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https://www.readbyqxmd.com/read/28223201/cryptosporidium-pouchitis
#1
Greg S Cohen, Robert J Schenck
No abstract text is available yet for this article.
February 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28221248/early-transcriptomic-changes-in-the-ileal-pouch-provide-insight-into-the-molecular-pathogenesis-of-pouchitis-and-ulcerative-colitis
#2
Yong Huang, Sushila Dalal, Dionysios Antonopoulos, Nathaniel Hubert, Laura H Raffals, Kyle Dolan, Christopher Weber, Jeannette S Messer, Bana Jabri, Albert Bendelac, A Murat Eren, David T Rubin, Mitch Sogin, Eugene B Chang
BACKGROUND: Ulcerative colitis (UC) only involves the colonic mucosa. Yet, nearly 50% of patients with UC who undergo total proctocolectomy with ileal pouch anal anastomosis develop UC-like inflammation of the ileal pouch (pouchitis). By contrast, patients with familial adenomatous polyposis (FAP) with ileal pouch anal anastomosis develop pouchitis far less frequently. We hypothesized that pathogenic events associated with the development of UC are recapitulated by colonic-metaplastic transcriptomic reprogramming of the UC pouch...
March 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28203278/efficacy-of-granulocyte-and-monocyte-apheresis-for-antibiotic-refractory-pouchitis-after-proctocolectomy-for-ulcerative-colitis-an-open-label-prospective-multicentre-study
#3
Takayuki Yamamoto, Toshiaki Tanaka, Tadashi Yokoyama, Takahiro Shimoyama, Hiroki Ikeuchi, Motoi Uchino, Toshiaki Watanabe
BACKGROUND: Granulocyte and monocyte apheresis (GMA) has shown therapeutic efficacy in active ulcerative colitis (UC). We thought that in patients with pouchitis after proctocolectomy for UC, GMA might produce immunological effects in the intestinal mucosa, and improve clinical symptoms. This prospective study was to evaluate the efficacy of GMA for antibiotic-refractory pouchitis after proctocolectomy for UC. METHODS: A total of 13 patients with pouchitis disease activity index (PDAI) > 7 unresponsive to 2 weeks of antibiotic therapy were included...
February 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28199485/successful-treatment-with-ustekinumab-for-chronic-refractory-pouchitis
#4
My-Linh Tran-Minh, Matthieu Allez, Jean-Marc Gornet
No abstract text is available yet for this article.
February 11, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28185664/review-of-the-role-of-probiotics-in-gastrointestinal-diseases-in-adults
#5
Juan José Sebastián Domingo
BACKGROUND: Probiotics may act as biological agents that modify the intestinal microbiota and certain cytokine profiles, which can lead to an improvement in certain gastrointestinal diseases. OBJECTIVES: To conduct a review of the evidence of the role of probiotics in certain gastrointestinal diseases in adults. SEARCH METHODS: Review conducted using appropriate descriptors, filters and limits in the PubMed database (MEDLINE). SELECTION CRITERIA: The MeSH terms used were Probiotics [in the title] AND Gastrointestinal Diseases, with the following limits or filters: Types of study: Systematic Reviews, Meta-Analysis, Guideline, Practice Guideline, Consensus Development Conference (and Consensus Development Conference NIH), Randomized Controlled Trial, Controlled Clinical Trial and Clinical Trial; age: adults (19 or older); language: English and Spanish; in humans, and with at least one abstract...
February 6, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28175184/p628-anti-tnf-therapy-in-refractory-pouchitis-and-crohn-s-disease-like-complications-of-the-pouch-after-ileal-pouch-anal-anastomosis-following-colectomy-for-ulcerative-colitis-a-systematic-review-and-meta-analysis
#6
M Huguet, B Pereira, M Goutte, F Goutorbe, C Allimant, M Reymond, G Bommelaer, A Buisson
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175155/p540-efficacy-of-granulocyte-and-monocyte-apheresis-for-antibiotic-refractory-pouchitis-after-proctocolectomy-for-ulcerative-colitis-an-open-label-prospective-multicentre-study
#7
T Yamamoto, T Tanaka, T Yokoyama, T Shimoyama, H Ikeuchi, M Uchino, T Watanabe
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175146/p478-the-current-place-of-probiotics-in-treatment-of-pouchitis-systematic-review
#8
L Lichtenstein, I Avni, O Ben-Bassat
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172649/p459-obesity-in-patients-with-an-ileoanal-pouch-due-to-ulcerative-colitis-is-not-associated-with-an-increased-risk-for-pouchitis
#9
T Pfeffer-Gik, S Fishman, L Godny, H Tulchinsky, I Dotan
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172463/p158-pouchitis-in-paediatric-ulcerative-colitis-a%C3%A2-multicentre-longitudinal-cohort-study-from-the-porto-ibd-working-group-of-espghan
#10
C Topf-Olivestone, E Orlanski Meyer, O Ledder, M Friedman, I Dotan, L-F Hansen, A Kindermann, A Assa, K-L Kolho, S Kolaček, E Wine, C Strisciuglio, M Aloi, R Hansen, H S Winter, V M Navas-Lόpez, L de Ridder, F Smets, D Turner
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28110377/sulfasalazine-in-prevention-of-pouchitis-after-proctocolectomy-with-ileal-pouch-anal-anastomosis-for-ulcerative-colitis
#11
Eleonora Scaioli, Alessandro Sartini, Elisa Liverani, Richard John Digby, Giampaolo Ugolini, Giancarlo Rosati, Gilberto Poggioli, Davide Festi, Franco Bazzoli, Andrea Belluzzi
BACKGROUND: Pouchitis is the most frequent complication after ileal pouch-anal anastomosis for refractory ulcerative colitis. A non-standardized preventative treatment exists. Sulfasalazine has proved effective in acute pouchitis therapy. AIMS: The aim of this study was to retrospectively evaluate the effect of sulfasalazine in primary prophylaxis of pouchitis after proctocolectomy with ileal pouch-anal anastomosis. METHODS: Data files of patients who underwent total proctocolectomy with ileal pouch-anal anastomosis for refractory ulcerative colitis and/or dysplasia from January 2007 to December 2014, with a follow-up until August 2015, were analyzed...
January 21, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28104319/the-mexican-consensus-on-probiotics-in-gastroenterology
#12
M A Valdovinos, E Montijo, A T Abreu, S Heller, A González-Garay, D Bacarreza, M Bielsa-Fernández, M C Bojórquez-Ramos, F Bosques-Padilla, A I Burguete-García, R Carmona-Sánchez, A Consuelo-Sánchez, E Coss-Adame, J A Chávez-Barrera, M de Ariño, J Flores-Calderón, O Gómez-Escudero, M S González-Huezo, M E Icaza-Chávez, A Larrosa-Haro, M Morales-Arámbula, C Murata, J A Ramírez-Mayans, J M Remes-Troche, T Rizo-Robles, M Peláez-Luna, E M Toro-Monjaraz, A Torre, M E Urquidi-Rivera, R Vázquez, J K Yamamoto-Furusho, F Guarner
INTRODUCTION: Probiotics are frequently prescribed in clinical practice. Their efficacy in treating gastrointestinal disorders is supported by a significant number of clinical trials. However, the correct prescription of these agents is hampered due to a lack of knowledge of the scientific evidence and to the different presentations and microbial compositions of the probiotics that are currently available. AIM: To provide the clinician with a consensus review of probiotics and recommendations for their use in gastroenterology...
January 16, 2017: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/28029082/probiotics-in-curing-allergic-and-inflammatory-conditions-research-progress-and-futuristic-vision
#13
Kuldeep Dhama, Shyma K Latheef, Ashok Kumar Munjal, Rekha Khandia, Hari Abdul Samad, Hafiz M N Iqbal, Sunil K Joshi
BACKGROUND: Probiotics constitute the viable and beneficial microbes, which offer a dietary means to sustain the balance of gastro-intestinal (GI) microflora. Owing to their multiple health benefits, these have recently gained wide attention among researchers for exploring their potential in safeguarding the health of humans and animals. Probiotics could also modulate host-immune responses, thereby help in counteracting the immunological dysfunctions. Probiotics can inhibit the systemic invasion of pathogens entering through the GI mucosa/ oral cavity and have been found to possess effective prophylactic and therapeutic utilities against various infectious pathogens as well as non-infectious diseases and disorders...
December 26, 2016: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28028357/can-probiotics-benefit-children-with-autism-spectrum-disorders
#14
REVIEW
Fernando Navarro, Yuying Liu, Jon Marc Rhoads
Children with autism are commonly affected by gastrointestinal problems such as abdominal pain, constipation and diarrhea. In recent years, there has been a growing interest in the use of probiotics in this population, as it hypothetically may help to improve bowel habits and the behavioral and social functioning of these individuals. The gut microbiome plays an important role in the pathophysiology of organic as well as functional gastrointestinal disorders. Microbial modification with the use of antibiotics, probiotics, and fecal transplantation have been effective in the treatment of conditions such as recurrent Clostridium difficile infection, pouchitis, and irritable bowel syndrome...
December 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28008631/systematic-review-with-meta-analysis-the-management-of-chronic-refractory-pouchitis-with-an-evidence-based-treatment-algorithm
#15
REVIEW
J P Segal, N S Ding, G Worley, S Mclaughlin, S Preston, O D Faiz, S K Clark, A L Hart
BACKGROUND: Restorative proctocolectomy with ileal pouch anal anastomosis (IPAA) is considered the procedure of choice in patients with ulcerative colitis (UC) refractory to medical therapy. The incidence of pouchitis is 40% at 5 years. Ten to 15% of patients with pouchitis experience chronic pouchitis. AIM: To determine the efficacy of medical therapies for the treatment of chronic refractory pouchitis in patients undergoing IPAA for UC. METHODS: A systematic computer-assisted search of the on-line bibliographic database MEDLINE and EMBASE was performed between 1966 and February 2016...
December 23, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28005973/methodological-quality-assessment-of-meta-analyses-and-systematic-reviews-of-probiotics-in-inflammatory-bowel-disease-and-pouchitis
#16
Jinpei Dong, Guigen Teng, Tiantong Wei, Wen Gao, Huahong Wang
BACKGROUND: Probiotics are widely used for the induction and maintenance of remission in inflammatory bowel disease (IBD) and pouchitis. There are a large number of meta-analyses (MAs)/ systematic reviews (SRs) on this subject, the methodological quality of which has not been evaluated. OBJECTIVES: This study aimed to evaluate the methodological quality of and summarize the evidence obtained from MAs/SRs of probiotic treatments for IBD and pouchitis patients. METHODS: The PubMed, EMBASE, Cochrane Library and China National Knowledge Infrastructure (CNKI) databases were searched to identify Chinese and English language MAs/SRs of the use of probiotics for IBD and pouchitis...
2016: PloS One
https://www.readbyqxmd.com/read/27991017/-proctocolectomy-with-j-pouch-ileo-anal-anastomosis-performed-with-pph-stapler-our-experiences-after-88-cases
#17
Csaba Berki, Elemér Mohos, György Réti, Tamás Kovács, Zoltán Jánó, József Mohay, Sándor Horváth, Gábor Bognár, Krisztina Bene, Myroslav Horzov, Gábor Sándor, Gábor Tornai, Petra Mohos, Péter Szenkovits, Tibor Nagy, Csaba Orbán, Vivien Herpai, Attila Nagy
AIM: Ulcerative colitis (CU) or Familiar Polyposis (FAP) can be the indication for proctocolectomy reconstructed with J pouch. The complete removal of the colon mucosa is essential regarding the late complications and at the same time the atraumatic surgical technique is very important concerning on the long term functional results. Both aspects seems to be answered by the stapled ileo-anal anastomosis using a "procedure for prolaps and haemorrhoids (PPH)" stapler applied by us since 2000...
December 2016: Magyar Sebészet
https://www.readbyqxmd.com/read/27988458/tripterygium-wilfordii-polyglycosidium-ameliorates-pouchitis-induced-by-dextran-sulfate-sodium-in-rats
#18
Senyang Gao, Xiaoyan Wu, Yingying Zhang, Kaiyu Li, Litian Wang, Gang Liu
BACKGROUND: The aim of this study was to investigate the therapeutic effects of Tripterygium wilfordii polyglycosidium (TWP) to rats with dextran sulfate sodium (DSS)-induced pouchitis and its possible mechanism. METHODS: Sprague-Dawley rats underwent surgery of ileal pouch anal anastomosis (IPAA) and pouchitis was induced by DSS. Rats were randomly divided into no intervention (NI), normal saline (NS) and TWP groups. Rats were lavaged with normal saline (3ml/day in NS group) or TWP (12mg/kg/day in TWP group) for 7days...
February 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/27935837/patient-specific-bacteroides-genome-variants-in-pouchitis
#19
Joseph H Vineis, Daina L Ringus, Hilary G Morrison, Tom O Delmont, Sushila Dalal, Laura H Raffals, Dionysios A Antonopoulos, David T Rubin, A Murat Eren, Eugene B Chang, Mitchell L Sogin
: A 2-year longitudinal microbiome study of 22 patients who underwent colectomy with an ileal pouch anal anastomosis detected significant increases in distinct populations of Bacteroides during 9 of 11 patient visits that coincided with inflammation (pouchitis). Oligotyping and metagenomic short-read annotation identified Bacteroides populations that occurred in early samples, bloomed during inflammation, and reappeared after antibiotic treatment. Targeted cultivation of Bacteroides isolates from the same individual at multiple time points and from several patients detected subtle genomic changes, including the identification of rapidly evolving genomic elements that differentiate isogenic strains of Bacteroides fragilis from the mucosa versus lumen...
November 15, 2016: MBio
https://www.readbyqxmd.com/read/27930413/efficacy-of-vedolizumab-in-patients-with-antibiotic-and-anti-tumor-necrosis-alpha-refractory-pouchitis
#20
Jessica Philpott, Jean Ashburn, Bo Shen
No abstract text is available yet for this article.
January 2017: Inflammatory Bowel Diseases
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