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Sacroiliitis

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https://www.readbyqxmd.com/read/28917996/poor-efficacy-of-tnf-inhibitors-in-non-radiographic-axial-spondyloarthritis-in-the-absence-of-objective-signs-a-bicentric-retrospective-study
#1
Céline Vidal, Cédric Lukas, Bernard Combe, Francis Berenbaum, Yves Marie Pers, Christian Jorgensen, Jérémie Sellam, Jacques Morel
OBJECTIVE: To compare BASDAI 50 response rate to TNFi in axial spondyloarthritis (axSpA) depending on the presence or not of objective signs of axSpA and to look for predictive factors of TNFi efficacy. METHODS: Patients diagnosed with axSpA according to ASAS criteria "clinical arm" and treated between January 2001 and September 2015 with TNFi were included. First group included patients with at least one objective sign such as arthritis, dactylitis, enthesitis, uveitis, inflammatory bowel disease, elevated C-reactive protein or radiological sacroiliitis, and second group included non-radiographic axSpA (nr-axSpA) patients without any objective sign corresponding to patients with inflammatory back pain and either a good response to NSAID or a SpA family history...
September 13, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28905097/color-doppler-and-spectral-doppler-ultrasound-detection-of-active-sacroiliitis-in-spondyloarthritis-compared-to-physical-examination-as-gold-standard
#2
Concepción Castillo-Gallego, Eugenio De Miguel, Miriam García-Arias, Chamaida Plasencia, Leticia Lojo-Oliveira, Emilio Martín-Mola
Sacroiliac joint (SIJ) involvement is a distinctive feature of spondyloarthritis (SpA). The main objective of this study was to assess the validity of color Doppler ultrasound (CDUS) in SIJ. This was a cross-sectional, blinded, case-control study of 108 cases divided into three groups: (a) 53 SpA patients with inflammatory back pain (IBP); (b) 28 SpA patients with no IBP; and (c) 27 healthy mechanical lumbar pain subjects. Physical examinations of the SIJs were assessed as positive or negative in each SIJ and were used as the gold standard...
September 13, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28894334/spondyloarthropathy-diagnostic-imaging-criteria-for-the-detection-of-sacroiliitis
#3
Moacir Ribeiro de Castro, Sonia de Aguiar Vilela Mitraud, Marina Celli Francisco, Artur da Rocha Corrêa Fernandes, Eloy de Ávila Fernandes
Diagnostic imaging is crucial to the diagnosis and monitoring of spondyloarthropathies. Magnetic resonance imaging is the most relevant tool for the early detection of sacroiliitis, allowing the institution of therapeutic strategies to impede the progression of the disease. This study illustrates the major criteria for a magnetic resonance imaging-based diagnosis of spondyloarthropathy. The cases selected here present images obtained from the medical records of patients diagnosed with sacroiliitis over a two-year period at our facility, depicting the active and chronic, irreversible forms of the disease...
July 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28882616/screening-of-inflammatory-bowel-disease-and-spondyloarthritis-for-referring-patients-between-rheumatology-and-gastroenterology
#4
Jesús Sanz Sanz, Xavier Juanola Roura, Daniel Seoane-Mato, Miguel Montoro, Fernando Gomollón
OBJECTIVE: To define clinical screening criteria for spondyloarthritis (SpA) in patients with inflammatory bowel disease (IBD) and vice versa, which can be used as a reference for referring them to the rheumatology or gastroenterology service. METHOD: Systematic literature review and a two-round Delphi method. The scientific committee and the expert panel were comprised of 2 rheumatologists and 2 gastroenterologists, and 7 rheumatologists and 7 gastroenterologists, respectively...
September 4, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28810926/the-association-between-sonographic-enthesitis-and-radiographic-damage-in-psoriatic-arthritis
#5
Ari Polachek, Richard Cook, Vinod Chandran, Dafna D Gladman, Lihi Eder
BACKGROUND: To examine the association between sonographic enthesitis and the severity of radiographic features of damage in the peripheral and axial joints in psoriatic arthritis (PsA). METHODS: A cross-sectional analysis was conducted in patients with PsA. The MAdrid Sonography Enthesitis Index (MASEI) scoring system was used to quantify the extent of sonographic entheseal abnormalities. Radiographic damage in the peripheral joints and spine was assessed by the modified Steinbrocker score (mSS), Modified New York Criteria for sacroiliitis, and the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS)...
August 15, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28798229/role-of-technetium-99m-methylene-diphosphonate-spect-ct-in-the-detection-of-sacroiliitis-in-patients-with-spondyloarthropathy-comparison-with-clinical-markers-and-mri
#6
Rahul V Parghane, Baljinder Singh, Aman Sharma, Harmandeep Singh, Paramjit Singh, Anish Bhattacharya
Rationale: To evaluate the role of (99m)Tc-MDP SPECT/CT for the detection of sacroiliitis in spondyloarthopathies (SpA) and comparison with clinical markers and MRI. Methods: A total of 155 diagnosed patients (83M : 72 F; mean age 35.80±12.40 years; range 18-60 years ) with SpA as per the European Spondyloarthropathy Study Group criteria (ESSG) criteria were prospectively included All the patients were subjected to clinical evaluation (using BASDAI scoring), ESR, CRP levels, planar (99m)Tc MDP bone scintigraphy, hybrid SPECT/CT and MRI of the pelvic region...
August 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28776360/biomarkers-imaging-and-disease-activity-indices-in-patients-with-early-axial-spondyloarthritis-the-italian-arm-of-the-spondyloarthritis-caught-early-space-study
#7
M Lorenzin, A Ortolan, S Vio, M Favero, F Oliviero, M Zaninotto, C Cosma, C Lacognata, L Punzi, R Ramonda
The study aimed to evaluate biomarkers facilitating early diagnosis of axial spondyloarthritis (axSpA) and correlations between them and disease activity parameters and imaging indexes. Patients with low back pain (LBP) (≥3 months, ≤2 years, onset ≤45 years) participating in the Italian arm of the SpondyloArthritis-Caught-Early SPACE study underwent a physical examination, questionnaires, laboratory tests, X-rays and MRI of the spine and sacroiliac joints (SIJ). An expert rheumatologist formulated axSpA diagnosis in accordance with Assessment of SpondyloArthritis International Society (ASAS) criteria...
August 3, 2017: Reumatismo
https://www.readbyqxmd.com/read/28774456/conventional-radiology-in-spondyloarthritis
#8
REVIEW
Alberto Bazzocchi, Maria Pilar Aparisi Gómez, Giuseppe Guglielmi
Spondyloarthritides are of a group of inflammatory rheumatic diseases, with negative rheumatoid factor, associated with the HLA-B27 gene. They comprise ankylosing spondylitis, psoriatic arthritis, reactive arthritis, and enteropathic-related spondylitis. The presence of sacroiliitis represents the most characteristic feature of these disorders and is an important criterion in diagnosis. Nonradiographic axial spondyloarthritis is a new classification concept. Conventional radiography is recommended as the first imaging method to diagnose sacroiliitis and different entities and to monitor established structural changes...
September 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28757344/clinical-predictors-of-magnetic-resonance-imaging-detected-sacroiliitis-in-children-with-enthesitis-related-arthritis
#9
Myriame Bou Antoun, Catherine Adamsbaum, Luca Semerano, Isabelle Koné-Paut, Linda Rossi-Semerano
OBJECTIVES: To determine the predictors of sacroiliitis detected by magnetic resonance imaging (MRI) in children with enthesitis-related arthritis. METHODS: In this retrospective, longitudinal study, we retrieved clinical and laboratory data from the charts of patients with confirmed enthesitis related arthritis and evaluated their association with magnetic sacroiliitis detected at first MRI after disease onset. The MRI images of sacroiliac joints were read by 2 independent radiologists and validated against those from 25 age- and sex-matched subjects with known non-rheumatologic conditions...
July 27, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28749173/mri-assessment-of-sacroiliitis-for-the-diagnosis-of-axial-spondyloarthropathy-comparison-of-fat-saturated-t2-stir-and-contrast-enhanced-sequences
#10
Siyoun Sung, Hyun Su Kim, Jong Won Kwon
OBJECTIVE: To evaluate whether there are significant differences between contrast-enhanced fat-saturated T1 weighted imaging and non-enhanced fat-suppression imaging for diagnosing sacroiliitis in patients with inflammatory back pain. METHODS: 92 patients, consisting of 46 males and 46 females (mean age: 34 years; range: 15-63 years), who met at least 4 out of 5 Assessment in SpondyloArthritis international Society criteria for inflammatory low back pain were enrolled in this study...
September 4, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28741366/comparison-of-bi-exponential-and-mono-exponential-models-of-diffusion-weighted-imaging-for-detecting-active-sacroiliitis-in-ankylosing-spondylitis
#11
Haitao Sun, Kai Liu, Hao Liu, Zongfei Ji, Yan Yan, Lindi Jiang, Jianjun Zhou
Background There has been a growing need for a sensitive and effective imaging method for the differentiation of the activity of ankylosing spondylitis (AS). Purpose To compare the performances of intravoxel incoherent motion (IVIM)-derived parameters and the apparent diffusion coefficient (ADC) for distinguishing AS-activity. Material and Methods One hundred patients with AS were divided into active (n = 51) and non-active groups (n = 49) and 21 healthy volunteers were included as control. The ADC, diffusion coefficient ( D), pseudodiffusion coefficient ( D*), and perfusion fraction ( f) were calculated for all groups...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28739431/protocol-optimization-of-sacroiliac-joint-mr-imaging-at-3-tesla-impact-of-coil-design-and-motion-resistant-sequences-on-image-quality
#12
P A Gondim Teixeira, M Bravetti, G Hossu, S Lecocq, D Petit, D Loeuille, A Blum
PURPOSE: To evaluate the impact of coil design and motion-resistant sequences on the quality of sacroiliac magnetic resonance imaging (MRI) examination in patients with spondyloarthropathy. PATIENTS AND METHODS: One hundred and twenty-one patients with suspected sacroiliitis and referred for MRI of the sacroiliac joints were retrospectively evaluated with MRI at 3-Tesla. There were 78 women and 43 men with a mean age of 36.7±11.5 (SD) years (range: 15.8-78.4 years)...
July 21, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28732137/prevalence-of-sacroiliitis-in-inflammatory-bowel-disease-using-a-standardized-ct-scoring-system
#13
Jonathan Chan, Ismail Sari, David Salonen, Mark S Silverberg, Nigil Haroon, Robert D Inman
OBJECTIVES: There is an increasing emphasis on early identification and treatment of ankylosing spondylitis (AS) of which the hallmark is sacroiliitis. Patients with inflammatory bowel disease (IBD) are at increased risk of AS and often receive CT scans of their abdomen affording clinicians the opportunity to determine the presence of sacroiliitis. Previous studies using CT have relied only on radiologist's gestalt or a non-validated adaptation of the mNY criteria. Our aim is to assess the prevalence of sacroiliitis in IBD using a validated screening tool and to determine how frequently these patients are referred for rheumatologic evaluation...
July 21, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28693033/axial-involvement-according-to-asas-criteria-in-an-observational-psoriatic-arthritis-cohort
#14
Pedro David Carvalho, Florencia Savy, Carmen Moragues, Xavier Juanola, Jesus Rodriguez-Moreno
The definition of axial involvement in psoriatic arthritis (PsA) is still under debate. Currently, the axial spondyloarthritis (SpA) criteria defined by Assessment of Spondyloarthritis International Society (ASAS) may be the most adequate.(1) The aims of present study were to assess axial involvement according to ASAS criteria in an observational PsA cohort and define the clinical characteristics more associated with this kind of involvement. Our study included consecutive patients who had a visit in a tertiary Rheumatology centre...
April 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28690741/-osteopecilia-associated-with-psoriatic-arthritis
#15
Zeineb Alaya, Walid Osman, Laassad Hassini, Houneida Zaghouani, Nader Naouar, Elyès Bouajina
Osteopecilia is a benign and rare condensing osteopathy. Its association with inflammatory rheumatism is very rare. We here report the case of a 25-year old patient with skin psoriasis, presenting with groin pain of inflammatory origin. Physical examination showed limitation of hip motions, lower limb-length inequality and pain on right sacroiliac mobilization. Laboratory tests showed inflammatory syndrome and negative immunological assessment. The radiograph of the pelvis revealed osteopecilia associated with destructive coxitis...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28684556/sacroiliac-radiographic-progression-in-recent-onset-axial-spondyloarthritis-the-5-year-data-of-the-desir-cohort
#16
Maxime Dougados, Alexandre Sepriano, Anna Molto, Miranda van Lunteren, Sofia Ramiro, Manouk de Hooge, Rosaline van den Berg, Victoria Navarro Compan, Christophe Demattei, Robert Landewé, Désirée van der Heijde
OBJECTIVE: To estimate sacroiliac joint radiographic (X-SIJ) progression in patients with axial spondyloarthritis (axSpA) and to evaluate the effects of inflammation on MRI (MRI-SIJ) on X-SIJ progression. METHODS: X-SIJ and MRI-SIJ at baseline and after 2 and 5 years in patients with recent onset axSpA from the DESIR cohort were scored by three central readers. Progression was defined as (1) the shift from non-radiographic (nr) to radiographic (r) sacroiliitis (by modified New York (mNY) criteria) or alternative criteria, (2) a change of at least one grade or (3) a change of at least one grade but ignoring a change from grade 0 to 1...
July 6, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28681364/treatment-of-a-case-of-ulcerative-colitis-with-sacroiliitis-using-granulocyte-and-monocyte-adsorption-apheresis
#17
Hitoshi Ichikawa, Jin Imai, Hajime Mizukami, Takayuki Shirai, Norihito Watanabe
In Japan, sacroiliitis is a very rare extraintestinal manifestation in patients with ulcerative colitis (UC), and it typically presents with intestinal symptoms. Radiography is used for diagnosis, and reveals erosions, sclerosis, and ankylosis, but magnetic resonance imaging is more useful for early detection. The treatment of spondyloarthropathy such as sacroiliitis and spondylitis includes physiotherapy, nonsteroidal anti-inflammatory drugs, sulfasalazine, and immunomodulators. In patients intolerant or cases refractory to these treatments, anti-tumor necrosis factor agents are recommended...
July 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/28663306/the-yield-of-a-positive-mri-of-the-spine-as-imaging-criterion-in-the-asas-classification-criteria-for-axial-spondyloarthritis-results-from-the-space-and-desir-cohorts
#18
Zineb Ez-Zaitouni, Pauline Ac Bakker, Miranda van Lunteren, Manouk de Hooge, Rosaline van den Berg, Monique Reijnierse, Karen Minde Fagerli, Robert Bm Landewé, Roberta Ramonda, Lennart Th Jacobsson, Alain Saraux, Gregory Lenczner, Antoine Feydy, Jean Baptiste Pialat, Fabrice Thévenin, Floris A van Gaalen, Désirée van der Heijde
OBJECTIVES: To assess the prevalence of spinal inflammation on MRI in patients with chronic back pain (CBP) of maximally 3 years duration and to evaluate the yield of adding a positive MRI-spine as imaging criterion to the Assessment of SpondyloArthritis international Society (ASAS) classification criteria for axial spondyloarthritis (axSpA). METHODS: Baseline imaging of the sacroiliac joints (X-SI), MRI of the sacroiliac joints (MRI-SI) and MRI-spine were scored by ≥2 experienced central readers per modality in the SPondyloArthritis Caught Early (SPACE) and DEvenir des Spondylarthropathies Indifférenciées Récentes (DESIR) cohorts...
October 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28662723/hla-b27-antigen-in-middle-eastern-and-arab-countries-systematic-review-of-the-strength-of-association-with-axial-spondyloarthritis-and-methodological-gaps
#19
Nelly Raymond Ziade
BACKGROUND: Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population. Current Assessment of Spondyloarthritis International Society (ASAS) classification criteria of AxSpA rely either on sacroiliitis on imaging plus one SpA feature or positive HLAB27 antigen plus two SpA features, in a patient with chronic low back pain and age at onset of less than 45 years. Therefore, HLA-B27 is a central feature in SpA classification and plays a pivotal role in referral strategies and early diagnosis...
June 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28660225/incidental-unilateral-tuberculous-sacroiliitis-detected-by-18-f-fdg-pet-ct-in-a-patient-with-abdominal-tuberculosis
#20
Domenico Albano, Giorgio Treglia, Paolo Desenzani, Francesco Bertagna
Tuberculosis is a systemic disease which involves skeletal and articular system very rarely. Osteoarticular tuberculosis commonly occurs in the vertebral column and more rarely in the sacroiliac joints. In this study, we report a 44-years-old male patient with low-grade fever, malabsorption syndrome, abdominal and pelvic ascites and low-back pain, that underwent (18)F-FDG PET/CT for identifying the cause of signs and symptoms after a negative abdominal CT and negative thorax radiography. The study revealed increased tracer uptake at the peritoneal ascites and at the right sacroiliac joint in absence of bone alteration suggesting a sacroiliitis...
2017: Asia Oceania Journal of Nuclear Medicine & Biology
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