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https://www.readbyqxmd.com/read/29775766/miyazaki-syndrome-due-to-ventriculoperitoneal-shunt-treatment-a-case-report
#1
Anita Kovács, Tamás Németh, Angéla Csomor, Tímea Novák, Ferenc Kövér, Erika Vörös
The signs and pathomechanism of Miyazaki syndrome is presented through the case of a young female patient. The patient underwent placement of a ventriculoperitoneal (VP) shunt with a pressure-adjustable valve for communicating hydrocephalus years before presenting to our department with the complaints of constant headache and unsteady gait. On the basis of the clinical picture and her history, plain and contrast-enhanced cranial and whole spine magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) examinations were performed, with the scans revealing signs indicative of cerebrospinal fluid (CSF) hypotension typical of Miyazaki syndrome...
May 15, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29770299/regenerative-medicine-therapy-for-single-ventricle-congenital-heart-disease
#2
REVIEW
Chetan Ambastha, Gregory J Bittle, David Morales, Nathaniel Parchment, Progyaparamita Saha, Rachana Mishra, Sudhish Sharma, Alexander Vasilenko, Muthukumar Gunasekaran, Manal T Al-Suqi, Deqiang Li, Peixin Yang, Sunjay Kaushal
One of the most complex forms of congenital heart disease (CHD) involving single ventricle physiology is hypoplastic left heart syndrome (HLHS), characterized by underdevelopment of the left ventricle (LV), mitral and aortic valves, and narrowing of the ascending aorta. The underdeveloped LV is incapable of providing long-term systemic flow, and if left untreated, the condition is fatal. Current treatment for this condition consists of three consecutive staged palliative operations: the first is conducted within the first few weeks of birth, the second between 4 to 6 months, and the third and final surgery within the first 4 years...
April 2018: Translational Pediatrics
https://www.readbyqxmd.com/read/29757467/severe-tricuspid-regurgitation-due-to-interactions-with-right-ventricular-permanent-pacemaker-or-defibrillator-leads
#3
REVIEW
Cory R Trankle, Zachary M Gertz, Jayanthi N Koneru, Vigneshwar Kasirajan, Patricia Nicolato, Hem Bhardwaj, Kenneth A Ellenbogen, Gautham Kalahasty
Although thought to be a rare event, permanent pacemakers and implantable cardioverter-defibrillators with right ventricular intracardiac leads have the potential to induce tricuspid valve dysfunction. Adverse lead-valve interactions can take place through a variety of mechanisms including damage at the time of implantation, leaflet pinning, or long-term fibrosis encapsulating the leaflet tissue. Clinical manifestations can display a wide range of severity, as well as a highly variable time span between implantation and hemodynamic deterioration...
May 14, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29755074/-structural-deterioration-of-a-bovine-pericardial-valve-in-a-tricuspid-position-14-years-postoperatively-report-of-a-case
#4
Kazunori Ota, Koyu Tanaka, Naoki Asano, Shigeyoshi Gon, Masahito Saito, Kazuho Niimi, Hiromichi Inoue, Motohiko Tamura, Yuji Matsumura, Toshihiro Ohata, Hirotsugu Fukuda, Hiroshi Takano
Although nonstructural dysfunction of a bioprosthesis caused by pannus formation or native valve attachment has been well described, structural valve deterioration( SVD) caused by calcification or tear of a bioprosthesis, especially a bovine pericardial valve, is very rare in the tricuspid position. We report a case of redo tricuspid valve surgery for SVD 14 years after tricuspid valve replacement( TVR) using a Carpentier-Edwards Perimount (CEP) pericardial valve. A 71-year-old woman was referred to our hospital because of exertional dyspnea and pre-syncope...
March 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29713021/risk-of-cardiomyopathy-and-cardiac-arrhythmias-in-patients-with-nonalcoholic-fatty-liver-disease
#5
REVIEW
Quentin M Anstee, Alessandro Mantovani, Herbert Tilg, Giovanni Targher
Nonalcoholic fatty liver disease (NAFLD) is a common, progressive liver disease that affects up to one-quarter of the adult population worldwide. The clinical and economic burden of NAFLD is mainly due to liver-related morbidity and mortality (nonalcoholic steatohepatitis, cirrhosis or hepatocellular carcinoma) and an increased risk of developing fatal and nonfatal cardiovascular disease, chronic kidney disease and certain types of extrahepatic cancers (for example, colorectal cancer and breast cancer). Additionally, there is now accumulating evidence that NAFLD adversely affects not only the coronary arteries (promoting accelerated coronary atherosclerosis) but also all other anatomical structures of the heart, conferring an increased risk of cardiomyopathy (mainly left ventricular diastolic dysfunction and hypertrophy, leading to the development of congestive heart failure), cardiac valvular calcification (mainly aortic-valve sclerosis), cardiac arrhythmias (mainly atrial fibrillation) and some cardiac conduction defects...
April 30, 2018: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29701398/trauma-an-unusual-cause-of-endocarditis
#6
Ana Braga, Marta Marques, Miguel Abecacis, José Pedro Neves
INTRODUCTION: Infective endocarditis (IE) remains a dangerous condition with considerable associated mortality. Usual risk factors for IE include the presence of a prosthetic heart valve, structural or congenital heart disease, intravenous drug use, and a recent history of invasive procedures. METHODS: The authors describe the case report of a patient with IE having trauma as an unusual risk factor. RESULTS: A 33-year old male patient was referred to our department due to infective endocarditis...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29671812/enlightening-the-association-between-bicuspid-aortic-valve-and-aortopathy
#7
REVIEW
Froso Sophocleous, Elena Giulia Milano, Giulia Pontecorboli, Pierpaolo Chivasso, Massimo Caputo, Cha Rajakaruna, Chiara Bucciarelli-Ducci, Costanza Emanueli, Giovanni Biglino
Bicuspid aortic valve (BAV) patients have an increased incidence of developing aortic dilation. Despite its importance, the pathogenesis of aortopathy in BAV is still largely undetermined. Nowadays, intense focus falls both on BAV morphology and progression of valvular dysfunction and on the development of aortic dilation. However, less is known about the relationship between aortic valve morphology and aortic dilation. A better understanding of the molecular pathways involved in the homeostasis of the aortic wall, including the extracellular matrix, the plasticity of the vascular smooth cells, TGFβ signaling, and epigenetic dysregulation, is key to enlighten the mechanisms underpinning BAV-aortopathy development and progression...
April 19, 2018: Journal of Cardiovascular Development and Disease
https://www.readbyqxmd.com/read/29642696/periprocedural-and-perioperatory-management-of-patients-with-tricuspid-valve-disease
#8
Fabrizio Monaco, Ambra L DI Prima, Monica DE Luca, Gaia Barucco, Alberto Zangrillo
Tricuspid regurgitation (TR) is a common valvular lesion which may affect morbidity and mortality. It can be related to an intrinsic abnormality of the tricuspid valve leaflets (organic) or secondary to annular dilatation (functional). Often organic and functional TR coexist in the same patient. A long standing TR is associated with ascites, congestive hepatopathy, peripheral edema, renal failure, and abdominal fullness which significantly affect the outcome. In particular, the perioperative course may be complicated due to both the presence of comorbidities and the development of a severe postoperative right ventricle (RV) dysfunction...
April 11, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29626079/acute-versus-chronic-ischemic-mitral-regurgitation-an-echocardiographic-study-of-anatomy-and-physiology
#9
Shun Nishino, Nozomi Watanabe, Toshiyuki Kimura, Nehiro Kuriyama, Yoshisato Shibata
BACKGROUND: Little is known on the mechanism of acute ischemic mitral regurgitation (IMR) caused by sudden-onset left ventricular dysfunction in acute myocardial infarction (MI). We sought to investigate the mitral valve (MV) complex geometry in acute IMR in comparison with chronic IMR by 2-dimensional and 3-dimensional transthoracic echocardiography. METHODS AND RESULTS: Forty-four first-onset acute MI and 36 previous MI with ≥moderate IMR were examined by 2-dimensional/3-dimensional transthoracic echocardiography...
April 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29608496/antithrombotic-management-of-patients-with-prosthetic-heart-valves
#10
Abdallah Sanaani, Srikanth Yandrapalli, Joseph Michael Harburger
Valvular heart disease is a major public health issue. The prevalence of valvular heart disease is expected to increase due to an aging population. Valve dysfunction manifests as valve stenosis, regurgitation, or both, due to various etiologies. Valve repair and replacement are the main treatment options for severe valve dysfunction. Valve replacement is achieved by using either a mechanical or a bioprosthetic valve. Mechanical valves are more durable but require lifelong anticoagulation with associated complications...
March 30, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29608495/medical-management-of-rheumatic-heart-disease-a-systematic-review-of-the-evidence
#11
E Anne Russell, Warren F Walsh, Ben Costello, Alex Ja McLellan, Alex Brown, Christopher M Reid, Lavinia Tran, Graeme P Maguire
Rheumatic heart disease (RHD) is an important cause of heart disease globally. Its management can encompass medical and procedural (catheter and surgical) interventions. Literature pertaining to the medical management of RHD from PubMed 1990-2016 and via selected article reference lists was reviewed. Areas included symptom management, left ventricular (LV) dysfunction, rate control in mitral stenosis (MS), atrial fibrillation (AF), anticoagulation, infective endocarditis prophylaxis and management in pregnancy...
March 30, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29606334/apical-transverse-motion-is-associated-with-interventricular-mechanical-delay-and-decreased-left-ventricular-function-in-children-with-dilated-cardiomyopathy
#12
Wei Hui, Cameron Slorach, Mark K Friedberg
BACKGROUND: Apical transverse motion (ATM) is associated with electromechanical dyssynchrony in adult dilated cardiomyopathy (DCM). Bundle branch block electromechanical dyssynchrony is uncommon in pediatric DCM, but ATM and its association with ventricular function have not been characterized. METHODS: Fifty-six children with DCM were retrospectively studied. Using echocardiography, ATM was assessed visually and by speckle-tracking longitudinal displacement of the interventricular septal and left ventricular (LV) lateral walls in opposite directions...
March 29, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29590384/atrial-remodelling-and-function-implications-for-atrial-fibrillation-surgery
#13
Stefano Benussi, Gijs E de Maat
The exact mechanism of atrial fibrillation (AF) is still incompletely understood. A number of alterations that impact focal electrical discharge, the atrial substrate and modulating factors contribute to its pathogenesis. Atrial remodelling (resulting in atrial cardiomyopathy) sets the stage for AF development. Once present, AF results in the loss of synchronized atrial contraction, which affects ventricular filling and atrial reservoir and conduit functions. Passive atrial function is particularly important in patients with left ventricular diastolic dysfunction...
April 1, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29577429/echocardiographic-advances-in-hypertrophic-cardiomyopathy-three-dimensional-and-strain-imaging-echocardiography
#14
REVIEW
Riccardo M Inciardi, Maurizio Galderisi, Stefano Nistri, Ciro Santoro, Mariantonietta Cicoira, Andrea Rossi
In the recent past, new ultrasound technologies, such as three-dimensional echocardiography and strain imaging echocardiography, raised up in clinical practice leading to a better assessment of cardiac morphology and performance. These tools may assess regional cardiac mechanics, detecting clinical and subclinical myocardial dysfunction in different settings such as ischemic heart disease, cardiomyopathies, and heart valve diseases. Interesting results derive from patients affected from hypertrophic cardiomyopathy (HCM)...
March 25, 2018: Echocardiography
https://www.readbyqxmd.com/read/29563378/infective-endocarditis-associated-with-atopic-dermatitis
#15
Shigeaki Aoyagi, Takeshi Oda, Kumiko Wada, Eiji Nakamura, Tomokazu Kosuga, Hiroshi Yasunaga
We report a case of aortic valve infective endocarditis (IE) in a 24-year-old man with atopic dermatitis (AD). He had a history of balloon valvuloplasty for a stenotic bicuspid aortic valve, and had dental caries but no invasive dental procedure before the onset of IE. On admission, skin lesions of AD with itching and scratches were found on the neck, trunk, and extremities. Echocardiography showed a vegetation on the aortic valve with mild steno-regurgitation, but extension of IE to the annulus was not detected...
March 20, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29518534/tiara-valve-implantation-in-a-patient-with-previously-implanted-mono-disk-mechanical-aortic-prosthesis
#16
Enrico Ferrari, Luigi Biasco, Francesco Faletra, Anson Cheung, Marco Moccetti, Giovanni Pedrazzini, Stefanos Demertzis, Tiziano Moccetti
Transcatheter mitral valve replacement with the Tiara valve can be performed in inoperable patients with severe functional regurgitation. Risk of left ventricular outflow tract obstruction can be prevented using preoperative 3D imaging and 3D-printed models. However, in the case of mono-disk mechanical prostheses previously implanted in aortic position (Bjork-Shiley), there is an additional risk of mechanical interference leading to reduced leaflet motion and aortic valve dysfunction. Hereafter, we describe the case of a patient with a 27-mm mono-disk mechanical aortic valve implanted in 1978, a EuroSCORE II of 18%, and a Society of Thoracic Surgeon score (mortality) of 16% who successfully underwent a transapical Tiara valve implantation...
March 5, 2018: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29485960/use-of-an-on-x-prosthetic-valve-in-a-42-year-old-female-with-antiphospholipid-syndrome
#17
Ayumi Koga, Ken Okamoto, Hirokazu Tazume, Toshihiro Fukui
Antiphospholipid syndrome is a rare autoimmune disease with a hypercoagulable state causing vascular thrombosis. We present the case of a 42-year old female who underwent mitral valve replacement with a mechanical valve 15 months ago. The postoperative course was uneventful, and echocardiography performed 14 months postoperatively showed good valve function. The patient developed sudden dyspnea 15 months postoperatively and was referred to our hospital. Echocardiography revealed mitral stenosis with stuck leaflets...
January 31, 2018: Heart Surgery Forum
https://www.readbyqxmd.com/read/29475857/comorbid-tnf-mediated-heart-valve-disease-and-chronic-polyarthritis-share-common-mesenchymal-cell-mediated-aetiopathogenesis
#18
Lydia Ntari, Maria Sakkou, Panagiotis Chouvardas, Iordanis Mourouzis, Alejandro Prados, Maria C Denis, Niki Karagianni, Constantinos Pantos, George Kollias
OBJECTIVES: Patients with rheumatoid arthritis and spondyloarthritisshow higher mortality rates, mainly caused by cardiac comorbidities. The TghuTNF (Tg197) arthritis model develops tumour necrosis factor (TNF)-driven and mesenchymalsynovial fibroblast (SF)-dependent polyarthritis. Here, we investigate whether this model develops, similarly to human patients, comorbid heart pathology and explore cellular and molecular mechanisms linking arthritis to cardiac comorbidities. METHODS: Histopathological analysis and echocardiographic evaluation of cardiac function were performed in the Tg197 model...
June 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29472025/aortic-stenosis-and-aortic-regurgitation-express-different-titin-isoforms-differences-and-relationships-with-functional-and-geometric-characteristics
#19
Vito Mannacio, Luigi Mannacio, Anita Antignano, Vincenzo De Amicis, Francesco Musumeci, Gabriele Iannelli
Background-Titin represents an important biomechanical sensor which determines compliance and diastolic/systolic function of the left ventricle (LV). To assess the different titin-isoform expression and the relationships with functional and geometric patterns, we analyzed titin-isoform expression and cardiomyocytes contractile function in myocardial biopsy samples of patients undergoing aortic valve replacement (AVR) for aortic stenosis (AS) and for aortic regurgitation (AR). Method -Specimens, collected from the LV of 35 with AS and 35 with AR undergoing AVR were analyzed for titin-isoform expression and cardiomyocytes force measurement...
May 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29460005/impact-of-pannus-formation-on-hemodynamic-dysfunction-of-prosthetic-aortic-valve-pannus-extent-and-its-relationship-to-prosthetic-valve-motion-and-degree-of-stenosis
#20
Hyun Jung Koo, Hojin Ha, Joon-Won Kang, Jeong A Kim, Jae-Kwan Song, Hwa Jung Kim, Tae-Hwan Lim, Dong Hyun Yang
BACKGROUND: Although pannus is an important cause of prosthetic valve dysfunction, the minimum pannus size that can induce hemodynamic dysfunction has not yet been determined. This study investigated the correlation between the limitation of motion (LOM) of the prosthetic valve and pannus extent and determined the pannus extent that could induce severe aortic stenosis. METHODS: This study included 49 patients who underwent mechanical aortic valve replacement (AVR) and showed pannus on cardiac computed tomography (CT)...
February 19, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
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