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https://www.readbyqxmd.com/read/28108852/missing-the-target-the-neural-processing-underlying-the-omission-error
#1
Rinaldo Livio Perri, Donatella Spinelli, Francesco Di Russo
The omissions are infrequent errors consisting in missing responses to the target stimuli. This is the first study aimed at investigating the brain activities associated with omissions in a decision-making task. We recorded event-related potentials (ERPs) in 12 subjects which reported a suitable number of omissions in a visual go/no-go task. We investigated both the pre- and post-stimulus brain activities associated with correct and omitted trials. The electrical neuroimaging technique (BESA) was adopted to extract the anterior insula (aIns) activity associated with the prefrontal P2 component (pP2) peaking about 300 ms after the stimulus and reflecting the stimulus-response mapping process...
January 20, 2017: Brain Topography
https://www.readbyqxmd.com/read/28108415/how-does-mindfulness-modulate-self-regulation-in-pre-adolescent-children-an-integrative-neurocognitive-review
#2
REVIEW
Rebekah Jane Kaunhoven, Dusana Dorjee
Pre-adolescence is a key developmental period in which complex intrinsic volitional methods of self-regulation are acquired as a result of rapid maturation within the brain networks underlying the self-regulatory processes of attention control and emotion regulation. Fostering adaptive self-regulation skills during this stage of development has strong implications for physical health, emotional and socio-economic outcomes during adulthood. There is a growing interest in mindfulness-based programmes for pre-adolescents with initial findings suggesting self-regulation improvements, however, neurodevelopmental studies on mindfulness with pre-adolescents are scarce...
January 17, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28102958/sliding-window-prior-data-assisted-compressed-sensing-for-mri-tracking-of-lung-tumors
#3
Eugene Yip, Jihyun Yun, Keith Wachowicz, Zsolt Gabos, Satyapal Rathee, B G Fallone
PURPOSE: Hybrid magnetic resonance imaging and radiation therapy devices are capable of imaging in real-time to track intrafractional lung tumor motion during radiotherapy. Highly accelerated magnetic resonance (MR) imaging methods can potentially reduce system delay time and/or improves imaging spatial resolution, and provide flexibility in imaging parameters. Prior Data Assisted Compressed Sensing (PDACS) has previously been proposed as an acceleration method that combines the advantages of 2D compressed sensing and the KEYHOLE view-sharing technique...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28100667/the-control-of-translational-accuracy-is-a-determinant-of-healthy-ageing-in-yeast
#4
Tobias von der Haar, Jane E Leadsham, Aimie Sauvadet, Daniel Tarrant, Ilectra S Adam, Kofo Saromi, Peter Laun, Mark Rinnerthaler, Hannelore Breitenbach-Koller, Michael Breitenbach, Mick F Tuite, Campbell W Gourlay
Life requires the maintenance of molecular function in the face of stochastic processes that tend to adversely affect macromolecular integrity. This is particularly relevant during ageing, as many cellular functions decline with age, including growth, mitochondrial function and energy metabolism. Protein synthesis must deliver functional proteins at all times, implying that the effects of protein synthesis errors like amino acid misincorporation and stop-codon read-through must be minimized during ageing. Here we show that loss of translational accuracy accelerates the loss of viability in stationary phase yeast...
January 2017: Open Biology
https://www.readbyqxmd.com/read/28100070/exploring-relationships-among-social-integration-social-isolation-self-rated-health-and-demographics-among-latino-day-laborers
#5
Kenneth C Steel, Maria Eugenia Fernandez-Esquer, John S Atkinson, Wendell C Taylor
OBJECTIVES: Research indicates social integration and social isolation are related to health, and Latino day laborers (LDLs) tend to be socially isolated and, thus, at high risk for adverse health consequences. relationships among social isolation, social integration, self-rated health (SRH), and demographics were examined in a sample of LDLs to contribute to the literature on social networks and health in this and other migrant populations. DESIGN: We analyzed data from 324 LDLs who participated in Proyecto SHILOS (Salud del Hombre Inmigrante Latino), a Houston-based survey of Latino immigrant men's health...
January 19, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28095004/correction-to-mandel-et-al-2015
#6
(no author information available yet)
Reports an error in "Self-critical perfectionism and depressive and anxious symptoms over 4 years: The mediating role of daily stress reactivity" by Tobey Mandel, David M. Dunkley and Molly Moroz (Journal of Counseling Psychology, 2015[Oct], Vol 62[4], 703-717). (The following abstract of the original article appeared in record 2015-32534-001.) This study of 150 community adults examined heightened emotional reactivity to daily stress as a mediator in the relationships between self-critical (SC) perfectionism and depressive and anxious symptoms over a period of 4 years...
January 16, 2017: Journal of Counseling Psychology
https://www.readbyqxmd.com/read/28072701/pathophysiology-of-refractory-obsessive-compulsive-disorder-a-study-of-visual-search-combined-with-overactive-performance-monitoring
#7
Qingxiao Liu, Bo Tan, Jing Zhou, Zhong Zheng, Ling Li, Yanchun Yang
Based on both functional and structural studies of excessive activity, fronto-striatal-thalamic-cortical and cortico-striatal circuits have been hypothesized to underlie the pathophysiology of obsessive-compulsive disorder (OCD). However, the neurobiological underpinnings of OCD refractory to medication and therapy remain controversial. This study aimed to evaluate neuroanatomical abnormalities of the whole brain and to evaluate visual processing in patients with refractory OCD.This study was comprised of 2 experiments...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28072586/assessing-the-quality-of-services-provided-in-the-teaching-hospitals-a-case-study-of-iran
#8
Ramin Ravangard, Payam Farhadi, Nasrin Shokrpour, Maryam Niyas, Zahra Sajjadnia
Service quality is the most important factor in the success of health care organizations; because of their vital and important services, even very small errors can be followed by great and irreparable harm and damage. This study aimed to assess the quality of services provided in the teaching hospitals affiliated to Shiraz University of Medical Sciences in 2015. This is an applied, cross-sectional, and descriptive-analytical study conducted in 2015 in the teaching hospitals affiliated to Shiraz University of Medical Sciences...
January 10, 2017: Health Care Manager
https://www.readbyqxmd.com/read/28072451/the-impact-of-salience-and-visual-working-memory-on-the-monitoring-and-control-of-saccadic-behavior-an-eye-tracking-and-eeg-study
#9
Matthew D Weaver, Clayton Hickey, Wieske van Zoest
In a concurrent eye-tracking and EEG study, we investigated the impact of salience on the monitoring and control of eye movement behavior and the role of visual working memory (VWM) capacity in mediating this effect. Participants made eye movements to a unique line-segment target embedded in a search display also containing a unique distractor. Target and distractor salience was manipulated by varying degree of orientation offset from a homogenous background. VWM capacity was measured using a change-detection task...
January 10, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28060005/exploration-of-health-status-illness-perceptions-coping-strategies-psychological-morbidity-and-quality-of-life-in-individuals-with-fecal-ostomies
#10
Simon R Knowles, Davina Tribbick, William R Connell, David Castle, Michael Salzberg, Michael A Kamm
PURPOSE: In a previous paper focusing on the common sense model (CSM) for ostomies in people with inflammatory bowel disease, cancer, and diverticular disease, we reported that (1) illness perceptions were directly related to illness status, and both illness perceptions and coping strategies (maladaptive coping) directly influenced anxiety and depression; (2) self-efficacy and emotion-focused coping style ameliorated depression but not anxiety; and (3) time since surgery was associated with improved health status, a reduction in negative illness perceptions, and increased emotional-focused coping...
January 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28059473/striosomal-dysfunction-affects-behavioral-adaptation-but-not-impulsivity-evidence-from-x-linked-dystonia-parkinsonism
#11
Christian Beste, Moritz Mückschel, Raymond Rosales, Aloysius Domingo, Lillian Lee, Arlene Ng, Christine Klein, Alexander Münchau
BACKGROUND: Executive functions including behavioral adaptation and impulse control are commonly impaired in movement disorders caused by striatal pathology. However, as yet it is unclear what aspects of behavioral abnormalities are related to pathology in which striatal subcomponent, that is, the matrix and the striosomes. We therefore studied cognitive control in X-linked dystonia-parkinsonism, a model disease of striosomal degeneration, using behavioral paradigms and EEG. METHODS: We studied genetically confirmed X-linked dystonia-parkinsonism patients (N = 21) in their early disease stages and healthy matched controls...
January 6, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28055858/icap-an-individualized-model-combining-gaze-parameters-and-image-based-features-to-predict-radiologists-decisions-while-reading-mammograms
#12
Ziba Gandomkar, Kevin Tay, William Ryder, Patrick C Brennan, Claudia Mello-Thoms
This study introduces an individualized tool for identifying mammogram interpretation errors, called eye-Computer Assisted Perception (iCAP). iCAP consists of two modules, one which processes areas marked by radiologists as suspicious for cancer and classifies these as False Positive (FP) or True Positive (TP) decisions, while the second module classifies fixated but not marked locations as False Negative (FN) or True-Negative (TN) decisions. iCAP relies on both radiologists' gaze-related parameters, extracted from eye tracking data, and image-based features...
December 28, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28050805/electrophysiological-correlates-reflect-the-integration-of-model-based-and-model-free-decision-information
#13
Ben Eppinger, Maik Walter, Shu-Chen Li
In this study, we investigated the interplay of habitual (model-free) and goal-directed (model-based) decision processes by using a two-stage Markov decision task in combination with event-related potentials (ERPs) and computational modeling. To manipulate the demands on model-based decision making, we applied two experimental conditions with different probabilities of transitioning from the first to the second stage of the task. As we expected, when the stage transitions were more predictable, participants showed greater model-based (planning) behavior...
January 3, 2017: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/28049408/detailed-simulation-of-cancer-exome-sequencing-data-reveals-differences-and-common-limitations-of-variant-callers
#14
Ariane L Hofmann, Jonas Behr, Jochen Singer, Jack Kuipers, Christian Beisel, Peter Schraml, Holger Moch, Niko Beerenwinkel
BACKGROUND: Next-generation sequencing of matched tumor and normal biopsy pairs has become a technology of paramount importance for precision cancer treatment. Sequencing costs have dropped tremendously, allowing the sequencing of the whole exome of tumors for just a fraction of the total treatment costs. However, clinicians and scientists cannot take full advantage of the generated data because the accuracy of analysis pipelines is limited. This particularly concerns the reliable identification of subclonal mutations in a cancer tissue sample with very low frequencies, which may be clinically relevant...
January 3, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28049306/transport-geometrical-and-topological-properties-of-stealthy-disordered-hyperuniform-two-phase-systems
#15
G Zhang, F H Stillinger, S Torquato
Disordered hyperuniform many-particle systems have attracted considerable recent attention, since they behave like crystals in the manner in which they suppress large-scale density fluctuations, and yet also resemble statistically isotropic liquids and glasses with no Bragg peaks. One important class of such systems is the classical ground states of "stealthy potentials." The degree of order of such ground states depends on a tuning parameter χ. Previous studies have shown that these ground-state point configurations can be counterintuitively disordered, infinitely degenerate, and endowed with novel physical properties (e...
December 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28049076/olfactory-identification-in-patients-with-schizophrenia%C3%A2-%C3%A2-the-influence-of-%C3%AE-endorphin-and-calcitonin-gene-related-peptide-concentrations
#16
M Urban-Kowalczyk, J Śmigielski, D Strzelecki
BACKGROUND: The relationship between the olfactory system and emotional processing is an area of growing interest in schizophrenia research. Both the orbitofrontal cortex and amygdala are involved in the processing of olfactory information, and olfactory deficits may be also influenced by endogenous opioids and calcitonin gene-related peptide (CGRP), which is probably involved in dopaminergic transmission. However, the relationship between endorphins and dopaminergic transmission has not been fully explored...
December 29, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28048810/su-f-i-25-reproducibility-of-phosphorus-mrs-and-work-measurements-for-evaluating-skeletal-muscle-metabolism
#17
F Settles, E Ripley, D Shengwen, G Clarke
PURPOSE: Skeletal muscle energetics were studied by phosphorus-31 MRS ((31) P-MRS) during exercise. The reproducibility of work performed and the MRS parameters were investigated. METHODS: Reproducibility of the (31) P-MRS exercise parameters was validated in five healthy volunteers (2 M/3 F, age 39.2 ± 21.9 yr, BMI 25.1 ± 4.8 kg/m(2) ). Five minute exercise of the vastus lateralis (VL) was performed on two separate occasions during MRS in a 3 Tesla MRI system...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046473/su-c-206-03-metal-artifact-reduction-in-x-ray-computed-tomography-based-on-local-anatomical-similarity
#18
X Dong, X Yang, J Rosenfield, E Elder, A Dhabaan
PURPOSE: Metal implants such as orthopedic hardware and dental fillings cause severe bright and dark streaking in reconstructed CT images. These artifacts decrease image contrast and degrade HU accuracy, leading to inaccuracies in target delineation and dose calculation. Additionally, such artifacts negatively impact patient set-up in image guided radiation therapy (IGRT). In this work, we propose a novel method for metal artifact reduction which utilizes the anatomical similarity between neighboring CT slices...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045303/-parsing-the-heterogeneity-of-psychopathy-and-aggression-differential-associations-across-dimensions-and-gender-correction-to-hecht-et-al-2016
#19
(no author information available yet)
Reports an error in "Parsing the heterogeneity of psychopathy and aggression: Differential associations across dimensions and gender" by Lisa K. Hecht, Joanna M. Berg, Scott O. Lilienfeld and Robert D. Latzman (Personality Disorders: Theory, Research, and Treatment, 2016[Jan], Vol 7[1], 2-14). In the article, there was an error in Table 3 and in the fifth paragraph of the Results. The correct information has been provided. (The following abstract of the original article appeared in record 2015-29370-001.) Psychopathy is a multidimensional construct that is broadly associated with both reactive (RA) and proactive (PA) aggression...
January 2017: Personality Disorders
https://www.readbyqxmd.com/read/28043892/genetic-influences-on-functional-connectivity-associated-with-feedback-processing-and-prediction-error-phase-coupling-of-theta-band-oscillations-in-twins
#20
Şükrü Barış Demiral, Simon Golosheykin, Andrey P Anokhin
Detection and evaluation of the mismatch between the intended and actually obtained result of an action (reward prediction error) is an integral component of adaptive self-regulation of behavior. Extensive human and animal research has shown that evaluation of action outcome is supported by a distributed network of brain regions in which the anterior cingulate cortex (ACC) plays a central role, and the integration of distant brain regions into a unified feedback-processing network is enabled by long-range phase synchronization of cortical oscillations in the theta band...
December 31, 2016: International Journal of Psychophysiology
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