardiac hypertrophy occurs in response to numerous stimuli like neurohumoral stress, pressure overload, infection, and injury, and leads to heart failure. Mfge8 (milk fat globule-EGF factor 8) is a secreted protein involved in various human diseases, but its regulation and function during cardiac hypertrophy remain unexplored. Here, we found that circulating MFGE8 levels declined significantly in failing hearts from patients with dilated cardiomyopathy. Correlation analyses revealed that circulating MFGE8 levels were negatively correlated with the severity of cardiac dysfunction and remodeling in affected patients...
August 21, 2017: Hypertension
https://www.readbyqxmd.com/read/28827412/macrophage-liver-kinase-b1-inhibits-foam-cell-formation-and-atherosclerosis
#20
Zhaoyu Liu, Huaiping Zhu, Xaoyan Dai, Cheng Wang, Ye Ding, Ping Song, Ming-Hui Zou
Rationale: Liver kinase B1 (LKB1) is a serine/threonine kinase and tumor suppressor, which regulates the homeostasis of hematopoietic cells and immune responses. Macrophages transform into foam cells upon taking-in lipids. No role for LKB1 in foam cell formation has previously reported. Objective: We sought to establish the role of LKB1 in atherosclerotic foam cell formation. Methods and Results: LKB1 expression was examined in human carotid atherosclerotic plaques and in western diet fed atherosclerosis-prone Ldlr(-/-) and ApoE(-/-) mice...
August 21, 2017: Circulation Research
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