Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
REVIEW
Jiaqi Zeng, Xinchan Wang, Fei Pan, Zhiqi Mao
An increasing number of studies have provided evidence for the hypothesis that the pathogenesis of Parkinson's disease (PD) may derive from the gut. Firstly, Lewy pathology can be induced in the enteric nervous system (ENS) and be transported to the central nervous system (CNS) via the vagal nerve. Secondly, the altered composition of gut microbiota causes an imbalance between beneficial and deleterious microbial metabolites which interacts with the increased gut permeability and the gut inflammation as well as the systemic inflammation...
2022: Frontiers in Aging Neuroscience
#22
JOURNAL ARTICLE
Carlos Perez Hernandez, Islam Younes, Sherif Elkattawy, Paul Fanous, Daphne Gonzalez Aponte, Omar Makanay, Arun Naik
UNLABELLED: Diverticulitis and ulcerative colitis (UC) are two separate colonic pathologies with different underlying mechanisms. Diverticulosis involves herniation of mucosal and submucosal tissue through muscular tissue in response to increased intraluminal pressure. In contrast, it is believed that the muscular tone in patients with UC is reduced due to chronic inflammatory changes. Thus, it has been reported that there may be an inverse relationship between the presence of diverticulosis in patients with UC, in that UC may possibly be protective against developing diverticular disease...
2022: European Journal of Case Reports in Internal Medicine
#23
Eugene C Nwankwo, Gebran Khneizer, Gregory Sayuk, Jill Elwing, Necat Havlioglu, Michael Presti
Segmental colitis associated with diverticulosis (SCAD) is an inflammatory disease affecting segments of the large bowel with diverticular disease. SCAD presents several challenges in diagnoses and treatment because it often mimics a range of disorders including inflammatory bowel disease and malignancy. Here, we present the case of a 72-year-old man with lower abdominal pain and bloody stools whose initial abdominal workup showed nonspecific large bowel thickening and concerns for malignancy. Ultimately, the patient was diagnosed with mild SCAD and treated conservatively with a resolution of symptoms...
March 2022: Curēus
#24
JOURNAL ARTICLE
Pedro Valdez-Hernández, Luis Delgado-Soler, Angel Martínez-Munive, Diego Angulo-Molina, Daniel Keil-Ríos
No abstract text is available yet for this article.
November 15, 2021: Gastroenterología y Hepatología
#25
REVIEW
Jason D Eckmann, Aasma Shaukat
PURPOSE OF REVIEW: Diverticulosis leads to significant morbidity and mortality and is increasing in prevalence worldwide. In this paper, we review the clinical features, diagnosis, and management of diverticular disorders, followed by a discussion of recent updates and changes in the clinical approach to diverticular disease. RECENT FINDINGS: Recent literature suggests that antibiotics are likely not necessary for low-risk patients with acute uncomplicated diverticulitis, and not all patients with recurrent diverticulitis require colectomy...
January 1, 2022: Current Opinion in Gastroenterology
#26
JOURNAL ARTICLE
Douglas Chung
INTRODUCTION: The common manifestations of gastrointestinal stromal tumors (GIST) are well established. However, jejunal diverticulosis is an uncommon phenomenon to be associated with this lesion, with its rarity compounded by the relative difficulty associated with its diagnosis. Limited literature is available on this topic. This article examines one such case of jejunal diverticulitis as a result of a GIST, and the intervention of said disease. CASE PRESENTATION: A 69 year old lady presented with abdominal pain, vomiting, and low grade fevers, on a background of ulcerative colitis...
August 8, 2021: International Journal of Surgery Case Reports
#27
MULTICENTER STUDY
Naoyoshi Nagata, Katsumasa Kobayashi, Atsushi Yamauchi, Atsuo Yamada, Jun Omori, Takashi Ikeya, Taiki Aoyama, Naoyuki Tominaga, Yoshinori Sato, Takaaki Kishino, Naoki Ishii, Tsunaki Sawada, Masaki Murata, Akinari Takao, Kazuhiro Mizukami, Ken Kinjo, Shunji Fujimori, Takahiro Uotani, Minoru Fujita, Hiroki Sato, Sho Suzuki, Toshiaki Narasaka, Junnosuke Hayasaka, Tomohiro Funabiki, Yuzuru Kinjo, Akira Mizuki, Shu Kiyotoki, Tatsuya Mikami, Ryosuke Gushima, Hiroyuki Fujii, Yuta Fuyuno, Naohiko Gunji, Yosuke Toya, Kazuyuki Narimatsu, Noriaki Manabe, Koji Nagaike, Tetsu Kinjo, Yorinobu Sumida, Sadahiro Funakoshi, Kana Kawagishi, Tamotsu Matsuhashi, Yuga Komaki, Kuniko Miki, Kazuhiro Watanabe, Masakatsu Fukuzawa, Takao Itoi, Naomi Uemura, Takashi Kawai, Mitsuru Kaise
INTRODUCTION: The bleeding source of hematochezia is unknown without performing colonoscopy. We sought to identify whether colonoscopy is a risk-stratifying tool to identify etiology and predict outcomes and whether presenting symptoms can differentiate the etiologies in patients with hematochezia. METHODS: This multicenter retrospective cohort study conducted at 49 hospitals across Japan analyzed 10,342 patients admitted for outpatient-onset acute hematochezia...
November 1, 2021: American Journal of Gastroenterology
#28
REVIEW
F Vulsteke, G De Hertogh, S Vermeire
BACKGROUND: Diverticular associated colitis (DAC) has become increasingly appreciated as a form of inflammatory disease, localized mainly in the sigmoid, and defined as chronic inflammation of the interdiverticular mucosa with sparing of rectum, right colon and diverticula themselves. METHODS: A retrospective case identification from January 2005 to December 2016 was performed. Patients with a diagnosis of DAC based on clinical, endoscopic and histological findings were enrolled...
2021: Acta Gastro-enterologica Belgica
#29
EDITORIAL
T Vanuytsel, C Reenaers
No abstract text is available yet for this article.
April 2021: Acta Gastro-enterologica Belgica
#30
REVIEW
Vetri Sudar Jayaprakasam, Viktoriya Paroder, Heiko Schöder
In the past two decades, PET/CT has become an essential modality in oncology increasingly used in the management of gastrointestinal (GI) cancers. Most PET/CT tracers used in clinical practice show some degree of GI uptake. This uptake is quite variable and knowledge of common patterns of biodistribution of various radiotracers is helpful in clinical practice. 18 F-Fluoro-Deoxy-Glucose (FDG) is the most commonly used radiotracer and has quite a variable uptake within the bowel. 68 Ga-Prostate specific membrane antigen (PSMA) shows intense uptake within the proximal small bowel loops...
September 2021: Seminars in Nuclear Medicine
#31
REVIEW
Joanna Giang, Xiao Lan, Megan Crichton, Wolfgang Marx, Skye Marshall
AIM: Biophenol-rich nutraceuticals may be an adjuvant treatment for Crohn's disease (CD), ulcerative colitis (UC), symptomatic uncomplicated diverticular disease (SUDD), and irritable bowel syndrome (IBS). This systematic review and meta-analysis aimed to determine the efficacy and safety of biophenol-rich nutraceutical supplementation on CD, UC, SUDD, and IBS on gastrointestinal symptoms (GIS), quality of life (QoL), inflammatory and oxidative stress biomarkers, and adverse events compared to usual care or placebo...
February 2022: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
#32
JOURNAL ARTICLE
Irene Marafini, Silvia Salvatori, Irene Rocchetti, Norma Alfieri, Patrizio Scarozza, Emma Calabrese, Livia Biancone, Giovanni Monteleone
Ulcerative colitis (UC) and colonic diverticulosis can co-exist in some patients. However, the natural history of UC associated with colonic diverticulosis is not well known. We here compared the disease characteristics and outcome of UC patients with and without concomitant colonic diverticulosis. Medical records of 347 UC patients were included in an observational, retrospective, nested-matched case-control study. Cases were 92 patients with UC and concomitant colonic diverticulosis, while controls were 255 UC patients without concomitant colonic diverticulosis...
March 12, 2021: Journal of Clinical Medicine
#33
JOURNAL ARTICLE
Piyumi Sachindra Alwis Wijewickrama, Vithiya Ratnasamy, Noel P Somasundaram, Manilka Sumanatilleke, Sathyajith Buddhika Ambawatte
BACKGROUND: Cushing's syndrome occurs due to overproduction of cortisol from adrenal glands. Endogenous hypercortisolemia can occur secondary to adrenocorticotropic hormone (ACTH) dependent as well as independent causes. The presence of non-specific symptoms and signs contributes to a delay in diagnosis. Early identification and prompt definitive management is crucial. It is important to be alert about the post-operative complications including multiple thrombotic phenomena, which can add to the mortality...
February 23, 2021: BMC Endocrine Disorders
#34
JOURNAL ARTICLE
Asad Ur Rahman, Ishtiaq Hussain, Badar Hasan, Mamoon Ur Rashid, Kanwarpreet Singh Tandon, Fernando Castro
BACKGROUND: There has been a historic similarity in the epidemiology and pathophysiology of diverticular disease and inflammatory bowel disease (IBD). Because there are limited to no data on the role of diverticulitis as a potential risk factor for de novo IBD, we aimed to evaluate the role of diverticulitis and complicated diverticulitis as a potential predictor of IBD. METHODS: We performed a retrospective, single-center study including patients older than age 18 years who were diagnosed with diverticulitis from January 2012 until December 2018 without a prior diagnosis of IBD...
June 15, 2021: Inflammatory Bowel Diseases
#35
REVIEW
David Wan, Tibor Krisko
Diverticulosis is an anatomic change in the colon that is characterized by outpouching of the mucosa and submucosa through the muscularis. Its prevalence increases with age so most of the elderly patients have this condition. Although diverticulosis is common, diverticular disease, in which there are clinical sequelae, is rare. This collective term includes diverticulitis, diverticular hemorrhage and less well-defined entities such as segmental colitis associated with diverticulosis, and symptomatic uncomplicated diverticular disease...
February 2021: Clinics in Geriatric Medicine
#36
REVIEW
Imran Aziz, Magnus Simrén
Irritable bowel syndrome (IBS) is a common functional bowel disorder characterised by symptoms of recurrent abdominal pain associated with a change in bowel habit. This condition is one of the most frequent reasons to seek a gastroenterology consultation in primary and secondary care. The diagnosis of IBS is made by identifying characteristic symptoms, as defined by the Rome criteria, and excluding organic gastrointestinal diseases that might otherwise explain these symptoms. Organic conditions that can be mistaken for IBS include coeliac disease, inflammatory bowel disease (IBD), colorectal cancer, and, in those with diarrhoea-predominant symptoms, chronic gastrointestinal infections, microscopic colitis, and primary bile acid diarrhoea...
February 2021: Lancet. Gastroenterology & Hepatology
#37
JOURNAL ARTICLE
F R Ponziani, F Scaldaferri, M De Siena, F Mangiola, M V Matteo, S Pecere, V Petito, F Paroni Sterbini, L R Lopetuso, L Masucci, G Cammarota, M Sanguinetti, A Gasbarrini
Compositional and functional alterations of the gut microbiota are involved in the pathogenesis of several gastrointestinal diseases. Rifaximin is often used to induce disease remission due to its eubiotic effects on the gut microbiota. To investigate the correlation between changes in the gut microbiota composition and symptoms improvement in patients who present a clinical response to rifaximin treatment. Patients with ulcerative colitis (UC), Crohn's disease (CD), irritable bowel syndrome (IBS) and diverticular disease (DD) undergoing rifaximin treatment for clinical indication were enrolled in the study...
October 12, 2020: Beneficial Microbes
#38
JOURNAL ARTICLE
Roula Katerji, Aaron R Huber
BACKGROUND Inflammatory pseudopolyps (IPPs) are a common manifestation in inflammatory bowel disease (IBD) with more cases reported with ulcerative colitis than Crohn's disease. IPPs can grow to form large polyps which are called giant inflammatory polyps (GIPs). These polyps may cause an obstruction and form a mass-like lesion and surgical resection may be warranted. CASE REPORT A 65-year-old male without a previous history of IBD presented with abdominal discomfort, poor appetite, constipation, weight loss, and hematochezia...
June 29, 2020: American Journal of Case Reports
#39
Lolwa Al-Obaid, Thomas R McCarty, Ahmad Najdat Bazarbashi, Tad J Wieczorek, Erika Rangel, Daria Homenko
Segmental colitis associated with diverticulosis (SCAD) is a rare inflammatory condition affecting segments of the colon with diverticular disease. We present an 85-year-old woman with flank pain, fevers, and chills found on imaging to have left colonic wall thickening and left-sided hydroureteronephrosis and workup confirming a diagnosis of SCAD. A detailed review of SCAD and discussion of the differential diagnosis are provided. This case emphasizes disease-specific clinical pearls and highlights hydroureteronephrosis as a rare complication seen in a patient with SCAD...
November 2019: ACG Case Reports Journal
#40
JOURNAL ARTICLE
Davor Štimac, Gerardo Nardone, Andrea Mazzari, Antonio Crucitti, Giovanni Maconi, Walter Elisei, Alessandra Violi, Antonio Tursi, Francesco Di Mario
In this session different issues for the diagnosis of diverticular disease (DD) were considered including "Biomarkers", "Computer tomography", "Ultrasonography in detecting acute diverticulitis", "Endoscopy" and "The DICA classification: a new predictive tool in managing diverticular disease". Most patients affected by DD suffer from recurrent attacks of abdominal pain without evidence of an active inflammatory process, causing a difficult differential diagnosis with other intestinal conditions. Several biomarkers, serological, fecal, urinary and genetic were considered, but recent studies confirmed that only CRP and fecal calprotectin are matching with the criteria for an ideal biomarker for DD...
December 19, 2019: Journal of Gastrointestinal and Liver Diseases: JGLD
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
