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https://www.readbyqxmd.com/read/28822144/-progress-in-research-for-pharmacological-effects-of-pu-erh-tea
#1
REVIEW
Xiao-Pan Gu, Bo Pan, Zhen Wu, Yun-Fang Zhao, Peng-Fei Tu, Jiao Zheng
Pu-erh tea has gradually aroused general concern with social development and people's enhanced awareness of health. Pu-erh tea is rich in multiple active constitute such as flavonoids, catechins, phenolic acids, flavanols polymer, purine alkaloids, and hydrolysable tannin as a microbial-fermented tea.It is reported that Pu-erh tea have a variety of pharmacologically activities, such as anti-hyperlipidemic, anti-diabetic, anti-oxidative, anti-tumor, anti-bacterial, anti-inflammatory, and anti-viral effects. In this paper, the main pharmacological effects of Pu-erh tea are reviewed...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28821789/isolation-characterization-and-toxicological-potential-of-alternaria-mycotoxins-tea-aoh-and-ame-in-different-alternaria-species-from-various-regions-of-india
#2
Mukesh Meena, Prashant Swapnil, R S Upadhyay
Alternaria species produce various sorts of toxic metabolites during their active growth and causes severe diseases in many plants by limiting their productivity. These toxic metabolites incorporate various mycotoxins comprising of dibenzo-α-pyrone and some tetramic acid derivatives. In this study, we have screened out total 48 isolates of Alternaria from different plants belonging to different locations in India, on the basis of their pathogenic nature. Pathogenicity testing of these 48 strains on susceptible tomato variety (CO-3) showed 27...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28820236/regulatory-mechanism-of-mycotoxin-tenuazonic-acid-production-in-pyricularia-oryzae
#3
Choong-Soo Yun, Takayuki Motoyama, Hiroyuki Osada
Tenuazonic acid (TeA) is a mycotoxin produced by the rice blast fungus Pyricularia oryzae and some plant pathogenic fungi. We previously demonstrated that TeA is biosynthesized in P. oryzae by TeA synthetase 1 (TAS1), and that its production is induced by osmo-sensory MAPK-encoding gene (OSM1) deletion or the addition of 1% DMSO to cultures; however, the regulatory mechanisms of TeA production were unknown. Here, we identified a Zn(II)2-Cys6-type transcription factor in the upstream region of TAS1, which is encoded by TAS2 and regulates TeA production...
August 18, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/28818687/consumer-exposure-to-certain-ingredients-of-cosmetic-products-the-case-for-tea-tree-oil
#4
Bernhard O Rieder
Reliable exposure data are essential to evaluate the safety of ingredients in cosmetics. The study reported here was carried out on behalf of the Australian Tea Tree Industry Association in order to support safety assessment of TTO in consumer cosmetic products. Data regarding the use of TTO-containing cosmetic products were collected through a web-survey among 2535 qualified users of validated TTO-containing cosmetics in 5 European countries. Data regarding the percentage of TTO present in the individual products (TTO-inclusion) were collected from the suppliers of those products...
August 14, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28815936/combinatorial-effect-of-nicotine-and-black-tea-on-heart-rate-variability-useful-or-harmful
#5
S Joukar, M Sheibani
The effect of nicotine on heart rate variability (HRV) is controversial. Autonomic nervous system is the main regulator of heart rhythm, and heart rate variability is an appropriate index to assessment of the effects of the autonomic system on heart. In this study, the combination effect of nicotine and black tea consumption on sympatho-vagal balance and heart rate variability was investigated in rats. Male Wistar rats were randomized into four groups as control, tea (2.5 g/100 cc, daily), nicotine (2 mg/kg/d) and tea plus nicotine groups which treated for 28 days, and in the 29th day, their electrocardiograms (lead II) were recorded...
June 2017: Autonomic & Autacoid Pharmacology
https://www.readbyqxmd.com/read/28815601/antimicrobial-synergism-and-cytotoxic-properties-of-citrus-limon-l-piper-nigrum-l-and-melaleuca-alternifolia-maiden-and-betche-cheel-essential-oils
#6
Miloš M Nikolić, Katarina K Jovanović, Tatjana Lj Marković, Dejan Lj Marković, Nevenka N Gligorijević, Siniša S Radulović, Marina Kostić, Jasmina M Glamočlija, Marina D Soković
OBJECTIVES: The chemical composition, antimicrobial and synergistic effect, and cytotoxic activity of Citrus limon (lemon), Piper nigrum (green pepper) and Melaleuca alternifoila (tea tree) essential oils (EOs) were investigated. METHODS: Chemical analyses of essential oils were tested by GC-FID and GC-MS spectroscopy. The antimicrobial activity assay was conducted using microdilution method against several oral bacteria and Candida spp. originating from the humans with oral disorders...
August 17, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28814987/green-tea-polyphenols-ameliorate-the-early-renal-damage-induced-by-a-high-fat-diet-via-ketogenesis-sirt3-pathway
#7
Weijie Yi, Xiao Xie, Miying Du, Yongjun Bu, Nannan Wu, Hui Yang, Chong Tian, Fangyi Xu, Siyun Xiang, Piwei Zhang, Zhuo Chen, Xuezhi Zuo, Chenjiang Ying
SCOPE: Several reports in the literature have suggested the renoprotective effects of ketone bodies and green tea polyphenols (GTPs). Our previous study found that GTP consumption could elevate the renal expression of the ketogenic rate-limiting enzyme, which was decreased by a high-fat diet (HFD) in rats. Here, we investigated whether ketogenesis can mediate renoprotection by GTPs against an HFD. METHODS AND RESULTS: Wistar rats were fed a standard or HFD with or without GTPs for 18 weeks...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28813453/metabolomics-reveals-that-vine-tea-ampelopsis-grossedentata-prevents-high-fat-diet-induced-metabolism-disorder-by-improving-glucose-homeostasis-in-rats
#8
Wenting Wan, Baoping Jiang, Le Sun, Lijia Xu, Peigen Xiao
BACKGROUND: Vine tea (VT), derived from Ampelopsis grossedentata (Hand.-Mazz.) W.T. Wang, is an alternative tea that has been consumed widely in south China for hundreds of years. It has been shown that drinking VT on a daily basis improves hyperlipidemia and hyperglycemia. However, little is known about the preventive functions of VT for metabolic dysregulation and the potential pathological mechanisms involved. This paper elucidates the preventive effects of VT on the dysregulation of lipid and glucose metabolism using rats maintained on a high-fat-diet (HFD) in an attempt to explain the potential mechanisms involved...
2017: PloS One
https://www.readbyqxmd.com/read/28813122/morphological-alterations-in-the-jejunal-mucosa-of-aged-rats-and-the-possible-protective-role-of-green-tea
#9
Zeinab Abel-Rehim Hassan, Agata Zauszkiewicz-Pawlak, Shaimaa A Abdelrahman, Sami Algaidi, Maha Desouky, Sally M Shalaby
INTRODUCTION: Gastrointestinal disorders become more prevalent with ageing. This study is aimed to describe morphological changes that occur in the jejunal mucosa of male albino rats as a result of ageing and the protective effect of green tea supplements. MATERIAL AND METHODS: The experiment was performed on sixty rats: thirty young-adult (6-month old, body mass 200-220 g) and thirty old (24-month-old, body mass 220-260 g) animals. Each group was further divided into two subgroups (n = 15 each): control rats and green tea-treated rats that received 1...
August 16, 2017: Folia Histochemica et Cytobiologica
https://www.readbyqxmd.com/read/28812379/dietary-polyphenols-for-atherosclerosis-a-comprehensive-review-and-future-perspectives
#10
Roodabeh Bahramsoltani, Farnaz Ebrahimi, Mohammad Hosein Farzaei, Armaghan Baratpourmoghaddam, Pardis Ahmadi Borkani, Pourouchista Rostamiasrabadi, Amir Hosein Rasouli Amirabadi, Roja Rahimi
Atherosclerosis is one of the most prevalent reasons for premature death in adults. Despite the several conventional drugs in the market; many patients are not completely treated. Here we comprehensively review current clinical evidence regarding the efficacy of dietary polyphenols in atherosclerosis and related complications. PubMed, Cochrane library and Scopus were searched from inception until August 2016 to obtain clinical trials in which polyphenols were evaluated in cardiovascular parameters related to atherosclerosis...
August 16, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28812322/reactivity-of-silanes-with-tbuponop-ruthenium-dichloride-facile-synthesis-of-chloro-silyl-ruthenium-compounds-and-subsequent-reactivity
#11
James Matthew Boncella, Nickolas H Anderson, Aaron M Tondreau
The coordination of tBuPONOP (tBuPONOP = 2,6-bis(ditertbutylphosphinito)pyridine) to different ruthenium starting materials, to generate (tBuPONOP)RuCl2, was investigated. The 16-electron species (tBuPONOP)Ru(H)Cl was produced from the reaction of triethylsilane with (tBuPONOP)RuCl2. Reactions of (tBuPONOP)RuCl2 with both phenylsilane or diphenylsilane afforded the 16-electron hydrido-silyl species (tBuPONOP)Ru(H)(PhSiCl2) and (tBuPONOP)Ru(H)(Ph2SiCl), respectively. Reactions of all three of these complexes with silver triflate afforded the simple salt metathesis products of (tBuPONOP)Ru(H)(OTf), (tBuPONOP)Ru(H)(PhSiCl(OTf)), and (tBuPONOP)Ru(H)(Ph2Si(OTf))...
August 15, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28811706/therapeutic-potential-of-flavonoids-in-inflammatory-bowel-disease-a-comprehensive-review
#12
REVIEW
Ali Salaritabar, Behrad Darvishi, Farzaneh Hadjiakhoondi, Azadeh Manayi, Antoni Sureda, Seyed Fazel Nabavi, Leo R Fitzpatrick, Seyed Mohammad Nabavi, Anupam Bishayee
The inflammatory process plays a central role in the development and progression of numerous pathological situations, such as inflammatory bowel disease (IBD), autoimmune and neurodegenerative diseases, metabolic syndrome, and cardiovascular disorders. IBDs involve inflammation of the gastrointestinal area and mainly comprise Crohn's disease (CD) and ulcerative colitis (UC). Both pathological situations usually involve recurring or bloody diarrhea, pain, fatigue and weight loss. There is at present no pharmacological cure for CD or UC...
July 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28811513/altered-cerebellar-biochemical-profiles-in-infants-born-prematurely
#13
Marie Brossard-Racine, Jonathan Murnick, Marine Bouyssi-Kobar, Janie Coulombe, Taeun Chang, Catherine Limperopoulos
This study aims to compare the cerebellar biochemical profiles in preterm (PT) infants evaluated at term equivalent age (TEA) and healthy full-term newborns using proton magnetic resonance spectroscopy ((1)H-MRS). We explore the associations between altered cerebellar metabolite profiles and brain injury topography, severity of injury, and prematurity-related clinical complications. We prospectively collected high quality (1)H-MRS in 59 premature infants born ≤32 weeks and 61 healthy full term controls. (1)H-MRS data were processed using LCModel software to calculate absolute metabolite concentration for N-acetyl-aspartate (NAA), choline (Cho) and creatine (Cr)...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809447/pulmonary-delivery-of-tea-tree-oil-%C3%AE-cyclodextrin-inclusion-complexes-for-the-treatment-of-fungal-and-bacterial-pneumonia
#14
Miao Li, Lifei Zhu, Tongtong Zhang, Boming Liu, Lina Du, Yiguang Jin
OBJECTIVES: Bacterial pneumonia is a common cause of death worldwide. Tea tree oil (TTO) is a potent antimicrobial natural product, which is formulated in dry powder inhalers (DPIs) for the treatment of fungal and bacterial pneumonia. METHODS: Tea tree oil-β-cyclodextrin inclusion complexes (TTO-β-CD) were prepared and characterized. Aerodynamic properties of TTO-β-CD powders were measured. The rat models of fungal (Candida albicans) and bacterial (Acinetobacter baumannii) pneumonia were prepared...
August 15, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28808779/optimisation-of-extraction-methods-and-quantification-of-benzo-a-pyrene-and-benz-a-anthracene-in-yerba-mat%C3%A3-tea-by-isotope-dilution-mass-spectrometry
#15
Ee Mei Gui, Ting Lu, Tang Lin Teo, Pui Sze Cheow, Tong Kooi Lee
A gas chromatography-isotope dilution mass spectrometry (GC-IDMS) technique was developed for the quantification of two heavy polyaromatic hydrocarbons (PAHs), benz[a]anthracene and benzo[a]pyrene, in yerba maté tea (maté). The optimisation of two extraction methods, namely liquid-liquid extraction and accelerated solvent extraction, was carried out. Both optimised methods were validated using a certified reference material of fine dust and the results were within the expanded uncertainties at 95% confidence level...
August 14, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28808309/defluoridation-technology-for-drinking-water-and-tea-by-green-synthesized-fe3o4-al2o3-nanoparticles-coated-polyurethane-foams-for-rural-communities
#16
Sonu Kumari, Suphiya Khan
Fluoride (F) contaminated ground water poses a serious public health concern to rural population with unaffordable purification technologies. Therefore, development of a cost-effective, portable, environment and user-friendly defluoridation technique is imperative. In the present study, we report on the development of a green and cost-effective method that utilizes Fe3O4 and Al2O3 nanoparticles (NPs) that were synthesized using jojoba defatted meal. These NPs were impregnated on to polyurethane foam (PUF) and made into tea infusion bags...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28807853/aqueous-extract-from-pecan-nut-carya-illinoinensis-wangenh-c-koch-shell-show-activity-against-breast-cancer-cell-line-mcf-7-and-ehrlich-ascites-tumor-in-balb-c-mice
#17
Josiane Hilbig, Priscila de Britto Policarpi, Valdelúcia Maria Alves de Souza Grinevicius, Nádia Sandrine Ramos Santos Mota, Rozangela Curi Pedrosa, Jane Mara Block
ETHNOPHARMACOLOGICAL RELEVANCE: In Brazil, use of teas are common for the treatment of many health disorders. Shell extracts of pecan nut (Carya illinoinensis) are popularly taken as tea to prevent diverse pathologies due to their phytochemical composition presenting significant amounts of phenolic substances. AIM OF THE STUDY: Phenolic compounds from pecan nut shell extract have been associated with diverse biological effects but the effect on tumor cells has not been reported yet...
August 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28806859/analysis-of-low-molecular-weight-compounds-using-maldi-and-ldi-tof-ms-direct-detection-of-active-pharmaceutical-ingredients-in-different-formulations
#18
João L Bronzel, Cintia D F Milagre, Humberto M S Milagre
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) is a high throughput, easy to use analytical technique. The simple sample preparation of this technique and its tolerance to the presence of contaminants are among its advantages. In contrast, depending on the matrix used, MALDI can ionize and generates ions in the low m/z range that complicate the interpretation of the spectra of low molecular weight compounds. To address this issue, one can envisage the use of tunable ionic matrices that can reduce the low m/z interferents...
August 14, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28806066/thiol-mediated-synthesis-of-hyaluronic-acid-epigallocatechin-3-o-gallate-conjugates-for-the-formation-of-injectable-hydrogels-with-free-radical-scavenging-property-and-degradation-resistance
#19
Chixuan Liu, Ki Hyun Bae, Atsushi Yamashita, Joo Eun Chung, Motoichi Kurisawa
Hyaluronic acid (HA)-based biomaterials have demonstrated only limited in vivo stability as a result of rapid degradation by hyaluronidase and reactive oxidative species. The green tea catechin, (-)-epigallocatechin-3-O-gallate (EGCG), has received considerable attention because of its powerful antioxidant and enzyme-inhibitory activities. We describe here the synthesis of HA-EGCG conjugate using a thiol-mediated reaction and its use for the preparation of a long-lasting injectable hydrogel. HA-EGCG conjugates with tunable degrees of substitution were synthesized by the nucleophilic addition reaction between EGCG quinone and thiolated HA under mild conditions...
August 14, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28805780/-regional-and-peripheral-blockades-for-prevention-of-chronic-post-thoracotomy-pain-syndrome-in-oncosurgical-practice
#20
V E Khoronenko, A S Malanova, D S Baskakov, A B Ryabov, O V Pikin
AIM: To compare an effectiveness of thoracic epidural anesthesia/analgesia, paravertebral and intercostal blockades in prevention of chronic post-thoracotomy pain syndrome (CPTPS) in oncosurgery. MATERIAL AND METHODS: There were 300 patients who underwent open surgery including lobectomy or pneumonectomy. Patients were randomized into 3 groups depending on type of anesthesia: TEA (n=100) - combined general and epidural anesthesia; PVB (n=50) - combined general and paravertebral anesthesia; ICB (n=50) - general anesthesia was supplemented by intercostal blockade after removal of the drug...
2017: Khirurgiia
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