Vincenzo Villanacci, Alessandro Vanoli, Giuseppe Leoncini, Giovanni Arpa, Tiziana Salviato, Luca Reggiani Bonetti, Carla Baronchelli, Luca Saragoni, Paola Parente
Celiac disease is a multi-factorial chronic inflammatory intestinal disease, characterized by malabsorption resulting from mucosal injury after ingestion of wheat gluten or related rye and barley proteins. Inappropriate T-cell-mediated immune response against ingested gluten in genetically predisposed people, leads to characteristic histological lesions, as villous atrophy and intraepithelial lymphocytosis. Nevertheless, celiac disease is a comprehensive diagnosis with clinical, serological and genetic characteristics integrated with histological features...
September 2020: Pathologica