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https://www.readbyqxmd.com/read/28934880/three-dimensional-bioprinting-and-its-potential-in-the-field-of-articular-cartilage-regeneration
#1
Vivian H M Mouser, Riccardo Levato, Lawrence J Bonassar, Darryl D D'Lima, Daniel A Grande, Travis J Klein, Daniel B F Saris, Marcy Zenobi-Wong, Debby Gawlitta, Jos Malda
Three-dimensional (3D) bioprinting techniques can be used for the fabrication of personalized, regenerative constructs for tissue repair. The current article provides insight into the potential and opportunities of 3D bioprinting for the fabrication of cartilage regenerative constructs. Although 3D printing is already used in the orthopedic clinic, the shift toward 3D bioprinting has not yet occurred. We believe that this shift will provide an important step forward in the field of cartilage regeneration. Three-dimensional bioprinting techniques allow incorporation of cells and biological cues during the manufacturing process, to generate biologically active implants...
October 2017: Cartilage
https://www.readbyqxmd.com/read/28917520/short-term-complications-in-intra-and-extra-articular-anterior-cruciate-ligament-reconstruction-comparison-with-the-literature-on-isolated-intra-articular-reconstruction-a-multicenter-study-by-the-french-society-of-arthroscopy
#2
J C Panisset, R Pailhé, B Schlaterrer, L Sigwalt, B Sonnery-Cottet, C Lutz, S Lustig, C Batailler, S Bertiaux, F P Ehkirch, P Colombet, C Steltzlen, M L Louis, P D'ingrado, F Dalmay, P Imbert, D Saragaglia
INTRODUCTION: Lateral tenodesis (LT) is performed to limit the risk of iterative tear following anterior cruciate ligament (ACL) reconstruction in at-risk patients. By adding an extra procedure to isolated ACL graft, LT reconstruction increases operating time and may complicate postoperative course. The objective of the present study was to evaluate the rate of early complications. The study hypothesis was that associating ALL reconstruction to ACL reconstruction does not increase the complications rate found with isolated ACL reconstruction...
September 13, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28914855/-late-onset-rheumatoid-arthritis-in-a-patient-with-successfully-treated-iga-nephropathy
#3
N V Chebotareva, I N Bobkova, S V Gulyaev
The paper describes a rare clinical case of rheumatoid arthritis (RA) that developed in a patient 9 years after diagnosing IgA nephropathy. Kidney disease was characterized by a stable course with moderate urinary syndrome, hypertension, and reduced renal function. Immunosuppressive therapy using glucocorticosteroids and then mycophenolic acid led to remission of nephritis and recovery of renal function. However, the absence of nephritis activity and discontinuation of immunosuppressants was responsible for articular syndrome...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28906305/risk-of-knee-sepsis-following-treatment-of-open-tibia-fractures-a-multicenter-comparison-of-suprapatellar-and-infrapatellar-approaches
#4
Geoffrey S Marecek, Luke T Nicholson, Frances H Broghammer, Michael Talerico, Caroline Tougas, Derek J Donegan, John A Scolaro
OBJECTIVES: The suprapatellar approach for medullary nailing of the tibia is increasing. This requires intra-articular passage of instruments, which theoretically places the knee at risk for postoperative sepsis in the setting of open fracture. We hypothesized that the risk of knee sepsis is similar after suprapatellar or infrapatellar nailing of open tibia fractures. DESIGN: Retrospective, multicenter. SETTING: Three urban Level-1 trauma centers PATIENTS:: All patients treated with medullary nailing for open diaphyseal tibia fractures (OTA 42) from 2009 to 2015...
September 11, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28904724/treatment-of-high-energy-pilon-fractures-using-the-ilizarov-treatment
#5
Walid Osman, Zeineb Alaya, Hamdi Kaziz, Lassad Hassini, Meriem Braiki, Nader Naouar, Mohamed Laaziz Ben Ayeche
The management of high-energy pilon fractures is still controversial. Open reduction and internal fixation are often associated with serious complications. Various methods have been used to treat these injuries, with variable results. The aim of this retrospective study was to analyze the clinical and radiographic outcome of the ILIZAROV technique in patients with high-energy pilon fractures. Thirty cases of distal tibia epiphysis fractures (pilon fractures) were managed from 1999 to 2012. The study group included 5 cases of open fractures...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28900671/-wrist-arthrodesis-with-a%C3%A2-fixed-angle-low-profile-fusion-plate-without-carpometacarpal-joint-fixation
#6
REVIEW
S Köhler, K Koch, A Arsalan-Werner, I M Mehling, J Seegmüller, H Krimmer, Michael Sauerbier
OBJECTIVE: Total wrist arthrodesis to improve functional use of the hand by reducing pain and increasing grip strength. INDICATIONS: Painful destruction of the radio- and midcarpal joints. CONTRAINDICATIONS: Analgesia and satisfactory hand function after motion-preserving surgical or conservative treatment. Chronic joint infection. SURGICAL TECHNIQUE: Posterior approach to the wrist. Removal of articular surfaces destroyed all the way down to cancellous bone...
September 12, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28890121/surgical-treatment-of-extra-articular-distal-third-diaphyseal-fractures-of-the-humerus-using-a-modified-posterior-approach-and-an-extra-articular-plate
#7
P Páramo-Díaz, M Arroyo-Hernández, V Rodríguez Vega, M Aroca-Peinado, J L León-Baltasar, P Caba-Doussoux
PURPOSE: To evaluate the clinical and radiological outcomes of these fractures treated through a modified posterior approach with a distal humerus plate. MATERIAL AND METHODS: Between 2013 and 2015 we performed a retrospective study of these fractures surgically treated in our centre. INCLUSION CRITERIA: older than 18 years old, no pathological fractures, follow up 1 year at least. 23 patients underwent surgery, mean age 45 years old, with an average follow-up of 18 months...
September 7, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28884287/incidence-of-comprehensive-hospitalization-due-to-infection-cardiovascular-disease-fractures-and-malignancies-in-patients-with-rheumatoid-arthritis
#8
Naoki Sugimoto, Ayako Nakajima, Eisuke Inoue, Kumi Shidara, Hiroyuki Yamashita, Akio Mimori, Hitoshi Tokuda, Yohei Seto, Eiichi Tanaka, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka
To comprehensively analyze the overall incidence of hospitalization for comorbidities in patients with rheumatoid arthritis (RA). We prospectively analyzed overall hospitalizations for comorbidities using the Institute of Rheumatology, Rheumatoid Arthritis (IORRA) cohort. The incidence of hospitalized comorbidity was calculated. Risk factors for the most frequent hospitalized comorbidities were determined by multivariate logistic regression analysis. Among 5519 RA patients contributing 5336.5 person-years of observation, 435 incidences of hospitalized comorbidity [8...
September 7, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28842229/intraoperative-navigation-is-associated-with-reduced-blood-loss-during-c1-2-posterior-cervical-fixation
#9
Frederick L Hitti, Eric D Hudgins, H Isaac Chen, Neil R Malhotra, Eric L Zager, James M Schuster
OBJECTIVE: Traumatic injuries, degenerative/rheumatologic conditions, tumors, or infections of the upper cervical spine may in certain circumstances require surgical stabilization. C1 lateral mass screws (Harms technique) in combination with C2 instrumentation (pars, pedicle, translaminar screws) have become a mainstay of surgical treatment. The surgical anatomy of the C1 lateral mass can be challenging especially with the robust venous plexus that often causes significant bleeding with exposure of the C1-C2 articular complex...
August 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28837372/update-upon-efficacy-and-safety-of-etanercept-for-the-treatment-of-spondyloarthritis-and-juvenile-idiopathic-arthritis
#10
Giuseppe Murdaca, Simone Negrini, Ottavia Magnani, Elena Penza, Marco Pellecchio, Rossella Gulli, Paola Mandich, Francesco Puppo
TNF-α inhibitors have demonstrated efficacy both as monotherapy and in combination with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of chronic inflammatory immune-mediated diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis (AS), psoriasis (Ps) and/or psoriatic arthritis (PsA) and may be administered off-label to treat disseminated granuloma annulare, systemic lupus erythematosus and systemic sclerosis. There are several TNF-α inhibitors available for clinical use including infliximab, adalimumab, golimumab, certolizumab pegol and etanercept...
August 24, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28826650/evaluation-and-quantification-of-geographical-differences-in-wound-complication-rates-following-the-extended-lateral-approach-in-displaced-intra-articular-calcaneal-fractures-a-systematic-review-of-the-literature
#11
REVIEW
M Backes, K E Spierings, S A Dingemans, J C Goslings, R E Buckley, T Schepers
INTRODUCTION: Calcaneal fracture surgery is often performed via the extended lateral approach (ELA). Large differences are reported in literature on wound complication rates. Aim was to perform a systematic review on reported postoperative wound complication (POWC) and postoperative wound infection (POWI) rates following the ELA and evaluate and quantify geographical differences. METHODS: A literature search was conducted in the MEDLINE and EMBASE databases and Cochrane Library...
August 13, 2017: Injury
https://www.readbyqxmd.com/read/28814102/minimally-invasive-plate-osteosynthesis-using-locking-plates-for-ao-43-type-fractures-lessons-learnt-from-a-prospective-study
#12
Rajeev Shukla, Nikhil Jain, Ravi Kant Jain, Shravan Patidar, Vivek Kiyawat
INTRODUCTION: Managing fractures of distal tibia is still a subject of debate for orthopaedic surgeons in terms of both, reduction and fixation. Subcutaneous location and soft tissue anatomy predisposes it to angular and rotational instability as well as other bony and soft tissue complexities. Minimally invasive plating offers many advantages over conventional open techniques. It causes minimal soft tissue dissection and surgical trauma to the bone. Minimally invasive plate osteosynthesis(MIPO) maintains biological configuration of distal tibia and fracture hematoma and also provides a construct, which is biomechanically more stable...
August 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28811109/the-risk-of-acute-infection-following-intra-articular-corticosteroid-injection-into-a-pre-existing-total-knee-arthroplasty
#13
Emily S Mills, Michael B Elman, Jared R H Foran
BACKGROUND: No previous studies have investigated the risk of infection following intra-articular corticosteroid injection (IACI) into a pre-existing total knee arthroplasty (TKA). The aim of this study is to determine the risk of acute infection following IACI into a pre-existing TKA. METHODS: A retrospective chart review identified all patients at a single institution between October 2009 and May 2015 that had an ipsilateral knee injection subsequent to a TKA...
July 25, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28808949/practical-management-of-respiratory-comorbidities-in-patients-with-rheumatoid-arthritis
#14
REVIEW
James Bluett, Meghna Jani, Deborah P M Symmons
Lung disease is one of the most common causes of extra-articular morbidity and mortality in patients with rheumatoid arthritis (RA). Development of pulmonary manifestations may be due to the systemic disease itself; to serious respiratory adverse events such as pneumonitis and infections secondary to therapy; or to lifestyle habits such as smoking. Rheumatologists often need to make important treatment decisions and plan future care in RA patients with respiratory comorbidities, despite the absence of clear evidence or consensus...
August 14, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/28800918/the-timing-of-hip-arthroscopy-after-intra-articular-hip-injection-affects-postoperative-infection-risk
#15
Dean Wang, Christopher L Camp, Anil S Ranawat, Struan H Coleman, Bryan T Kelly, Brian C Werner
PURPOSE: To evaluate the association of preoperative intra-articular hip injection with surgical site infection after hip arthroscopy. METHODS: A large administrative database was used to identify all patients undergoing hip arthroscopy from 2007 to 2015 within a single private insurer and from 2005 to 2012 within Medicare in the United States. Those that received an ipsilateral preoperative intra-articular hip injection were identified. The patients were then divided into the following groups based on the interval between preoperative injection and ipsilateral hip arthroscopy: (1) <3 months, (2) 3 to 6 months, and (3) 6 to 12 months...
August 8, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28800262/risk-factors-predisposing-to-the-development-of-hypogammaglobulinemia-and-infections-post-rituximab
#16
Evangelos A A Christou, Giuliana Giardino, Austen Worth, Fani Ladomenou
Rituximab (RTX) is a monoclonal antibody against CD20, commonly used in the treatment of hematological malignancies and autoimmune diseases. The use of RTX is related to the development of hypogammaglobulinemia and infections. Aim of this review is to summarize the evidence supporting the association of specific risk factors with the development of hypogammaglobulinemia and infections post-RTX. Immunological complications are more common in patients with malignant diseases as compared to non-malignant diseases...
August 11, 2017: International Reviews of Immunology
https://www.readbyqxmd.com/read/28791884/added-value-of-18f-fdg-pet-ct-in-diagnosing-infected-hip-prosthesis
#17
Robert M Kwee, Wouter Am Broos, Boudewijn Brans, Geert Him Walenkamp, Jan Geurts, René E Weijers
Background The diagnosis of infected hip prosthesis is frequently not straightforward yet very important as it changes treatment. Purpose To retrospectively investigate the added value of 18F-FDG PET/CT to conventional tests including radiography, erythrocyte sedimentation rate (ESR)/C-reactive protein (CRP) testing, and joint aspiration, in diagnosing infected hip prosthesis. Material and Methods Seventy-eight hip prostheses of 78 patients (55% men; mean age = 66.5 years; age range = 30-85 years) with non-specific clinical presentation, i...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28764233/multifocal-tubercular-dactylitis-a-rare-presentation-of-skeletal-tuberculosis-in-an-adult
#18
Pravat Thatoi, Manoj Parida, Rakesh Barik, Bidyut Das
Tubercular dactylitis is an uncommon form of osteo-articular tuberculosis seen in children. Multifocal involvement, simultaneously involving hands and feet is extremely uncommon. Here we report an adult patient with tubercular dactylitis involving multiple digits of both hands and second digit of right foot in absence of any risk factors like immunodeficiency or any debilitating condition. The patient was successfully treated with anti-tubercular drugs for six months. Mycobacterium tuberculosis infection of bones and joints can present in an unusual way but early diagnosis and treatment caries a good prognosis...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763892/-efficacy-and-safety-of-drainage-after-total-knee-arthroplasty
#19
F Jing, H M Li, X D Yang, B Li, J Ji, Y L Li, C J Sun
Objective: To determine whether suction drainage is safe and effective compared with no-drainage in total knee arthroplasty. Methods: The literature search was based on PubMed, MEDLINE, EMBASE, Highwire, the Cochrane Library, CBM, CNKI, VIP and WFSD.The data were analysed using RevMan 5.3.Fourteen randomised controlled trials involving 1 009 knees were included in our analysis. Results: Suction drainage increases the rate and volume of blood transfusion.No-drainage group increases the rate of wound problems (OR=1...
July 18, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28751110/chronic-arthritis-in-chikungunya-virus-infection
#20
Lourdes Mateo, Silvia Roure
INTRODUCTION: Chikungunya virus infection causes arthralgia and arthritis in the acute phase of the disease but, in more than half of the cases, musculoskeletal manifestations can be prolonged over time and, in some cases, become chronic. Although polyarthralgia is the most frequent chronic manifestation, forms with polyarthritis, tenosynovitis and enthesopathy are also common. OBJECTIVE: To analyze the clinical characteristics of patients with persistent articular manifestations after infection with the Chikungunya virus...
July 24, 2017: Reumatología Clinica
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