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https://www.readbyqxmd.com/read/28549796/development-of-the-error-monitoring-system-from-ages-9-35-unique-insight-provided-by-mri-constrained-source-localization-of-eeg
#1
George A Buzzell, John E Richards, Lauren K White, Tyson V Barker, Daniel S Pine, Nathan A Fox
The ability to self-detect errors and dynamically adapt behavior is a cornerstone of higher-level cognition, requiring coordinated activity from a network of neural regions. However, disagreement exists over how the error-monitoring system develops throughout adolescence and early adulthood. The present report leveraged MRI-constrained EEG source localization to detail typical development of the error-monitoring system in a sample of 9-35 year-olds (n=43). Participants performed a flanker task while high-density EEG was recorded; structural MRIs were also acquired for all participants...
May 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/28548052/optimizing-the-stimulus-presentation-paradigm-design-for-the-p300-based-brain-computer-interface-using-performance-prediction
#2
Boyla Mainsah, Galen Reeves, Leslie Collins, Chandra Throckmorton
<i>Objective:</i> The role of a brain-computer interface (BCI) is to discern a user's intended message by extracting and decoding relevant information from brain signals. Stimulus-driven BCIs, such as the P300 speller, rely on detecting event-related potentials (ERPs) in response to a user attending to relevant or target stimulus events. However, this process is error-prone because the ERPs are embedded in noisy electroencephalography (EEG) data, representing a fundamental problem in communication of the uncertainty in the information that is received during noisy transmission...
May 26, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28546890/near-field-surface-plasmon-field-enhancement-induced-by-rippled-surfaces
#3
Mario D'Acunto, Francesco Fuso, Ruggero Micheletto, Makoto Naruse, Francesco Tantussi, Maria Allegrini
The occurrence of plasmon resonances on metallic nanometer-scale structures is an intrinsically nanoscale phenomenon, given that the two resonance conditions (i.e., negative dielectric permittivity and large free-space wavelength in comparison with system dimensions) are realized at the same time on the nanoscale. Resonances on surface metallic nanostructures are often experimentally found by probing the structures under investigation with radiation of various frequencies following a trial-and-error method...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28546689/risks-of-cefuroxime-prophylaxis-for-postcataract-endophthalmitis
#4
Khaled A Al-Abduljabbar, Donald U Stone
BACKGROUND: Endophthalmitis after cataract surgery is a rare but vision-threatening complication. Intracameral cefuroxime (ICC) has been reported to be effective at reducing the risk, but concerns regarding the risks associated with this intervention remain. METHODS: Systematic review and synthesis of the literature on ICC, with a focus on the risks of therapy. RESULTS: Level 2a evidence was found to support the use of cefuroxime in penicillin-allergic patients...
January 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28544351/the-impact-of-interruptions-on-medication-errors-in-hospitals-an-observational-study-of-nurses
#5
Maree Johnson, Paula Sanchez, Rachel Langdon, Elizabeth Manias, Tracy Levett-Jones, Gabrielle Weidemann, Vicki Aguilar, Bronwyn Everett
AIM: To explore interruptions during medication preparation and administration and their consequences. BACKGROUND: Although not all interruptions in nursing have a negative impact, interruptions during medication rounds have been associated with medication errors. METHOD: A non-participant observational study was undertaken of nurses conducting medication rounds. RESULTS: Fifty-six medication events (including 101 interruptions) were observed...
May 22, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28538704/climate-change-and-its-impact-on-the-yield-of-major-food-crops-evidence-from-pakistan
#6
Sajjad Ali, Ying Liu, Muhammad Ishaq, Tariq Shah, Abdullah, Aasir Ilyas, Izhar Ud Din
Pakistan is vulnerable to climate change, and extreme climatic conditions are threatening food security. This study examines the effects of climate change (e.g., maximum temperature, minimum temperature, rainfall, relative humidity, and the sunshine) on the major crops of Pakistan (e.g., wheat, rice, maize, and sugarcane). The methods of feasible generalized least square (FGLS) and heteroscedasticity and autocorrelation (HAC) consistent standard error were employed using time series data for the period 1989 to 2015...
May 24, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28530410/correction-to-kujawa-proudfit-and-klein-2014
#7
(no author information available yet)
Reports an error in "Neural reactivity to rewards and losses in offspring of mothers and fathers with histories of depressive and anxiety disorders" by Autumn Kujawa, Greg Hajcak Proudfit and Daniel N. Klein (Journal of Abnormal Psychology, 2014[May], Vol 123[2], 287-297). In the original article, there was an error in the Measures section. The article stated that the EEG data were band-pass filtered with cutoffs of 0.1 and 30 Hz and baseline corrected using the 200 ms interval prior to feedback. Instead, the data were actually filtered with cutoffs of 0...
May 22, 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28526931/reduced-amygdala-reactivity-and-impaired-working-memory-during-dissociation-in-borderline-personality-disorder
#8
Annegret Krause-Utz, Dorina Winter, Friederike Schriner, Chui-De Chiu, Stefanie Lis, Philip Spinhoven, Martin Bohus, Christian Schmahl, Bernet M Elzinga
Affective hyper-reactivity and impaired cognitive control of emotional material are core features of borderline personality disorder (BPD). A high percentage of individuals with BPD experience stress-related dissociation, including emotional numbing and memory disruptions. So far little is known about how dissociation influences the neural processing of emotional material in the context of a working memory task in BPD. We aimed to investigate whole-brain activity and amygdala functional connectivity (FC) during an Emotional Working Memory Task (EWMT) after dissociation induction in un-medicated BPD patients compared to healthy controls (HC)...
May 19, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28524133/-wavefront-aberrations-and-accommodation-in-myopes-and-hyperopes
#9
V V Neroev, E P Tarutta, S G Arutyunyan, A T Khandzhyan, N V Khodzhabekyan
AIM: to comparatively investigate accommodation, pseudoaccommodation, and higher-order aberrations in children and young adults with myopia and hyperopia. MATERIAL AND METHODS: A total of 39 myopic (the mean error of (-)5.2±1.5 diopters) and 53 hyperopic (the mean error of (+)3.1±1.15 diopters) eyes of 46 patients aged 5-20 years (11.6±0.6 years on average) were enrolled. Examination included evaluation of the objective accommodative response, relative accommodation reserves, pseudoaccommodation volume (calculated as the difference between the (+)3...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28521603/in-silico-binding-mechanism-prediction-of-benzimidazole-based-corticotropin-releasing-factor-1-receptor-antagonists-by-quantitative-structure-activity-relationship-molecular-docking-and-pharmacokinetic-parameters-calculation
#10
Neeraj Kumar, Shashank Shekhar Mishra, Chandra Shekhar Sharma, Hamendra Pratap Singh, Sourav Kalra
Despite the various research efforts towards the treatment of stress related disorders, the drug has not yet launched last 20 years. Corticotropin releasing factor-1 receptor antagonists have been point of great interest in stress related disorders. In the present study, we have selected benzazole scaffold based compounds as corticotropin releasing factor-1 antagonists and performed 2D and 3D QSAR studies to identify the structural features to elucidating the binding mechanism prediction. The best 2D QSAR model was obtained through multiple linear regression method with r(2) value of 0...
May 19, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28521155/is-laughter-a-better-vocal-change-detector-than-a-growl
#11
Ana P Pinheiro, Carla Barros, Margarida Vasconcelos, Christian Obermeier, Sonja A Kotz
The capacity to predict what should happen next and to minimize any discrepancy between an expected and an actual sensory input (prediction error) is a central aspect of perception. Particularly in vocal communication, the effective prediction of an auditory input that informs the listener about the emotionality of a speaker is critical. What is currently unknown is how the perceived valence of an emotional vocalization affects the capacity to predict and detect a change in the auditory input. This question was probed in a combined event-related potential (ERP) and time-frequency analysis approach...
April 11, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28516227/impairment-in-mismatch-negativity-but-not-repetition-suppression-in-schizophrenia
#12
Brian A Coffman, Sarah M Haigh, Tim K Murphy, Dean F Salisbury
Schizophrenia is characterized by impaired auditory-evoked potentials (AEPs), mismatch negativity (MMN), and sensory gating of AEPs to repeated stimuli (repetition suppression, RS). In the predictive modeling framework, MMN and RS reflect encoding of prediction error and model sharpening, respectively. We compared P50, N100, P200 RS, and pitch and duration MMN in 26 participants diagnosed with schizophrenia (SZ) and 26 matched healthy controls (HC), and assessed relationships between MMN, RS, and SZ diagnosis...
May 17, 2017: Brain Topography
https://www.readbyqxmd.com/read/28510495/fatigue-in-younger-and-older-drivers-effectiveness-of-an-alertness-maintaining-task
#13
Woojin Song, Fu L Woon, Alice Doong, Carol Persad, Louis Tijerina, Pooja Pandit, Carol Cline, Bruno Giordani
OBJECTIVE: The aim of this study was to examine the effects of an alertness maintaining task (AMT) in older, fatigued drivers. BACKGROUND: Fatigue during driving increases crash risk, and previous research suggests that alertness and driving in younger adults may be improved using a secondary AMT during boring, fatigue-eliciting drives. However, the potential impact of an AMT on driving has not been investigated in older drivers whose ability to complete dual tasks has been shown to decline and therefore may be negatively affected with an AMT in driving...
May 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28507528/cognitive-impairments-in-occupational-burnout-error-processing-and-its-indices-of-reactive-and-proactive-control
#14
Krystyna Golonka, Justyna Mojsa-Kaja, Magda Gawlowska, Katarzyna Popiel
The presented study refers to cognitive aspects of burnout as the effects of long-term work-related stress. The purpose of the study was to investigate electrophysiological correlates of burnout to explain the mechanisms of the core burnout symptoms: exhaustion and depersonalization/cynicism. The analyzed error-related electrophysiological markers shed light on impaired cognitive mechanisms and the specific changes in information-processing in burnout. In the EEG study design (N = 80), two components of error-related potential (ERP), error-related negativity (ERN), and error positivity (Pe), were analyzed...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28505151/mixture-models-reveal-multiple-positional-bias-types-in-rna-seq-data-and-lead-to-accurate-transcript-concentration-estimates
#15
Andreas Tuerk, Gregor Wiktorin, Serhat Güler
Accuracy of transcript quantification with RNA-Seq is negatively affected by positional fragment bias. This article introduces Mix2 (rd. "mixquare"), a transcript quantification method which uses a mixture of probability distributions to model and thereby neutralize the effects of positional fragment bias. The parameters of Mix2 are trained by Expectation Maximization resulting in simultaneous transcript abundance and bias estimates. We compare Mix2 to Cufflinks, RSEM, eXpress and PennSeq; state-of-the-art quantification methods implementing some form of bias correction...
May 15, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28503454/quantitative-assessment-of-proprioception-using-dynamometer-in-incomplete-spinal-cord-injury-patients-a-preliminary-study
#16
Won Kee Chang, Yun Suk Jung, Mi-Kyoung Oh, Keewon Kim
OBJECTIVE: To investigate the feasibility of a knee proprioception evaluation using a dynamometer as a tool for evaluating proprioception of the lower extremities in patients with incomplete spinal cord injury (SCI), and to explore its usefulness in predicting the ambulatory outcome. METHODS: A total of 14 SCI patients (10 tetraplegic, 4 paraplegic; all AIS D) were included in this study. The passive repositioning error (PRE) and active repositioning error (ARE) were measured with a dynamometer, along with tibial somatosensory evoked potential (SSEP) and abductor hallucis motor-evoked potential (MEP)...
April 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28499839/does-emotion-change-auditory-prediction-and-deviance-detection
#17
Ana P Pinheiro, Carla Barros, Marcelo Dias, Margaret Niznikiewicz
In the last decades, a growing number of studies provided compelling evidence supporting the interplay of cognitive and affective processes. However, it remains to be clarified whether and how an emotional context affects the prediction and detection of change in unattended sensory events. In an event-related potential (ERP) study, we probed the modulatory role of pleasant, unpleasant and neutral visual contexts on the brain response to automatic detection of change in spectral (intensity) vs. temporal (duration) sound features...
May 9, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28494820/positive-and-negative-consequences-of-making-coffee-among-breakfast-related-irrelevant-objects-evidence-from-mci-dementia-and-healthy-ageing
#18
María Rodríguez-Bailón, Tamara García-Morán, Nuria Montoro-Membila, Estrella Ródenas-García, Marisa Arnedo Montoro, María Jesús Funes Molina
OBJECTIVES: Previous studies have reported impairments in activities of daily living (ADL) performance in the presence of irrelevant but physically/functionally related objects in dementia patients. The aim of the present study was to increase our knowledge about the impact of the presence of contextually related non-target objects on ADL execution in patients with multi-domain mild cognitive impairment (MCI) and dementia. METHODS: We compared ADL execution in patients with MCI, dementia, and healthy elderly participants under two experimental conditions: One in which the target objects were embedded with contextually related non-target items that constituted the object set necessary to complete two additional (but unrequired) ADL tasks related to the target task, and a second, control condition where target objects were surrounded by isolated objects (they never constituted a whole set needed to complete an alternative ADL task)...
May 12, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28494135/prospective-association-between-body-mass-index-at-midlife-and-healthy-aging-among-french-adults
#19
Indunil Ruhunuhewa, Moufidath Adjibade, Valentina A Andreeva, Pilar Galan, Serge Hercberg, Karen E Assmann, Emmanuelle Kesse-Guyot
OBJECTIVE: To assess the association between midlife body mass index (BMI) and healthy aging (HA) in the French SU.VI.MAX cohort. METHODS: HA was assessed in 2007 to 2009 among 2,733 individuals, aged 45 to 60 years and free of diabetes, cardiovascular disease and cancer at baseline (1994-1995). HA was defined as not developing any major chronic disease, good physical and cognitive functioning, no limitations in instrumental activities of daily living, no depressive symptoms, no health-related limitations in social life, good overall self-perceived health, and no function-limiting pain...
May 11, 2017: Obesity
https://www.readbyqxmd.com/read/28491495/dorsolateral-prefrontal-cortex-contributes-to-the-impaired-behavioral-adaptation-in-alcohol-dependence
#20
Sinem Balta Beylergil, Anne Beck, Lorenz Deserno, Robert C Lorenz, Michael A Rapp, Florian Schlagenhauf, Andreas Heinz, Klaus Obermayer
Substance-dependent individuals often lack the ability to adjust decisions flexibly in response to the changes in reward contingencies. Prediction errors (PEs) are thought to mediate flexible decision-making by updating the reward values associated with available actions. In this study, we explored whether the neurobiological correlates of PEs are altered in alcohol dependence. Behavioral, and functional magnetic resonance imaging (fMRI) data were simultaneously acquired from 34 abstinent alcohol-dependent patients (ADP) and 26 healthy controls (HC) during a probabilistic reward-guided decision-making task with dynamically changing reinforcement contingencies...
2017: NeuroImage: Clinical
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