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Allergic proctocolitis

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https://www.readbyqxmd.com/read/27706457/allergic-proctocolitis-in-infants-analysis-of-the-evolution-of-the-nutritional-status
#1
Ludmilla S Camargo, Jonas Ac Silveira, José Aac Taddei, Ulysses Fagundes
Background: Allergic proctocolitis is a disease that affects infants in the first months. The change in feed is the primary factor for clinical improvement and maintenance of the nutritional status of the infant. Objective: Study the anthropometric evolution of infants with allergic proctocolitis at diagnosis and 1 to 6 months after nutritional intervention. Methods: A retrospective cohort of infants with allergic proctocolitis diagnosis followed at the Pediatric Gastroenterology Institute of São Paulo (IGASTROPED), Brazil...
October 2016: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/27637372/non-ige-mediated-gastrointestinal-food-allergies-in-children
#2
Jean-Christoph Caubet, Hania Szajewska, Raanan Shamir, Anna Nowak-Węgrzyn
Non-IgE-mediated gastrointestinal food allergic disorders (non-IgE-GI-FA) including food protein-induced enterocolitis syndrome (FPIES), food protein-induced enteropathy (FPE) and food protein-induced allergic proctocolitis (FPIAP) are relatively uncommon in infants and young children, but are likely under-diagnosed. Non-IgE-GI-FA have a favorable prognosis, with majority resolving by age 3-5 years. Diagnosis relies on the recognition of symptoms pattern in FPIAP and FPIES and biopsy in FPE. Further studies are needed for a better understanding of the pathomechanism, which will lead eventually to the development of diagnostic tests and treatments...
September 17, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/27568925/presumed-allergic-proctocolitis-resolves-with-probiotic-monotherapy-a-report-of-4-cases
#3
Victoria J Martin, Wayne G Shreffler, Qian Yuan
BACKGROUND The prevalence of allergic diseases has been dramatically rising in the United States and other developed nations over recent decades. Growing evidence suggests a partial role for the microbiome in the development of these allergic diseases. Food protein-induced allergic proctocolitis (AP) (also referred to as cow's milk protein intolerance or allergy) is among the earliest and most common food allergic diseases of infancy, yet its pathophysiology is not well understood. The currently accepted clinical practice is to restrict the diet until 12 months of age...
2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27498217/awareness-of-allergic-enterocolitis-among-primary-care-paediatricians-a-web-based-pilot-survey
#4
P Comberiati, M Landi, A Martelli, G L Piacentini, C Capristo, G Paiola, D G Peroni
BACKGROUND: Allergic enterocolitis, also known as food protein-induced enterocolitis syndrome (FPIES), is an increasingly reported and potentially severe non-IgE mediated food allergy of the first years of life, which is often misdiagnosed due to its non-specific presenting symptoms and lack of diagnostic guidelines. OBJECTIVE: We sought to determine the knowledge of clinical, diagnostic and therapeutic features of FPIES among Italian primary-care paediatricians...
September 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/26588792/food-protein-induced-non-immunoglobulin-e-mediated-allergic-colitis-in-infants-and-older-children-what-cytokines-are-involved
#5
Ahmet Ozen, Enver Mahir Gulcan, Hulya Ercan Saricoban, Ferda Ozkan, Reha Cengizlier
BACKGROUND: Food protein-induced allergic proctocolitis (FPIAP) is mostly a non-immunoglobulin E-mediated disease where a T-cell-mediated reaction to cow's milk protein has been suggested. We determined the expression of transforming growth factor (TGF)-β, TGF-β receptor-1, tumor necrosis factor (TNF)-α, CD86, and CD23 on the colon mucosa to investigate their roles in the pathogenesis of the two subtypes of FPIAP, i.e. infantile FPIAP and FPIAP in older children. METHODS: Group 1 comprised children with infantile FPIAP (age <6 months, n = 21), group 2 referred to FPIAP in older children (age >1...
2015: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/26465798/authors-response
#6
LETTER
Aysenur Kaya, Ersoy Civelek, Can Naci Kocabas
No abstract text is available yet for this article.
January 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26418209/distal-proctocolitis-in-infants-is-it-always-an-allergic-disease
#7
LETTER
K Martin Hoffmann, Laura Stampfer, Almuth C Hauer
No abstract text is available yet for this article.
January 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26182504/-cow-s-milk-challenges-in-gastrointestinal-cow-s-milk-allergic-diseases
#8
Tang Lujing, Zhao Hong, Chen Jie
OBJECTIVE: To understand the clinical features of gastrointestinal cow's milk allergy in children, and to assess the importance of cow's milk challenge. METHOD: An analysis was performed on the clinical manifestations and the challenge results of 50 children who received cow's milk challenges after admission to the department of gastroenterology, Children' s Hospital of Zhejiang University School of Medicine from January,2009 to December, 2012. The value of immunoglobulin E antibody was also analyzed among the 50 children, 25 cases were male and the other 25 were female...
April 2015: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/26174434/food-protein-induced-enterocolitis-syndrome-allergic-proctocolitis-and-enteropathy
#9
REVIEW
Elizabeth Feuille, Anna Nowak-Węgrzyn
Food protein-induced enterocolitis (FPIES), allergic proctocolitis (FPIAP), and enteropathy (FPE) are among a number of immune-mediated reactions to food that are thought to occur primarily via non-IgE-mediated pathways. All three are typically present in infancy and are triggered most commonly by cow's milk protein. The usual presenting features are vomiting with lethargy and dehydration in FPIES; bloody and mucous stools in FPIAP; and diarrhea with malabsorption and failure to thrive in FPE. Diagnosis is based on convincing history and resolution of symptoms with food avoidance; confirmatory diagnostic testing other than food challenge is lacking...
August 2015: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/26039942/characteristics-and-prognosis-of-allergic-proctocolitis-in-infants
#10
Aysenur Kaya, Muge Toyran, Ersoy Civelek, Emine Misirlioglu, Ceyda Kirsaclioglu, Can N Kocabas
OBJECTIVES: The dietary protein proctocolitis, also known as allergic proctocolitis (AP), is characterized by the presence of mucoid, frothy, and bloody stools in an otherwise healthy infant. The aim of this study was to describe a group of children with AP, diagnosed according to the criterion-standard method, food challenge to provide clinicians with more information on typical presentation, and an overview on nutritional management strategies and prognosis. METHODS: We collected data on infants with AP in our allergy and gastroenterology outpatient clinics...
July 2015: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26022877/gastrointestinal-food-allergies
#11
Ralf G Heine
Gastrointestinal food allergies present during early childhood with a diverse range of symptoms. Cow's milk, soy and wheat are the three most common gastrointestinal food allergens. Several clinical syndromes have been described, including food protein-induced enteropathy, proctocolitis and enterocolitis. In contrast with immediate, IgE-mediated food allergies, the onset of gastrointestinal symptoms is delayed for at least 1-2 hours after ingestion in non-IgE-mediated allergic disorders. The pathophysiology of these non-IgE-mediated allergic disorders is poorly understood, and useful in vitro markers are lacking...
2015: Chemical Immunology and Allergy
https://www.readbyqxmd.com/read/25976434/food-protein-induced-enterocolitis-syndrome-and-allergic-proctocolitis
#12
REVIEW
Anna Nowak-Węgrzyn
Non-IgE-mediated food allergic disorders account for up to 40% of milk protein allergy in infants and young children. We aim to review the recent literature and to provide an update on diagnosis and management of food protein-induced enterocolitis syndrome (FPIES) and food protein-induced allergic proctocolitis (FPIAP). The peer-reviewed articles indexed in PubMed have been reviewed. FPIES manifests in infants as profuse, repetitive vomiting and lethargy, often with diarrhea, leading to acute dehydration, or weight loss and failure to thrive, in chronic form...
May 2015: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/25956013/non-ige-mediated-gastrointestinal-food-allergy
#13
REVIEW
Anna Nowak-Węgrzyn, Yitzhak Katz, Sam Soheil Mehr, Sibylle Koletzko
Non-IgE-mediated gastrointestinal food-induced allergic disorders (non-IgE-GI-FAs) account for an unknown proportion of food allergies and include food protein-induced enterocolitis syndrome (FPIES), food protein-induced allergic proctocolitis (FPIAP), and food protein-induced enteropathy (FPE). Non-IgE-GI-FAs are separate clinical entities but have many overlapping clinical and histologic features among themselves and with eosinophilic gastroenteropathies. Over the past decade, FPIES has emerged as the most actively studied non-IgE-GI-FA, potentially because of acute and distinct clinical features...
May 2015: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/25229959/-clinical-characteristics-of-infants-with-allergic-proctocolitis-a-retrospective-study-of-96-cases
#14
Hong-Mei Zhao, Jie-Yu You, Bin Xu, Bo-Ping Duan, Hong Ye, Chun-Chun Ren, Li Liu, Zhi-Yong Chen
OBJECTIVE: To study the clinical characteristics of hospitalized infants with allergic proctocolitis, and to provide a scientific basis for early diagnosis and effective treatment of allergic proctocolitis. METHODS: The clinical data of 96 infants with allergic proctocolitis between September 2011 and March 2013 were reviewed retrospectively. Descriptive analysis was performed to assess the clinical characteristics of allergic proctocolitis. RESULTS: The most common clinical manifestation was diarrhea in the 96 infants...
September 2014: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/24750241/outcome-of-infants-presenting-rectal-bleeding-a-retrospective-study-in-a-single-institution
#15
Mari Mori, Yoshikazu Ohtsuka, Asuka Ishida, Susumu Yamazaki, Keisuke Jimbo, Eisuke Inage, Yo Aoyagi, Takahiro Kudo, Ryuyo Suzuki, Toshiaki Shimizu
BACKGROUND: Although rectal bleeding in infancy (RBI) is not a rare phenomenon, the clinical course of RBI is not fully understood. METHODS: To investigate the outcome and pathogenesis of RBI, especially when concomitant with food-protein-induced proctocolitis (FPIP) and neonatal transient eosinophilic colitis (NTEC), 22 neonates with rectal bleeding with FPIP and NTEC from January 2008 to June 2012 were enrolled and their clinical course and mechanisms of inflammation were examined...
December 2014: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/24450450/refractory-proctocolitis-in-the-exclusively-breast-fed-infants
#16
REVIEW
Marina Atanaskovic-Markovic
The arm of this review was to help general pediatricians and primary care physicians in diagnosing and managing cow's milk protein allergy in exclusively breast-fed infants. Allergic proctocolitis is a cause of rectal bleeding in exclusively breast-fed infants aged from 1 to 6 months.It is due to cow's milk protein transferred via breast milk. Diagnosis is based on clinical features and recovery after dietetic therapy. Rectal bleeding generally resolves within 72-96 hours of cow's milk protein maternal avoidance...
March 2014: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/24416045/food-protein-induced-proctocolitis-is-this-allergic-disorder-a-reality-or-a-phantom-in-neonates
#17
REVIEW
Jin-Bok Hwang, Jeana Hong
The etiology of small and fresh rectal bleeding in neonates who are not sick is usually unknown; the only known cause is food protein-induced proctocolitis (FPIPC). It has been recently reported that FPIPC is a rare cause of rectal bleeding in newborns, and most cases have been proved to be due to idiopathic neonatal transient colitis. A recommended strategy for diagnosing suspected FPIPC in neonates is as follows. During the early stage, the etiology of small and fresh rectal bleeding in an otherwise healthy newborn need not be studied through extensive investigations...
December 2013: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/23843067/allergic-proctocolitis-the-clinical-evolution-of-a-transitory-disease-with-a-familial-trend-case-reports
#18
Ulysses Fagundes-Neto, Arnaldo José Ganc
Allergic colitis is a clinical manifestation of food allergy during the first months of life. It is estimated that genetic factors play a role in the expression of this allergic disease. This case report described the clinical progress of infants who were cousins from two distinct family groups with allergic colitis. Five infants under six months of age and of both sexes were studied, with a diagnosis of allergic colitis characterized clinically and histologically by (1) rectal bleeding; (2) exclusion of infectious causes of colitis; (3) disappearance of symptoms after elimination of cow's milk and dairy products from the child's and/or the mother's diet...
April 2013: Einstein
https://www.readbyqxmd.com/read/22644865/non-ige-mediated-gastrointestinal-food-allergies-distinct-differences-in-clinical-phenotype-between-western-countries-and-japan
#19
REVIEW
Ichiro Nomura, Hideaki Morita, Yukihiro Ohya, Hirohisa Saito, Kenji Matsumoto
Non-IgE-mediated gastrointestinal food allergies, including food-protein-induced enterocolitis, enteropathy, proctocolitis and allergic eosinophilic gastroenteritis, seem to be increasing in several regions in the world. However, unlike the case of IgE-mediated food allergy, development of diagnostic laboratory tests and our understanding of the immunological mechanisms involved in non-IgE-mediated gastrointestinal food allergies lag. Although the clinical entities in Western countries have been well established, the clinical phenotypes might differ somewhat among the human races and geographical regions...
August 2012: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/22414488/diagnostic-oral-food-challenges-procedures-and-biomarkers
#20
Kirsi M Järvinen, Scott H Sicherer
Oral food challenge (OFC) is the gold standard for the diagnosis of food allergy. They are conducted to confirm whether an allergy to food exists (initial challenge) or to monitor for resolution of a food allergy. The history of an immediate allergic reaction, when supported by positive tests for specific IgE antibodies to the suspect food, is often sufficient to establish a diagnosis without OFC. Additionally, higher concentrations of food-specific IgE or larger allergy prick skin test wheal sizes correlate with an increased likelihood of a reaction upon ingestion...
September 28, 2012: Journal of Immunological Methods
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