keyword
https://read.qxmd.com/read/38637221/cretan-hla-genetics-supports-its-early-minoan-culture-as-a-link-between-north-africa-and-europe
#1
JOURNAL ARTICLE
Antonio Arnaiz-Villena, Ignacio Juarez, Christian Vaquero-Yuste, Tomas Lledo, Jose Manuel Martin-Villa, Fabio Suarez-Trujillo
HLA studies in Crete show that this population is related to North Africans and also Iberians. This may be a reflection of a common prehistoric first Europeans relationships with North Africans and drying Saharan emigration after 10,000 years BC; it may be specifically represented by a primitive and early cult to the bull in both Cretan (Minoan) and Iberian populations. In the present study, unrelated Cretans representing different Island parts have been studied for class II HLA-DRB1 and -DQB1 alleles...
April 17, 2024: Human Immunology
https://read.qxmd.com/read/38609348/evaluation-of-sponge-wipe-surface-sampling-for-collection-of-potential-surrogates-for-non-spore-forming-bioterrorism-agents
#2
JOURNAL ARTICLE
L D Aslett, M W Calfee, M Monge, A Abdel-Hady, T Chamberlain, R Baartmans, A Touati
AIM: Evaluate the efficacy of sponge wipe sampling at recovering potential bacterial surrogates for Category A and B non-spore-forming bacterial bioterrorism agents from hard nonporous surfaces. METHODS: A literature survey identified seven nonpathogenic bacteria as potential surrogates for selected Category A and B non-spore-forming bacterial agents. Small (2- by 4-cm) and large (35.6- by 35.6-cm) coupons made from either stainless steel, plastic, or glass, were inoculated and utilized to assess persistence, and surface sampling efficiency, respectively...
April 12, 2024: Journal of Applied Microbiology
https://read.qxmd.com/read/38599803/superstitions-of-composure-the-ayn-rand-cult-and-the-pop-psychology-of-self-esteem
#3
REVIEW
Marie Kolkenbrock
Ayn Rand is known as an advocate of rugged individualism and unregulated capitalism, which has led to a scholarly focus on her influence on neoliberal and right-wing politics. This article focuses on the psychologically unrealistic conceptualisation of self-esteem in Rand's ethics, which arguably prevails in today's self-help culture. Rand endorsed Nathaniel Branden, her acolyte and lover, as official therapist for her circle. In this role, he promoted the positive effects of living according to Randian principles on mental health...
April 11, 2024: BJPsych Bulletin
https://read.qxmd.com/read/38347005/plant-related-philistine-ritual-practices-at-biblical-gath
#4
JOURNAL ARTICLE
Suembikya Frumin, Aren M Maeir, Maria Eniukhina, Amit Dagan, Ehud Weiss
The Philistine culture (Iron Age, ca. 1200-604 BCE) profoundly impacted the southern Levant's cultural history, agronomy, and dietary customs. Nevertheless, our knowledge of the Philistines' cultic praxis and deities, is limited and uncertain. Here, we combine archaeological data with a meticulous study of plant use at two successive temples at Tell eṣ-Ṣâfī/Gath. We provide a list of the plants used, their time of harvest, mode of offering, and possible symbolism. Analysis of the temples' macrobotanical (seed and fruits) plant assemblage reveals the offerings; that the inception date for rites was early spring; and sheds light on the date of the final utilization of the temples (late summer/early fall)...
February 12, 2024: Scientific Reports
https://read.qxmd.com/read/38127467/incidence-factors-and-prognostic-analyses-of-challenging-cardiopulmonary-bypass-separation-in-chinese-cardiac-surgical-populations
#5
JOURNAL ARTICLE
Dong X Chen, Tian H Wang, Xing L Xiong, Jing Shi, Leng Zhou
BACKGROUND: Challenging separation from cardiopulmonary bypass (CPB) has been associated with multiple medical adversities, while its incidence, associated factors, and prognosis among cardiac surgery populations are substantially understudied. METHODS: Adult cardiac surgical patients in two medical centers were retrospectively analyzed. Separation from CPB was stratified as easy, difficult, or complex, based on the use of pharmacologic assistance agents and mechanical supports...
December 21, 2023: Minerva Anestesiologica
https://read.qxmd.com/read/38118178/long-distance-spin-communication-via-ambipolar-conductor-with-electron-hole-spin-exchange-interaction
#6
JOURNAL ARTICLE
Yukihiro Koinuma, Shigehiko Hasegawa, Masamichi Sakai
Spin accumulation in a nonmagnetic (N) metal embedded between two ferromagnetic metals is still crucial in current spintronics because long-distance spin communication via the N metal can make all-spin logic (ASL) devices feasible. Graphen is almost the only N-region material suitable for ASL devices because its low intrinsic spin-orbit coupling results in a spin diffusion length, ΘN, of over 30 μm at room temperature, but long-distance spin communication beyond ΘN remains difficult...
December 20, 2023: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://read.qxmd.com/read/37999015/impact-of-the-tobacco-heating-system-and-cigarette-smoking-on-the-oral-cavity-a-pilot-study
#7
JOURNAL ARTICLE
Ella Sever, Elvis Božac, Ema Saltović, Sunčana Simonić-Kocijan, Martina Brumini, Irena Glažar
Cigarette smoking and the harmful chemicals released during smoking have negative effects on oral health. As a measure of harm reduction, a new alternative tobacco heating system (THS) has been developed. The aim of the study was to analyze and compare the effects of conventional cigarettes and THS on the oral mucosa, the salivary flow rate (SFR), halitosis, and the load of Candida spp. The study included 20 tobacco heating smokers, 20 conventional cigarette smokers, and 20 nonsmokers. The subjects completed questionnaires on medical information, smoking habits, oral lesions, and symptoms...
October 27, 2023: Dentistry Journal
https://read.qxmd.com/read/37998433/the-ethics-of-ancient-lactation-and-the-cult-of-the-perfect-breastfeeding-mother
#8
JOURNAL ARTICLE
Elisa Groff, Florian Steger
Breastfeeding is a key issue found in ancient sources that resonates with public debates today, affecting women in different parts of the world and of all social classes. The aim of this research was to identify breastfeeding narratives in ancient medical and philosophical texts from the 1st to the 6th century CE that address ethical issues in the medical management and social perception of new mothers. We examined 15 literary sources and one funerary inscription on lactation and critically evaluated the ancient idea of the perfect breastfeeding mother versus the non-breastfeeding mother...
November 10, 2023: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/37957295/weaving-deceptive-webs-and-untangling-emotional-truths
#9
JOURNAL ARTICLE
Stan Case
This paper explores how the allure of magical thinking and groupthink contrasts with intuition of emotional truth. Since truth can terrify, the author suggests that a longer learning curve is needed to apprehend what Bion (1970a) called the "evolving O" of the analytic session. Traumatized patients are described as dream weavers who spin webs of partial truths and lies around their true selves. For the analyst, untangling these webs involves what Bion (1970b) calls an "act of faith." Clinical material is presented to show how groupthink and other concretions of thought can, under favorable circumstances, be transformed on the wings of psychic truth...
November 13, 2023: American Journal of Psychoanalysis
https://read.qxmd.com/read/37919826/a-classification-of-combined-homicide-suicide-an-update-part-iii-extrafamilial-homicide-suicide
#10
JOURNAL ARTICLE
Alan R Felthous, Yasir Masood, Delavar Safari, Emily Rodgers, Navreet Chennu, Chanchal Kahlon, Mary Angly
The subclassification of homicide-suicide into psychopathology and intrafamilial homicide-suicides having been presented in the foregoing Parts I and II, this Part III concerns extrafamilial homicide-suicides. Extrafamilial homicide-suicides are divided into adversarial, autogenic mass, cult, and terrorist homicide-suicides. Adversarial homicide-suicides involve a "formal" relationship between actor and homicide victims, further divided according to the role of the actor in their relationship as employee, current or former pupil/student as in school shootings, patient, and litigant...
November 2, 2023: Journal of Forensic Sciences
https://read.qxmd.com/read/37898498/novel-method-for-detecting-the-stage-of-arthrosis-and-femoroacetabular-impingement-using-a-gyroscopic-sensor-and-neural-networks
#11
JOURNAL ARTICLE
P Holeka, F Studnička, J Štěpán, J Matyska, J Šlégr, J Páral, K Šmejkal, P Lochman
PURPOSE OF THE STUDY Femoroacetabular impingement syndrome is a complex, often post-traumatically developing impairment of the hip joint, characterized by ambiguous symptomatology, which makes early diagnosis diffi cult, especially in the early stages. Experimental retrospective study was carried out to evaluate the usability of a triaxial gyroscopic sensor in routine practice as an additional indication criterion for operative versus conservative treatment procedures. MATERIAL AND METHODS 92 patients were included in the retrospective study, and 62 completed the investigation...
2023: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://read.qxmd.com/read/37779627/being-in-between-exploring-former-cult-members-experiences-of-an-acculturation-process-using-the-cultural-formulation-interview-dsm-5
#12
JOURNAL ARTICLE
Cecilia Hadding, Olof Semb, Arja Lehti, Martin Fahlström, Mikael Sandlund, Valerie DeMarinis
OBJECTIVE: To explore the experiences of acculturation into secular Swedish society of former members of cults, with particular focus on mental health, needs and resources. DESIGN: Qualitative method using the Cultural Formulation Interview (CFI) from the DSM-5 as an interview guide. Analysis of participants' experiences of acculturation through systematic text condensation. PARTICIPANTS: Eleven Swedish former members of ideological or religion-based cults...
2023: Frontiers in Psychiatry
https://read.qxmd.com/read/37778706/holy-medicine-patron-saints-of-wounds-due-to-animal-bites
#13
JOURNAL ARTICLE
Agnieszka Polak, Edyta Chomentowska, Andrzej Grzybowski
The cult (system of religious beliefs and rituals) of saints in Western Europe appeared in the 3rd century AD and gained momentum from the 4th to the 6th centuries. Its importance for the European society in the Late Antiquity and the early Middle Ages was undeniable; the holy medicine was the only hope for the sick people because the number of physicians was insufficient and usually physicians were helpless in the face of most the ailments that plagued society at that time. The number of saints had increased over the years, and people sought medical help from them through prayer and other religious practices...
September 29, 2023: Clinics in Dermatology
https://read.qxmd.com/read/37741785/use-of-adipose-derived-stem-cells%C3%A2-accelerates-the-healing-process-in-third-degree-burns
#14
JOURNAL ARTICLE
Maisa Ribeiro, Kamylla Caroline Santos, Mathias Rezende Macedo, Gustavo Albertini de Souza, Francisco Inácio de Assis Neto, Gustavo Henrique Marques Araujo, Dhara Rodrigues Cavalcante, Flavia Ferreira Costa, Gabriel de Sá Ferreira, Larissa Alves Peixoto, Júlia de Miranda Moraes, Valcinir Aloísio Scalla Vulcani
INTRODUCTION: Burns are defined as a traumatic injury, usually of thermal origin, that affects the epithelial and adjacent tissue and is classified according to the depth reached. Tissue repair involved in this type of injury is often a challenge both due to its severity and the multiplicity of complications. Regenerative medicine has focused on the use of low-level laser photobiomodulation therapy (LLLT) and adipose-derived stem cells (ADSC), especially in the early stages of the process, to promote better healing and shorten repair time...
September 9, 2023: Burns
https://read.qxmd.com/read/37652058/boundary-delineation-in-transrectal-ultrasound-images-for-region-of-interest-of-prostate
#15
JOURNAL ARTICLE
Tao Peng, Yan Dong, Gongye Di, Jing Zhao, Tian Li, Ge Ren, Lei Zhang, Jing Cai
Accurate and robust prostate segmentation in transrectal ultrasound (TRUS) images is of great interest for ultrasound-guided brachytherapy for prostate cancer. However, the current practice of manual segmentation is difficult, time-consuming, and prone to errors. To overcome these challenges, we developed an accurate prostate segmentation framework (A-ProSeg) for TRUS images. The proposed segmentation method includes three innovation steps: (1) acquiring the sequence of vertices by using an improved polygonal segment-based method with a small number of radiologist-defined seed points as prior points; (2) establishing an optimal machine learning-based method by using the improved evolutionary neural network; and (3) obtaining smooth contours of the prostate region of interest using the optimized machine learning-based method...
August 31, 2023: Physics in Medicine and Biology
https://read.qxmd.com/read/37619538/a-piecewise-spline-approach-for-modeling-of-ecg-signals
#16
JOURNAL ARTICLE
Alka Mishra, Surekha Bhusnur
This paper presents a new spline-based modeling method of electrocardiogram
(ECG) signal that can reproduce normal as well as abnormal ECG beats. Large
volume ECG data is required for automatic machine learning diagnostic systems, medical
education, research and testing purposes but due to privacy issues, access to this
medical data is very di cult. Given this, modeling an ECG signal is a very challenging
task in the eld of biomedical signal processing. Spline-based modeling is the latest
and one of the most e cient methods with very low computational complexity in the
domain of ECG signal generation...
August 24, 2023: Biomedical Physics & Engineering Express
https://read.qxmd.com/read/37563848/medicinal-chemistry-perspectives-on-recent-advances-in-src-kinase-inhibitors-as-a-potential-target-for-the-development-of-anticancer-agents-biological-profile-selectivity-structure-activity-relationship
#17
JOURNAL ARTICLE
Ghanshyam Teli, Rohit Pal, Lalmohan Maji, Sindhuja Sengupta, Nulgumnalli Manjunathaiah Raghavendra, Gurubasavaraja Swamy Purawarga Matada
The physiological Src proto-oncogene is a protein tyrosine kinase receptor that served as the essential signalling pathway in different types of cancer. The etiology of cancer involved various signalling pathways and Src signalling pathways are also involved in those clusters. Although the dysregulation of Src kinase resulted in cancer being discovered in the late 19th century it is still considered a cult pathway because it is not much explored by different medicinal chemists and oncologists. In this review, we have elaborated about the structure and activation of Src kinase, as well as the development of Src kinase inhibitors...
August 10, 2023: Chemistry & Biodiversity
https://read.qxmd.com/read/37538231/efficacy-of-artificial-oocyte-activation-in-improving-the-reproductive-outcome-in-poor-responders-a-single-centre-cohort-study
#18
JOURNAL ARTICLE
Balpreet Kaur, Sonia Malik, Ved Prakash, Vandana Bhatia, Deepu Gupta
OBJECTIVE: Achieving pregnancy in poor ovarian response patients is a challenge. Failed fertilization after ICSI, despite normal semen parameters is due to defects in oocyte activation. In-vitro activation of oocytes using Ca+2 agents can be useful in increasing the fertilization rates in these patients. This study aimed to evaluate the efficacy of artificial oocyte activation by calcium ionophores in poor responders in improving fertilization, cleavage, implantation and clinical pregnancy rates...
March 2023: Journal of Family & Reproductive Health
https://read.qxmd.com/read/37314119/infliximab-induced-psoriasis-in-an-ulcerative-colitis-patient-successfully-treated-with-guselkumab
#19
JOURNAL ARTICLE
Cong Dai, Yu-Hong Huang
Ulcerative colitis (UC) is a chronic inflammatory disorder of the gastrointestinal tract. Tumor necrosis factor (TNF) inhibitors such as infliximab (IFX) are used to treat UC. But TNF inhibitors can induce psoriasis, which was characterized by IL-17/IL-22 expressing Th17 cells and IFN-γ expressing Th1 cells, with increased expression of Th17 cells correlated with more severe skin lesions and a need for Ustekinumab (UST) therapy1. UST is a monoclonal antibody that binds to the p40 subunit of the interleukin (IL)-12 and IL-23...
June 14, 2023: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/37144746/explanatory-review-on-pyrimidine-fused-pyrimidine-derivatives-as-anticancer-agents-targeting-src-kinase
#20
REVIEW
Ghanshyam Teli, Rohit Pal, Lalmohan Maji, Gurubasavaraja Swamy Purawarga Matada, Sindhuja Sengupta
The pyrimidine and fused pyrimidine ring systems play vital roles to inhibit the c-Src kinase. The Src kinase is made of different domains but the kinase domain is responsible for inhibition of Src kinase. In which the kinase domain is the main domain that is made of several amino acids. The Src kinase is inhibited by its inhibitors when it is activated by phosphorylation. Although dysregulation of Src kinase caused cancer in the late nineteenth century, medicinal chemists have not explored it extensively; therefore it is still regarded as a cult pathway...
May 5, 2023: Journal of Biomolecular Structure & Dynamics
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