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Atrophic gastritis

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https://www.readbyqxmd.com/read/28077338/10-day-bismuth-containing-quadruple-therapy-is-effective-as-first-line-therapy-for-helicobacter-pylori-related-chronic-gastritis-a-prospective-randomized-study-in-china
#1
Liangjing Wang, Zhenghua Lin, Shujie Chen, Jun Li, Chun Xiao Chen, Zhiming Huang, Bin Ye, Jin Ding, Wei Li, Lunpo Wu, Ying Jiang, Lina Meng, Qin Du, Jianmin Si
OBJECTIVES: To investigate the effectiveness of 10-day bismuth-containing quadruple (B-quadruple) treatment as first-line therapy in patients with Helicobacter pylori related chronic gastritis. METHODS: Randomized control trial conducted from Oct. 2011 to Dec. 2013 in Zhejiang, China, including patients with H. pylori-related chronic gastritis who were randomly given either 10-day omeprazole-based triple (OM-triple, omeprazole 20 mg twice daily, clarithromycin 500 mg twice daily and amoxicillin 1g twice daily), or 10-day B-quadruple therapy (OM-triple + bismuth subcitrate 120 mg four times daily)...
January 7, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28072871/atrophic-and-metaplastic-progression-in-the-background-mucosa-of-patients-with-gastric-adenoma
#2
Hee Kyong Na, Charles J Cho, Suh Eun Bae, Jeong Hoon Lee, Young Soo Park, Ji Yong Ahn, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Se Jin Jang, Hwoon-Yong Jung
BACKGROUND: In patients with adenoma, assessing premalignant changes in the surrounding mucosa is important for surveillance. This study evaluated atrophic and metaplastic progression in the background mucosa of adenoma or early gastric cancer (EGC) cases. METHODS: Among 146 consecutive patients who underwent endoscopic resection for intestinal-type gastric neoplasia, the adenoma group included 56 patients with low-grade dysplasia and the ECG group included 90 patients with high-grade dysplasia or invasive carcinoma...
2017: PloS One
https://www.readbyqxmd.com/read/28070825/prevalence-and-predictors-of-giardia-in-the-united-states
#3
Haley M Zylberberg, Peter H R Green, Kevin O Turner, Robert M Genta, Benjamin Lebwohl
BACKGROUND: Infection with Giardia lamblia is a common cause of diarrheal disease in the developing and industrialized world. AIMS: We aimed to assess the prevalence of giardiasis in the United States (US) among patients with duodenal biopsies, investigating demographic and clinical factors associated with this condition. METHODS: We conducted a cross-sectional study of patients with duodenal biopsies submitted to a national pathology laboratory between January 2, 2008, and December 31, 2015...
January 9, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28067243/association-of-polymorphisms-in-three-pri-mirnas-that-target-pepsinogen-c-with-the-risk-and-prognosis-of-gastric-cancer
#4
Ye-Feng Wu, Qian Xu, Cai-Yun He, Ying Li, Jing-Wei Liu, Na Deng, Li-Ping Sun, Yuan Yuan
We aimed to explore the associations of polymorphisms in three microRNAs (miRNAs) (let-7e rs8111742, miR-365b rs121224 and miR-4795 rs1002765) that target PGC with the risk and prognosis of gastric cancer/atrophic gastritis. Sequenom's MassArray was used to genotype the miRNA polymorphisms in 724 gastric cancer cases, 862 atrophic gastritis cases and 862 controls in a Chinese population. We found that let-7e rs8111742 and miR-4795 rs1002765 were associated with the risk of gastric cancer in the H. pylori-positive subgroup...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28050349/intra-abdominal-abscesses-by-lactococcus-lactis-ssp-cremoris-in-an-immunocompetent-adult-with-severe-periodontitis-and-pernicious-anemia
#5
Konstantinos Fragkiadakis, Petros Ioannou, Emmanouil Barbounakis, George Samonis
We report the case of an immunocompetent man who presented with fever and abdominal pain and was found to have a hepatic abscess and a peri-renal abscess with a computerized tomography scan. The hepatic abscess was drained percutaneously and cultures revealed the presence of Lactococcus lactis that was sensitive to penicillin. The patient was successfully treated with ceftriaxone and metronidazole with resolution of the abscesses. Further work-up revealed atrophic gastritis, vitamin B12 deficiency, periodontitis and gingivitis, suggesting a possible site of entry for the development of the abscesses...
2017: IDCases
https://www.readbyqxmd.com/read/28049442/analyzing-the-influence-of-gastric-intestinal-metaplasia-on-gastric-ulcer-healing-in-helicobacter-pylori-infected-patients-without-atrophic-gastritis
#6
Li-Wei Chen, Liang-Che Chang, Chung-Ching Hua, Bor-Jen Hsieh, Shuo-Wei Chen, Rong-Nan Chien
BACKGROUND: Gastric epithelial hyper-proliferation was reported in patients with Helicobacter pylori (H. pylori)-infected gastric mucosa with intestinal metaplasia (IM) changes. In patients with gastric ulcer (GU) and IM, the GU may have a different healing rate in comparison to patients without IM. This study aimed to compare the difference in GU healing between H. pylori-infected patients with IM and those without IM. METHODS: We retrospectively analyzed patients at the Keelung Chung Gung Memorial Hospital during the period from March 2005 to January 2011...
January 3, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28040990/the-challenging-diagnosis-of-autoimmune-atrophic-gastritis
#7
Marco Vincenzo Lenti, Emanuela Miceli, Donatella Padula, Antonio Di Sabatino, Gino Roberto Corazza
No abstract text is available yet for this article.
December 31, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28034664/cost-of-detecting-gastric-neoplasia-by-surveillance-endoscopy-in-atrophic-gastritis-in-italy-a-low-risk-country
#8
Edith Lahner, Cesare Hassan, Gianluca Esposito, Marilia Carabotti, Angelo Zullo, Mario Dinis-Ribeiro, Bruno Annibale
BACKGROUND: Atrophic gastritis (AG) is at increased risk of gastric neoplasia, thus surveillance gastroscopy has been proposed. AIMS: To assess cost of detecting gastric neoplasias by surveillance endoscopy according to identified risk factors in Italy. METHODS: Post-hoc analysis of a cohort study including 200 AG-patients from Italy followed up for a mean of 7.5 (4-23.4) years was done. Considered risk factors were: age >50years, extensive atrophy, pernicious anaemia, OLGA-OLGIM scores 3-4 at diagnosis...
December 15, 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28032715/helicobacter-pylori-infection-chronic-corpus-atrophic-gastritis-and-pancreatic-cancer-risk-in-the-european-prospective-investigation-into-cancer-and-nutrition-epic-cohort-a-nested-case-control-study
#9
Jiaqi Huang, Ulrika Zagai, Göran Hallmans, Olof Nyrén, Lars Engstrand, Rachael Stolzenberg-Solomon, Eric J Duell, Kim Overvad, Verena A Katzke, Rudolf Kaaks, Mazda Jenab, Jin Young Park, Raul Murillo, Antonia Trichopoulou, Pagona Lagiou, Christina Bamia, Kathryn E Bradbury, Elio Riboli, Dagfinn Aune, Konstantinos K Tsilidis, Gabriel Capellá, Antonio Agudo, Vittorio Krogh, Domenico Palli, Salvatore Panico, Elisabete Weiderpass, Anne Tjønneland, Anja Olsen, Begoña Martínez, Daniel Redondo-Sanchez, Maria-Dolores Chirlaque, Petra Hm Peeters, Sara Regnér, Björn Lindkvist, Alessio Naccarati, Eva Ardanaz, Nerea Larrañaga, Marie-Christine Boutron-Ruault, Vinciane Rebours, Amélie Barré, H B As Bueno-de-Mesquita, Weimin Ye
The association between H. pylori infection and pancreatic cancer risk remains controversial. We conducted a nested case-control study with 448 pancreatic cancer cases and their individually matched control subjects, based on the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, to determine whether there was an altered pancreatic cancer risk associated with H. pylori infection and chronic corpus atrophic gastritis. Conditional logistic regression models were applied to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs), adjusted for matching factors and other potential confounders...
December 29, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28025702/characteristics-of-gastric-cancer-in-negative-test-of-serum-anti-helicobacter-pylori-antibody-and-pepsinogen-test-a-multicenter-study
#10
Mariko Kiso, Masaharu Yoshihara, Masanori Ito, Kazuhiko Inoue, Katsuaki Kato, Shigemi Nakajima, Katsuhiro Mabe, Masao Kobayashi, Naomi Uemura, Tomoyuki Yada, Masashi Oka, Takashi Kawai, Tomoyuki Boda, Takahiro Kotachi, Kazuhiko Masuda, Shinji Tanaka, Kazuaki Chayama
BACKGROUND AND AIM: The serological risk prediction system combines the pepsinogen test and anti-Helicobacter pylori (H. pylori) antibody determination. In this system, chronic atrophic gastritis (CAG) is diagnosed using the pepsinogen test. Patients who are H. pylori negative and pepsinogen negative are classified into group A, are assumed to be H. pylori uninfected, and are at an extremely low risk for gastric cancer. However, gastric cancers are detected in this group. The aim of this study is to clarify the clinicopathological status of group A patients with gastric cancer...
December 26, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/28004477/revisiting-autoimmune-gastritis-in-children-and-adolescents-with-type-1-diabetes
#11
Alix Besançon, Bénédicte Michaud, Jacques Beltrand, Tania Goncalves, Jean-Philippe Jais, Michel Polak, Lucienne Chatenoud, Jean-Jacques Robert
OBJECTIVE: Assess the frequency of anti-H(+) /K(+) adenosine triphosphatase (ATPase) autoantibodies (AAB) and symptoms of autoimmune gastritis in children and adolescents with type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS: Anti-H(+) /K(+) ATPase AAB were measured in 402 children and adolescents (210 boys and 192 girls, 11.1 ± 4.5 years) treated for T1D (screened positive for β-cell AAB), along with search of symptoms of anemia (hemoglobin, serum iron, and ferritin levels) and gastric pain...
December 22, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/28003849/conifer-green-needle-complex-in-patients-with-precancerous-gastric-lesions-an-observational-pilot-study
#12
Vladimir Bespalov, Alexander Sherbakov, Viktor Novik, Valentin Kalinovsky, Kamran Shamsi, Vagif Soultanov
Objectives. Helicobacter pylori infection is common and can lead to precancerous gastric lesions. Standard antibiotic therapy has a failure rate of more than 25% from antibiotic resistance. The primary aim of this observational pilot study was to test the feasibility of a large-scale clinical trial of Conifer Green Needle Complex (CGNC) to treat precancerous gastric lesions. Secondary aims were to investigate H. pylori infection, stomach function, and histopathology of the gastric mucosa. Methods. A tablet form of CGNC (extracted from Pinus sylvestris and Picea abies (L) Karst) was prescribed to 26 patients with precancerous gastric lesions (two tablets, 100 mg CGNC/tablet, three times per day for six months)...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27988924/successful-eradication-therapy-for-helicobacter-pylori-positive-atrophic-gastritis-at-the-sixth-attempt-a-case-report
#13
Ryuzo Deguchi, Koichi Shiraishi, Yoshitaka Arase, Makiko Dekiden, Hideo Shimada, Hiroshi Miyakita, Takashi Ogimi, Kazunori Myojin, Tetsuya Mine
A 74-year-old woman undergoing outpatient follow-up for reflux esophagitis and atrophic gastritis tested positive for Helicobacter pylori and underwent primary eradication therapy with lansoprazole (LPZ) 30 mg, amoxicillin (AMPC) 750 mg, and clarithromycin (CAM) 200 mg twice daily for 1 week in August 2012. A urea breath test (UBT) after this treatment revealed that eradication had failed. Secondary eradication therapy was carried out with esomeprazole (EPZ) 20 mg, AMPC 750 mg, and metronidazole (MNZ) 250 mg twice daily for 1 week, but this also failed...
December 20, 2016: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/27957783/russian-caucasians-have-a-higher-risk-of-erosive-reflux-disease-compared-with-east-asians-a-direct-endoscopic-comparison
#14
S-H Ko, M K Baeg, H S Jung, P Kim, M-G Choi
BACKGROUND: Erosive reflux disease (ERD) is prevalent in the West, and its incidence is increasing in the East. The differences between the West and East, especially in body composition, have not been investigated thoroughly. METHODS: Subjects who underwent esophagogastroduodenoscopy and body composition analysis during health screening were analyzed retrospectively. Russian Caucasians who visited Korea were propensity matched with native Koreans. Endoscopy results were analyzed to identify ERD and gastroesophageal flap valve (GEFV) status...
December 12, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27928793/-subtype-classification-and-clinicopathological-characteristics-of-gastric-neuroendocrine-neoplasms-an-analysis-of-241-cases
#15
Pan Zhang, Yu Zhang, Chi Zhang, Yanfen Shi, Jixi Liu, Qing Liu, Lili Yu, Miao Wang, Guoming Zou, Jie Lou, Jie Chen, Huangying Tan
OBJECTIVE: To study subtype classification of gastric neuroendocrine neoplasm (NEN) and their clinicopathological characteristics in order to provide reference for clinical practice. METHODS: Clinicopathological data of 241 gastric NEN patients (174 cases from China-Japan Friendship Hospital and 67 cases from The First Affiliated Hospital of Sun Yat-Sen University) between January 2011 and June 2016 were retrospectively summarized. According to serum gastrin, 24-hour intragastric pH monitoring and pathological grade, patients with gastric NEN were divided into 4 types: type I( (hypergastrinemia and achlorhydria, related to autoimmune chronic atrophic gastritis), type II( [hypergastrinemia and Zollinger-Ellison syndrome, related to gastrinoma or multiple endocrine neoplasia type I( (MEN-I()], type III( (sporadic disease with normal serum gastrin level), and type IIII( [poorly differentiated gastric neuroendocrine carcinoma (NEC) and mixed adenoneuroendocrine carcinoma (MANEC)]...
November 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27928788/-basic-and-translational-research-progress-of-gastrointestinal-neuroendocrine-neoplasmas
#16
Yuli Song, Xiaoyi Li, Tiantian Song, Guole Lin, Yuanjia Chen
Gastrointestinal neuroendocrine tumors are a group of highly heterogeneous tumors. Their incidences have increased in the Western countries as well as in Asia for years. In recent years, predominant progression has been made in the basic and translational studies on gastrointestinal neuroendocrine tumors. Gastric neuroendocrine neoplasmas are classified as four types: type I( occurs on the basis of autoimmune atrophic gastritis, type II( clinically manifests as multiple endocrine tumor type I( and Zollinger-Ellison syndrome, type III( is sporadic neuroendocrine neoplasmas, and type IIII( is neuroendocrine carcinoma...
November 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27886029/prevalence-of-h-pylori-in-gastric-biopsy-specimen-in-the-southeastern-region-of-turkey
#17
Fulya Bayındır Bilman, Mehmet Özdemir, Birol Baysal, Muhammed Güzel Kurtoğlu
INTRODUCTION: Helicobacter pylori is a Gram-negative, microaerophilic bacterium that colonizes human gastric mucosa. Gastric ulcer, duodenal ulcer, chronic atrophic gastritis, mucosa-associated lymphoid tissue lymphoma, and stomach adenocarcinoma are associated with H. pylori as the etiological agent. Cytotoxin-associated gene A (cagA), which is one of the most important virulence factors of H. pylori, encodes a 120-145 kDa protein. The prevalence of cagA genes shows differences in H...
November 24, 2016: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/27858920/clinical-risk-assessment-for-gastric-cancer-in-asymptomatic-population-after-a-health-check-up-an-individualized-consideration-of-the-risk-factors
#18
Yoo Mi Park, Jie-Hyun Kim, Su Jung Baik, Jae Jun Park, Young Hoon Youn, Hyojin Park
For the prevention of gastric cancer, the detection of risk factors associated with precancerous conditions may be more informative. The aim of this study was to identify the risk factors of gastric cancer, including precancerous conditions: atrophic gastritis (AG), intestinal metaplasia (IM), and dysplasia.The clinical and endoscopic findings of 60,261 adults who underwent gastroduodenoscopy as part of a health check-up were reviewed retrospectively. Subgroup analysis was conducted according to age, sex, cancer stage, and histology based on Lauren classification...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27851820/impact-of-helicobacter-pylori-immunoglobulin-g-levels-and-atrophic-gastritis-status-on-risk-of-metabolic-syndrome
#19
Atsushi Takeoka, Jun Tayama, Hironori Yamasaki, Masakazu Kobayashi, Sayaka Ogawa, Tatsuo Saigo, Masaki Hayashida, Susumu Shirabe
BACKGROUND: Helicobacter pylori (HP) infection is implicated in gastric and extra-gastric diseases. While gastritis-related chronic inflammation represents a known trigger of metabolic disturbances, whether metabolic syndrome (MetS) is affected by gastritis status remains unclear. We aimed to clarify the effect of HP-related gastritis on the risk of MetS. MATERIALS AND METHODS: We retrospectively enrolled patients undergoing screening for MetS between 2014 and 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27832356/risk-factors-for-intestinal-metaplasia-in-a-southeastern-chinese-population-an-analysis-of-28-745-cases
#20
Jian-Xia Jiang, Qing Liu, Bing Zhao, Hai-Han Zhang, Huai-Ming Sang, Soyfoo-Muhammad Djaleel, Guo-Xin Zhang, Shun-Fu Xu
PURPOSE: To identify risk factors for intestinal metaplasia in a southeastern Chinese population. METHODS: Subjects who underwent upper GI endoscopy and endoscopic biopsy in the First Affiliated Hospital of Nanjing Medical University from 2008 to 2013 were included into this study. Various demographic, geographic, clinical and pathological data were analyzed separately to identify risk factors for intestinal metaplasia. RESULTS: The incidence of intestinal metaplasia differed significantly in 17 municipal areas ranging from 16...
November 10, 2016: Journal of Cancer Research and Clinical Oncology
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