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error-related negativity

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https://www.readbyqxmd.com/read/27911420/-role-of-immunological-factors-in-the-development-of-myopic-choroidal-neovascularization
#1
A G Shchuko, N V Zaitseva, T N Yur'eva, E R Chernykh, I M Mikhalevich, A V Grigor'eva
AIM: To study the concentration of cytokines in the aqueous humor of the anterior chamber in patients with myopic choroidal neovascularization (mCNV) and to compare the results to their ophthalmic status. MATERIAL AND METHODS: A total of 19 patients (19 eyes) with mCNV treated with intravitreal ranibizumab were included in the study. The control group consisted of 15 patients (15 eyes) with myopia who had cataract surgery. Age, sex, and refractive error distribution were similar to that in the study group...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27898304/motivational-processes-from-expectancy-value-theory-are-associated-with-variability-in-the-error-positivity-in-young-children
#2
Matthew H Kim, Loren M Marulis, Jennie K Grammer, Frederick J Morrison, William J Gehring
Motivational beliefs and values influence how children approach challenging activities. The current study explored motivational processes from an expectancy-value theory framework by studying children's mistakes and their responses to them by focusing on two event-related potential (ERP) components: the error-related negativity (ERN) and the error positivity (Pe). Motivation was assessed using a child-friendly challenge puzzle task and a brief interview measure prior to ERP testing. Data from 50 4- to 6-year-old children revealed that greater perceived competence beliefs were related to a larger Pe, whereas stronger intrinsic task value beliefs were associated with a smaller Pe...
November 26, 2016: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/27897675/mediofrontal-negativity-signals-unexpected-timing-of-salient-outcomes
#3
Sara Garofalo, Christopher Timmermann, Simone Battaglia, Martin E Maier, Giuseppe di Pellegrino
The medial pFC (mPFC) and ACC have been consistently implicated in learning predictions of future outcomes and signaling prediction errors (i.e., unexpected deviations from such predictions). A computational model of ACC/mPFC posits that these prediction errors should be modulated by outcomes occurring at unexpected times, even if the outcomes themselves are predicted. However, unexpectedness per se is not the only variable that modulates ACC/mPFC activity, as studies reported its sensitivity to the salience of outcomes...
November 29, 2016: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/27896144/clinical-decision-support-for-drug-related-events-moving-towards-better-prevention
#4
REVIEW
Sandra L Kane-Gill, Archita Achanta, John A Kellum, Steven M Handler
Clinical decision support (CDS) systems with automated alerts integrated into electronic medical records demonstrate efficacy for detecting medication errors (ME) and adverse drug events (ADEs). Critically ill patients are at increased risk for ME, ADEs and serious negative outcomes related to these events. Capitalizing on CDS to detect ME and prevent adverse drug related events has the potential to improve patient outcomes. The key to an effective medication safety surveillance system incorporating CDS is advancing the signals for alerts by using trajectory analyses to predict clinical events, instead of waiting for these events to occur...
November 4, 2016: World Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27891556/comparing-self-regulation-associated-event-related-potentials-in-preschool-children-with-and-without-high-levels-of-disruptive-behavior
#5
Adam S Grabell, Sheryl L Olson, Twila Tardif, Meaghan C Thompson, William J Gehring
Deficient self-regulation plays a key role in the etiology of early onset disruptive behavior disorders and signals risk for chronic psychopathology. However, to date, there has been no research comparing preschool children with and without high levels of disruptive behavior using Event Related Potentials (ERPs) associated with specific self-regulation sub-processes. We examined 15 preschool children with high levels of disruptive behavior (35 % female) and 20 peers with low disruptive behavior (50 % female) who completed a Go/No-go task that provided emotionally valenced feedback...
November 28, 2016: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/27888168/estimating-the-duration-of-public-concern-after-the-fukushima-dai-ichi-nuclear-power-station-accident-from-the-occurrence-of-radiation-exposure-related-terms-on-twitter-a-retrospective-data-analysis
#6
Naoki Nishimoto, Mizuki Ota, Ayako Yagahara, Katsuhiko Ogasawara
BACKGROUND: After the Fukushima Dai-ichi Nuclear Power Station accident in Japan on March 11, 2011, a large number of comments, both positive and negative, were posted on social media. OBJECTIVE: The objective of this study was to clarify the characteristics of the trend in the number of tweets posted on Twitter, and to estimate how long public concern regarding the accident continued. We surveyed the attenuation period of the first term occurrence related to radiation exposure as a surrogate endpoint for the duration of concern...
November 25, 2016: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/27884804/gender-based-differences-in-surgical-residents-perceptions-of-patient-safety-continuity-of-care-and-well-being-an-analysis-from-the-flexibility-in-duty-hour-requirements-for-surgical-trainees-first-trial
#7
Kristen A Ban, Jeanette W Chung, Richard S Matulewicz, Rachel R Kelz, Judy A Shea, Allison R Dahlke, Christopher Quinn, Anthony D Yang, Karl Y Bilimoria
BACKGROUND: Little is known about gender differences in residency training experiences and whether duty hour policies affect these differences. Using data from the Flexibility in Duty Hour Requirements for Surgical Trainees (FIRST) Trial, we (1) examined gender differences in surgical resident perceptions of patient safety, education, health/well-being, and job satisfaction and (2) assessed whether duty hour policies affected gender differences. STUDY DESIGN: We compared proportions of male and female residents expressing dissatisfaction or perceiving a negative effect of duty hours on aspects of residency training (patient safety, resident education, well-being, job satisfaction) overall and by postgraduate year (PGY)...
November 8, 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27870417/gender-differences-in-neural-correlates-of-stress-induced-anxiety
#8
Dongju Seo, Aneesha Ahluwalia, Marc N Potenza, Rajita Sinha
Although gender differences have been identified as a crucial factor for understanding stress-related anxiety and associated clinical disorders, the neural mechanisms underlying these differences remain unclear. To explore gender differences in the neural correlates of stress-induced anxiety, the current study used functional magnetic resonance imaging to examine brain responses in 96 healthy men and women with commensurable levels of trait anxiety as they engaged in a personalized guided imagery paradigm to provoke stress and neutral-relaxing experiences...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27869058/relationship-of-amotivation-to-neurocognition-self-efficacy-and-functioning-in-first-episode-psychosis-a-structural-equation-modeling-approach
#9
W C Chang, V W Y Kwong, C L M Hui, S K W Chan, E H M Lee, E Y H Chen
BACKGROUND: Better understanding of the complex interplay among key determinants of functional outcome is crucial to promoting recovery in psychotic disorders. However, this is understudied in the early course of illness. We aimed to examine the relationships among negative symptoms, neurocognition, general self-efficacy and global functioning in first-episode psychosis (FEP) patients using structural equation modeling (SEM). METHOD: Three hundred and twenty-one Chinese patients aged 26-55 years presenting with FEP to an early intervention program in Hong Kong were recruited...
November 21, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27867079/variability-in-diagnostic-error-rates-of-ten-mri-centers-performing-lumbar-spine-mri-exams-on-the-same-patient-within-a-three-week-period
#10
Richard Herzog, Daniel R Elgort, Adam E Flanders, Peter J Moley
BACKGROUND CONTEXT: In today's healthcare climate, Magnetic Resonance Imaging (MRI) is often perceived as a commodity - a service where there are no meaningful differences in quality and thus an area in which patients can be advised to select a provider based on price and convenience alone. If this prevailing view is correct, then a patient should expect to receive the same radiological diagnosis regardless of which imaging center he or she visits or which radiologist reviews the examination...
November 17, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27865113/implicit-moral-evaluations-a-multinomial-modeling-approach
#11
C Daryl Cameron, B Keith Payne, Walter Sinnott-Armstrong, Julian A Scheffer, Michael Inzlicht
Implicit moral evaluations-i.e., immediate, unintentional assessments of the wrongness of actions or persons-play a central role in supporting moral behavior in everyday life. Yet little research has employed methods that rigorously measure individual differences in implicit moral evaluations. In five experiments, we develop a new sequential priming measure-the Moral Categorization Task-and a multinomial model that decomposes judgment on this task into multiple component processes. These include implicit moral evaluations of moral transgression primes (Unintentional Judgment), accurate moral judgments about target actions (Intentional Judgment), and a directional tendency to judge actions as morally wrong (Response Bias)...
November 16, 2016: Cognition
https://www.readbyqxmd.com/read/27864029/time-frequency-phase-synchrony-approaches-with-erps
#12
Selin Aviyente, Anne Tootell, Edward M Bernat
Time-frequency signal processing approaches are well-developed, and have been widely employed for the study of the energy distribution of event-related potential (ERP) data across time and frequency. Wavelet time-frequency transform (TFT) and Cohen's class of time-frequency distributions (TFD) are the most widely used in the field. While ERP TFT approaches have been most extensively developed for amplitude measures, reflecting the magnitude of regional neuronal activity, time-frequency phase-synchrony measures have gained increased utility in recent years for the assessment of functional connectivity...
November 15, 2016: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/27858934/contrast-sensitivity-and-its-determinants-in-people-with-diabetes-sn-dreams-ii-report-no-6
#13
L Gella, R Raman, S S Pal, S Ganesan, T Sharma
PurposeTo assess contrast sensitivity (CS) and to elucidate the factors associated with CS among subjects with type 2 diabetes in a cross-sectional population-based study.Patients and MethodsSubjects were recruited from a follow-up cohort, Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular genetics Study (SN-DREAMS II). Of 958 subjects who were followed up in SN-DREAMS II, a subset of 653 subjects was included in the analysis. All subjects underwent a comprehensive eye examination, which included CS assessment using the Pelli-Robson chart...
November 18, 2016: Eye
https://www.readbyqxmd.com/read/27849004/performance-error-related-activity-in-monkey-striatum-during-social-interactions
#14
Raymundo Báez-Mendoza, Wolfram Schultz
Monitoring our performance is fundamental to motor control while monitoring other's performance is fundamental to social coordination. The striatum is hypothesized to play a role in action selection, action initiation, and action parsing, but we know little of its role in performance monitoring. Furthermore, the striatum contains neurons that respond to own and other's actions. Therefore, we asked if striatal neurons signal own and conspecific's performance errors. Two macaque monkeys sitting across a touch-sensitive table in plain view of each other took turns performing a simple motor task to obtain juice rewards while we recorded single striatal neurons from one monkey at a time...
November 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27835807/acute-stress-impairs-frontocingulate-activation-during-error-monitoring-in-remitted-depression
#15
Alexis E Whitton, Ashlee Van't Veer, Pragya Kakani, Daniel G Dillon, Manon L Ironside, Anja Haile, David J Crowley, Diego A Pizzagalli
Deficits in cognitive control are a hallmark characteristic of depression, however less is known about the degree to which they persist beyond symptom remission and might contribute to symptom recurrence in remitted individuals (rMDD). Evidence indicates that stress interferes with cognitive control, highlighting a potential mechanism by which stress precipitates depression relapse. Therefore, this study examined whether stress exposure elicits deficits in error monitoring - a component of cognitive control thought to be particularly implicated in the ability to adaptively respond to negative feedback - in individuals with rMDD...
January 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27833939/probabilistic-reinforcement-learning-in-patients-with-schizophrenia-relationships-to-anhedonia-and-avolition
#16
Erin C Dowd, Michael J Frank, Anne Collins, James M Gold, Deanna M Barch
BACKGROUND: Anhedonia (a reduced experience of pleasure) and avolition (a reduction in goal-directed activity) are common features of schizophrenia that have substantial effects on functional outcome, but are poorly understood and treated. Here, we examined whether alterations in reinforcement learning may contribute to these symptoms in schizophrenia by impairing the translation of reward information into goal-directed action. METHODS: 38 stable outpatients with schizophrenia or schizoaffective disorder and 37 healthy controls underwent fMRI during a probabilistic stimulus selection reinforcement learning task with dissociated choice- and feedback-related activation, followed by a behavioral transfer task allowing separate assessment of learning from positive versus negative outcomes...
September 2016: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/27825339/improvement-of-alkalophilicity-of-an-alkaline-xylanase-xyn11a-lc-from-bacillus-sp-sn5-by-random-mutation-and-glu135-saturation-mutagenesis
#17
Wenqin Bai, Yufan Cao, Jun Liu, Qinhong Wang, Zhenhu Jia
BACKGROUND: Family 11 alkaline xylanases have great potential economic applications in the pulp and paper industry. In this study, we would improve the alkalophilicity of family 11 alkaline xylanase Xyn11A-LC from Bacillus sp. SN5, for the better application in this field. RESULTS: A random mutation library of Xyn11A-LC with about 10,000 clones was constructed by error-prone PCR. One mutant, M52-C10 (V116A and E135V), with improved alkalophilicity was obtained from the library...
November 8, 2016: BMC Biotechnology
https://www.readbyqxmd.com/read/27824757/circulating-cell-free-dna-to-determine-the-fetal-rhd-status-in-all-three-trimesters-of-pregnancy
#18
Kenneth J Moise, Manisha Gandhi, Noemi H Boring, Richard OʼShaughnessy, Lynn L Simpson, Honor M Wolfe, Jason K Baxter, William Polzin, Keith A Eddleman, Sonia S Hassan, Daniel W Skupski, Greg Ryan, Martin Walker, Garrett Lam, Richard Brown, M Amanda Skoll, Christopher Robinson, Asad Sheikh, Richard Bronsteen, Lauren A Plante, Graham McLennan, Anna Chikova, Toni Paladino
OBJECTIVE: To estimate the accuracy of a new assay to determine the fetal RHD status using circulating cell-free DNA. METHODS: This was a prospective, observational study. Maternal blood samples were collected in each trimester of pregnancy in 520 nonalloimmunized RhD-negative patients. Plasma samples were analyzed for circulating cell-free DNA using the SensiGENE RHD test, which used primers for exons 4 and 7 as previously described and incorporated a new primer design for exon 5 of the RHD gene...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27822182/dopaminergic-medication-modulates-learning-from-feedback-and-error-related-negativity-in-parkinson-s-disease-a-pilot-study
#19
Chiara Volpato, Sami Schiff, Silvia Facchini, Stefano Silvoni, Marianna Cavinato, Francesco Piccione, Angelo Antonini, Niels Birbaumer
Dopamine systems mediate key aspects of reward learning. Parkinson's disease (PD) represents a valuable model to study reward mechanisms because both the disease process and the anti-Parkinson medications influence dopamine neurotransmission. The aim of this pilot study was to investigate whether the level of levodopa differently modulates learning from positive and negative feedback and its electrophysiological correlate, the error related negativity (ERN), in PD. Ten PD patients and ten healthy participants performed a two-stage reinforcement learning task...
2016: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/27819467/external-validity-of-a-hierarchical-dimensional-model-of-child-and-adolescent-psychopathology-tests-using-confirmatory-factor-analyses-and-multivariate-behavior-genetic-analyses
#20
Irwin D Waldman, Holly E Poore, Carol van Hulle, Paul J Rathouz, Benjamin B Lahey
Several recent studies of the hierarchical phenotypic structure of psychopathology have identified a General psychopathology factor in addition to the more expected specific Externalizing and Internalizing dimensions in both youth and adult samples and some have found relevant unique external correlates of this General factor. We used data from 1,568 twin pairs (599 MZ & 969 DZ) age 9 to 17 to test hypotheses for the underlying structure of youth psychopathology and the external validity of the higher-order factors...
November 2016: Journal of Abnormal Psychology
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