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Mochammad Amrun Hidayat, Nindya Puspitaningtyas, Agus Abdul Gani, Bambang Kuswandi
This work was aimed to develop a chemical sensor for the determination of total polyphenol content (TPC) of coffee samples. The polyphenol sensor was based on co-immobilization of NaIO4 and MBTH in paper as a test strip. The sensor showed sensitive response to chlorogenic acid by forming pink color adduct which can be scanned and quantified by Imagej program. The sensor had response time of 14 min and a linear range between 0.07 and 0.71 mM of chlorogenic acid with a detection limit at 0.002 mM toward chlorogenic acid...
October 2017: Journal of Food Science and Technology
Alex O Okaru, Dirk W Lachenmeier
For decades, compounds present in foods and beverages have been implicated in the etiology of human cancers. The World Health Organization (WHO) International Agency for Research on Cancer (IARC) continues to classify such agents regarding their potential carcinogenicity in humans based on new evidence from animal and human studies. Furfuryl alcohol and β-myrcene are potential human carcinogens due to be evaluated. The major source of furfuryl alcohol in foods is thermal processing and ageing of alcoholic beverages, while β-myrcene occurs naturally as a constituent of the essential oils of plants such as hops, lemongrass, and derived products...
March 11, 2017: Toxics
Jiaqi Huang, Stephanie J Weinstein, Cari M Kitahara, Edward D Karoly, Joshua N Sampson, Demetrius Albanes
Malignant glioma is one of the most lethal adult cancers, yet its etiology remains largely unknown. We conducted a prospective serum metabolomic analysis of glioma based on 64 cases and 64 matched controls selected from Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study. Median time from collection of baseline fasting serum to diagnosis was nine years (inter-decile range 3-20 years). LC/MS-MS identified 730 known metabolites, and conditional logistic regression models estimated odds ratios for one-standard deviation differences in log-metabolite signals...
September 19, 2017: Oncotarget
Bing Cheng, Agnelo Furtado, Robert J Henry
Background: Polyploidization contributes to the complexity of gene expression resulting in numerous related but different transcripts. This study explored the transcriptome diversity and complexity of tetraploid Arabica coffee ( Coffea arabica ) bean. Long-read sequencing (LRS) by Pacbio Isoform sequencing (Iso-seq) was used to obtain full-length transcripts without the difficulty and uncertainty of assembly required for reads from short read technologies. The tetraploid transcriptome was annotated and compared with data from the sub-genome progenitors...
August 30, 2017: GigaScience
Marilyn C Cornelis, Stefan Gustafsson, Johan Ärnlöv, Sölve Elmståhl, Stefan Söderberg, Johan Sundström, Karl Michaëlsson, Lars Lind, Erik Ingelsson
BACKGROUND: Coffee drinking has been implicated in mortality and a variety of diseases but potential mechanisms underlying these associations are unclear. Large-scale systems epidemiological approaches may offer novel insights to mechanisms underlying associations of coffee with health. OBJECTIVE: We performed an analysis of known and novel protein markers linked to cardiovascular disease and their association with habitual coffee intake in the Prospective Study of the Vasculature in Uppsala Seniors (PIVUS, n=816) and followed-up top proteins in the Uppsala Longitudinal Study of Adult Men (ULSAM, n=635) and EpiHealth (n=2418)...
October 16, 2017: Journal of Internal Medicine
Adrian Gütlein, Friederike Gerschlauer, Imani Kikoti, Ralf Kiese
In this study, we quantify the impacts of climate and land use on soil N2 O and CH4 fluxes from tropical forest, agroforest, arable and savanna ecosystems in Africa. To do so, we measured GHG fluxes from twelve different ecosystems along climate and land-use gradients at Mt. Kilimanjaro, combining long-term in situ chamber and laboratory soil-core incubation techniques. Both methods showed similar patterns of GHG exchange. Although there were distinct differences from ecosystem to ecosystem, soils generally functioned as net sources and sinks for N2 O and CH4 , respectively...
October 17, 2017: Global Change Biology
Shuai Yang, Xiao-Fang Zhang, Yu-Lin Gao, Dan Chen, Dong-Mei She, Tao Zhang, Jun Ning
The coffee bean weevil (CBW), Araecerus fasciculatus (De Geer, 1775), is a cosmopolitan stored-product pest, especially in tropical and subtropical areas. Previous reports showed evidence for aggregation behavior of CBW and this study aimed to identify and evaluate the aggregation pheromone of this pest. Whole-body solvent extractions were analyzed by coupled gas chromatography-mass spectrometry and comparison of male and female extracts showed a male-specific compound which was identified as squalene, 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene...
October 17, 2017: Journal of Chemical Ecology
David Samuel Johnson, Bethany L Williams
Specialist species are more vulnerable to environmental change than generalist species. For species with ontogenetic niche shifts, specialization may occur at a particular life stage making those stages more susceptible to environmental change. In the salt marshes in the northeast U.S., accelerated sea level rise is shifting vegetation patterns from flood-intolerant species such as Spartina patens to the flood-tolerant Spartina alterniflora. We tested the potential impact of this change on the coffee bean snail, Melampus bidentatus, a numerically dominant benthic invertebrate with an ontogenetic niche shift...
October 2017: Ecology and Evolution
Gaiqing Kong, Zhihao Zhou, Qining Wang, Konrad Kording, Kunlin Wei
It has been proposed that learning from movement errors involves a credit assignment problem: did I misestimate properties of the object or those of my body? For example, an overestimate of arm strength and an underestimate of the weight of a coffee cup can both lead to coffee spills. Though previous studies have found signs of simultaneous learning of the object and of the body during object manipulation, there is little behavioral evidence about their quantitative relation. Here we employed a novel weight-transportation task, in which participants lift the first cup filled with liquid while assessing their learning from errors...
October 17, 2017: Scientific Reports
Claudia Oellig, Jessica Radovanovic
16-O-Methylcafestol (16-OMC), the characteristic diterpene exclusively present in Coffea canephora, is an excellent marker for Coffea canephora admixtures to Coffea arabica. Here we show a straightforward, selective and sensitive screening method for the determination of 16-OMC in roasted coffee by high-performance thin-layer chromatography with fluorescence detection (HPTLC-FLD). As internal standard, Sudan IV was used, and a direct saponification with 10% ethanolic potassium hydroxide solution was followed by solid supported liquid extraction with petroleum ether...
October 12, 2017: Journal of Chromatography. A
Marta Guasch-Ferré, Shilpa N Bhupathiraju, Frank B Hu
BACKGROUND: Nutritional metabolomics is rapidly evolving to integrate nutrition with complex metabolomics data to discover new biomarkers of nutritional exposure and status. CONTENT: The purpose of this review is to provide a broad overview of the measurement techniques, study designs, and statistical approaches used in nutrition metabolomics, as well as to describe the current knowledge from epidemiologic studies identifying metabolite profiles associated with the intake of individual nutrients, foods, and dietary patterns...
October 16, 2017: Clinical Chemistry
Sónia S Ferreira, Cláudia P Passos, Márcio R Cepeda, Guido R Lopes, Maria Teixeira-Coelho, Pedro Madureira, Fernando M Nunes, Manuel Vilanova, Manuel A Coimbra
An instant coffee fraction, rich in arabinogalactans, obtained by ultrafiltration, using 1 and 5kDa membranes, has previously shown in vitro stimulatory activity on BALB/c mice spleen B lymphocytes. The compounds inducing lymphocytic activation were shown to elute, mainly near the void volume by size-exclusion chromatography, using Bio-Gel P6 (1-6kDa). Treatment of the compounds with chymotrypsin, a digestive protease, did not affect the induced B lymphocyte activation. On the contrary, hydrolysis with an α-l-arabinofuranosidase, removing single terminally-linked arabinose residues, decreased the extent of B cell activation...
March 1, 2018: Food Chemistry
Antonio Augusto Ferreira Carioca, Bartira Gorgulho, Juliana Araujo Teixeira, Regina Mara Fisberg, Dirce Maria Marchioni
OBJECTIVE: The objective of this study was to assess the differences and similarities in dietary patterns among migrants and natives. METHODS: A population-based, cross-sectional study was conducted in the city of São Paulo. The study population included internal migrants, defined as individuals born outside São Paulo city who had lived in the city for ten years or longer. The final population (n = 999) was divided into three groups: natives of São Paulo (n = 354), migrants from the Southeast (n = 349) and migrants from the Northeast (n = 296)...
2017: PloS One
David C Nieman, Courtney L Goodman, Christopher R Capps, Zack L Shue, Robert Arnot
This study measured the influence of 2-weeks ingestion of high chlorogenic acid (CQA) coffee on post-exercise inflammation and oxidative stress, with secondary outcomes including performance and mood state. Cyclists (N=15) were randomized to CQA coffee or placebo (300 ml/day) for 2 weeks, participated in a 50-km cycling time trial, and then crossed over to the opposite condition with a 2-week washout period. Blood samples were collected pre- and post-supplementation, and immediately post-exercise. CQA coffee was prepared using the Turkish method with 30 g lightly roasted, highly ground Hambela coffee beans in 300 ml boiling water, and provided 1,066 mg CQA and 474 mg caffeine versus 187 mg CQA and 33 mg caffeine for placebo...
October 16, 2017: International Journal of Sport Nutrition and Exercise Metabolism
Estela Abich, Daniel Glotzer, Edward Murphy
Gallstone ileus is a rare disease that accounts for 1-4% of intestinal obstructions. Almost exclusively a condition in the older female population, it is a difficult diagnosis to make. We report the case of gallstone ileus in a 94-year-old Caucasian female, who presented to the emergency department with acute-onset nausea, coffee-ground emesis, lack of bowel movement, and abdominal distension. On CT scan, the diagnosis of gallstone ileus was made by the presence of a cholecystoduodenal fistula, pneumobilia, and small bowel obstruction...
May 2017: Case Reports in Gastroenterology
Aneta Buntić, Marija Pavlović, Dušan Antonović, Vladimir Pavlović, Dragana Vrućinić, Slavica Šiler-Marinković, Suzana Dimitrijević-Branković
This study has explored the possibility to reuse the waste, spent coffee material for the cellulase enzyme immobilization. By the coffee surface modification with different activating agents, it was attempted to develop the convenient method for creation of a capable porous carrier for this purpose. Among the most common activating agents, glutaraldehyde, chlorine dioxide and hydrogen peroxide provided the most acceptable choice for the coffee surface modification. The changes that occurred on the coffee surface due to agents' treatment exposure were recorded by using of the FTIR spectra and SEM micrographs...
October 12, 2017: International Journal of Biological Macromolecules
Luis F Aristizábal, Suzanne Shriner, Robert Hollingsworth, Steven Arthurs
The coffee berry borer (CBB), Hypothenemus hampei Ferrari (Coleoptera: Curculionidae: Scolytinae) is a recent invader to Hawaii. To date, limited information regarding the seasonal phenology of this pest on the islands limits the implementation of integrated control strategies. As part of a coffee farmer training program, we monitored CBB flight activity in 15 coffee plantations (Kona and Kau Districts) over 10 mo with methanol-ethanol (3:1 ratio) baited traps. Concurrently, we quantified CBB infestation and penetration rates inside developing coffee berries through the end of harvest...
September 27, 2017: Journal of Economic Entomology
Denise T A da Veiga, Raísa Bringhenti, Aline A Bolignon, Etiane Tatsh, Rafael N Moresco, Fabio V Comim, Melissa O Premaor
Nutritional factors have been associated with osteoporosis and fractures. The intake of coffee may increase the risk of fracture whereas the intake of black and green tea is associated with its reduction. Recently, consumption of yerba mate was associated with increased bone mineral density in postmenopausal women. Nonetheless, its influence on fracture is not known. The aim of this study was to evaluate the effect of yerba mate tea intake on fractures, bone markers, calcium homeostasis, and oxidative stress in postmenopausal women...
October 13, 2017: Phytotherapy Research: PTR
Salomone Di Saverio, Alice Piccinini, Arianna Birindelli, Carlo Fabbri, Stefano Pretolani
No abstract text is available yet for this article.
October 12, 2017: BMJ: British Medical Journal
Yaping Qian, Debora Mancini-DiNardo, Thaddeus Judkins, Hannah C Cox, Krystal Brown, Maria Elias, Nanda Singh, Courtney Daniels, Jayson Holladay, Bradford Coffee, Karla R Bowles, Benjamin B Roa
Cancer risks have been previously reported for some retrotransposon element (RE) insertions; however, detection of these insertions is technically challenging and very few oncogenic RE insertions have been reported. Here we evaluate RE insertions identified during hereditary cancer genetic testing using a comprehensive testing strategy. Individuals who had single-syndrome or pan-cancer hereditary cancer genetic testing from February 2004 to March 2017 were included. RE insertions were identified using Sanger sequencing, Next Generation Sequencing, or multiplex quantitative PCR, and further characterized using targeted PCR and sequencing analysis...
October 2017: Cancer Genetics
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