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https://www.readbyqxmd.com/read/29450135/development-of-a-specific-index-to-detect-malnutrition-in-athletes-validity-in-weight-class-or-intermittent-fasted-athletes
#1
François D Desgorces, Christophe Moinard, Mounir Chennaoui, Jean-François Toussaint, Cyril Petibois, Philippe Noirez
Fasted or weight-category athletes manage their training under strict diet conditions that could impair the stress-recovery balance and result in acute or chronic fatigue. However, to date, no validated biomarker are available to quantify this phenomena. The aim of this study was to assess the validity of a specific index combining plasma albumin and weight change to detect nutrition-related risks of fatigue increase and under-performance in athletes experiencing particular nutritional conditions. An athlete's nutrition risk index (ANRI) equation, based on data from lightweight and heavyweight rowers, was developed using relationship between plasma albumin concentrations combined to weight changes with sport performance and overtraining scores and was tested by odds ratio for failure...
June 2017: Biochimie open
https://www.readbyqxmd.com/read/29447348/transcriptome-analysis-reveals-intermittent-fasting-induced-genetic-changes-in-ischemic-stroke
#2
Joonki Kim, Sung-Wook Kang, Karthik Mallilankaraman, Sang-Ha Baik, James C Lim, Priyanka Balaganapathy, David T She, Ker-Zhing Lok, David Y Fann, Uma Thambiayah, Sung-Chun Tang, Alexis M Stranahan, S Thameem Dheen, Mathias Gelderblom, Raymond C Seet, Vardan T Karamyan, Raghu Vemuganti, Christopher G Sobey, Mark P Mattson, Dong-Gyu Jo, Thiruma V Arumugam
Genetic changes due to dietary intervention in the form of either calorie restriction (CR) or intermittent fasting (IF) are not reported in detail until now. However, it is well established that both CR and IF extend the lifespan and protect against neurodegenerative diseases and stroke. The current research aims were first to describe the transcriptomic changes in brains of IF mice and, second, to determine whether IF induces extensive transcriptomic changes following ischemic stroke to protect the brain from injury...
February 13, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29438660/reliability-of-hunger-related-assessments-during-24-hour-fasts-and-their-relationship-to-body-composition-and-subsequent-energy-compensation
#3
Grant M Tinsley, M Lane Moore, Austin J Graybeal
Many diets employ regular periods of fasting that extend beyond a typical overnight fast (i.e. intermittent fasting [IF]). Evaluation of acute fasting responses provides information concerning the potential theoretical rationale for IF. The purpose of the present investigation was to assess the test-retest reliability of hunger-related variables during 24-hour fasts and the relationship between these variables and body composition, as well as subsequent energy intake (EI) after fasting. Eleven participants (6 F, 5 M) completed two 24-hour fasts after being provided a 3-day standardized weight-maintenance diet...
February 10, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29430025/reconnection-driven-magnetohydrodynamic-turbulence-in-a-simulated-coronal-hole-jet
#4
Vadim M Uritsky, Merrill A Roberts, C Richard DeVore, Judith T Karpen
Extreme-ultraviolet and X-ray jets occur frequently in magnetically open coronal holes on the Sun, especially at high solar latitudes. Some of these jets are observed by white-light coronagraphs as they propagate through the outer corona toward the inner heliosphere, and it has been proposed that they give rise to microstreams and torsional Alfvén waves detected in situ in the solar wind. To predict and understand the signatures of coronal-hole jets, we have performed a detailed statistical analysis of such a jet simulated with an adaptively refined magnetohydrodynamics model...
March 10, 2017: Astrophysical Journal
https://www.readbyqxmd.com/read/29429622/step-length-determines-minimum-toe-clearance-in-older-adults-and-people-with-parkinson-s-disease
#5
Lisa Alcock, Brook Galna, Ruth Perkins, Sue Lord, Lynn Rochester
Reduced foot clearance when walking may increase the risk of trips and falls in people with Parkinson's disease (PD). Changes in foot clearance in people with PD are likely to be associated with temporal-spatial characteristics of gait such as walking slowly which evokes alterations in the temporal-spatial control of stepping patterns. Enhancing our understanding of the temporal-spatial determinants of foot clearance may inform the design of falls prevention therapies. Thirty-six people with PD and 38 age-matched controls completed four intermittent walks under two conditions: self-selected and fast gait velocity...
December 13, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29419624/intermittent-fasting-interventions-for-treatment-of-overweight-and-obesity-in-adults-a-systematic-review-and-meta-analysis
#6
Leanne Harris, Sharon Hamilton, Liane B Azevedo, Joan Olajide, Caroline De Brún, Gillian Waller, Vicki Whittaker, Tracey Sharp, Mike Lean, Catherine Hankey, Louisa Ells
OBJECTIVE: To examine the effectiveness of intermittent energy restriction in the treatment for overweight and obesity in adults, when compared to usual care treatment or no treatment. INTRODUCTION: Intermittent energy restriction encompasses dietary approaches including intermittent fasting, alternate day fasting, and fasting for two days per week. Despite the recent popularity of intermittent energy restriction and associated weight loss claims, the supporting evidence base is limited...
February 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29405359/intermittent-fasting-in-type-2-diabetes-mellitus-and-the-risk-of-hypoglycaemia-a-randomized-controlled-trial
#7
B T Corley, R W Carroll, R M Hall, M Weatherall, A Parry-Strong, J D Krebs
AIMS: To establish whether the risk of hypoglycaemia is greater with 2 consecutive days of very-low-calorie diet compared with 2 non-consecutive days of very-low-calorie diet in people with Type 2 diabetes. METHODS: This was a non-blinded randomized parallel group interventional trial of intermittent fasting in adults. The participants had a BMI of 30-45 kg/m2 , Type 2 diabetes treated with metformin and/or hypoglycaemic medications and an HbA1c concentration of 50-86 mmol/mol (6...
February 6, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29403155/fluctuation-of-blood-glucose-levels-in-an-infant-with-an-ileostomy-on-continuous-glucose-monitoring-a-case-report
#8
Seiichi Tomotaki, Tetsuo Naramura, Junko Hanakawa, Katsuaki Toyoshima, Koji Muroya, Masanori Adachi
Infants with an ileostomy can be at high risk of hypoglycemia because of inadequate nutritional intake; however, there are no reports investigating blood glucose (BG) in infants with ileostomy. We experienced a case of an extremely low birth weight infant who was born at 24 wk of gestation and weighted 623 g. He received an ileostomy because of an intestinal perforation. After the ileostomy, he had recurrent hypoglycemia. Continuous glucose monitoring showed fluctuation of BG levels (postprandial BG elevations and subsequent declines) and non-fasting hypoglycemia, which were undetectable with intermittent fasting BG measurement...
2018: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/29396375/corrigendum-to-metabolic-adaptation-to-intermittent-fasting-is-independent-of-peroxisome-proliferator-activated-receptor-alpha-mol-metab-7-2018-80-89
#9
Guolin Li, Chad N Brocker, Tingting Yan, Cen Xie, Kristopher W Krausz, Rong Xiang, Frank J Gonzalez
No abstract text is available yet for this article.
January 23, 2018: Molecular Metabolism
https://www.readbyqxmd.com/read/29394908/intermittent-fasting-energy-balance-and-associated-health-outcomes-in-adults-study-protocol-for-a-randomised-controlled-trial
#10
Iain Templeman, Dylan Thompson, Javier Gonzalez, Jean-Philippe Walhin, Sue Reeves, Peter J Rogers, Jeffrey M Brunstrom, Leonidas G Karagounis, Kostas Tsintzas, James A Betts
BACKGROUND: Prior studies have shown that intermittent fasting is capable of producing improvements in body weight and fasted health markers. However, the extent to which intermittent fasting incurs compensatory changes in the components of energy balance and its impact on postprandial metabolism are yet to be ascertained. METHODS: A total of 30-36 lean participants and 30-36 overweight/obese participants will be recruited to provide two separate study groups who will undergo the same protocol...
February 2, 2018: Trials
https://www.readbyqxmd.com/read/29387326/performance-of-electrophysiologic-study-in-an-asymptomatic-patient-with-type-2-intermittent-brugada-syndrome-to-do-or-not-to-do
#11
Kaveh Hosseini, Mansour Jahangiri, Ali Vasheghani Farahani
Background: Brugada syndrome (BrS) is an inherited channelopathy, which is associated with sudden cardiac death due to rapid polymorphic VT or VF. There is no definite consensus regarding the management of asymptomatic patients. Some experts advocate close follow-up; others propose the programmed stimulation for risk stratification. We aimed to evaluate the benefit of complete atrial and ventricular stimulation in patients with BrS and palpitation. Case Presentation: A 30-year-old man was admitted to our hospital because of a family history of sudden cardiac death (SCD) at age less than 45 years...
2018: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/29387256/the-effects-of-diurnal-intermittent-fasting-on-the-wake-promoting-neurotransmitter-orexin-a
#12
Aljohara S Almeneessier, Mohammed Alzoghaibi, Abdulrahman A BaHammam, Mahmoud G Ibrahim, Awad H Olaish, Samar Z Nashwan, Ahmed S BaHammam
BACKGROUND: Food restriction has been demonstrated to increase the alertness in different species and to increase the levels of the wake-promoting neurotransmitter orexin. We hypothesized that diurnal intermittent fasting (DIF) increases orexin-A levels during fasting. Therefore, we conducted this study to assess the effects of DIF, during the month of Ramadan, on orexin, while controlling for lifestyle changes that may accompany Ramadan such as sleep duration, bedtime and wake time, energy expenditure, light exposure, and food...
January 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29387000/intermittent-fasting-applied-in-combination-with-rotenone-treatment-exacerbates-dopamine-neurons-degeneration-in-mice
#13
Giuseppe Tatulli, Nico Mitro, Stefano M Cannata, Matteo Audano, Donatella Caruso, Giovanna D'Arcangelo, Daniele Lettieri-Barbato, Katia Aquilano
Intermittent fasting (IF) was suggested to be a powerful nutritional strategy to prevent the onset of age-related neurodegenerative diseases associated with compromised brain bioenergetics. Whether the application of IF in combination with a mitochondrial insult could buffer the neurodegenerative process has never been explored yet. Herein, we defined the effects of IF in C57BL/6J mice treated once per 24 h with rotenone (Rot) for 28 days. Rot is a neurotoxin that inhibits the mitochondrial complex I and causes dopamine neurons degeneration, thus reproducing the neurodegenerative process observed in Parkinson's disease (PD)...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29386999/intermittent-fasting-alleviates-the-increase-of-lipoprotein-lipase-expression-in-brain-of-a-mouse-model-of-alzheimer-s-disease-possibly-mediated-by-%C3%AE-hydroxybutyrate
#14
Jingzhu Zhang, Xinhui Li, Yahao Ren, Yue Zhao, Aiping Xing, Congmin Jiang, Yanqiu Chen, Li An
Intermittent fasting has been demonstrated to protect against Alzheimer's disease (AD), however, the mechanism is unclear. Histone acetylation and lipoprotein lipase (LPL) are involved in AD progression. Importantly, LPL has been documented to be regulated by histone deacetylases (HDACs) inhibitors (increase histone acetylation level) in adipocyte and mesenchymal stem cells, or by fasting in adipose and muscle tissues. In brain, however, whether histone acetylation or fasting regulates LPL expression is unknown...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29382505/independent-relationships-between-cardinal-features-of-obstructive-sleep-apnea-and-glycometabolism-a-cross-sectional-study
#15
Juanjuan Zou, Yunyan Xia, Huajun Xu, Yiqun Fu, Yingjun Qian, Xinyi Li, Xiaolong Zhao, Jianyin Zou, Lili Meng, Suru Liu, Huaming Zhu, Hongliang Yi, Jian Guan, Bin Chen, Shankai Yin
BACKGROUND: Obstructive sleep apnea (OSA) is associated with abnormal glycometabolism; however, the cardinal features of OSA, such as sleep fragmentation (SF) and intermittent hypoxia (IH), have yet to show clear, independent associations with glycometabolism. METHODS: We enrolled 1834 participants with suspected OSA from July 2008 to July 2013 to participate in this study. Polysomnographic variables, biochemical indicators, and physical measurements were collected for each participant...
January 27, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29368646/phenos-a-high-throughput-and-flexible-tool-for-microorganism-growth-phenotyping-on-solid-media
#16
David B H Barton, Danae Georghiou, Neelam Dave, Majed Alghamdi, Thomas A Walsh, Edward J Louis, Steven S Foster
BACKGROUND: Microbial arrays, with a large number of different strains on a single plate printed with robotic precision, underpin an increasing number of genetic and genomic approaches. These include Synthetic Genetic Array analysis, high-throughput Quantitative Trait Loci (QTL) analysis and 2-hybrid techniques. Measuring the growth of individual colonies within these arrays is an essential part of many of these techniques but is useful for any work with arrays. Measurement is typically done using intermittent imagery fed into complex image analysis software, which is not especially accurate and is challenging to use effectively...
January 24, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/29357088/intermittent-nocturnal-hypoxia-and-metabolic-risk-in-obese-adolescents-with-obstructive-sleep-apnea
#17
Indra Narang, Brian W McCrindle, Cedric Manlhiot, Zihang Lu, Suhail Al-Saleh, Catherine S Birken, Jill Hamilton
PURPOSE: There is conflicting data regarding the independent associations of obstructive sleep apnea (OSA) with metabolic risk in obese youth. Previous studies have not consistently addressed central adiposity, specifically elevated waist to height ratio (WHtR), which is associated with metabolic risk independent of body mass index. OBJECTIVE: The objective of this study was to determine the independent effects of the obstructive apnea-hypopnea index (OAHI) and associated indices of nocturnal hypoxia on metabolic function in obese youth after adjusting for WHtR...
January 22, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29353457/fasting-and-fast-food-diet-play-an-opposite-role-in-mice-brain-aging
#18
Paola Castrogiovanni, Giovanni Li Volti, Cristina Sanfilippo, Daniele Tibullo, Fabio Galvano, Michele Vecchio, Roberto Avola, Ignazio Barbagallo, Lucia Malaguarnera, Sergio Castorina, Giuseppe Musumeci, Rosa Imbesi, Michelino Di Rosa
Fasting may be exploited as a possible strategy for prevention and treatment of several diseases such as diabetes, obesity, and aging. On the other hand, high-fat diet (HFD) represents a risk factor for several diseases and increased mortality. The aim of the present study was to evaluate the impact of fasting on mouse brain aging transcriptome and how HFD regulates such pathways. We used the NCBI Gene Expression Omnibus (GEO) database, in order to identify suitable microarray datasets comparing mouse brain transcriptome under fasting or HFD vs aged mouse brain transcriptome...
January 20, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29345287/intermittent-calorie-restriction-enhances-epithelial-mesenchymal-transition-through-the-alteration-of-energy-metabolism-in-a-mouse-tumor-model
#19
Osamu Kusuoka, Rina Fujiwara-Tani, Chie Nakashima, Kiyomu Fujii, Hitoshi Ohmori, Takuya Mori, Shingo Kishi, Yoshihiro Miyagawa, Kei Goto, Isao Kawahara, Hiroki Kuniyasu
The effect of intermittent calorie restriction (ICR) on cancer is controversial. In this study, we examined the effects of ICR and food content in syngeneic BALB/c mice injected with CT26 mouse colon cancer cells. Mice were subjected to 24-h fasting once a week for 4 weeks, and then provided with a control, high-calorie, or trans fatty acid-rich diet. While ICR resulted in increases in tumor weights, metastasis and in the number of cancer stem cells (CSCs) in the tumors or blood of mice fed the control and high-fat diets, it had no effect on body weight after 4 weeks...
February 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29327228/postoperative-intermittent-fasting-prevents-hippocampal-oxidative-stress-and-memory-deficits-in-a-rat-model-of-chronic-cerebral-hypoperfusion
#20
Yuan Hu, Miao Zhang, Yunyun Chen, Ying Yang, Jun-Jian Zhang
PURPOSE: Whether intermittent fasting (IF) treatment after stroke can prevent its long-term detrimental effects remains unknown. Here, we investigate the effects of postoperative IF on cognitive deficits and its underlying mechanisms in a permanent two-vessel occlusion (2VO) vascular dementia rat model. METHODS: Rats were subjected to either IF or ad libitum feeding 1 week after 2VO surgery. The cognition of rats was assessed using the novel object recognition (NOR) task and Morris water maze (MWM) 8 weeks after surgery...
January 11, 2018: European Journal of Nutrition
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