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Small bowel neoplasm

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https://www.readbyqxmd.com/read/28105351/experience-in-clinical-diagnosis-and-treatment-of-duodenal-tumors
#1
Zheng Wang, Zihai Ding, Shijie Huang, Shizhen Zhong
Small bowel tumors are rare tumors. Duodenal tumors occur more commonly compared with other small intestinal tumors. To summarize the clinicopathological features of duodenal tumors, in the present study 44 cases of duodenal tumors were collected, and the comparative clinicopathological characteristics between tumors of the ampulla and non-ampulla, the choice of treatment, and differences in the prognosis, were analyzed. The pathological type identified was predominantly adenocarcinoma; periampullary duodenal tumors were almost classifiable as adenocarcinoma in terms of their type...
December 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28103499/incarcerated-incisional-hernia-of-the-sigmoid-colon-after-appendectomy-a-case-report
#2
Pyong Wha Choi
INTRODUCTION: Incisional hernia after appendectomy is rare, affecting 0.4% to 0.9% of cases. The small bowel and omentum are commonly herniated through the abdominal wall defect, but incisional hernia of the sigmoid colon is extremely rare. CASE PRESENTATION: A 78-year-old man presented with a right lower quadrant abdominal wall mass on the previous McBurney incision site. He had a history of appendectomy for appendicitis 40 years ago. Computed tomography (CT) showed the sigmoid colon herniated thorough the abdominal wall defect...
January 5, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28088602/aggressive-surgical-approach-to-the-management-of-neuroendocrine-tumors-a-report-of-1-000-surgical-cytoreductions-by-a-single-institution
#3
Eugene A Woltering, Brianne A Voros, David T Beyer, Yi-Zarn Wang, Ramcharan Thiagarajan, Pamela Ryan, Anne Wright, Robert A Ramirez, M Jennifer Ricks, J Philip Boudreaux
BACKGROUND: Neuroendocrine tumors (NETs) are rare neoplasms. Our group has treated over 2,000 NET patients and has performed over 1,000 surgical cytoreductive procedures. STUDY DESIGN: Records of 834 NET patients who underwent surgical cytoreduction at our institution were reviewed. Demographic information, intraoperative findings, extent of disease, complications, and survival rates were calculated. RESULTS: 800 patients underwent 1,001 cytoreductive surgeries...
January 11, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28077483/primary-sarcomatoid-carcinoma-of-the-small-intestine-very-rare-and-aggressive-tumour
#4
Peter Abotaga Andrawes, Masood Shariff, Qing Chang, Roman Grinberg
Sarcomatoid carcinoma of the small intestine is a very rare and aggressive variant of small intestinal cancers with poor prognosis. The tumour primarily affects middle-aged and older patients with a mean age of 57 years at the time of presentation. We report a woman aged 58 years without any relevant medical history who presented with small intestinal obstruction. She underwent radiologic and endoscopy investigation with persistent features of small bowel obstruction. The patient was found to have a small bowel tumour causing the obstruction and underwent surgical excision of the tumour...
January 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/27900093/primary-gastrointestinal-stromal-tumour-of-the-ileum-pre-operatively-diagnosed-as-an-abdominal-abscess
#5
Patrizia Rubini, Francesco Tartamella
The present case report described the acute presentation, diagnosis and management of a primary gastrointestinal stromal tumour (GIST) of the ileum. A male patient (age, 51 years) was admitted to Maggiore Hospital (Parma, Italy) due to presenting with fever, dysuria and lower abdominal pain. Ultrasonography and computed tomography showed a 7,5×5,5-cm pelvic mass containing air and purulent fluid indicative of an intraperitoneal abscess. The patient was subjected to diagnostic laparoscopy, which revealed a huge, soft cystic mass arising from the small bowel...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27872539/adenosquamous-carcinoma-of-the-duodenum-a-rare-entity
#6
Garima Daga, Prashant Kerkar
Adenosquamous carcinomas (ASC) of the duodenum are extremely rare neoplasms. They have been reported throughout gastrointestinal tract, including the gastroesophageal junction and the anal canal. Only a few cases of ASC of the small bowel and duodenum have been reported in the literature. Here in we report a case ASC of the second part of the duodenum in a 78-year-old man.
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27783113/small-bowel-neoplasms-enhancement-patterns-and-differentiation-using-post-contrast-multiphasic-multidetector-ct
#7
Takayoshi Shinya, Ryota Inai, Takashi Tanaka, Noriaki Akagi, Shuhei Sato, Tadashi Yoshino, Susumu Kanazawa
PURPOSE: The purpose of the present study was to analyze the enhancement patterns of small bowel neoplasms on post-contrast multiphasic multidetector CT and to assess the diagnostic capacity for differentiating five tumor types. METHODS: We performed a retrospective study of data on 92 small bowel neoplasms. The neoplasms were categorized into five groups according to pathology findings, not imaging findings (23 adenocarcinomas; 22 lymphomas; 19 metastases; 18 gastrointestinal stromal tumors [GIST]; 10 neuroendocrine tumors [NET])...
October 25, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27777768/jak2-v617f-mutation-multiple-hematologic-and-non-hematologic-processes-an-association
#8
Kenneth G Liu, Amit Verma, Olga Derman, Noah Kornblum, Murali Janakiram, Ira Braunschweig, Ramakrishna Battini
BACKGROUND: Population studies showed that patients with JAK2 V617F mutation had increased mortality, and increased risk of any cancer, hematologic cancer, and myeloproliferative disease. CASE PRESENTATION: A 68-year-old Asian male with JAK2 V617F mutation developed four different hematologic and non-hematologic neoplastic processes. In 2009, he was diagnosed with stage IA lung adenocarcinoma and also noted to have worsening leukocytosis and thrombocytosis with peak platelet count of 1,054,000/mL)...
2016: Biomarker Research
https://www.readbyqxmd.com/read/27668116/recurrent-midgut-bleeding-due-to-jejunal-angioleiomyoma
#9
Mahir Gachabayov, Petr Mityushin
Angioleiomyoma being a type of true smooth muscle gastrointestinal tumors can lead to serious life-threatening gastrointestinal bleeding. We report a case of 21-year-old male patient with recurrent midgut bleeding. Contrast-enhanced CT revealed highly vascular small bowel neoplasm. The patient underwent laparotomy with bowel resection and recovered uneventfully. Histopathology revealed jejunal angioleiomyoma.
2016: Case Reports in Surgery
https://www.readbyqxmd.com/read/27528467/localized-high-grade-gastroenteropancreatic-neuroendocrine-tumors-defining-prognostic-and-therapeutic-factors-for-a-disease-of-increasing-clinical-significance
#10
C Mosquera, N J Koutlas, T L Fitzgerald
BACKGROUND: Due to the limited sample size in the existing series, the natural history and management of high-grade gastroenteropancreatic neuroendocrine tumors (GEP-NET) is poorly understood. In order to better understand high-grade GEP-NET, a large cohort study was undertaken. OBJECTIVE: To determine the prognostic factors associated with high-grade GEP-NET. METHODS: Patients diagnosed with non-metastatic high-grade GEP-NET from 1988 to 2010 were identified in SEER...
October 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27212431/digestive-neuroendocrine-neoplasms-a-2016-overview
#11
REVIEW
Elettra Merola, Maria Rinzivillo, Noemi Cicchese, Gabriele Capurso, Francesco Panzuto, Gianfranco Delle Fave
Digestive neuroendocrine neoplasms (DNENs) have an incidence of 2.39 per 100,000 inhabitants per year, and a prevalence of 35 cases per 100,000; the gap between these rates is to be referred to the relatively long survival that characterizes the majority of these tumors, which can be thus considered as chronic oncological diseases. Up to 80% of patients are stage IV since the first diagnosis, presenting a 5-yr overall survival rate of 35%-55% and a twice higher mortality than limited disease. DNENs express somatostatin receptors in more than 80% of cases, detected through immunohistochemistry or functional imaging tests (FITs)...
August 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/27179285/review-of-a-non-epithelial-tumour-of-the-small-bowel-after-c-kit-revolution
#12
Enrico Fiori, Daniele Ferraro, Alessandro De Cesare, Giovanni Leone, Cecilia Barmann, Alberto Schillaci, Francesco Borrini
UNLABELLED: In this article, we reviewed the case of a patient who was object, in 1999, of a published case report of schwannoma of the jejunal wall. Recently, the patient has been referred to our institution for a mass of the stomach identified by upper gastrointestinal endoscopy. The patient underwent a wedge resection of the stomach and a histopathological diagnosis of GIST of the stomach, based on a positive immunohistochemical staining of c-kit and CD34, was made. In consideration of these findings, we performed immunohistochemistry for c-kit and for CD34 on the previous lesion of the jejunal wall, which resulted strongly positive for CD117 and negative for CD34...
2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27161548/a-76-year-old-male-with-an-unusual-presentation-of-merkel-cell-carcinoma
#13
Joel C Acab, Wade Kvatum, Chukwuma Ebo
INTRODUCTION: Merkel Cell Carcinoma is an aggressively malignant, neuroendocrine-derived, cutaneous neoplasm that commonly affects sun-exposed areas of the elderly population. MCC typically presents as a rapidly enlarging, painless nodule that is red to purple in color and located on sun exposed areas such as the head, neck and arms. Although rare, cases of MCC on non-sun exposed skin have been documented and typically have a worse prognosis. PRESENTATION OF CASE: We report an atypical case of Merkel Cell Carcinoma originating in a non-sun exposed area of the body with evidence of distant metastasis...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27157712/inflammatory-fibroid-polyp-of-the-gastrointestinal-tract-10-years-of-experience-at-the-instituto-nacional-de-ciencias-m%C3%A3-dicas-y-nutrici%C3%A3-n-salvador-zubir%C3%A3-n
#14
A F Romano-Munive, R Barreto-Zuñiga, J A Rumoroso-García, P Ramos-Martínez
BACKGROUND: Inflammatory fibroid polyp (lFP) is a rare, benign, and solitary neoplasm predominantly located in the gastric antrum and small bowel. Its clinical symptoms are heterogeneous and essentially depend on the location and size of the tumor. Definitive diagnosis is made through histopathology and this pathology has excellent long-term prognosis. AIM: To identify the cases of IFP seen at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán over a 10-year period...
July 2016: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/27156864/long-term-efficacy-of-90-y-dotatate-in-patients-with-nonresectable-pancreatic-and-small-bowel-neuroendocrine-neoplasms
#15
Wojciech Rogowski, Ewa Wachuła, Anna Lewczuk, John R Buscombe, Nina Seklecka, Artur Sankowski, Jarosław B Ćwikła
AIM: To determine the efficacy of (90)Y [DOTA(0), D-Phe(1), Tyr(3)]-octreotate (DOTATATE) in 67 patients with pancreatic and small bowel neuroendocrine tumors (NETs). PATIENTS & METHODS: The primary efficacy end point was overall survival (OS) and secondary end points were progression-free survival (PFS) and tumor response. RESULTS: Median PFS in pancreatic and small bowel NETs was 25 and 28 months, respectively, and median OS was 42 and 38...
August 2016: Future Oncology
https://www.readbyqxmd.com/read/27134931/ileo-ileal-intussusception-and-bowel-obstruction-caused-by-plasmablastic-lymphoma-of-small-bowel-a-rare-entity-in-rare-location
#16
Aditya Atul Kulkarni, Sanjiv S Thakur
Intussusception of small bowel is considered a rare cause of bowel obstruction in adults accounting for only about 1% of bowel obstruction in adults. Intussusception in adults is uncommon with 95% cases of intussusceptions occurring in children. Adult intussusception from small intestinal lymphoma is also rare with only 36 cases reported in the literature between 2000 and 2011. Plasmablastic lymphoma (PBL) is an aggressive lymphoid neoplasm usually seen in the oral cavity in the clinical setting of human immunodeficiency virus (HIV) infection...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27124967/-management-of-treatment-in-patients-with-neuroendocrine-neoplasmas-of-digestive-tract
#17
Sona Kinová, Martina Kovácová, Martin Caprnda, Michal Koren
Neuroendocrine neoplasmas are a form of cancer arising from cells of diffuse neuroendocrine system. They produce peptides or amines that act as hormones or neurotransmitters. Incidence of NENs is relatively low. Diagnostic work-up and treatment requires a multidisciplinary team approach. The aim of this study was an analysis of data from patients with well-differentiated neuroendocrine neoplasmas of gastrointestinal tract. The study included patients followed up from 1998 to 2013 with histologically confirmed well-differentiated digestive neuroendocrine neoplasm with low or intermediate malignant potential...
December 2015: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27104828/dna-methylation-and-mutation-of-small-colonic-neoplasms-in-ulcerative-colitis-and-crohn-s-colitis-implications-for-surveillance
#18
David H Johnson, William R Taylor, Mohammed M Aboelsoud, Patrick H Foote, Tracy C Yab, Xiaoming Cao, Thomas C Smyrk, Edward V Loftus, Douglas W Mahoney, David A Ahlquist, John B Kisiel
BACKGROUND: Stool DNA testing in patients with inflammatory bowel disease (IBD) may detect colorectal cancer and advanced precancers with high sensitivity; less is known about the presence of DNA markers in small IBD lesions, their association with metachronous neoplasia, or contribution to stool test positivity. METHODS: At a single center in 2 blinded phases, we assayed methylated bone morphogenic protein 3, methylated N-Myc downstream-regulated gene 4, and mutant KRAS in DNA extracted from paraffin-embedded benign lesions, and matched control tissues of patients with IBD, who were followed for subsequent colorectal dysplasia...
July 2016: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/27094797/inflammatory-myofibroblastic-tumor-of-the-small-intestine-mimicking-acute-appendicitis-a-case-report-and-review-of-the-literature
#19
REVIEW
Alexandra Oeconomopoulou, Yvelise de Verney, Katerina Kanavaki, Kalliopi Stefanaki, Kitty Pavlakis, Christos Salakos
BACKGROUND: Inflammatory myofibroblastic tumor is a rare tumor of a borderline malignancy. Although it is commonly seen in children, the number of childhood cases in the current literature is limited. The lung is the most commonly affected location. However, cases that have been documented in the mesentery-omentum have mostly been located in the mesentery of the small bowel and not in the antimesenteric edge as in our patient. CASE PRESENTATION: A 6-year-old Greek boy was referred to our hospital with acute abdominal pain mimicking appendicitis...
April 19, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27086004/small-bowel-neoplasms-and-polyps
#20
REVIEW
Kamron Pourmand, Steven H Itzkowitz
The small intestine is a relatively privileged organ that only rarely develops malignant or even benign tumors. Given this rarity, the relative inaccessibility of the organ during routine endoscopic procedures, and the typical absence or nonspecific nature of clinical manifestations, these tumors often go undiagnosed. Treatment and prognosis are tailored to each histological subtype of tumor. This chapter will discuss the epidemiology, presentation, diagnostics, and management for the most common small bowel tumors, and will highlight the importance of recognizing patients at higher risk of small bowel neoplasia...
May 2016: Current Gastroenterology Reports
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