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Functional fitness

Pamela L Geller, Christopher M Stojanowksi
OBJECTIVES: This article uses craniometric allocation as a platform for discussing the legacy of Samuel G. Morton's collection of crania, the process of racialization, and the value of contextualized biohistoric research perspectives in biological anthropology. MATERIALS AND METHODS: Standard craniometric measurements were recorded for seven Seminoles in the Samuel G. Morton Crania Collection and 10 European soldiers from the Fort St. Marks Military Cemetery; all individuals were men and died in Florida during the 19th century...
October 18, 2016: American Journal of Physical Anthropology
Anees A Ansari, Abdul K Parchur, Brijesh Kumar, S B Rai
The design of nanostructured materials with highly stable water-dispersion and luminescence efficiency is an important concern in nanotechnology and nanomedicine. In this paper, we described the synthesis and distinct surface modification on the morphological structure and optical (optical absorption, band gap energy, excitation, emission, decay time, etc.) properties of highly crystalline water-dispersible CaF2:Ce/Tb nanocrystals (core-nanocrystals). The epitaxial growth of inert CaF2 and silica shell, respectively, on their surface forming as CaF2:Ce/Tb@CaF2 (core/shell) and CaF2:Ce/Tb@CaF2@SiO2 (core/shell/SiO2) nanoarchitecture...
December 2016: Journal of Materials Science. Materials in Medicine
Skye P Barbic, Stefan J Cano
This commentary argues the importance of robust, meaningful assessment of clinical and functional outcomes in psychiatry. Outcome assessments should be fit for the purpose of measuring relevant concepts of interest in specific clinical settings. As well, the measurement model selected to develop and test assessments can be critical for guiding care. Three types of measurement models are presented: classical test theory, item response theory, and Rasch measurement theory. To optimise current diagnostic and treatment practices in psychiatry, careful consideration of these models is warranted...
October 2016: BJPsych Bulletin
Enrico Bellato, Roberto Rotini, Alessandro Marinelli, Enrico Guerra, Shawn W O'Driscoll
BACKGROUND: Chronic coronoid deficiency can occur subsequent to coronoid fracture malunion/nonunion or to coronoid hypoplasia or dysplasia resulting from injury during development. Several surgical options have been described to treat this difficult condition, but results are equivocal. We hypothesized that a modified coronoid reconstruction using a radial head osteochondral graft could restore elbow stability and congruity and that a technique involving rigid internal fixation would promote graft union...
October 14, 2016: Journal of Shoulder and Elbow Surgery
William C Scott, Christopher K Giardina, Andrew K Pappa, Tatyana E Fontenot, Meredith L Anderson, Margaret T Dillon, Kevin D Brown, Harold C Pillsbury, Oliver F Adunka, Craig A Buchman, Douglas C Fitzpatrick
HYPOTHESIS: The compound action potential (CAP) is a purely neural component of the cochlea's response to sound, and may provide information regarding the existing neural substrate in cochlear implant (CI) subjects that can help account for variance in speech perception outcomes. BACKGROUND: Measurement of the "total response" (TR), or sum of the magnitudes of spectral components in the ongoing responses to tone bursts across frequencies, has been shown to account for 40 to 50% of variance in speech perception outcomes...
October 4, 2016: Otology & Neurotology
Koenraad S Rhebergen, Thijs H Maalderink, Wouter A Dreschler
OBJECTIVES: The effects of nonlinear signal processing on speech intelligibility in noise are difficult to evaluate. Often, the effects are examined by comparing speech intelligibility scores with and without processing measured at fixed signal to noise ratios (SNRs) or by comparing the adaptive measured speech reception thresholds corresponding to 50% intelligibility (SRT50) with and without processing. These outcome measures might not be optimal. Measuring at fixed SNRs can be affected by ceiling or floor effects, because the range of relevant SNRs is not know in advance...
October 4, 2016: Ear and Hearing
Rachel L Z Goh, Eva Fenwick, Simon E Skalicky
PURPOSE: As health budgets tighten globally, evaluating the cost-effectiveness of glaucoma services is vital; however, there is a lack of validated instruments that measure utility specific to glaucoma patients. We thus evaluated the validity of the Visual Function Questionnaire-Utility Index (VFQ-UI) as a measure of vision-related function and preference-based status in glaucoma. PATIENTS AND METHODS: Cross-sectional study of 141 volunteer patients over 40 years of age with moderate (n=64) or severe (n=36) glaucoma, and 41 controls...
October 2016: Journal of Glaucoma
Aurélia Bugaiska, Alain Méot, Patrick Bonin
: Background/Study Context: It has been found that young adults remember animates better than inanimates. According to the adaptive view of human memory, this is due to the fact that animates are more important for fitness purposes than inanimates. This effect has been ascribed to episodic memory, where older people exhibit difficulties. METHODS: Here the authors investigated whether the animacy effect in memory also occurs for healthy older adults. Older and young adults categorized words for their animacy characteristics and were then given an unexpected recognition test on the words using the Remember/Know paradigm...
October 2016: Experimental Aging Research
Shouwen Zhang, Jie Wang, Jin Pan
CONTEXT: Baicalin has many pharmacological activities, including protective function against myocardial ischemia by antioxidant effects and free radical scavenging activity. However, its rapid elimination half-life in plasma and poor water solubility limits its clinical efficacy. OBJECTIVE: Novel baicalin-loaded PEGylated nanostructured lipid carriers (BN-PEG-NLC) were developed to improve bioavailability of BN, to prolong retention time in vivo and to enhance its protective effect...
October 17, 2016: Drug Delivery
Maudrene Ls Tan, Eric Yh Khoo, Konstadina Griva, Yung Seng Lee, Mohamed Amir, Yasmin Lm Zuniga, Jeannette Lee, E Shyong Tai, Hwee Lin Wee
INTRODUCTION: The Diabetes Health Profile-18 (DHP-18) measures diabetes-related psychological well-being in patients with type 2 diabetes mellitus (T2DM). It includes 3 subscales: psychological distress (PD), barriers to activity and disinhibited eating. The psychometric properties of the DHP have not been evaluated in Asia. The aim of this study was to determine the psychometric properties of the DHP in multiethnic Singapore. MATERIALS AND METHODS: Patients between the ages of 18 to 65 diagnosed with diabetes (either type 1 or type 2) for at least 1 year were recruited from a diabetes outpatient clinic in a tertiary hospital...
September 2016: Annals of the Academy of Medicine, Singapore
Michelle M Martel, Pedro M Pan, Maurício S Hoffmann, Ary Gadelha, Maria C do Rosário, Jair J Mari, Gisele G Manfro, Eurípedes C Miguel, Tomás Paus, Rodrigo A Bressan, Luis A Rohde, Giovanni A Salum
High rates of comorbidities and poor validity of disorder diagnostic criteria for mental disorders hamper advances in mental health research. Recent work has suggested the utility of continuous cross-cutting dimensions, including general psychopathology and specific factors of externalizing and internalizing (e.g., distress and fear) syndromes. The current study evaluated the reliability of competing structural models of psychopathology and examined external validity of the best fitting model on the basis of family risk and child global executive function (EF)...
October 17, 2016: Journal of Abnormal Psychology
Bishnu Thapa, H Bernhard Schlegel
A practical method for calculating the pKa's of selenols in aqueous solution has been developed using density functional theory with the SMD solvation model and up to three explicit water molecules. The pKa's of 30 different organoselenols, 16 with known experimental pKa's, have been calculated using three different functionals (wB97XD, B3LYP, and M06-2X) and two basis sets (6-31+G(d,p) and 6-311++G(d,p)). Calculations using wB97XD and B3LYP with SMD solvation without explicit waters are found have errors of 3-6 pKa units; the errors with M06-2X are somewhat smaller...
October 17, 2016: Journal of Physical Chemistry. A
Arpan Kundu, GiovanniMaria Piccini, Kaido Sillar, Joachim Sauer
For CO and N2 on Mg(2+) sites of the metal-organic framework CPO-27-Mg (Mg-MOF-74), ab initio calculations of Gibbs free energies of adsorption have been performed. Combined with the Bragg-Williams/Langmuir model and taking into account the experimental site availability (76.5%), we obtained adsorption isotherms in close agreement with those in experiment. The remaining deviations in the Gibbs free energy (about 1 kJ/mol) are significantly smaller than the "chemical accuracy" limit of about 4 kJ/mol. The presented approach uses (i) a DFT dispersion method (PBE+D2) to optimize the structure and to calculate anharmonic frequencies for vibrational partition functions and (ii) a "hybrid MP2:(PBE+D2)+ΔCCSD(T)" method to determine electronic energies...
October 17, 2016: Journal of the American Chemical Society
Bas van Bochove, Gerjon Hannink, Pieter Buma, Dirk W Grijpma
Three-armed poly(trimethylene carbonate) macromers with a relatively high molecular weight of 28.9 kg mol(-1) are prepared by ring opening polymerization and subsequent functionalization with methacrylate end groups. A resin suitable for processing by stereolithography is developed using propylene carbonate as a diluent, a photoinitiator, and a dye to control the curing characteristics. The difficulties in building designed structures with digital light processing stereolithography and the ways of optimizing the resin compositions are described in detail...
October 17, 2016: Macromolecular Bioscience
Ugo Corrà
Cardiopulmonary exercise testing (CPET) is a specialized subtype of exercise testing that provides a more accurate and objective measure of cardiorespiratory fitness (CRF). CPET relies on measurement of ventilatory gases during exercise, i.e., a non-invasive procedure that involves the acquisition of expired ventilation and concentrations of oxygen (O2) and carbon dioxide (CO2) during progressive exercise. The non-invasive measurement of ventilation and expired gases permits the most accurate and reproducible quantification of CRF, a grading of the etiology and severity of impairment, and an objective assessment of the response to an intervention...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
E D'Elia, P Ferrero, C Vittori, A Calabrese, V Duino, S Perlini, M Senni
Athletes may have electrocardiogram (ECG) repolarization abnormalities during stress test suggestive for ischemia in the absence of ischemic coronary artery disease, often in a setting of myocardial septum hypertrophy. Global longitudinal strain (GLS) might be altered in these athletes compared to hypertensive patients with the same degree of septal thickness. About 735 consecutive athletes were screened for mandatory assessment of fitness to participate in competitive sports. At the stress test, 23 (19 M, 4 F) were found to have ECG repolarization abnormalities suggestive for ischemia in the presence of normal coronary vessels...
October 17, 2016: Scandinavian Journal of Medicine & Science in Sports
E Sebastião, E A Hubbard, R E Klaren, L A Pilutti, R W Motl
This study compared physical fitness components between fatigued and non-fatigued persons with MS and examined those components as correlates of fatigue. Sixty-two ambulatory persons with MS completed the Modified Fatigue Impact Scale (MFIS) and underwent assessments of cardiorespiratory capacity, lower extremity muscle strength (i.e., peak torque and asymmetry), body composition, and static balance over two different sessions 7 days apart. Participants were allocated into fatigue groups based on MFIS scores (non-fatigued group (i...
October 17, 2016: Scandinavian Journal of Medicine & Science in Sports
Mikhail Trifonov
The first-order temporal structure functions (SFs), i.e., the first-order statistical moment of absolute increments of scaled multichannel resting state EEG signals in healthy children and teenagers over a wide range of temporal separation (time lags) are computed. Our research shows that the sill level (asymptote) of the SF is mainly defined by a determinant of EEG correlation matrix reflecting the EEG spatial structure. The temporal structure of EEG is found to be characterized by power-law scaling or statistical-scale invariance over time scales less than 0...
February 25, 2016: Brain Informatics
Julius T Kamwesiga, Lena von Koch, Anders Kottorp, Susanne Guidetti
BACKGROUND: Knowledge is scarce about the impact of stroke in Uganda, and culturally adapted, psychometrically tested patient-reported outcome measures are lacking. The Stroke Impact Scale 3.0 is recommended, but it has not been culturally adapted and validated in Uganda. OBJECTIVE: To culturally adapt and determine the psychometric properties of the Stroke Impact Scale 3.0 in the Ugandan context on a small scale. METHOD: The Stroke Impact Scale 3...
2016: SAGE Open Medicine
Jai Thilak, Melvin J George
BACKGROUND: The correct sizing of the components in both anteroposterior and mediolateral (ML) dimensions is crucial for the success of a total knee arthroplasty (TKA). The size of the implants selected is based on the intraoperative measurements. The currently used TKA implants available to us are based on morphometric measurements obtained from a Western/Caucasian population. Hence, the risk of component ML mismatch is more common in Asian sub-population, as they are of a smaller built and stature...
September 2016: Indian Journal of Orthopaedics
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