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https://www.readbyqxmd.com/read/28448529/a-genome-wide-analysis-of-the-rna-guided-silencing-pathway-in-coffee-reveals-insights-into-its-regulatory-mechanisms
#1
Christiane Noronha Fernandes-Brum, Pâmela Marinho Rezende, Thales Henrique Cherubino Ribeiro, Raphael Ricon de Oliveira, Thaís Cunha de Sousa Cardoso, Laurence Rodrigues do Amaral, Matheus de Souza Gomes, Antonio Chalfun-Junior
microRNAs (miRNAs) are derived from self-complementary hairpin structures, while small-interfering RNAs (siRNAs) are derived from double-stranded RNA (dsRNA) or hairpin precursors. The core mechanism of sRNA production involves DICER-like (DCL) in processing the smallRNAs (sRNAs) and ARGONAUTE (AGO) as effectors of silencing, and siRNA biogenesis also involves action of RNA-Dependent RNA Polymerase (RDR), Pol IV and Pol V in biogenesis. Several other proteins interact with the core proteins to guide sRNA biogenesis, action, and turnover...
2017: PloS One
https://www.readbyqxmd.com/read/28446037/caffeine-coffee-and-appetite-control-a-review
#2
Matthew M Schubert, Christopher Irwin, Rebekah F Seay, Holly E Clarke, Deanne Allegro, Ben Desbrow
Coffee and caffeine consumption has global popularity. However, evidence for the potential of these dietary constituents to influence energy intake, gut physiology, and appetite perceptions remains unclear. The purpose of this review was to examine the evidence regarding coffee and caffeine's influence on energy intake and appetite control. The literature was examined for studies that assessed the effects of caffeine and coffee on energy intake, gastric emptying, appetite-related hormones, and perceptual measures of appetite...
April 27, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28444590/transcripts-of-pectin-degrading-enzymes-and-isolation-of-complete-cdna-sequence-of-a-pectate-lyase-gene-induced-by-coffee-white-stem-borer-xylotrechus-quadripes-in-the-bark-tissue-of-coffea-canephora-robusta-coffee
#3
Kosaraju Bharathi, P Santosh, H L Sreenath
Of the two commercially cultivated coffee (Coffea) species, C. arabica (arabica) is highly susceptible and C. canephora (robusta) is highly resistant to the insect pest Xylotrechus quadripes (Coleoptera: Cerambycidae), commonly known as coffee white stem borer (CWSB). We constructed a forward-subtracted cDNA library by Suppression Subtractive Hybridization (SSH) from robusta bark tissue for profiling genes induced by CWSB infestation. Among the 265 unigenes of the SSH EST library, 7 unigenes (5 contigs and 2 singletons) matching different pectin-degrading enzymes were discovered...
May 2017: 3 Biotech
https://www.readbyqxmd.com/read/28443667/identification-of-a-phosphodiesterase-inhibiting-fraction-from-roasted-coffee-coffea-arabica-through-activity-guided-fractionation
#4
Teresa Röhrig, David Liesenfeld, Elke Richling
Recent reports that coffee can significantly inhibit cAMP phosphodiesterases (PDE) in vitro, as well as in vivo, have added another beneficial effect of coffee consumption. However, the PDE-inhibiting substances remain mostly unknown. We chose activity-guided fractionation and an in vitro test system to identify the coffee components responsible for PDE inhibition. This approach indicated that a fraction of melanoidins reveals strong PDE inhibiting potential (IC50 = 130 ± 42 µg/mL). These melanoidins were characterized as water soluble, low molecular weight melanoidins (< 3kDa) with a nitrogen content of 4...
April 26, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28438035/dual-burden-of-malnutrition-among-adolescents-of-smallholder-coffee-farming-households-of-jimma-zone-southwest-ethiopia
#5
Kalkidan Hassen, Getu Gizaw, Tefera Belachew
BACKGROUND: Substantial evidence is emerging on the coexistence of double burden of malnutrition on adolescents of low-income countries, shaping the health challenges of upcoming adult generation for the worst. Whether nutritional status markers of adolescents in the cash crop setting are at par with economic gains remain uncertain so far. Thus, we investigated the nutritional outcomes of adolescents and its determinants in coffee farming households. METHODS: The survey was carried out in 3 top coffee-producing districts of Jimma Zone, Ethiopia...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28437428/prevalence-of-alcohol-use-disorders-among-under-and-post-graduate-healthcare-students-in-italy
#6
Monica Lamberti, Francesco Napolitano, Paola Napolitano, Antonio Arnese, Vincenzo Crispino, Gianclaudio Panariello, Gabriella Di Giuseppe
A cross-sectional study was carried out on 641 medical students, 359 students attending a degree course in the healthcare professions, and 500 resident physicians, all undergoing health surveillance at the ambulatory of the Division of Occupational Medicine, Second University of Naples, Italy. 76.1% of the participants drank alcohol, with 85.5% of medical students, 77.4% of resident physicians, and 63% of healthcare-professions students reporting regular alcohol use. In the whole sample, the mean Audit-C score was 1...
2017: PloS One
https://www.readbyqxmd.com/read/28436066/reduction-by-coffee-consumption-of-prostate-cancer-risk-evidence-from-the-moli-sani-cohort-and-cellular-models
#7
George Pounis, Claudio Tabolacci, Simona Costanzo, Martina Cordella, Marialaura Bonaccio, Livia Rago, Daniela D'Arcangelo, Augusto Filippo Di Castelnuovo, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Francesco Facchiano
Meta-analytic data on the effect of coffee in prostate cancer risk are controversial. Caffeine as a bioactive compound of coffee has not yet been studied in deep in vitro. Our study aimed at evaluating in a population cohort the effect of Italian-style coffee consumption on prostate cancer risk and at investigating in vitro the potential antiproliferative and antimetastatic activity of caffeine on prostate cancer cell lines. 6,989 men of the Moli-sani cohort aged ≥50 years were followed for a mean of 4.24 ± 1...
April 24, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28429922/effect-modification-of-green-tea-on-the-association-between-rice-intake-and-the-risk-of-diabetes-mellitus-a-prospective-study-in-japanese-men-and-women
#8
Akie Hirata, Keizo Ohnaka, Naotaka Tashiro, Zhenjie Wang, Michiko Kohno, Chikako Kiyohara, Suminori Kono, Ryoichi Takayanagi
BACKGROUND AND OBJECTIVES: Recent observational studies have suggested a positive association of white rice and protective associations of green tea and coffee with the risk of diabetes. However, none have examined the interaction between these dietary factors on the risk of diabetes. We prospectively investigated the effect modification of green tea and coffee on the association between rice and incident diabetes in elderly Japanese men and women. METHODS AND STUDY DESIGN: Among subjects who participated in the baseline survey (2004-2007), 11717 (91 %) subjects responded to the follow-up survey (2010-2012)...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28428669/risk-factors-for-osteoporosis-in-postmenopausal-women
#9
Radojka Bijelic, Snjezana Milicevic, Jagoda Balaban
INTRODUCTION: Scientific studies show that many factors related to lifestyles affect the reduction of bone mineral density and osteoporosis in postmenopausal women. GOAL: The goal of this study was to determine whether smoking, drinking coffee and alcohol in menopausal women contribute to the reduction of bone mass and osteoporosis, as well as the impact of physical activity on bone mass. MATERIAL AND METHODS: The study was carried out as case study and matched controls...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28425092/coffee-consumption-and-the-risk-of-colorectal-cancer-by-anatomical-subsite-in-japan-results-from-the-herpacc-studies
#10
Hiroko Senda Nakagawa, Hidemi Ito, Satoyo Hosono, Isao Oze, Hideo Tanaka, Keitaro Matsuo
Consumption of coffee, a popular beverage worldwide, has been associated with lower colorectal cancer (CRC) risk. Although CRC exhibits different biological characteristics by anatomical subsite, the possibly heterogeneous impact of coffee on CRC by anatomical subsite has remained unclear. Here, we conducted two case-control studies to examine the association between coffee consumption and CRC risk as well as risk by anatomic subsite among Japanese using data from the Hospital-based Epidemiological Research Program at Aichi Cancer Center I and II (HERPACC-I and II)...
April 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28424867/j-shaped-relationship-between-habitual-coffee-consumption-and-10-year-2002-2012-cardiovascular-disease-incidence-the-attica-study
#11
Georgia-Maria Kouli, Demosthenes B Panagiotakos, Ekavi N Georgousopoulou, Duane D Mellor, Christina Chrysohoou, Adela Zana, Constantine Tsigos, Dimitrios Tousoulis, Christodoulos Stefanadis, Christos Pitsavos
PURPOSE: The purpose of this work was to evaluate the association between coffee consumption and 10-year cardiovascular disease (CVD) incidence in the ATTICA study, and whether this is modified by the presence or absence of metabolic syndrome (MetS) at baseline. METHODS: During 2001-2002, 3042 healthy adults (1514 men and 1528 women) living in the greater area of Athens were voluntarily recruited to the ATTICA study. In 2011-2012, the 10-year follow-up was performed in 2583 participants (15% of the participants were lost to follow-up)...
April 19, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28422343/e-maldi-optimized-conditions-during-electrowetting-enhanced-drop-drying-for-maldi-ms
#12
Olena Kudina, Huseyin Burak Eral, Frieder Mugele
We recently showed that electrowetting-enhanced sample preparation for MALDI-MS (eMALDI) can increase the intensity of the MALDI signal by 2-25 times compared to conventional drop drying by concentrating all the dried sample in a single spot rather than leaving behind a heterogeneous coffee stain pattern. Here, we demonstrate that the eMALDI signal enhancement can be further increased to more than 100x by systematically optimizing the electrowetting actuation frequency and amplitude. This enables 30x signal increase for a peptide standard...
April 18, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28420078/natural-phenol-polymers-recent-advances-in-food-and-health-applications
#13
REVIEW
Lucia Panzella, Alessandra Napolitano
Natural phenol polymers are widely represented in nature and include a variety of classes including tannins and lignins as the most prominent. Largely consumed foods are rich sources of phenol polymers, notably black foods traditionally used in East Asia, but other non-edible, easily accessible sources, e.g., seaweeds and wood, have been considered with increasing interest together with waste materials from agro-based industries, primarily grape pomace and other byproducts of fruit and coffee processing. Not in all cases were the main structural components of these materials identified because of their highly heterogeneous nature...
April 14, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28414633/genome-wide-analysis-provides-evidence-on-the-genetic-relatedness-of-the-emergent-xylella-fastidiosa-genotype-in-italy-to-isolates-from-central-america
#14
Annalisa Giampetruzzi, Maria Saponari, Giuliana Loconsole, Donato Boscia, Vito Nicola Savino, Rodrigo Almeida, Stefania Zicca, Blanca Landa, Carlos Chacon Diaz, Pasquale Saldarelli
Xylella fastidiosa is a plant pathogenic bacterium recently introduced in Europe that is causing decline in olive trees in the South of Italy. Genetic studies have consistently shown that the bacterial genotype recovered from infected olive trees belongs to the sequence type ST53 within subspecies pauca. This genotype, ST53, has also been reported to occur in Costa Rica. The ancestry of ST53 was recently clarified, showing it contains alleles which are monophyletic with those of subsp. pauca in South America...
April 17, 2017: Phytopathology
https://www.readbyqxmd.com/read/28412986/effects-of-subacute-ingestion-of-chlorogenic-acids-on-sleep-architecture-and-energy-metabolism-through-activity-of-the-autonomic-nervous-system-a-randomised-placebo-controlled-double-blinded-cross-over-trial
#15
Insung Park, Ryuji Ochiai, Hitomi Ogata, Momoko Kayaba, Sayaka Hari, Masanobu Hibi, Yoshihisa Katsuragi, Makoto Satoh, Kumpei Tokuyama
Chlorogenic acids (CGA) are the most abundant polyphenols in coffee. Continuous consumption of CGA reduces body fat and body weight. Since energy metabolism and sleep are controlled by common regulatory factors, consumption of CGA might modulate sleep. Lack of sleep has been identified as a risk factor for obesity, hypertension and type 2 diabetes. The aim of this study was to determine the effects of ingesting CGA over 5 d on energy metabolism and sleep quality in humans. A total of nine healthy subjects (four male and five female) completed a placebo-controlled, double-blinded, cross-over intervention study...
April 17, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28411491/production-of-bio-sugar-and-bioethanol-from-coffee-residue-cr-by-acid-chlorite-pretreatment
#16
Ho Myeong Kim, Yong-Soo Choi, Dae-Seok Lee, Yong-Hwan Kim, Hyeun-Jong Bae
Nowadays, coffee residue (CR) after roasting is recognized as one of the most useful resources in the world for producing the biofuel and bio-materials. In this study, we evaluated the potential of bio-sugar and bioethanol production from acid-chlorite treated CR. Notably, CR treated three times with acid-chlorite after organic solvent extraction (OSE-3), showed the high monosaccharide content, and the efficient sugar conversion yield compared to the other pretreatment conditions. The OSE-3 (6% substrate loading, w/v) can produce bio-sugar (0...
March 28, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28410962/determinaical-disease-synthesis-of-systematic-reviews
#17
Daniel Krewski, Caroline Barakat-Haddad, Jennifer Donnan, Rosemary Martino, Tamara Pringsheim, Helen Tremlett, Pascal van Lieshout, Stephanie J Walsh, Nicholas J Birkett, James Gomes, Julian Little, Sonya Bowen, Hamilton Candundo, Ting-Kuang Chao, Kayla Collins, James A G Crispo, Tom Duggan, Reem El Sherif, Nawal Farhat, Yannick Fortin, Janet Gaskin, Pallavi Gupta, Mona Hersi, Jing Hu, Brittany Irvine, Shayesteh Jahanfar, Don MacDonald, Kyla McKay, Andrea Morrissey, Pauline Quach, Ruksana Rashid, Sabina Shin, Lindsey Sikora, Stacey Tkachuk, Mohamed K Taher, Ming-Dong Wang, Shalu Darshan, Neil R Cashman
Systematic reviews were conducted to identify risk factors associated with the onset and progression of 14 neurological conditions, prioritized as a component of the National Population Health Study of Neurological Conditions. These systematic reviews provided a basis for evaluating the weight of evidence of evidence for risk factors for the onset and progression of the 14 individual neurological conditions considered. A number of risk factors associated with an increased risk of onset for more than one condition, including exposure to pesticides (associated with an increased risk of AD, amyotrophic lateral sclerosis, brain tumours, and PD; smoking (AD, MS); and infection (MS, Tourette syndrome)...
April 11, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28407187/genetic-variability-and-expression-of-agro-morphological-traits-among-genotypes-of-coffea-arabica-being-promoted-by-supplementary-irrigation
#18
W N Rodrigues, S V B Brinate, L D Martins, T V Colodetti, M A Tomaz
The use of supplementary irrigation to sustain the plantation during moments of severe water stress or moments of high water demand is becoming almost a norm to keep sustainable crops, especially due to the climate changes and the high frequency in which climate extremes are occurring lately. The objective of this study was to evaluate the agronomic performance and expression of genetic variability among genotypes of Coffea arabica L. cultivated in farming systems with different levels of water supply, focusing on rainfed or supplementary irrigated systems...
April 13, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28407090/foods-and-beverages-and-colorectal-cancer-risk-a-systematic-review-and-meta-analysis-of-cohort-studies-an-update-of-the-evidence-of-the-wcrf-aicr-continuous-update-project
#19
A R Vieira, L Abar, Dsm Chan, S Vingeliene, E Polemiti, C Stevens, D Greenwood, T Norat
Objective: As part of the World Cancer Research Fund International Continuous Update Project, we updated the systematic review and meta-analysis of prospective studies to quantify the dose-response between foods and beverages intake and colorectal cancer risk. Data Sources: PubMed and several databases up to May 31 st 2015. Study selection: Prospective studies reporting adjusted relative risk estimates for the association of specific food groups and beverages and risk of colorectal, colon and rectal cancer...
April 12, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28405283/anolis-lizards-as-biocontrol-agents-in-mainland-and-island-agroecosystems
#20
Ivan V Monagan, Jonathan R Morris, Alison R Davis Rabosky, Ivette Perfecto, John Vandermeer
Our knowledge of ecological interactions that bolster ecosystem function and productivity has broad applications to the management of agricultural systems. Studies suggest that the presence of generalist predators in agricultural landscapes leads to a decrease in the abundance of herbivorous pests, but our understanding of how these interactions vary across taxa and along gradients of management intensity and eco-geographic space remains incomplete. In this study, we assessed the functional response and biocontrol potential of a highly ubiquitous insectivore (lizards in the genus Anolis) on the world's most important coffee pest, the coffee berry borer (Hypothalemus hampei)...
April 2017: Ecology and Evolution
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