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Solid pseudopapillary tumor

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https://www.readbyqxmd.com/read/29290920/extrapancreatic-solid-pseudopapillary-neoplasm-followed-by-multiple-metastases-case-report
#1
Hao Wu, Yan-Fen Huang, Xiang-Hong Liu, Mei-Hua Xu
Solid pseudopapillary neoplasm (SPN), also known as Gruber-Frantz tumor, is a rare form of neoplasm that almost exclusively occurs in the pancreas and in young females. While the potential of malignancy is low for SPN, these tumors can mimic other diseases and require a meticulous investigation and a standard treatment by total surgical resection. We present an unusual case of SPN arising in the mesentery of a 40-year-old man with subsequent multiple metastases. Histopathological examination showed similar properties of the mesenteric neoplasm to those of SPN in pancreas...
December 15, 2017: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29287021/does-computed-tomography-have-the-ability-to-differentiate-aggressive-from-nonaggressive-solid-pseudopapillary-neoplasm
#2
Ashita Rastogi, Mathew Assing, Mellisa Taggart, Brinda Rao, Jia Sun, Khaled Elsayes, Eric Tamm, Priya Bhosale
OBJECTIVE: The aim of the study was to assess the ability of contrast-enhanced computed tomography (CECT) to differentiate aggressive from nonaggressive solid pseudopapillary neoplasms (SPNs). MATERIALS AND METHODS: Forty treatment-naive patients with pathologically proven pancreatic SPNs were included. Imaging characteristics were determined by consensus of 3 radiologists blinded to histopathologic aggressiveness. All patients underwent 4-phase CECT using a pancreatic protocol...
December 28, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29277262/pancreatectomies-for-pancreatic-neoplasms-in-pediatric-and-adolescent-age-a-single-institution-experience
#3
Chiara Scandavini, Roberto Valente, Elena Rangelova, Ralf Segersvärd, Urban Arnelo, Johan Permert, Pär-Johan Svensson, Jakob Stenman, Marco Del Chiaro
BACKGROUND: There are very few data in the current literature regarding the short- and long-term outcome of surgery for pediatric pancreatic tumors (PPT). No data are available on the impact of pancreatic surgery on the children's growth. METHODS: This is a retrospective cohort study on a consecutive series of pediatric/adolescent patients who underwent pediatric surgery at Karolinska University Hospital from January 2005 to July 2017. RESULTS: Overall 14 pancreatic operations were performed in 13 patients...
December 19, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29241991/pancreatic-cyst-fluid-glucose-rapid-inexpensive-and-accurate-diagnosis-of-mucinous-pancreatic-cysts
#4
Rosalie A Carr, Michele T Yip-Schneider, Rachel E Simpson, Scott Dolejs, Justine G Schneider, Huangbing Wu, Eugene P Ceppa, Walter Park, C Max Schmidt
BACKGROUND: The most widely accepted biochemical test for preoperative differentiation of mucinous from benign, nonmucinous pancreatic cysts is cyst fluid carcinoembryonic antigen. However, the diagnostic accuracy of carcinoembryonic antigen ranges from 70% to 86%. Based on previous work, we hypothesize that pancreatic cyst fluid glucose may be an attractive alternative to carcinoembryonic antigen. METHODS: Pancreatic cyst fluid was collected during endoscopic or operative intervention...
December 11, 2017: Surgery
https://www.readbyqxmd.com/read/29241452/pancreatic-schwannoma-a-case-report-and-an-updated-40-year-review-of-the-literature-yielding-68-cases
#5
Yuntong Ma, Bingqi Shen, Yingmei Jia, Yanji Luo, Yisu Tian, Zhi Dong, Wei Chen, Zi-Ping Li, Shi-Ting Feng
BACKGROUND: Pancreatic schwannoma is a rare tumor. Preoperative diagnosis of pancreatic schwannoma is challenging due to its tendency to mimic other lesions of the pancreas. We describe a case of pancreatic schwannoma and present a review of the cases currently reported in the English literature to identify characteristics of pancreatic schwannoma on imaging. CASE PRESENTATION: A 53-year-old male presented with a history of intermittent periumbilical abdominal pain and lower back pain for 1 week...
December 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29240036/solid-pseudopapillary-neoplasm-of-the-pancreas-in-children-and-adults-a-national-study-of-369-patients
#6
Harold J Leraas, Jina Kim, Zhifei Sun, Brian Ezekian, Brian C Gulack, Christopher R Reed, Elisabeth T Tracy
BACKGROUND: Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor in children, with current evidence limited to single-center studies. We examined treatment and clinical outcomes for pediatric and adult SPN with a national data set. METHODS: The 2004 to 2013 National Cancer Data Base was queried to identify all patients diagnosed with SPN. The cohort was stratified by age (pediatric and adult) defined as below 18 years and 18 years and above, respectively...
December 12, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29212159/lef1-tfe3-and-ar-are-putative-diagnostic-markers-of-solid-pseudopapillary-neoplasms
#7
Eun Kyung Kim, Mi Jang, Minhee Park, Hoguen Kim
The diagnosis of solid pseudopapillary neoplasms (SPNs) is challenging because some SPNs share many similar morphological and immunohistochemical features with other pancreatic neoplasms. In this study, we investigated potential diagnostic markers of SPN. Based on the SPN-specific upregulated genes from a previous DNA microarray and proteome study, we selected six immunohistochemical markers [beta-catenin, androgen receptor (AR), lymphoid enhancer-binding factor 1 (LEF1), transcription factor for immunoglobulin heavy-chain enhancer 3 (TFE3), fused in sarcoma (FUS), and WNT inhibitory factor 1 (WIF-1)]...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29191273/rare-tumors-and-lesions-of-the-pancreas
#8
REVIEW
John A Stauffer, Horacio J Asbun
There are a few entities that account for most solid and cystic masses of the pancreas. The pancreas harbors a wide array of diseases, including adenocarcinoma, and its variants, such as anaplastic and adenosquamous carcinoma. Other neoplasms include acinar cell carcinoma, solid pseudopapillary tumor, and sarcomas. Benign lesions include hamartomas, hemangiomas, lymphangioma, and plasmacytoma. Isolated metastases include renal cell carcinoma, melanoma, and other carcinomas. Benign inflammatory conditions, such as autoimmune pancreatitis and groove pancreatitis can also mimic solid neoplasms of the pancreas...
February 2018: Surgical Clinics of North America
https://www.readbyqxmd.com/read/29153366/papillary-glioneuronal-tumors-a-radiopathologic-correlation
#9
Nishtha Yadav, Shilpa Rao, Jitender Saini, Chandrajit Prasad, Anita Mahadevan, Nishanth Sadashiva
OBJECTIVE: Papillary glioneuronal tumors (PGNT) are a rare and recently recognized tumor entity. The neuroimaging findings were reviewed to determine if any specific findings emerge to assist a preoperative diagnosis of PGNT. MATERIALS AND METHODS: Seven histologically confirmed cases of PGNT were evaluated from 2004 to 2014. Clinical, neuroimaging and histological findings were reviewed and tabulated. RESULTS: Headache and seizures were observed in 4 patients (57...
December 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29137016/binding-pancreaticogastrostomy-anastomosis-in-central-pancreatectomy-a-single-center-experience
#10
Pengcheng Kang, Zhidong Wang, Kaiming Leng, Xiangyu Zhong, Hao Wang, Ming Wan, Sheng Tai, Yunfu Cui
A growing number of central pancreatectomies are performed. However, reconstruction of pancreaticoenteral digestive continuity after central pancreatectomy remains debated. This study evaluates the short-term outcomes of binding pancreaticogastrostomy anastomosis in central pancreatectomy.We have reviewed our experience with 52 patients who underwent binding pancreaticogastrostomy following central pancreatectomy from February 2009 to March 2015. Indication includes 6 noninvasive intraductal papillary mucinous neoplasms, 11 neuroendocrine tumors, 12 solid pseudopapillary tumor, 9 serous cystadenoma, 6 mucinous cystadenoma, and 8 focal pancreatic traumas...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29130012/10-year-old-female-with-acute-abdominal-pain-with-pancreatic-mass
#11
Charles K Powers, Molly Posa, Dhanashree Rajderkar, Jaclyn Otero
A previously healthy 10-year-old female presented to a local emergency department following three days of nausea and vomiting diagnosed with a solid pseudopapillary tumor. Solid pseudopapillary neoplasms are a rare form of pancreatic cystic neoplasm that typically presents in young females in their 20-30s and are very rare in children. These neoplasms often present as an asymptomatic tumor found on incidental imaging. When symptomatic they most commonly present with abdominal pain and can also cause a palpable abdominal mass, weight loss, gastrointestinal obstruction, and nausea and vomiting...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29115095/radiologic-findings-in-extrapancreatic-solid-pseudopapillary-tumor-with-aggressive-behavior-a-case-report
#12
Hye Won Choi, Hyun Jeong Park, Soon Auk Hong, Sung Bin Park, Eun Sun Lee, Hye Shin Ahn, Jong Beum Lee, Byung Ihn Choi
Solid pseudopapillary tumor (SPT) is a low grade malignant tumor in the pancreas, and extrapancreatic SPT is extremely rare. We report a case of a 61-year-old woman who complained abdominal pain with diffuse tenderness. She was diagnosed with extrapancreatic SPT with extensive peritoneal dissemination and hepatic metastases. Although a few cases have reported imaging findings of extrapancreatic SPT, there have been no reports of extrapancreatic SPT with aggressive tumor behavior and dismal prognosis. Although imaging features closely resembled those of classical pancreatic SPTs, malignant transformation of extrapancreatic SPT should be considered when focal discontinuity of the tumor capsule with ill-defined margin and invasion of adjacent structures were identified...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29094047/solid-pseudopapillary-neoplasm-of-the-pancreas-clinicopathologic-feature-risk-factors-of-malignancy-and-survival-analysis-of-53-cases-from-a-single-center
#13
He Song, Ming Dong, Jianping Zhou, Weiwei Sheng, Banghua Zhong, Wei Gao
Introduction: Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor of low malignant potential. The aim of this study was designed to evaluate the clinicopathologic feature, predictive factors of malignancy, and survival from experience of a single center. Methods: 53 consecutive patients who underwent surgery for a pathologically definitive SPN were retrospectively reviewed. Results: A total of 53 cases included 7 male cases and 46 female cases with the median age of 35...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29073488/solid-pseudopapillary-tumor-of-the-pancreas-clinical-features-and-imaging-findings
#14
Dong-Li Li, Hong-Sheng Li, Yi-Kai Xu, Quan-Shi Wang, Rui-Ying Chen, Fang Zhou
This study aimed to report clinical features and CT, MRI, PET/CT findings of solid pseudopapillary tumor (SPT) of the pancreas. Thirty-four patients with pathologically proven SPT were retrospectively reviewed. Most patients were asymptomatic. SPTs in male patients mainly appeared as solid and near solid tumors. Mixed tumors and cystic tumors had larger size than solid and near solid tumors. Solid tumors and solid part of mixed tumors were T2 hyperintense and T1 hypointense and had progressive enhancement. Four tumors (80%) showed markedly even or uneven 18F-FDG uptake...
October 13, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29045075/immunocytochemistry-for-sox-11-and-tfe3-as-diagnostic-markers-for-solid-pseudopapillary-neoplasms-of-the-pancreas-in-fna-biopsies
#15
Wen-Chi Foo, Grant Harrison, Xuefeng Zhang
BACKGROUND: Solid pseudopapillary neoplasms (SPNs) of the pancreas are rare malignant tumors that can be sampled via endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). Although diagnosing SPNs can be straightforward in cases with a classic morphology and a typical immunoprofile, challenges can occur with morphologic variants or limited specimens. Recently, 2 immunohistochemical stains, SRY-related high-mobility group box 11 (SOX-11) and transcription factor E3 (TFE3), have been demonstrated to be highly sensitive and specific for SPNs in pancreatic resection specimens...
November 2017: Cancer
https://www.readbyqxmd.com/read/29038855/imaging-mimics-of-pancreatic-ductal-adenocarcinoma
#16
Namita S Gandhi, Myra K Feldman, Ott Le, Gareth Morris-Stiff
Pancreatic ductal adenocarcinoma is the most common primary malignancy of the pancreas. The classic imaging features are a hypovascular mass with proximal ductal dilatation. Different pancreatic pathologies can mimic the imaging appearance of carcinoma including other tumors involving the pancreas (pancreatic neuroendocrine tumors, lymphoma, metastasis, and rare tumors like pancreatic acinar cell carcinoma and solid pseudopapillary tumors), inflammatory processes (chronic pancreatitis and autoimmune pancreatitis), and anatomic variants (annular pancreas)...
October 16, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28990381/enucleation-of-non-invasive-tumors-in-the-proximal-pancreas-indications-and-outcomes-compared-with-standard-resections
#17
Wen-Jie Lu, Hao-Lei Cai, Ma-Dong Ye, Yu-Lian Wu, Bin Xu
OBJECTIVE: The aim of this study was to evaluate the safety and efficiency of enucleation (EU) for proximal pancreatic non-invasive neoplasms. METHODS: Patients with solitary non-invasive neoplasms in the proximal pancreas from January 1998 to April 2014 at the Second Affiliated Hospital of Zhejiang University, Hangzhou, China were included. Different operations and outcomes were analyzed. RESULTS: A total of 123 patients were enrolled. Forty patients (32...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28900331/solid-pseudopapillary-tumor-of-pancreas-a-case-report-and-review-of-literature
#18
Gursev Sandlas, Charu Tiwari
Solid pseudopapillary neoplasm of the pancreas is one of the rarest forms of pancreatic neoplasm. It was also known as Franz's tumor or Hamoudi tumor until WHO labeled it as solid pseudopapillary tumor (SPT) in 1996. It typically affects young non-Caucasian females in their second or third decade of life. Treatment involves complete excision of the tumor which results in complete cure in majority of the cases. We present here a report of 11-year-old girl with SPT and also do a review of literature for this rare tumor...
April 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28877823/clinical-and-magnetic-resonance-imaging-features-of-solid-pseudopapillary-tumor-of-the-pancreas-in-male-patients
#19
Yan Zhong, Hai-Yi Wang, En-Qiang Linghu, Yu-Fa Sun, Wei Xu, Lu Ma, Hui-Yi Ye
Objective To analyze the clinical and magnetic resonance imaging(MRI)findings of solid pseudopapillary tumor(SPT)of the pancreas in male patients. Methods Clinical and MRI features of 51 patients with pathologically-proved SPT were retrospectively analyzed.The following MRI features of the lesions were analyzed:location,maximal diameter,shape,margin,capsule,solid and cystic components,signal intensity characteristics,and enhancement patterns.Results The average maximal diameter of the SPT in male patients was significantly smaller [(3...
August 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28861890/high-grade-renal-cell-carcinoma-with-emperipolesis-clinicopathological-immunohistochemical-and-molecular-genetic-analysis-of-14-cases
#20
Pavla Rotterova, Petr Martinek, Reza Alaghehbandan, Kristyna Prochazkova, Ivan Damjanov, Joanna Rogala, Saul Suster, Delia Perez-Montiel, Isabel Alvarado-Cabrero, Maris Sperga, Marian Svajdler, Kvetoslava Michalova, Kristyna Pivovarcikova, Ondrej Daum, Milan Hora, Martin Dusek, Ondrej Ondic, Adela Stehlikova, Michal Michal, Ondrej Hes
Emperipolesis has recently been described as a constant feature of "biphasic squamoid" papillary renal cell carcinoma (BPRCC). We also noticed this in some high-grade (HG) RCC, which promoted the present study to estimate the incidence of emperipolesis in RCCs and to describe them in further detail. 14 cases of HGRCC showing emperipolesis were retrieved from our registry. Microscopic examination of filed slides was supplemented with immunohistochemical and molecular-genetic analyses using paraffin embedded tissue...
September 1, 2017: Histology and Histopathology
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