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abdominal aortic calcification

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https://www.readbyqxmd.com/read/28899569/on-the-influence-of-wall-calcification-and-intraluminal-thrombus-on-prediction-of-abdominal-aortic-aneurysm-rupture
#1
Hilary E Barrett, Eoghan M Cunnane, Hena Hidayat, Julie M O'Brien, Michael A Moloney, Eamon G Kavanagh, Michael T Walsh
OBJECTIVE: Parameters other than maximum diameter that predict rupture of abdominal aortic aneurysms (AAAs) may be helpful for risk-benefit analysis in individual patients. The aim of this study was to characterize the biomechanical-structural characteristics associated with AAA walls to better identify the related mechanistic variables required for an accurate prediction of rupture risk. METHODS: Anterior AAA wall (n = 40) and intraluminal thrombus (ILT; n = 114) samples were acquired from 18 patients undergoing open surgical repair...
September 9, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28888759/impact-of-iliac-artery-anatomy-on-the-outcome-of-fenestrated-and-branched-endovascular-aortic-repair
#2
Enrico Gallitto, Mauro Gargiulo, Gianluca Faggioli, Rodolfo Pini, Chiara Mascoli, Antonio Freyrie, Stefano Ancetti, Andrea Stella
OBJECTIVE: Fenestrated and branched endovascular aneurysm repair (FB-EVAR) is a valid option to treat juxtarenal and pararenal abdominal aortic aneurysms and thoracoabdominal aortic aneurysms. Because successful deployment depends on complex maneuvers, hostile iliac artery anatomy (HIA) can prejudice the FB-EVAR outcome. The aim of the study was to evaluate the impact of HIA on FB-EVAR outcome. METHODS: Between 2010 and 2015, all patients undergoing FB-EVAR were prospectively categorized according to iliac anatomy (friendly iliac artery anatomy [FIA] or HIA)...
September 6, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28885502/outcomes-of-endovascular-repair-for-abdominal-aortic-aneurysms-a-nationwide-survey-in-japan
#3
Katsuyuki Hoshina, Shin Ishimaru, Yusuke Sasabuchi, Hideo Yasunaga, Kimihiro Komori
OBJECTIVE: To analyze data on patients treated with a bifurcated stent graft for abdominal aortic aneurysm (AAA). BACKGROUND: The Japan Committee for Stentgraft Management (JACSM) was established in 2007 to manage the safety of endovascular aortic aneurysm repair (EVAR) in Japan. The JACSM registry includes detailed anatomical and clinical data of all patients who undergo stent graft insertion in Japan. METHODS: Among 51,380 patients treated with bifurcated stent graft for AAA, we identified 38,008 eligible patients (excluding those with rupture or insufficient data)...
September 6, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28870151/progression-of-arterial-stiffness-is-associated-with-changes-in-bone-mineral-markers-in-advanced-ckd
#4
Rathika Krishnasamy, Sven-Jean Tan, Carmel M Hawley, David W Johnson, Tony Stanton, Kevin Lee, David W Mudge, Scott Campbell, Grahame J Elder, Nigel D Toussaint, Nicole M Isbel
BACKGROUND: Arterial stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with chronic kidney disease (CKD). There are limited prospective data however on progression of arterial stiffness in CKD, including evaluating associations with bone mineral markers such as fibroblast growth factor 23 (FGF23) and soluble α-klotho (sKl). METHODS: In this prospective, single-center, observational study, arterial stiffness [measured by pulse wave velocity (PWV)] and hormones influencing mineral homeostasis, including serum FGF23 and sKl, were compared between non-dialysis CKD stages 4/5 and healthy controls at baseline and 12 months (12 m)...
September 4, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28760663/bilateral-endograft-limb-occlusion-after-endovascular-aortic-repair-predictive-factors-of-occurrence
#5
Konstantinos G Moulakakis, Constantine N Antonopoulos, Christos Klonaris, John Kakisis, Andreas M Lazaris, Giorgos S Sfyroeras, George Mantas, Spyridon N Mylonas, Spyridon N Vasdekis, Elias N Brountzos, George Geroulakos
BACKGROUND: Bilateral limb occlusion after endovascular aortic repair (EVAR) is relatively uncommon. The aim of this study was to investigate the incidence of bilateral endograft limb occlusion after EVAR and identify potential anatomical predictive factors of occurrence. METHODS: A total of 579 patients underwent elective EVAR for abdominal aortic aneurysm between January 2010 and December 2015. All patients presenting with unilateral and bilateral occlusions were prospectively analyzed...
July 29, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28758236/morphometric-age-and-survival-following-kidney-transplantation
#6
Michael N Terjimanian, Patrick W Underwood, David C Cron, Joshua J Augustine, Kelly A Noon, Devan A Cote, Stewart C Wang, Michael J Englesbe, Kenneth J Woodside
BACKGROUND: As patients with chronic kidney disease become older, there is greater need to identify who will most benefit from kidney transplantation. Analytic morphomics has emerged as an objective risk assessment tool distinct from chronologic age. We hypothesize that morphometric age is a significant predictor of survival following transplantation. METHODS: A retrospective cohort of 158 kidney transplant patients from 2005 to 2014 with 1-year pre-operative imaging was identified...
July 31, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28748891/study-of-chronic-kidney-disease-mineral-bone-disorders-in-newly-detected-advanced-renal-failure-patients-a-hospital-based-cross-sectional-study
#7
Praveen Kumar Etta, R K Sharma, Amit Gupta
We aim to evaluate the disturbances in mineral metabolism, abnormalities in bone mineral density (BMD), and extraskeletal calcification in newly detected, untreated predialysis stage 4 and 5 chronic kidney disease (CKD) patients at a tertiary care hospital in North India. This is cross-sectional observational study. A total of 95 (68 males, 27 females) newly detected patients underwent clinical evaluation, biochemical assessment [serum calcium, phosphorus, alkaline phosphatase (ALP), albumin, creatinine, intact parathyroid hormone (iPTH), 25- hydroxyvitamin D (25(OH)D)], BMD measurement (at spine, hip, and forearm) by dual-energy X-ray absorptiometry (DXA), lateral abdominal radiograph [for abdominal aortic calcification (AAC)], skeletal survey (to look for any abnormality including fractures), and echocardiography [for any cardiac valvular calcification (CVC)]...
July 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28745686/-effects-of-keto-amino-acids-and-a-low-protein-diet-on-the-nutritional-status-of-patients-with-stages-3b-4-chronic-kidney-disease
#8
S Yu Milovanova, Yu S Milovanov, M V Taranova, I A Dobrosmyslov
AIM: To evaluate the efficacy of keto/amino acids in maintaining protein balance and preventing mineral metabolic disturbances and the development of uremic hyperparathyroidism in the long-term use of a low-protein diet (LPD) in patients with Stages 3B-4 chronic kidney disease (CKD). SUBJECTS AND METHODS: Ninety patients with CKD caused by chronic latent glomerulonephritis in 65 patients and chronic tubulointerstitial nephritis of various etiologies (gout, drug-induced, and infection) in 25 were examined...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28743977/the-association-of-serum-adiponectin-with-abdominal-aortic-calcification-in-japanese-male-hemodialysis-patients-a-cross-sectional-observational-study
#9
Takeshi Sakura, Senji Okuno, Eriko Nishio, Kyoko Norimine, Eiji Ishimura, Tomoyuki Yamakawa, Shigeichi Shoji, Masaaki Inaba
The negative relation of serum adiponectin to atherosclerosis becomes a positive association in patients with chronic kidney disease (CKD). We conducted a small-scale cross-sectional observational study, in 101 Japanese male hemodialysis patients, to examine the relationship of serum adiponectin and leptin to abdominal aortic calcification (AAC). The presence of AAC was evaluated from simple X-ray radiographs of the left lateral abdomen. Serum adiponectin was significantly higher in AAC-positive patients [18...
July 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28682566/-vascular-calcifications-in-subjects-with-and-without-chronic-renal-failure-types-sites-and-risk-factors
#10
Annibale Marinelli, Anteo Di Napoli
Vascular calcifications worse outcomes in the general population and in patients on dialysis. We investigated 146 patients on chronic hemodialysis and 63 healthy controls with normal renal function under 65 years of age. All subjects underwent B-mode ultrasonography of common and internal carotid artery, abdominal aorta, common and superficial femoral artery and posterior tibial artery to assess the presence of intimal and medial calcifications. Intimal and media calcifications were present at the level of the carotid vessel, the abdominal aorta, the common femoral artery, the superficial femoral artery and the posterior tibial artery, respectively in 45%, 50%, 45%, 50%, 42% of patients on dialysis and in 5%, 15%, 24%, 5%, 2% of controls (p <0,01)...
April 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28662927/endovascular-treatment-of-abdominal-aortic-aneurysms-with-narrow-aortic-bifurcation-using-excluder-bifurcated-stent-grafts
#11
Pablo Marques De Marino, Isaac Martinez Lopez, Ferran Pla Sanchez, Iñaki Cernuda Artero, Maday Cabrero Fernandez, Oscar Ucles Cabeza, Francisco Javier Serrano Hernando
OBJECTIVE: This study investigated the influence of the aortic bifurcation anatomy on the endovascular treatment of abdominal aortic aneurysms using Excluder (W. L. Gore & Associates, Flagstaff, Ariz) bifurcated stent grafts. METHODS: This was a retrospective single-center study of patients treated with the Excluder stent graft. Analysis included anatomical factors of the aortic bifurcation (aortic bifurcation diameter [ABD], calcification, thrombus), characteristics of the stent graft limbs (sum of stent graft limbs diameters [SLD]), and the SLD/ABD ratio...
June 26, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28646476/the-relationship-between-circulating-adiponectin-leptin-and-vaspin-with-bone-mineral-density-bmd-arterial-calcification-and-stiffness-a-cross-sectional-study-in-post-menopausal-women
#12
N Tanna, K Patel, A E Moore, D Dulnoan, S Edwards, G Hampson
OBJECTIVE: To explore the relationship between circulating adiponectin, leptin and vaspin with bone mineral density (BMD), arterial stiffness and vascular calcification in post-menopausal women. We hypothesised that adipokines produced by adipose tissue may be mediators of bone and cardiovascular disease (CVD) and explain, in part, the observed association between osteoporosis and CVD. DESIGN: We studied 386 ambulant community dwelling postmenopausal women aged (mean [SD] 61 [6...
June 23, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28642974/abdominal-aortic-calcification-and-the-risk-of-bone-fractures-a-meta-analysis-of-prospective-cohort-studies
#13
Dailin Wei, Guanlin Zheng, Yun Gao, Jinying Guo, Tie Zhang
The relationship between abdominal aortic calcification (AAC) and bone fracture has been examined by some observational studies, but the results remain discordant. Therefore, we aimed to assess the link between them by conducting a meta-analysis of prospective studies. Relevant studies were identified by searching PubMed and EMBASE databases until the end of December 2016. Summary relative risks (RRs) and 95% confidence intervals (CIs) for associations between AAC and fracture risk were estimated with fixed- or random- effects models...
June 22, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28638171/3d-printed-abdominal-aortic-aneurysm-phantom-for-image-guided-surgical-planning-with-a-patient-specific-fenestrated-endovascular-graft-system
#14
Karen M Meess, Richard L Izzo, Maciej L Dryjski, Richard E Curl, Linda M Harris, Michael Springer, Adnan H Siddiqui, Stephen Rudin, Ciprian N Ionita
Following new trends in precision medicine, Juxatarenal Abdominal Aortic Aneurysm (JAAA) treatment has been enabled by using patient-specific fenestrated endovascular grafts. The X-ray guided procedure requires precise orientation of multiple modular endografts within the arteries confirmed via radiopaque markers. Patient-specific 3D printed phantoms could familiarize physicians with complex procedures and new devices in a risk-free simulation environment to avoid periprocedural complications and improve training...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28614411/focal-induction-of-ros-release-to-trigger-local-vascular-degeneration
#15
Jan-Philipp Minol, Isabella Reinsch, Maximilian Luik, Anne Leferink, Mareike Barth, Alexander Assmann, Artur Lichtenberg, Payam Akhyari
Reactive oxygen species (ROS) play an important role in the process of cardiovascular degeneration. We evaluated the potential of a controlled, local induction of ROS-release by application of rose bengal (RB) and photo energy to induce atherosclerosis-like focal vascular degeneration in vivo. After injection of RB, rats fed with a pro-degenerative diet underwent focal irradiation of the abdominal aorta by a green laser (ROS group), while the controls received irradiation without RB. Aortic tissue was analyzed by histology and immunohistochemistry at 0, 2, 4, 8, 28 and 56 days (n = 5)...
2017: PloS One
https://www.readbyqxmd.com/read/28605936/vascular-disease-and-kidney-stones-abdominal-aortic-calcifications-are-associated-with-low-urine-ph-and-hypocitraturia
#16
Nishant D Patel, Ryan D Ward, Juan Calle, Erick M Remer, Manoj Monga
OBJECTIVE: Vascular calcifications are associated with nephrolithiasis. Although studies have demonstrated correlations with vascular disease and calcium stones in kidney stone formers (KSF), an etiologic link has remained elusive. As a noncontrast CT (NCCT) scan is typically part of a stone evaluation, our objective was to evaluate the association of NCCT-based assessment of abdominal aortic calcifications (AACs) with 24-hour urine parameters and stone composition. MATERIALS AND METHODS: Ninety-seven KSF were included with CT imaging and 24-hour urine studies...
July 7, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28552661/30years-of-dxa-technology-innovations
#17
Claus-C Glüer
As the successor of Dual Photon Absorptiometry (DPA), Dual X-ray Absorptiometry (DXA) has seen 30years of continuous technological innovations. Implementation of measures for standardization and quality assurance made DXA a reliable and clinically useful approach. Its use in clinical multicenter drug studies in osteoporosis lead to general acceptance as the standard technique of bone densitometry. The limitations of DXA are well established. As a measure of areal bone mineral density (aBMD) it depends on bone size and is biased by overlaying soft tissue and calcified structures...
May 24, 2017: Bone
https://www.readbyqxmd.com/read/28547671/is-coronary-calcium-scoring-too-late-total-body-arterial-calcium-burden-in-patients-without-known-cad-and-normal-mpi
#18
Adel H A Allam, Randall C Thompson, Michael A Eskander, Mohamed A Mandour Ali, Ayman Sadek, Chris J Rowan, M Linda Sutherland, James D Sutherland, Bruno Frohlich, David E Michalik, Caleb E Finch, Jagat Narula, Gregory S Thomas, L Samuel Wann
BACKGROUND: Patients with normal myocardial perfusion imaging (MPI) have a good prognosis. However, pre-clinical coronary and extracoronary atherosclerosis may exist in the absence of myocardial ischemia. METHODS: 154 Egyptian patients (mean age 53 years) underwent whole-body non-contrast CT following normal MPI. RESULTS: Atherosclerosis in the form of calcification was observed in ≥1 vascular bed in 115 of 154 (75%) patients. This included the iliofemoral (62%), abdominal aorta (53%), thoracic aorta (47%), coronary (47%), and carotid (25%) vascular beds...
May 25, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28486844/a-real-world-experience-comparison-of-percutaneous-and-open-femoral-exposure-for-endovascular-abdominal-aortic-aneurysm-repair-in-a-tertiary-medical-center
#19
MULTICENTER STUDY
Dipankar Mukherjee, Erica Emery, Rashad Majeed, Keyvan Heshmati, Homayoun Hashemi
OBJECTIVE: To compare the outcomes of elective percutaneous endovascular aneurysm repair (PEVAR) versus surgical cutdown endovascular aneurysm repair (SEVAR) procedures performed at a tertiary medical center from 2012 to 2015. METHODS: This is a unique study using procedure data from two vascular surgeons who performed SEVAR in almost every case versus three vascular surgeons who performed PEVAR in all cases except when considered prohibitive on account of circumferential calcification or severe occlusive disease of the common femoral artery or some other technical consideration...
July 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28479451/prognostic-value-of-aortoiliac-calcification-score-in-kidney-transplantation-recipients
#20
Bertrand Chavent, Nicolas Maillard, Claire Boutet, Jean-Noël Albertini, Ambroise Duprey, Jean-Pierre Favre
BACKGROUND: Kidney recipients are increasingly older with arterial disease and extended arterial calcifications. In a kidney transplantation population, the prognosis value of aortic and iliac calcifications remains poorly explored. We aimed to assess the impact of pre-transplantation Aortoiliac vascular calcifications on patients, grafts survival and cardiovascular events. METHODS: This retrospective study included kidney transplantation patients from 2006 to 2012 for whom we had available pre-surgery abdominal computed tomography results (n=100)...
May 4, 2017: Annals of Vascular Surgery
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