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error-related negativity

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https://www.readbyqxmd.com/read/29243530/electrophysiological-markers-of-motivation-in-psychosis
#1
Kazuki Sueyoshi, Tomiki Sumiyoshi
Motivation is associated with electrophysiological markers, such as awake state delta oscillation and frontal alpha asymmetry, as well as event-related potentials, such as error-related negativity, feedback-related negativity, and prepulse inhibition. These indicators provide an objective measure of motivational deficits in psychiatric conditions, and response to treatment. Also, these modalities of brain activities are drawing attention as a target of neurofeedback training. The aim of this article is to provide a brief overview on electrophysiological findings relevant to the understanding of the mechanisms underlying impaired motivation in psychiatric disorders and clinical practice...
January 2018: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29241505/knowledge-behaviours-training-and-attitudes-of-nurses-during-preparation-and-administration-of-intravenous-medications-in-intensive-care-units-icu-a-multicenter-italian-study
#2
Marco Di Muzio, Corrado De Vito, Daniela Tartaglini, Paolo Villari
BACKGROUND: Medication errors can put at risk the life of patients hospitalized in the ICUs. These errors occur more frequently in the ICUs due to their peculiar medical framework. There is not much information about the knowledge, attitudes, behaviours and training needs of the nurses who work in ICUs towards the medication errors. OBJECTIVE: This study aims at describing the knowledge, attitudes, behaviours and training needs of the Italian nurses who work in ICUs towards the use of IV drugs, and identifying the strategies that nurses can adopt to prevent the occurrence of medication errors...
December 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/29241001/synthesis-of-conformationally-locked-cis-and-trans-bicyclo-4-4-0-mono-di-and-trioxadecane-modifications-of-galacto-and-glucopyranose-experimental-limiting-3jh-h-coupling-constants-for-the-estimation-of-carbohydrate-side-chain-populations-and-beyond
#3
Harsha Amarasekara, Suresh Dharuman, Takayuki Kato, David Crich
Hexopyranose side chains populate three staggered conformations, whose proportions can be determined from the three sets of ideal limiting 3JH5,H6R and 3JH5,H6S coupling constants in combination with the time-averaged experimental coupling constants. Literature values for the limiting coupling constants, obtained by the study of model compounds, the use of the Haasnoot-Altona and related equations, or quantum mechanical computations, can result in computed negative populations of one of the three ideal conformations...
December 14, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29238990/associations-between-developmental-changes-in-error-related-brain-activity-and-executive-functions-in-early-childhood
#4
Jennie K Grammer, William J Gehring, Frederick J Morrison
Behavioral evidence indicates that skills associated with children's cognitive control (e.g., response inhibition and attentional control) undergo rapid development during early childhood. A particularly important time is the transition to elementary school. Yet, at present, relatively little is known about developmental changes in the brain processes linked to cognitive control during this period, including those associated with error monitoring, including the error-related negativity (ERN) and the error positivity (Pe)...
December 14, 2017: Psychophysiology
https://www.readbyqxmd.com/read/29235136/reluctance-to-express-emotion-explains-relation-between-cognitive-distortions-and-social-competence-in-anxious-children
#5
Brandon G Scott, Armando A Pina, Julia H Parker
Guided by social information processing and affective social competence models, the focal objective of this research was to examine the relations among anxious children's cognitive distortions, social skill competence, and reluctance to express emotion. In addition, we explored whether children's attention control played any meaningful role. Using a sample of 111 anxious children (Mage  = 9.63, SD = 0.73; 75.7% girls; 56% Hispanic/Latino), we found that cognitive distortions were negatively related to social competence...
December 12, 2017: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/29234968/a-cross-national-analysis-of-the-association-between-years-of-implementation-of-opioid-substitution-treatments-and-drug-related-deaths-in-europe-from-1995-to-2013
#6
Phillip L Marotta, Charlotte A McCullagh
Data at the individual-level provide evidence that opioid substitution treatment (OST) programs protect against mortality for opioid dependent populations. Prior research has not examined the merits of national implementation of opioid substitution programs for reducing mortality at the country-level. This study elucidates longitudinal associations between country-level implementation of opioid substitution treatment programs on mortality rates of drug related deaths (DRD) from 1995 to 2013 in 30 European nations...
December 12, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29233279/pharmacy-student-engagement-in-the-evaluation-of-medication-documentation-within-an-ambulatory-care-electronic-medical-record
#7
Tatum Mead, Stephanie Schauner
BACKGROUND AND PURPOSE: An abundance of literature supports the benefits of electronic medical records (EMR) for improving overall healthcare quality. Identifying preventative care opportunities, reducing medical and medication related errors and incorporating clinical practice guidelines are just a few attributes of EMR implementation. The goals of this study were to engage experiential pharmacy students in the assessment of medication related documentation discrepancies in a newly implemented EMR system and to provide exposure to various aspects of conducting research...
May 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29231144/qsar-of-natural-sesquiterpene-lactones-as-inhibitors-of-myb-dependent-gene-expression
#8
Gloria Castellano, Lucia Redondo, Francisco Torrens
Protein c-Myb is a therapeutic target. Some sesquiterpene lactones suppress Myb-dependent gene expression, which results in a mechanism for their potential anti-cancer activity. Database ChEMBL is representative of lactones for physicochemical and physiochemical properties. Data presented for 31 natural lactones are discussed in terms of quantitative structure-activity relationships, which objective is to predict inhibitors of Myb-induced gene expression. Several constitutional descriptors are related to structure-activity...
December 11, 2017: Current Topics in Medicinal Chemistry
https://www.readbyqxmd.com/read/29231004/-establishment-of-automation-system-for-detection-of-alcohol-in-blood
#9
L L Tian, Lei Shen, J F Xue, M M Liu, L J Liang
OBJECTIVES: To establish an automation system for detection of alcohol content in blood. METHODS: The determination was performed by automated workstation of extraction-headspace gas chromatography (HS-GC). The blood collection with negative pressure, sealing time of headspace bottle and sample needle were checked and optimized in the abstraction of automation system. The automatic sampling was compared with the manual sampling. RESULTS: The quantitative data obtained by the automated workstation of extraction-HS-GC for alcohol was stable...
February 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29226961/detection-of-deception-event-related-potential-markers-of-attention-and-cognitive-control-during-intentional-false-responses
#10
Henning Gibbons, Robert Schnuerch, Christina Wittinghofer, Anne-Simone Armbrecht, Jutta Stahl
Successful deception requires the coordination of multiple mental processes, such as attention, conflict monitoring, and the regulation of emotion. We employed a simple classification task, assessing ERPs to further investigate the attentional and cognitive control components of (instructed) deception. In Experiment 1, 20 participants repeatedly categorized visually presented names of five animals and five plants. Prior to the experiment, however, each participant covertly selected one animal and one plant for deliberate misclassification...
December 11, 2017: Psychophysiology
https://www.readbyqxmd.com/read/29225065/an-unbiased-data-driven-age-related-structural-brain-parcellation-for-the-identification-of-intrinsic-brain-volume-changes-over-the-adult-lifespan
#11
Epifanio Bagarinao, Hirohisa Watanabe, Satoshi Maesawa, Daisuke Mori, Kazuhiro Hara, Kazuya Kawabata, Noritaka Yoneyama, Reiko Ohdake, Kazunori Imai, Michihito Masuda, Takamasa Yokoi, Aya Ogura, Toshihiko Wakabayashi, Masafumi Kuzuya, Norio Ozaki, Minoru Hoshiyama, Haruo Isoda, Shinji Naganawa, Gen Sobue
This study aims to elucidate age-related intrinsic brain volume changes over the adult lifespan using an unbiased data-driven structural brain parcellation. Anatomical brain images from a cohort of 293 healthy volunteers ranging in age from 21 - 86 years were analyzed using independent component analysis (ICA). ICA-based parcellation identified 192 component images, of which 174 (90.6%) showed a significant negative correlation with age and with some components being more vulnerable to aging effects than others...
December 7, 2017: NeuroImage
https://www.readbyqxmd.com/read/29220884/a-black-swan-in-clinical-laboratory-practice-the-analytical-error-due-to-interferences-in-immunoassay-methods
#12
Aldo Clerico, Lucia Belloni, Cinzia Carrozza, Mario Correale, Ruggero Dittadi, Claudio Dotti, Antonio Fortunato, Giulio Vignati, Gian Carlo Zucchelli, Marco Migliardi
It is well known that the results of immunoassay methods can be affected by specific or non-specific interferences, ranging from 0.4% to 4.0%. The presence of interference may greatly compromise the accuracy of immunoassay analyses causing an error in the measurement, producing false-positive or false-negative results. From a clinical point of view, these analytical errors may have serious implications for patient care because they can cause misdiagnosis or inappropriate treatment. Unfortunately, it is a very difficult task to identify the irregular analytical errors related to immunoassay methods because they are not detectable by normal laboratory quality control procedures, are reproducible within the test system, may be clinically plausible and are relatively rare...
December 7, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29219856/the-interaction-of-depressive-symptoms-and-hazardous-drinking-in-relation-to-tobacco-craving-among-treatment-seeking-depressed-smokers-sex-differences
#13
Rubén Rodríguez-Cano, Ana López-Durán, Daniel J Paulus, Carmela Martínez-Vispo, Elena Fernández Del Río, Elisardo Becoña, Michael J Zvolensky
OBJECTIVES: The present study sought to address whether there is sex effect in the interactive effect between depressive symptoms and hazardous drinking in the prediction of smoking craving after cognitive-behavioral smoking cessation treatment among those with at least mild depression. METHODS: Participants (n = 114, mean age 42.0, SD = 9.73, 64% women) were treatment-seeking smokers who attended 6 weekly 1-hour sessions involving psychological treatment for cessation...
December 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29216861/impaired-mixed-emotion-processing-in-the-right-ventrolateral-prefrontal-cortex-in-schizophrenia-an-fmri-study
#14
Ádám György Szabó, Kinga Farkas, Csilla Marosi, Lajos R Kozák, Gábor Rudas, János Réthelyi, Gábor Csukly
BACKGROUND: Schizophrenia has a negative effect on the activity of the temporal and prefrontal cortices in the processing of emotional facial expressions. However no previous research focused on the evaluation of mixed emotions in schizophrenia, albeit they are frequently expressed in everyday situations and negative emotions are frequently expressed by mixed facial expressions. METHODS: Altogether 37 subjects, 19 patients with schizophrenia and 18 healthy control subjects were enrolled in the study...
December 8, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29210194/error-related-brain-activity-and-anxiety-symptoms-in-youth-with-autism-spectrum-disorder
#15
Tamara E Rosen, Matthew D Lerner
Individuals with autism spectrum disorder (ASD) often experience symptoms associated with generalized anxiety disorder, obsessive-compulsive disorder, and social anxiety disorder. In other populations, these same symptoms are associated with a larger error-related negativity (ERN), an event-related potential that reflects endogenous threat sensitivity. As such, it is possible that the ERN may relate to the clinical presentation of anxiety in ASD. However, studies examining these associations in youth with ASD have yielded mixed results...
December 6, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29209188/age-related-decline-of-wrist-position-sense-and-its-relationship-to-specific-physical-training
#16
Ann Van de Winckel, Yu-Ting Tseng, Daniel Chantigian, Kaitlyn Lorant, Zinat Zarandi, Jeffrey Buchanan, Thomas A Zeffiro, Mia Larson, Becky Olson-Kellogg, Jürgen Konczak, Manda L Keller-Ross
Perception of limb and body positions is known as proprioception. Sensory feedback, especially from proprioceptive receptors, is essential for motor control. Aging is associated with a decline in position sense at proximal joints, but there is inconclusive evidence of distal joints being equally affected by aging. In addition, there is initial evidence that physical activity attenuates age-related decline in proprioception. Our objectives were, first, to establish wrist proprioceptive acuity in a large group of seniors and compare their perception to young adults, and second, to determine if specific types of training or regular physical activity are associated with preserved wrist proprioception...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29201347/the-creation-and-evaluation-of-a-model-to-simulate-the-probability-of-conception-in-seasonal-calving-pasture-based-dairy-heifers
#17
Caroline Fenlon, Luke O'Grady, Stephen Butler, Michael L Doherty, John Dunnion
Background: Herd fertility in pasture-based dairy farms is a key driver of farm economics. Models for predicting nulliparous reproductive outcomes are rare, but age, genetics, weight, and BCS have been identified as factors influencing heifer conception. The aim of this study was to create a simulation model of heifer conception to service with thorough evaluation. Methods: Artificial Insemination service records from two research herds and ten commercial herds were provided to build and evaluate the models...
2017: Irish Veterinary Journal
https://www.readbyqxmd.com/read/29196772/correlation-of-cue-locked-frn-and-feedback-locked-frn-in-the-auditory-monetary-incentive-delay-task
#18
Elena Krugliakova, Vasily Klucharev, Tommaso Fedele, Alexey Gorin, Aleksandra Kuznetsova, Anna Shestakova
Reflecting the discrepancy between received and predicted outcomes, the reward prediction error (RPE) plays an important role in learning in a dynamic environment. A number of studies suggested that the feedback-related negativity (FRN) component of an event-related potential, known to be associated with unexpected outcomes, encodes RPEs. While FRN was clearly shown to be sensitive to the probability of outcomes, the effect of outcome magnitude on FRN remains to be further clarified. In studies on the neural underpinnings of reward anticipation and outcome evaluation, a monetary incentive delay (MID) task proved to be particularly useful...
December 1, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29193737/laboratory-testing-in-patients-treated-with-direct-oral-anticoagulants-a-practical-guide-for-clinicians
#19
REVIEW
Jonathan Douxfils, Walter Ageno, Charles-Marc Samama, Sarah Lessire, Hugo Ten Cate, Peter Verhamme, Jean-Michel Dogné, François Mullier
One of the key benefits of the direct oral anticoagulants (DOACs) is that they do not require routine laboratory monitoring. Nevertheless, assessment of DOAC exposure and anticoagulant effects may become useful in various clinical scenarios. The four approved DOACs - apixaban, dabigatran etexilate, edoxaban and rivaroxaban - have different characteristics impacting assay selection and the interpretation of results. This article provides an updated overview on 1) which test to use (and their advantages and limitations), 2) when to assay DOAC levels, 3) how to interpret the results relating to bleeding risk, emergency situations and perioperative management, and 4) what is the impact of DOACs on routine and specialised coagulation assays...
November 29, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29192940/-the-relationship-of-interleukin-18-and-interleukin-6-levels-with-cognitive-functions-in-bipolar-disorder
#20
Filiz Civil Arslan, Ahmet Tiryaki, Evrim Özkorumak Karagüzel, Gizem Aral, Oğuz Sarıoğlu, İmran İnce, Sertaç Çankaya, Ahmet Alver
OBJECTIVE: Impairment in immune functions is proposed as a key factor in the cognitive decline in bipolar disorder (BD) however there is scarcity of research on the impact of inflammation on cognitive functions. Our aim is to compare IL-18 and IL-6 levels in BD patients and controls and to study the relationship between IL-18 and IL-6 levels and cognitive impairment METHOD: Thirty-six euthymic BD-I patients and 38 age, sex and educational level matched healthy controls were enrolled in the study...
2017: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
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