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Barbara Plecko
No abstract text is available yet for this article.
February 2017: Neuropediatrics
Camilla Linder, Katarina Wide, Malin Walander, Olof Beck, Lars L Gustafsson, Anton Pohanka
OBJECTIVES: To investigate if dried blood spots could be used for therapeutic drug monitoring of the antiepileptic drugs, carbamazepine, lamotrigine and valproic acid in children with epilepsy. METHODS: Fingerprick blood samples from 46 children at a neuropediatric outpatient clinic was collected on filterpaper at the same time as capillary plasma sampling. A validated dried blood spot liquid chromatography tandem mass spectrometry method for carbamazepine, lamotrigine and valproic acid was compared with the routine plasma laboratory methods...
December 24, 2016: Clinical Biochemistry
L Ochoa-Gomez, J Lopez-Pison, R Fernando-Martinez, C Fuertes-Rodrigo, P Samper-Villagrasa, L Monge-Galindo, J L Pena-Segura
AIM: A descriptive study of non-symptomatic epilepsy (idiopathic and cryptogenic), according to age at onset, monitored at a Neuropediatric Section of regional reference over a period of three years. PATIENTS AND METHODS: A review of neuropediatric database medical records of children with non-symptomatic epilepsy supervised from Jan 1, 2008 till December 31, 2010. RESULTS: Of the 4595 children attended during the period, 605 were diagnosed with epilepsy (13...
November 16, 2016: Revista de Neurologia
Salome Kornfeld, Martina Studer, Stephanie Winkelbeiner, Mária Regényi, Eugen Boltshauser, Maja Steinlin
AIM: Paediatric arterial ischaemic stroke can lead to reduced quality of life (QoL). It is important to identify predictors of QoL to support recovery. We examined long-term QoL after arterial ischaemic stroke concerning different variables. METHOD: Children registered in the Swiss Neuropediatric Stroke Registry and suffering from arterial ischaemic stroke between 2000 and 2008 were included. Two years post-stroke, assessments included intelligence quotient tests for cognitive impairment and modified Rankin Scale (mRS) for neurological impairment; 5 years post-stroke, the Kidscreen-27 was used for QoL, DSM-IV criteria screening was used for attention deficits, and the ABILHAND-Kids was used for manual motor skills...
October 21, 2016: Developmental Medicine and Child Neurology
Muhammad Mahaj, Rajech Sharkia, Nadeem Shorbaji, Nathanel Zelnik
BACKGROUND: Despite the increased worldwide recognition of attention deficit/hyperactivity disorder (ADHD), there is a variability in the diagnostic rate of both ADHD and its co-morbidities. These diversities are probably related to the methodology and instruments used for the diagnosis of ADHD and to awareness and cultural interpretation of its existence. OBJECTIVES: To identify consistent differences in the clinical profile of Arab and Jewish children with ADHD in Israel who differ in cultural, ethnic and socioeconomic background...
June 2016: Israel Medical Association Journal: IMAJ
U Diaz-Orueta, M A Fernandez-Fernandez, M D Morillo-Rojas, G Climent
INTRODUCTION: Lisdexanfetamine (LDX) is the drug for attention deficit hyperactivity disorder (ADHD) undergoing the largest research volume in the latest years. However, no studies certify its usefulness for the improvement of cognitive functioning in ADHD. AIM: To evaluate the efficacy of LDX in the behavioral and cognitive improvement of a group of patients with ADHD. Such efficacy was measured by means of the administration of AULA Nesplora virtual reality test before the prescription of pharmacological treatment and right after the treatment with LDX...
July 1, 2016: Revista de Neurologia
Abdelrahim Abdrabou Sadek, Montaser Mohamed Mohamed, El-Zahraa El-Said Ahmed Sharaf, Rofaida Mohamed Magdy, Ahmed Ahmed Allam
INTRODUCTION: Breath-holding spells (BHSs) are involuntary pauses of breathing, sometimes accompanied by loss of consciousness. They usually occur in response to an upsetting or surprising situation. Breath-holding spells are usually caused by either a change in the usual breathing pattern or a slowing of the heart rate. In some children, BHSs may be related to iron deficiency anemia. The aim of the work was to study the clinical and laboratory profile of BPHs in children presented to the Neuropediatric Clinic at Sohag University Hospital...
April 2016: Electronic Physician
Stavroula Anastasopoulou, Marie Lindefeldt, Marco Bartocci, Ronny Wickström
BACKGROUND: Acute inflammatory demyelinating polyneuropathy (AIDP), also known as Guillain-Barré syndrome, is an immune-mediated polyneuropathy usually triggered by infections or vaccinations. In childhood AIDP is commonly described after the first year of life. Here, we present a case of a newborn infant with AIDP manifestation directly after delivery. CASE STUDY: A newborn girl with a healthy mother, without known exposure to immunomodulating factors, was admitted to the neuropediatric department due to ascending hypotonia, weakness, pain and areflexia in the lower extremities...
September 2016: European Journal of Paediatric Neurology: EJPN
Sandro M Krieg, Sebastian Sonanini, Nico Sollmann, Axel Focke, Lucia Gerstl, Florian Heinen
Aim For children with medical complexity, interdisciplinary treatment approaches are required to address the various aspects defined within the biopsychosocial model. Methods The present study identifies dimensions of the biopsychosocial model to generate a standardized visualized severity score for chronic neurological diseases in children. We demonstrate the score's applicability and usefulness in clinical practice among clinicians with and without pediatric board certification with the aid of illustrative patient cases...
August 2016: Neuropediatrics
Nicolas Lang, Max Lange, Friedhelm C Schmitt, Monika Bös, Yvonne Weber, Stefan Evers, Lothar Burghaus, Christoph Kellinghaus, Susanne Schubert-Bast, Julian Bösel, Thorsten Lammers, Michael Sabolek, Andreas van Baalen, Rainer Dziewas, Andrea Kraft, Susanne Ruf, Ulrich Stephani
PURPOSE: This non-interventional study was conducted to evaluate the efficacy and tolerability of intravenous lacosamide (LCM-iv) under routine conditions in daily clinical practice as a prospective registry. METHODS: Patients with any type of seizure or epilepsy syndrome were recruited in 16 neurological and neuropediatric centers in Germany if the treating physician decided to administer LCM-iv for any reason. Observation time per patient was 10 days with daily documentation of LCM-iv administration, type and frequency of seizures, currently used drugs and doses, and adverse events...
July 2016: Seizure: the Journal of the British Epilepsy Association
Ulrike Schara, Thomas Lücke
No abstract text is available yet for this article.
April 2016: Neuropediatrics
Corinna N Gerber, Bettina Kunz, Hubertus J A van Hedel
BACKGROUND: Home-based, computer-enhanced therapy of hand and arm function can complement conventional interventions and increase the amount and intensity of training, without interfering too much with family routines. The objective of the present study was to investigate the feasibility and usability of the new portable version of the YouGrabber® system (YouRehab AG, Zurich, Switzerland) in the home setting. METHODS: Fifteen families of children (7 girls, mean age: 11...
March 23, 2016: Journal of Neuroengineering and Rehabilitation
Catherine Mercier, Sylvain Roche, Ségolène Gaillard, Behrouz Kassai, Alexis Arzimanoglou, Vania Herbillon, Pascal Roy, Sylvain Rheims
OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is a well-known comorbidity in children with epilepsy. In English-speaking countries, the scores of the original ADHD-rating scale IV are currently used as main outcomes in various clinical trials in children with epilepsy. In French-speaking countries, several French versions are in use though none has been fully validated yet. We sought here for a partial validation of a French version of the ADHD-RS IV regarding construct validity, internal consistency (i...
May 2016: Epilepsy & Behavior: E&B
Ulrike Schara, Thomas Lücke
No abstract text is available yet for this article.
April 2016: Neuropediatrics
Laura Ochoa-Gomez, Javier Lopez-Pison, Ruth Fernando-Martinez, Cristina Fuertes-Rodrigo, Pilar Samper-Villagrasa, Lorena Monge-Galindo, José Luis Peña-Segura, M Concepción García-Jiménez
AIM: To analyze the factors involved in the prognosis of symptomatic epilepsies in relation to their age at onset, monitored at a neuropediatric section of regional reference over a period of three years. PATIENTS AND METHODS: Children diagnosed with symptomatic epilepsy, supervised from January 1, 2008 to December 31, 2010, collecting epidemiological, clinical and developmental data. RESULTS: Of the 4595 children attended during the period, the diagnosis of epilepsy was established at 605 (13...
March 16, 2016: Revista de Neurologia
J Gordon Millichap
Investigators at University Children's Hospital, Inselspital, and Universities of Bern, Geneva, Basel, and Zurich, Switzerland compared long-term outcome of children (1 month-16 years) and young adults (16.1-45 years) with arterial ischemic stroke (AIS) using prospective data from the Swiss Neuropediatric Stroke Registry and the Adult Bernese stroke registry, between Jan 2000 and Dec 2008.
May 2015: Pediatric neurology briefs
Daniel Tibussek, Jörg Klepper, Rudolf Korinthenberg, Gerhard Kurlemann, Dietz Rating, Gabriele Wohlrab, Markus Wolff, Bernhard Schmitt
Objectives This report aims to define treatment goals, to summarize the evidence level (EL) of different treatment options for infantile spasms (IS), both in terms of efficacy and adverse effect, and to give recommendations for the management of IS. Methods The Cochrane and Medline (1966-July 2014) databases were searched. Literature known to the guideline working group and identified through citations was also considered. The results of previously published guidelines were taken into account in our analysis...
June 2016: Neuropediatrics
Smail Zubcevic, Maja Milos, Feriha Catibusic, Sajra Uzicanin, Belma Krdzalic
INTRODUCTION: Neuroimaging procedures and electroencephalography (EEG) are basic parts of investigation of patients with epilepsies. AIM: The aim is to try to assess relationship between bilaterally localized brain lesions found in routine management of children with newly diagnosed epilepsy and their interictal EEG findings. PATIENTS AND METHODS: Total amount of 68 patients filled criteria for inclusion in the study that was performed at Neuropediatrics Department, Pediatric Hospital, University Clinical Center Sarajevo, or its outpatient clinic...
December 2015: Acta Informatica Medica: AIM
Laura Ochoa-Gómez, Javier López-Pisón, Cristina Fuertes-Rodrigo, Ruth Fernando-Martínez, Pilar Samper-Villagrasa, Lorena Monge-Galindo, José Luis Peña-Segura
AIM: To analyze the factors involved in the prognosis of non-symptomatic epilepsy (idiopathic and cryptogenic) in relation to their age of onset, monitored at a regional section of Neuropediatry reference over a period of three years. PATIENTS AND METHODS: Patients with diagnosis of non-symptomatic epilepsy supervised from January 1, 2008 to December 31, 2010, collecting epidemiological, clinical, complementary examinations and developmental data. RESULTS: Of the 4595 children attended during the period, the diagnosis of epilepsy was established in 605 (13...
February 16, 2016: Revista de Neurologia
Bernd Neubauer, Barbara Plecko, Eugen Boltshauser
No abstract text is available yet for this article.
January 2016: Neuropediatrics
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