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https://www.readbyqxmd.com/read/28544949/the-influence-of-shoe-aging-on-children-running-biomechanics
#1
Alexis Herbaut, Pascale Chavet, Maxime Roux, Nils Guéguen, Franck Barbier, Emilie Simoneau-Buessinger
Athletic children are prone to overuse injuries, especially at the heel and knee. Since footwear is an extrinsic factor of lower limb injury risk, the aim of this study was to assess the influence of shoe aging on children running biomechanics. Fourteen children active in sports participated in a laboratory biomechanical evaluation. A new pair of shoes was provided to each participant at an inclusion visit. Four months later, the participants performed a running task and their kinematics and kinetics were assessed both with their used shoes and with a new pair of shoes identical to the first...
May 17, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28540780/persistent-pathways-after-lung-radiofrequency-ablation-as-a-risk-factor-of-drain-placement
#2
Marie Lignieres, Nicolas Roux, Roch Giorgi, Jean-Yves Gaubert, Kathia Chaumoitre, Jean-Michel Bartoli, Vincent Vidal, Jean Izaaryene
PURPOSE: The risk factors of pneumothorax after lung radiofrequency (RF) ablation are long known. The objective was to demonstrate that the visualisation of an aeric RF path after the needle withdrawal was predictive of pneumothorax occurrence and chest tube placement. MATERIALS AND METHODS: A total of 70 patients were retrospectively included in this study. For each patient, we determined the pneumothorax risk factors (age, gender, previous surgery, emphysema, lesion size, distance between pleura and lesion), visualisation of a RF track, length and thickness, presence of pneumothorax, volume, chest tube placement, duration of drainage and hospital stay...
March 15, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28539445/structure-of-simian-immunodeficiency-virus-envelope-spikes-bound-with-cd4-and-monoclonal-antibody-36d5
#3
Guiqing Hu, Jun Liu, Kenneth H Roux, Kenneth A Taylor
The HIV-1/SIV envelope spike (Env) mediates the viral entry into host cells. The V3 loop of the gp120 component of the Env trimer contributes to the co-receptor binding site and is a target for neutralizing antibodies. We have used cryoelectron tomography to visualize the binding of CD4 and the V3 loop monoclonal antibody 36D5 to gp120 of the SIV Env. Our results show that 36D5 binds gp120 at the base of the V3 loop and suggest the antibody exerts its neutralization effect by blocking the co-receptor binding site...
May 24, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28539297/-efficacy-of-two-bariatric-surgeries-in-type-2-diabetic-patients-with-a-body-mass-index-of-25-27-5
#4
Hao Yu, Xiao-Jiang Dai, Hong-Bing Zhang, Yong-Tao Huang, Dong-Zhi Ran, Yuan Yang, Song-Hua Zeng, Zhi-Gao Song, Liang-Ping Wu
OBJECTIVE: To evaluate the therapeutic effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic duodenal-jejunal bypass with sleeve gastrectomy (SADJB-SG) in patients with type 2 diabetes mellitus and a low body mass index (BMI) of 25-27.5. METHODS: Thirty-one type 2 diabetic patients with a BMI of 25-27.5 underwent bariatric surgeries in the General Hospital of Guangzhou Military Command between August, 2013 and August, 2015. The patients receiving LRYGB (17 cases) and SADJB-SG (14 cases) were compared for physical indexes, glucose metabolism and of pancreatic islet function at 1 year after the surgeries...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28537566/intramural-gastric-hematoma-imitating-a-gastrointestinal-stromal-tumor-case-report-and-literature-review
#5
Arkadiusz Spychała, Piotr Nowaczyk, Aleksandra Budnicka, Ewa Antoniewicz, Dawid Murawa
The article presents a case report of a patient with an intramural gastric hematoma. Diagnostic examinations were suggestive of a suspected gastrointestinal stromal tumor Normal image was observed in gastroscopic examination while abdominal CT scan revealed a nodular lesion along the greater curvature of the stomach extending from the posterior wall and adjoining the pancreas and the spleen. The patient was qualified for surgical treatment. Laparotomy was performed followed by total gastric resection and Roux-en-Y reconstruction of the gastrointestinal tract...
April 30, 2017: Polski Przeglad Chirurgiczny
https://www.readbyqxmd.com/read/28536154/gastric-bypass-surgery-produces-a-durable-reduction-in-cardiovascular-disease-risk-factors-and-reduces-the-long-term-risks-of-congestive-heart-failure
#6
Peter N Benotti, G Craig Wood, David J Carey, Vishal C Mehra, Tooraj Mirshahi, Michelle R Lent, Anthony T Petrick, Christopher Still, Glenn S Gerhard, Annemarie G Hirsch
BACKGROUND: Obesity and its association with reduced life expectancy are well established, with cardiovascular disease as one of the major causes of fatality. Metabolic surgery is a powerful intervention for severe obesity, resulting in improvement in comorbid diseases and in cardiovascular risk factors. This study investigates the relationship between metabolic surgery and long-term cardiovascular events. METHODS AND RESULTS: A cohort of Roux-en-Y gastric bypass surgery (RYGB) patients was tightly matched by age, body mass index, sex, Framingham Risk Score, smoking history, use of antihypertension medication, diabetes mellitus status, and calendar year with a concurrent cohort of nonoperated control patients...
May 23, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28535389/human-memory-brain-state-dependent-effects-of%C3%A2-stimulation
#7
Simon Hanslmayr, Frederic Roux
A new study shows that direct stimulation of memory-relevant brain areas can enhance memory performance, but only when stimulation is applied during brain states associated with poor memory outcome - stimulation during optimal states results in a decrease in memory.
May 22, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28535280/invited-commentary-the-enduring-role-of-place-in-health-a-historic-perspective
#8
Yvette C Cozier
In public health, it has long been observed that "place"-specifically, where one lives-affects individual health, with the main research question distinguishing between the effects of "context" (defined as area characteristics) and "composition" (the characteristics of inhabitants) on health outcomes. There have been many studies in which the spatial patterning of disease has been explored, but they were often ecological in design, used broad census geographic levels, lacked individual-level data, or when available, did not simultaneously analyze community- and individual-level risk factors using appropriate modeling techniques...
May 23, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28535258/invited-commentary-beyond-individuals-area-poverty-and-health-or-the-search-for-an-impactful-epidemiology
#9
Ana V Diez Roux
In this commentary, I reflect on the paper "Poverty and Health: Prospective Evidence From the Alameda County Study" by Haan et al. (Am J Epidemiol. 1987;125(6):989-998), which together with supporting work ushered in a surge of epidemiologic interest in the impact of social contexts on health. I discuss why the paper was influential and how the premise of this type of work influenced theories and methods in epidemiology. The paper is placed in the broader context of the nature of evidence in epidemiology and the ultimate purpose of epidemiologic inquiry...
May 23, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28534189/national-trends-in-bariatric-surgery-2012-2015-demographics-procedure-selection-readmissions-and-cost
#10
Scott Kizy, Cyrus Jahansouz, Michael C Downey, Nathanael Hevelone, Sayeed Ikramuddin, Daniel Leslie
BACKGROUND: Bariatric surgery is widely accepted as the best treatment for obesity and type 2 diabetes mellitus (T2DM). The Roux-en-Y gastric bypass (RYGB) and the sleeve gastrectomy (SG) have become the predominant bariatric procedures in the USA over the last several years, although the most recent trends in selection are unknown. OBJECTIVE: The objective of this study is to assess selection trends, readmission rates, and cost of bariatric procedures in the USA from 2012 to 2015...
May 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28534188/outcomes-of-one-anastomosis-gastric-bypass-in-472-diabetic-patients
#11
Osama Taha, Mahmoud Abdelaal, Mohamed Abozeid, Awny Askalany, Mohamed Alaa
BACKGROUND: The positive impact of Roux-en-Y gastric bypass (RYGB) on metabolic syndrome and glycemic control has been proven in obese patients. One anastomosis gastric bypass (OAGB) is a simple, effective and easy to learn procedure. OAGB provides encouraging results for the treatment of diabetes obese patients, but does it have the ability to be an alternative procedure to RYGB in the treatment of these patients? The aim of this study is to evaluate the outcomes of OAGB on diabetic obese patients at the bariatric centre of our university hospital...
May 22, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28533897/introduction-to-the-special-issue-tree-invasions-towards-a-better-understanding-of-their-complex-evolutionary-dynamics
#12
Heidi Hirsch, David M Richardson, Johannes J Le Roux
Many invasive plants show evidence of trait-based evolutionary change, but these remain largely unexplored for invasive trees. The increasing number of invasive trees and their tremendous impacts worldwide, however, illustrates the urgent need to bridge this knowledge gap to apply efficient management. Consequently, an interdisciplinary workshop, held in 2015 at Stellenbosch University in Stellenbosch, South Africa, brought together international researchers to discuss our understanding of evolutionary dynamics in invasive trees...
May 2017: AoB Plants
https://www.readbyqxmd.com/read/28532499/laparoscopic-roux-en-y-gastric-bypass-versus-laparoscopic-mini-gastric-bypass-in-the-treatment-of-obesity-study-protocol-for-a-randomized-controlled-trial
#13
Marko Kraljević, Tarik Delko, Thomas Köstler, Elena Osto, Thomas Lutz, Sarah Thommen, Raoul A Droeser, Lincoln Rothwell, Daniel Oertli, Urs Zingg
BACKGROUND: Laparoscopic Roux-en-Y gastric bypass (LRYGB) is considered the gold standard in bariatric surgery, achieving durable long-term weight loss with improvement of obesity-related comorbidities. Lately, the laparoscopic mini gastric bypass (LMGB) has gained worldwide popularity with similar results to LRYGB in terms of weight loss and comorbidity resolution. However, there is a lack of randomized controlled trials (RCT) comparing LMGB and LRYGB. This article describes the design and protocol of a randomized controlled trial comparing the outcomes of these two bariatric procedures...
May 22, 2017: Trials
https://www.readbyqxmd.com/read/28530659/actin-cortex-architecture-regulates-cell-surface-tension
#14
Priyamvada Chugh, Andrew G Clark, Matthew B Smith, Davide A D Cassani, Kai Dierkes, Anan Ragab, Philippe P Roux, Guillaume Charras, Guillaume Salbreux, Ewa K Paluch
Animal cell shape is largely determined by the cortex, a thin actin network underlying the plasma membrane in which myosin-driven stresses generate contractile tension. Tension gradients result in local contractions and drive cell deformations. Previous cortical tension regulation studies have focused on myosin motors. Here, we show that cortical actin network architecture is equally important. First, we observe that actin cortex thickness and tension are inversely correlated during cell-cycle progression. We then show that the actin filament length regulators CFL1, CAPZB and DIAPH1 regulate mitotic cortex thickness and find that both increasing and decreasing thickness decreases tension in mitosis...
May 22, 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/28529497/efficacy-and-safety-of-fingolimod-in-daily-practice-experience-of-an-academic-ms-french-center
#15
Thomas Roux, Elisabeth Maillart, Jean-Sébastien Vidal, Sophie Tezenas du Montcel, Catherine Lubetzki, Caroline Papeix
INTRODUCTION: Fingolimod (Fg), a sphingosine 1-phosphate receptor modulator, decreases the annual relapse rate (ARR) in relapsing-remitting multiple sclerosis (RRMS). The aim of this study was to assess the efficacy and safety of Fg in daily practice in patients with RRMS, previously treated with natalizumab (Nz) or not, and systematically followed during at least 1 year. METHODS: Data were collected from the patient files. Primary endpoint was the comparison between the ARR the year before Fg onset and after 1 and 2 years of Fg treatment...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28528115/alcohol-and-other-substance-use-after-bariatric-surgery-prospective-evidence-from-a-u-s-multicenter-cohort-study
#16
Wendy C King, Jia-Yuh Chen, Anita P Courcoulas, Gregory F Dakin, Scott G Engel, David R Flum, Marcelo W Hinojosa, Melissa A Kalarchian, Samer G Mattar, James E Mitchell, Alfons Pomp, Walter J Pories, Kristine J Steffen, Gretchen E White, Bruce M Wolfe, Susan Z Yanovski
BACKGROUND: Empirical evidence suggests Roux-en-Y gastric bypass (RYGB) increases risk of developing alcohol use disorder (AUD). However, prospective assessment of substance use disorders (SUD) after bariatric surgery is limited. OBJECTIVE: To report SUD-related outcomes after RYGB and laparoscopic adjustable gastric banding (LAGB). To identify factors associated with incident SUD-related outcomes. SETTING: 10 U.S. hospitals METHODS: The Longitudinal Assessment of Bariatric Surgery-2 is a prospective cohort study...
March 31, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28528061/real-time-computed-tomography-highlights-pulmonary-parenchymal-evolution-during-ex%C3%A2-vivo-lung-reconditioning
#17
Edouard Sage, Julien De Wolf, Philippe Puyo, Pierre Bonnette, Matthieu Glorion, Nicolas Salley, Antoine Roux, Ngai Liu, Alain Chapelier
Ex vivo lung perfusion (EVLP) has been developed as a method to reassess and recondition marginal lungs. However, evaluation during procedures is limited to a combination of physiologic variables such as gas exchange, pulmonary mechanics, and pulmonary vascular resistance. The aim of this study was to analyze the feasibility of real-time computed tomographic (CT) imaging to improve the evaluation of the lung during EVLP procedures.
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28527155/status-of-laparoscopic-sleeve-gastrectomy-in-china-a-national-survey
#18
Shibo Lin, Wei Guan, Pankaj Hans, Hui Liang
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is a favorable bariatric procedure. This study evaluated the status of LSG in China. METHODS: During the 4(th) International Forum of Bariatric and Metabolic Surgery in May 2016, Nanjing China, an on-the-spot questionnaire was filled out by 105 attending surgeons with experience of LSG. The feedback data was collected and analyzed. RESULTS: For preoperative preparations, surgeons preferred blood glucose control with insulin (61...
May 19, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28526433/risk-of-low-birth-weight-and-micronutrient-deficiencies-in-neonates-from-mothers-after-gastric-bypass-a-case-control-study
#19
Geraldine Gascoin, Maxime Gerard, Agnès Sallé, Guillaume Becouarn, Stephanie Rouleau, Loïc Sentilhes, Régis Coutant
BACKGROUND: An increased risk of small-for-gestational-age infants after maternal bariatric surgery has been shown. The risk of micronutrients deficiencies in these neonates is unclear. OBJECTIVE: To screen for micronutrients deficiencies in newborns of mothers with gastric bypass. SETTINGS: University hospital in Angers, France. METHODS: This study compared the clinical and cord blood biological characteristics of 56 newborns of mothers with prior Roux-en-Y gastric bypass (RYGB) and 56 newborns of nonobese healthy mothers after normal pregnancy (controls), followed between January 3, 2008 and October 31, 2012...
March 27, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28524868/diabetes-associated-microbiota-in-fa-fa-rats-is-modified-by-roux-en-y-gastric-bypass
#20
Tulika Arora, Florian Seyfried, Neil G Docherty, Valentina Tremaroli, Carel W le Roux, Rosie Perkins, Fredrik Bäckhed
Roux-en-Y gastric bypass (RYGB) and duodenal jejunal bypass (DJB), two different forms of bariatric surgery, are associated with improved glucose tolerance, but it is not clear whether the gut microbiota contributes to this effect. Here we used fa/fa rats as a model of impaired glucose tolerance to investigate whether (i) the microbiota varies between fa/fa and nondiabetic fa/+ rats; (ii) the microbiota of fa/fa rats is affected by RYGB and/or DJB; and (iii) surgically induced microbiota alterations contribute to glucose metabolism...
May 19, 2017: ISME Journal
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