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https://www.readbyqxmd.com/read/29232799/-a-case-of-adult-mature-teratoma-located-in-retroperitoneum
#1
Kimiaki Takagi, Yuka Maekawa, Kenichi Minoshima, Masayoshi Yamaha, Toshio Kato, Shigeaki Yokoi, Masanobu Horie
A 35-year-old man wasreferred to our hospital for treatment of a right adrenal tumor detected by ultrasonography during a physical check-up. Contrast-enhanced abdominal computed tomography revealed a poorly enhanced 74 mm tumor situated adjacent to the upper pole of the right kidney. The tumor consisted of fat with peripheral calcification. Magnetic resonance imaging also revealed a right retroperitoneal tumor with fatty contents and well-circumscribed capsule. The endocrine examination revealed the tumor as non-functioning...
November 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29232671/predicting-trajectories-of-functional-decline-in-60-to-70-year-old-people
#2
Nini H Jonkman, Vieri Del Panta, Trynke Hoekstra, Marco Colpo, Natasja M van Schoor, Stefania Bandinelli, Luca Cattelani, Jorunn L Helbostad, Beatrix Vereijken, Mirjam Pijnappels, Andrea B Maier
BACKGROUND: Early identification of people at risk of functional decline is essential for delivering targeted preventive interventions. OBJECTIVE: The aim of this study is to identify and predict trajectories of functional decline over 9 years in males and females aged 60-70 years. METHODS: We included 403 community-dwelling participants from the InCHIANTI study and 395 from the LASA study aged 60-70 years at baseline, of whom the majority reported no functional decline at baseline (median 0, interquartile range 0-1)...
December 13, 2017: Gerontology
https://www.readbyqxmd.com/read/29232502/do-treatment-patterns-alter-beliefs-cancer-patients-hold-regarding-oral-oncolytic-agents
#3
Alla Sikorskii, Charles W Given, Barbara A Given, Eric Vachon, Victoria Marshall, John C Krauss, Asish Banik, Atreyee Majumder
OBJECTIVE: Cancer patients, particularly those prescribed oral oncolytic medications, face treatment side effects, and temporary and permanent stoppages of treatment. This research examines how events during treatment affect patients' beliefs regarding oral oncolytic medications. METHODS: 272 cancer patients initiating one of 28 oral oncolytic agents were followed for 12 weeks. Assessments of Beliefs About Medications Questionnaire (BMQ), symptoms, physical function, and depression measures were performed during telephone interviews at intake (medication start) and 4, 8, and 12 weeks...
December 12, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/29232316/prime-a-novel-low-mass-high-repetition-approach-to-improve-function-in-older-adults
#4
Jason D Allen, Mitch D VanBruggen, Neil M Johannsen, Jennifer L Robbins, Daniel P Credeur, Carl F Pieper, Richard Sloane, Conrad P Earnest, Timothy S Church, Eric Ravussin, William E Kraus, Michael A Welsch
INTRODUCTION: The ability to maintain functional independence in a rapidly aging population results in an increased life expectancy without corresponding increases in health care costs. The accelerated decline in VO2peak after the age of 65 is primarily due to peripheral tissue changes rather than centrally mediated factors. The purpose of this study was to determine if the PRIME (Peripheral Remodeling through Intermittent Muscular Exercise) approach, consisting of a low mass, high repetition/duration skeletal muscle focused training regimen would provide superior functional benefits in participants above 70 years old and at risk for losing functional independence...
December 11, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29232283/levocarnitine-for-the-treatment-of-valproic-acid-induced-hyperammonemic-encephalopathy-in-children-the-experience-of-large-tertiary-care-pediatric-hospital-and-a-poison-center
#5
Miguel Glatstein, Pedro Bonifacio Rino, Silvina de Pinho, Dennis Scolnik, Dikla Pivko-Levi, Christopher Hoyte
BACKGROUND: Although rare, symptomatic hyperammonemia is sometimes associated with valproic acid (VPA), especially in children. L-carnitine (levocarnitine), sometimes classified as an essential amino acid, is vital to mitochondrial utilization of fatty acids and can be helpful in treating this condition. The data supporting this, however, are limited. STUDY QUESTION: The aim of the study was to illustrate the role of L-carnitine in the treatment of patients with VPA-induced hyperammonemic encephalopathy (VPE) at 2 different institutions...
November 22, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29232263/can-the-critically-ill-patient-generate-sufficient-energy-to-facilitate-exercise-in-the-icu
#6
Danielle E Bear, Selina M Parry, Zudin A Puthucheary
PURPOSE OF REVIEW: Trials of physical rehabilitation post critical illness have yet to deliver improved health-related quality of life in critical illness survivors. Muscle mass and strength are lost rapidly in critical illness and a proportion of patients continue to do so resulting in increased mortality and functional disability. Addressing this issue is therefore fundamental for recovery from critical illness. RECENT FINDINGS: Altered mitochondrial function occurs in the critically ill and is likely to result in decreased adenosine tri-phosphate (ATP) production...
December 9, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/29232259/the-experience-of-head-and-neck-cancer-survivorship-including-laryngectomy-an-integrated-biopsychosocial-model
#7
Marlene C Jacobson
PURPOSE OF REVIEW: The head and neck cancer (HNC) survivorship experience is unique among cancer populations. This review seeks to explore the HNC survivor experience associated with altered upper aerodigestive tract (UADT) function using principles of survivorship. RECENT FINDINGS: HNC survivors experience complex physical, functional, and psychosocial challenges related to UADT dysfunction. Interventions need to address all of these dimensions being mindful of the survivor experience...
December 9, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29232150/unusual-ferroelectricity-in-two-dimensional-perovskite-oxide-thin-films
#8
Jinlian Lu, Wei Luo, Junsheng Feng, Hongjun Xiang
Two-dimensional (2D) ferroelectricity have attracted much attention due to their applications in novel miniaturized devices such as non-volatile memories, field effect transistors and sensors. Since most of the commercial ferroelectric (FE) devices are based on ABO3 perovskite oxides, it is important to investigate the properties of 2D ferroelectricity in perovskite oxides thin films. Here, based on density functional theory (DFT) calculations, we find that there exist three kinds of in-plane ferroelectric states which originate from different microscopic mechanisms: (i) a proper FE state with the polarization along [110] due to the second-order Jahn-Teller effect related to the B ion with empty d-orbitals; (ii) a robust FE state with the polarization along [100] induced by the surface effect; (iii) a hybrid improper FE state with the polarization along [110] that is induced by the tri-linear coupling between two rotational modes and the A-site displacement...
December 12, 2017: Nano Letters
https://www.readbyqxmd.com/read/29231958/medical-issues-in-playing-the-oboe-a-literature-review
#9
REVIEW
Sofia Banzhoff, Maria Del Mar Ropero, Gabriele Menzel, Tatjana Salmen, Manfred Gross, Philipp P Caffier
Playing a musical instrument can affect physical and mental health. A literature review was conducted to determine the prevalence of health problems among oboists, which medical conditions can be caused or exacerbated by playing, whether oboe playing can be a protective factor, and whether recommendations are possible as to who should or should not play the oboe. Searches in 7 databases (Medline, Embase, Cochrane Library, Web of Science, SocIndex, PsyIndex, Psychinfo) yielded a total of 950 studies; after exclusion of duplicates and those not meeting eligibility criteria, 37 articles were selected for final analysis...
December 2017: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/29231868/a-data-driven-response-virtual-sensor-technique-with-partial-vibration-measurements-using-convolutional-neural-network
#10
Shan-Bin Sun, Yuan-Yuan He, Si-Da Zhou, Zhen-Jiang Yue
Measurement of dynamic responses plays an important role in structural health monitoring, damage detection and other fields of research. However, in aerospace engineering, the physical sensors are limited in the operational conditions of spacecraft, due to the severe environment in outer space. This paper proposes a virtual sensor model with partial vibration measurements using a convolutional neural network. The transmissibility function is employed as prior knowledge. A four-layer neural network with two convolutional layers, one fully connected layer, and an output layer is proposed as the predicting model...
December 12, 2017: Sensors
https://www.readbyqxmd.com/read/29231753/rates-of-insufficiency-and-deficiency-of-vitamin-d-levels-in-elite-professional-male-and-female-skiers-a-chronobiologic-approach
#11
Jacopo Antonino Vitale, Giovanni Lombardi, Luca Cavaleri, Rosa Graziani, Herbert Schoenhuber, Antonio La Torre, Giuseppe Banfi
Vitamin D is essential for the maintenance and promotion of musculoskeletal health, for the functioning of the immune, cardiovascular and reproductive systems, and its main action is to keep calcium and phosphate plasmatic physiological concentrations at intestinal, renal and bony level. Vitamin D affects several parameters related to physical performance too and a particularly high percentage of vitamin D insufficiency and deficiency in professional athletes has been observed. Several variables are able to impair the synthesis of 25(OH)D in athletes, specifically both genetic and environmental factors, but the most probable explanation for the deficient/insufficient vitamin D levels is the insufficient ultraviolet B light (UVB) exposure during winter...
December 12, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29231752/differences-between-slovak-and-dutch-patients-scheduled-for-coronary-artery-bypass-graft-surgery-regarding-clinical-and-psychosocial-predictors-of-physical-and-mental-health-related-quality-of-life
#12
Noha El-Baz, Daniela Ondusova, Martin Studencan, Jaroslav Rosenberger, Sijmen A Reijneveld, Jitse P van Dijk, Berrie Middel
BACKGROUND: Differences in health-related quality of life in coronary artery disease patients and associated factors between patients of central and western European descent are rarely investigated. We aim to test differences between Dutch and Slovak health-related quality of life, whether nationality predicted health-related quality of life and if standardised beta weights of health-related quality of life determinants differ across countries. DESIGN: An observational multicentre study at university cardiac centres in the Netherlands and Slovakia...
December 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29231736/preparation-and-membrane-properties-of-oxidized-ceramide-derivatives
#13
Takaaki Matsufuji, Masanao Kinoshita, Anna Möuts, J Peter Slotte, Nobuaki Matsumori
Ceramide is a bioactive lipid with important roles in several biological processes including cell proliferation and apoptosis. Although 3-ketoceramides that contain a keto group in place of the 3-OH group of ceramide occur naturally, ceramide derivatives oxidized at the primary 1-OH group have not been identified to date. In order to evaluate how the oxidative state of the 1-OH group affects the physical properties of membranes, we prepared novel ceramide derivatives in which the 1-OH group was oxidized to a carboxylic acid (PCerCOOH) or methylester (PCerCOOMe), and examined the rigidity of their monolayers and the formation of gel domains in palmitoyloleoylphosphatidylcholine (POPC) or sphingomyelin (SM) bilayers...
December 12, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29231216/aronia-citrus-juice-polyphenol-rich-juice-intake-and-elite-triathlon-training-a-lipidomic-approach-using-representative-oxylipins-in-urine
#14
Libia Alejandra García-Flores, Sonia Medina, Cristina Gómez, Craig E Wheelock, Roberto Cejuela, José Miguel Martínez-Sanz, Camille Oger, Jean-Marie Galano, Thierry Durand, Álvaro Hernández-Sáez, Federico Ferreres, Ángel Gil-Izquierdo
In the present study, we examined whether particular urinary oxylipins (isoprostanes (IsoPs), leukotrienes (LTs), prostaglandins (PGs), and thromboxanes (TXs)) in 16 elite triathletes could alter during 145 days of training. Within this time span, 45 days were dedicated to examining the effects of the intake of a beverage rich in polyphenols (one serving: 200 mL per day) supplemented in their diet. The beverage was a mixture of citrus juice (95%) and Aronia melanocarpa juice (5%) (ACJ). Fifty-two oxylipins were analyzed in the urine...
December 12, 2017: Food & Function
https://www.readbyqxmd.com/read/29231059/association-between-hand-grip-strength-and-erectile-dysfunction-in-older-men
#15
Ho Seok Chung, Min-Ho Shin, Kwangsung Park
OBJECTIVES: To evaluate the association between handgrip strength and erectile dysfunction (ED) in community-dwelling older men. METHODS: This cross-sectional study included 1771 participants of the Dong-gu Study. Handgrip strength was measured with a handheld dynamometer. ED was assessed with the Korean version of the International Index of Erectile Function (IIEF). ED was categorized as none to mild (IIEF-EF scores of 13-30) and moderate to severe (IIEF-EF scores of 0-12)...
December 12, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29230917/interfacial-nanoprecipitation-toward-stable-and-responsive-microbubbles-and-their-use-as-a-resuscitative-fluid
#16
Yifeng Peng, Raymond Seekell, Alexis Cole, Jemima Lamothe, Andrew Lock, Sarah van den Bosch, Xiaoqi Tang, John Kheir, Brian Polizzotti
We report a new approach to prepare stable microbubbles (MBs) via interfacial nanoprecipitation of bioabsorbable polymers at air/liquid interface. This facile method offers robust control over MBs morphology and chemo-physical properties by simple chemical modifications. This approach is amenable to large-scale manufacturing, and is useful to develop functional MBs for advanced biomedical applications. To demonstrate this, we created a MB-based intravenous oxygen carrier that undergoes pH-triggered self-elimination...
December 11, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29230873/non-coded-amino-acids-in-protein-engineering-structure-activity-relationship-studies-of-hirudin-thrombin-interaction
#17
Vincenzo De Filippis, Laura Acquasaliente, Giulia Pontarollo, Daniele Peterle
The advent of recombinant DNA technology allowed to site-specifically insert, delete or mutate almost any amino acid in a given protein, significantly improving our knowledge of protein structure, stability and function. Nevertheless, a quantitative description of the physical and chemical basis that makes a polypeptide chain to efficiently fold into a stable and functionally active conformation is still elusive. This mainly originates from the fact that nature combined, in a yet unknown manner, different properties (i...
December 12, 2017: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/29230843/cardiac-function-in-pediatric-patients-with-congenital-adrenal-hyperplasia-due-to-21-hydroxylase-deficiency
#18
Christiaan F Mooij, Milanthy S Pourier, Gert Weijers, Chris L de Korte, Zina Fejzic, Hedi L Claahsen van der Grinten, Livia Kapusta
BACKGROUND: Hyperandrogenism and exogenous glucocorticoid excess may cause unfavorable changes in the cardiovascular risk profile of patients with congenital adrenal hyperplasia (CAH). OBJECTIVE: To evaluate the cardiac function in pediatric patients with CAH. PATIENTS AND METHODS: 27 pediatric patients with CAH, aged 8-16 years, were evaluated by physical examination, electrocardiogram (ECG), conventional echocardiography, tissue Doppler imaging and two-dimensional (2D) myocardial strain (rate) imaging...
December 11, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29230719/resveratrol-and-or-exercise-training-counteract-aging-associated-decline-of-physical-endurance-in-aged-mice-targeting-mitochondrial-biogenesis-and-function
#19
Marwa Hassan Muhammad, Mona Maher Allam
Mitochondrial dysfunction and decreased mitochondrial content are hallmarks of aging that leads to decreased physical endurance. Our aim was to explore the anti-aging effect of resveratrol (RSVT) supplementation, a polyphenol, and/or exercise training, started at an older age, on improving physical activity, therefore, help in frailty avoidance and promotion of healthy aging in elderly. Eighteen-month-old aged mice received RSVT (15 mg/kg/day) and/or exercise trained for 4 weeks showed significant longer time to exhaustion with decreased blood lactate and free fatty acids levels associated with improved oxidative stress evidenced by decreased gastrocnemius muscle lipid peroxidation and increased antioxidant enzymes activities, catalase and superoxide dismutase, when compared to aged mice control group...
December 11, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29230635/quality-of-life-and-growth-after-childhood-craniopharyngioma-results-of-the-multinational-trial%C3%A2-kraniopharyngeom-2007
#20
Kerstin Heinks, Svenja Boekhoff, Anika Hoffmann, Monika Warmuth-Metz, Maria Eveslage, Junxiang Peng, Gabriele Calaminus, Hermann L Müller
CONTEXT: Quality of life (QoL) after childhood-onset craniopharyngioma (CP) is frequently impaired due to tumor and/or treatment-related factors such as endocrine deficits and hypothalamic involvement/lesions. PATIENTS AND METHODS: In a multinational trial, we prospectively analyzed parental and self-assessment of CP patient QoL at 3 months, 1 and 3 years after CP diagnosis related to growth hormone (GH) substitution. 47 of 194 CP recruited between 2007 and 2015 in KRANIOPHARYNGEOM 2007 were analyzed for QoL 1 and 3 years after CP diagnosis...
December 11, 2017: Endocrine
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