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https://www.readbyqxmd.com/read/28822231/preoperative-halo-gravity-traction-for-severe-thoracic-kyphoscoliosis-patients-from-tibet-radiographic-correction-pulmonary-function-improvement-nursing-and-complications
#1
Xiaojin Li, Liwen Zeng, Xiaoyin Li, Xuexia Chen, Caixia Ke
BACKGROUND This study investigated the outcomes of preoperative HGT as an adjunct treatment for severe thoracic kyphoscoliosis, its role in radiographic correction, and pulmonary function improvement, together with nursing strategy and incidence of complications. MATERIAL AND METHODS Eleven patients with a mean age of 18.8 years were retrospectively reviewed. Inclusion criteria were: patients with severe kyphoscoliosis (coronal Cobb angle and kyphosis angle ≥80°); duration of HGT ≥8 weeks; patients undergoing HGT for at least 12 h per day; traction weight no less than 40% of body weight; and patients not receiving physical therapies...
August 19, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28822056/patient-reported-outcomes-in-myelodysplastic-syndromes-and-mds-mpn-overlap-syndromes-stepping-onto-the-stage-with-changing-times
#2
REVIEW
Sagar S Patel, Aaron T Gerds
Quality of life (QOL) and symptom burden are important measures captured by patient-reported outcomes (PROs). Myelodysplastic and myelodysplastic/myeloproliferative (MDS/MPN) neoplasm overlap syndromes are notable for significant morbidity and mortality, including a wide spectrum of physical and psychosocial effects. Thus, the development and application of PROs can provide meaningful information to facilitate communication and assist in follow up care. Disease-specific measures can more accurately reflect the full breadth of functional restrictions and symptoms...
August 18, 2017: Current Hematologic Malignancy Reports
https://www.readbyqxmd.com/read/28821747/the-integration-of-g%C3%AE-and-mapk-signaling-cascade-in-zygote-development
#3
Guo-Liang Yuan, Hong-Ju Li, Wei-Cai Yang
Cells respond to many signals with a limited number of signaling components. Heterotrimeric G proteins and MAPK cascades are universally used by eukaryotic cells to transduce signals in various developmental processes or stress responses by activating different effectors. MAPK cascade is integrated with G proteins by scaffold protein during plant immunity. However, the molecular relationship between G proteins and MAPK modules in plant development is still unclear. In this study, we demonstrate that Arabidopsis Gβ protein AGB1 interacts with MPK3 and 6, MKK4 and 5, as well as the regulatory domains of YODA (YDA), the upstream MEKK of MKK4/5...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821674/how-auditory-experience-differentially-influences-the-function-of-left-and-right-superior-temporal-cortices
#4
Tae Twomey, Dafydd Waters, Cathy J Price, Samuel Evans, Mairéad MacSweeney
To investigate how hearing status, sign language experience and task demands influence functional responses in the human superior temporal cortices (STC) we collected fMRI data from deaf and hearing participants (male and female), who either acquired sign language early or late in life. Our stimuli in all tasks were pictures of objects. We varied the linguistic and visuospatial processing demands in three different tasks that involved decisions about (1) the sublexical (phonological) structure of the British Sign Language (BSL) signs for the objects; (2) the semantic category of the objects; and (3) the physical features of the objects...
August 18, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28821632/transcriptomic-and-epigenetic-regulation-of-disuse-atrophy-and-the-return-to-activity-in-skeletal-muscle
#5
Andrew G Fisher, Robert A Seaborne, Thomas M Hughes, Alex Gutteridge, Claire Stewart, Judy M Coulson, Adam P Sharples, Jonathan C Jarvis
Physical inactivity and disuse are major contributors to age-related muscle loss. Denervation of skeletal muscle has been previously used as a model with which to investigate muscle atrophy following disuse. Although gene regulatory networks that control skeletal muscle atrophy after denervation have been established, the transcriptome in response to the recovery of muscle after disuse and the associated epigenetic mechanisms that may function to modulate gene expression during skeletal muscle atrophy or recovery have yet to be investigated...
August 17, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28821616/cox16-protein-is-physically-associated-with-cox1p-assembly-intermediates-and-with-cytochrome-oxidase
#6
Chen Hsien Su, Alexander Tzagoloff
Mitochondrial cytochrome oxidase (COX) catalyzes the last step in the respiratory pathway. In Saccharomyces cervisiae this inner membrane complex is composed of 11 protein subunits. Expression of COX is assisted by some 2 dozen ancillary proteins that intercede at different stages of the assembly pathway. One such protein, Cox16p, encoded by COX16, was shown to be essential for activity and assembly of COX. The function of Cox16p, however, has not been determined. We present evidence that Cox16p is present in Cox1p assembly intermediates and in COX...
August 16, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28821518/validation-of-days-at-home-as-an-outcome-measure-after-surgery-a-prospective-cohort-study-in-australia
#7
Paul S Myles, Mark A Shulman, Stephane Heritier, Sophie Wallace, David R McIlroy, Stuart McCluskey, Isabella Sillar, Andrew Forbes
OBJECTIVE: To evaluate 'days at home up to 30 days after surgery' (DAH30) as a patient-centred outcome measure. DESIGN: Prospective cohort study. DATA SOURCE: Using clinical trial data (seven trials, 2109 patients) we calculated DAH30 from length of stay, readmission, discharge destination and death up to 30 days after surgery. MAIN OUTCOME: The association between DAH30 and serious complications after surgery. RESULTS: One or more complications occurred in 263 of 1846 (14...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28820970/utility-of-the-comprehensive-marijuana-motives-questionnaire-among-medical-cannabis-patients
#8
Kipling M Bohnert, Erin E Bonar, J Todd Arnedt, Deirdre A Conroy, Maureen A Walton, Mark A Ilgen
BACKGROUND: Little is known about motives for cannabis use among the population of adults using cannabis medically. Therefore, we evaluated the performance of the 12 factor, 36-item Comprehensive Marijuana Motives Questionnaire (CMMQ) among a sample of medical cannabis patients. METHODS: Study participants were adults ages 21years or older with scheduled appointments to obtain new or renewed medical cannabis certification from clinics in one Midwestern state (n=1116)...
August 3, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28820949/association-between-patient-factors-and-outcome-of-synthetic-cartilage-implant-hemiarthroplasty-vs-first-metatarsophalangeal-joint-arthrodesis-in-advanced-hallux-rigidus
#9
Andy Goldberg, Dishan Singh, Mark Glazebrook, Chris M Blundell, Gwyneth De Vries, Ian L D Le, Dominic Nielsen, M Elizabeth Pedersen, Anthony Sakellariou, Matthew Solan, Alastair S E Younger, Timothy R Daniels, Judith F Baumhauer
BACKGROUND: We evaluated data from a clinical trial of first metatarsophalangeal joint (MTPJ1) implant hemiarthroplasty and arthrodesis to determine the association between patient factors and clinical outcomes. METHODS: Patients ≥18 years with hallux rigidus grade 2, 3, or 4 were treated with synthetic cartilage implant MTPJ1 hemiarthroplasty or arthrodesis. Pain visual analog scale (VAS), Foot and Ankle Ability Measure (FAAM) sports and activities of daily living (ADL) scores, and Short Form-36 Physical Function (SF-36 PF) subscore were obtained preoperatively, and at 2, 6, 12, 24, 52, and 104 weeks postoperatively...
August 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28820942/the-effects-of-preheating-and-storage-temperature-on-aroma-profile-and-physical-properties-of-citrus-oil-emulsions
#10
Ying Yang, Chengying Zhao, Guifang Tian, Chang Lu, Shaojie Zhao, Yuming Bao, David Julian McClements, Hang Xiao, Jinkai Zheng
Citrus oils are used as good carrier oil for emulsion fabrication due to their special flavor and various health-promoting functions. In this study, the effects of preheating temperature (30, 40, 50, 60, and 70 oC) and storage temperature (4, 25 and 37 oC) on aroma profiles and physical properties of three citrus-oil (i.e. mandarin, sweet orange and bergamot oils) emulsions were systematically investigated for the first time. The results demonstrated the significant impact of temperature on aroma profile and physical properties...
August 18, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28820909/dose-of-physical-activity-physical-functioning-and-disability-risk-in-mobility-limited-older-adults-results-from-the-life-study-randomized-trial
#11
Roger A Fielding, Jack M Guralnik, Abby C King, Marco Pahor, Mary M McDermott, Catrine Tudor-Locke, Todd M Manini, Nancy W Glynn, Anthony P Marsh, Robert S Axtell, Fang-Chi Hsu, W Jack Rejeski
Understanding the minimal dose of physical activity required to achieve improvement in physical functioning and reductions in disability risk is necessary to inform public health recommendations. To examine the effect of physical activity dose on changes in physical functioning and the onset of major mobility disability in The Lifestyle Interventions and Independence for Elders (LIFE) Study. We conducted a multicenter single masked randomized controlled trial that enrolled participants in 2010 and 2011 and followed them for an average of 2...
2017: PloS One
https://www.readbyqxmd.com/read/28820847/effectiveness-of-a-16-week-high-intensity-cardioresistance-training-program-in-adults
#12
Tina A Greenlee, Daniel R Greene, Nathan J Ward, Ginger E Reeser, Courtney M Allen, Nicholas W Baumgartner, Neal J Cohen, Arthur F Kramer, Charles H Hillman, Aron K Barbey
Greenlee, TA, Greene, DR, Ward, NJ, Reeser, GE, Allen, CM, Baumgartner, NW, Cohen, NJ, Kramer, AF, Hillman, CH, and Barbey, AK. Effectiveness of a 16-week high-intensity cardioresistance training program in adults. J Strength Cond Res 31(9): 2528-2541, 2017-The purpose of this study was to determine the efficacy of a novel, 16-week high-intensity cardioresistance training (HICRT) program on measures of aerobic fitness, agility, aerobic power, muscular endurance, lower-body explosive power, and self-reported activity level...
September 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28820643/a-prototype-ice-melting-probe-for-collecting-biological-samples-from-cryogenic-ice-at-low-pressure
#13
Ashley Davis
In the Solar System, the surface of an icy moon is composed of irregular ice formations at cryogenic temperatures (<200 K), with an oxidized surface layer and a tenuous atmosphere at very low pressure (<10(-6) atm). A lander mission, whose aim is to collect and analyze biological samples from the surface ice, must contain a device that collects samples without refreezing liquid and without sublimation of ice. In addition, if the samples are biological in nature, then precautions must be taken to ensure the samples do not overheat or mix with the oxidized layer...
August 2017: Astrobiology
https://www.readbyqxmd.com/read/28820624/retinopathy-and-optic-atrophy-expanding-the-phenotypic-spectrum-of-pathogenic-variants-in-the-aars2-gene
#14
Jason H Peragallo, Stephanie Keller, Marjo S van der Knaap, Bruno P Soares, Suma P Shankar
BACKGROUND: Optic atrophy may be the sequela of optic nerve injury due to any insult, including isolated and syndromic genetic diseases. Alanyl-tRNA synthetase 2 (AARS2) pathogenic variants have been reported to cause leukodystrophy with ovarian failure, and cardiomyopathy (#615889) as well as combined oxidative phosphorylation deficiency-8 (#614096). We report a young child who presented with decreased vision due to optic atrophy and was found to harbor missense variants in the AARS2 gene expanding the phenotypic expression of the AARS2 gene...
August 18, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28820602/intricate-resonant-raman-response-in-anisotropic-res2
#15
Amber McCreary, Jeffrey R Simpson, Yuanxi Wang, Daniel Rhodes, Kazunori Fujisawa, Luis Balicas, Madan Dubey, Vincent H Crespi, Mauricio Terrones, Angela R Hight Walker
The strong in-plane anisotropy of rhenium disulfide (ReS2) offers an additional physical parameter that can be tuned for advanced applications such as logic circuits, thin-film polarizers, and polarization-sensitive photodetectors. ReS2 also presents advantages for optoelectronics, as it is both a direct-gap semiconductor for few-layer thicknesses (unlike MoS2 or WS2) and stable in air (unlike black phosphorus). Raman spectroscopy is one of the most powerful characterization techniques to non-destructively and sensitively probe the fundamental photo-physics of a 2D material...
August 18, 2017: Nano Letters
https://www.readbyqxmd.com/read/28820516/caregiver-reported-health-outcomes-effects-of-providing-reflexology-for-symptom-management-to-women-with-advanced-breast-cancer
#16
Dawn Frambes, Alla Sikorskii, Irena Tesnjak, Gwen Wyatt, Rebecca Lehto, Barbara Given
PURPOSE/OBJECTIVES: To determine the effects of delivering a reflexology intervention on health outcomes of informal caregivers, and to explore whether intervention effects are moderated by caregiver characteristics. 
. DESIGN: Two-group, randomized clinical trial.
. SETTING: Eight oncology clinics in urban and rural regions of Michigan and Illinois.
. SAMPLE: 180 informal caregivers of patients with advanced breast cancer...
September 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28820271/cam-deformities-and-limited-hip-range-of-motion-are-associated-with-early-osteoarthritic-changes-in-adolescent-athletes-a-prospective-matched-cohort-study
#17
Cody C Wyles, Germán A Norambuena, Benjamin M Howe, Dirk R Larson, Bruce A Levy, Brandon J Yuan, Robert T Trousdale, Rafael J Sierra
BACKGROUND: The natural history of femoroacetabular impingement (FAI) remains incompletely understood. In particular, there is limited documentation of joint damage in adolescent patients with limited range of motion (LROM) of the hip, which is commonly associated with FAI. PURPOSE: To evaluate changes in magnetic resonance imaging (MRI), radiographs, and clinical examinations over 5 years in a group of athletes from a wide variety of sports with asymptomatic LROM of the hip compared with matched controls...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28820047/reversal-of-spinal-cord-ischemia-following-endovascular-thoracic-aortic-aneurysm-repair-with-hyperbaric-oxygen-and-therapeutic-hypothermia
#18
Emmanuel Urquieta, Joseph Varon, Peter H Lin
BACKGROUND: Neurological adverse events with spinal cord ischemia (SCI) remain one of the most feared complications in patients undergoing thoracic endovascular aortic repair (TEVAR). These patients can develop irreversible paraplegia with lifelong consequences with physical and psychological agony. CASE PRESENTATION: We herein present a patient who developed SCI with bilateral lower leg paraplegia on the third postoperative day following TEVAR. Spinal catheter was inserted for spinal fluid drainage...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28819878/aspergillus-bronchitis-in-patients-with-cystic-fibrosis
#19
Claudia Brandt, Jobst Roehmel, Volker Rickerts, Volker Melichar, Nadja Niemann, Carsten Schwarz
Aspergillus fumigatus frequently colonizes the airways of patients with cystic fibrosis (CF) and may cause various severe infections, such as bronchitis. Serological data, sputum dependent markers and longitudinal data of treated cases of Aspergillus bronchitis were evaluated for further description of this infection. This study, which comprises three substudies, aimed to analyze epidemiological data of Aspergillus in CF and the entity of Aspergillus bronchitis. In a first step, data of the German Cystic Fibrosis Registry were used to evaluate the frequency of Aspergillus colonization in patients with CF (n = 2599)...
August 17, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28819746/the-effects-of-resistance-exercise-training-on-anxiety-a-meta-analysis-and-meta-regression-analysis-of-randomized-controlled-trials
#20
REVIEW
Brett R Gordon, Cillian P McDowell, Mark Lyons, Matthew P Herring
BACKGROUND: The salutary effects of resistance exercise training (RET) are well established, including increased strength and function; however, less is known regarding the effects of RET on mental health outcomes. Aerobic exercise has well-documented positive effects on anxiety, but a quantitative synthesis of RET effects on anxiety is needed. OBJECTIVES: To estimate the population effect size for resistance exercise training (RET) effects on anxiety and to determine whether variables of logical, theoretical, and/or prior empirical relation to anxiety moderate the overall effect...
August 17, 2017: Sports Medicine
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