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Eosinophilic gastroenteritis

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https://www.readbyqxmd.com/read/27895976/microscopic-colitis-in-patients-with-mild-duodenal-damage-a-new-clinical-and-pathological-entity-lymphocytic-enterocolitis
#1
Gabriele Antonio Bonagura, Davide Giuseppe Ribaldone, Sharmila Fagoonee, Nicoletta Sapone, Gian Paolo Caviglia, Giorgio Maria Saracco, Marco Astegiano, Rinaldo Pellicano
AIM: To evaluate the potential association between mild duodenal damage and microscopic colitis (MC). METHODS: We retrospectively included 105 consecutive patients with type I Marsh-Oberhuber duodenal damage and negativity for immunoglobulin A anti-endomysium and anti-tissue transglutaminase. The following parameters were analyzed: Sex, age at execution of esophagogastroduodenoscopy, duodenal damage, and number of intraepithelial lymphocytes at biopsies, prevalence of Helicobacter pylori infection, age at execution of colonoscopy, macroscopic and microscopic features of colonoscopy, family history of gastrointestinal and autoimmune diseases, smoking habits, biochemical parameters of inflammation and autoimmunity, use of proton pump inhibitors or nonsteroidal anti-inflammatory drugs, adverse reactions to drugs or foods, pathologies known to be associated with celiac disease or MC, living on a gluten-free diet or on a gluten-low diet for at least 1 mo...
November 15, 2016: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/27867684/eosinophilic-gastroenteritis-approach-to-diagnosis-and-management
#2
REVIEW
Antoine Abou Rached, Weam El Hajj
Eosinophilic gastroenteritis (EGE) is a rare and benign inflammatory disorder that predominantly affects the stomach and the small intestine. The disease is divided into three subtypes (mucosal, muscular and serosal) according to klein's classification, and its manifestations are protean, depending on the involved intestinal segments and layers. Hence, accurate diagnosis of EGE poses a significant challenge to clinicians, with evidence of the following three criteria required: Suspicious clinical symptoms, histologic evidence of eosinophilic infiltration in the bowel and exclusion of other pathologies with similar findings...
November 6, 2016: World Journal of Gastrointestinal Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27843730/abdominal-pain-and-ascites-not-always-related-to-portal-hypertension
#3
Fredy Nehme, Gilbert Kisang, Michael Green, Nathan Tofteland
Eosinophilic gastroenteritis is a rare inflammatory disorder of the gastrointestinal tract with an estimated prevalence of one in 100,000. The typical presentation consists of vague gastrointestinal symptoms with the mucosal involvement of the digestive system. Rarely, it presents as eosinophilic ascites. We report the case of a 22-year-old female who presented with acute onset abdominal pain and ascites. The laboratory studies were remarkable for eosinophilia and the ascitic fluid demonstrated high eosinophilic counts...
October 3, 2016: Curēus
https://www.readbyqxmd.com/read/27796847/four-clusters-of-trichostrongylus-infection-diagnosed-in-a-single-center-in-italy
#4
Dora Buonfrate, Andrea Angheben, Federico Gobbi, Manuela Mistretta, Monica Degani, Zeno Bisoffi
Trichostrongylus spp. are parasites that are seldom recognized as a cause of eosinophilia and gastroenteric symptoms in industrialized countries. The index of suspicion raises when several members of a same household present eosinophilia. We report four clusters of Trichostrongylus infection diagnosed in a single center, in northern Italy. Patients came from four different provinces of three Italian Regions. Some patients presented symptoms (abdominal pain and diarrhea were the most frequent ones, reported by 67 and 42% of our patients, respectively), while other were asymptomatic...
October 27, 2016: Infection
https://www.readbyqxmd.com/read/27721930/eosinophilic-ascites-a-diagnostic-and-therapeutic-challenge
#5
Shefali Agrawal, Sandeep Vohra, Sangeeta Rawat, Vikas Kashyap
Eosinophilic gastroenteritis (EGE) is a rare condition characterized by eosinophilic infiltration of the gastrointestinal tract. Depending on the dominant layer of infiltration it is classified into three types namely, mucosal, muscularis and subserosal. The most uncommon variant is the subserosal type characterized by primarily subserosal disease, eosinophilic ascites and peripheral hypereosinophilia. The clinical features are non-specific with history of atopic predisposition and allergy. Endoscopic biopsy is frequently non-diagnostic due to an uninvolved gastrointestinal mucosa rendering its diagnosis a challenge...
September 27, 2016: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27651195/-clinical-characteristics-and-etiology-of-children-with-hypereosinophilia
#6
Chen Xiaohong, X U Yiping, L U Meiping
OBJECTIVE: To analyze the clinical characteristics and etiology of hypereosinophilia in children. METHODS: Clinical data of 88 children with hypereosinophilia admitted in Children's Hospital of Zhejiang University School of Medicine during April 2009 and May 2015 were retrospectively reviewed. The clinical manifestations, etiologies, and the correlation of disease severity with different etiologies were analyzed. RESULTS: The main clinical manifestations were fever, abdominal pain, cough and/or tachypnea, skin rash, hemafecia and diarrhea, which were observed in 19 (21...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/27613263/eosinophilic-gastroenteritis-a-challenge-to-diagnose-and-treat
#7
Naw April Phaw, Her Hsin Tsai
The patient presented with bloody diarrhoea, and crampy abdominal pains. She was diagnosed with eosinophilic gastroenteritis (EGE) after the finding of persistently high peripheral eosinophil counts and histology of endoscopic biopsies. She responded to steroids but became dependent on it and her symptoms recurred on steroid tapering. There was little improvement with alternative treatment such as budesonides, azathioprine and montelukast. Surprisingly her symptoms improved significantly after she was treated with clarithromycin for chest infection and she was continued on clarithromycin...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27600059/eosinophilic-ascites-a-diagnostic-challenge
#8
Hesham Khalil, Moby Joseph
Eosinophilic ascites is a rare feature of eosinophilic gastroenteritis. We would like to highlight this increasingly recognised diagnosis in a case of unexplained ascites. We present a challenging case of a woman aged 25 years who presented with nausea, vomiting, diarrhoea, generalised abdominal pain and swelling 8-week following delivery of her first baby. Her symptoms were primarily aggravated by eating, and she had also noticed postprandial itching and self-limiting generalised rash. She had a strong history of atopy...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27595440/pneumoperitoneum-in-the-setting-of-pneumatosis-intestinalis-in-children-is-surgery-always-indicated
#9
Julie Galea, Katherine M Burnand, Fiona L Dawson, Chandrasen K Sinha, Dean Rex, Bruce O Okoye
Aim Pneumatosis intestinalis (PI) is a condition in which multiple gas-filled cysts form within the wall of the gastrointestinal tract in either the subserosa or submucosa. The presence of pneumoperitoneum in the presence of PI can present a therapeutic dilemma. The aim of our study was to review our experience and management of this condition. Methods A single-center retrospective study of consecutive children (> 1 year) presenting with a pneumoperitoneum and evidence of PI (2009-2015). Demographics, case notes, microbiology, and imaging were reviewed...
September 5, 2016: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27592279/primary-eosinophilic-gastrointestinal-disorders-in-children-who-have-received-food-oral-immunotherapy
#10
L Á Echeverría-Zudaire, S Fernández-Fernández, A Rayo-Fernández, C Muñóz-Archidona, R Checa-Rodriguez
BACKGROUND: Food oral immunotherapy (OIT) involves the administration of the food allergen causing the symptoms, in order to induce tolerance. Primary eosinophilic gastrointestinal disorders (PEGDs) are characterised by an eosinophil-rich inflammation affecting different locations of the digestive tract. We present a series of patients with PEGDs in a group of children following OIT with milk and/or egg. MATERIAL AND METHODS: A prospective study during the period 2006-2014 was performed in paediatric patients subjected to OIT with milk and/or egg...
November 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27554385/hemangioma-of-the-rectum-how-misleading-can-hematochezia-be
#11
Sofia Vitor, Alexandre Oliveira Ferreira, João Lopes, José Velosa
We present the case of an 18-year-old male patient that was referred to our gastrenterology department with history of intermittent painless hematochezia since childhood. During such instances, he was diagnosed with bowel intussusception, eosinophilic gastroenteritis and inflammatory bowel disease at 4, 6 and 8 years old, respectively. He underwent treatment with 5-aminosalicylic acid for two years, without improvement of symptoms. He was then lost to follow-up until our observation. His physical examination was unremarkable except for digital rectal examination which found a nodular compressible mass by the palpating finger...
August 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27545738/eosinophilic-disorders-of-the-gastrointestinal-tract
#12
REVIEW
Samiullah, Hadi Bhurgri, Umair Sohail
Eosinophilic gastrointestinal disorders represent a spectrum of disorders demonstrating gastrointestinal eosinophilia without any known cause for eosinophilia. Pathogenesis is not clearly established, but immune responses to dietary antigens are implicated. These disorders affect children and adults and are seen in association with allergic disorders. Eosinophilic esophagitis is diagnosed in the setting of mucosal eosinophilia on endoscopic biopsy and symptoms of esophageal dysfunction. Eosinophilic gastroenteritis is also diagnosed with endoscopic biopsies...
September 2016: Primary Care
https://www.readbyqxmd.com/read/27466473/eosinophilic-gastroenteritis-in-a-woman-with-multiple-sclerosis-on-dimethyl-fumarate
#13
Flaminia Purchiaroni, Marco Salvetti, Maria Chiara Buscarinu, Bruno Annibale
No abstract text is available yet for this article.
August 30, 2016: Neurology
https://www.readbyqxmd.com/read/27382945/eosinophilic-gastroenteritis%C3%A2-brief-review
#14
REVIEW
H-M Shih, M-J Bair, H-L Chen, I-T Lin
Eosinophilic gastroenteritis (EGE) is a rare disease which belongs to primary eosinophilic gastrointestinal disorders (primary EGIDs), characterized by an accumulation of eosinophils in the gastrointestinal (GI) tract and is strongly associated with atopy and allergy. The clinical presentations vary depending on the site and depth of eosinophilic intestinal infiltration. Radiology pictures may show irregular thickening of the folds, but these findings can also be present in other conditions like inflammatory bowel disease and lymphoma...
April 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/27347825/comparison-of-the-expression-activity-and-fecal-concentration-of-intestinal-alkaline-phosphatase-between-healthy-dogs-and-dogs-with-chronic-enteropathy
#15
Kaori Ide, Kazuki Kato, Yuki Sawa, Akiko Hayashi, Rei Takizawa, Koji Nishifuji
OBJECTIVE To compare expression, activity, and fecal concentration of intestinal alkaline phosphatase (IAP) between healthy dogs and dogs with chronic enteropathy (CE). ANIMALS 9 healthy university-owned Beagles and 109 healthy client-owned dogs (controls) and 28 dogs with CE (cases). PROCEDURES Cases were defined as dogs with persistent (> 3 weeks) gastrointestinal signs that failed to respond to antimicrobials and anti-inflammatory doses of prednisolone or dietary trials, did not have mechanical gastrointestinal abnormalities as determined by abdominal radiography and ultrasonography, and had a diagnosis of lymphoplasmacytic enteritis or eosinophilic gastroenteritis on histologic examination of biopsy specimens...
July 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27283450/-eosinophilic-gastroenteritis-in-a-teenager-a-rare-diagnosis
#16
Lluïsa Masiques Mas, Maria Teresa Coll Sibina, Josep Sans Tojo, Romina Conti, Miriam Cuatrecases
No abstract text is available yet for this article.
June 6, 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27274524/eosinophilic-gastroenteritis-as-a-rare-cause-of-recurrent-epigastric-pain
#17
Mohammad Taghi Safari, Shabnam Shahrokh, Mohammad Bagher Miri, Mohammad Javad Ehsani Ardakani
Eosinophilic gastroenteritis (EGE) is a rare inflammatory disorder of gastrointestinal tract characterized by eosinophilic infiltration of the bowel wall. It can mimic many gastrointestinal disorders due to its wide spectrum of presentations. Diagnose is mostly based on excluding other disorders and a high suspicion. Here we report a case of 26 year old man with a history of sever epigastric pain followed by nausea, vomiting since a few days before admission with final diagnosis of EGE.
2016: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/27253425/eosinophilic-gastroenteritis-a-state-of-the-art-review
#18
Ming Ming Zhang, Yan-Qing Li
Eosinophilic gastrointestinal disorders are a series of diseases which include eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis, eosinophilic enteritis, and eosinophilic colitis. Among these disorders, eosinophilic gastroenteritis is an uncommon and heterogeneous disease characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of secondary causes, presenting with a variety of gastrointestinal manifestations. Up to now, epidemiology and pathophysiology of eosinophilic gastroenteritis are still unclear...
June 2, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27234270/eosinophilic-gastroenteritis-an-underdiagnosed-condition
#19
Tarik Alhmoud, Joshua Anspach Hanson, Gulshan Parasher
BACKGROUND: Eosinophilic gastroenteritis (EOGE) is a rare idiopathic disease characterized by eosinophil-predominant inflammation of the stomach and/or intestines. Our aims are to determine the epidemiology, clinical features and outcomes of EOGE cases in a tertiary-care hospital. METHODS: Retrospective cohort study of patients with gastrointestinal eosinophilic infiltration from 2004 through 2014. All relevant specimens were reviewed by an expert pathologist. Significant eosinophilic infiltrate was defined as >25 eosinophils/HPF in the stomach or small intestine and >50 eosinophils/HPF in the colon...
September 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27191032/pharmacological-treatment-of-eosinophilic-gastrointestinal-disorders
#20
Susan Hua, Dane Cook, Marjorie M Walker, Nicholas J Talley
INTRODUCTION: Eosinophilic gastrointestinal disorders (EGIDs) are increasingly prevalent chronic inflammatory diseases characterized by eosinophilic infiltration of the gastrointestinal (GI) tract, in the absence of other known causes of eosinophilia. AREAS COVERED: Clinical management of EGIDs is challenging, as there are currently limited therapeutic options available. The most common EGID is eosinophilic esophagitis (EoE), and rarer forms are eosinophilic gastritis, eosinophilic gastroenteritis, and eosinophilic colitis...
September 2016: Expert Review of Clinical Pharmacology
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