keyword
MENU ▼
Read by QxMD icon Read
search

Postmenopausal

keyword
https://www.readbyqxmd.com/read/28944985/ultrasound-characteristics-of-endometrial-cancer-as-defined-by-the-international-endometrial-tumor-analysis-ieta-consensus-nomenclature-a-prospective-multicenter-study
#1
Elisabeth Epstein, Daniela Fischerova, Lil Valentin, Antonia Carla Testa, Dorella Franchi, Povilas Sladkevicius, Frühauf Filip, Pelle G Lindqvist, Floriana Mascilini, Robert Fruscio, Lucia Anna Haak, Gina Opolskiene, Maria Angela Pascual, Juan Luis Alcazar, Valentina Chiappa, Stefano Guerriero, Joseph Carlson, Caroline Van Holsbeke, Francesco Paolo Giuseppe Leone, Bart De Moor, Tom Bourne, Ben van Calster, Arnaud Installe, Dirk Timmerman, Jan Y Verbakel, Thierry Van den Bosch
OBJECTIVES: To describe the sonographic features of endometrial cancer in relation to stage, grade, and histological type using the International Endometrial Tumor Analysis (IETA) terminology. METHODS: Prospective multicenter study on 1714 women with endometrial cancer undergoing a standardized transvaginal grayscale and Doppler ultrasound examination by an experienced ultrasound examiner using a high-end ultrasound system. Clinical and sonographic data were entered into a web-based protocol...
September 25, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28944165/sleep-trajectories-before-and-after-the-final-menstrual-period-in-the-study-of-women-s-health-across-the-nation-swan
#2
Howard M Kravitz, Imke Janssen, Joyce T Bromberger, Karen A Matthews, Martica H Hall, Kristine Ruppert, Hadine Joffe
PURPOSE OF REVIEW: Longitudinal studies show that the menopausal transition (MT) is associated with poorer self-reported sleep. Increases in sleep disturbances across and beyond the MT are strongly associated with vasomotor symptoms (VMS) but occur even without VMS. We analyzed data from baseline through 13 annual or biennial follow-up assessments from SWAN's multi-racial/ethnic cohort of midlife women, specifically focusing on patterns of sleep problems in the years preceding and following the final menstrual period (FMP)...
September 2017: Current Sleep Medicine Reports
https://www.readbyqxmd.com/read/28943183/quantitative-ultrasound-of-the-mandible-as-a-novel-screening-approach-for-osteoporosis
#3
Anna Beattie, Seán Cournane, Ciarán Finucane, J Bernard Walsh, Leo F A Stassen
This study used an axial transmission quantitative ultrasound (QUS) device to assess mandibular bone strength. The aim of the study was first to establish the precision and repeatability of the axial transmission QUS measurement for a range of mandibular anatomic sites, and second to investigate the ability of the modality to differentiate between osteoporotic subjects and a control group. Three groups of adult Caucasian women were recruited: (1) healthy premenopausal women (n = 26), (2) healthy postmenopausal women (n = 48), and (3) women with osteoporosis (n = 53)...
September 21, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28941826/icp-drc-ms-analysis-of-serum-essential-and-toxic-element-levels-in-postmenopausal-prediabetic-women-in-relation-to-glycemic-control-markers
#4
Margarita G Skalnaya, Anatoly V Skalny, Eugeny P Serebryansky, Vasily V Yurasov, Anastasia A Skalnaya, Alexey A Tinkov
PURPOSE: Assessment of the influence of prediabetes on serum trace element and electrolyte levels in postmenopausal women. METHODS: A total of 80 prediabetic and 80 healthy postmenopausal women took part in the present study. Serum was analyzed for glucose, insulin, insulin resistance index (HOMA-IR), total cholesterol (TC), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase (GGT). Glycated haemoglobin (HbA1c) levels were also assessed...
September 14, 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28939589/metabolic-obesity-phenotypes-and-risk-of-breast-cancer-in-postmenopausal-women
#5
Geoffrey C Kabat, Mimi Y Kim, Jennifer S Lee, Gloria Y Ho, Scott B Going, Jennifer Beebe-Dimmer, JoAnn E Manson, Rowan T Chlebowski, Thomas E Rohan
BACKGROUND: Obesity and the metabolic syndrome (MetS) have both been linked to increased risk of postmenopausal breast cancer; however, their relative contributions are poorly understood. METHODS: We examined the association of metabolic phenotypes of obesity defined by presence of the MetS (yes, no) and body mass index (normal, overweight, obese) with risk of postmenopausal breast cancer in a prospective analysis of a cohort of postmenopausal women (n ~ 21,000) with baseline measurements of blood glucose, triglycerides, HDL-cholesterol, blood pressure, waist circumference, and body mass index...
September 22, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28938710/hormone-therapy-use-and-risk-of-chronic-disease-in-the-nurses-health-study-a-comparative-analysis-with-the-women-s-health-initiative
#6
Shilpa N Bhupathiraju, Francine Grodstein, Bernard A Rosner, Meir J Stampfer, Frank B Hu, Walter C Willett, JoAnn E Manson
Observational studies and randomized controlled trials of menopausal hormone therapy (HT) and chronic disease risk appear to have divergent results for cardiovascular disease. However, differences may be related to a modifying effect of age, time since menopause, and HT formulation. In the Nurses' Health Study (NHS) (enrolling during 1980-1994 and following participants until 2002), we investigated associations between the use of oral conjugated equine estrogens (CEE) (0.625 mg/day) plus medroxyprogesterone acetate (MPA) (<10 mg/day) or oral CEE alone and cardiovascular disease, cancer, all-cause mortality, and other major endpoints among postmenopausal women, aged 50-79 years at HT initiation...
September 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28938684/efficacy-and-safety-of-everolimus-in-chinese-metastatic-hr-positive-her2-negative-breast-cancer-patients-a-real-world-retrospective-study
#7
Chengcheng Gong, Yannan Zhao, Biyun Wang, Xichun Hu, Zhonghua Wang, Jian Zhang, Sheng Zhang
BACKGROUND: Everolimus combined with endocrine therapy has been proved to be effective among postmenopausal women with hormone receptor-positive human epidermal growth factor receptor-2 negative (HR+/HER2-) metastatic breast cancer (MBC). We aimed to evaluate the efficacy and safety of everolimus plus endocrine therapy in Chinese real-world practice for the first time, and investigate factors associated with efficacy. METHODS: Seventy-five HR+/HER2- MBC patients were included in this retrospective study who received everolimus plus endocrine therapy after progression on prior endocrine therapy in Fudan University Shanghai Cancer Center (FUSCC) between June 2013 and February 2016...
August 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/28938457/the-association-of-estrogen-receptor-%C3%AE-gene-variation-with-salt-sensitive-blood-pressure
#8
Worapaka Manosroi, Jia Wei Tan, Chevon M Rariy, Bei Sun, Mark O Goodarzi, Aditi R Saxena, Jonathan S Williams, Luminita H Pojoga, Jessica Lasky-Su, Jinrui Cui, Xiuqing Guo, Kent D Taylor, Yii-Der I Chen, Anny H Xiang, Willa A Hsueh, Leslie J Raffel, Thomas A Buchanan, Jerome I Rotter, Gordon H Williams, Ellen W Seely
Context: Hypertension in young women is uncommon compared to young men and older women. Estrogen appears to protect most women against hypertension with incidence increasing after menopause. Since some premenopausal women develop hypertension, estrogen may play a different role in these women. Genetic variations in the estrogen receptor (ER) are associated with cardiovascular disease. ER-β, encoded by ESR2, is the ER predominantly expressed in vascular smooth muscle. Objective: To determine an association of single nucleotide polymorphisms (SNPs) in ESR2 with salt-sensitivity of blood pressure (SSBP) and estrogen status in women...
September 5, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28938270/bariatric-surgery-and-the-risk-of-cancer-in-a-large-multisite-cohort
#9
Daniel P Schauer, Heather Spencer Feigelson, Corinna Koebnick, Bette Caan, Sheila Weinmann, Anthony C Leonard, J David Powers, Panduranga R Yenumula, David E Arterburn
OBJECTIVE: To determine whether bariatric surgery is associated with a lower risk of cancer. BACKGROUND: Obesity is strongly associated with many types of cancer. Few studies have examined the relationship between bariatric surgery and cancer risk. METHODS: We conducted a retrospective cohort study of patients undergoing bariatric surgery between 2005 and 2012 with follow-up through 2014 using data from a large integrated health insurance and care delivery systems with 5 study sites...
September 21, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28937963/ki67-and-lymphocytes-in-the-pretherapeutic-core-biopsy-of-primary-invasive-breast-cancer-positive-markers-of-therapy-response-prediction-and-superior-survival
#10
REVIEW
Claus M Schlotter, Lothar Tietze, Ulf Vogt, Carlos Villena Heinsen, Antje Hahn
Background Core needle biopsy plays a crucial role as diagnostic tool for BC. Both Ki67 and likely tumor-infiltrating lymphocytes (TILs) in the near future are determining the kind of systemic therapy. The role of TILs in BC is still an issue for clinical research, albeit preliminary results of neoadjuvant and adjuvant clinical studies already now highlight the crucial impact of TILs on therapy response and survival. Methods Evaluation of related publications (pubmed) and meeting abstracts (ASCO, SABCS). Results The monoclonal antibody Ki67 recognizing a nuclear antigene in proliferating cells is a positive marker of therapy response and superior survival...
September 22, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28937311/it-s-not-as-bad-as-you-think-menopausal-representations-are-more-positive-in-postmenopausal-women
#11
Lydia Brown, Valerie Brown, Fiona Judd, Christina Bryant
INTRODUCTION: The menopausal transition is associated with underlying hormonal changes that can contribute to a range of physical and emotional symptoms. Psycho-social factors including attitudes and internal representations play a central role in women's experience of the menopause, but very little is known about how representations might differ across menopausal stages. METHODS: A sample of 387 women aged 40-60 completed a postal questionnaire that included the menopausal representations questionnaire, the emotional representation subscale adapted from the illness perception questionnaire, and data on menopausal status...
September 22, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28937289/the-association-of-hyperuricemia-and-metabolic-syndrome-in-thai-postmenopausal-women
#12
K Techatraisak, T Kongkaew
OBJECTIVE: The purpose of this study was to evaluate the association of hyperuricemia and metabolic syndrome (MS) in Thai postmenopausal women. METHODS: A total of 740 consecutive Thai postmenopausal women were reviewed who were not receiving uric acid or lipid-lowering agents at the Menopause Clinic, Faculty of Medicine Siriraj Hospital, Bangkok, from January 2004 to January 2016. Hyperuricemia was defined as serum uric acid level >5.7 mg/dl. The revised National Cholesterol Education Program (rNCEP) 2004 criteria were used for diagnosis of MS...
September 22, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28936598/the-impact-of-the-new-national-bone-health-alliance-nbha-diagnostic-criteria-on-the-prevalence-of-osteoporosis-in-the-united-states-supplementary-presentation
#13
N C Wright, K G Saag, B Dawson-Hughes, S Khosla, E S Siris
We evaluated the prevalence of osteoporosis using the osteoporosis diagnostic criteria developed by the National Bone Health Alliance (NBHA), which includes qualified fractures, FRAX score in addition to BMD. The expanded definition increases the prevalence compared to BMD alone definitions; however, it may better identify those at elevated fracture risk. Recently an NBHA working Group published a paper in OI with recommendations for expanding the criteria that would constitute an osteoporosis diagnosis in postmenopausal women and in men over age 50 for use in the US - Siris et al...
September 21, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28936482/menopause-and-ischemic-stroke-a-brief-review
#14
Shashank Shekhar, Olivia K Travis, Xiaochen He, Richard J Roman, Fan Fan
Ischemic stroke is one of the leading causes of morbidity and mortality worldwide. Females are protected against stroke before the onset of menopause. Menopause results in increased incidence of stroke when compared to men. The mechanisms of these differences remain to be elucidated. Considering that there is a postmenopausal phenomenon and females in general, are living longer sex hormone-dependent mechanisms have been postulated to be the primary factors responsible for the premenopausal protection from stroke and later to be responsible for the higher incidence and increased the severity of stroke after menopause...
2017: MOJ Toxicol
https://www.readbyqxmd.com/read/28935141/antioxidative-peptide-from-milk-exhibits-antiosteopenic-effects-through-inhibition-of-oxidative-damage-and-bone-resorbing-cytokines-in-ovariectomized-rats
#15
Sanusi Bello Mada, Srinu Reddi, Naveen Kumar, Rohit Kumar, Suman Kapila, Rajeev Kapila, Ritu Trivedi, Anirudha Karvande, Naseer Ahmad
OBJECTIVES: Oxidative stress has been implicated as a crucial pathogenic factor in the development of postmenopausal osteoporosis. Milk-derived antioxidative peptides are gaining much attention toward the development of prodrugs for alleviating several human diseases, including osteoporosis. The aim of the present study was to determine whether antioxidant peptides are good candidates for alleviating postmenopausal osteoporosis. METHODS: In the present study, an ovariectomized (OVX) osteoporotic rat model was used to investigate the protective effects of buffalo milk casein-derived novel peptide VLPVPQK (PEP) against OVX-induced bone loss and the related mechanisms...
November 2017: Nutrition
https://www.readbyqxmd.com/read/28934233/cardiovascular-disease-and-mortality-after-breast-cancer-in-postmenopausal-women-results-from-the-women-s-health-initiative
#16
Na-Jin Park, Yuefang Chang, Catherine Bender, Yvette Conley, Rowan T Chlebowski, G J van Londen, Randi Foraker, Sylvia Wassertheil-Smoller, Marcia L Stefanick, Lewis H Kuller
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among older postmenopausal women. The impact of postmenopausal breast cancer on CVD for older women is uncertain. We hypothesized that older postmenopausal women with breast cancer would be at a higher risk of CVD than similar aged women without breast cancer and that CVD would be a major contributor to the subsequent morbidity and mortality. METHODS: In a prospective Women's Health Initiative study, incident CVD events and total and cause-specific death rates were compared between postmenopausal women with (n = 4,340) and without (n = 97,576) incident invasive breast cancer over 10 years post-diagnosis, stratified by 3 age groups (50-59, 60-69, and 70-79)...
2017: PloS One
https://www.readbyqxmd.com/read/28933961/17%C3%AE-estradiol-induces-proliferation-of-endometrial-nk-cells-cd56-in-postmenopausal-women
#17
T Sho, T Hachisuga, C Koi, T Kurita, S Kagami, T Kawagoe, Y Matsuura, K Yoshimura, M Hisaoka
OBJECTIVE: The aim of this report was to evaluate the impact of hormone replacement therapy (HRT) on lymphocytic infiltration of the endometrium in postmenopausal women. METHOD: This study included 58 Japanese patients who had undergone hysterectomy at the University Hospital of Occupational and Environmental Health, Japan. Before surgery, nine patients had received 17β-estradiol (E2), 0.72 mg transdermally for 2-8 weeks (E2 group); 16 patients had received an Estra-1,3,5(10)-triene-3,16α, 17β-triol (E3) vaginal tablet 0...
September 21, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28933583/sleep-duration-and-risk-of-liver-cancer-in-postmenopausal-women-the-women-s-health-initiative-study
#18
Kathryn E Royse, Hashem B El-Serag, Liang Chen, Donna L White, Lauren Hale, Haleh Sangi-Haghpeykar, Li Jiao
BACKGROUND: Sleep duration has been associated with nonalcoholic fatty liver disease, but its association with liver cancer remains unknown. MATERIAL AND METHODS: In the prospective Women's Health Initiative Study, 139,368 postmenopausal women reported sleep habits at baseline (1993-1998). We ascertained 175 incident liver cancer cases during an average 13.8 years of follow-up through August 2014. We used multivariable Cox proportional hazard regression models to estimate a hazard ratio (HR) and its 95% confidence interval (95% CI) for risk of liver cancer in association with nocturnal sleep duration...
September 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28933035/expression-profiling-of-micrornas-in-human-bone-tissue-from-postmenopausal-women
#19
Laura De-Ugarte, Jenny Serra-Vinardell, Lara Nonell, Susana Balcells, Magdalena Arnal, Xavier Nogues, Leonardo Mellibovsky, Daniel Grinberg, Adolfo Diez-Perez, Natalia Garcia-Giralt
Bone tissue is composed of several cell types, which express their own microRNAs (miRNAs) that will play a role in cell function. The set of total miRNAs expressed in all cell types configures the specific signature of the bone tissue in one physiological condition. The aim of this study was to explore the miRNA expression profile of bone tissue from postmenopausal women. Tissue was obtained from trabecular bone and was analyzed in fresh conditions (n = 6). Primary osteoblasts were also obtained from trabecular bone (n = 4) and human osteoclasts were obtained from monocyte precursors after in vitro differentiation (n = 5)...
September 20, 2017: Human Cell
https://www.readbyqxmd.com/read/28931999/the-impact-of-closed-versus-open-kinetic-chain-exercises-on-osteoporotic-femur-neck-and-risk-of-fall-in-postmenopausal-women
#20
Ali Abd El-Monsif Thabet, Mansour Abdullah Alshehri, Omar Farouk Helal, Bassem Refaat
[Purpose] This study aimed to investigate how closed and open kinetic chain exercises differed in their impact on bone mineral density (BMD) and fall risk in postmenopausal women with osteoporosis. [Subjects and Methods] The research sample consisted of 40 postmenopausal women with osteoporosis with ages between 51 and 58 years old. They were divided at random into two groups of 20 each, respectively receiving closed and open kinetic chain exercises. These exercises were administered three times per week over a period of four sequential months...
September 2017: Journal of Physical Therapy Science
keyword
keyword
17661
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"