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Eosinophilic gastritis

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https://www.readbyqxmd.com/read/27727140/eosinophilic-esophagitis-demographic-clinical-endoscopic-histological-and-allergological-characteristics-in-children-and-teenagers-in-a-region-of-central-spain
#1
E Gómez Torrijos, P Sánchez Miranda, P Donado Palencia, A Castro Jimenez, J Rodriguez Sánchez, Y Mendez Díaz, L Moreno Lozano, R García Rodríguez
BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic inflammatory emerging disease of the oesophagus with immunoallergic aetiology. Until now, few studies about this disease in children and adolescents have been published Objectives: To study the demographic, clinical, serologic, endoscopic-histological and allergologic characteristics of the patients and their atopic and digestive comorbidities. METHODOLOGY: It is an prospective observacional study in children and adolescents (<16 years) assessed in a multidisciplinary specialized eosinpophilic esopahgitis unit in a tertiary referral centre in the central region of Spain carried out between 2011-2015...
October 10, 2016: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/27478819/the-utility-of-endoscopic-biopsies-in-patients-with-normal-upper-endoscopy
#2
Anouar Teriaky, Abdullah AlNasser, Carolyn McLean, James Gregor, Brian Yan
Background and Aims. Upper endoscopy is a valuable tool in the workup of gastrointestinal (GI) complaints. The purpose of this study is to determine cost and yield of taking biopsies in a normal upper GI tract. Methods. This is a retrospective study where all upper GI biopsies were identified between May 2012 and April 2013, at a tertiary care center. Clinical, procedural, and pathology reports were reviewed to identify patient demographics, procedure information, and pathology diagnosis. Results. Biopsies of the upper GI tract were taken in 1297 patients with normal upper endoscopies...
2016: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27412691/simultaneous-or-sequential-gastrectomy-in-pediatric-liver-transplant-recipients
#3
Karina M O Roda, Eduardo A Fonseca, Helry L Candido, Marcel R Benavides, Rogerio C Afonso, Renata Pugliese, Rodrigo Vincenzi, Paulo Chapchap, Joao Seda Neto
The association between LT and gastrectomy is not common. Only two studies reported the gastrectomy/LT association in children. Here, we report three children who underwent LT who required a concomitant or sequential gastrectomy for different reasons. Patient 1, a 16-yr-old boy, during the LT, underwent a partial gastrectomy due to extensive injury to the duodenum. He had a previous and unusual portoenterostomy performed in the duodenum. Bowel reconstruction was performed using an intestinal loop that was first used for the bilio-enteric anastomosis and then connected to the gastric stump...
July 13, 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/27259856/regulatory-t-cells-control-th2-dominant-murine-autoimmune-gastritis
#4
Jessica Harakal, Claudia Rival, Hui Qiao, Kenneth S Tung
Pernicious anemia and gastric carcinoma are serious sequelae of autoimmune gastritis (AIG). Our study indicates that in adult C57BL/6-DEREG mice expressing a transgenic diphtheria toxin receptor under the Foxp3 promoter, transient regulatory T cell (Treg) depletion results in long-lasting AIG associated with both H(+)K(+)ATPase and intrinsic factor autoantibody responses. Although functional Tregs emerge over time during AIG occurrence, the effector T cells rapidly become less susceptible to Treg-mediated suppression...
July 1, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27253425/eosinophilic-gastroenteritis-a-state-of-the-art-review
#5
Ming Ming Zhang, Yan-Qing Li
Eosinophilic gastrointestinal disorders are a series of diseases which include eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis, eosinophilic enteritis, and eosinophilic colitis. Among these disorders, eosinophilic gastroenteritis is an uncommon and heterogeneous disease characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of secondary causes, presenting with a variety of gastrointestinal manifestations. Up to now, epidemiology and pathophysiology of eosinophilic gastroenteritis are still unclear...
June 2, 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27250051/a-possible-case-of-hepatitis-due-to-hypereosinophilic-syndrome
#6
Tomoe Kawamura, Atsushi Hiraoka, Akiko Toshimori, Hidetaro Ueki, Miho Kaneto, Toshihiko Aibiki, Tomonari Okudaira, Hiroka Yamago, Hiromasa Nakahara, Hideomi Tomida, Yoshifumi Suga, Nobuaki Azemoto, Kenichiro Mori, Hideki Miyata, Tomoyuki Ninomiya, Masashi Hirooka, Masanori Abe, Bunzo Matsuura, Yoichi Hiasa, Katsumi Kito, Kojiro Michitaka
A 63-year-old Japanese man whose white blood cell count and total-bilirubin and aminotransferase levels were elevated was referred to our hospital. Computed tomography did not reveal any abnormalities, and there was no evidence of gastritis or colitis on esophagogastroduodenoscopy. Although the patient had no history of drug use or allergies, a high concentration of eosinophils (80%) was noted. A liver biopsy revealed hepatitis with eosinophilic infiltration. The patient's alanine aminotransferase and eosinophil levels improved with the administration of steroids...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27226792/a-player-and-coordinator-the-versatile-roles-of-eosinophils-in-the-immune-system
#7
REVIEW
Hai Long, Wei Liao, Ling Wang, Qianjin Lu
Eosinophils have traditionally been associated with allergic diseases and parasite infection. Research advances in the recent decades have brought evolutionary changes in our understanding of eosinophil biology and its roles in immunity. It is currently recognized that eosinophils play multiple roles in both innate and adaptive immunity. As effector cells in innate immunity, eosinophils exert a pro-inflammatory and destructive role in the Th2 immune response associated with allergic inflammation or parasite infection...
March 2016: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/27191032/pharmacological-treatment-of-eosinophilic-gastrointestinal-disorders
#8
Susan Hua, Dane Cook, Marjorie M Walker, Nicholas J Talley
INTRODUCTION: Eosinophilic gastrointestinal disorders (EGIDs) are increasingly prevalent chronic inflammatory diseases characterized by eosinophilic infiltration of the gastrointestinal (GI) tract, in the absence of other known causes of eosinophilia. AREAS COVERED: Clinical management of EGIDs is challenging, as there are currently limited therapeutic options available. The most common EGID is eosinophilic esophagitis (EoE), and rarer forms are eosinophilic gastritis, eosinophilic gastroenteritis, and eosinophilic colitis...
September 2016: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/26909810/-contact-allergic-gastritis-rare-manifestation-of-a%C3%A2-metal-allergy
#9
REVIEW
C Pföhler, T Vogt, C S L Müller
Only a few cases of contact allergic gastritis in patients with nickel allergy have been reported in the literature. We report a case of probable contact-allergic gastritis in a 46-year-old woman. Clinical examination revealed lichenoid mucosal lesions of the gums adjacent to a bridge and crowns that had been implanted several weeks previously. Since implantation, the patient suffered from gastrointestinal complaints including stomach pain. Gastroscopy and histological investigation of stomach biopsies showed eosinophilic gastritis...
May 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/26889090/wheat-allergy-diagnosis-and-management
#10
REVIEW
Antonella Cianferoni
Triticum aestivum (bread wheat) is the most widely grown crop worldwide. In genetically predisposed individuals, wheat can cause specific immune responses. A food allergy to wheat is characterized by T helper type 2 activation which can result in immunoglobulin E (IgE) and non-IgE mediated reactions. IgE mediated reactions are immediate, are characterized by the presence of wheat-specific IgE antibodies, and can be life-threatening. Non-IgE mediated reactions are characterized by chronic eosinophilic and lymphocytic infiltration of the gastrointestinal tract...
2016: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/26834264/pneumonia-and-gastritis-in-a-cat-caused-by-feline-herpesvirus-1
#11
Glenna F McGregor, Karen Sheehan, Elemir Simko
We report a case of fatal respiratory and gastric herpesvirus infection in a vaccinated, adult cat with no known immunosuppression or debilitation. The disease was characterized by severe necrotizing bronchopneumonia, fibrinonecrotic laryngotracheitis, and multifocal necrotizing gastritis associated with eosinophilic intranuclear inclusion bodies and a large amount of feline herpesvirus-1 antigen detected with immunohistochemistry.
February 2016: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/26709253/eosinophilic-gastrointestinal-disorders-associated-with-autoimmune-connective-tissue-disease
#12
Marie Lecouffe-Desprets, Matthieu Groh, Bruno Bour, Claire Le Jeunne, Xavier Puéchal
OBJECTIVES: To determine the clinical and pathological characteristics of eosinophilic gastrointestinal disease (EGID) associated with autoimmune connective tissue disease (CTD). METHODS: Systematic literature review. RESULTS: Twenty cases of CTD associated with EGID were identified. Systemic lupus erythematosus was the main EGID-associated CTD (35%), followed by rheumatoid arthritis (20%), systemic sclerosis or inflammatory myopathies (15%, each), and Sjögren's syndrome, scleromyositis or other overlapping connective tissue disease (5%, each)...
October 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/26463759/investigation-of-potential-early-histologic-markers-of-pediatric-inflammatory-bowel-disease
#13
Julie A Bass, Craig A Friesen, Amanda D Deacy, Nancy A Neilan, Julia M Bracken, Valentina Shakhnovich, Vivekanand Singh
BACKGROUND: Early manifestations of pediatric inflammatory bowel disease (IBD) can be relatively nonspecific. Initial mucosal biopsies may not be conclusive, delaying the diagnosis until subsequent biopsies demonstrate typical histologic features of IBD. We hypothesized that certain inflammatory cell types may be utilized as early histologic indicators of IBD in children. METHODS: A retrospective analysis compared histologic findings from initially inconclusive or negative endoscopic studies in 22 patients who were subsequently diagnosed with IBD (after diagnostic endoscopy) to those of 20 comparison patients with functional abdominal pain matched for age, gender, and study type...
2015: BMC Gastroenterology
https://www.readbyqxmd.com/read/26310272/-russell-body-gastroenterocolitis-in-a-posttransplant-patient-a-case-report-and-review-of-literature
#14
REVIEW
Vidarshi Muthukumarana, Sheila Segura, Miechelle O'Brien, Rina Siddiqui, Hani El-Fanek
Russell bodies represent a cellular response to overstimulation of plasma cells, leading to the accumulation of abundant, nondegradable, condensed immunoglobulin in dilated rough endoplasmic reticulum cisternae. Russell body gastritis was first described 1998 by Tazawa and Tsutsumi. Since then only 39 cases involving the gastrointestinal tract have been reported in English literature, which include Russell body gastritis, duodenitis, and esophagitis. We report a case of a 44-year-old female with a history of diabetes mellitus, status post kidney and pancreas transplant who presented with multiple episodes of watery diarrhea associated with abdominal pain, nausea, and vomiting...
December 2015: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/26291507/autoimmune-metaplastic-atrophic-gastritis-recognizing-precursor-lesions-for-appropriate-patient-evaluation
#15
Meredith E Pittman, Lysandra Voltaggio, Feriyl Bhaijee, Scott A Robertson, Elizabeth A Montgomery
Autoimmune metaplastic atrophic gastritis (AMAG) is a significant risk factor for pernicious anemia and gastric neoplasia. Still, the histologic features of AMAG are frequently overlooked, especially in the early stages of the disease. The purpose of our study, therefore, was to catalogue the progression of histologic changes that precede the development of AMAG in affected individuals. Over a 2-year period (2012 to 2014), the diagnosis of AMAG was rendered on material from 113 patients seen at Johns Hopkins Hospital (∼1...
December 2015: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/26233430/eosinophilic-esophagitis-and-gastroenteritis
#16
REVIEW
Antonella Cianferoni, Jonathan M Spergel
Eosinophilic gastrointestinal disease (EGID) can be classified as eosinophilic esophagitis (EoE) when the eosinophilia is limited to the esophagus or as eosinophilic gastritis (EG) if it is limited to the gastric tract, eosinophilic colitis (EC) if it is limited to the colon, and eosinophilic gastroenteritis (EGE) if the eosinophilia involves one or more parts of the gastrointestinal tract. EoE is by far the most common EGID. It is a well-defined chronic atopic disease due to a T helper type 2 (Th2) inflammation triggered often by food allergens...
September 2015: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/26155200/spontaneous-and-transgenic-rodent-models-of-inflammatory-bowel-disease
#17
REVIEW
Susan Prattis, Abdo Jurjus
Inflammatory Bowel Disease (IBD) is a multifactorial disorder with many different putative influences mediating disease onset, severity, progression and diminution. Spontaneous natural IBD is classically expressed as Crohn's Disease (CD) and Ulcerative Colitis (UC) commonly found in primates; lymphoplasmocytic enteritis, eosinophilic gastritis and colitis, and ulcerative colitis with neuronal hyperplasia in dogs; and colitis in horses. Spontaneous inflammatory bowel disease has been noted in a number of rodent models which differ in genetic strain background, induced mutation, microbiota influences and immunopathogenic pathways...
June 2015: Laboratory Animal Research
https://www.readbyqxmd.com/read/26113510/first-ultrastructural-observations-on-gastritis-caused-by-physaloptera-clausa-spirurida-physalopteridae-in-hedgehogs-erinaceus-europeaus
#18
T Gorgani-Firouzjaee, A A Farshid, S Naem
Ultrastructural changes of gastritis due to infection with Physaloptera clausa in 12 fresh carcasses of euthanized European hedgehogs (Erinaceus europaeus) collected from different part of Urmia, Iran, in which they were highly populated with this animal, six females and six males were subjected to detail necropsy with special reference to the stomach. Macroscopic changes of stomach were recorded and some of the worms collected. Based on number of parasites present in the stomach, they were divided into light infection, mild infection, and severe infection...
October 2015: Parasitology Research
https://www.readbyqxmd.com/read/26109554/detection-of-epstein-barr-virus-in-inflammatory-pseudotumour-of-the-spleen-a-case-report
#19
Marko Mance, Ivan Romić, Matea Majerović
BACKGROUND: Various types of benign and malignant splenic tumours including hemangiomas, lymphagiomas, hamartomas, hemangiosarcomas, malignant lymphomas and metastatic carcinomas share radiological characteristics making it impossible for a physician to determine the definite aetiology of splenic masses noninvasively without histopathological evaluation. It is important that physicians recognize the importance of a careful and continuous follow-up since inflammatory pseudotumours (IPT) are considered to be tumours with an intermediate malignant potential based on their behaviour when they arise in other locations...
June 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/26030253/gastric-pyloric-gland-adenoma
#20
REVIEW
Maryam Kherad Pezhouh, Jason Y Park
Pyloric gland adenomas are rare neoplasms of the gastrointestinal tract. Gastric pyloric gland adenomas have been shown to arise in chronically damaged mucosa. The neoplastic glands have gastric pyloric gland differentiation and have a tightly packed organization with occasional cystic dilatation. The individual cells are cuboidal to columnar, with eosinophilic to amphophilic cytoplasm and either no apical mucin cap or a poorly formed apical mucin cap. The nuclei are round to oval, with occasional prominent nucleoli...
June 2015: Archives of Pathology & Laboratory Medicine
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