Thomas Greuter, Alex Straumann, Yuniel Fernandez-Marrero, Nina Germic, Aref Hosseini, Apinya Chanwangpong, Shida Yousefi, Dagmar Simon, Margaret H Collins, Christian Bussmann, Mirna Chehade, Evan S Dellon, Glenn T Furuta, Nirmala Gonsalves, Ikuo Hirano, Fouad J Moawad, Luc Biedermann, Ekaterina Safroneeva, Alain M Schoepfer, Hans-Uwe Simon
BACKGROUND: Eosinophilic esophagitis (EoE) variants have been recently characterized as conditions with symptoms of esophageal dysfunction resembling EoE, but absence of significant esophageal eosinophilia. Their disease course and severity have yet to be determined. METHODS: Patients from six EoE-centers with symptoms of esophageal dysfunction, but peak eosinophil counts of <15/hpf in esophageal biopsies and absence of gastro-esophageal reflux disease with at least one follow-up visit were included...
February 6, 2024: Clinical and Translational Gastroenterology