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Functional Movement Screen

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https://www.readbyqxmd.com/read/29665094/newborn-screening-a-disease-changing-intervention-for-glutaric-aciduria-type-1
#1
Nikolas Boy, Katharina Mengler, Eva Thimm, Katharina A Schiergens, Thorsten Marquardt, Natalie Weinhold, Iris Marquardt, Anibh M Das, Peter Freisinger, Sarah C Grünert, Judith Vossbeck, Robert Steinfeld, Matthias R Baumgartner, Skadi Beblo, Andrea Dieckmann, Andrea Näke, Martin Lindner, Jana Heringer, Georg F Hoffmann, Chris Mühlhausen, Esther M Maier, Regina Ensenauer, Sven F Garbade, Stefan Kölker
OBJECTIVE: Untreated individuals with glutaric aciduria type 1 (GA1) commonly present with a complex, predominantly dystonic movement disorder (MD) following acute or insidious onset striatal damage. Implementation of GA1 into newborn screening (NBS) programmes has improved the short-term outcome. It remains unclear, however, whether NBS changes the long-term outcome and which variables are predictive. METHODS: This prospective, observational, multi-centre study includes 87 patients identified by NBS, four patients missed by NBS and three women with GA1 identified by positive NBS results of their unaffected children...
April 17, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29664647/amphiphobic-septa-enhance-the-mechanical-stability-of-free-standing-bilayer-lipid-membranes
#2
Daichi Yamaura, Daisuke Tadaki, Shun Araki, Miyu Yoshida, Kohei Arata, Takeshi Ohori, Ken-Ichi Ishibashi, Miki Kato, Teng Ma, Ryusuke Miyata, Hideaki Yamamoto, Ryugo Tero, Masao Sakuraba, Toshio Ogino, Michio Niwano, Ayumi Hirano-Iwata
Artificial bilayer lipid membranes (BLMs) provide well-defined systems for investigating the fundamental properties of membrane proteins, including ion channels, and in screening the effect of drugs that act on them. However, the application of this technique is limited due to the low stability and low reconstitution efficiency of the process. We previously reported on improving the stability of BLM based on the fabrication of microapertures having a tapered edge in SiO2/Si3N4 septa and efficient ion channel incorporation based on vesicle fusion accelerated by a centrifugal force...
April 17, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29661612/hearing-self-motion-perception-mobility-and-aging
#3
REVIEW
Jennifer Campos, Robert Ramkhalawansingh, M Kathleen Pichora-Fuller
Hearing helps us know where we are relative to important events and objects in our environment and it allows us to track our changing position dynamically over space and time. Auditory cues are used in combination with other sensory inputs (visual, vestibular, proprioceptive) to help us perceive our own movements through space, known as self-motion perception. Whether we are maintaining standing balance, walking, or driving, audition can provide unique and important information to help optimize self-motion perception, and consequently to support safe mobility...
March 31, 2018: Hearing Research
https://www.readbyqxmd.com/read/29623750/considerations-in-the-diagnosis-and-accelerated-return-to-sport-of-a-professional-basketball-player-with-a-triceps-surae-injury-a-case-report
#4
Philip A Anloague, Donald S Strack
Study Design Case report. Background Acute injuries of the triceps surae and Achilles tendon are common in sports. Rupture of the plantaris tendon can be challenging to diagnose. There is limited evidence detailing the diagnosis, rehabilitation, and accelerated return to sport of elite professional basketball players who have suffered calf injuries. Case Description A 25-year-old male professional basketball player sustained injury to his calf during a professional basketball game. This case report details the presumptive diagnosis, graduated progression of intervention, and return to play of a professional sports person with a likely isolated plantaris tendon tear...
April 6, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29606084/towards-novel-inhibitors-against-kdsb-a-highly-specific-and-selective-broad-spectrum-bacterial-enzyme
#5
Sajjad Ahmad, Saad Raza, Asma Abro, Klaus R Liedl, Syed Sikander Azam
KdsB (3-deoxy-manno-octulosonate cytidylyltransferase) is a highly specific and selective bacterial enzyme that catalyzes KDO (3-Deoxy-D-mano-oct-2-ulosonic acid) activation in KDO biosynthesis pathway. Failure in KDO biosynthesis causes accumulation of lipid A in the bacterial outer membrane that leads to cell growth arrest. This study reports a combinatorial approach comprising virtual screening of natural drugs library, molecular docking, computational pharmacokinetics, molecular dynamics simulation, and binding free energy calculations for the identification of potent lead compounds against the said enzyme...
March 31, 2018: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/29599859/functional-movements-in-japanese-mini-basketball-players
#6
Kenji Kuzuhara, Masashi Shibata, Junta Iguchi, Ryo Uchida
Functional movement screen (FMS) has been used to establish normative data and determine potential injury risk for young adults and athletes, but there are few data in elementary school-age children. The purpose of this study was to establish fundamental values for the FMS in elementary school-age mini-basketball players. Secondary purposes were to examine relationships between functional movement patterns and age, peak height velocity (PHV), and body mass index (BMI), and to compare functional movement patterns between boys and girls and between individuals with and without a history of injury...
March 2018: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29576925/effects-of-ulnar-styloid-fractures-on-unstable-distal-radius-fracture-outcomes-a-systematic-review-of-comparative-studies
#7
Sami Almedghio, Mohammed Shoaib Arshad, Fayez Almari, Indranil Chakrabarti
Purpose  In this literature review, functional outcomes such as Disability of Arm, Shoulder and Hand (DASH) score and the visual analog scale (VAS) of pain along with clinical outcomes such as range of movement and grip strength of treated distal radius fractures (DRF) accompanied with ulnar styloid fractures (USF) will be compared with those with isolated DRF. Materials and Methods  We analyzed articles from MEDLINE, Embase, and CINAHL that met our predetermined inclusion and exclusion criteria as per the Preferred Reporting Items for Systematic Reviews and Meta-analysis statements...
April 2018: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/29559417/wrist-position-sense-acuity-and-its-relation-to-motor-dysfunction-in-children-with-developmental-coordination-disorder
#8
Yu-Ting Tseng, Chia-Liang Tsai, Fu-Chen Chen, Jürgen Konczak
This study obtained objective measures of wrist position sense to verify that children with DCD have proprioceptive deficits. In addition, it examined the relationship of wrist proprioceptive impairment with fine motor and balance function. Twenty children with DCD and thirty typically developing children (TD) aged 10-11 years old were recruited and screened using the Movement Assessment Battery for Children (MABC-2). The DCD group had total MABC-2 score below 5th percentile, and TD group was above 25th percentile...
March 17, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29557385/proteomic-analysis-of-trans-hemispheric-motor-cortex-reorganization-following-contralateral-c-7-nerve-transfer
#9
Yin Yuan, Xiu-Yue Xu, Jie Lao, Xin Zhao
Nerve transfer is the most common treatment for total brachial plexus avulsion injury. After nerve transfer, the movement of the injured limb may be activated by certain movements of the healthy limb at the early stage of recovery, i.e., trans-hemispheric reorganization. Previous studies have focused on functional magnetic resonance imaging and changes in brain-derived neurotrophic factor and growth associated protein 43, but there have been no proteomics studies. In this study, we designed a rat model of total brachial plexus avulsion injury involving contralateral C7 nerve transfer...
February 2018: Neural Regeneration Research
https://www.readbyqxmd.com/read/29548620/-epidemiology-and-diagnosis-strategy-cngof-has-endometriosis-guidelines
#10
A Fauconnier, B Borghese, C Huchon, I Thomassin-Naggara, C-A Philip, T Gauthier, N Bourdel, A Denouel, A Torre, P Collinet, M Canis, X Fritel
Based on the best evidence available, we have provided guidelines for clinical practice to target the nature of endometriosis as a disease, the consequences of its natural history on management, and the clinical and imaging evaluation of the disease according to the level of care (primary care, specialized or referral). The frequency of endometriosis is unknown in the general population; endometriosis requires management when it causes symptoms (pain, infertility) or when it affect the function of an organ...
March 13, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29543126/effect-of-a-suspension-trainer-based-movement-program-on-measures-of-fitness-and-functional-movement-in-children-a-pilot-study
#11
Christine W St Laurent, Brittany Masteller, John Sirard
PURPOSE: The purpose of this pilot study was to assess the efficacy of a suspension-training movement program to improve muscular- and skill-related fitness and functional movement in children, compared with controls. METHODS: In total, 28 children [male: 46%; age: 9.3 (1.5) y; body mass index percentile: 68.6 (27.5)] were randomly assigned to intervention (n = 17) or control (n = 11) groups. The intervention group participated in a 6-week suspension-training movement program for two 1-hour sessions per week...
March 15, 2018: Pediatric Exercise Science
https://www.readbyqxmd.com/read/29543122/the-influence-of-circadian-variation-on-aetiological-markers-of-ankle-injury
#12
Chris Brogden, Kelly Marrin, Richard Page, Matt Greig
CONTEXT: Clinical and functional assessments are performed regularly in sporting environments to screen for performance deficits and injury risk. Circadian rhythms have been demonstrated to affect human performance, however the influence of time of day on a battery of multiple ankle injury risk factors has yet to be established within athletic populations. OBJECTIVES: To investigate the influence of circadian variation on a battery of tests, used to screen for ankle aetiological risk factors...
March 15, 2018: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29526002/migration-of-q-cells-in-caenorhabditis-elegans
#13
Yongping Chai, Zhiwen Zhu, Guangshuo Ou
During C. elegans larval development, the Q neuroblasts produce their lineage by three rounds of divisions along with continuous cell migrations. Their neuronal progeny is dispersed from the pharynx to the anus. This in vivo system to study cell migration is appealing for several reasons. The lineage development is stereotyped; functional analysis and genomic screens are rendered easy and powerful thanks to powerful tools; transgenic manipulations and genome engineering are efficient and can be conveniently combined with live-cell imaging...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29522075/characterization-of-the-relationships-between-sleep-duration-quality-architecture-and-chemosensory-function-in-non-obese-females
#14
Edward J Szczygiel, Sungeun Cho, Robin M Tucker
Little is known about the relationship between sleep and chemosensation. The purpose of this study was to characterize the relationship between chemosensory function and sleep duration, quality and architecture. A total of 56 non-obese (BMI<30 kg/m2) female participants who denied having diagnosed sleep disorders completed testing. Sleep was measured for two nights using a single-channel (A1-A2) electroencephalogram-(EEG) (Zmachine). Sweet taste threshold and preference as well as olfactory threshold, recognition ability, and pleasantness ratings were evaluated...
March 7, 2018: Chemical Senses
https://www.readbyqxmd.com/read/29518691/the-functional-movement-screen-and-modified-star-excursion-balance-test-as-predictors-of-t-test-agility-performance-in-university-rugby-union-and-netball-players
#15
Ross Armstrong, Matt Greig
OBJECTIVES: Agility is a functional requirement of many sports, challenging stability, and commonly cited as a mechanism of injury. The Functional Movement Screen (FMS) and modified Star Excursion Balance Test (mSEBT) have equivocally been associated with agility performance. The aim of the current study was to establish a hierarchical ordering of FMS and mSEBT elements in predicting T-test agility performance. DESIGN: Cross-sectional study design. SETTING: University...
January 17, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29517185/motion-detection-supported-exercise-therapy-in-musculoskeletal-disorders-a-systematic-review
#16
Jonas Verbrugghe, Els Knippenberg, Steven Palmaers, Thomas Matheve, Wout Smeets, Peter Feys, Annemie Spooren, Annick Timmermans
INTRODUCTION: Musculoskeletal disorders (MSDs) are a burden on the healthcare system. Exercise therapy is an important part of MSD rehabilitation. Motion detection systems are developed to support exercise therapy settings. This systematic review aims 1) to investigate which types of motion detection systems have been used as a technological support for exercise therapy, 2) to investigate the characteristics of motion detection supported exercise therapy in relation to its clinical indications, and 3) to evaluate the effectiveness of motion detection supported exercise therapy, in MSD rehabilitation...
March 7, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29510787/kinematic-and-kinetic-analysis-of-repeated-and-static-elev%C3%A3-in-adolescent-female-dance-students
#17
Amit Abraham, Ayelet Dunsky, Madeleine E Hackney, Ruth Dickstein
Elevé is a fundamental dance movement practiced routinely by dance students and serving as an integral component of screening in dance. It consists of ankle plantar flexion (PF) movement and is considered to be a frequent cause of foot and ankle injuries among dancers, with adolescent female dance students being at greatest risk for such injuries. Therefore, gaining additional knowledge regarding elevé functional range of motion (ROM) and inter-leg weightbearing distribution (WBD) properties among adolescent dance students is warranted for pedagogic, screening, injury prevention, and rehabilitation purposes...
March 15, 2018: Journal of Dance Medicine & Science
https://www.readbyqxmd.com/read/29489965/a-new-motor-screening-assessment-for-children-at-risk-for-motor-disorders-construct-validity
#18
Paola Matiko Martins Okuda, Melissa Pangelinan, Carlo Chiorri, Simone Aparecida Capellini, Hugo Cogo-Moreira
OBJECTIVE: To develop a motor screening assessment and provide preliminary evidence of its psychometric properties. METHODS: A sample of 365 elementary school students was assessed, with structural equation modeling applied to obtain evidence of the adequacy of the factor structure of the motor screening assessment. As well, differential item functioning was used to evaluate whether various identifiable subgroups of children (i.e., sex and grade) perform particular tasks differently...
February 2018: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29488319/identification-of-transcripts-potentially-involved-in-neural-tube-closure-using-rna-sequencing
#19
Lexy M Kindt, Alicia R Coughlin, Tianna R Perosino, Haley Ersfeld, Marshall Hampton, Jennifer O Liang
Anencephaly is a fatal human neural tube defect (NTD) in which the anterior neural tube remains open. Zebrafish embryos with reduced Nodal signaling display an open anterior neural tube phenotype that is analogous to anencephaly. Previous work from our laboratory suggests that Nodal signaling acts through induction of the head mesendoderm and mesoderm. Head mesendoderm/mesoderm then, through an unknown mechanism, promotes formation of the polarized epithelium which is capable of undergoing the movements required for closure...
February 27, 2018: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/29485920/age-related-differences-in-functional-hamstring-quadriceps-ratio-following-soccer-exercise-in-female-youth-players-an-injury-risk-factor
#20
Mark De Ste Croix, Abigail Priestley, Rhodri Lloyd, Jon Oliver
PURPOSE: Fatigue negatively alters dynamic knee control, and the functional hamstring/quadriceps ratio (H/QFUNC ) plays an important role in stabilizing the joint. The aim of this study was to investigate the influence of soccer-specific exercise on H/QFUNC in under (U) 13-, U15-, and U17-year-old female soccer players. METHODS: A total of 36 female players performed concentric and eccentric actions of the hamstrings at 60°, 120°, and 180°/s before and after an age group-specific field-based soccer protocol...
February 27, 2018: Pediatric Exercise Science
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