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medial frontal negativity

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https://www.readbyqxmd.com/read/28915082/a-combined-study-of-slc6a15-gene-polymorphism-and-the-resting-state-functional-magnetic-resonance-imaging-in-first-episode-drug-naive-major-depressive-disorder
#1
Lijuan Wang, Zhifen Liu, Xiaohua Cao, Jianying Li, Aixia Zhang, Ning Sun, Chunxia Yang, Kerang Zhang
AIMS: The SLC6A15 gene has been identified as a novel candidate gene for major depressive disorder (MDD). However, the mechanism underlying the effects of how the SLC6A15 gene affects functional brain activity of patients with MDD remains unknown. METHODS: In the present study, we investigated the effect of the SLC6A15 gene polymorphism, rs1545843, on resting-state brain function in MDD with the imaging genomic technology and the regional homogeneity (ReHo) method...
September 2017: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/28871288/error-specific-cognitive-control-alterations-in-generalized-anxiety-disorder
#2
James F Cavanagh, Alexandria Meyer, Greg Hajcak
BACKGROUND: Trait anxiety is reliably associated with enhanced neural responses following errors: meta analyses have described how the electrophysiological response to errors known as the Error-Related Negativity (ERN) is increased in anxious individuals, particularly in relation to worry. The ERN has been related to a broader class of control signals, particularly via a common theta band denominator, but it is unknown whether worry relates to these alternative medial frontal metrics...
July 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28856095/localizing-value-of-electrical-source-imaging-frontal-lobe-malformations-of-cortical-development-and-negative-mri-related-epilepsies-are-the-best-candidates
#3
Chifaou Abdallah, Louis G Maillard, Estelle Rikir, Jacques Jonas, Anne Thiriaux, Martine Gavaret, Fabrice Bartolomei, Sophie Colnat-Coulbois, Jean-Pierre Vignal, Laurent Koessler
OBJECTIVE: We aimed to prospectively assess the anatomical concordance of electric source localizations of interictal discharges with the epileptogenic zone (EZ) estimated by stereo-electroencephalography (SEEG) according to different subgroups: the type of epilepsy, the presence of a structural MRI lesion, the aetiology and the depth of the EZ. METHODS: In a prospective multicentric observational study, we enrolled 85 consecutive patients undergoing pre-surgical SEEG investigation for focal drug-resistant epilepsy...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28855654/a-meta-analysis-of-voxel-based-brain-morphometry-studies-in-obstructive-sleep-apnea
#4
Yan Shi, Lizhou Chen, Taolin Chen, Lei Li, Jing Dai, Su Lui, Xiaoqi Huang, John A Sweeney, Qiyong Gong
Gray matter (GM) anomalies may represent a critical pathology underlying obstructive sleep apnea (OSA). However, the evidence regarding their clinical relevance is inconsistent. We conducted a meta-analysis of voxel-based morphometry (VBM) studies of patients with OSA to identify their brain abnormalities. A systematic search was conducted based on PRISMA guidelines, and a meta-analysis was performed using the anisotropic effect-size-based algorithms (ASE-SDM) to quantitatively estimate regional GM changes in patients with OSA...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28845172/balance-deficit-and-brain-connectivity-in-children-with-attention-deficit-hyperactivity-disorder
#5
Sun Mi Kim, Gi Jung Hyun, Tae-Woon Jung, Young Don Son, In-Hee Cho, Baik Seok Kee, Doug Hyun Han
OBJECTIVE: We aimed to assess disturbances in postural and gait balance and functional connectivity within the brain regions controlling balance in children with attention-deficit/hyperactivity disorder (ADHD). METHODS: Thirteen children with ADHD and 13 age- and sex-matched controls were recruited. Gait balance was assessed by the difference in the center of pressure (COP) between the left and right foot, as well as the difference in plantar pressure between the left and right foot during gait...
July 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28763879/-study-of-fraction-amplitude-of-low-frequency-fluctuation-on-resting-state-functional-magnetic-resonance-imaging-in-adultperipheral-facial-paralysis
#6
Y J Zhu, G L Ma, T B Song, L Du, R C Guo, S L Sun, H Li, L G Sun
Objective: To analysis the change of brain functional activity in the left and right peripheral facial paralysis by using resting-state functional magnetic resonance imaging (R-fMRI) of fraction amplitude of low frequency fluctuation(fALFF) measurement technique, and research the abnormal brain region with different side patients whether there are differences. Methods: A total of 43 patients with peripheral facial paralysis patients (patient groups, divided into left / right two subgroups) and 21 healthy volunteers (control group) in this study...
July 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28755988/acute-affective-reactivity-and-quality-of-life-in-older-adults-with-amnestic-mild-cognitive-impairment-a-functional-mri-study
#7
Ping Ren, Kathi L Heffner, Alanna Jacobs, Feng Lin
OBJECTIVES: Poor quality of life (QoL) is a major concern among older adults with amnestic mild cognitive impairment (MCI). Maladaptive affective regulation and its relevant frontal dysfunction that are often observed in older adults with MCI may provide an insight into the understanding of their QoL. METHODS: In this case-controlled study, participants (MCI patients, N = 18; healthy comparisons [HC], N = 21) completed cognitive tasks, and underwent resting-state functional magnetic resonance imaging (rs-fMRI) immediately before and after the tasks...
June 27, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28740390/brain-regions-associated-with-anosognosia-for-memory-disturbance-in-alzheimer-s-disease-a-magnetic-resonance-imaging-study
#8
Hiroshi Fujimoto, Teruyuki Matsuoka, Yuka Kato, Keisuke Shibata, Kaeko Nakamura, Kei Yamada, Jin Narumoto
BACKGROUND AND OBJECTIVE: Patients with Alzheimer's disease (AD) are frequently unaware of their cognitive symptoms and medical diagnosis. The term "anosognosia" is used to indicate a general lack of awareness of one's disease or disorder. The neural substrate underlying anosognosia in AD is unclear. Since anosognosia for memory disturbance might be an initial sign of AD, it is important to determine the neural correlates. This study was designed to investigate the characteristics and neural correlates of anosognosia for memory disturbance in patients with mild AD...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28736888/alterations-in-cortical-thickness-in-nonmedicated-premature-ejaculation-patients-a-morphometric-mri-study
#9
Fan Guo, Yi-Bin Xi, Ming Gao, Lin Liu, Ning-Bo Fei, Wei Qin, Chen Li, Long-Biao Cui, Fei Yan, Lei Yu, Jian-Lin Yuan, Hong Yin
PURPOSE: Premature ejaculation (PE) is one of the most common sexual dysfunctions in men. However, there has been little research evaluating alterations in brain structure related to PE. We aimed to investigate the characteristics of nonmedicated PE patients in terms of brain morphometry. MATERIALS AND METHODS: The sample consisted with 32 medication-naïve adult men with clinical diagnosed PE and matched 31 healthy controls. All participants received diagnostic interviews and 3...
July 24, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28729935/single-trial-eeg-informed-fmri-analysis-of-emotional-decision-problems-in-hot-executive-function
#10
Qian Guo, Tiantong Zhou, Wenjie Li, Li Dong, Suhong Wang, Ling Zou
BACKGROUND: Executive function refers to conscious control in psychological process which relates to thinking and action. Emotional decision is a part of hot executive function and contains emotion and logic elements. As a kind of important social adaptation ability, more and more attention has been paid in recent years. OBJECTIVE: Gambling task can be well performed in the study of emotional decision. As fMRI researches focused on gambling task show not completely consistent brain activation regions, this study adopted EEG-fMRI fusion technology to reveal brain neural activity related with feedback stimuli...
July 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28721052/study-of-the-combinatorial-impact-of-empathy-and-emotion-on-the-processing-of-conflicts-of-interest-with-the-event-related-potential-technique
#11
Xiaoli He, Ni Zhang
OBJECTIVES: Studies have found that empathy is important in moral development and violence suppression, and emotion also affects empathy. However, the combinatorial effect of emotion and empathy on the processing of conflicts is not known. MATERIALS AND METHODS: A total of 44 undergraduate students (23 in low-empathy group and 21 in high-empathy group) were enrolled in this study. They were subjected to positive, negative, and neutral emotion evoking, as well as conflicting or nonconflicting proposals...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28713328/recovery-from-unrecognized-sleep-loss-accumulated-in-daily-life-improved-mood-regulation-via-prefrontal-suppression-of-amygdala-activity
#12
Yuki Motomura, Shingo Kitamura, Kyoko Nakazaki, Kentaro Oba, Ruri Katsunuma, Yuri Terasawa, Akiko Hida, Yoshiya Moriguchi, Kazuo Mishima
Many modern people suffer from sleep debt that has accumulated in everyday life but is not subjectively noticed [potential sleep debt (PSD)]. Our hypothesis for this study was that resolution of PSD through sleep extension optimizes mood regulation by altering the functional connectivity between the amygdala and prefrontal cortex. Fifteen healthy male participants underwent an experiment consisting of a baseline (BL) evaluation followed by two successive interventions, namely, a 9-day sleep extension followed by one night of total sleep deprivation (TSD)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28621460/older-adults-display-diminished-error-processing-and-response-in-a-continuous-tracking-task
#13
Francisco L Colino, Harvey Howse, Angela Norton, Robert Trska, Anthony Pluta, Stephen J C Luehr, Todd C Handy, Olave E Krigolson
Advancing age is often accompanied by a decline in motor control that results in a decreased ability to successfully perform motor tasks. While there are multiple factors that contribute to age-related deficits in motor control, one unexplored possibility is that age-related deficits in our ability to evaluate motor output result in an increase in motor errors. In line with this, previous work from our laboratory demonstrated that motor errors evoked an error-related negativity (ERN)-a component of the human ERP associated with error evaluation originating within the human medial-frontal cortex...
June 16, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28606629/neural-substrates-underlying-balanced-time-perspective-a-combined-voxel-based-morphometry-and-resting-state-functional-connectivity-study
#14
Yiqun Guo, Zhiyi Chen, Tingyong Feng
Balanced time perspective (BTP), which is defined as a mental ability to switch flexibly among different time perspectives Zimbardo and Boyd (1999), has been suggested to be a central component of positive psychology Boniwell and Zimbardo (2004). BTP reflects individual's cognitive flexibility towards different time frames, which leads to many positive outcomes, including positive mood, subjective wellbeing, emotional intelligence, fluid intelligence, and executive control. However, the neural basis of BTP is still unclear...
June 9, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28601965/event-related-potentials-reflect-impaired-temporal-interval-learning-following-haloperidol-administration
#15
Sarah E Forster, Patrick Zirnheld, Anantha Shekhar, Stuart R Steinhauer, Brian F O'Donnell, William P Hetrick
BACKGROUND: Signals carried by the mesencephalic dopamine system and conveyed to anterior cingulate cortex are critically implicated in probabilistic reward learning and performance monitoring. A common evaluative mechanism purportedly subserves both functions, giving rise to homologous medial frontal negativities in feedback- and response-locked event-related brain potentials (the feedback-related negativity (FRN) and the error-related negativity (ERN), respectively), reflecting dopamine-dependent prediction error signals to unexpectedly negative events...
June 10, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28596726/ability-to-gain-control-over-one-s-own-brain-activity-and-its-relation-to-spiritual-practice-a-multimodal-imaging-study
#16
Silvia E Kober, Matthias Witte, Manuel Ninaus, Karl Koschutnig, Daniel Wiesen, Gabriela Zaiser, Christa Neuper, Guilherme Wood
Spiritual practice, such as prayer or meditation, is associated with focusing attention on internal states and self-awareness processes. As these cognitive control mechanisms presumably are also important for neurofeedback (NF), we investigated whether people who pray frequently (N = 20) show a higher ability of self-control over their own brain activity compared to a control group of individuals who rarely pray (N = 20). All participants underwent structural magnetic resonance imaging (MRI) and one session of sensorimotor rhythm (SMR, 12-15 Hz) based NF training...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28588480/reduced-gray-matter-volume-in-patients-with-type-2-diabetes-mellitus
#17
Jia Liu, Taiyuan Liu, Wenhui Wang, Lun Ma, Xiaoyue Ma, Shaojie Shi, Qiyong Gong, Meiyun Wang
Background and Purpose: Previous studies of voxel-based morphometry (VBM) have found that patients with type 2 diabetes mellitus (T2DM) exhibit gray matter alterations, but these findings are inconsistent and have not been quantitatively reviewed. Therefore, the aim of this study was to conduct a quantitative meta-analysis of VBM studies of patients with T2DM. Materials and Methods: The seed-based d mapping method was applied to quantitatively estimate the regional gray matter abnormalities in T2DM patients...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28567171/a-functional-mri-based-model-for-individual-memory-assessment-in-patients-eligible-for-anterior-temporal-lobe-resection
#18
Maria Strandberg, Peter Mannfolk, Lars Stenberg, Hanna Ljung, Ia Rorsman, Elna-Marie Larsson, Danielle van Westen, Kristina Källén
TITLE: A functional (f) MRI-based model for individual memory assessment in patients eligible for temporal lobe resection. AIM: To investigate if pre-operative fMRI memory paradigms, add predictive information with regard to post-surgical memory deficits. METHODS: Fourteen pharmacoresistant Temporal Lobe Epilepsy (TLE) patients accepted for Anterior Temporal Lobe Resection (ATLR) were included. A clinical risk assessment score (RAS 0-3) was constructed from structural MRI, neuropsychological testing and hemisphere dominance...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28558941/effects-of-aripiprazole-versus-risperidone-on-brain-activation-during-planning-and-social-emotional-evaluation-in-schizophrenia-a-single-blind-randomized-exploratory-study
#19
Edith J Liemburg, Frank van Es, Henderikus Knegtering, André Aleman
Impaired function of prefrontal brain networks may be the source of both negative symptoms and neurocognitive problems in psychotic disorders. Whereas most antipsychotics may decrease prefrontal activation, the partial dopamine D2-receptor agonist aripiprazole is hypothesized to improve prefrontal function. This study investigated whether patients with a psychotic disorder would show stronger activation of prefrontal areas and associated regions after treatment with aripiprazole compared to risperidone treatment...
May 27, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28556905/working-memory-load-impairs-the-evaluation-of-behavioral-errors-in-the-medial-frontal-cortex
#20
Martin E Maier, Marco Steinhauser
Early error monitoring in the medial frontal cortex enables error detection and the evaluation of error significance, which helps prioritize adaptive control. This ability has been assumed to be independent from central capacity, a limited pool of resources assumed to be involved in cognitive control. The present study investigated whether error evaluation depends on central capacity by measuring the error-related negativity (Ne/ERN) in a flanker paradigm while working memory load was varied on two levels. We used a four-choice flanker paradigm in which participants had to classify targets while ignoring flankers...
May 30, 2017: Psychophysiology
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