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https://www.readbyqxmd.com/read/28453258/study-of-lithium-silicide-nanoparticles-as-anode-materials-for-advanced-lithium-ion-batteries
#1
Xuemin Li, Faith E Kersey-Bronec, John Ke, Jacqueline E Cloud, Yonglong Wang, Chilan Ngo, Svitlana Pylypenko, Yongan Yang
The development of high-performance silicon (Si) anodes for the next generation of lithium ion batteries (LIBs) evokes increasing interest in studying its lithiated counterpart - lithium silicide (LixSi). This article reports a systematic study of three thermodynamically-stable phases of LixSi (x = 4.4, 3.75, and 2.33) plus nitride-protected Li4.4Si, which are synthesized via the high-energy ball milling technique. All three LixSi phases show improved performance over unmodified Si, where Li4.4Si demonstrates optimum performance with discharging capacity of 3306 mAh/g initially and maintained above 2100 mAh/g for over 30 cycles and above 1200 mAh/g for over 60 cycles at the current density of 358 mA/g-Si...
April 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28449236/discovery-of-lhrh-and-development-of-lhrh-analogs-for-prostate-cancer-treatment
#2
Andrew V Schally, Norman L Block, Ferenc G Rick
The discovery, isolation, elucidation of structure, synthesis, and initial testing of the neuropeptide hypothalamic luteinizing hormone-releasing hormone (LHRH), which regulates reproduction, is briefly described. The design, synthesis, and experimental and clinical testing of agonistic analogs of LHRH is extensively reviewed focusing on the development of new methods for the treatment of prostate cancer. Subsequent development of antagonistic analogs of LHRH is then faithfully recounted with special emphasis on therapy of prostate cancer and BPH...
April 27, 2017: Prostate
https://www.readbyqxmd.com/read/28446765/three-dimensional-modeling-of-single-stranded-dna-hairpins-for-aptamer-based-biosensors
#3
Iman Jeddi, Leonor Saiz
Aptamers consist of short oligonucleotides that bind specific targets. They provide advantages over antibodies, including robustness, low cost, and reusability. Their chemical structure allows the insertion of reporter molecules and surface-binding agents in specific locations, which have been recently exploited for the development of aptamer-based biosensors and direct detection strategies. Mainstream use of these devices, however, still requires significant improvements in optimization for consistency and reproducibility...
April 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28446146/flow-cytometry-sorting-of-nuclei-enables-the-first-global-characterization-of-paramecium-germline-dna-and-transposable-elements
#4
Frédéric Guérin, Olivier Arnaiz, Nicole Boggetto, Cyril Denby Wilkes, Eric Meyer, Linda Sperling, Sandra Duharcourt
BACKGROUND: DNA elimination is developmentally programmed in a wide variety of eukaryotes, including unicellular ciliates, and leads to the generation of distinct germline and somatic genomes. The ciliate Paramecium tetraurelia harbors two types of nuclei with different functions and genome structures. The transcriptionally inactive micronucleus contains the complete germline genome, while the somatic macronucleus contains a reduced genome streamlined for gene expression. During development of the somatic macronucleus, the germline genome undergoes massive and reproducible DNA elimination events...
April 26, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28435813/medical-care-or-disciplinary-discourses-preventive-measures-against-the-black-death-in-late-medieval-paris-a-brief-review
#5
REVIEW
Yong Jin Hong, Sam Hun Park
BACKGROUND: This paper examined the political and social implications of the Compendium de epidemia prescription written by the Masters of the Faculty of Medicine of the University of Paris in the mid-14th century during the Black Death. This study aimed to examine how the effects of power as a discourse owned by medical knowledge are revealed. METHODS: This paper outlines the composition of the contents based on the 1888 edition edited and translated by Émile H...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28435756/identifying-barriers-in-the-use-of-electronic-health-records-in-hawai-i
#6
Faith D Hamamura, Kelley Withy, Kira Hughes
Hawai'i faces unique challenges to Electronic Health Record (EHR) adoption due to physician shortages, a widespread distribution of Medically Underserved Areas and Populations (MUA/P), and a higher percentage of small independent practices. However, research on EHR adoption in Hawai'i is limited. To address this gap, this article examines the current state of EHR in Hawai'i, the barriers to adoption, and the future of Health Information Technology (HIT) initiatives to improve the health of Hawai'i's people...
March 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28431262/immunologic-approaches-for-the-treatment-of-multiple-myeloma
#7
REVIEW
Leo Rasche, Niels Weinhold, Gareth J Morgan, Frits van Rhee, Faith E Davies
The FDA approval of two monoclonal antibodies in 2015has heralded a new era of targeted immunotherapies for multiple myeloma (MM). In this review we discuss the recent approaches using different immunological components to treat MM. In particular, we review current monoclonal antibody based therapies, engineered T- and NK cell products, 'off-target' immunomodulation, and strategies utilizing allogeneic cell transplantation in MM. We discuss how an immunologic approach offers promise for the treatment of this genetically heterogeneous disease, and how patients with acquired drug resistance may particularly benefit from these therapies...
April 6, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28424704/draco-stem-an-automatic-tool-to-generate-high-quality-3d-meshes-of-shoot-apical-meristem-tissue-at-cell-resolution
#8
Guillaume Cerutti, Olivier Ali, Christophe Godin
Context: The shoot apical meristem (SAM), origin of all aerial organs of the plant, is a restricted niche of stem cells whose growth is regulated by a complex network of genetic, hormonal and mechanical interactions. Studying the development of this area at cell level using 3D microscopy time-lapse imaging is a newly emerging key to understand the processes controlling plant morphogenesis. Computational models have been proposed to simulate those mechanisms, however their validation on real-life data is an essential step that requires an adequate representation of the growing tissue to be carried out...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28420788/reconstructing-the-spectrotemporal-modulations-of-real-life-sounds-from-fmri-response-patterns
#9
Roberta Santoro, Michelle Moerel, Federico De Martino, Giancarlo Valente, Kamil Ugurbil, Essa Yacoub, Elia Formisano
Ethological views of brain functioning suggest that sound representations and computations in the auditory neural system are optimized finely to process and discriminate behaviorally relevant acoustic features and sounds (e.g., spectrotemporal modulations in the songs of zebra finches). Here, we show that modeling of neural sound representations in terms of frequency-specific spectrotemporal modulations enables accurate and specific reconstruction of real-life sounds from high-resolution functional magnetic resonance imaging (fMRI) response patterns in the human auditory cortex...
April 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28419126/availability-and-affordability-of-antimalarial-and-antibiotic-medicines-in-malawi
#10
Felix Khuluza, Lutz Heide
BACKGROUND: Availability and affordability of medicines are key determinants of universal health coverage, yet achieving them presents a major challenge especially in low-income countries. We here present an analysis of availability and prices of antimalarial and antibiotic medicines in public, faith-based and private health facilities in Malawi. Medicines are provided free of charge in the public health care system of Malawi. In contrast, facilities of the Christian Health Association of Malawi (CHAM) usually charge their patients for medicines, as do private for-profit facilities...
2017: PloS One
https://www.readbyqxmd.com/read/28411345/an-appraisal-of-the-learning-curve-in-robotic-general-surgery
#11
Luise I M Pernar, Faith C Robertson, Ali Tavakkoli, Eric G Sheu, David C Brooks, Douglas S Smink
BACKGROUND: Robotic-assisted surgery is used with increasing frequency in general surgery for a variety of applications. In spite of this increase in usage, the learning curve is not yet defined. This study reviews the literature on the learning curve in robotic general surgery to inform adopters of the technology. METHODS: PubMed and EMBASE searches yielded 3690 abstracts published between July 1986 and March 2016. The abstracts were evaluated based on the following inclusion criteria: written in English, reporting original work, focus on general surgery operations, and with explicit statistical methods...
April 14, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28408119/ecological-validity-of-cost-effectiveness-models-of-universal-hpv-vaccination-a-systematic-literature-review
#12
REVIEW
Giampiero Favato, Tania Easton, Riccardo Vecchiato, Emmanouil Noikokyris
BACKGROUND: The protective (herd) effect of the selective vaccination of pubertal girls against human papillomavirus (HPV) implies a high probability that one of the two partners involved in intercourse is immunised, hence preventing the other from this sexually transmitted infection. The dynamic transmission models used to inform immunisation policy should include consideration of sexual behaviours and population mixing in order to demonstrate an ecological validity, whereby the scenarios modelled remain faithful to the real-life social and cultural context...
May 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28405986/assessment-of-compliance-to-treatment-of-diabetes-and-hypertension-amongst-previously-diagnosed-patients-from-rural-community-of-raigad-district-of-maharashtra
#13
Kiranmayi Venkata Kakumani, Prasad Waingankar
INTRODUCTION: Substantial burden of diabetes and hypertension is on rise in India, leading to a twin epidemic. India, being a rural country, has unique problems regarding the treatment compliance which is a serious risk for morbidity and mortality. OBJECTIVE: To assess the compliance to treatment of hypertension and diabetes amongst the diagnosed patients from rural area and to study reasons of non-compliance and knowledge and attitude. MATERIAL AND METHODS: Community based, cross sectional, observational study conducted in the rural communities of Tara and Barapada villages of Raigad district of Maharashtra...
December 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28401491/faith-based-institutions-as-venues-for-obesity-prevention
#14
REVIEW
Maria J Maynard
PURPOSE OF REVIEW: The aim of this current narrative review is to critique the scope and value of recent studies with a focus on obesity-related health promotion in faith organizations. RECENT FINDINGS: Electronic database searches, scanning of the reference lists of identified articles, and hand searching of journals for articles written in English and published in 2013-2016 revealed 16 studies. Half of the studies involved African-Americans, in churches and with predominantly female participants...
April 11, 2017: Current Obesity Reports
https://www.readbyqxmd.com/read/28399003/a-comprehensive-response-the-role-of-nonstate-actors-in-the-global-plan
#15
Robert J Vitillo, Francesca Merico, Anna S Levine, Taylor Buonocore
Nonstate actors-especially faith-based organizations, other nongovernmental organizations, groups of people living with HIV and AIDS, and private sector organizations-have been deeply committed to supporting governments reach the goals of the Global Plan Towards the Elimination of New HIV Infections Among Children by 2015 and Keeping Their Mothers Alive (Global Plan). This article highlights the role and contributions of select faith-based organizations and some private sector and philanthropic partners, as well as the work of other organizations...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28394728/destroying-false-images-of-god-the-experiences-of-lgbt-catholics
#16
Angele Deguara
This paper is about how lesbian, gay, bisexual and trans (LGBT) Catholics imagine God1(1) and how images of God change in parallel with their self-image. The study is based on qualitative research with LGBT Catholics most of whom are members of Drachma LGBTI in Malta or Ali d'Aquila in Palermo, Sicily. LGBT Catholics' image of God changes as they struggle to reconcile their religious and sexual identities, as they go through a process of "conversion" from deviants and sinners to loved children of God. One study participant compares his faith in God to peeling an onion: "With every layer one peels off, one destroys false images of God...
April 10, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28386544/use-of-nanoparticles-as-contrast-agents-for-the-functional-and-molecular-imaging-of-abdominal-aortic-aneurysm
#17
REVIEW
Theophilus I Emeto, Faith O Alele, Amy M Smith, Felicity M Smith, Tammy Dougan, Jonathan Golledge
Abdominal aortic aneurysm (AAA) is a degenerative disease of the aorta common in adults older than 65 years of age. AAA is usually imaged using ultrasound or computed tomography. Molecular imaging technologies employing nanoparticles (NPs) have been proposed as novel ways to quantify pathological processes, such as inflammation, within AAAs as a means to identify the risk of rapid progression or rupture. This article reviews the current evidence supporting the role of NP-based imaging in the management of AAA...
2017: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28380957/development-of-a-beam-optimization-method-for-absorption-based-tomography
#18
Tao Yu, Bo Tian, Weiwei Cai
Absorption tomography is an imaging technique that has been used simultaneously to image multiple scalar parameters, such as temperature and species concentration for combustion diagnostics. Practical combustors, such as internal combustion engines and gas turbine engines, only allow limited optical access, and typically a few (ca. 20-40) beams are available to probe the domain of interest. With such limited spatial sampling, it is non-trivial to optimize beam arrangement for a faithful reconstruction. Previous efforts on beam optimization rely on either heuristic/empirical methods lacking rigorous mathematical derivation or were derived by assuming certain prior information in the tomographic inversion...
March 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28380714/accessing-faith-based-organizations-using-public-transportation
#19
Terri Lewinson, Olivia Maley, Ann-Margaret Esnard
Nondriving aging adults are at risk of experiencing mobility barriers that inhibit access to important community resources for managing health and wellbeing. This multimethod study explores bus transportation experiences of older adults who live in extended stay hotels and use faith-based organizations to access resources. Interviews from 17 nondriving older adults were analyzed for perspectives about using faith-based organizations and residents' experiences navigating to faith-based organizations through available bus transportation in their communities...
January 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28380627/promoting-cancer-screening-among-churchgoing-latinas-fe-en-acci%C3%A3-n-faith-in-action
#20
J P Elder, J Haughton, L G Perez, M E Martínez, C L De la Torre, D J Slymen, E M Arredondo
Cancer screening rates among Latinas are generally low, reducing the likelihood of early cancer detection in this population. This article examines the effects of a community intervention (Fe en Acción/Faith in Action) led by community health workers (promotoras) on promoting breast, cervical and colorectal cancer screening among churchgoing Latinas. Sixteen churches were randomly assigned to a cancer screening or a physical activity intervention. We examined cancer knowledge, barriers to screening and self-reported mammography, clinical breast exam, Pap test, fecal occult blood test and sigmoidoscopy or colonoscopy at baseline and 12 months follow-up...
April 1, 2017: Health Education Research
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